Relevant bibliographies by topics / Loop diuretics drugs

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Academic literature on the topic 'Loop diuretics drugs'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Loop diuretics drugs"

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Gafurova, N. M., E. V. Shikh, and O. D. Ostroumova. "Current Clinical and Pharmacological Approaches to the Prescription of Loop Diuretics in Patients with Chronic Heart Failure." Rational Pharmacotherapy in Cardiology 16, no. 4 (2020): 595–600. http://dx.doi.org/10.20996/1819-6446-2020-03-04.

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Heart failure (HF) is a growing public health problem with an estimated prevalence of 38 million patients worldwide. Congestion and formation of edema – are typical symptoms of heart failure. Diuretics are the mainstay of therapy in heart failure and are used to relieve congestion and improve exercise tolerance. Also, the administration of diuretics should be considered to reduce the risk of HF hospitalization. Loop diuretics are used by nearly 80% of all chronic HF patients and remain the drugs of choice. Although diuretics are one of the most prescribed classes of drugs, recommendations for
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Nag, Dipankar Chandra, AKM Murshed, Rajashis Chakrabortty, and Md Raziur Rahman. "Mechanism and management of diuretic resistance in congestive heart failure." Journal of Dhaka National Medical College & Hospital 17, no. 1 (2012): 44–46. http://dx.doi.org/10.3329/jdnmch.v17i1.12193.

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Diuretic drugs are used almost universally in patients with congestive heart failure, most frequently the potent loop diuretics. Despite their unproven effect on survival, their indisputable efficacy in relieving congestive symptoms makes them first line therapy for most patients. In the treatment of more advanced stages of heart failure diuretics may fail to control salt and water retention despite the use of appropriate doses. Diuretic resistance may be caused by decreased renal function and reduced and delayed peak concentrations of loop diuretics in the tubular fluid, but it can also be ob
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Brunisholz, M. C., K. L. Lynn, and J. S. Hunt. "Loop-acting diuretics do not bind to Tamm–Horsfall urinary glycoprotein." Clinical Science 73, no. 3 (1987): 305–10. http://dx.doi.org/10.1042/cs0730305.

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1. Binding between the radiolabeled loop-acting diuretics ([14C]frusemide, [14C]ethacrynic acid and [3H]bumetanide) and human Tamm–Horsfall glycoprotein or human serum albumin in vitro was evaluated by equilibrium dialysis. 2. The diuretic action and binding to urinary Tamm–Horsfall glycoprotein of the radiolabeled diuretics in vivo, after intravenous administration, were examined in rabbits. 3. In vitro, all three radiolabeled diuretics bound strongly to human serum albumin, but not to Tamm–Horsfall glycoprotein. 4. Radiolabeled frusemide and bumetanide, but not ethacrynic acid, caused a diur
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4

Lazarev, P. O. "Loop diuretics – rules of appointment in congestive chronic heart failure." Medicine of Ukraine, no. 1(267) (February 13, 2023): 5–7. http://dx.doi.org/10.37987/1997-9894.2023.1(267).281391.

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The article is devoted to the use in everyday clinical practice of loop diuretics, which play a central role in the therapy of patients with congestive heart failure. When using drugs of this class, the correct dosage, regular monitoring of therapy, adequate prevention and measures to overcome resistance to loop diuretics are of primary importance.
 In order to obtain maximum efficiency and a high level of safety for the patient, the basic rules for the appointment and control of diuretic therapy should be strictly followed.
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Dyadyk, A. I., G. G. Taradin, Yu V. Suliman, S. R. Zborovskyy, and V. I. Merkuriev. "Diuretics in chronic kidney disease." Russian Archives of Internal Medicine 10, no. 1 (2020): 10–20. http://dx.doi.org/10.20514/2226-6704-2020-10-1-10-20.

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The issues of diuretic therapy in patients with chronic kidney disease, pharmacokinetics of diuretics, the problem of diuretic resistance, the tactics of using thiazides and loop diuretics in patients with various stages of chronic kidney disease, according to the recommendations of the National Kidney Foundation Kidney Disease Outcomes Quality Initiative are discussed in the article. Particular attention is paid to the prescription of this group of drugs to patients with end stage renal disease, as well as those undergoing renal replacement therapy (hemodialysis).Diuretics play an important r
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Tkachova, O. V., Ya O. Butko, and O. O. Gerasymova. "The Use of Diuretics in Medicine and Sports and the Monitoring of Their Consumption in Ukraine." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 7, no. 5 (2022): 152–57. http://dx.doi.org/10.26693/jmbs07.05.152.

