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1

Medeiros, Wladimir M., Mari C. T. Fernandes, Diogo P. Azevedo, et al. "Oxygen delivery-utilization mismatch in contracting locomotor muscle in COPD: peripheral factors." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 308, no. 2 (2015): R105—R111. http://dx.doi.org/10.1152/ajpregu.00404.2014.

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Central cardiorespiratory and gas exchange limitations imposed by chronic obstructive pulmonary disease (COPD) impair ambulatory skeletal muscle oxygenation during whole body exercise. This investigation tested the hypothesis that peripheral factors per se contribute to impaired contracting lower limb muscle oxygenation in COPD patients. Submaximal neuromuscular electrical stimulation (NMES; 30, 40, and 50 mA at 50 Hz) of the quadriceps femoris was employed to evaluate contracting skeletal muscle oxygenation while minimizing the influence of COPD-related central cardiorespiratory constraints.
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LEGRAND, RENAUD, ALEXANDRE MARLES, FABRICE PRIEUR, STEFANO LAZZARI, NICOLAS BLONDEL, and PATRICK MUCCI. "Related Trends in Locomotor and Respiratory Muscle Oxygenation during Exercise." Medicine & Science in Sports & Exercise 39, no. 1 (2007): 91–100. http://dx.doi.org/10.1249/01.mss.0000241638.90348.67.

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3

Borghi-Silva, Audrey, Cláudia Carrascosa, Cristino Carneiro Oliveira, et al. "Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 6 (2008): H2465—H2472. http://dx.doi.org/10.1152/ajpheart.91520.2007.

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Blood flow requirements of the respiratory muscles (RM) increase markedly during exercise in chronic heart failure (CHF). We reasoned that if the RM could subtract a fraction of the limited cardiac output (QT) from the peripheral muscles, RM unloading would improve locomotor muscle perfusion. Nine patients with CHF (left ventricle ejection fraction = 26 ± 7%) undertook constant-work rate tests (70-80% peak) receiving proportional assisted ventilation (PAV) or sham ventilation. Relative changes (Δ%) in deoxy-hemoglobyn, oxi-Hb ([O2Hb]), tissue oxygenation index, and total Hb ([HbTOT], an index
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4

Forgue, J., A. Legeay, and J. C. Massabuau. "Is the resting rate of oxygen consumption of locomotor muscles in crustaceans limited by the low blood oxygenation strategy?" Journal of Experimental Biology 204, no. 5 (2001): 933–40. http://dx.doi.org/10.1242/jeb.204.5.933.

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Numerous water-breathers exhibit a gas-exchange regulation strategy that maintains O(2) partial pressure, P(O2), in the arterial blood within the range 1–3 kPa at rest during the daytime. In a night-active crustacean, we examined whether this could limit the rate of O(2)consumption (M(O2)) of locomotor muscles and/or the whole body as part of a coordinated response to energy conservation. In the crayfish Astacus leptodactylus, we compared the in vitro relationship between the M(O2) of locomotor muscles as a function of the extracellular P(O2) and P(CO2) and in vivo circadian changes in blood g
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5

Tong, Tom K., Hua Lin, Alison McConnell, Roger Eston, Jun Zheng, and Jinlei Nie. "Respiratory and locomotor muscle blood-volume and oxygenation kinetics during intense intermittent exercise." European Journal of Sport Science 12, no. 4 (2012): 321–30. http://dx.doi.org/10.1080/17461391.2011.566364.

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6

Brkic, Predrag, Mirjana Stojiljkovic, Tomislav Jovanovic, et al. "Hyperbaric oxygenation improves locomotor ability by enhancing neuroplastic responses after cortical ablation in rats." Brain Injury 26, no. 10 (2012): 1273–84. http://dx.doi.org/10.3109/02699052.2012.667593.

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7

Hirai, Daniel M., Joshua H. Jones, Joel T. Zelt, et al. "Oral N-acetylcysteine and exercise tolerance in mild chronic obstructive pulmonary disease." Journal of Applied Physiology 122, no. 5 (2017): 1351–61. http://dx.doi.org/10.1152/japplphysiol.00990.2016.

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Heightened oxidative stress is implicated in the progressive impairment of skeletal muscle vascular and mitochondrial function in chronic obstructive pulmonary disease (COPD). Whether accumulation of reactive oxygen species contributes to exercise intolerance in the early stages of COPD is unknown. The purpose of the present study was to determine the effects of oral antioxidant treatment with N-acetylcysteine (NAC) on respiratory, cardiovascular, and locomotor muscle function and exercise tolerance in patients with mild COPD. Thirteen patients [forced expiratory volume in 1 s (FEV1)-to-forced
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8

Hirai, Daniel M., Joel T. Zelt, Joshua H. Jones, et al. "Dietary nitrate supplementation and exercise tolerance in patients with heart failure with reduced ejection fraction." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 312, no. 1 (2017): R13—R22. http://dx.doi.org/10.1152/ajpregu.00263.2016.

