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Journal articles on the topic 'Lost eyelashes'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Dedurenko, V. I. "A simple method of removing eyelashes from the anterior chamber of the eye." Kazan medical journal 67, no. 3 (1986): 213–14. http://dx.doi.org/10.17816/kazmj70084.

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After sustained penetrating wounds of the cornea and corneoscleral region, cilia are sometimes found in the anterior chamber of the eye that were not found and removed during the primary surgical treatment of the wound. They are usually extracted with forceps through a limbal incision with a conjunctival flap. The technique of this operation is complicated, because it is necessary to manipulate under the conditions of the emptied anterior chamber of the eye; in addition, the cilia may be lost in the iris stroma. An operating microscope and micro instrumentation are required for the operation.

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2

Murugesan, Sindhuja, Premjith Muraleedharan, Mridhula Sunil, and Shahseena Abdulla. "“From Lush to Lost: Eyelashes Finding a Home in the Conjunctiva” – A Case Report of Conjunctival Dermoid." TNOA Journal of Ophthalmic Science and Research 63, no. 2 (2025): 215–16. https://doi.org/10.4103/tjosr.tjosr_49_25.

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We report an unusual case of conjunctival dermoid which presented with hair growth in the inferior fornix. Case report: An 8-year-old girl presented to us with chronic irritation and foreign body sensation in her left eye which was treated at multiple hospitals as allergic conjunctivitis. On examination, there was a tuft of hair growth in the inferior conjunctival fornix. Excision biopsy was performed, and the histopathology report concluded to be a conjunctival dermoid. Post-operatively, there was no recurrence noted at 6 months. Conjunctival dermoid can also present as a conjunctival hair fo

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3

Ringoringo, Harapan Parlindungan. "Alopecia Totalis in a Five-Year-Old Boy: A Case Report." Open Access Macedonian Journal of Medical Sciences 10, no. C (2022): 42–45. http://dx.doi.org/10.3889/oamjms.2022.8078.

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Background: Alopecia totalis (AT) represent the severe form of alopecia areata with a worse prognosis. In population the prevalences of alopecia totalis, is 0,08%. This study shows that Prosential, minoxidil 2% and clobetasol propionate 0.05% therapy for hair loss could be considered Case presentation: A 5-year-old boy weighing 13.4 kg came to the hospital complaining of hair loss all over his head, bald since two months before. The eyebrows, eyelashes, and nose hairs were also missing. The diagnosis is alopecia totalis. The patient was given Prosential therapy for four month

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4

DUMAN, Nilay, Reşat DUMAN, and Rahmi DUMAN. "Eyelashes: Anatomical and Physiological Features, Eyelash Loss and Trichomegaly: Review." Turkiye Klinikleri Journal of Ophthalmology 24, no. 3 (2015): 168–77. http://dx.doi.org/10.5336/ophthal.2015-43769.

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5

Venneuguès, Rowena Vicencio, Abby Macbeth, and Nick J. Levell. "Dramatic and persistent loss of eyelashes." JRSM Open 6, no. 5 (2015): 205427041557977. http://dx.doi.org/10.1177/2054270415579779.

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6

Jordan, David. "Eyelash Loss." Seminars in Plastic Surgery 21, no. 1 (2007): 032–36. http://dx.doi.org/10.1055/s-2007-967745.

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7

Matsuura, Hiroki, and Yu Suganami. "Hypothyroidism, eyelash loss." Cleveland Clinic Journal of Medicine 87, no. 12 (2020): 717. http://dx.doi.org/10.3949/ccjm.87a.20009.

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8

Lipoff, Jules B., Katherine T. Steele, and Neha Jariwala. "Eyebrow and Eyelash Loss." JAMA 317, no. 1 (2017): 81. http://dx.doi.org/10.1001/jama.2016.17688.

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9

Draelos, Zoe Kececioglu, and R. Patrick Yeatts. "Eyebrow Loss, Eyelash Loss, and Dermatochalasis." Dermatologic Clinics 10, no. 4 (1992): 793–98. http://dx.doi.org/10.1016/s0733-8635(18)30313-9.

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10

Jordan, David R., Nina Ahuja, and Lucie Khouri. "Eyelash Loss Associated With Hyperthyroidism." Ophthalmic Plastic & Reconstructive Surgery 18, no. 3 (2002): 219–22. http://dx.doi.org/10.1097/00002341-200205000-00013.

