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1
Harley, James. "Addendum." Tempo, no. 212 (April 2000): 54. http://dx.doi.org/10.1017/s0040298200007671.
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I am writing to provide further information in response to inquiries about my recent article on performance issues in Gorecki's music (Tempo 211). The symposium I referred to, at which the composer was present, was titled ‘The Gorecki Phenomenon’, and, in addition to my own, included presentations by Adrian Thomas, Luke Howard, David Kopplin, Mark Swed, and Maria Anna Harley, who organized and chaired the event (and translated the commentaries of Mr Gorecki, who had much to say). This session, along with entire ‘Gorecki Autumn’ at the University of Southern California, was organized to celebrate the endowement of the Directorship of the Polish Music Reference Center by Dr Stefan and Mrs Wanda Wilk, founders of this important resource on Polish music in North America (the website can be consulted at http://www.usc.edu/dept/polishmusic/). A book collecting the research presented at this symposium, along with the lectures and interviews given by the composer during his time in Los Angeles, is forthcoming, edited by Ms Harley.
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Lohani, Ishwar. "Trotting down the memory lane." Journal of Society of Surgeons of Nepal 20, no. 2 (2017): 1–3. http://dx.doi.org/10.3126/jssn.v20i2.24373.
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Born on 1962 at Kamaladi, Kathmandu, Prof Ishwar Lohani completed School Leaving Certificate from St. Xavier’s School. Lalitpur. followed by Senior Cambridge ‘O’ Level from Cambridge University 1980 and Proficiency Certificate Level from Amrit Science Campus. 1984.
 He did B. Muse. (Sangeet Prabhakar) in Tabala from Kalanidhi Sangit Manavidyalaya under Prayag Sangit Samiti, Allahabad. 1983.
 He completed M.B.B.S Degree from Madurai Medical College under Madurai Kamaraj University, Madurai, Tamilnadu, India. 1991 and MS General Surgery from PGIMER, Chandigarh, India. 1994.
 After completion of M.Ch. Plastic Surgery from PGIMER, Chandigarh, India in 1997, he worked initially as a Senior Medical Officer for few months and later as Senior Resident in the Dept. of Surgery, Chandigarh Medical College. He completed fellowship in Plastic Surgery as PSEF International fellow from University of Southern California, Los Angeles and California Pacific Medical Center, San Francisco May 2001 to Feb 2002 under Dr. Randy Sherman and Dr. Bryant Toth. He later did fellowship in Plastic Surgery through the Scottish Foundation for Surgery in Nepal at St. John’s Hospital, Livingstone and Canniesburn Hospital Glasgow, England from Jan 17, 2003 to Feb 28, 2003 under Dr. Auf Quaba and Dr. David Soutar.
 Presently working as Professor and Head of Department, Dept. of Plastic Surgery and Burns at the T.U. Teaching Hospital, Maharajgunj, Kathmandu, Nepal. He has been involved in the training of MBBS, MS (General Surgery) and MCh Plastic surgery graduates at the Maharajgung Medical Campus.
 He served as the President of the International College of Surgeons (ICS) Nepal Section; General Secretary of Association of Plastic Surgeons of Nepal (APSON). He has been member of Society of Surgeons of Nepal since 1996 and has contributed a lot in the activities of the society. He has presented in numerous National and International conferences and has numerous publications in international and national journals as well. He served as the Chief Editor of the Journal of Society of Surgeons of Nepal 2008 – 2014.
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Reddy, Sivapriya Thumati, Shili Ge, Dechu Puliyanda, et al. "Low T Cell Function in Preterm Neonates (PN) as Analyzed by Cylex ImmuKnow Assay (ICF) May be Responsible for a Higher Rate of Infection (134.47)." Journal of Immunology 182, no. 1_Supplement (2009): 134.47. http://dx.doi.org/10.4049/jimmunol.182.supp.134.47.
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Abstract Background: Cell mediated immunity is a critical defense mechanism against various pathogens. Lymphocyte number and function, and their links to risk for infection in neonates are not well understood. ICF measures immune function by assessing ATP levels in mitogen stimulated CD4+ cells. We investigate CD4+ cell function in neonates and the implication for infections. Methods: Heparinized cord blood from 30 term neonates (TN) and 3 PN (25-28 weeks) were submitted for ICF. Results: ATP levels were significantly lower in PN than TN (221 + 49 vs. 588 + 293 ng/ml, p<0.02). All 3 PN were exposed to maternal chorioamnionitis and treated postnatally for clinical sepsis, while none of the TN showed evidence of infection. In TN, the 18 vaginally delivered (VD) had significantly higher ATP levels than 12 born by cesarean (CS) (731±255 vs. 373±206 ng/ml, p<0.001). Of the 12 TN born by CS, 3 were exposed to labor and 9 were not, and showed similar ATP levels (277±110 vs. 405±225 ng/ml, NS). All 3 PN (1 CS) exposed to labor had low ATP levels. Conclusions: 1) CD4+ cell function is significantly lower in PN than TN, 2) VD in TN, but not CS w/ or w/o labor, increases ATP levels, suggesting that delivery via the birth canal is stressful for the TN and stimulates immune response, 3) ATP levels are not elevated in PN despite VD, suggesting that immune response in PN is poor, and may be partly responsible for a higher rate for infection in this patient population. Research Sponsors: Dept. of Pediatrics & Transplant/Immunology Lab, Cedars-Sinai Medical Center, Los Angeles, CA
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Martinez, Norberto. "Eusebio E. Llamas, MD (1926-2021) “Small in Feet but Giant in Feat”." Philippine Journal of Otolaryngology Head and Neck Surgery 36, no. 2 (2021): 62. http://dx.doi.org/10.32412/pjohns.v36i2.1831.
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Dr. Eusebio E. Llamas was the epitome of a great teacher, a devoted father and a prime mover. In 1952, he underwent residency training in Bellevue, New York where he stayed for one year and then proceeded to Los Angeles where he trained at the House Ear Institute. Upon his return to the Philippines, he joined the UST Department of EENT and subsequently became the section chief of ENT. In 1978, he assumed the chairmanship of the Department of EENT until 1983.
 
 As prime mover, he was instrumental in the separation of the Dept. of Otolaryngology from the Dept. of Ophthalmology in 1984 and led the department until 1989 earning the distinction of becoming the longest serving chair.
 
 He would invite residents (who were in awe of his demeanor in handling patients) to see interesting cases in his private clinic. He demonstrated compassion to all patients regardless of their social status. In the operating room, he exemplified finesse in doing surgeries and made it look so simply seamless. He never showed any mean streak and always appeared calm even amid adversity. Whenever there were issues in the department or among residents, he would talk to them in private and would counsel them like a father to his children.
 
 He was deeply religious as he would go to the chapel first thing in the morning before he went to the OPD at 8 am sharp. He taught the residents the virtue of punctuality by being at the OPD ahead of them, and 30 minutes in advance of his scheduled operations. He was impeccable in his choice of apparel, always dressing up with the perfect triangle of the Windsor tie
 
 The only reason why I wanted to become an ENT as early as third year medical student was solely because of Dr. Llamas. He would literally deliver his lecture verbatim from Boise’ Textbook of Otolaryngology including pauses for commas. He inspired me a lot and told myself, I wish I could do at least half of what he could memorize and that would be good enough
 
 He was very open to inviting graduates from other institutions to join the department as exemplified by the acceptance of Dr. Carlos Reyes for Otology and Dr. Robie Zantua for Head and Neck Surgery. He was never threatened by other consultants practicing at UST and in fact encouraged them to do so.
 
 He was a dedicated father to his children Rose, Jun, Beth and Annie and a devoted husband to his wife Lulu. He would always think of his family’s welfare over his own. His extended family would always seek his support whenever the need arose, and he would welcome them with open arms. To the family, thank you for generously sharing Dr. Llamas during his most productive years.
 
 The best tribute the PSO-HNS offered to Dr. Llamas was choosing him as the Most Outstanding Teacher in 2020. We would not be where we are today if not for the selfless dedication of our dear Dr. Llamas. As Thornton Wilde said, “The highest tribute to the departed is not grief but gratitude”.
 
 Maraming Salamat at Paalam
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Manning, R. Douglas. "Reboot: Major League Soccer’s 2018 Relaunch of Chivas USA as the Los Angeles Football Club." Case Studies in Sport Management 5, no. 1 (2016): 31–40. http://dx.doi.org/10.1123/cssm.2015-0042.
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The Los Angeles Football Club (LAFC) will begin play in 2018 as a new franchise in Major League Soccer (MLS). LAFC will replace Chivas USA as the second MLS franchise in the Los Angeles area. Chivas USA competed in 10 seasons of MLS, beginning with the 2005 season. Chivas USA was modeled after its parent organization, Club Deportivo Guadalajara (otherwise known as Guadalajara or Chivas Guadalajara) of the first-division Mexican League. MLS is highly regarded for its diversity initiatives, and Chivas USA was to focus on reaching the large Hispanic/Latino audience in the Los Angeles area. The club played alongside the Los Angeles Galaxy, one of MLS’s inaugural franchises, in the Home Depot Center (now StubHub Center) in Carson, California.
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Monastersky, R. "Los Angeles Faces a Dangerous Quake Debt." Science News 147, no. 3 (1995): 37. http://dx.doi.org/10.2307/3978971.
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Roy, Ananya, Hannah Appel, and Hilary Malson. "Towards justice: A communiqué from Los Angeles." Radical Housing Journal 2, no. 1 (2020): 163–72. http://dx.doi.org/10.54825/ghap7044.
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In this communiqué the Institute on Inequality and Democracy foregrounds the work of some of their movement partners — more appropriately understood as movement teachers — organizations that are on the frontline of the struggle against disposability and death in Los Angeles and beyond. They demonstrate the necessity of building a new common sense about relations of property and personhood, debt and wealth, reparation and redistribution.
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Deuchar, Ross, Simon Harding, Robert McLean, and James A. Densley. "Deficit or Credit? A Comparative, Qualitative Study of Gender Agency and Female Gang Membership in Los Angeles and Glasgow." Crime & Delinquency 66, no. 8 (2018): 1087–114. http://dx.doi.org/10.1177/0011128718794192.
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To date, there has been a paucity of comparative, qualitative research exploring the nuances of women’s gang involvement beyond the United States. In this article, we seek to address this gap by drawing upon qualitative interviews with small samples of self-nominated female gang members in Los Angeles, California (United States) and Glasgow, Scotland (United Kingdom). The emerging insights indicated that two key models of entry into the “social field” of the gang emerged in the data: a deficit model entry linked to drugs and debt and a credit model of entry where women were considered to bring social skill, expertise, and agency into the gang. Implications in terms of testable hypotheses for future research as well as for future practice are outlined.
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Bethel, A. C. W. "The Unfinished Web: Transit Planning in Los Angeles, 1895–1953." Southern California Quarterly 103, no. 1 (2021): 5–60. http://dx.doi.org/10.1525/scq.2021.103.1.5.
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Because of its complexity and length this article is organized into two parts. Part I, which appeared in the previous issue of the Quarterly, traced attempts to improve rapid rail transit in Los Angeles from 1895 to 1925. This concluding installment traces the political, civic, and taxpayer response to the 1925 comprehensive regional rapid transit plan. The plan was eclipsed by a seemingly unrelated controversy about a union station for the steam railroads. Meanwhile, though frustrated in its plan for a crosstown subway, the rapid transit provider, the Pacific Electric Railway (PE), was not passive: it worked cooperatively with other public-sector and private-sector agencies to create viaducts that separated its trains from busy intersections, bought new rolling stock, and installed safety measures. The emerging multi-destinational, automobile-oriented city of the 1930s and 1940s led planners to include rail rapid transit in freeway medians, but the politically powerful State Division of Highways opposed it, as did various civic and commercial organizations and the Automobile Club of Southern California (ACSC). Sectional differences in how residents perceived their interests divided city council and state legislature support. PE’s management, now discouraged, gradually abandoned and finally sold its passenger service. Part II concludes with an examination of the PE’s financial condition in the 1920s in refutation of the often-made claim that the PE’s high debt and unprofitable financial account sheets precluded it from making capital investments.
