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Journal articles on the topic 'Lock-In spectroscopy'

Author: Grafiati

Published: 29 February 2024

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1

Koresawa, Hidenori, Kyuki Shibuya, Takeo Minamikawa, et al. "Lock-in-detection dual-comb spectroscopy." OSA Continuum 2, no. 6 (2019): 1998. http://dx.doi.org/10.1364/osac.2.001998.

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2

Chernyshov, A. K., and E. A. Chernyshova. "Diode-laser derivative spectroscopy without lock-in amplifier." Physics of Wave Phenomena 19, no. 2 (2011): 89–92. http://dx.doi.org/10.3103/s1541308x11020038.

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3

Ball, C. A. B., and A. B. Conibear. "Simulated lock‐in amplifier deep level transient spectroscopy." Review of Scientific Instruments 62, no. 11 (1991): 2831–32. http://dx.doi.org/10.1063/1.1142169.

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4

Zhang, Qinduan, Jun Chang, Zhenhua Cong, Zongliang Wang, and Fupeng Wang. "Dual Path Lock-In System for Elimination of Residual Amplitude Modulation and SNR Enhancement in Photoacoustic Spectroscopy." Sensors 18, no. 12 (2018): 4255. http://dx.doi.org/10.3390/s18124255.

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A technique for elimination of residual amplitude modulation (ERAM) in photoacoustic spectroscopy based on dual path lock-in was proposed and experimentally demonstrated. There are two lock-in amplifiers, one is for gas concentration demodulation and another for residual amplitude modulation (RAM) measurement by tuning the reference signal in different phases, and then a dual path lock-in technique based on subtraction is applied to RAM removal, improving the second harmonic profile significantly. In this system, the signal to noise ratio (SNR) increases about two times based on our dual path

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5

Holcomb, M. J., and W. A. Little. "Cascading lock‐in amplification: Application to wavelength modulation spectroscopy." Review of Scientific Instruments 63, no. 12 (1992): 5570–75. http://dx.doi.org/10.1063/1.1143383.

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6

Fonsêca, Hugo, Diego Rativa, and Ricardo Lima. "In-Loco Optical Spectroscopy through a Multiple Digital Lock-In on a Linear Charge-Coupled Device (CCD) Array." Sensors 23, no. 16 (2023): 7195. http://dx.doi.org/10.3390/s23167195.

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Accurate and reliable measurements of optical properties are crucial for a wide range of industrial and commercial applications. However, external illumination fluctuations can often make these measurements challenging to obtain. This work proposes a new technique based on digital lock-in processing that enables the use of CCD spectrometers in optical spectroscopy applications, even in uncontrolled lighting conditions. This approach leverages digital lock-in processing, performed on each pixel of the spectrometer’s CCD simultaneously, to mitigate the impact of external optical interferences. T

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7

Yanju Liu, Jianhui Song, Liang Chen, and Sheng Pan. "Design of Lock-in Amplifier Used on the Photoacoustic Spectroscopy." Journal of Convergence Information Technology 8, no. 6 (2013): 942–49. http://dx.doi.org/10.4156/jcit.vol8.issue6.112.

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8

Karami, Mohammad, Zahra Heydarinasab, and Farrokh Sarreshtedari. "Sub-Doppler dichroism as a useful tool in alkali atom hyperfine spectroscopy." Laser Physics 33, no. 12 (2023): 125701. http://dx.doi.org/10.1088/1555-6611/ad04c7.

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Abstract Analytical modeling of the sub-Doppler dichroic atomic vapor laser lock error signal shows that the slope of this error signal could be of interest for the identification of transitions in alkali atom hyperfine spectroscopy. Among four D1 line transitions of alkali atoms, the slope sign of the sub-Doppler error signal is different only for the case when the Landé g-factor is negative for both the ground and excited states. The analytical model used, which includes all sublevel transitions, shows very good agreement with the experimental spectroscopy results. The use of this technique

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9

Schlierf, Michael, Felix Berkemeier, and Matthias Rief. "Direct Observation of Active Protein Folding Using Lock-in Force Spectroscopy." Biophysical Journal 93, no. 11 (2007): 3989–98. http://dx.doi.org/10.1529/biophysj.107.114397.