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11

Cathcart-Rake, Elizabeth, Charles L. Loprinzi, Fergus Couch, et al. "Abstract P4-10-11: Eyebrow/eyelash loss among survivors." Cancer Research 82, no. 4_Supplement (2022): P4–10–11—P4–10–11. http://dx.doi.org/10.1158/1538-7445.sabcs21-p4-10-11.

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Abstract Background: Eyebrow and eyelash loss are widely recognized as consequences of some chemotherapies, but prevalence and predictors are understudied. The purpose of this study was to evaluate real world experiences of eyebrow and eyelash loss during treatment for breast cancer. Methods: Breast cancer survivors participating in the ongoing prospective Mayo Clinic Breast Disease Registry (MCBDR) were mailed a survey one year after diagnosis. Respondents were asked to recall their severity of eyebrow and eyelash loss since diagnosis, measured from “no loss” to “a little loss” to “a lot of l

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12

Wachsmuth, Rachel, and Mark Wilkinson. "Loss of eyelashes after use of a tinting mascara containing PPD." Contact Dermatitis 54, no. 3 (2006): 169–70. http://dx.doi.org/10.1111/j.0105-1873.2005.0739b.x.

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13

Succurro, Elena, Caterina Palleria, Mariafrancesca Ruffo, Raffaele Serra, Franco Arturi, and Luca Gallelli. "Loss of Eyebrows and Eyelashes During Concomitant Treatment with Sitagliptin and Metformin." Current Drug Safety 12, no. 1 (2017): 10–12. http://dx.doi.org/10.2174/1574886311666161014125536.

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14

Nezafati, S., S. Rahimi, and H. Mohseni. "Temporary eyelash loss following dental treatment." International Journal of Oral and Maxillofacial Surgery 39, no. 11 (2010): 1142–44. http://dx.doi.org/10.1016/j.ijom.2010.04.052.

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15

Premji, Sarah, Kathryn Ruddy, Nicole Larson, et al. "Abstract PO5-12-10: Eyebrow and eyelash loss in breast cancer survivors." Cancer Research 84, no. 9_Supplement (2024): PO5–12–10—PO5–12–10. http://dx.doi.org/10.1158/1538-7445.sabcs23-po5-12-10.

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Abstract Background: Eyebrow and eyelash loss, known as madarosis, can occur secondary to breast cancer-directed therapy. However, the incidence and predictors of this phenomenon are not well-known. The purpose of this study is to ascertain the proportion of breast cancer survivors who experience madarosis, potential contributing factors to eyebrow and eyelash loss, and associations between this symptom and mental health. Methods: Breast cancer survivors were invited to participate in an ongoing longitudinal cohort study, the Mayo Clinic Breast Disease Registry (MCBDR), after having been seen

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16

Rose, Lucy, Aliza Khuhro, Abena Minta, et al. "Eyebrow and Eyelash Loss in Patients With Cancer." Journal of Drugs in Dermatology 23, no. 5 (2024): 327–31. http://dx.doi.org/10.36849/jdd.8003.

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17

Bjekić, Milan. "Diffuse Hair Loss in Secondary Syphilis in HIV Positive Man: Case Report." Acta Facultatis Medicae Naissensis 29, no. 4 (2012): 193–97. http://dx.doi.org/10.2478/v10283-012-0027-1.

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SUMMARY Hair loss is not a common feature of secondary syphilis. There are two types of syphilitic alopecia: “symptomatic” type where hair loss is associated with other symptoms of secondary syphilis, and “essential” alopecia that is either patchy (“moth-eaten” type), diffuse pattern with a generalized thinning of the scalp hair, or a combination of both without any other mucocutaneous signs of syphilis. This article presents a case of syphilitic alopecia in a 30-year-old homosexual man. The patient had diffuse non-scarring alopecia of his scalp and loss of eyelashes and eyebrows. A macular ra

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18

Lim, T. A., and K. Inbasegaran. "Predicted effect compartment concentration of thiopental at loss of eyelash reflex." British Journal of Anaesthesia 86, no. 3 (2001): 422–24. http://dx.doi.org/10.1093/bja/86.3.422.

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19

Soyer, E., O. M. Orenay, and A. B. Aksakal. "An exceptional case with unilateral eyelash loss due to intracranial lesion." Journal of the European Academy of Dermatology and Venereology 31, no. 3 (2016): e174-e175. http://dx.doi.org/10.1111/jdv.13893.