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Santi, Marina Rodrigues, Mayara dos Santos Noronha, Fernanda Rodrigues Borges Amaral Guarato, and Milena Maria Pierre dos Santos Caldeira. "Laminados cerâmicos e preparos minimamente invasivos associados ao clareamento dental." ARCHIVES OF HEALTH INVESTIGATION 9, no. 5 (2020): 429–32. http://dx.doi.org/10.21270/archi.v9i5.4771.
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A indicação de laminados cerâmicos deve ser precedida de um diagnóstico criterioso, onde deve-se estar atento aos passos e aspectos clínicos envolvidos nesse tipo de reabilitação. Este relato de caso tem como objetivo descrever a sequência clínica de uma reabilitação estética dos dentes 11 e 21 empregando laminados cerâmicos de dissilicato de lítio com desgaste dental seletivo minimamente invasivo associado ao clareamento prévio, proporcionando a reprodução das características naturais dos dentes.Descritores: Clareamento Dental; Cerâmica; Estética Dentária.ReferênciasD'Arcangelo C, De Angelis F, Vadini M, D'Amario M. Clinical evaluation on porcelain laminate veneers bonded with light-cured composite: results up to 7 years. Clin Oral Investig. 2012;16(4):1071-79.Benetti AR, Miranda CB, Amore R, Pagani C. Facetas indiretas em porcelana-alternativa estética. J Bras Dent Estét. 2003;2(7):186-94.Teixeira HM, Nascimento ABL, Emerrenciano M. Reabilitação da Estética com Facetas Indiretas de Porcelana. J Bras Dent Estét. 2003;2(7):219-23.Jarad FD, Griffiths CE, Jaffri M, Adeyemi AA, Youngson CC. The effect of bleaching, varying the shade or thickness of composite veneers on final colour: an in vitro study. J Dent. 2008;36(7):554-59.Lowe E. Achieving total smile enhancement through tooth whitening and placement of a single anterior veneer restoration. Dent Today. 2001;20(12):44-8Fradeani M, Redemagni M, Corrado M. Porcelain laminate veneers: 6- to 12-year clinical evaluation-a retrospective study. Int J Periodontics Restorative Dent. 2005;25(1):9-17. Aquino APT, Cardoso PC, Rodrigues MB, Takano AE, Porfírio W. Facetas de porcelana: solução estética e funcional. Clin int j braz dent. 2009;5(2):142-52.Higashi C, Reggiani RD, Kina S, Scopin O, Hirata R. Cerâmicas em Dentes Anteriores Parte I. Indicações Clínicas dos sistemas cerâmicos. Clin int j braz dent. 2006;2(1):22-31.Kina S, Brugrera A. Inivisível: restaurações estéticas cerâmicas. Maringá: Dental Press; 2007.
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Chai, Yufu, and William J. Hinze. "Gravity inversion of an interface above which the density contrast varies exponentially with depth." GEOPHYSICS 53, no. 6 (1988): 837–45. http://dx.doi.org/10.1190/1.1442518.
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Mapping of an interface above which the density contrast varies exponentially with depth, as is common at the basement surface of sedimentary basins, is efficiently achieved by a theoretically precise gravity method which can be applied to either profile data or twodimensional data. The contrast in mass above the interface is modeled by an array of vertical rectangular prisms with density contrasts varying exponentially with depth. Gravity anomalies due to the prisms are calculated in the wavenumber domain and then converted to the space domain. The precision of the inverse numerical Fourier transform in this procedure is significantly increased by a shift‐sampling technique based on the discrete Fourier deviation equation. Depth to the interface is determined by iterative adjustment of the vertical extent of the prisms in accordance with observed gravity anomaly data. The basement surface of the Los Angeles basin, California, calculated by this method, closely duplicates the published configuration based on drillhole data and seismic data.
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Medeiros, Brian, Alex Hall, and Bjorn Stevens. "What Controls the Mean Depth of the PBL?" Journal of Climate 18, no. 16 (2005): 3157–72. http://dx.doi.org/10.1175/jcli3417.1.
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Abstract The depth of the planetary boundary layer (PBL) is a climatologically important quantity that has received little attention on regional to global scales. Here a 10-yr climatology of PBL depth from the University of California, Los Angeles (UCLA) atmospheric GCM is analyzed using the PBL mass budget. Based on the dominant physical processes, several PBL regimes are identified. These regimes tend to exhibit large-scale geographic organization. Locally generated buoyancy fluxes and static stability control PBL depth nearly everywhere, though convective mass flux has a large influence at tropical marine locations. Virtually all geographical variability in PBL depth can be linearly related to these quantities. While dry convective boundary layers dominate over land, stratocumulus-topped boundary layers are most common over ocean. This division of regimes leads to a dramatic land–sea contrast in PBL depth. Diurnal effects keep mean PBL depth over land shallow despite large daytime surface fluxes. The contrast arises because the large daily exchange of heat and mass between the PBL and free atmosphere over land is not present over the ocean, where mixing is accomplished by turbulent entrainment. Consistent treatment of remnant air from the deep, daytime PBL is necessary for proper representation of this diurnal behavior over land. Many locations exhibit seasonal shifts in PBL regime related to changes in PBL clouds. These shifts are controlled by seasonal variations in buoyancy flux and static stability.
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Sonsteng-Person, Melanie, Lucero Herrera, Tia koonse, and Noah D. Zatz. "“Any Alternative Is Great If I’m Incarcerated”: A Case Study of Court-Ordered Community Service in Los Angeles County." Criminal Justice and Behavior 48, no. 1 (2020): 32–53. http://dx.doi.org/10.1177/0093854820923373.
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California courts increasingly order community service for those convicted of nonviolent and minor misdemeanors or infractions, assigning unpaid work to be performed. While court-ordered community service has been used as an alternative to incarceration and the payment of fines, little is known about the monetary and personal costs for those completing it. A case study design is used to examine court-ordered community service performed in Southeast Los Angeles. Data were gathered from a quantitative dataset of 541 court files of those assigned to community service and 32 in-depth interviews with attorneys and court-ordered community service workers. While the quantitative data and Attorney interviews found that negative outcomes of community service can drive community service workers deeper into debt and result in new warrants that place defendants at risk for rearrest, individuals that completed community service appreciated the opportunity to pay off their criminal justice debts and stay out of jail.
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Jagsi, Reshma, John A. E. Pottow, Kent A. Griffith, et al. "Long-Term Financial Burden of Breast Cancer: Experiences of a Diverse Cohort of Survivors Identified Through Population-Based Registries." Journal of Clinical Oncology 32, no. 12 (2014): 1269–76. http://dx.doi.org/10.1200/jco.2013.53.0956.
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Purpose To evaluate the financial experiences of a racially and ethnically diverse cohort of long-term breast cancer survivors (17% African American, 40% Latina) identified through population-based registries. Methods Longitudinal study of women diagnosed with nonmetastatic breast cancer in 2005 to 2007 and reported to the SEER registries of metropolitan Los Angeles and Detroit. We surveyed 3,133 women approximately 9 months after diagnosis and 4 years later. Multivariable models evaluated correlates of self-reported decline in financial status attributed to breast cancer and of experiencing at least one type of privation (economically motivated treatment nonadherence and broader hardships related to medical expenses). Results Among 1,502 patients responding to both surveys, median out-of-pocket expenses were ≤ $2,000; 17% of respondents reported spending > $5,000; 12% reported having medical debt 4 years postdiagnosis. Debt varied significantly by race: 9% of whites, 15% of blacks, 17% of English-speaking Latinas, and 10% of Spanish-speaking Latinas reported debt (P = .03). Overall, 25% of women experienced financial decline at least partly attributed to breast cancer; Spanish-speaking Latinas had significantly increased odds of this decline relative to whites (odds ratio [OR], 2.76; P = .006). At least one privation was experienced by 18% of the sample; blacks (OR, 2.6; P < .001) and English-speaking Latinas (OR, 2.2; P = .02) were significantly more likely to have experienced privation than whites. Conclusion Racial and ethnic minority patients appear most vulnerable to privations and financial decline attributable to breast cancer, even after adjustment for income, education, and employment. These findings should motivate efforts to control costs and ensure communication between patients and providers regarding financial distress, particularly for vulnerable subgroups.
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Paulukonis, Susan, Lynne Neumayr, Thomas D. Coates, Elliott Vichinsky, and Lisa Feuchtbaum. "Emergency Room Utilization by California Sickle Cell Patients During Pediatric to Adult Care Transition." Blood 116, no. 21 (2010): 254. http://dx.doi.org/10.1182/blood.v116.21.254.254.
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Abstract Abstract 254 Clinical experience and research with sickle cell patients and those with other genetic diseases suggests that the period of “transition,” in which patients move from pediatric care to adult-centered clinical care, is a period of high health services utilization. Young adult patients may not have learned to effectively manage disease symptoms and may not be connected to a “medical home” or have established a relationship with a primary care physician or adult hematologist. Further, these patients may not have insurance coverage previously provided by parents or by public pediatric insurance programs. As part of a collaborative agreement through the Centers for Disease Control and Prevention (CDC) and the National Heart, Lung & Blood Institute (NHLBI), California and five other states are conducting epidemiologic surveillance to determine the prevalence of hemoglobinopathies as well as health services utilization. Such data are essential to inform allocation of resources to meet the medical and social service needs of patients. Within the state, this project is a collaborative effort among the CA Dept. of Public Health Genetic Disease Screening Program, Children's Hospital Los Angeles and Children's Hospital & Research Center Oakland. Using administrative data obtained as a part of this effort, we describe emergency room (ER) utilization patterns among young adults with sickle cell disease. The CA Office of Statewide Health Planning and Development has collected data on ER utilization for the years 2005 – 2008. Using ICD 9 codes beginning with 282.6 to identify sickle cell-related ER visits during those years, we report usage patterns by patient age, gender, and payer type. To calculate risk of repeat ER visits, we used a negative binomial regression model (with 1 visit as the baseline for analysis, rather than 0 visits, due to the limitations of the data set). The following means and counts are adjusted to account for this shift. Analyses were conducted using SAS 9.1. The mean number of ER visits among sickle cell patients in the data set was 3.36 per year and 54% of visits were made by women, but gender differences in average visits per year per patient (3.18 female, 3.60 male) were not statistically significant. Medi-Cal (Medicaid) was the primary payer for 47% of visits during this time frame, and patients with Medi-Cal averaged nearly one additional visit per year (3.82 visits) compared to patients with other forms of payment (3.04 visits). Among patients seen at any time during the four years and controlling for gender and payer type, we found a 78% increase (IRR 1.78, 95% CI 1.59, 2.00) in risk of visiting the ER a second or subsequent time in a given year among the 20 to 30 year old group compared to all other age groups, a four fold increase (IRR 4.22, 95% CI 3.61, 4.93) in risk of a second or subsequent visit in a year compared to the group aged 10 to 20 years, and a 30% increase (IRR 1.34, 95% CI 1.16, 1.55) compared to the group 30 to 40 years of age. Average number of visits in the transition age group was 4.53 per year, compared to 1.93 per year in the 10 to 20y group and 3.56 in the 30 to 40y age group. The number of individuals visiting the ER per year was higher in this age group compared to the two adjoining age groups (520 individuals on average per year for 20 – 30y, vs. 311 per year for 10 – 20y and 355 for 30 to 40y). The increase in visits per year of age can be seen (Figure 1) to begin at age 18 or 19 and continue to approximately age 30. The proportion of patients with no insurance coverage increased from 8% in the 10 to 20y age category to 19% of patients in the 20 to 30y age category, and remains high for the subsequent age categories (11 to 17%). The transition period from pediatric care to adult care in California sickle cell patients is marked by a dramatic increase in emergency room visits (both more patients visiting and more visits per patient) compared to other age groups. ERs are also visited significantly more often by uninsured sickle cell patients in this age group than other age groups. Patients in this age group would likely benefit from access to a medical home model of care.Figure 1.Mean Annual Number of Visits by Age of Patient among Those Seen in ER with SCD-related ICD 9 Codes, California, 2005–2008Figure 1. Mean Annual Number of Visits by Age of Patient among Those Seen in ER with SCD-related ICD 9 Codes, California, 2005–2008 Disclosures: Coates: Novartis: Research Funding, Speakers Bureau.
