Relevant bibliographies by topics / Long non-coding Heg RNA

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Long non-coding Heg RNA'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Long non-coding Heg RNA"

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Christensen, Niels. "Regulation of TSH Receptor Autoantibodies by a long Non-Coding RNA (Heg) and Cdk1- A Review." British Journal of Medicine and Medical Research 3, no. 3 (2013): 508–16. http://dx.doi.org/10.9734/bjmmr/2013/2616.

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Wang, Danni, Danbo Wang, Ning Wang, Zaiqiu Long, and Xuemei Ren. "Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway." Cellular Physiology and Biochemistry 40, no. 3-4 (2016): 644–56. http://dx.doi.org/10.1159/000452577.

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Background/Aims: Microarray screening had found BRAF-activated non-coding RNA (BANCR) was significantly upregulated in type 1 endometrial cancer (EC). This study aimed to assess the potential role of long non-coding RNA (lncRNA) BANCR in the pathogenesis and progression of type 1 EC. Methods: Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was used to confirm the expression of BANCR in type 1 EC tissue, and analyze its clinical significance. In vitro, RNA interference (siRNA) was used to investigate the biological role of BANCR in type 1 EC. Results: qRT-PCR revealed tha
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Haque, Sulsal-Ul, Liang Niu, Damaris Kuhnell, et al. "Differential expression and prognostic value of long non-coding RNA in HPV-negative head and neck squamous cell carcinoma." Head & Neck 40, no. 7 (2018): 1555–64. http://dx.doi.org/10.1002/hed.25136.

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Mitsuhashi, Satomi, So Nakagawa, Mitsuru Sasaki-Honda, Hidetoshi Sakurai, Martin C. Frith, and Hiroaki Mitsuhashi. "Nanopore direct RNA sequencing detects DUX4-activated repeats and isoforms in human muscle cells." Human Molecular Genetics 30, no. 7 (2021): 552–63. http://dx.doi.org/10.1093/hmg/ddab063.

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Abstract Facioscapulohumeral muscular dystrophy (FSHD) is an inherited muscle disease caused by misexpression of the DUX4 gene in skeletal muscle. DUX4 is a transcription factor, which is normally expressed in the cleavage-stage embryo and regulates gene expression involved in early embryonic development. Recent studies revealed that DUX4 also activates the transcription of repetitive elements such as endogenous retroviruses (ERVs), mammalian apparent long terminal repeat (LTR)-retrotransposons and pericentromeric satellite repeats (Human Satellite II). DUX4-bound ERV sequences also create alt
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Lezirovitz, Karina, Gleiciele A. Vieira-Silva, Ana C. Batissoco, et al. "A rare genomic duplication in 2p14 underlies autosomal dominant hearing loss DFNA58." Human Molecular Genetics 29, no. 9 (2020): 1520–36. http://dx.doi.org/10.1093/hmg/ddaa075.

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Abstract Here we define a ~200 Kb genomic duplication in 2p14 as the genetic signature that segregates with postlingual progressive sensorineural autosomal dominant hearing loss (HL) in 20 affected individuals from the DFNA58 family, first reported in 2009. The duplication includes two entire genes, PLEK and CNRIP1, and the first exon of PPP3R1 (protein coding), in addition to four uncharacterized long non-coding (lnc) RNA genes and part of a novel protein-coding gene. Quantitative analysis of mRNA expression in blood samples revealed selective overexpression of CNRIP1 and of two lncRNA genes
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Cardoso, Ana M., Catarina M. Morais, Olinda Rebelo, et al. "Downregulation of long non-protein coding RNA MVIH impairs glioblastoma cell proliferation and invasion through an miR-302a-dependent mechanism." Human Molecular Genetics 30, no. 1 (2021): 46–64. http://dx.doi.org/10.1093/hmg/ddab009.