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Endothelial dysfunction and reduced nitric oxide (NO) signaling are key abnormalities leading to skeletal muscle oxygen delivery-utilization mismatch and poor physical capacity in patients with heart failure with reduced ejection fraction (HFrEF). Oral inorganic nitrate supplementation provides an exogenous source of NO that may enhance locomotor muscle function and oxygenation with consequent improvement in exercise tolerance in HFrEF. Thirteen patients (left ventricular ejection fraction ≤40%) were enrolled in a double-blind, randomized crossover study to receive concentrated nitrate-rich (n
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9

Amann, Markus, Marlowe W. Eldridge, Andrew T. Lovering, Michael K. Stickland, David F. Pegelow, and Jerome A. Dempsey. "Arterial oxygenation influences central motor output and exercise performance via effects on peripheral locomotor muscle fatigue in humans." Journal of Physiology 575, no. 3 (2006): 937–52. http://dx.doi.org/10.1113/jphysiol.2006.113936.

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10

Boone, Jan, Kristof Vandekerckhove, Ilse Coomans, Fabrice Prieur, and Jan G. Bourgois. "An integrated view on the oxygenation responses to incremental exercise at the brain, the locomotor and respiratory muscles." European Journal of Applied Physiology 116, no. 11-12 (2016): 2085–102. http://dx.doi.org/10.1007/s00421-016-3468-x.

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11

Vandekerckhove, Kristof, Ilse Coomans, Annelies Moerman, Daniel De Wolf, and Jan Boone. "Characterizing cerebral and locomotor muscle oxygenation to incremental ramp exercise in healthy children: relationship with pulmonary gas exchange." European Journal of Applied Physiology 116, no. 11-12 (2016): 2345–55. http://dx.doi.org/10.1007/s00421-016-3486-8.

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12

Silva-Batista, Carla, Jumes Lira, Daniel Boari Coelho, et al. "Mesencephalic Locomotor Region and Presynaptic Inhibition during Anticipatory Postural Adjustments in People with Parkinson’s Disease." Brain Sciences 14, no. 2 (2024): 178. http://dx.doi.org/10.3390/brainsci14020178.

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Individuals with Parkinson’s disease (PD) and freezing of gait (FOG) have a loss of presynaptic inhibition (PSI) during anticipatory postural adjustments (APAs) for step initiation. The mesencephalic locomotor region (MLR) has connections to the reticulospinal tract that mediates inhibitory interneurons responsible for modulating PSI and APAs. Here, we hypothesized that MLR activity during step initiation would explain the loss of PSI during APAs for step initiation in FOG (freezers). Freezers (n = 34) were assessed in the ON-medication state. We assessed the beta of blood oxygenation level-de
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13

Richard, Philippe, and François Billaut. "Effects of inspiratory muscle warm-up on locomotor muscle oxygenation in elite speed skaters during 3000 m time trials." European Journal of Applied Physiology 119, no. 1 (2018): 191–200. http://dx.doi.org/10.1007/s00421-018-4015-8.

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14

Caruso, Flavia Rossi, Bruno Archiza, Daniela Kuguimoto Andaku, et al. "Effects of acute inspiratory loading during treadmill running on cerebral, locomotor and respiratory muscle oxygenation in women soccer players." Respiratory Physiology & Neurobiology 281 (October 2020): 103488. http://dx.doi.org/10.1016/j.resp.2020.103488.

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15

Mišić, Nataša Ž., Mirko Ostojić, Saša Cvetković, et al. "Wavelet Analysis of Respiratory Muscle sEMG Signals during the Physiological Breakpoint of Static Dry End-Expiratory Breath-Holding in Naive Apneists: A Pilot Study." Sensors 23, no. 16 (2023): 7200. http://dx.doi.org/10.3390/s23167200.

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The wavelet spectral characteristics of three respiratory muscle signals (scalenus (SC), parasternal intercostal (IC), and rectus abdominis (RA)) and one locomotor muscle (brachioradialis (BR)) were analyzed in the time–frequency (T-F) domain during voluntary breath-holding (BH), with a focus on the physiological breakpoint that is commonly considered the first involuntary breathing movement (IBM) that signals the end of the easy-going phase of BH. The study was performed for an end-expiratory BH physiological breaking point maneuver on twelve healthy, physically active, naive breath-holders/a
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16

Amann, Markus, Mark S. Regan, Majd Kobitary, et al. "Impact of pulmonary system limitations on locomotor muscle fatigue in patients with COPD." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 299, no. 1 (2010): R314—R324. http://dx.doi.org/10.1152/ajpregu.00183.2010.

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We examined the effects of respiratory muscle work [inspiratory (Wr-insp); expiratory (Wr-exp)] and arterial oxygenation (SpO2) on exercise-induced locomotor muscle fatigue in patients with chronic obstructive pulmonary disease (COPD). Eight patients (FEV, 48 ± 4%) performed constant-load cycling to exhaustion (Ctrl; 9.8 ± 1.2 min). In subsequent trials, the identical exercise was repeated with 1) proportional assist ventilation + heliox (PAV); 2) heliox (He:21% O2); 3) 60% O2 inspirate (hyperoxia); or 4) hyperoxic heliox mixture (He:40% O2). Five age-matched healthy control subjects performed
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17

Huang, Lixin, Maheshkumar P. Mehta, Anil Nanda, and John H. Zhang. "The role of multiple hyperbaric oxygenation in expanding therapeutic windows after acute spinal cord injury in rats." Journal of Neurosurgery: Spine 99, no. 2 (2003): 198–205. http://dx.doi.org/10.3171/spi.2003.99.2.0198.