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Markusen, A. "The Military-Industrial Divide." Environment and Planning D: Society and Space 9, no. 4 (1991): 391–416. http://dx.doi.org/10.1068/d090391.
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In the debate on the incidence and dynamics of new industrial complexes, technological innovation has been treated as exogenous, and endogenous entrepreneurial growth forces have been stressed at the expense of state actions, interregional interactions, and geographical transfers of capital and labor. In this paper it is argued that technological paths are deliberately chosen and that the state, through its commitment to cold-war armament, has been a major source of demand for and underwriter of the new flexible technologies and new product lines so central to the new industrial districts phenomenon in the USA. The emergence of specific agglomerations, such as Los Angeles, Orange County, Silicon Valley, and the Boston area's Route 128, and the parallel failure of the industrial heartland cities to host military-related high-tech development, are the products of concerted locational choice and developmental efforts by military personnel, politicians, boosters, and military-industrial corporate managers, Military-led innovation has furthermore contributed to the rise of accelerated and institutionalized innovation and to the emergence of new macroeconomic pathologies, such as state debt, accelerated deindustrialization, and a worsening income distribution.
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Bornstein, Marta, Jessica D. Gipson, Roselle Bleck, Aparna Sridhar, and Agatha Berger. "Perceptions of Pregnancy and Contraceptive Use: An In-Depth Study of Women in Los Angeles Methadone Clinics." Women's Health Issues 29, no. 2 (2019): 176–81. http://dx.doi.org/10.1016/j.whi.2018.10.004.
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Khan, Tabinda Nawaz, and Farhan Raza Khan. "Determination of Lead, Arsenic and Chromium Contents in Two Types of Mineral Trioxide Aggregate Using Atomic Absorption Spectrometry." Journal of the Pakistan Dental Association 29, no. 04 (2020): 223–27. http://dx.doi.org/10.25301/jpda.294.223.
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OBJECTIVE: To evaluate the acid-soluble Arsenic, Lead, and Chromium contents in the two varieties of Mineral Trioxide Aggregate (MTA) using Atomic Absorption Spectrophotometry. METHODOLOGY: Analysis of Arsenic, Lead, and Chromium in the two products of MTS [MProRoot MTA and MTA Angelus] were done using graphite furnace atomic absorption spectrophotometry employing 2.4 mol/L of hydrochloric acid for digestion of materials. The test materials were subjected to incubate in water and simulated body fluid (SBF) so that the leach out metal ions from the material can also be quantified. Descriptive statistics reported along with ANOVA for comparison of quantitative analysis of Arsenic, Lead, and Chromium in the extracts of the two MTA products. One way ANOVA was applied to compare the leach out of metals over 15 days. Level of significance was kept at 0.05. RESULTS: Both varieties of MTA [ProRoot MTA and MTA Angelus] leached out extracts into water and SBF showing lower values of Arsenic and Lead contents in accordance to the limit set by ISO 9917-1 (2007). However, extracts of both the products had comparatively higher amount of Chromium ions. CONCLUSIONS: The total amount of Arsenic, Chromium, and Lead released from the two cements were found to be far below than what is considered as clinically harmful. KEYWORDS: Chromium; Arsenic; Lead, heavy metals; Mineral trioxide aggregate HOW TO CITE: Khan TN, Khan FR. Determination of lead, arsenic and chromium contents in two types of mineral trioxide aggregate using atomic absorption spectrometry. J Pak Dent Assoc 2020;29(4):223-227.
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Nijland, J., T. L. M. Verdoes, M. P. Lycklama Nijeholt, and N. T. Pham. "Hostile Takeovers: Desirable or Dangerous? A Survey Study into the Circumstances Under Which Hostile Takeovers in the Netherlands Are (Un)Permissible." European Journal of Interdisciplinary Studies 7, no. 1 (2021): 77. http://dx.doi.org/10.26417/291vza59o.
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A number of recent hostile takeover attempts in The Netherlands have triggered the discussion in the Netherlands on the circumstances under which protection of the target company against a hostile takeover should be justified or not be justified. To answer this question, 21 experts involved in mergers and acquisitions from various angels on the highest (management) level, were selected to participate in a survey investigation combining open questions and giving scores for submitted factors. The outcomes show that the participants advocate non-protection in case of relatively high performance of the bidding company, new value creating opportunities a non-responsive board of the Target with personal interest of the board, and cash payment for the target. They are in favor of protection in case of takeover attempts that incur personal board benefits of bidder or target, intended debt push down financing, and in case of considerable societal risks and consequences.
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Batrancea, Larissa M., Mehmet Ali Balcı, Leontina Chermezan, Ömer Akgüller, Ema Speranta Masca, and Lucian Gaban. "Sources of SMEs Financing and Their Impact on Economic Growth across the European Union: Insights from a Panel Data Study Spanning Sixteen Years." Sustainability 14, no. 22 (2022): 15318. http://dx.doi.org/10.3390/su142215318.
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Getting access to sufficient funding is the keystone for the development of any business, but especially for small and medium enterprises (SMEs). These economic entities are crucial players in the global economy since they include almost 90% of companies, provide jobs for nearly 50% of the global workforce, and enhance long-term economic growth. In this context, our study explores important sources concerning the financing of small and medium enterprises and their impact on economic growth during the period 2005–2020 with data from SMEs covering the 28 countries belonging to the European Union. The set of predictors included Strength of legal rights index, Days sales outstanding, Bad debt loss, Interest rate, Bank support, Business angels, Private lenders, and Public support. The set of dependent variables included Cost of loans, Equity fund, GDP growth rate, and Value added growth rate. Our methodological approach was complex, it considered a panel data analysis with a first-difference generalized method of moments estimator and a multiplex time series analysis. The novelty of the study resides in combining the two methods in order to investigate significant drivers of economic growth across the EU. Empirical results showed that economic growth was mainly triggered by predictors such as Interest rate, Business angels, Bank support, and Public support. Moreover, the valuable mathematical insights elicited by the multiplex time series analysis suggested that European economies cooperated intensively through SME activities. Based on our empirical results, national and regional authorities should enact adequate policies to support business endeavors of small and medium enterprises.
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Gnatchenko, Y., S. Yurieva, and N. Volgina. "INNOVATIVE ENTERPRENEURSHIP DEVELOPMENT MANAGEMENT ON MACRO LEVEL." Series: Economic science 2, no. 162 (2021): 92–98. http://dx.doi.org/10.33042/2522-1809-2021-2-162-92-98.
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Government policy issues and approaches of improvement innovative entrepreneurship are considered in the paper. Elements of policy intervention on innovative entrepreneurship were described. The way firm innovate and the nature of their contributions to innovation varies and depends critically on firm characteristics and the conditions they face to engage in innovation. The “technology push” and “market pull” models provide two perspectives on firm innovation. Innovation output may differ along the several dimensions, including the type of innovation and the impact of innovation. Innovation can play a critical role in addressing socio-economic objectives, which are affected by the following factors: economic growth and employment, environmental challenges, social challenges. Innovative entrepreneurship can contribute to socio-economic challenges by formalizing the informal sector. The main policy approaches to address challenges associated to policy intervention for innovative entrepreneurship deal with: institutional governance, strategy and coherence of policies, policy-making contexts for innovative entrepreneurship. Achieving coherence and balance in the set of policies affecting innovative entrepreneurship, and coordinating the various actors involved in these policies have, consequently, become increasingly important for policy efficiency. Specific rationales for public policies: access to finance, access to knowledge, access to labor, entrepreneurial capabilities and culture, market development and access, regulatory framework. Access to finance is a key driver in the creation, survival and growth of innovative new ventures. Within the context of innovative entrepreneurship, public policy can in the following ways: debt financing, venture capital, business angels, private sources of funding. Access to debt financing is a critical issue for innovative businesses. It allows them to finance their growth, meet working capital requirements and invest in innovation. Relevant to innovative entrepreneurs are alternative types of loans, such as convertible and subordinated loans. Convertible loans give lenders the right to convert credit into an equity participation in the company, whereas subordinated loans are junior forms of debt that, in case of insolvency, have lower priority than senior debt (e.g. asset-based lending). They are riskier but pay higher interest rates.
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Jiang, Li, Jianzhong Zhang, and Zhibing Feng. "A versatile solution for the gravity anomaly of 3D prism-meshed bodies with depth-dependent density contrast." GEOPHYSICS 82, no. 4 (2017): G77—G86. http://dx.doi.org/10.1190/geo2016-0394.1.
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We have developed a generalized solution for computing the gravity anomalies of 3D irregular-mass bodies with complicated density-contrast variation. The 3D irregular-shaped bodies can be approximated flexibly by a collection of finite-juxtaposed right-rectangular prisms. The complicated density-contrast variation of each prism can be well-represented by a depth-dependent polynomial function. A novel analytic solution of gravity anomalies due to a right-rectangular prism with an arbitrary order of polynomial density-contrast function of depth is then derived. The solution is singularity free in the upper half-space over the prism, and its singularity in the lower half-space containing the prism is resolved by assigning their limit values to the singular terms. The numerical stability of the solution is also evaluated through numerical tests. Hence, the solution can be used to compute the gravity anomalies of 3D irregular bodies with variable density contrasts without singularities when computation points are within the numerical stability range. Based on synthetic models with variable density contrast, our solution is validated by using other solutions in the literature. We also simulated the gravity anomalies of the Los Angeles basin and compared them with the observed anomalies and with those computed using the analytic solutions of other workers. These tests confirm the accuracy and efficiency of our analytic solution.
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Statham, A. K., and M. A. Georgeson. "Stereo Depth Perception Uses First-Order Phase and Second-Order Position Disparities." Perception 26, no. 1_suppl (1997): 370. http://dx.doi.org/10.1068/v970162.
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We examined the nature and variety of cues underlying the use of binocular disparity in depth perception. Stimuli were Gabor patches (Gaussian-windowed sine-wave gratings, 2 cycles deg−1) and horizontal disparities were produced by varying the phase of the carrier grating or the position of the Gaussian envelope (SD=24 min arc), or both. Disparity varied from −180° to +180° of carrier phase (or the positional equivalent) at carrier orientations 0°, 30°, 60° or 90° from vertical. Direction and magnitude of perceived depth were reported in a 2IFC procedure where the comparison interval contained a zero disparity vertical patch. Use of different orientations allowed phase disparity to be distinguished from horizontal position disparity. Two main conditions were tested. (1) In the ‘patch’ condition carrier and envelope disparity varied together, and perceived depth was found to vary monotonically with positional disparity. When carrier disparity was ambivalent (at ±180° phase disparity) or zero (with horizontal orientation) perceived depth followed envelope disparity, showing that 2nd-order (envelope) disparity alone can produce depth. (2) When carrier disparity was varied with the envelope held fixed, perceived depth and discrimination thresholds depended on phase disparity rather than horizontal position disparity, lending support to the phase-based theory of De Angelis, Ohzawa, and Freeman (1995 Perception24 3 – 31). At the larger crossed disparities (−90° to −180°) depth reversed sign, suggesting a role for occlusion cues as well as phase and envelope disparity in stereo depth coding.
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Jagsi, Reshma, John A. E. Pottow, Kent A. Griffith, et al. "Racial and ethnic variation in employment and financial experiences of breast cancer survivors." Journal of Clinical Oncology 31, no. 15_suppl (2013): 9601. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.9601.