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Abstract Glioblastoma (GB) is the most frequent and malignant type of brain tumor, for which no effective therapy exists. The high proliferative and invasive nature of GB, as well as its acquired resistance to chemotherapy, makes this type of cancer extremely lethal shortly after diagnosis. Long non-protein coding RNAs (lncRNA) are a class of regulatory RNAs whose levels can be dysregulated in the context of diseases, unbalancing several physiological processes. The lncRNA associated with microvascular invasion in hepatocellular carcinoma (lncRNA-MVIH), overexpressed in several cancers, was de
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Treeck, Oliver, Florian Weber, Juergen Fritsch, et al. "DSCAM-AS1 Long Non-Coding RNA Exerts Oncogenic Functions in Endometrial Adenocarcinoma via Activation of a Tumor-Promoting Transcriptome Profile." Biomedicines 10, no. 7 (2022): 1727. http://dx.doi.org/10.3390/biomedicines10071727.

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Accumulating evidence suggests that lncRNA DSCAM-AS1 acts tumor-promoting in various cancer entities. In breast cancer, DSCAM-AS1 was shown to be the lncRNA being most responsive to induction by estrogen receptor α (ERα). In this study, we examined the function of DSCAM-AS1 in endometrial adenocarcinoma using in silico and different in vitro approaches. Initial analysis of open-source data revealed DSCAM-AS1 overexpression in endometrial cancer (EC) (p < 0.01) and a significant association with shorter overall survival of EC patients (HR = 1.78, p < 0.01). In EC, DSCAM-AS1 was associated
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Cardamone, Giulia, Elvezia M. Paraboschi, Giulia Soldà, et al. "Not only cancer: the long non-coding RNA MALAT1 affects the repertoire of alternatively spliced transcripts and circular RNAs in multiple sclerosis." Human Molecular Genetics 28, no. 9 (2018): 1414–28. http://dx.doi.org/10.1093/hmg/ddy438.

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AbstractLong non-coding RNAs (lncRNAs) are post-transcriptional and epigenetic regulators, whose implication in neurodegenerative and autoimmune diseases remains poorly understood. We analyzed publicly available microarray data sets to identify dysregulated lncRNAs in multiple sclerosis (MS), a neuroinflammatory autoimmune disease. We found a consistent upregulation in MS of the lncRNA MALAT1 (2.7-fold increase; meta-analysis, P = 1.3 × 10−8; 190 cases, 182 controls), known to regulate alternative splicing (AS). We confirmed MALAT1 upregulation in two independent MS cohorts (1.5-fold increase;
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Schmitt, Heather M., William M. Johnson, Inas F. Aboobakar, et al. "Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1." Human Molecular Genetics 29, no. 12 (2020): 1986–95. http://dx.doi.org/10.1093/hmg/ddaa021.

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Abstract Individuals with pseudoexfoliation (PEX) syndrome exhibit various connective tissue pathologies associated with dysregulated extracellular matrix homeostasis. PEX glaucoma is a common, aggressive form of open-angle glaucoma resulting from the deposition of fibrillary material in the conventional outflow pathway. However, the molecular mechanisms that drive pathogenesis and genetic risk remain poorly understood. PEX glaucoma-associated single-nucleotide polymorphisms are located in and affect activity of the promoter of LOXL1-AS1, a long non-coding RNA (lncRNA). Nuclear and non-nuclear
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Bjeije, Hassan, Bahram Mohammad Soltani, Mehrdad Behmanesh, and Mohammad Reza Zali. "YWHAE long non-coding RNA competes with miR-323a-3p and miR-532-5p through activating K-Ras/Erk1/2 and PI3K/Akt signaling pathways in HCT116 cells." Human Molecular Genetics 28, no. 19 (2019): 3219–31. http://dx.doi.org/10.1093/hmg/ddz146.

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AbstractYWHAE gene product belongs to the 14-3-3 protein family that mediates signal transduction in plants and mammals. Protein-coding and non-coding RNA (lncRNA) transcripts have been reported for this gene in human. Here, we aimed to functionally characterize YWHAE-encoded lncRNA in colorectal cancer-originated cells. RNA-seq analysis showed that YWHAE gene is upregulated in colorectal cancer specimens. Additionally, bioinformatics analysis suggested that YWHAE lncRNA sponges miR-323a-3p and miR-532-5p that were predicted to target K-Ras 3′UTR sequence. Overexpression of YWHAE lncRNA result
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Dissertations / Theses on the topic "Long non-coding Heg RNA"

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Ozes, Ali Rayet. "Targeting the long non coding RNA HOTAIR in cancer." Thesis, Indiana University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10154781.