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Object. Hyperbaric oxygenation (HBO) therapy has been reported to improve neurological recovery after spinal cord injury (SCI). In the present study, the authors examined whether multiple HBO therapy can expand the therapeutic window after acute SCI. Methods. Seventy rats were randomly assigned to seven groups: sham surgery; SCI without treatment; single HBO treatment beginning at 30 minutes, 3 hours, and 6 hours after SCI; and multiple HBO treatments starting at 6 and 24 hours postinjury. Mild SCI was induced by adjusting the height of a weight drop (10 g) to 6.25 mm above the exposed spinal
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18

Campos-Pires, Rita, Haldis Onggradito, Eszter Ujvari, et al. "8 Xenon is neuroprotective, improves outcome and promotes beneficial early neuroinflammation in a rat model of severe traumatic brain injury." BMJ Military Health 169, no. 2 (2023): e1.8. http://dx.doi.org/10.1136/military-2022-ukdsr.8.

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IntroductionTraumatic brain injury (TBI) affects both young and elderly populations and results in a significant global healthcare burden. TBI patients often suffer from costly long-term neurological and cognitive problems that reduce quality of life and ability to work, including motor deficits, gait abnormalities, memory impairments and anxiety. Current clinical practice for TBI is largely supportive, centred on non-specific endpoints such as management of tissue oxygenation, cerebral perfusion pressure and intracranial pressure. At present there are no clinically validated drug treatments a
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19

Anderson, Garret R., Rafael Lujan та Kirill A. Martemyanov. "Changes in Striatal Signaling Induce Remodeling of RGS Complexes Containing Gβ5 and R7BP Subunits". Molecular and Cellular Biology 29, № 11 (2009): 3033–44. http://dx.doi.org/10.1128/mcb.01449-08.

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ABSTRACT Neurotransmitter signaling via G protein coupled receptors is crucially controlled by regulators of G protein signaling (RGS) proteins that shape the duration and extent of the cellular response. In the striatum, members of the R7 family of RGS proteins modulate signaling via D2 dopamine and μ-opioid receptors controlling reward processing and locomotor coordination. Recent findings have established that R7 RGS proteins function as macromolecular complexes with two subunits: type 5 G protein β (Gβ5) and R7 binding protein (R7BP). In this study, we report that the subunit compositions
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20

Mosser, Nina, Markus Tilp, Gudrun Schappacher-Tilp, Annika Kruse, and Gerhard Tschakert. "Comparison of local muscle oxygenation and whole-body VO2 during incremental exercise." Current Issues in Sport Science (CISS) 9, no. 4 (2024): 043. http://dx.doi.org/10.36950/2024.4ciss043.

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The use of near-infrared spectroscopy (NIRS) in sports science has become increasingly important in the past few years (Perrey et al., 2024). One application is to determine thresholds from different NIRS parameters like oxygenated (O2Hb) or deoxygenated (HHb) hemoglobin to distinguish between hard and severe-intensity exercise (Caen et al., 2018). Such applications are frequently validated by comparison to established threshold determination concepts. However, it is not yet known which of the two parameters is more closely related to classical concepts. Therefore, the aim of this project was
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21

Marillier, Mathieu, Anne-Catherine Bernard, Samuel Verges, Onofre Moran-Mendoza, Denis E. O'Donnell, and José Alberto Neder. "Oxygen supplementation during exercise improves leg muscle fatigue in chronic fibrotic interstitial lung disease." Thorax 76, no. 7 (2021): 672–80. http://dx.doi.org/10.1136/thoraxjnl-2020-215135.

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BackgroundExercise-induced hypoxaemia is a hallmark of chronic fibrotic interstitial lung disease (f-ILD). It remains unclear whether patients’ severe hypoxaemia may exaggerate locomotor muscle fatigue and, if so, to what extent oxygen (O2) supplementation can ameliorate these abnormalities.MethodsFifteen patients (12 males, 9 with idiopathic pulmonary fibrosis) performed a constant-load (60% peak work rate) cycle test to symptom limitation (Tlim) while breathing medical air. Fifteen age-matched and sex-matched controls cycled up to patients’ Tlim. Patients repeated the exercise test on supple
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22

Tuesta, Marcelo, Rodrigo Yáñez-Sepúlveda, Matías Monsalves-Álvarez, et al. "Muscle Oxygen Extraction during Vascular Occlusion Test in Physically Very Active versus Inactive Healthy Men: A Comparative Study." Journal of Functional Morphology and Kinesiology 9, no. 2 (2024): 57. http://dx.doi.org/10.3390/jfmk9020057.