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9601 Background: Concerns exist regarding the employment and financial experiences of cancer survivors and whether they differ by race/ethnicity. Methods: In a longitudinal survey of women reported to the Los Angeles and Detroit SEER registries for nonmetastatic breast cancer, we compared experiences of 4-year survivors by race/ethnicity. Results: Overall, 31% of 1,536 respondents (68% response rate) felt their financial status was worse since diagnosis (63% attributed this to breast cancer). This varied by race/ethnicity: 41% of Spanish-speaking Latinas (SSL), 33% English-speaking Latinas (ESL), 23% blacks (B), and 29% whites (W), p<0.001. The median respondent had spent ≤$2000 on breast cancer medical expenses; 16% had spent >$5000. 12% had medical debt 4 yrs post-diagnosis: 17% of ESL, 14% B, 10% SSL, and 9% W (p=0.01). Minority respondents were more likely to report foregoing medical care due to cost and other privations due to their medical expenses (Table). Overall, 14% felt their employment status was worse since diagnosis, and 61% of these attributed this to breast cancer. 755 worked for pay some time after diagnosis, of whom 56% said it was at least somewhat important to work to keep health insurance (55% of SSL, 65% ESL, 65% B, 50% W, p=0.03); 24% would look for a new job if assured of comparable benefits (45% of SSL, 29% ESL, 22% B, 17% W, p<0.001); 7% had increased work hours to cover cancer-related expenses; 27% had decreased work hours due to cancer-related health issues; and 7% believed they had been denied job opportunities because of cancer. Conclusions: In this population-based sample of breast cancer survivors, job lock was common, and many women perceived being worse off with respect to finances and employment as a result of their breast cancer. Medical debt and privation varied significantly by race/ethnicity. [Table: see text]
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Gay, M., M. De Angelis, and J. L. Lacoume. "Dating a tropical ice core by time–frequency analysis of ion concentration depth profiles." Climate of the Past 10, no. 5 (2014): 1659–72. http://dx.doi.org/10.5194/cp-10-1659-2014.
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Abstract. Ice core dating is a key parameter for the interpretation of the ice archives. However, the relationship between ice depth and ice age generally cannot be easily established and requires the combination of numerous investigations and/or modelling efforts. This paper presents a new approach to ice core dating based on time–frequency analysis of chemical profiles at a site where seasonal patterns may be significantly distorted by sporadic events of regional importance, specifically at the summit area of Nevado Illimani (6350 m a.s.l.), located in the eastern Bolivian Andes (16°37' S, 67°46' W). We used ion concentration depth profiles collected along a 100 m deep ice core. The results of Fourier time–frequency and wavelet transforms were first compared. Both methods were applied to a nitrate concentration depth profile. The resulting chronologies were checked by comparison with the multi-proxy year-by-year dating published by de Angelis et al. (2003) and with volcanic tie points. With this first experiment, we demonstrated the efficiency of Fourier time–frequency analysis when tracking the nitrate natural variability. In addition, we were able to show spectrum aliasing due to under-sampling below 70 m. In this article, we propose a method of de-aliasing which significantly improves the core dating in comparison with annual layer manual counting. Fourier time–frequency analysis was applied to concentration depth profiles of seven other ions, providing information on the suitability of each of them for the dating of tropical Andean ice cores.
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Koçak, Mustafa Murat, Sibel Koçak, Elif Aybala Oktay, Abdullah Kiliç, and Sis Darendeliler Yaman. "In vitro Evaluation of the Minimum Bactericidal Concentrations of Different Root-End Filling Materials." Journal of Contemporary Dental Practice 14, no. 3 (2013): 371–74. http://dx.doi.org/10.5005/jp-journals-10024-1330.
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ABSTRACT Aim The aim of this study was to evaluate the minimum bactericidal concentrations (MBC) of root-end filling materials ProRoot MTA, MTA Angelus and IRM. Materials and methods Macrodilution broth method was used. Microorganisms used were: Staphylococcus aureus (ATCC 29213), Enterococcus faecalis (ATCC 29212) and Streptococcus mutans. Serial two-fold dilutions of root-end filling samples were prepared in macrodilution tubes with concentrations ranging from 1/2 to 1/512. The samples dilutions were incubated for 24 hours. After incubation, 0.1 ml of diluted culture was inoculated onto the surface of supplemented sheep blood agar (Merck, Germany) and all plates were incubated at 37°C in aerobic condition for 24 hours. The MBC was defined as the lowest concentration of root-end filling samples where no growth was recorded. Results MBC of both mineral trioxide aggregate (MTA) products against S. aureus were recorded as 15.62 mg/ml and for IRM 31.25 mg/ml MBC for both MTA groups against E. faecalis were recorded as 31.25 mg/ml and for IRM 62.5 mg/ml. MBC of all root-end filling samples against S. mutans were recorded as 62.5 mg/ml. Conclusion All tested root-end filling materials showed acceptable MBC against S. aureus and E. faecalis. Clinical significance All tested materials can be used safely for filling of a root-end cavity. How to cite this article Koçak MM, Koçak S, Oktay EA, Kiliç A, Yaman SD. In vitro Evaluation of the Minimum Bactericidal Concentrations of Different Root-End Filling Materials. J Contemp Dent Pract 2013;14(3):371-374.
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de Oliveira, Marilia Gerhardt, João Batista Blessmann Weber, Aline Tempel Costa, Francine Konrath, and Berenice Dedavid. "Marginal Adaptation of Root-end Filling Materials: An In vitro Study with Teeth and Replicas." Journal of Contemporary Dental Practice 10, no. 2 (2009): 75–82. http://dx.doi.org/10.5005/jcdp-10-2-75.
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Abstract Aim The purpose of this investigation was to evaluate the marginal adaptation of five root-end filling materials. Methods and Materials Fifty human single-rooted teeth were resected 3 mm from the apex. Root-end cavities were then prepared using an ultrasonic tip and filled with one of the following materials: silver amalgam without zinc, white MTA-Angelus, white Portland cement (PC), Vitremer™, and GC Fuji Ortho™ LC. The apical portion of the roots was then sectioned to obtain two 1 mm thick transversal sections. Epoxy resin replicas of these apical sections were fabricated for an analysis of marginal adaptation. Scanning electron microscopy (SEM) was used to determine gaps in the adaptation of the root-end filling materials at the interface between them and the dentin. The Kruskal-Wallis test and a multiple comparison test were used for statistical data analysis. The Spearman correlation coefficient was used to determine the correlation between the results found for teeth and replicas. Results Materials containing calcium oxide (MTA and PC) showed similar results. Resin modified glass ionomer cements (GICs) presented similar variations in marginal adaptation, but Vitremer™ showed significantly greater marginal adaptation when compared to GC Fuji Ortho™ LC. Conclusion A positive and significant correlation was observed between marginal adaptation values found in the teeth and their replicas. Clinical Significance The use of ionomers as root-end filling materials may improve clinical outcomes in periradicular surgery. Citation Costa AT, Konrath F, Dedavid B, Weber JBB, Oliveira MG. Marginal Adaptation of Root-end Filling Materials: An In vitro Study with Teeth and Replicas. J Contemp Dent Pract 2009 March; (10)2:075-082.
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Gupta, Pooja, Sathish Abraham, Aradhana B. Kamble, Archana Satpute, Salil Chaudhari, and Pushpak Ladhe. "In vitro Evaluation of the Efficacy of 2% Carbonic Acid and 2% Acetic Acid on Retrieval of Mineral Trioxide Aggregate and their Effect on Microhardness of Dentin." Journal of Contemporary Dental Practice 17, no. 7 (2016): 568–73. http://dx.doi.org/10.5005/jp-journals-10024-1891.
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ABSTRACT Introduction In this in vitro study, the efficacy of 2% carbonic acid and 2% acetic acid on the surface, microhardness of white mineral trioxide aggregate (MTA) and dentin after 1 day of setting and 21 days of setting of MTA is measured. Materials and methods Tooth molds were made using 60 single-rooted premolars by slicing them to 4 mm in the mid-root region. White MTA (Angelus) was mixed and packed in the molds. Three experimental groups were formed and exposed to 2% carbonic acid, 2% acetic acid, and saline for 10 minutes on 1 and 21 days of setting respectively. Vickers hardness test of white MTA and dentin was done before and after exposure. Data were subjected to analysis of variance (ANOVA) and post hoc tests. Results The results show that 2% acetic acid was significantly effective in reducing the microhardness of white MTA compared to 2% carbonic acid and saline on exposure for 10 minutes. Conclusion The results of the present study indicate that 2% acetic acid has maximum efficacy in reducing the surface microhardness of partial and completely set MTA, followed by 2% carbonic acid. Clinical significance The following study will help find an adjunct for retrieval of MTA, which was found difficult with the existing methods. How to cite this article Abraham S, Kamble AB, Gupta P, Satpute A, Chaudhari S, Ladhe P. In vitro Evaluation of the Efficacy of 2% Carbonic Acid and 2% Acetic Acid on Retrieval of Mineral Trioxide Aggregate and their Effect on Microhardness of Dentin. J Contemp Dent Pract 2016;17(7):568-573.
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Rathod, Nirav, Prachi Sood, and Nirmala Pasam. "Analysis and Comparison of Correlation between Camper's Plane and Natural Occlusal Plane in Normal Dentulous Subjects." International Journal of Prosthodontics and Restorative Dentistry 7, no. 3 (2017): 81–85. http://dx.doi.org/10.5005/jp-journals-10019-1182.
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ABSTRACT Background Orientation of the occlusal plane is one of the most important clinical procedures in the prosthodontic rehabili- tation of edentulous patients but definitions of the ala-tragus line (ATL) causes confusion, because the exact points of reference for this line are not clear. Aim The aim of this study was to corroborate a correlation between Camper's plane and natural occlusal plane in normal dentulous subjects and to ascertain the most relevant posterior reference point for establishing Camper's plane. Materials and methods In this study, 40 subjects with com- plete natural dentition and Angel's Class I occlusal relationship were selected. The subjects were photographed in sitting erect posture with head unsupported while clenching on a fox plane. The angles between the following lines were measured using digital screen protractor, the occlusal plane and Ala to superior border of tragus, the occlusal plane and Ala to middle border of tragus, as well as occlusal plane and Ala to inferior border of tragus. Descriptive statistics, one sample t-test and, independent t-test were done to analyze the data. Results There was no parallelism between the occlusal plane and ATL with three different posterior ends and one sample t-test showed that the angles between them were significantly different from zero (p < 0.001). However, the inferior border of the ATL had the lowest mean angle, 1.99° (4.32) and was almost parallel to the occlusal plane. Conclusion Ala-tragus line from Ala of the nose to the inferior border of tragus as a posterior reference point can be considered as a reliable occlusal plane for complete denture fabrication. How to cite this article Rathod N, Sood P, Pasam N. Analysis and Comparison of Correlation between Camper's Plane and Natural Occlusal Plane in Normal Dentulous Subjects. Int J Prosthodont Restor Dent 2017;7(3):81-85.
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Kuharski, Allen J. "Raised and Written in Contradictions: the Final Interview Jan Kott in conversation with Allen J. Kuharski." New Theatre Quarterly 18, no. 2 (2002): 103–20. http://dx.doi.org/10.1017/s0266464x02000192.
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Jan Kott invited me to conduct this formal ‘final interview’ early in 2001, after I shared with him a draft of the essay ‘Arden and Absolute Milan’ that follows. The essay and the interview were the culmination of over fifteen years of friendship and intermittent writing about Kott, which had extended to the translation of his works. I first met Jan and his wife Lidia at Berkeley in 1986, when they travelled from Los Angeles to see a production of Tadeusz Różewicz's White Marriage that I had directed and designed there, which proved the start of a long personal and professional relationship. I interviewed Kott at his modest apartment in Santa Monica, California, over the weekend of 31 March to 2 April 2001. Lidia had passed away the summer before, and his own health was extremely frail, requiring twenty-four-hour care by a group of charming and attentive Polish-speaking women. He shared his apartment after Lidia's death with an energetic black-and-white kitten, whose energy and mischief amused him greatly. Born in the Chinese Year of the Tiger, he had a cereal box decal of Tony the Tiger stuck next to the name-plate on his apartment door (the name Kott also means ‘cat’ in Polish). He was not able to move about without a nurse and a walking frame, but he nevertheless insisted on inviting me out to dinner in a local Polish restaurant, where he heartily ate a meal of steak tartar and flaczki (Polish tripe soup), accompanied by a shot or two of vodka. His nurse, who was with us, seemed amused but not at all astonished by this performance. Afterwards, he admitted this was his first meal out of the house in months – it was possibly his last. In spite of his physical weakness, Kott's mind remained lucid, and he had clearly rehearsed the interview extensively before our meetings in person. Most of the questions I had prepared proved unnecessary. What is published here is culled from approximately five hours of taped material, which Kott later edited along with myself. I owe a great debt of gratitude to my Philadelphia colleague, Helena Morawska White, for her time and energy in transcribing the taped interviews in Polish, and to Michal Zadara for his careful work in translating the unedited text into English.