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<p> Ovarian cancer (OC) takes the lives of nearly 14,000 US women every year. Although platinum is one of the most effective drugs in treating ovarian cancer, the development of platinum resistance is one of the biggest challenges facing patients. I have shown that the long non-coding RNA HOTAIR contributes to platinum-resistant OC and determined the regulators and targets of HOTAIR during the platinum-induced DNA damage response. My published data supports the role of HOTAIR in contributing to DNA damage induced cellular senescence and secretion of pro-inflammatory cytokines leading to cispla
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Ard, Ryan Anthony. "Functional long non-coding RNA transcription in Schizosaccharomyces pombe." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/20396.

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Eukaryotic genomes are pervasively transcribed and frequently generate long noncoding RNAs (lncRNAs). However, most lncRNAs remain uncharacterized. In this work, a set of positionally conserved intergenic lncRNAs in the fission yeast Schizosaccharomyces pombe genome are selected for further analysis. Deleting one of these lncRNA genes (ncRNA.1343) exhibited a clear phenotype: increased drug sensitivity. Further analyses revealed that deleting ncRNA.1343 also disrupted a previously unannotated lncRNA, termed nc-tgp1, transcribed in the opposite orientation of the predicted ncRNA.1343 gene and i
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Wijesinghe, Susanne. "Role of long non-coding RNA CCDC26 in gene regulation." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8441/.

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LncRNAs are increasingly being recognised as functionally important for regulation of biological processes. We have identified an lncRNA which we believe is integral in lineage commitment during haematopoiesis. Here, we report that CCDC26 lncRNA is a regulator of β-globin and c-MYC gene expression. Indeed, CCDC26 silencing in erythroleukemic K562 cells led to several gene expression changes. Upon further investigation of genes linked to erythropoiesis, we observed the upregulation of β-globin expression. Our results suggest that CCDC26 regulates expression of β-globin and other genes by modula
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Ottway, Charlotte Jane. "Characterisation of Nespas, a non-coding imprinted RNA." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:b159c1e9-8d49-460c-a808-d920e8e17779.

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Nespas is the non-coding antisense transcript of the imprinted Gnas cluster; it is expressed from the paternal allele and is located on mouse distal chromosome 2. In this thesis new transcripts of >10 kb and 0.8 kb have been identified. The 0.8 kb transcript is a spliced variant that is retained in the nucleus and its 3’ end lies approximately 30 kb from the start site. Transcription from the Nespas promoter does not proceed beyond this point. A collection of previously known splice variants have also been detected and are exported to the cytoplasm. Nespas is expressed in the embryo during the
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Cabili, Nataly Moran. "Integrative Characterization of Human Long Non-Coding RNAs." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11409.

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Since its early discovery as a messenger, RNA has been shown to play a diverse set of regulatory, structural and even catalytic roles. The more recent understanding that the genome is pervasively transcribed stimulated the discovery of a new prevalent class of long non coding RNAs (lncRNAs). While these are lower abundant and relatively less conserved than other class of functional RNAs, lncRNAs are emerging as key players in different cellular processes in development and disease.
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Hammel, Alexander John. "Evolutionary conservation of long intergenic non-coding RNA genes in Arabidopsis." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44974.

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Keniry, Andrew James. "H19 and miR-675 : a long noncoding RNA conceals a growth suppressing microRNA." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609990.

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Broadbent, Kate Mariel. "The regulatory capacity of long non-coding RNA in Plasmodium falciparum malaria." Thesis, Harvard University, 2014. http://nrs.harvard.edu/urn-3:HUL.InstRepos:13065005.