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10

Ardekani, Hossein, Ryan L. Wilmington, Mounika Vutukuru, et al. "Broadband micro-transient absorption spectroscopy enabled by improved lock-in amplification." Review of Scientific Instruments 92, no. 10 (2021): 104706. http://dx.doi.org/10.1063/5.0060244.

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11

Walther, Frans J., and Alan J. Waring. "Structure and Function of Canine SP-C Mimic Proteins in Synthetic Surfactant Lipid Dispersions." Biomedicines 12, no. 1 (2024): 163. http://dx.doi.org/10.3390/biomedicines12010163.

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Lung surfactant is a mixture of lipids and proteins and is essential for air breathing in mammals. The hydrophobic surfactant proteins B and C (SP-B and SP-C) assist in reducing surface tension in the lung alveoli by organizing the surfactant lipids. SP-B deficiency is life-threatening, and a lack of SP-C can lead to progressive interstitial lung disease. B-YL (41 amino acids) is a highly surface-active, sulfur-free peptide mimic of SP-B (79 amino acids) in which the four cysteine residues are replaced by tyrosine. Mammalian SP-C (35 amino acids) contains two cysteine-linked palmitoyl groups a

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12

Balgos, M. H., N. Hayazawa, M. Tani, and T. Tanaka. "Megahertz repetition rate-based lock-in detection scheme for rapid data acquisition in terahertz time domain spectroscopy." Review of Scientific Instruments 94, no. 4 (2023): 043002. http://dx.doi.org/10.1063/5.0138938.

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We report a fast pump modulation scheme in a terahertz time domain spectroscopy (THz-TDS) system by utilizing the intensity modulation from the megahertz repetition rate of the pump pulse for lock-in detection. In conventional THz-TDS, the modulation required for the high signal-to-noise ratio lock-in detection is achieved through the use of an optical chopper or an AC bias. Here, we propose the use of an electro-optic modulator (EOM), operated as a pulse picker, to vary the repetition rate of the pump pulse, relative to the probe pulse, allowing us to directly use the megahertz laser repetiti

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13

Liu, Yan Li, and Rui Zhang. "AD630 Lock-In Amplifier Circuit for Weak Signal." Advanced Materials Research 482-484 (February 2012): 975–80. http://dx.doi.org/10.4028/www.scientific.net/amr.482-484.975.

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Lock-in amplifying (LIA) is one of important techniques of picking up weak signals buried in the noise, and is the core component of Tunable Diode Laser Absorption Spectroscopy (TDLAS) technology. Then we design a small size, dual phase lock-in amplifier (LIA) integrated circuit. This paper is based on the phase-sensitive detector AD630, together with the phase-locked loop (PLL) circuit (74HC4046) and the active filter (MAX275) the value of Q and the center frequency of which could be adjusted. The output signals were collected by A/D converter and dedicated high-resolution data acquisition ca

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14

Borkowski, Maciej, Ewa B. Skrodzka, and Bogumił B. J. Linde. "COMPARISON OF SINGLE AND DUAL-PHASE LOCK-IN AMPLIFIERS FOR PHOTOACOUSTIC SPECTROSCOPY." Instrumentation Science & Technology 42, no. 4 (2014): 469–74. http://dx.doi.org/10.1080/10739149.2014.888671.

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15

Albertini, A., and W. Kleemann. "Analogue and digital lock-in techniques for very-low-frequency impedance spectroscopy." Measurement Science and Technology 8, no. 6 (1997): 666–72. http://dx.doi.org/10.1088/0957-0233/8/6/014.