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20

Rivera Pérez de Rada, P., J. Rivera Salazar, R. Juárez Tosina, and J. M. Olalla Gallardo. "Eyelash loss in frontal fibrosing alopecia: Microscopic features of two cases." Journal Français d'Ophtalmologie 44, no. 1 (2021): 48–52. http://dx.doi.org/10.1016/j.jfo.2020.03.022.

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21

Honma, Masaru, Tomoe Shimamura, Shigetsuna Komatsu, Masako Minami-Hori, Ranko Hinooka, and Hajime Iizuka. "Eyelash trichomegaly: Report of a case following diffuse hair loss associated with transient malnutrition." Journal of Dermatology 40, no. 9 (2013): 759–60. http://dx.doi.org/10.1111/1346-8138.12223.

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22

International, Journal of Medical Science and Innovative Research (IJMSIR). "A Comparative Study between Propofol and Etomidate for Induction During General Anaesthesia." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 2 (2024): 132–40. https://doi.org/10.5281/zenodo.15378665.

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<strong>Abstract</strong> <strong>Background:</strong> Propofol and Etomidate are non-barbiturate inducing agents. These drugs have different induction characteristics and recovery profiles. Propofol causes pain at the injection site, and hypotension but has clear-headed recovery whereas Etomidate is cardio-stable but can cause myoclonus. <strong>Objective:</strong> The purpose of this study is to compare Propofol and Etomidate on induction characteristics i.e. loss of eyelash reflex, pain at the injection site, myoclonus, hemodynamic parameters and recovery profile. <strong>Methods:</strong>

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23

King, Brett, Manabu Ohyama, and Arash Mostaghimi. "32237 Clinician and patient evaluation of improvement for eyebrow and eyelashes hair loss during baricitinib phase 3 trials BRAVE-AA1 and BRAVE-AA2." Journal of the American Academy of Dermatology 87, no. 3 (2022): AB33. http://dx.doi.org/10.1016/j.jaad.2022.06.165.

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24

Ahluwalia, Gurpreet S. "Safety and Efficacy of Bimatoprost Solution 0.03% Topical Application in Patients with Chemotherapy-Induced Eyelash Loss." Journal of Investigative Dermatology Symposium Proceedings 16, no. 1 (2013): S73—S76. http://dx.doi.org/10.1038/jidsymp.2013.30.

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25

Mi, W. D., T. Sakai, A. Matsuki, and H. Zhang. "INTERACTION BETWEEN PROPOFOL AND FENTANYL FOR INDUCING UNCONSCIOUSNESS AND LOSS OF EYELASH REFLEX-MONITORING WITH EEG PARAMETERS." Anesthesiology 89, Supplement (1998): 924A. http://dx.doi.org/10.1097/00000542-199809160-00028.

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26

Shapiro, Jerry, Justin Ko, Alexander Egeberg, et al. "41247 Baseline distribution of eyebrow and eyelash loss by severity of scalp hair loss in phase 3 trials of baricitinib for alopecia areata." Journal of the American Academy of Dermatology 89, no. 3 (2023): AB127. http://dx.doi.org/10.1016/j.jaad.2023.07.511.

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27

Susilo, Rivani, Lisda Damayanti, and Vita Mulya Passa Novianti. "Prosthetic rehabilitation of anophthalmic ocular sinistra and phthisis bulbi ocular dextra: a case report." Padjadjaran Journal of Dentistry 37, no. 1 (2025): 36–43. https://doi.org/10.24198/pjd.vol37no1.59219.

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Introduction: Loss of an eyeball due to enucleation or phthisis bulbi results in functional deficiency and facial deformities. This condition can cause significant psychological distress, especially if it results from unexpected infections or trauma. Case Report: A 30-year-old male patient presented to the Prosthodontic Clinic at Universitas Padjadjaran's Dental Hospital with complaints of low self-confidence due to his eye condition. The patient lost his left eye in childhood due to trauma and subsequently underwent surgical removal. Examination revealed a healthy conjunctiva with no signs of

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28

Mostaghimi, Arash, Cheshana Kindred, Pedro Herranz Pinto, et al. "Efficacy of Ritlecitinib in Patients with Alopecia Areata by Extent of Hair Loss: Results from the Phase 2b/3 and Phase 3 ALLEGRO Clinical Trials." SKIN The Journal of Cutaneous Medicine 8, no. 6 (2024): s468. http://dx.doi.org/10.25251/skin.8.supp.468.