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An increase in the delivery and use of oxygen to the musculature in physically active subjects are determinants of improving health-related aerobic capacity. Additional health benefits, such as an increase in the muscle mass and a decrease in fat mass, principally in the legs, could be achieved with weekly global physical activity levels of more than 300 min. The objective was to compare the muscle vascular and metabolic profiles of physically very active and inactive subjects. Twenty healthy men participated in the study; ten were assigned to the physically very active group (25.5 ± 4.2 years
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23

Matsukawa, Kanji, Ryota Asahara, Kei Ishii, et al. "Increased prefrontal oxygenation prior to and at the onset of over-ground locomotion in humans." Journal of Applied Physiology 129, no. 5 (2020): 1161–72. http://dx.doi.org/10.1152/japplphysiol.00392.2020.

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We found using wireless near-infrared spectroscopy that prefrontal oxygenation increased before the onset of arbitrary over-ground walking, whereas the preexercise increase was absent when walking was suddenly started by cue. The difference in prefrontal oxygenation between start modes (considered related to central command) preceded heart rate response variances and demonstrated a positive relationship with the difference in heart rate. The central command-related prefrontal activity may contribute to cardiac adjustment, synchronized with the beginning of over-ground walking.
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24

Llamas-Ramos, Rocío, Juan Luis Sánchez-González, Jorge Juan Alvarado-Omenat, Ismael Sanz-Esteban, J. Ignacio Serrano, and Inés Llamas-Ramos. "fNIRS Feasibility to Measure Brain Oxygenation Patterns of the Motor Cortex in Relation to Massage and Reflex Locomotion Therapy in Babies." Journal of Clinical Medicine 14, no. 11 (2025): 3818. https://doi.org/10.3390/jcm14113818.

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Background: Newborns’ plasticity allows the brain to adapt and reorganize in response to external stimuli; therefore, tactile stimuli could generate brain changes. The objective of this study was to verify the feasibility of using fNIRS to measure the degree of brain oxygenation with tactile techniques in babies. Methods: Oxygenation was recorded continuously and bilaterally before, during, and after the interventions (massage protocol and Reflex Locomotion Therapy) with functional near-infrared spectroscopy in 11-week-old babies. Results: Preliminary data suggested that the massage interventi
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25

McArthur, James G., Thiago Maciel, Chunsheng Chen, et al. "A Novel, Highly Potent and Selective PDE9 Inhibitor for the Treatment of Sickle Cell Disease." Blood 128, no. 22 (2016): 268. http://dx.doi.org/10.1182/blood.v128.22.268.268.

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Abstract Background Hydroxyurea (HU), a chemotherapeutic agent and an approved therapy for sickle cell disease (SCD), increases cGMP levels and thereby increases fetal hemoglobin (HbF) levels in RBC, which generally correlates with decreased hemolysis and reduced disease severity in subjects with SCD. In addition, increased cGMP levels are anti-inflammatory and reduce the adhesion of WBC to the vascular endothelium. However, potential adverse effects of HU such as infertility, susceptibility to infections, or teratogenic effect have been the subject of concerns. Phosphodiesterase-9 inhibitors
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26

Vitória Cajé Moura, Luna, Rhalliete Souza Cruz, Laryssa Ramos Fraga Pedreira, and Aline Henri Motta Coifman. "PLANO DE CUIDADOS DE ENFERMAGEM A PACIENTES ADMITIDOS COM SEPSE EM UNIDADE DE TERAPIA INTENSIVA." Revista Brasileira de Saúde Funcional 7, no. 1 (2019): 145. http://dx.doi.org/10.25194/rebrasf.v7i1.1191.

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Introdução: A sepse se configura como fator agravante da morbidade de pacientes críticos. Sua detecção precoce e manejo clínico eficaz são contribuintes para melhora de prognóstico e diminuição da permanência destes pacientes em hospitais. Objetivo: Apresentar um plano de cuidados de enfermagem, à luz da teoria das Necessidades Humanas Básicas (NHB) e da Taxonomia II da North American Nursing Diagnosis Association (NANDA) a pacientes admitidos com sepse em Unidade de Terapia Intensiva (UTI) de um hospital privado em Salvador-BA. Metodologia: estudo qualitativo, cuja coleta de dados foi realiza
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27