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The mechanisms underpinning gene regulation in P. falciparum malaria remain largely elusive, though mounting evidence suggests a major role for epigenetic feedback. Interestingly, long non-(protein)-coding RNAs (lncRNAs) have been found to play a dominant role in initiating and guiding the transcriptional, epigenetic, and post-transcriptional status of specific loci across a broad range of organisms. LncRNAs are uniquely poised to act co-transcriptionally on neighboring loci, and/or to remain physically tethered at their site of origin, and through sequence-specific binding activities can impa
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Ballantyne, Margaret. "Understanding the role of long non-coding RNA (LncRNA) in vascular pathology." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8101/.

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Coronary heart disease is a major cause of morbidity and mortality in the Western society. In the case of severe atherosclerosis, percutaneous intervention and coronary bypass grafting remain the preferred form of surgical treatment. However, the patency of both these treatments is limited and several bypass grafts and stents fail due to neointimal formation and in stent restenosis attributable to the proliferation of VSMCs. The resultant luminal renarrowing may manifest clinically with the return of symptoms such as chest pain or shortness of breath and ultimately requires further surgical in
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Pettini, Tom. "The role of novel long non-coding RNAs in Hox gene regulation." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/the-role-of-novel-long-noncoding-rnas-in-hox-gene-regulation(c8e44900-3ac0-40be-8ec6-b50179381d17).html.

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Whole genome transcriptome analysis has revealed that a large proportion of the genome in higher metazoa is transcribed, yet only a small proportion of this transcription is protein-coding. One possible function of non-coding transcription is that it enables complex and diverse body plans to evolve through variation in deployment of a relatively common set of protein-coding genes. Functional studies suggest that long non-coding RNAs (lncRNAs) regulate gene expression via diverse mechanisms, operating in both cis and trans to activate or repress target genes. An emerging theme common to lncRNA
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Books on the topic "Long non-coding Heg RNA"

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Rao, M. R. S., ed. Long Non Coding RNA Biology. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5203-3.

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Long Non-coding RNA. Elsevier, 2018. http://dx.doi.org/10.1016/c2017-0-00163-5.

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Ugarkovic, Durdica. Long Non-Coding RNAs. Springer, 2011.

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Ugarkovic, Durdica. Long Non-Coding RNAs. Springer, 2013.

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Ugarkovic, Durdica. Long Non-Coding RNAs. Springer, 2011.

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Rao, M. R. S. Long Non Coding RNA Biology. Springer Singapore Pte. Limited, 2017.

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Rao, M. R. S. Long Non Coding RNA Biology. Springer, 2018.

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Morris, Kevin V. Long Non-Coding RNAs in Human Disease. Springer London, Limited, 2016.

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Morris, Kevin V. Long Non-coding RNAs in Human Disease. Springer, 2018.

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Morris, Kevin V. Long Non-coding RNAs in Human Disease. Springer, 2016.

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Book chapters on the topic "Long non-coding Heg RNA"

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Saw, Phei Er, and Erwei Song. "Non-coding RNA: Long Non-coding RNA (lncRNA)." In RNA Therapeutics in Human Diseases. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-96-3041-7_5.

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Gullerova, Monika. "Long Non-coding RNA." In Genomic Elements in Health, Disease and Evolution. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-3070-8_4.

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Zhang, Youyou, Yi Feng, Zhongyi Hu, et al. "Characterization of Long Noncoding RNA-Associated Proteins by RNA-Immunoprecipitation." In Long Non-Coding RNAs. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3378-5_3.

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Wu, Mengshi, Dan Peng, and Xiaomin Zhong. "Exploration of Circular RNA Interactomes by RNA Pull-Down Method." In Long Non-Coding RNAs. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1697-0_18.

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Lai, Lan-Tian, Zhenyu Meng, Fangwei Shao, and Li-Feng Zhang. "Simultaneous RNA–DNA FISH." In Long Non-Coding RNAs. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3378-5_11.

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Lai, Lan-Tian, Zhenyu Meng, Fangwei Shao, and Li-Feng Zhang. "Simultaneous RNA-DNA FISH." In Long Non-Coding RNAs. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1697-0_11.

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Wijesinghe, Susanne N., Mark A. Lindsay, and Simon W. Jones. "Long Non-coding RNAs in Rheumatology." In Long Noncoding RNA. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92034-0_4.