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DIACHENKO, Danil, and Vlasta SHVAHIREVA. "The role of crowd funding in innovative activities." Economics. Finances. Law, no. 5/3 (May 26, 2021): 30–32. http://dx.doi.org/10.37634/efp.2021.5(3).8.
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The paper considers the concept of innovation and its importance and impact on modern social life. Budget and extra-budgetary forms of its financing are given: state financing, joint-stock, bank credits, venture financing, leasing, business angels, mixed form of financing and crowdfunding. In particular, the form of crowdfunding financing is considered. The purpose of this paper is to study and analyze the forms of crowdfunding financing, as well as to identify its role in the development of innovation. For this purpose, such research methods as analysis, study and evaluation of information were used. The concept of crowdfunding and the mechanism of financing projects through crowdfunding are considered. The sites of Internet sites that perform the function of fundraising by crowdfunding are considered – the site acts as a third party, is not responsible to anyone, only helping to cover the project and managing the funds raised. Any of the site visitors, who are usually not professional financiers, can transfer any amount to the account of the author of the project. The volumes and growth rates of crowdfunding in the world for 2014 are presented. The analysis and comparison of domestic and foreign crowdfunding platforms is carried out. The classification of crowdfunding by the method of reward (namely: “reward crowdfunding”, “equity crowdfunding” and “debt crowdfunding”), and by the method of fundraising (“all or nothing”, “leave everything”, “turning point”, “free” price”, "perpetual financing" and "subscription"). The paper also analyzes the advantages and disadvantages of this method of raising funds, its impact on the development of innovation. The conclusion states that despite all the disadvantages, no other method of financing can provide such advantages resale, market research, sponsorship advertising at no additional cost. Other sources of funding have disadvantages, which are limited public information, high risks of investment in projects. However, in crowdfunding through communication with sponsors, obtaining market reviews from them opens unknown previously ways to reduce these risks.
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Tonetto, Mateus Rodrigues, Rudys Rodolfo de Jesus Tavarez, Omar El-Mowafy, et al. "The Effect of Self-adhesive and Self-etching Resin Cements on the Bond Strength of Nonmetallic Posts in Different Root Thirds." Journal of Contemporary Dental Practice 16, no. 2 (2015): 147–53. http://dx.doi.org/10.5005/jp-journals-10024-1652.
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ABSTRACT Purpose The purpose of this study was to evaluate the effect of self-adhesive and self-etching resin cements on the bond strength of nonmetallic posts in different root regions. Materials and methods Sixty single-rooted human teeth were decoronated, endodontically treated, post-space prepared, and divided into six groups. Glass-fiber (GF) posts (Exacto, Angelus) and fiber-reinforced composite (FRC) posts (EverStick, StickTeck) were cemented with self-adhesive resin cement (Breeze) (SA) (Pentral Clinical) and self-etching resin cement (Panavia-F) (SE) (Kuraray). Six 1-mm-thick rods were obtained from the cervical (C), middle (M), and apical (A) regions of the roots. The specimens were then subjected to microtensile testing in a special machine (BISCO; Schaumburg, IL, USA) at a crosshead speed of 0.5 mm/min. Microtensile bond strength data were analyzed with two-way ANOVA and Tukey's tests. Results Means (and SD) of the MPa were: GF/SA/C: 14.32 (2.84), GF/SA/M: 10.69 (2.72), GF/SA/A: 6.77 (2.17), GF/SE/C: 11.56 (4.13), GF/SE/M: 6.49 (2.54), GF/SE/A: 3.60 (1.29), FRC/SA/C: 16.89 (2.66), FRC/SA/M: 13.18 (2.19), FRC/SA/A: 8.45 (1.77), FRC/SE/C: 13.69 (3.26), FRC/SE/M: 9.58 (2.23), FRC/SE/A: 5.62 (2.12). The difference among the regions was statistically significant for all groups (p < 0.05). The selfadhesive resin cement showed better results than the selfetching resin cement when compared to each post (p < 0.05). No statistically significant differences in bond strengths of the resin cements when comparable to each post (p > 0.05). Conclusion The bond strength values were significantly affected by the resin cement and the highest values were found for self-adhesive resin cement. How to cite this article da Silva MB, de Jesus Tavarez RR, de Assis FS, Tonetto MR, Porto TS, Bhandi SH, El-Mowafy O, de Toledo Porto Neto S, Bandeca MC. The Effect of Self-adhesive and Self-etching Resin Cements on the Bond Strength of Nonmetallic Posts in Different Root Thirds. J Contemp Dent Pract 2015;16(2):147-153.
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Gonzalez Rojas, Inigo, Margherita Volpe, Omar Veledar, and Simona Cavallini. "Cascade Funding as an Alternative Funding Source for Innovative Investments." European Conference on Innovation and Entrepreneurship 17, no. 1 (2022): 575–81. http://dx.doi.org/10.34190/ecie.17.1.507.
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Although promoting an innovation ecosystem is a core priority of the European Commission (EC), evidence indicates that innovation within start-ups and Small and medium-sized enterprises (SMEs) is still constrained by the lack of funding opportunities. Consequently, their capability to realise proofs of concepts or launch new risky business lines is limited. This paper aims to comparatively assess cascade funding initiatives against more traditional funding approaches as relevant alternatives for financing innovation. SMEs and start-ups most commonly fund innovative projects through business angels or venture capital. The disadvantages of risk capital include complex administrative procedures, loss of ownership and control over the strategic decision, etc. Other relevant funding is commonly sourced from private bank loans. In addition to discouraging bureaucracy, prior guarantee or collateral required, longer timing and extended terms, these investors are often reluctant to fund innovation due to their high risk. Preference is usually given to safer investments in which assets can be easily valued and sold in case of failure. In addition, financing opportunities from banks do not include an assessment of the return opportunities of innovative businesses. Out of the traditional schemes for financing innovation, cascade funding is a promising alternative, especially in highly innovative sectors. Cascade funding provides small grants issued by the beneficiaries of projects funded by the EC, typically under the Horizon 2020 (H2020) framework (>800 M€ allocated since 2014). As the EC delegates the selection and monitoring of innovative projects to consortiums, the funding is provided via open calls for proposals, which can provide start-ups and SMEs with grants for an experiment between €50,000 and €150,000. This mechanism also enables applicants to benefit from the technical and/or business expertise of leading European enterprises, universities and technology centres. While focusing on exploitable innovation, cascade funding has also proven to be a more agile financing method with respect to the classical ones. Here, DigiFed project is analysed as a Case Study for cascade funding, as it came to allocate over €3M via three open calls for proposals since 2020. Evidence of the advantages of this funding source for innovative businesses with respect to risk capital and bank debt is the core output of this paper.
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Aiudi, G., M. Albrizio, G. De Vico, A. Scirpo, S. Cristarella, and M. Cinone. "261 FERTILITY CONTROL BY GnRH ANALOGUES IN DOGS." Reproduction, Fertility and Development 17, no. 2 (2005): 280. http://dx.doi.org/10.1071/rdv17n2ab261.
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GnRH plays a pivotal role in reproduction by stimulating the release of gonadotrophins. Chemical substitutions in the GnRH molecule lead to analogues possessing antagonist or agonist activity (Paramo RM et al. 1993 J. Reprod. Fertil. Suppl. 47, 387–397). The highly potent agonist analogue, Buserelin, with up to 20 times of potency, by increasing binding affinity, desensitizing competitive receptors, and resisting metabolic degradation, shuts down rather than stimulates reproductive function (Bertschinger HJ et al. 2001 J. Reprod. Fertil. Suppl. 57, 275–283). In man, Buserelin is employed in several gonadal hormone-dependent diseases and for prostatic cancers. We suppress gonadal function in male dogs using Buserelin. Eight intact male German sheep dogs 20 months old were divided into two groups; A, 4 subjects treated for pharmacological castration (Buserelin acetate, 0.3 mg/each, s.c., every 8 h for 30 days) (Suprefact-Aventis Pharma, Italy); B, 4 subjects treated with placebo (NaCl, 0.9%, s.c., every 8 h for 30 days). Plasma testosterone concentrations were measured twice a week by RIA using commercial kits (Coat-A-Count, Los Angeles, USA). Clinical examination of the male genital tract was conducted by ultrasound monitoring. Before and after the pharmacological treatment, semen was collected and evaluated for macroscopic and microscopic parameters. After treatment, testicular specimens were collected by orchiectomy, fixed in Bouin's solution, and embedded in paraffin wax. Thin sections were cut and stained with hematoxylin/eosin. The presence of germ cells (spermatogonia to spermatozoa, Sertoli and Leydig cells number) were analyzed. Randomly selected fields of transverse and longitudinal sections of seminiferous tubules were observed and analyzed using a computer assisted image analyzer (MONO system, Italy). The images acquired were segmented and binarized in order to obtain the masks of the tubular profiles; the mean values of the area, major and minor axes, mean diameter, and perimeter occupied by the testicular tubules were calculated automatically. Data were analyzed by ANOVA test. After Buserelin, all dogs (group A) showed a reduction in testicular and prostatic diameters compared to group B. Azoospermia was observed in group A. Histological examination revealed a statistically significant cell reduction of the germinal line (spermatogonia and spermatocytes, P < 0.05; spermatids and spermatozoa, P < 0.001). GnRH pharmacological treatment induced a cessation of normal spermatogenesis at the spermatocyte level while no statistical difference in morphometric parameters of seminiferous tubules were observed. The basic testosterone level (3.2 ± 1.3 ng/mL) rose to 12 ± 3.7 ng/mL (21° day) and than shut down to 0.5 ± 0.3 ng/mL (30° day), giving a long-term suppression. The present study demonstrates that Buserelin is an anti-fertility agent that gives suppression of reproductive function in male dogs. The method may have a clinical application. The utilization of a Buserelin depot will be a successive step.
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Zekre, F., R. Cimaz, M. Paul, J. L. Stephan, S. Paul, and H. Marotte. "POS0068 HIGH LEVELS OF PORPHYROMONAS GINGIVALIS AND PREVOTELLA INTERMEDIA ANTIBODIES IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 240.2–241. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2222.