Paredes-Ruiz, María-José, María Jodar-Reverte, Inés Albertus-Cámara, Ignacio Martínez González-Moro, and Vicente Ferrer-Lopez. "Sport Mont 2023, 21(1), 9-15 | DOI: 10.26773/smj.230202 Abstract The military parachutists are responsible of special air operations who require certain capabilities in their physical condition, due to their intense professional career. The analysis of oxygen con-sumption (VO2) and heart rate (HR) allows the determination of aerobic (VT1) and anaerobic (VT2) thresholds and used to study the adequacy of the organism to exercise and in the analysis of sporting performance. The aim of this study was to determine the effect of tactical equipment on the stress test performance of elite parachutists. 10 parachutists parti-cipated in the study, between 22 and 36 years old with an average of 27.75 years (±4.20). Anthropometric values were determined of: weight 75.69 kg (±8.79), height 173.34 cm (±5.72) and body mass index (BMI) 25.23 (±2.98). Each one, performed 2 maximal treadmill exercise testing: one a conventional stress test (A) and another with the tactical equipment (weight 20 kg) (B). We obtained maximum oxygen consumption (Metalyzer 3B) and monitored the electrocardiogram continuously. The test started at a speed of 6km/h and a slope of 1%. The results of the two test were compared. The average value and standard deviation (SD) of different variables with equipment (B) and without it (A) and p-value were obtained: velocity (A: 14.80±3.29; B: 11.50±1.42 Km/h; p=0.073), HR (A: 182.7±58.62; B: 177.75±9.71 b/m; p=0.038), VO2 (A: 51.75±13.60; B: 54.00±30.82 ml/Kg/min; p=0.891). Al-so, the values of ventilatory thresholds: VT1 and VT2 of both tests were obtained, with sig-nificant differences. Tactical equipment causes a decrease in stress test performance with changes in VT1 and VT2. 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Match running performance of elite soccer players: VO2max and players position influences. The Journal of Strength & Conditioning Research, 35(1), 162-168. Mina-Paz, Y., Tafur-Tascón, L.J., Cabrera-Hernández, M.A., Povea-Combariza, C., Tejada-Rojas, C.X., Hurtado-Gutiérrez, H. & Garcia-Vallejo, F. (2021). Ventilatory threshold concordance between ergoespirometry and heart rate variability in female professional cyclists. Revista de Deporte Humano y Ejercicio, 18(1), 1-10. Mouine, N., Parada, T., Amah, G., Gagey, S., Guity, C., Duval, M. & Abdennbi, K. (2021). Pre-diction of peak oxygen consumption by incremental 6 minutes walking test in patients with Ischemic heart disease after cardiac rehabilitation. Archives of Cardiovascular Diseases Supplements, 13(1), 119. Paredes-Ruiz, M.J., Jódar-Reverte, M., Ferrer-López, V., & Martínez-González-Moro, I. (2021). Muscle oxygenation of the quadriceps and gastrocnemius during maximal aerobic effort. Revista Brasileira de Medicina do Esporte, 27, 212-217. Paredes-Ruiz, M.J., Jódar-Reverte, M., Martínez-González-Moro, I., & Ferrer-López, V. (2021). Effects of gender on oxygen saturation of thigh muscles during maximal treadmill exercise testing. Sport Mont, 19(1), 7-11. Perlsweig, K.A., Abt, J.P., Nagai, T., Sell, T.C., Wirt, M.D., & Lephart, S.M. (2015). Effects of age and military service on strength and physiological characteristics of US army soldiers. Medicine and Science in Sports and Exercise, 47(5), 420. Pihlainen, K.A.I., Santtila, M., Häkkinen, K., & Kyröläinen, H. (2018). Associations of physical fitness and body composition characteristics with simulated military task performance. The Journal of Strength & Conditioning Research, 32(4), 1089-1098. Pollock, M.L., Bohannon, R.L., Cooper, K.H., Ayres, J.J., Ward, A., White, S.R., & Linnerud, A.C. (1976). A comparative analysis of four protocols for maximal treadmill stress testing. American Heart Journal, 92(1), 39-46. Riboli, A., Coratella, G., Rampichini, S., Limonta, E., & Esposito, F. (2022). Testing protocol affects the velocity at VO2max in semi-professional soccer players. Research in Sports Medicine, 30(2), 182-192. Ronconi, M., & Alvero-Cruz, J.R. (2011). Respuesta de la frecuencia cardiaca y consumo de oxígeno de atletas varones en competiciones de duatlón sprint. Apunts Sports Medicine, 46(172), 183-188. Rosenblat, M.A., Granata, C., & Thomas, S.G. (2022). Effect of interval training on the factors influencing maximal oxygen consumption: A systematic review and meta-analysis. Sports Medicine, 1-24. Silva, M.J.S., Rabelo, A.S., Vale, R.G.S., Ferrão, M.L.D., Sarmiento, L., & Dantas, E.H.M. (2009) Correlation between VO2 max, relative fatness and lipid profile in cadets of the Military Police Academy of the State of Rio de Janeiro. European Journal of Human Movement, 22, 147-157. Stavrou, V.T., Tourlakopoulos, K.N, Daniil, Z., & Gourgoulianis, K. I. (2021). Hypoxia re-sistance comparing between physically trained pilots and non-trained population. Cureo, 13(5), 1-6. Taylor, M.K., Hernández, L.M., Schoenherr, M.R., & Stump, J. (2019). Genetic, physiologic, and behavioral predictors of cardiorespiratory fitness in specialized military men. Military Medicine, 184(9), 474-481. WHO (1st february 2022). Obesity and overweight. https://www.who.int/es/news-room/fact-sheets/detail/obesity-and-overweight. https://doi.org/10.26773/smj.230202 APA citation Paredes-Ruiz, M., Jodar-Reverte, M., Albertus-Cámara, I., González-Moro, I. M., & Ferrer-Lopez, V. (2023). Influence of Tactical Equipment on the Ergospirometric Assessment of Military Parachutists. Sport Mont, 21(1),9-15. doi: 10.26773/smj.230202 MLA8 citation Chicago citation This page has been visited 32 times This article has been downloaded 3 times." Sport Mont 21, no. 1 (2023): 9–15. http://dx.doi.org/10.26773/smj.230202.