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Introduction: Ritlecitinib, a dual JAK3/TEC family kinase inhibitor, demonstrated efficacy and safety in patients ≥12 years old with AA and ≥50% scalp hair loss in the phase 2b/3 ALLEGRO study. This post hoc, pooled analysis of the ALLEGRO-2b/3 and phase 3 ALLEGRO-LT studies evaluated the efficacy of ritlecitinib in patients with alopecia areata (AA) by extent of baseline scalp hair loss through Month 24. Methods: Patients aged ≥12 years with AA and ≥50% scalp hair loss who received ritlecitinib 50 mg daily in ALLEGRO-2b/3 and rolled over to ALLEGRO-LT (continued to receive 50 mg) were include

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29

Fatahillah Ramdhan, R. Adji, Sani Susanto, and Franciscus Rian Praktikto. "Feasibility Analysis of Capacity Building at CV X Bintaro Branch." Jurnal Improsci 2, no. 3 (2024): 140–55. https://doi.org/10.62885/improsci.v2i3.557.

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CV X is a company engaged in beauty services such as nail and eyelash treatment. CV X has a problem: a lack of salon capacity due to the high customer demand. This caused lost sales of IDR 188,597,000 in 2022 because customers were rejected when they wanted to book due to full capacity. Therefore, the owner of CV X plans to increase the capacity of the Bintaro branch to minimize the occurrence of lost sales, which can cause significant losses. To improve this capacity, an analysis is needed to precede it so that CV X can determine whether this capacity-building plan is feasible from various as

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30

Stroi, O. А., Т. А. Кyian, N. I. Balatska, L. O. Levadna, and G. E. Kozynkevych. "Clinical case of alopecia totalis in pediatric practice." Modern pediatrics. Ukraine, no. 4(132) (May 28, 2023): 99–103. http://dx.doi.org/10.15574/sp.2023.132.99.

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Alopecia (baldness) is a pathological hair loss. A chronic relapsing course leads to a violation of the emotional sphere of the child, worsens the quality of life. Alopecia is considered autoimmune, since it is characterized by hair loss due to lymphocytic infiltration around the hair follicles. It can be secondary as a result of infectious and inflammatory processes. Purpose - is to conduct own clinical observation of a child with total alopecia to increase the awareness of doctors about this pathology in children. Clinical case. The article presents a clinical case of total alopecia in an 11

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31

Senna, Maryanne M., Ohsang Kwon, Bianca Maria Piraccini, et al. "33774 Baricitinib results in eyebrow and eyelash growth in patients with alopecia areata who do not achieve 20% or less scalp hair loss." Journal of the American Academy of Dermatology 87, no. 3 (2022): AB144. http://dx.doi.org/10.1016/j.jaad.2022.06.610.

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32

Ko, Justin, Amy McMichael, Antonella Tosti, et al. "Agreement Between Patient and Physician Assessment of Eyebrow and Eyelash Hair Loss in Two Phase 3 Trials Evaluating Baricitinib in Patients with Severe Alopecia Areata." SKIN The Journal of Cutaneous Medicine 7, no. 6 (2023): s295. http://dx.doi.org/10.25251/skin.7.supp.295.

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33

King, Brett, Arash Mostaghimi, Manabu Ohyama, et al. "52709 Patient-Reported Outcomes for Scalp, Eyebrow and Eyelash Hair Loss in Patients with Severe Alopecia Areata Treated with Baricitinib: 152 Week Results from two Phase 3 Clinical Trials." Journal of the American Academy of Dermatology 91, no. 3 (2024): AB69. http://dx.doi.org/10.1016/j.jaad.2024.07.282.

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34

Alma, Dema. "The Autobiographical and National Yeast of E. Halili's Poetry under Narrative Interpretive Observation." Beder Journal of Educational Sciences Volume 26(2) (June 22, 2023): 107–23. https://doi.org/10.5281/zenodo.8070040.

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<strong>Abstract</strong> Albanian is spoken and written in two main dialects: The tosk and the geg ones. The tosk is used in South Albania and geg in the north Albania. The national literary tradition recognizes achievements in both dialects so much so that the Tosk dialect lies at the core of the construction of what is called the official Albanian language. The geg dialect is a dialect in which important figures and personalities of Albanian culture, art and literature have written, leaving a rich and very enviable fund of literary critics of art and moreover of scholars of language and dia

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35

Dieu, D. "Replaced Loss of Upper Eyelid by Frontal Skin Graft." September 15, 2017. https://doi.org/10.19070/2379-156X-1700018.