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Background:Idiopathic juvenile arthritis (JIA) is a heterogeneous group of pathologies whose origin remains unknown at present (1). They are characterised by a systemic inflammatory and joint disease affecting children under 16 years of age. The current classification groups the different forms of JIA into 7 distinct entities (systemic forms, polyarticular forms with or without rheumatoid factors, oligoarticular forms, inflammatory arthritis associated with enthesopathies (ERA), arthritis associated with psoriasis and unclassifiable arthritis). Exact etiology of JIA is still unknown. To date, the various hypotheses put forward on the occurrence of JIAs integrate the genetic and environmental framework.The link between periodontal disease and rheumatoid arthritis (RA) is largely reported. Recently, Porphyromonas gingivalis (P. gingivalis) infection explained the occurrence of arthritis in rodent and in RA (2). Several studies mention the beneficial effect of P. gingivalis treatment on disease activity.Currently, there are very few studies on the prevalence of P. gingivalis in patients with JIA and the possible involvement of the germ in the development of inflammatory joint diseases in the pediatric population(3)(4).Objectives:The objective of our study is to determine presence of high IgG antibodies against P. gingivalis and Prevotella Intermedia in a cohort of patients with JIA compared to a control population and to determine variation of level according to sub-classes of JIA.Methods:Sera were obtained from 101 patients satisfying the ILAR classification criteria for JIA and in 25 patients with two other dysimmune disorders (type 1 diabetes and juvenile inflammatory bowel disease). Level of IgG antibodies against P. gingivalis and Prevotella Intermedia were obtained by homemade ELISA already used previously (5).Results:In the JIA group, major children were oligarthritis (47.5%), polyarthritis represents 31.7% of JIAs, ERA and systemic forms of JIA are respectively 9 and 11%. For the control group, 10 (40%) children had diabetes and 15 (60%) had IBD.Levels of anti-P. gingivalis anti-Prevotella Intermedia antibodies were higher in AJI group compared at control groups (P<0.01, P<0.05). Theses difference are mainly related to oligoarthritis and ERA subsets for both P. gingivalis and Prevotella Intermedia.Figure 1.Relative titer of antibodies to P. gingivalis and anti Prevotella intermedia. *: P<0.05; **: P<0.01; ***: P<0.001. P. gingivalis (control vs oligoarthritis p= 0.0032. control vs ERA p= 0.0092). Prevotella intermedia (control vs oligoarthritis p= 0.0194. control vs ERA p= 0.0039).Conclusion:We confirmed high level of anti-P. gingivalis and anti-Prevotella intermedia antibodies in JIA compared to other inflammatory disorders. For the first time, we observed that this high level was mainly in oligoarthritis and ERA. Further investigations are required to investigate involvement of oral dysbiosis in AJI pathogenesis. As observed in RA, it could be a new way to integrate in JIA therapy management.References:[1]Thatayatikom A, De Leucio A. Juvenile Idiopathic Arthritis (JIA). StatPearls Publishing; 2020[2]Cheng Z, Meade J, Mankia K, Emery P, Devine DA. Periodontal disease and periodontal bacteria as triggers for rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2017;31(1):19–30.[3]Romero-Sánchez C, Malagón C, Vargas C, Fernanda Torres M, Moreno LC, Rodríguez C, et al. Porphyromonas Gingivalis and IgG1 and IgG2 Subclass Antibodies in Patients with Juvenile Idiopathic Arthritis. J Dent Child Chic Ill. 2017 May 15;84(2):72–9.[4]Lange L, Thiele GM, McCracken C, Wang G, Ponder LA, Angeles-Han ST, et al. Symptoms of periodontitis and antibody responses to Porphyromonas gingivalis in juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2016 Feb 9[5]Rinaudo-Gaujous M, Blasco-Baque V, Miossec P, Gaudin P, Farge P, Roblin X, et al. Infliximab Induced a Dissociated Response of Severe Periodontal Biomarkers in Rheumatoid Arthritis Patients. J Clin Med. 2019 May 26;8(5).Disclosure of Interests:None declared.
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Postma, Hugo J. "De Amsterdamse verzamelaar Herman Becker (ca. 1617-1678); Nieuwe gegevens over een geldschieter van Rembrandt." Oud Holland - Quarterly for Dutch Art History 102, no. 1 (1988): 1–19. http://dx.doi.org/10.1163/187501788x00546.
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AbstractUp to now Herman Becker, one of the people who lent Rembrandt money in the straitened circumstances of the last years of his life, has had a bad press as an art-dealer who owed his wealth and influence to the exploitation of artists (Notes 1, 2). It is now possible to correct this image on the basis of recent research in the Amsterdam archives. Becker was born around 1617 and the supposition that he came from Riga in Latvia is borne out by the facts that he had contacts there, that his father Willem certainly lived there between 1640 and 1650 and that the words 'of or 'to' Riga appear in some documents after his name. His commercial activities certainly go back to 1635 (note 6) and from the earliest records of him in Amsterdam in the 1640s, it is clear that he was a merchant and that he also chartered ships. At this period he further invested money in shares and engaged in a certain amount of moneylending, while he is also mentioned as his father's agent. That financially he was almost certainly in a sound osition by the end of the 1640s is clear from the fact that in 1648 he gave a surety for the merchant Gerard Pelgrom, who was in debt to the Dutch East India Company. That same year he concluded an agreement with the merchant Abraham de Visscher to sell sailcloth for him in Riga. In the 1650s Becker strengthened his financial position and again engaged in moneylending. In 1653 he made a large loan to Johannes de Renialme, an art lover and dealer, and at the time of the latter's death in 1657 his debt to Becker was even larger, while the inventory of his estate mentions nine paintings, including three by Jan Lievens and one by Philips de Koninck, which were mortgaged to Becker along with some jewelry. From the autumn of 1653 Becker spent a considerable time in Riga, but he was certainly back in Amsterdam in 1658. In 1659 he married Anna Maria Vertangen, the widow of his former business contact Gerard Pelgrom, who had died in 1657. This marriage brought Becker two large houses on Keizersgracht, where he moved in June 1659. That he was a Lutheran emerges from records of the baptisms of two of his three children at the Lutheran church in Amsterdam. His wife died shortly after the birth of theyoungest child and was buried in the Oude Kerk on 9 November 1661. By her will Becker was granted usufruct of all her property until his death, on condition that he did not remarry. This increase in his means led to a change of direction in his activities in the 1660s and a growth in the scale and scope of his moneylending. Becker's library (see Appendix I) The list of books in Becker's inventory amounts to 285 titles, a not inconsiderable library by 17th-century standards (Note 26). Their diversity indicates that, though clearly an educated man, he was not a scholar, while they were not arranged under subjects, like a scholar's library, but according to sizes. The presence of works in Latin indicates that Becker must have been educated at a Latin or grammar school, but the large number of German titles point to his coming from the influential German elite, which had long dominated the city government, trade and the guilds in Riga and part of which, like Becker, was Evangelical Lutheran by religion. Books on religion and theology formed a third of the 145 books of which the titles are given, followed by histories and chronicles, classical literature, law, poetry, medicine, physics and astronomy. Contacts with artists In the 1660s Becker continued his shipping interest, but now also invested in property, building a house next to the two others on Keizersgracht in 1665. He also continued to lend money, now for the first time to artists. Rembrandt is known to have owed three sums of money to Becker: 537 guilders borrowed in December 1662 at 5% interest, 450 guilders borrowed in March 1663 against a pledge, and an obligation to Lodewijck van Ludick which was sold to Becker early in 1664 (Notes 31,32). Difficulties over repayment probably arose in the first two instances over disagreement as to the conditions of the loans. On 29 August 1665 the apothecary Abraham Francken declared in a sworn statement that he had ofered the amount due, plus the interest, to Becker at Rembrandt's request, but that Becker had refused to accept it, because Rembrandt first had to finish a Juno and also had to do something else for him. Rembrandt appears to have threatened legal action, but in any case the matter was settled on 6 October 1665 when Becker accepted the payment and returned the pledge, in the form of nine paintings and two (constprint boecken'. What happened to the Juno is not clear. A Juno by Rembrandt is listed in Becker's inventory and it is generally assumed that the Juno in the Armand Hammer Foundation in Los Angeles is the one mentiorted in the statemertt and the inventory. That it is certainly the one in the statement would seem to be justified by the fact that it appears to be unfinished (Notes 37,38). The sale of the obligation to Lodewijck van Ludick to Becker is attested in statements of 31 December 1664 by Abraham Francken and the poet-cum-dyer Thomas Asselyn, the latter declaring that it was bought for textiles to the value of 500 guilders. Three years later Rembrandt had still not paid the debt and the case was brought before an arbitration commission. In the commission's findings of 24 July 1668 the extent of the debt was settled at 1082 guilders, two-thirds of which had to be paid in cash, while the rest was to be paid off in six months in the form of drawings, prints or paintings. Rembrandt also agreed to pay the cash amount within six months while Becker agreed to pay Rembrandt's share of the costs. Rembrandt offered his person and possessions as surety and his son Titus also came forward as guarantor. Whether the debt was ever paid is unclear: Titus died shortly afterwards and Rembrandt about a year later (Note 42). The conditions were actually quite lenient, while Becker's admiration for Rembrandt's art is clear from the fact that he did not mind whether the debt was paid in paintings, prints or drawings. The fourteen works by Rembrandt in Becker's inventory are the largest group by a single master. Obviously Becker had a predilectionfor his work and bought it, but he did not sell it on, as has been suggested (Note 44). Two other artists who borrowed money from Becker were Frederick de Moucheron, who was given an apparently interest-free loan of a hundred guilders in August 1662 and Jan Lievens the Elder, who borrowed four hundred guilders in all between May 1667 and October 1668. By far the greatest number of loans made by Becker date from the period 1674-8, his debtors including Willem Six, Gerrit Uylenburg, Willem Blauw and Abraham van Halmael, as well as the artists Philips de Koninck, Domenicus van Tol and Antony van der Laen. The pledges for the loans are extremely varied, but paintinas often figured among them in the case of both artists and non-artists. In addition Becker also continued to invest in shipping and property. At the end of the summer of 1678 he fell seriously ill and on 16 September he was buried in the Oude Kerk. His estate at his death amounted to 200,000 guilders and it seems fairly clear that in the 1660s and 1670s his activities as a merchant had declined and he had lived mainly off the interest on loarts. Becker's collection of paintings (see Appendix II) Becker appears to have begun collecting pictures around 1660, when the increase in his means allowed it. By comparison with other collections of the day, such as those of Jan van de Cappelle (197 paintings) and Gerrit Uylenburg (95 paintings), his 231 works represent a very sizable holding (Note 63). In the case of 137 of them the name of the painter is known, the best represented artists being Rembrandt (14 works), Jan Lievens the Elder (6), Jan Lievens the Younger (10), Philips de Koninck (7), Frederick de Moucheron (5) and Rubens (3). The collection also included worksfrom Rembrandt's circle (Last-man and Bol) and from Haarlem (Brouwer, Jan de Bray, Goltzius and Cornelis van Haarlem), and in addition work by much earlier artists such as Dürer, Holbein, Lucas van Leyden and Herri met de Bles, as well as ten pictures of Italian origin. Becker certainly acquired paintings through his moneylending and he may further have had agreements like the one with Rembrandt with other artists, these actually being advantageous to both parties. However, his loans to artists were not very numerous, so he must certainly have bought a great many pictures as well. An advertisement discovered in the Oprechte Haerlems Dinsdacgse Courant of 21 March 1679 shows that Becker's art collection was sold separately from the rest of his estate. It also clearly describes him as a collector of many year's standing.No indication whatever has been found that Becker acted as an art-dealer, while his known financial transactions with artists show him to have acted fairly and in no sense can he be said to have exploited them.
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Sarot, Marcel. "Ons lijden en Gods medelijden1Een eerste versie van dit paper heb ik gepresenteerd tijdens een colloquium over het thema ‘Lijden en God’, gehouden aan het HIW te Leuven op 22 mei 1993 ter gelegenheid van een verblijf in Leuven van professor Santiago Sia, Loyola Marymount University, Los Angeles. Gaarne dank ik prof. Sia en de andere aanwezigen voor hun instructieve opmerkingen. Mijn dank gaat tevens uit naar mijn stu-dent-assistente, Tilly Maayen, voor haar hulp bij de voorbereiding van dit manuscript en naar dr. Gijsbert van den Brink en prof.dr. Luco van den Brom, wier commentaar op recente versies van dit paper mij tot aanzienlijke wijzigingen heeft aangezet." NTT Journal for Theology and the Study of Religion 48, no. 2 (1994): 131–40. http://dx.doi.org/10.5117/ntt1994.48.004.saro.
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"One step PCR method for simultaneous detection of HCV RNA and HBV DNA . Dept. of Medicine, Cedars-Sinai Medical Center/UCLA, Los Angeles, CA." Hepatology 18, no. 4 (1993): A151. http://dx.doi.org/10.1016/0270-9139(93)92131-i.
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"Decline of perinuclear antineutrophil cytoplasmic antibody (pANCA) post liver transplant . Dept. of Medicine and Liver Transplantation Program, Cedars-Sinai Medical Center/UCLA, Los Angeles, CA." Hepatology 18, no. 4 (1993): A345. http://dx.doi.org/10.1016/0270-9139(93)92905-f.
