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1

Alten, Jeffrey A., and Michael Gaies. "Defining Low Cardiac Output Syndrome." Pediatric Critical Care Medicine 18, no. 1 (2017): 85–87. http://dx.doi.org/10.1097/pcc.0000000000000989.

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2

Wezel, Harry Van. "Low Cardiac Output Syndrome Revisited." Seminars in Cardiothoracic and Vascular Anesthesia 7, no. 1 (2003): 1. http://dx.doi.org/10.1177/108925320300700101.

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3

Merekin, D. N., V. V. Lomivorotov, S. M. Efremov, M. Yu Kirov, and V. N. Lomivorotov. "Low cardiac output syndrome in cardiac surgery." Almanac of Clinical Medicine 47, no. 3 (2019): 276–97. http://dx.doi.org/10.18786/2072-0505-2019-47-035.

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4

Lomivorotov, Vladimir V., Sergey M. Efremov, Mikhail Y. Kirov, Evgeny V. Fominskiy, and Alexander M. Karaskov. "Low-Cardiac-Output Syndrome After Cardiac Surgery." Journal of Cardiothoracic and Vascular Anesthesia 31, no. 1 (2017): 291–308. http://dx.doi.org/10.1053/j.jvca.2016.05.029.

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5

Jones, Bryn, Mark Hayden, John F. Fraser, and E. Janes. "Low cardiac output syndrome in children." Current Anaesthesia & Critical Care 16, no. 6 (2005): 347–58. http://dx.doi.org/10.1016/j.cacc.2006.02.011.

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6

Amabili, Philippe, Sabeha Benbouchta, Laurence Roediger, et al. "Low Cardiac Output Syndrome After Adult Cardiac Surgery." Anesthesia & Analgesia 126, no. 5 (2018): 1476–83. http://dx.doi.org/10.1213/ane.0000000000002605.

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7

Poelaert, Jan, Carl Roosens, Luc Foubert, Filip De Somer, Frank Caes, and Francis A. Colardyn. "Continuous cardiac output monitoring in postcardiotomy low output syndrome." Journal of Cardiothoracic and Vascular Anesthesia 9, no. 3 (1995): 348–49. http://dx.doi.org/10.1016/s1053-0770(05)80350-7.

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8

Bechri, Ibrahim, Ali Derkaoui, Abdelkarim Shimi, and Mohammed Khatouf. "Low cardiac output syndrome after cardiac surgery: A retrospective analysis." INTERNATIONAL JOURNAL OF MEDICINE AND MEDICAL RESEARCH 9, no. 1 (2023): 6–14. http://dx.doi.org/10.61751/ijmmr.2413-6077.2023.1.06.

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Low cardiac output syndrome is a prevalent complication observed after cardiac surgery, related to elevated rates of mortality and morbidity. The study aimed to pinpoint independent risk factors for low cardiac output through the analysis of post-cardiac surgery data. This is a single-centre, two-year retrospective study from January 2021 to December 2022, including all patients admitted to the A1 general intensive care unit for postoperative management of cardiac surgery. Variables from preoperative, intraoperative, and postoperative data were collected and evaluated with the statistical pack
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9

Fita, G., C. Gomar, M. J. Jimenez, M. Pacheco, J. Mulet, and M. A. Nalda. "Amrinone in perioperative low cardiac output syndrome." Acta Anaesthesiologica Scandinavica 34, no. 6 (1990): 482–85. http://dx.doi.org/10.1111/j.1399-6576.1990.tb03128.x.

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10

Cuadrado, Angel R. "Management of Postoperative Low Cardiac Output Syndrome." Critical Care Nursing Quarterly 25, no. 3 (2002): 63–71. http://dx.doi.org/10.1097/00002727-200211000-00008.

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11

Massé, Linda, and Marie Antonacci. "Low Cardiac Output Syndrome: Identification and Management." Critical Care Nursing Clinics of North America 17, no. 4 (2005): 375–83. http://dx.doi.org/10.1016/j.ccell.2005.07.005.

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12

Levy, Jerrold H., and J. Earl Wynands. "Management of surgical low cardiac output syndrome." Journal of Cardiothoracic Anesthesia 4, no. 6 (1990): 1. http://dx.doi.org/10.1016/0888-6296(90)90224-4.