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16

Ragni, A., G. Sciortino, M. Sampietro, G. Ferrari, and D. Polli. "Multi-channel lock-in based differential front-end for broadband Raman spectroscopy." Integration 67 (July 2019): 44–49. http://dx.doi.org/10.1016/j.vlsi.2019.03.001.

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17

Fangnon, Eric, Evgenii Malitckii, Yuriy Yagodzinskyy, and Pedro Vilaça. "Improved Accuracy of Thermal Desorption Spectroscopy by Specimen Cooling during Measurement of Hydrogen Concentration in a High-Strength Steel." Materials 13, no. 5 (2020): 1252. http://dx.doi.org/10.3390/ma13051252.

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Thermal desorption spectroscopy (TDS) is a powerful method for the measurement of hydrogen concentration in metallic materials. However, hydrogen loss from metallic samples during the preparation of the measurement poses a challenge to the accuracy of the results, especially in materials with high diffusivity of hydrogen, like ferritic and ferritic-martensitic steels. In the present paper, the effect of specimen cooling during the experimental procedure, as a tentative to reduce the loss of hydrogen during air-lock vacuum pumping for one high-strength steel of 1400 MPa, is evaluated. The resul

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18

BELLINI, M., S. CAVALIERI, C. CORSI, and M. MATERAZZI. "Towards high-resolution spectroscopy in the XUV with phase-locked harmonic pulses." Laser and Particle Beams 19, no. 1 (2001): 29–33. http://dx.doi.org/10.1017/s0263034601191044.

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We report the results of measurements aimed to check the phase lock of time-delayed, collinear, harmonic pulses and to verify the possibility of performing Ramsey-like spectroscopy in the XUV. We demonstrate that for harmonics of medium order and for the peak intensities available with our laser system, the generation of collinear phase-locked harmonic pulses is indeed possible and that such pulses can be used to achieve high-resolution spectroscopy in the short-wavelength region.

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19

Matsuoka, Leo. "Artifact side peaks in saturated absorption spectroscopy caused by inappropriate lock-in amplification." Japanese Journal of Applied Physics 62, no. 10 (2023): 108006. http://dx.doi.org/10.35848/1347-4065/ad03a6.

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Abstract Saturated absorption spectroscopy is a powerful technique that provides valuable information about gas-phase atomic targets, including not only the precise positions of transitions but also the effects of velocity-changing collisions, which manifest as changes in the shape of the peaks. However, using a lock-in amplifier inappropriately can generate artifact side peaks, potentially leading to a misinterpretation of results. To investigate the emergence of these artifacts, we conducted numerical calculations based on the basic Lambert–Beer’s law. Our model reproduced the artifact side

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20

Erskine, Steven R., C. Michael Foley, and Donald R. Bobbitt. "Single-Laser, Single-Beam Pump/Probe Thermal Lens Spectroscopy." Applied Spectroscopy 41, no. 7 (1987): 1189–93. http://dx.doi.org/10.1366/0003702874447716.

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A unique design for a thermal lens photometer based on a single-laser/single-beam configuration is presented. The system is compatible with lock-in detection and uses a pair of acoustooptic modulators to temporally separate the pump and probe events. A minimum measurable absorbance of 6 × 10−6 cm−1 is reported. Limitations to the use of acoustooptic modulation at high absorbances are discussed.

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21

Waddington, John L., Eadbhard O'Callaghan, Conall Larkin, Oonagh Redmond, John Stack, and Joseph T. Ennis. "Magnetic Resonance Imaging and Spectroscopy in Schizophrenia." British Journal of Psychiatry 157, S9 (1990): 56–65. http://dx.doi.org/10.1192/s000712500029185x.