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"Altered hepatocyte transport in two rodent models of the acute phase response . University California, Dept. Medicine, San Diego, CA. 1USC School of Medicine, Los Angeles, CA." Hepatology 22, no. 4 (1995): A396. http://dx.doi.org/10.1016/0270-9139(95)95306-x.
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"Chronic cholestatic hepatitis C in immunocompromised patients . Division GI and Liver Diseases, USC School of Medicine, Los Angeles, CA; Dept of Pathology, Rancho Los Amigos Medical Center, Downey, CA." Hepatology 22, no. 4 (1995): A351. http://dx.doi.org/10.1016/0270-9139(95)95128-8.
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Feit, Jonathon, and Christian Witt. "COVID-19 Exposure Tracking Within Public Health & Safety Enterprises:." Online Journal of Public Health Informatics 13, no. 1 (2021). http://dx.doi.org/10.5210/ojphi.v13i1.11484.
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Abstract
 Where there is limited access to COVID-19 tests, or where the results of such tests have been delayed or even invalidated (e.g., California and Utah), there is a need for scalable alternative approaches—such as a heuristic model or “pregnancy test for COVID-19” that can factor in the time denominator (i.e., duration of symptoms). This paper asks whether infection among these public health and safety agencies is a "canary in the coal mine," litmus test, or microcosm (pick your analogy) for the communities in which they operate. Can COVID-19 infection counts and rates be seen “moving around” communities by examining the virus’s effect on emergency responders themselves? The troubling question of emergency responders becoming “human indicator values” is relevant to maintaining the health of Mobile Medicine (EMS and Fire) personnel, as well as Police, who are an under-attended population, because without them our collective resiliency would crash. It has further implications for policies regarding, and investments, in exposure tracking and contact tracing, PPE acquisition, and mental and physical wellness. 
 
 Design: We aggregated data from four (4) different EMS documentation systems across twelve (12) states using the MEDIVIEW BEACON Prehospital Health Information Exchange. We then outputted lists of charts containing critical ICD-10 values that had been identified by the WHO, the CDC, and the Los Angeles County Fire Dept. as inclusion criteria for possible signs, symptoms, and clinical impressions of COVID-19.
 
 Results: Three important results emergency from this study: (1) a demonstration of frequent exposure to possible COVID-19 infection among Mobile Medical (EMS & Fire) care providers in the states whose data were included; (2) a demonstration of the nervousness of the general population, given that calls for help due to possible COVID-19 based on symptomology exceeded the number of responses with a correlating “provider impression” after an informed clinical assessment; and (3) that this study was empowered by a public-private partnerships between a technology startup and numerous public health and public safety agencies, offers a template for success in rapidly implementing research and development collaborations.
 
 Limitations: This study incorporates data from only (a) twelve (12) states, and (b) four (4) Mobile Medical documentation systems. We sought to combat these limitations by ensuring that our sample crosses agencies types, geographies, population demographics, and municipal environments (i.e., rural vs. urban).
 
 Conclusions: Other studies have noted that EMS agencies are tasked with transporting the “sickest of the sick.” We found that PPE is particularly essential where the frequency of encounters between potentially—or actually—infected patients is high, because from Los Angeles County to rural Texas, without sufficient protection, public health and public safety agencies have become microcosms of the communities they are meant to protect. Indeed, data from the first six months of the pandemic in the U.S.A. show that intra-departmental spread is one of (if not the) riskiest sources of infection among Mobile Medical professionals.
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"Role of infiltrating CD4 T cells in the pathogenesis of nonsuppurative destructive cholangitis (NSDC) in murine chronic graft-vs-host disease (CGVHD) . Dept. of Medicine, Cedars-Sinai Medical Center/UCLA, Los Angeles, CA." Hepatology 18, no. 4 (1993): A171. http://dx.doi.org/10.1016/0270-9139(93)92209-i.
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"Orthotopic liver transplantation (OLT) is successful in the management of hepatic disease following bone-marrow transplantation (BMT) . UCLA-Dumont Liver Transplantation Program, Div. of Hem/Onc, and Dept. of Pathology, UCLA School of Medicine, Los Angeles, CA." Hepatology 22, no. 4 (1995): A481. http://dx.doi.org/10.1016/0270-9139(95)95646-8.
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Pollard, Jane, Evelyn Blumenberg, and Stephen Brumbaugh. "Driven to Debt: Social Reproduction and (Auto)Mobility in Los Angeles." Annals of the American Association of Geographers, November 12, 2020, 1–17. http://dx.doi.org/10.1080/24694452.2020.1813541.
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Oliveira, Danila, Mariana Tassinari Caixeta, Fernando Isquierdo de Souza, and Eduardo Passos Rocha. "Restaurações cerâmicas delgadas sobre dentes sem preparo em diferentes regiões dos arcos dentais. Relato de 2 casos clínicos." ARCHIVES OF HEALTH INVESTIGATION 8, no. 1 (2019). http://dx.doi.org/10.21270/archi.v8i1.3140.
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As reforçadas propriedades intrínsecas dos materiais cerâmicos, associados à adesão resinosa fundamentam a desenvoltura de técnicas restauradoras mais simplificadas, conservadoras e sem a necessidade de preparo dental prévio seja em dentição anterior ou posterior. Assim sendo, o trabalho tem como objetivo apresentar dois casos clínicos os quais abordaram a confecção de restaurações delgadas em dissilicato de lítio cimentadas sobre diferentes áreas dos arcos dentários, enfatizando o mesmo protocolo clínico, ou seja, ausência de preparos dentais e consequentemente a cimentação resinosa adesiva das restaurações. Caso Clínico 1: laminados cerâmicos nos elementos 13, 12, 11, 21, 22 e 23; Caso Clínico 2: facetas delgadas sobre os elementos 34, 35, 36 e 37. Ambos os casos clínicos com 1 ano de acompanhamento após a cimentação das restaurações. Conclui-se que houve a recuperação da estética e da função em ambos os casos apresentados e a confiabilidade e o sucesso em longo prazo do protocolo clínico descrito estão diretamente relacionados ao substrato dentário, aos fatores de adesividade dos materiais e as propriedades intrínsecas das cerâmicas.Descritores: Cerâmica; Estética Dentária; Facetas Dentárias; Cimentos de Resina.ReferênciasMurdoch-Kinch CA, McLean ME. Minimally invasive dentistry. J Am Dent Assoc. 2003;134(1):87-95.Ericson D. The concept of minimally invasive dentistry. Dent Update. 2007;34(1):9-10,12-4,17-8.Beier US, Kapferer I, Burtscher D, Dumfahrt H. Clinical performance of porcelain laminate veneers for up to 20 years. Int J Prosthodont. 2012;25(1):79-85.D'Arcangelo C, Vadini M, D'Amario M, Chiavaroli Z, De Angelis F. Protocol for a new concept of no-prep ultrathin ceramic veneers. J Esthet Restor Dent. 2018;30(3):173-79.Vadini M, D'Amario M, De Angelis F, Falco A, D'Arcangelo C. No-prep rehabilitation of fractured maxillary incisors with partial veneers. J Esthet Restor Dent. 2016;28(6):351-58.Molina IC, Molina GC, Stanley K, Lago C, Xavier CF, Volpato CA. Partial-prep bonded restorations in the anterior dentition: long-term gingival health and predictability. A case report. Quintessence Int. 2016;47(1):9-16.Kelly JR, Benetti P. Ceramic materials in dentistry: historical evolution and current practice. Aust Dent J. 2011;56(Suppl 1):84-96.Edelhoff D, Brix O. All-ceramic restorations in different indications: a case series. J Am Dent Assoc. 2011;142(Suppl 2):14S-9S.Miranda ME, Olivieri KA, Rigolin FJ, Basting RT. Ceramic fragments and metal-free full crowns: a conservative esthetic option for closing diastemas and rehabilitating smiles. Oper Dent. 2013;38(6):567-71.Cortellini D, Canale A. Bonding lithium disilicate ceramic to feather-edge tooth preparations: a minimally invasive treatment concept. J Adhes Dent. 2012;14(1):7-10.Wolfart S, Eschbach S, Scherrer S, Kern M. Clinical outcome of three-unit lithium-disilicate glass-ceramic fixed dental prostheses: up to 8 years results. Dent Mater. 2009;25(9):e63-71.Benetti P, Della Bona A, Kelly JR. Evaluation of thermal compatibility between core and veneer dental ceramics using shear bond strength test and contact angle measurement. Dent Mater. 2010;26(8):743-50.Beier US, Kapferer I, Dumfahrt H. Clinical long-term evaluation and failure characteristics of 1,335 all-ceramic restorations. Int J Prosthodont. 2012;25(1):70-8.Veneziani M. Ceramic laminate veneers: clinical procedures with a multidisciplinary approach. Int J Esthet Dent. 2017;12(4):426-48.Anchieta RB, Rocha EP, de Almeida EO, Junior AC, Martini AP. Bonding all-ceramic restorations with two resins cement techniques: a clinical report of three-year follow-up. Eur J Dent. 2011;5(4):478-85.Peumans M, Van Meerbeek B, Lambrechts P, Vanherle G. Porcelain veneers: a review of the literature. J Dent. 2000;28(3):163-77.Barkmeier WW, Erickson RL, Kimmes NS, Latta MA, Wilwerding TM. Effect of enamel etching time on roughness and bond strength. Oper Dent. 2009;34(2):217-22.Esquivel-Upshaw J, Rose W, Oliveira E, Yang M, Clark AE, Anusavice K. Randomized, controlled clinical trial of bilayer ceramic and metal-ceramic crown performance. J Prosthodont. 2013;22(3):166-73.Martin AJ, Buschang PH, Boley JC, Taylor RW, McKinney TW. The impact of buccal corridors on smile attractiveness. Eur J Orthod. 2007;29(5):530-7.Fradeani M. Evaluation of dentolabial parameters as part of a comprehensive esthetic analysis. Eur J Esthet Dent. 2006;1(1):62-9.Borges GA, Sophr AM, de Goes MF, Sobrinho LC, Chan DC. Effect of etching and airborne particle abrasion on the microstructure of different dental ceramics. J Prosthet Dent. 2003;89(5):479-88.Fabianelli A, Goracci C, Bertelli E, Davidson CL, Ferrari M. A clinical trial of Empress II porcelain inlays luted to vital teeth with a dual-curing adhesive system and a self-curing resin cement. J Adhes Dent. 2006;8(6):427-31.Aykor A, Ozel E. Five-year clinical evaluation of 300 teeth restored with porcelain laminate veneers using total-etch and a modified self-etch adhesive system. Oper Dent. 2009;34(5):516-23.Oztürk E, Hickel R, Bolay S, Ilie N. Micromechanical properties of veneer luting resins after curing through ceramics. Clin Oral Investig. 2012;16(1):139-46.Scherrer SS, de Rijk WG, Belser UC, Meyer JM. Effect of cement film thickness on the fracture resistance of a machinable glass-ceramic. Dent Mater. 1994;10(3):172-77.Gresnigt M, Ozcan M. Esthetic rehabilitation of anterior teeth with porcelain laminates and sectional veneers. J Can Dent Assoc. 2011;77:b143.Friedman MJ. A 15-year review of porcelain veneer failure--a clinician's observations. Compend Contin Educ Dent. 1998;19(6):625-8,630,632 passim;quiz 638.Peumans M, De Munck J, Fieuws S, Lambrechts P, Vanherle G, Van Meerbeek B. A prospective ten-year clinical trial of porcelain veneers. J Adhes Dent. 2004;6(1):65-76.Fradeani M, Redemagni M, Corrado M. Porcelain laminate veneers: 6- to 12-year clinical evaluation--a retrospective study. Int J Periodontics Restorative Dent. 2005;25(1):9-17.De Munck J, Van Landuyt K, Peumans M, Poitevin A, Lambrechts P, Braem M et al. A critical review of the durability of adhesion to tooth tissue:methods and results. J Dent Res. 2005;84(2):118-32.