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The purpose of the work was to study the range and volume of consumption of diuretics on the pharmaceutical market of Ukraine in 2019-2021. Materials and methods. Indications for the use of diuretics in medicine and sports, as well as the results of monitoring their consumption on the pharmaceutical market of Ukraine in the period from 2019 to 2021 are given in the article. The analysis of the range of diuretic drugs on the pharmaceutical market of Ukraine was carried out according to the information and search system “Pharmstandard” of the “Morion” company. Monitoring of the volume and struct
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Muralinath, .E., Devi Pooja, Chbukdhara Prasanta, et al. "Understanding Drugs Acting on the Urinary Tract." Journal of Trauma, Orthopaedic and Urological Nursing 2, no. 1 (2023): 1–6. https://doi.org/10.5281/zenodo.10217212.

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<i>The urinary tract plays a role in regulation of body's fluidvas well as electrolyte balance and an excretion of waste products. Diuretics enhance Urine production and enhance theme elimination of excess salt and where from the body. Diuretics also help regarding the treatment of conditions namely congestive heart failure CHF), edema and hypertension. Types of Diuretics include thiazide Diuretics, loop Diuretics and anti muscatinics. Anti-muscarinics such as interstitial cystitis and neurogenic bladder spams. It is finally concluded that Diuretics and antibiotics fight against infections and
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Bianco, S., MG Pieroni, RM Refini, M. Robuschi, A. Vaghi, and P. Sestini. "Inhaled loop diuretics as potential new anti-asthmatic drugs." European Respiratory Journal 6, no. 1 (1993): 130–34. http://dx.doi.org/10.1183/09031936.93.06010130.

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The observation that changes in bronchial osmolarity can induce bronchoconstriction in asthma inspired the experimental studies which, unexpectedly, revealed that frusemide is an effective bronchoprotective agent against a variety of osmotic and non osmotic stimuli. Although the mechanism of this protective effect is not fully understood, studies in vivo and in vitro suggest that frusemide may inhibit the activation of different cell types induced by bronchoconstrictor stimuli. Other loop diuretics also exert bronchoprotective activity, but frusemide appears to be the more effective bronchopro
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Patel, Varsha J., Paresh C. Parikh, and Chirag Vaghela. "Effect of diuretics on sodium, potassium and chloride levels- a cross sectional study." International Journal of Basic & Clinical Pharmacology 11, no. 6 (2022): 576. http://dx.doi.org/10.18203/2319-2003.ijbcp20222737.

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Background: Diuretics are one of the widely used class of drugs used in various cardiovascular and other disorders. However, they can cause various metabolic adverse effects, electrolyte imbalance being among important changes.Methods: A cross sectional study was conducted in which patients diagnosed with hypertension for at least one month were included. Over a period of 6 months patients were enrolled irrespective of whether they were taking diuretics or not. Demographic details, drug therapy and electrolyte levels were recorded in a proforma. Data was analyzed for difference in serum electr
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Palazzuoli, Alberto, Pietro Mazzeo, Martino Fortunato, et al. "The Changing Role of Loop Diuretics in Heart Failure Management across the Last Century." Journal of Clinical Medicine 13, no. 6 (2024): 1674. http://dx.doi.org/10.3390/jcm13061674.

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Congestion is the main therapeutic target of acute heart failure (HF) treatment, and loop diuretics (LDs) are widely used drugs for this purpose. Despite their extensive use, these agents remain largely understudied in terms of modality administration, treatment duration, and escalation dose for subjects responding poorly to therapy. LDs were initially investigated in several edematous statuses such as cirrhosis, nephrotic syndrome, and congestive HF and initially approved for the treatment of cardiogenic congestion in 1966. Despite the long history and the undoubted role in congestion managem
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Books on the topic "Loop diuretics drugs"

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Ellison, David H., and Arohan R. Subramanya. Clinical use of diuretics. Edited by Robert Unwin. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0033.

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Diuretics are widely employed to treat extracellular fluid volume expansion caused by heart failure, cirrhosis of the liver, nephrotic syndrome, and chronic kidney disease. Major classes of diuretic inhibit sodium reabsorption along the proximal tubule, the loop of Henle, the distal convoluted tubule, and the connecting and collecting tubules. Loop diuretics have the highest ceiling of action and often form the cornerstones of diuretic treatment of oedema. Members of this class are short-acting drugs, with different bioavailabilities, the specifics of which contribute importantly to a rational
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Krzesinski, Jean-Marie, and Eric P. Cohen. Approach to the patient with oedema. Edited by Robert Unwin. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0030_update_001.

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Generalized oedema reflects retention of salt and water that can be triggered by disease of several organs, but notably kidneys, heart and liver. Management is based on salt restriction and the use of diuretics. Diuretics have greatly improved its management, but in severe cases, ultrafiltration or dialysis may be needed for its treatment. In congestive heart failure, the nephrotic syndrome, or primary sodium retention, one proceeds rapidly, using mainly loop diuretics. Weight loss of 1 kg/day is a typical goal. Fluid removal in patients with cirrhosis and ascites, but without peripheral oedem
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Lameire, Norbert. Prevention of acute kidney injury. Edited by Norbert Lameire. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0226_update_001.