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13

Doyle, Anthony R., Achal K. Dhir, Anthony H. Moors, and Raymond D. Latimer. "Treatment of perioperative low cardiac output syndrome." Annals of Thoracic Surgery 59 (February 1995): S3—S11. http://dx.doi.org/10.1016/0003-4975(94)00916-u.

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14

Rana, KB, A. Ansari, P. Sharma, L. Yadav, and A. Shahbaz. "Frequency of Low Cardiac Output Syndrome Following on Pump Coronary Artery Bypass Grafting Surgery and it’s Association with Degree of Pre-operative Left Ventricular Dysfunction." Kathmandu University Medical Journal 21, no. 1 (2023): 79–84. https://doi.org/10.3126/kumj.v21i1.80579.

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Background Low cardiac output syndrome (LCOS) is a serious complication after coronary artery bypass grafting (CABG) surgery. It is associated with 10 times to 17 times increase in mortality and markedly increase morbidity. Objective To find out the frequency of Low cardiac output syndrome following on pump coronary artery bypass grafting surgery, to determine the association of Low cardiac output syndrome with degree of pre-operative left ventricular dysfunction and to compare in hospital outcomes of coronary bypass surgery with and without low cardiac output syndrome. Method This prospective
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15

Trung, Hoang Van, Pham Thi Thu Trang, Dam Hai Son, and Nguyen Tran Thuy. "Low cardiac output syndrome after cardiac surgery with extracirculatory at cardiovascular center, E hospital." Tạp chí Phẫu thuật Tim mạch và Lồng ngực Việt Nam 42 (July 25, 2023): 48–54. http://dx.doi.org/10.47972/vjcts.v42i.901.

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Background: Low cardiac output syndrome is one of the most severe complications after cardiac surgery, associated with 38% mortality, increased rates of respiratory complications, myocardial infarction, stroke, and heart failure. kidney and re-surgery. If the signs are detected early and diagnosed in time, the treatment will give better results.
 Objectives: Description of clinical, subclinical characteristics and evaluation of early results of treatment of patients with low cardiac output syndrome after cardiac surgery at Cardiovascular Center, E hospital.
 Methods: Retrospective re
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16

Desai, Akshay S., and John A. Jarcho. "Levosimendan for the Low Cardiac Output Syndrome after Cardiac Surgery." New England Journal of Medicine 376, no. 21 (2017): 2076–78. http://dx.doi.org/10.1056/nejme1705455.

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17

Cavigelli-Brunner, Anna, Maja I. Hug, Hitendu Dave, et al. "Prevention of Low Cardiac Output Syndrome After Pediatric Cardiac Surgery." Pediatric Critical Care Medicine 19, no. 7 (2018): 619–25. http://dx.doi.org/10.1097/pcc.0000000000001533.

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18

L. Epting, Conrad, Mary E. McBride, Eric L. Wald, and John M. Costello. "Pathophysiology of Post-Operative Low Cardiac Output Syndrome." Current Vascular Pharmacology 14, no. 1 (2015): 14–23. http://dx.doi.org/10.2174/1570161113666151014123718.

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19

Drennan, Sarah E., Kathryn Y. Burge, Edgardo G. Szyld, et al. "Clinical and Laboratory Predictors for the Development of Low Cardiac Output Syndrome in Infants Undergoing Cardiopulmonary Bypass: A Pilot Study." Journal of Clinical Medicine 10, no. 4 (2021): 712. http://dx.doi.org/10.3390/jcm10040712.

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Cardiac surgery employing cardiopulmonary bypass exposes infants to a high risk of morbidity and mortality. The objective of this study was to assess the utility of clinical and laboratory variables to predict the development of low cardiac output syndrome, a frequent complication following cardiac surgery in infants. We performed a prospective observational study in the pediatric cardiovascular ICU in an academic children’s hospital. Thirty-one patients with congenital heart disease were included. Serum levels of nucleosomes and a panel of 20 cytokines were measured at six time points in the
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20

WHITE, D. A., R. D. LATIMER, and A. ODURO. "Management of low cardiac output syndrome after cardiac surgery using enoximone." Anaesthesia 45, no. 5 (1990): 386–89. http://dx.doi.org/10.1111/j.1365-2044.1990.tb14783.x.