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"ULTRA-HIGH-TECH CANCER THERAPY." Pediatrics 84, no. 4 (1989): A37. http://dx.doi.org/10.1542/peds.84.4.a37.
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Last month, scientists at the Fermi National Accelerator Laboratory here unveiled the first proton beam accelerator built for hospital use. When the machine is ready for operation next year at Loma Linda University Medical Center near Los Angeles, many believe it will prove itself a major breakthrough in the wan on cancer. Others, however, think the proton accelerator is a white elephant. They complain that its untested medical benefits and enormous price make it the ultimate example of medical technology run amok. Some doctors say proton therapy will prove useless in the treatment of most cancers. It is unquestionably the most expensive piece of medical equipment ever built. The cost—$40 million, including the special building needed to house the machine—dwarfs the cost of the next most expensive medical device: the Positron Emitting Tomography scanner, which shows metabolic activity within the brain and can cost about $5 million. Protons were first suggested as a potential cancer therapy in 1946 by Robert Rathbun Wilson, who established the Fermi National Accelerator Laboratory. But it wasn't until the 1970s that patients were first exposed to protons in physics labs at Harvard University, the University of California at Berkeley, at Fermi and at several institutions abroad. In physics labs cluttered with cable and oscilloscopes, physicists have seen some spectacular results using physics research machines moonlighting to treat cancer patients. At Harvard, where 174 patients with malignant tumors at the base of the brain have been treated, the therapy has had an 85% cure rate, compared with 35% cure rate for conventional therapies. (Patients in remission or cancer-free for five years are considered cured.) The beam is virtually useless in cancers that have spread beyond the original site. Such metastacized (sic) cancers account for more [than] two thirds of all malignancies says [one] radiation oncologist. "There's some usefulness, no doubt about it. But the candidates for proton therapy are limited. . . . It won't make a major impact on the cure rates for all cancers. It will make a little dent, but it will cost a lot to make that dent.
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Saadaoui, Amir, Anis Elammari, and Mohamed Kriaa. "Credit rating announcement and bond liquidity: the case of emerging bond markets." Journal of Economics, Finance and Administrative Science, February 16, 2022. http://dx.doi.org/10.1108/jefas-08-2020-0314.
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Purpose This study examines the effect of the informational content of local credit rating announcements in emerging markets on the liquidity of their bond markets. This study analyses the liquidity of bonds in various emerging bond markets using a sample of nine countries: Argentina, Mexico, Peru, Hungary, Poland, Spain, Turkey, Hong Kong and Greece. The sample includes daily data on sovereign bonds that go from July 2009 to July 2017. The main focus is on the period before and after the sovereign debt crisis. This study notes that the bond liquidity is affected due to the sign of the rating granted by the rating agencies for each country. Design/methodology/approach This study aims to question the sources of liquidity problem of sovereign bonds issued by the emerging countries. The study’s database consists of daily data of all nine emerging countries for the period from July 2009 to July 2017. Panel data were collected from the Datastream database. Findings This study first directly tests the information content of bond ratings announcements and their effect on bond market liquidity. Next, the impact of rating changes on sovereign bond liquidity around the rating announcements is studied. Rating changes can affect sovereign bond's price, trading and liquidity around the announcement date. In particular the rating changes that move the bonds out of the investment grade category can elicit selling pressure or even fire sale of the fallen angels. Originality/value This research aims to present data on the prices of sovereign bonds that react to changes in credit rating by studying the price movements around the announcement of changes in credit rating. The literature is very rich in studies on credit rating changes on stocks and corporate bonds, but this study is perhaps the first attempt on sovereign bonds.
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"HCV genotypes: Relevance in long term follow up after alpha IFN therapy for chronic hepatitis C (HCV) . Depts of Medicine and Molecular Microbiology, Washington University School of Medicine, St. Louis, MO and National Genetics Institutes, Los Angeles, CA." Hepatology 22, no. 4 (1995): A494. http://dx.doi.org/10.1016/0270-9139(95)95699-9.
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Dodd, Adam. ""What Happened?"." M/C Journal 1, no. 2 (1998). http://dx.doi.org/10.5204/mcj.1706.
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"And then I ask the question, 'How long have you been doing this?' And it says, 'That knowledge isn't given to you.' And I say, 'Jesus Christ, will you answer a question for the love of God? How long have you been doing this, and stop with those stupid answers.' I'm so pissed off at it. And it sort of just smiles and doesn't answer. And I say, 'Have you been doing this forever?' I don't think it understands forever. And then I ask what it's doing. 'What are you doing?' It wants me to give it my mind, and then it will show me what it's doing. I say, 'No dice, I don't care that much. No thanks, I'm not interested.' It says, 'Why are you afraid? Why are you worried? Don't be afraid.' All the same bullshit that it always wants to give you." -- Abductee 'Karen Morgan', interviewed in David Jacobs's Secret Life "We should learn to live by learning how not to make conversation with the ghost but how to talk with him, with her, how to let them speak or how to give them back speech, even if it is in oneself, in the other, in the other in oneself: they are always there, spectres, even if they do not exist, even if they are no longer, even if they are not yet." -- Jacques Derrida, Spectres of Marx Hundreds of people from all around the world are reporting being abducted by apparently alien beings, taken aboard a UFO or into a profoundly unfamiliar environment, and subjected to bizarre reproductive procedures and quasi-medical examinations. It's usually called alien abduction, and it's becoming increasingly common in western society. Official culture (academics, government, scientific institutions, etc.) have been very slow to acknowledge that anything at all is happening, overlooking the clear implication that even if a lot of people aren't reporting actual experience, that a lot of people believe they are reporting actual experience. The source of this apparent lack of official interest may lie in the undesirability of transgressing the superficial sensationalism that belies the phenomenon's apparent complexity. But what seems unavoidable is the implication that alien abduction represents an unprecedented sociological and psychological phenomenon. Predominantly obfuscating investigation of alien abduction is the absence of a clear mode of approach. The most obvious (and common) place to begin is with the question "is alien abduction real?" -- which quickly proves unproductive, essentially because its premises aren't appropriate. Firstly, it assumes that current definitions of 'real' are both stable and applicable to a hypothetically alien phenomenon. Alien abduction is also commonly deemed impossible a priori; in other words, it's not happening because we 'know' it can't. (Note: this premise embarrassed many French astronomers who for decades, despite villagers' reports, maintained that 'rocks could not fall from the sky'. We now know, despite the astronomers' arrogance, that meteorites do exist.) This is an effect of the dominant ontology -- literally, a reality constructed and reinforced by a minority of powerful members of a culture. Phenomena which threaten the most basic ontological, epistemological and existential premises of this minority are marginalised as tabloid, suppressed, or simply ignored in its hegemonic efforts to maintain power. Secondly, asking if alien abduction is real bypasses the highly problematic trait that connects virtually all abduction cases: the bulk of evidence is in the form of abductees' memories. Roughly 30% of abductions are remembered without the use of hypnosis, and 70% are 'recovered' memories of 'missing time'. (McLeod et al. 156) Most abduction experiences seem to involve complete, or almost complete, erasure of memory of the event. (see Hopkins, Missing Time). Memory itself thus becomes heavily problematised, and no longer reliable. Abduction (if we take any notice of it) causes us to doubt the reality of events that our memories are capable of providing for our perusal, since abductees remember, often very clearly, events which as a culture we generally consider impossible. Conversely, and most provocatively, alien abduction causes us to question the assumed fantasy of events that our memories contain. Vivid dreams are potential abduction experiences. As a society we may stubbornly assume the role of the French astronomers and tell abductees that they are not remembering experience, that their memories are 'false' or have been implanted by hypnotists predisposed to the alien hypothesis. But the abductees, and their memories, do not go away. A conceptualisation of memory that is capable of dealing with alien abduction phenomena should begin by observing that the memorial is intimately linked with the imaginative. It is the retained impression of experience, which is a convergence of imagination (creative thought) and perception (reception of sensory stimuli). Without memory, without the ability to recognise patterns, 'experience' -- meaningful perception -- would not be possible. Experience then, upon which we rely totally to formulate reality, is not possible without memory and imagination. Reality does influence imagination, and vice versa. But imagination is more powerful at the end of the day, since it is always imagination that changes reality. Put simply, discovery is invention. The earth only orbits the sun because enough people imagine (or think or believe) that it does. It only became possible to imagine that the earth orbits the sun, as opposed to the sun orbiting the earth, because of changes that occurred within the culture. Knowledge, despite its claims of universality, is always cultural. The experiences that produce knowledge are always never more than what a culture will allow, can allow. Cultural practice, including the production of knowledge, is and inevitably must be, a restrictive practice. The emergence of postmodern thought is essentially what has allowed an alien abduction phenomenon to begin an existence. Conceptual boundaries which have traditionally precluded such a phenomenon are now being attacked and acknowledged as cultural and therefore subject to change. Postmodern society recognises and appreciates the plasticity and constant change of reality and knowledge, and stresses the priority of concrete experience over fixed abstract principles (Tarnas 395). At its deepest level, alien abduction exposes the arbitrary nature of the reality/non-reality duality, since abduction experiences seem to involve something from non-reality/immateriality (alien beings that walk through walls) entering reality/materiality (its aftereffects are observed in the physical world). Importantly, people are affected not so much by their experience of alien abduction (which are usually forgotten), but by their memories of alien abduction. John E. Mack suggests as a response to this that our use of familiar words like 'happening', 'occurred' and 'real' will themselves have to be thought of differently, and less literally (405). What would have once been interpreted as an inclination towards fantasy, realistic dreams or simply insanity now has the potential to become something more. The memories that so many people are now reporting are not seen as merely memories of dreams, memories of fantasies or memories of episodes of insanity. They are seen as memories of experiences that bridge an objective/subjective dichotomy. They are memories of events that persistently evade complete detection and leave only enough traces in the physical world -- the odd anomalous scar or lesion, and distraught abductees -- to imply that something is happening. But the aliens never land on the White House lawn. Most significantly of all, alien abduction particularly involves that ambiguous bridge between reality and non-reality, perception and imagination -- memory. Memory is the true realm of alien abduction, and we will be forever frustrated if we try to transfer it neatly into other conceptual realms such as 'reality' or 'non-reality', 'perception' or 'imagination'. Alien abduction, like memory, just won't fit into them. It is the hybrid of perception and imagination, the convergence of reality and non-reality, resulting from the privileging of imagination over perception in the formulation of experience. It is the ultimate postmodern myth. References Derrida, Jacques. Spectres of Marx: The State of the Debt, the Work of Mourning, and the New International. London: Routledge, 1994. Harpur, Patrick. Diamonic Reality: Understanding Otherwordly Encounters. London: Penguin, 1994. Hopkins, Budd. Missing Time. New York: Ballantine, 1981. Jacobs, David M. Secret Life: Firsthand Documented Accounts of UFO Abductions. New York: Simon and Schuster, 1992. Mack, John E. Abduction: Human Encounters with Aliens. London: Simon and Schuster, 1995. McLeod, Caroline C., Barbara Corbisier, and John E. Mack. "A More Parsimonious Explanation for UFO Abduction." Psychological Inquiry 7.2 (1996): 156-168. Tarnas, Richard. The Passion of the Western Mind: Understanding the Ideas That Have Shaped Our World View. New York: Ballantine, 1991. Thompson, Keith. Angels and Aliens: UFOs and the Mythic Imagination. New York: 1993. Citation reference for this article MLA style: Adam Dodd. "'What Happened?' Deconstructing Memories of Alien Abduction." M/C: A Journal of Media and Culture 1.2 (1998). <http://www.uq.edu.au/mc/9808/alien.php>. Chicago style: Adam Dodd, "'What Happened?' Deconstructing Memories of Alien Abduction," M/C: A Journal of Media and Culture 1, no. 2 (1998), <http://www.uq.edu.au/mc/9808/alien.php>. APA style: Adam Dodd. (1998) "What happened?" Deconstructing memories of alien abduction. M/C: A Journal of Media and Culture 1(2). <http://www.uq.edu.au/mc/9808/alien.php> ([your date of access]).