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Loss of an upper eyelid can arise through trauma in local/remote area. This condition in which the eye cannot be closed is severe affected patient’s vision with unavailable treatment. The patient should be transferred to tertiary health care level for treatment. We introduce the simple surgical techniques that can be performed at the second health care level under local anesthesia without the need for expensive technical equipment. This is an auto frontal skin grafting-single staged procedure on the course of hospital administration for correction of upper lid which was cut out off due to trau

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36

Starace, Michela, Stephano Cedirian, Aurora M. Alessandrini, et al. "Impact and Management of Loss of Eyebrows and Eyelashes." Dermatology and Therapy, May 15, 2023. http://dx.doi.org/10.1007/s13555-023-00925-z.

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37

Jamison, Aaron, Linda Okafor, Katja Ullrich, Vivian Schiedler, and Raman Malhotra. "Do Prostaglandin Analogue Lash Lengtheners Cause Eyelid Fat and Volume Loss?" Aesthetic Surgery Journal, June 14, 2022. http://dx.doi.org/10.1093/asj/sjac156.

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Abstract Background Prostaglandin analogues (PGAs; a first-line anti-glaucoma treatment) have been re-marketed as popular eyelash lengthening serums due to their lash lengthening and thickening side-effects. Periorbital volume loss is now a well-established side-effect of topical PGAs used to treated glaucoma (prostaglandin-associated periorbitopathy [PAP]) but has not, to date, been listed as a potential side-effect of lash lengthening serums containing PGA. Objectives To identify whether periorbital fat/volume loss is seen in users of prostaglandin analogue lash lengtheners. Methods A case r

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38

Zhang, Li-wen, Juan Wu, Tao Chen, and Rong-hua Xu. "Unilateral eyelid itching with eyelash loss after travelling." Journal of Travel Medicine, March 22, 2023. http://dx.doi.org/10.1093/jtm/taad025.

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Highlight Tinea blepharitis is a rare dermatophyte infection. The characteristic broken eyelash is an important diagnostic clue by trichoscopy or slit lamp examination. Other clinical clues suggesting dermatophytosis include pruritic scaly annular erythema and a history of recent contact with pets.

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39

Palacios-Bayona, Karen Lorena, and Catalina Tobón-Ospina. "Eyelash Loss: An Unusual Manifestation of Uncontrolled Hypothyroidism." Cureus, May 2, 2024. http://dx.doi.org/10.7759/cureus.59551.

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40

Norton, Daniel J., and Carolyn Cates. "Eyelash Loss Secondary to Escitalopram But Not to Sertraline." Primary Care Companion For CNS Disorders, May 19, 2016. http://dx.doi.org/10.4088/pcc.15l01887.

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41

Wondimu, Bitania. "Progressive Eyelash Loss and Scale of the Right Eyelid." Cutis 114, no. 1 (2024). http://dx.doi.org/10.12788/cutis.1052.

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42

Glennie, Lorraine, Marta Codina Solà, Mar Xunclà та ін. "A novel FAM83G variant from palmoplantar keratoderma patient disrupts WNT signalling via loss of FAM83G-CK1α interaction". Open Biology 14, № 7 (2024). http://dx.doi.org/10.1098/rsob.240075.

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Palmoplantar keratoderma (PPK) is a multi-faceted skin disorder characterized by the thickening of the epidermis and abrasions on the palms and soles of the feet. Among the genetic causes, biallelic pathogenic variants in the FAM83G gene have been associated with PPK in dogs and humans. Here, a novel homozygous variant (c.794G>C, p.Arg265Pro) in the FAM83G gene, identified by whole exome sequencing in a 60-year-old female patient with PPK, is reported. The patient exhibited alterations in the skin of both hands and feet, dystrophic nails, thin, curly and sparse hair, long upper eyelid eyela

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43

Fu, Jennifer, and Carolyn Goh. "Beyond Universalis: eyebrow and eyelash loss in patients with alopecia areata." British Journal of Dermatology, April 11, 2025. https://doi.org/10.1093/bjd/ljaf139.