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The military parachutists are responsible of special air operations who require certain capabilities in their physical condition, due to their intense professional career. The analysis of oxygen con-sumption (VO2) and heart rate (HR) allows the determination of aerobic (VT1) and anaerobic (VT2) thresholds and used to study the adequacy of the organism to exercise and in the analysis of sporting performance. The aim of this study was to determine the effect of tactical equipment on the stress test performance of elite parachutists. 10 parachutists parti-cipated in the study, between 22 and 36 y
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Iannetta, Danilo, Joshua C. Weavil, Fabio Giuseppe Laginestra, et al. "Control of hyperpnoea and pulmonary gas exchange during prolonged exercise: The role of group III/IV muscle afferent feedback." Journal of Physiology, September 24, 2024. http://dx.doi.org/10.1113/jp286993.

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AbstractIt remains unclear whether feedback from group III/IV muscle afferents is of continuous significance for regulating the pulmonary response during prolonged (>5 min), steady‐state exercise. To elucidate the influence of these sensory neurons on hyperpnoea, gas exchange efficiency, arterial oxygenation and acid–base balance during prolonged locomotor exercise, 13 healthy participants (4 females; 21 (3) years, : 46 (8) ml/kg/min) performed consecutive constant‐load cycling bouts at ∼50% (20 min), ∼75% (20 min) and ∼100% (5 min) of with intact (CTRL) and pharmacologically attenuated (lu
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Espinosa-Ramírez, Maximiliano, Eduardo Moya-Gallardo, Felipe Araya-Román, et al. "Sex-Differences in the Oxygenation Levels of Intercostal and Vastus Lateralis Muscles During Incremental Exercise." Frontiers in Physiology 12 (October 1, 2021). http://dx.doi.org/10.3389/fphys.2021.738063.

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This study aimed to examine sex differences in oxygen saturation in respiratory (SmO2-m.intercostales) and locomotor muscles (SmO2-m.vastus lateralis) while performing physical exercise. Twenty-five (12 women) healthy and physically active participants were evaluated during an incremental test with a cycle ergometer, while ventilatory variables [lung ventilation (V.E), tidal volume (Vt), and respiratory rate (RR)] were acquired through the breath-by-breath method. SmO2 was acquired using the MOXY® devices on the m.intercostales and m.vastus lateralis. A two-way ANOVA (sex × time) indicated tha
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Iannetta, Danilo, Joshua Weavil, Taylor Thurston, et al. "On the significance of group III/IV muscle afferent feedback for the control of breathing and gas exchange efficiency during prolonged locomotor exercise." Physiology 38, S1 (2023). http://dx.doi.org/10.1152/physiol.2023.38.s1.5734420.

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Introduction: By projecting to medullary respiratory center, group III/IV muscle afferents determine the ventilatory response during short (~3 min) bouts of locomotor exercise. However, their significance for the hyperpneic response, gas exchange efficiency, and arterial oxygenation during exercise of longer durations (>15min) remains unknown. Methods: On 2 separate days, 8 healthy subjects (22±3yrs, 4 f) performed two 20-min bicycling bouts at 30% (~50% V̇O2max) and 50% (~75% V̇O2max) of peak power (Wpeak) under a) control condition (intact leg muscle afferent feedback; CTRL), and b) lumba
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Ohya, Toshiyuki, Masahiro Hagiwara, and Yasuhiro Suzuki. "Inspiratory muscle warm-up has no impact on performance or locomotor muscle oxygenation during high-intensity intermittent sprint cycling exercise." SpringerPlus 4, no. 1 (2015). http://dx.doi.org/10.1186/s40064-015-1355-2.

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32

Murray, Donal, Randall E. Keyser, Lisa M. K. Chin, Thomas C. Bulea, Clinton J. Wutzke, and Andrew A. Guccione. "EMG median frequency shifts without change in muscle oxygenation following novel locomotor training in individuals with incomplete spinal cord injury." Disability and Rehabilitation, April 24, 2020, 1–7. http://dx.doi.org/10.1080/09638288.2020.1755729.

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33

Tran, Zinnia, Sakthijothi Muthu, Kate Karelina, Kienan ODwyer, Subhankhi Pal, and Venkatesh Sundararajan. "Abstract Tu044: Cardiac Mitochondrial Dysfunction Induces Region-Specific Mitochondrial Stress Response In The Brain To Adapt Neuronal Changes." Circulation Research 135, Suppl_1 (2024). http://dx.doi.org/10.1161/res.135.suppl_1.tu044.