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In this new era of structural and functional neuroimaging technologies, it is the unsurpassed anatomical resolution of magnetic resonance imaging (MRI) (Andreasen, 1989; and Besson, this supplement) that has resulted in a new generation of studies on cerebral morphology in schizophrenia. With the recent development of whole-body magnets of very high (⩾ 1.5T) and uniform field strength, it has become possible to extend the scope of this approach to include measurement of certain fundamental neurochemical processes, via magnetic resonance spectroscopy (MRS: Hubesch et al, 1989; Lock et al, this

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22

Sciortino, Giuseppe, Andrea Ragni, Alejandro De la Cadena, et al. "Four-Channel Differential Lock-in Amplifiers With Autobalancing Network for Stimulated Raman Spectroscopy." IEEE Journal of Solid-State Circuits 56, no. 6 (2021): 1859–70. http://dx.doi.org/10.1109/jssc.2020.3046484.

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23

Wang, Wubin, Dong Chen, Wenxi Yao, Wei Chen, and Zhengyu Lu. "Fast lock-in amplifier electrochemical impedance spectroscopy for big capacity lead-acid battery." Journal of Energy Storage 40 (August 2021): 102693. http://dx.doi.org/10.1016/j.est.2021.102693.

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24

Wojtkiewicz, Stanislaw, Karolina Bejm, and Adam Liebert. "Lock-in functional near-infrared spectroscopy for measurement of the haemodynamic brain response." Biomedical Optics Express 13, no. 4 (2022): 1869. http://dx.doi.org/10.1364/boe.448038.

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25

Uhl, D., L. Bruder, and F. Stienkemeier. "A flexible and scalable, fully software-based lock-in amplifier for nonlinear spectroscopy." Review of Scientific Instruments 92, no. 8 (2021): 083101. http://dx.doi.org/10.1063/5.0059740.

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26

Li, Nan, Wei Wang, Hui Xu, Hongqi Yu, Jietao Diao, and David D. U. Li. "Wide-Bandwidth Biological Impedance Spectroscopy System Based on the Digital Lock-In Technique." Spectroscopy Letters 46, no. 7 (2013): 476–82. http://dx.doi.org/10.1080/00387010.2012.705801.

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27

Scott, J. F. "New results in incommensurate crystals: Kink diffusion and long-period lock-in phases." Journal of Raman Spectroscopy 17, no. 1 (1986): 151–54. http://dx.doi.org/10.1002/jrs.1250170130.

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28

Qin, Jianhuan, Zhiming Huang, Yujian Ge, Yun Hou, and Junhao Chu. "Tandem demodulation lock-in amplifier based on digital signal processor for dual-modulated spectroscopy." Review of Scientific Instruments 80, no. 3 (2009): 033112. http://dx.doi.org/10.1063/1.3098948.

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29

Bertrand, Mathieu, Aleksandr Shlykov, Mehran Shahmohamadi, Mattias Beck, Stefan Willitsch, and Jérôme Faist. "High-Power, Narrow-Linewidth Distributed-Feedback Quantum-Cascade Laser for Molecular Spectroscopy." Photonics 9, no. 8 (2022): 589. http://dx.doi.org/10.3390/photonics9080589.

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Quantum cascade lasers are versatile light sources in the mid-infrared range for molecular spectroscopy which find a wide range of applications from high-resolution studies to sensing. While devices with either high power or narrow spectral linewidth have previously been reported, there is still a lack of sources combining both of these characteristics which are particularly important for precision measurements of weak spectroscopic transitions. In this article, we describe and characterize a novel master-oscillator power-amplifier distributed-feedback quantum cascade laser designed to fill th

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30

Erskine, Steven R., and Donald R. Bobbitt. "Theoretical and Experimental Investigation of the Relationship between Aperture Dimension and Signal-to-Noise Optimization in Thermal Lens Spectroscopy." Applied Spectroscopy 42, no. 2 (1988): 331–35. http://dx.doi.org/10.1366/0003702884428257.

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The effect of three types of experimental laser noise on conventional thermal lens spectroscopy are considered. Theoretical calculations of noise and signal-to-noise ratio as a function of aperture size are included to determine ideal aperture dimensions for systems limited by laser pointing instabilities, flicker noise, and/or shot noise. Experimentally determined noise curves are also presented and discussed in the context of the theoretical results. The results show that for most thermal lens configurations based on lock-in detection, optimum S/N is obtained at an aperture-to-beam-size rati

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31

KOBAYASHI, Hiroyuki. "Reducing Particle Contamination During Pump-down in Load Lock Chamber." Journal of the Vacuum Society of Japan 53, no. 10 (2010): 568–72. http://dx.doi.org/10.3131/jvsj2.53.568.