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44

Jiang, Shangxuan, Zhuolun Hao, Wenli Qi, Zhenxing Wang, Muran Zhou, and Nengqiang Guo. "The efficacy of topical prostaglandin analogs for hair loss: A systematic review and meta-analysis." Frontiers in Medicine 10 (March 14, 2023). http://dx.doi.org/10.3389/fmed.2023.1130623.

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BackgroundProstaglandin analogs have been found to have more versatile uses: treatment of open-angle glaucoma, high intraocular pressure, vitiligo, and other treatments. And prostaglandin analogs have been found to have an important role in the hair growth cycle. However, prostaglandin analogs have not been sufficiently studied for hair (including hair, eyelashes, and eyebrows) regeneration. In this study, a systematic review and meta-analysis of topical prostaglandin analogs on hair loss was performed.ObjectiveThe purpose of this meta-analysis is to determine the efficacy and safety of topica

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45

Mumford, Blake Phillip, Samantha Eisman, and Leona Yip. "Acquired causes of eyebrow and eyelash loss: A review and approach to diagnosis and treatment." Australasian Journal of Dermatology, November 2022. http://dx.doi.org/10.1111/ajd.13947.

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46

González‐Escalante, Ana Paulina, León Felipe Ruiz‐Arriaga, Roberto Arenas, Brenda Alejandra Hermosillo‐Cardoza, Nixma Eljure‐López, and Carlos Enrique Atoche‐Dieguez. "Answer to: Acquired causes of eyebrow and eyelash loss: A review and approach to diagnosis and treatment." Australasian Journal of Dermatology, October 10, 2023. http://dx.doi.org/10.1111/ajd.14171.

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47

Ricar, Jan, Petra Cetkovska, Maria Hordinsky, and Renata Ricarova. "Topical bimatoprost in the treatment of eyelash loss in alopecia totalis and universalis: A prospective, open‐label study." Dermatologic Therapy, March 18, 2022. http://dx.doi.org/10.1111/dth.15438.

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48

-, Abhay Paul Baghwar, and Arun Chandran Ramachandran -. "Quality of Life in Patients Living with Andro-gentic Alopecia: A Cross Sectional Observational Study." International Journal For Multidisciplinary Research 6, no. 5 (2024). http://dx.doi.org/10.36948/ijfmr.2024.v06i05.27254.

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Alopecia is a chronic dermatological disorder in which people lose some or all of the hair on their head and sometimes on their body as well. It is a chronic inflammatory disease that affects the hair follicles. It is neither life threatening nor painful, though there can be irritation of the skin, as well as physical problems resulting from the loss of eyelashes and eyebrows.This study aim to improve the quality of life and prescription pattern in androgenic alopecia. The goal of the study was to assess the quality of life of subjects living androgenic alopecia and to assess the prescription

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49

Yang, Hua, Hui-Min Deng, Hai-Yan Chen, et al. "The Impact of Age on Propofol Requirement for Inducing Loss of Consciousness in Elderly Surgical Patients." Frontiers in Pharmacology 13 (March 28, 2022). http://dx.doi.org/10.3389/fphar.2022.739552.

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It is generally accepted that geriatric patients are more sensitive to propofol than adults; thus, a dose-adjusted propofol is recommended for these patients during the induction of anesthesia. However, for patients aged 75 years and over, established guidelines for propofol induction doses do not provide dose references. To this end, we observed 80 surgical patients (female 39, male 41, American Society of Anesthesiologists physical status score I ∼ II) to access the appropriate dose of propofol for inducing loss of consciousness (LOC). Accordingly, patients were subdivided into group A (20 p

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"Neoadjuvant Chemotherapy Can Decrease the EC50 of Propofol with Effect-Site for Inducing the Loss of Consciousness in Patients with Breast Cancer: A Prospective Study." Journal of Anesthesia & Pain Medicine 2, no. 1 (2017). http://dx.doi.org/10.33140/japm/02/01/00005.

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Background: Neoadjuvant chemotherapy has many advantages, including shrinking the tumor volume, reducing the scope of operation, decreasing the degree of trauma and providing evidence for postoperative chemotherapy. However, a certain degree changes of physiological are associated with neoadjuvant chemotherapy. Therefore, we suspect that the sensitive to general agents would be also changed after neoadjuvant chemotherapy. This study aimed to determine the minimum effective concentration represented by the EC50 of propofol for inducing loss of consciousness (LOC). Methods: Sixty patients with b

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