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Jiang, Junjie, Tianli Zhang, Yutian Pan, et al. "Characterization of Long Non-coding RNA Associated Proteins by RNA-Immunoprecipitation." In Long Non-Coding RNAs. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1697-0_3.

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Dhaliwal, Navroop K., and Jennifer A. Mitchell. "Nuclear RNA Isolation and Sequencing." In Long Non-Coding RNAs. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3378-5_7.

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Dhaliwal, Navroop K., and Jennifer A. Mitchell. "Nuclear RNA Isolation and Sequencing." In Long Non-Coding RNAs. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1697-0_8.

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Conference papers on the topic "Long non-coding Heg RNA"

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Manchon, Laurent, Audrey Vautrin, Jamal Tazi, Aude Garcel, and Noelie Campos. "Targeting Long Non-Coding RNA splicing by novel candidate drug." In 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2019. http://dx.doi.org/10.1109/bibm47256.2019.8982977.

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Chakrabortty, Sudipto K., Lisa Bedford, Hidefumi Uchiyama, et al. "Abstract 5686: Long RNA sequencing of human plasma exosomes reveals full coverage of diverse protein coding and long non coding RNA." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5686.

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Cristiano, Francesca, Pierangelo Veltri, Mattia Prosperi, and Giuseppe Tradigo. "On the identification of long non-coding RNAs from RNA-seq." In 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2016. http://dx.doi.org/10.1109/bibm.2016.7822675.

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Chiyomaru, Takeshi, Soichiro Yamamura, Shinichiro Fukuhara, et al. "Abstract 4374: Genistein suppresses prostate cancer regulating long non-coding RNA." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4374.

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Omura, J., K. Habbout, T. Shimauchi, et al. "Long Non-Coding RNA H19 Promotes Right Ventricular Failure in PAH." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2496.

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Al Mamun, Abdullah, and Ananda Mohan Mondal. "Long Non-coding RNA Based Cancer Classification using Deep Neural Networks." In BCB '19: 10th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics. ACM, 2019. http://dx.doi.org/10.1145/3307339.3343249.

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Pedrini, Fabiola, Fabian Rose, Nada Ekiaby, et al. "Oncogene-induced long non-coding RNA (lncRNA) signatures in liver cancer." In 40. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag, 2024. http://dx.doi.org/10.1055/s-0043-1777604.

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Chiquitto, Alisson G., Lucas Otavio L. Silva, Liliane S. Oliveira, Douglas S. Domingues, and Alexandre R. Paschoal. "Impact of sequencing technologies on long non-coding RNA computational identification." In 2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2022. http://dx.doi.org/10.1109/bibm55620.2022.9995443.

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Button, A. C., R. Z. Blumhagen, I. V. Yang, and D. A. Schwartz. "Long Non-coding RNA in IPF: Regulatory Players in Lung Fibrosis." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2583.

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O'Brien, Stephen J., Theodore Kalbfleisch, Sudhir Srivastava, Shesh Rai, and Susan Galandiuk. "Abstract 1817: Differential expression of long non-coding RNA in colon adenocarcinoma RNA-sequence data set." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1817.

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Reports on the topic "Long non-coding Heg RNA"

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Liao, Jianhua, Jingting Liu, Baoqing Liu, Chunyan Meng, and Peiwen Yuan. Effect of OIP5-AS1 on clinicopathological characteristics and prognosis of cancer patients: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.10.0118.

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Review question / Objective: According to recent studies, long non-coding RNA (lncRNAs) i.e., OPA-interacting protein 5 antisense RNA 1 (OIP5-AS1) has an important role in various carcinomas. However, its role in the cancer is contradictory. Therefore, we aimed to evaluate the link between OIP5-AS1 and cancer patients' clinicopathological characteristics and prognosis to better understand OIP5-AS1's role in cancer. Condition being studied: Reported studies have revealed that long non-coding RNA (lncRNAs) are considerably involved in crucial physiological events in several carcinomas, it can in
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Liu, Miao, Tihong Liang, Fengyan Wang, Hua Yang, Xu Ning, and Hong Sun. Prognostic value of long non-coding RNA PVT1 as a potential biomarker in osteosarcoma: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.9.0050.

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