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32

Rico, Felix, Andreas Russek, Laura González, Helmut Grubmüller, and Simon Scheuring. "Heterogeneous and rate-dependent streptavidin–biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations." Proceedings of the National Academy of Sciences 116, no. 14 (2019): 6594–601. http://dx.doi.org/10.1073/pnas.1816909116.

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Receptor–ligand interactions are essential for biological function and their binding strength is commonly explained in terms of static lock-and-key models based on molecular complementarity. However, detailed information on the full unbinding pathway is often lacking due, in part, to the static nature of atomic structures and ensemble averaging inherent to bulk biophysics approaches. Here we combine molecular dynamics and high-speed force spectroscopy on the streptavidin–biotin complex to determine the binding strength and unbinding pathways over the widest dynamic range. Experiment and simula

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33

Chugh, Vinit Kumar, Kai Wu, Venkatramana D. Krishna, et al. "Magnetic Particle Spectroscopy with One-Stage Lock-In Implementation for Magnetic Bioassays with Improved Sensitivities." Journal of Physical Chemistry C 125, no. 31 (2021): 17221–31. http://dx.doi.org/10.1021/acs.jpcc.1c05126.

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34

Al Mohtar, A., J. Vaillant, Z. Sedaghat, et al. "Generalized lock-in detection for interferometry: application to phase sensitive spectroscopy and near-field nanoscopy." Optics Express 22, no. 18 (2014): 22232. http://dx.doi.org/10.1364/oe.22.022232.

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35

Messerle, Barbara A., Gerhard Wider, Gottfried Otting, Christoph Weber, and Kurt Wüthrich. "Solvent suppression using a spin lock in 2D and 3D NMR spectroscopy with H2O solutions." Journal of Magnetic Resonance (1969) 85, no. 3 (1989): 608–13. http://dx.doi.org/10.1016/0022-2364(89)90252-7.

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36

OTTING, G. "ChemInform Abstract: Use of High Power Spin-Lock Purge Pulses in High Resolution NMR Spectroscopy." ChemInform 29, no. 41 (2010): no. http://dx.doi.org/10.1002/chin.199841313.

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37

Monteiro, Fábio D. R., and Peter Stallinga. "Using an Off-the-Shelf Lock-In Detector for Admittance Spectroscopy in the Study of Plants." Agricultural Sciences 11, no. 04 (2020): 390–416. http://dx.doi.org/10.4236/as.2020.114023.

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38

Gaddy, M., V. Kuryatkov, V. Meyers, et al. "Structural, Morphological, Optical and Electrical Properties of Bulk (0001) GaN:Fe Wafers." MRS Advances 3, no. 3 (2018): 179–84. http://dx.doi.org/10.1557/adv.2018.234.

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ABSTRACTCharacterization of three vendor’s bulk semi-insulating GaN:Fe wafers, grown by either hydride vapor phase epitaxy or the ammonothermal method, was performed using: scanning electron microscopy, secondary ion mass spectroscopy, high resolution X-ray diffraction, cathodoluminescence, photoluminescence, and high voltage testing. Although the Fe doping level is significantly different for each growth method, both are promising for the fabrication of PCSS devices operating in the lock-on mode.

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39

Bellaiche-Sharpe, P., K. M. Gough, B. J. Schattka, et al. "Real-Time Photoacoustic Signal Analysis in a Gas-Phase Spectrophone: A Feasibility Study." Applied Spectroscopy 50, no. 11 (1996): 1366–72. http://dx.doi.org/10.1366/0003702963904647.