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This chapter summarizes the pharmacological interventions that can be used in the prevention of acute kidney injury (AKI). These following interventions are discussed: the use and selection of vasopressors; the administration of loop diuretics and mannitol; vasodilating drugs including dopamine, atrial natriuretic peptide, nesiritide, fenoldopam, and adenosine antagonists. The role of N-acetylcysteine in the prevention of contrast-induced AKI and cardiac surgery is discussed. The chapter concludes with a summary of the potential role of insulin-like growth factor and erythropoietin in the prev
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Fichtner, Alexander, and Franz Schaefer. Acute kidney injury in children. Edited by Norbert Lameire. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0239.

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In the past few decades, the overall incidence of acute kidney injury (AKI) in paediatric patients has increased and the aetiological spectrum has shifted from infection-related and intrinsic renal causes towards secondary forms of AKI related to exposure to nephrotoxic drugs and complex surgical, oncological, and intensive care manoeuvres. In addition, neonatal kidney impairment and haemolytic uraemic syndrome continue to be important specific paediatric causes of AKI raising unique challenges regarding prevention, diagnosis, and treatment. The search for new biomarkers is a current focus of
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Book chapters on the topic "Loop diuretics drugs"

1

Sun, Dandan. "The “Loop” Diuretic Drug Bumetanide-Sensitive Na + -K + -Cl - Cotransporter in Cerebral Ischemia." In New Strategies in Stroke Intervention. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-280-3_6.

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Goel, Harsh, and Ashish Kumar. "Diuretics in hypertension." In Hypertension (Oxford Cardiology Library) 3E, 3rd ed., edited by Sunil K. Nadar and Gregory Y. H. Lip. Oxford University PressOxford, 2022. http://dx.doi.org/10.1093/med/9780198870678.003.0014.

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Abstract Diuretics are effective as sole agents for early-stage hypertension or in combination with other antihypertensive drugs for more severe hypertension. Although grouped together in one class as diuretics, they vary greatly in terms of mode of action, efficacy, indications and tolerability. The choice of diuretic depends on various factors, including age, ethnicity, and comorbidities. Loop diuretics are more effective than thiazide diuretics in advanced renal failure. Aldosterone antagonists like spironolactone are preferred in patients with difficult to control or resistant hypertension
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Forde-McLean, Rhondalyn, and Mariell Jessup. "HFrEF pharmacological treatment: diuretics." In ESC CardioMed. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0423.

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Diuretics are an important part of the therapy for heart failure with reduced ejection fraction (HFrEF). These agents lead to amelioration of clinical symptoms and improvement in haemodynamics. There is little evidence, however, to support an association between diuretic use and improved clinical outcomes. The consensus guidelines for the use of diuretics are predominantly based on expert opinion. The principal diuretics used for HFrEF are the loop diuretics, thiazide and thiazide-like drugs, and potassium sparing agents. Their use is supplemented by the carbonic anhydrase inhibitors and vasop
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Rossignol, Patrick, and Kevin Damman. "Alterations in renal haemodynamics and function in heart failure." In The ESC Textbook of Heart Failure, edited by Petar M. Seferović, Andrew J. S. Coats, Gerasimos Filippatos, Stefan D. Anker, Johann Bauersachs, and Giuseppe Rosano. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/med/9780198891628.003.0026.

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Abstract Chronic kidney disease is a highly prevalent condition among patients with heart failure and is associated with worse clinical outcomes. Acute and chronic heart failure are inherently unstable conditions, encompassing a subtle (dis)equilibrium with kidney (dys)function within cardiorenal syndromes. Keeping in mind that lifesaving drugs (e.g. renin–angiotensin–aldosterone system inhibitors, including mineralocorticoid receptor antagonists, angiotensin receptor–neprilysin inhibitors, and/or sodium–glucose cotransporter 2 inhibitors) may alter kidney function without compromising clinica
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Li, Jie Jack. "Amlodipine (Novasc)." In Top Drugs. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780199362585.003.0007.

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Hypertension (high blood pressure) is estimated to afflict 1 billion individuals worldwide and is a major risk factor for stroke, coronary artery disease, heart failure, and end-stage renal disease. The first class of drugs to treat hypertension was the mercurial diuretics, discovered by Alfred Vogl in 1919 in Vienna. Diuretics, by removing fluid from the body, reduce the pressure on the heart. Mercurial diuretics revolutionized the treatment of congestive heart failure resulting from severe edema and were the primary treatment until the late 1950s, when thiazide diuretics emerged. In 1957, Me
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Duncan, Richards, and Jeffrey Aronson. "Diuretics: Loop diuretics: BNF 2.2.2 and 2.2.4." In Oxford Handbook of Practical Drug Therapy. Oxford University Press, 2005. http://dx.doi.org/10.1093/med/1.1.med-9780198530077-div1-70.

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Kacew, Sam. "Pharmacology and Toxicology of Loop Diuretics in Pediatrics." In Drug Toxicity and Metabolism in Pediatrics. CRC Press, 2018. http://dx.doi.org/10.1201/9781351071529-7.

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