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Background: The hippocampus and cortex are susceptible to changes in blood supply, metabolites, and oxygenation. However, how disrupted cardiac function affects these critical areas of the brain, leading to the cognitive and neurological consequences of heart failure, remains unclear. Hypothesis: We hypothesize that disrupted cardiac function cross-talks with the brain by inducing region-specific mitochondrial stress responses, leading to adaptive changes. Methods: We utilized cardiac-specific LonP1 knockout (LonP1cKO) mice to induce heart failure within 21 days of birth. Alongside cre- contro
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Gabler, Mikaela C., Bruce J. Martin, Blair D. Johnson, Zachary J. Schlader, and Robert F. Chapman. "Inspiratory Muscle Warm-Up and Perceptual, Physiological, and Performance Outcomes During Exercise in Normoxia and Hypoxia." International Journal of Sports Physiology and Performance, 2025, 1–9. https://doi.org/10.1123/ijspp.2024-0425.

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Introduction: Some evidence shows that an inspiratory muscle warm-up (IMW) could enhance exercise performance; however, outcomes are mixed, and the mechanistic basis is unclear. Therefore, our purpose was to examine how IMW affects the sensory and affective components of dyspnea, exercise performance, and locomotor muscle oxygenation. Methods: Thirteen recreationally active individuals (23 [5] y, 5 women) performed a cycling time-to-exhaustion test (∼80%–85% maximal oxygen uptake) preceded by either IMW (2 × 30 breaths, 40% maximal inspiratory pressure) or SHAM (2 × 30 breaths, 15% maximal ins
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Duffy, Jennifer, Ryan Hoiland, Oliver Wearing, Erin Erskine, Brian Kwon, and Christopher West. "Cardio-centric hemodynamic management with and without adjuvant ethyl nitrite improves mean arterial pressure in rodents with chronic high-thoracic traumatic spinal cord injury." Physiology 38, S1 (2023). http://dx.doi.org/10.1152/physiol.2023.38.s1.5734885.

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Objective: Traumatic spinal cord injury (SCI) causes an initial injury followed by a protracted phase of spinal cord tissue hypoxia. This tissue hypoxia contributes to secondary injury, leading to worse motor and cardio-autonomic outcomes in the chronic setting. No neuroprotective agents to mitigate secondary injury have been identified as efficacious in clinical trials. However, we have demonstrated that taking a cardio-centric approach to hemodynamic management following SCI by augmenting cardiac output and mean arterial pressure (MAP) with the b1-adrenoceptor agonist dobutamine (DOB), and f
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Bourgeois, Hubert, Penelope Paradis, and François Billaut. "High-intensity interval training with blood-flow restriction enhances sprint and maximal aerobic power in male endurance athletes." Applied Physiology, Nutrition, and Metabolism, December 6, 2024. https://doi.org/10.1139/apnm-2024-0378.

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High-intensity interval training (HIIT) can improve endurance performance. Purpose: We investigated the concurrent impact of HIIT and blood-flow restriction (BFR) as a novel approach to further enhance maximal aerobic and anaerobic physiology and performances in trained athletes. Methods: In a randomized controlled trial, eighteen endurance-trained males (V ̇O2peak 65.6±5.1 ml.min-1.kg-1) included three sessions of HIIT per week (sets of 15-s efforts at 100% maximal aerobic power, interspersed by 15-s recovery) into their usual training for three weeks, either with restriction imposed on both
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Gabler, Mikaela, Bruce Martin, Blair Johnson, Zachary Schlader, and Robert Chapman. "Effects of inspiratory muscle warm-up on perceptual, physiological, and performance outcomes during high-intensity exercise in normoxia and hypoxia." Physiology 39, S1 (2024). http://dx.doi.org/10.1152/physiol.2024.39.s1.521.

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Some evidence shows that an inspiratory muscle warm-up (IMW) could enhance exercise performance; however, the mechanistic basis is unclear. PURPOSE: To examine how IMW affects the sensory and affective components of dyspnea, exercise performance, and locomotor muscle oxygenation. METHODS: Thirteen recreationally active individuals (23 ± 5 yr, 5 women) performed a cycling time to exhaustion test (~80-85% VȮ2max) preceded by either IMW (2x30 breaths, 40% maximal inspiratory pressure) or SHAM (2x30 breaths, 15% maximal inspiratory pressure) in normoxic (FIO2 = 0.21) and hypoxic (FIO2 = 0.16) cond
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Zhang, Qingguang, Morgane Roche, Kyle W. Gheres, et al. "Cerebral oxygenation during locomotion is modulated by respiration." Nature Communications 10, no. 1 (2019). http://dx.doi.org/10.1038/s41467-019-13523-5.

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AbstractIn the brain, increased neural activity is correlated with increases of cerebral blood flow and tissue oxygenation. However, how cerebral oxygen dynamics are controlled in the behaving animal remains unclear. We investigated to what extent cerebral oxygenation varies during locomotion. We measured oxygen levels in the cortex of awake, head-fixed mice during locomotion using polarography, spectroscopy, and two-photon phosphorescence lifetime measurements of oxygen sensors. We find that locomotion significantly and globally increases cerebral oxygenation, specifically in areas involved i
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De Martino, Fabiana, Irene Mattavelli, Carlo Vignati, et al. "393 PERIODIC BREATHING: WHAT HAPPENS IN THE MUSCLE?" European Heart Journal Supplements 24, Supplement_K (2022). http://dx.doi.org/10.1093/eurheartjsupp/suac121.451.