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A digital signal processing (DSP) system has been constructed for the acquisition of intracavity dye laser photoacoustic spectra (ICL-PAS). The DSP system permits observation of the real-time PA pulse, an arrangement which facilitates the adjustment of all spectral acquisition parameters as well as signal processing for noise reduction. Sample spectra of the real-time PA pulse illustrate the improvements possible with Fourier filtering and time-averaging. Spectra of the region of the fifth CH stretching overtone of ethene, benzene, and propane in the gas phase are presented. The system offers

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40

Andersson, Mats, Linda Persson, Tomas Svensson, and Sune Svanberg. "Flexible lock-in detection system based on synchronized computer plug-in boards applied in sensitive gas spectroscopy." Review of Scientific Instruments 78, no. 11 (2007): 113107. http://dx.doi.org/10.1063/1.2813346.

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41

Jäger, Martin, Paul Schuler, Hartmut B. Stegmann, and Antal Rockenbauer. "Molecular Recognition Analyzed by Observing Intramolecular Interconversion with EPR Spectroscopy." Zeitschrift für Naturforschung B 53, no. 12 (1998): 1511–19. http://dx.doi.org/10.1515/znb-1998-1215.

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Abstract Molecular recognition between Rebek’s cleft R and 4-(2-benzimidazolyl)-aminomethyl-2,6-di-rm-butyl-phenol (Bi) is investigated by means of EPR spectroscopy. Their specific inter-molecular interactions are distinguished from non-specific interactions represented by mere protonation on addition of benzoic acid. Both interactions are related to intramolecular in terconversions at the C∞-atom of Bi*, where a two-jump mechanism is found for free and protonated Bi* and a two-site exchange for the complexed ligand. While NMR spectroscopy indicates the existence of 1:1 and 1:2 receptor-subst

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42

Zhou, Lu Jun, Qiang Chen, and Jian Qing Fang. "Acoustic Resonance Spectroscopy for Hazards Materials Classification." Applied Mechanics and Materials 427-429 (September 2013): 686–90. http://dx.doi.org/10.4028/www.scientific.net/amm.427-429.686.

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In this paper, a measure system based on acoustic resonance is developed for hazards materials classification. It employs the lock-in amplifier as core processor to collect the acoustic resonance spectroscopy (ARS) of sealed containers which storied hazards materials. The transmitter and receiver are coupled externally to the wall of the container. The transmitter generates the sound by using a swept frequency source. The receiver on the opposite side of the wall of the container can detect the transmitted signal. The acoustic properties of hazards materials such as velocity and attenuation ca

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43

Augulis, Ramūnas, and Donatas Zigmantas. "Two-dimensional electronic spectroscopy with double modulation lock-in detection: enhancement of sensitivity and noise resistance." Optics Express 19, no. 14 (2011): 13126. http://dx.doi.org/10.1364/oe.19.013126.

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44

Mahnke, Peter. "Characterization of a commercial software defined radio as high frequency lock-in amplifier for FM spectroscopy." Review of Scientific Instruments 89, no. 1 (2018): 013113. http://dx.doi.org/10.1063/1.4999552.

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45

Zhao, Bo, Alexandar L. Hansen та Qi Zhang. "Characterizing Slow Chemical Exchange in Nucleic Acids by Carbon CEST and Low Spin-Lock FieldR1ρNMR Spectroscopy". Journal of the American Chemical Society 136, № 1 (2013): 20–23. http://dx.doi.org/10.1021/ja409835y.

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46

Dethomas, F. A., Cecil Dybowski, and Harvey S. Gold. "Effect of Modulation Source Properties upon Signal-To-Noise Ratios of Inelastic Electron Tunneling Spectra." Applied Spectroscopy 40, no. 8 (1986): 1180–83. http://dx.doi.org/10.1366/0003702864507585.

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Lock-in amplification using ac modulation and second-harmonic detection is routinely employed in such techniques as ac polarography, ac voltammetry, and inelastic electron tunneling spectroscopy (IETS). Properties of the modulation source are shown in the present IET studies to limit the obtainable signal-to-noise ratio of a spectrum. A single inelastic electron tunneling junction is used to demonstrate the effect of various commercial modulation sources on the IET spectrum of benzoic acid on alumina. With all other parameters being held constant, the signal-to-noise ratio of the IET spectrum

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47

Rezaeian, Khatereh, Hamid Khanmohammadi, and Nafiseh Shabani. "Sequential Detection of CN- and HSO4- Anions in an Aqueous Environment Utilizing a New Colorimetric Azoimine Receptor: Mimicking Logic Gate Behaviour and a Security Keypad Lock." Australian Journal of Chemistry 71, no. 5 (2018): 389. http://dx.doi.org/10.1071/ch18048.

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A new isonicotiamide-based azoimine receptor has been successfully devised and synthesised for dual-recognition of CN− and HSO4− anions in aqueous media (3 : 2 DMSO–water solution). The devised azomethine probe detected lethal cyanide ions under UV-vis spectroscopy through the rapid appearance of an orange colour. More importantly, the colour and spectroscopic changes of the devised chemosensor could be revived upon the addition of HSO4− to the sensor containing cyanide ions. Furthermore, other surveyed anions failed to induce a similar response. Interestingly, based on changes in absorption i

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48

Zhang, Xueshi, Lixian Liu, Le Zhang, et al. "A compact portable photoacoustic spectroscopy sensor for multiple trace gas detection." Journal of Applied Physics 131, no. 17 (2022): 174501. http://dx.doi.org/10.1063/5.0088257.

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A compact, highly sensitive, and cost-effective photoacoustic spectroscopic sensor for multiple trace gas detection was reported with a self-designed compact distributed feedback laser array and a 2-channel dual phase field programmable gate array based digital lock-in amplifier, only twentieth in size and weight of the commercial instruments. The capability of the portable sensor was verified by measuring CH4 and C2H2 simultaneously. With an integrated nonlocal means algorithm denoising, noise-equivalent concentrations were achieved as 6.89 ppb for CH4 and 2.74 ppb for C2H2, respectively, cor

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49

Shiraki, Takuma, Takashi S. Kodama, Sayaka Shiki, Tatsuo Nakagawa та Hisato Jingami. "Spectroscopic analyses of the binding kinetics of 15d-PGJ2 to the PPARγ ligand-binding domain by multi-wavelength global fitting". Biochemical Journal 393, № 3 (2006): 749–55. http://dx.doi.org/10.1042/bj20050930.

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PPARγ (peroxisome proliferator-activated receptor γ) is a nuclear receptor that is activated by natural lipid metabolites, including 15d-PGJ2 (15-deoxy-Δ12,14-prostaglandin J2). We previously reported that several oxidized lipid metabolites covalently bind to PPARγ through a Michael-addition to activate transcription. To separate the ligand-entering (dock) and covalent-binding (lock) steps in PPARγ activation, we investigated the binding kinetics of 15d-PGJ2 to the PPARγ LBD (ligand-binding domain) by stopped-flow spectroscopy. We analysed the spectral changes of 15d-PGJ2 by multi-wavelength g

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50

Yao, Yikun, Xinjia Zhao, Xiangqian Tang, Jianmei Li, Xinyan Shan, and Xinghua Lu. "Laser etching of 2D materials with single-layer precision up to ten layers." Journal of Laser Applications 34, no. 4 (2022): 042051. http://dx.doi.org/10.2351/7.0000848.

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Abstract:

Patterned 2D materials with layer-controlled thickness and precise lateral resolution are of great potential for many applications. Laser etching is a promising technique for large-scale patterning of 2D materials, but better control in film thickness is strongly desired. Here, we explore the dynamic characteristics in the laser etching process in which a local temperature lock phenomenon is observed as laser power reaches the etching threshold. A layer-by-layer etching strategy is then developed based on the temporal evolution of the local temperature as measured by in-situ Raman spectroscopy

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