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Abstract Periodic breathing (PB) is a recognized sign of poor prognosis in heart failure (HF). It is defined as a cyclic fluctuation of minute ventilation, and oxygen uptake (V̇O2) and carbon dioxide elimination (V̇CO2) at the lungs. It is unknow whether PB influences O2 availability in the cardiac, respiratory and locomotor muscles. To evaluate whether O2 availability at the muscles was affected by PB, we measured at rest, continuously and simultaneously, ventilation, ventilatory gas exchange, arterial hemoglobin O2 saturation and oxygenated/deoxygenated haemoglobin (O2Hb/HHb) content over th
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Weibley, Hannah, Mina Di Filippo, Xinran Liu, et al. "fNIRS Monitoring of Infant Prefrontal Cortex During Crawling and an Executive Functioning Task." Frontiers in Behavioral Neuroscience 15 (August 13, 2021). http://dx.doi.org/10.3389/fnbeh.2021.675366.

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Functional near-infrared spectroscopy (fNIRS)is a brain-imaging technology used to reveal brain activity by measuring blood oxygenation. Using fNIRS we measured activity in the left prefrontal lobe of 8–14 month-old infants as they crawled or were pushed in a stroller and as they were given a passive attention task or an active executive function (EF) task. For each task, we measured peak total hemoglobin concentration and peak Oxy relative to baseline. Results revealed differences in peak Oxy levels for crawling vs. strolling and between the EF and passive cognitive tasks, with total hemoglob
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Llamas-Ramos, Rocío, Juan Luis Sánchez-González, Jorge Juan Alvarado-Omenat, Vicente Rodríguez-Pérez, and Inés Llamas-Ramos. "Brain electrical activity and oxygenation by Reflex Locomotion Therapy and massage in preterm and term infants. A protocol study." NeuroImage, July 2024. http://dx.doi.org/10.1016/j.neuroimage.2024.120765.

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42

Hernandez-Charpak, Sergio Daniel, Nawal Kinany, Ilaria Ricchi, et al. "Towards Personalized Mapping Through Lumbosacral Spinal Cord Task fMRI." Imaging Neuroscience, 2025. https://doi.org/10.1162/imag_a_00455.

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Abstract The lumbosacral spinal cord contains neural circuits crucial for locomotion, organized into rostrocaudal levels with distinct somatosensory and motor neuron pools that project to and from the muscles of the lower limbs. However, the specific spinal levels that innervate each muscle and the locations of neuron pools vary significantly between individuals, presenting challenges for targeted therapies and neurosurgical interventions aimed at restoring locomotion. Non-invasive approaches to functionally map the segmental distribution of muscle innervation – or projectome – are therefore e
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Silva, Kenya Lima, and Maria Miriam Lima Da Nóbrega. "Collection of data for children of 0 - 5 years: construction and validation of an instrument." Online Brazilian Journal of Nursing 5, no. 3 (2006). http://dx.doi.org/10.17665/1676-4285.2006704.

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Study of the methodological type that had as objective to construct and to validate of an instrument of collection of data for children of 0 the 5 years taken care of in the Pediatrics Clinic of the University Hospital Lauro Wanderley and to test the operacionalition of the instrument with children of the Pediatrics Clinic. The same it was I base in the Theory of the Needs Basic Human of Horta. For the construction of the instrument, it was used specialized literature of the area of pediatrics nursing and pediatrics, for the identification of the manifestations of the needs basic human more fr
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Mendelson, Asher A., Dustin Erickson, and Rodrigo Villar. "The role of the microcirculation and integrative cardiovascular physiology in the pathogenesis of ICU-acquired weakness." Frontiers in Physiology 14 (May 10, 2023). http://dx.doi.org/10.3389/fphys.2023.1170429.

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Skeletal muscle dysfunction after critical illness, defined as ICU-acquired weakness (ICU-AW), is a complex and multifactorial syndrome that contributes significantly to long-term morbidity and reduced quality of life for ICU survivors and caregivers. Historically, research in this field has focused on pathological changes within the muscle itself, without much consideration for their in vivo physiological environment. Skeletal muscle has the widest range of oxygen metabolism of any organ, and regulation of oxygen supply with tissue demand is a fundamental requirement for locomotion and muscle
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45

Zhang, Qingguang, Hannah C. Bennett, Yuan-ting Wu, et al. "Abstract 12907: Aging Drives Cerebrovascular Network Remodeling and Functional Changes in the Mouse Brain." Circulation 148, Suppl_1 (2023). http://dx.doi.org/10.1161/circ.148.suppl_1.12907.

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Introduction: Cerebrovascular dysfunction has been implicated in age-related cognitive decline and dementia, but the underlying vascular mechanisms are not well understood. An improved understanding of the nature of normal cerebrovascular aging is needed to help to establish the role that vascular dysfunction might play in cognitive decline and dementia. Methods: Here, we asked how normal aging differentially impacts the vascular structure and function in different brain areas in mice. We investigated structural changes in aged cerebrovascular networks and pericytes utilizing serial two-photon
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