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21

Deppe, Antje Christin, Thorsten C. W. Wahlers, Carolyn Weber, et al. "Levosimendan Reduces Mortality and Low Cardiac Output Syndrome in Cardiac Surgery." Thoracic and Cardiovascular Surgeon 68, no. 05 (2019): 401–9. http://dx.doi.org/10.1055/s-0039-3400496.

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Abstract Background There has been conflicting evidence concerning the effect of levosimendan on clinical outcomes in patients undergoing cardiac surgery. Therefore, we performed a systematic review and conducted this meta-analysis to provide evidence for/against the administration of levosimendan in cardiac surgery patients. Methods We performed a meta-analysis from literature search in PubMed, EMBASE, and Cochrane Library. Only randomized controlled trials comparing the administration of levosimendan in cardiac surgery patients with a control group (other inotrope, standard therapy/placebo,
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22

Dickerson, Heather A., and Anthony C. Chang. "Steroids and low cardiac output syndrome after cardiac surgery in children*." Pediatric Critical Care Medicine 6, no. 4 (2005): 495–96. http://dx.doi.org/10.1097/01.pcc.0000164640.09454.61.

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23

Huang, Jing-bin, Zhao-ke Wen, Wei-jun Lu, Chang-chao Lu, and Xian-ming Tang. "Preoperative Pericardial Effusion is Associated with Low Cardiac Output Syndrome After Pericardiectomy for Constrictive Pericarditis." Heart Surgery Forum 24, no. 3 (2021): E427—E432. http://dx.doi.org/10.1532/hsf.3813.

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Background: Low cardiac output syndrome is the main cause of death after pericardiectomy. Methods: Patients who underwent pericardiectomy for constrictive pericarditis from January 2009 to October 2020 at our hospital were included in the study. Histopathologic studies of pericardium tissue from every patient were performed. All survivors were followed up. Results: Ninety-two consecutive patients underdoing pericardiectomy were included in the study. The incidence of postoperative low cardiac output syndrome was 10.7% (10/92). There were five operative deaths. Mortality and incidence of LCOS i
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24

Wessel, David L. "Managing low cardiac output syndrome after congenital heart surgery." Critical Care Medicine 29, Supplement (2001): S220—S230. http://dx.doi.org/10.1097/00003246-200110001-00004.

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25

Kaplan, Joel A. "Amrinone: Contemporary management of the low cardiac output syndrome." Journal of Cardiothoracic Anesthesia 3, no. 6 (1989): 1. http://dx.doi.org/10.1016/0888-6296(89)90052-5.

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26

Rosseel, P. M. J., F. W. Santman, H. Bouter, and C. S. Dott. "Postcardiac surgery low cardiac output syndrome: dopexamine or dopamine?" Intensive Care Medicine 23, no. 9 (1997): 962–68. http://dx.doi.org/10.1007/s001340050439.

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27

Chen, Alexander L., Bogdan A. Kindzelski, John P. Robinson, Jeffrey M. Altshuler, Thomas A. Schwann, and Alessandro Vivacqua. "Deciphering Low Cardiac Output Syndrome: Insights and Management in Post-Cardiac Surgery." Heart Surgery Forum 27, no. 10 (2024): E1237—E1244. http://dx.doi.org/10.59958/hsf.7737.

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Low cardiac output syndrome (LCOS) is a dysfunctional state of the heart that often results in decreased cardiac output that is insufficient to meet current metabolic demands. LCOS is typically seen after post-cardiac surgery and is often associated with worsened outcomes and rising hospital costs. As cardiovascular disease becomes more common in an aging population, the prevalence of LCOS will inevitably increase. Understanding the underlying pathophysiology and management is essential to patient outcomes. This is a comprehensive review of the epidemiology, pathophysiology, treatment options,
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28

Kusumajaya, Reby, Najib Advani, Piprim B. Yanuarso, and Zulham Effendy. "Biomarkers in low cardiac output syndrome after open cardiac surgery in children." Paediatrica Indonesiana 61, no. 4 (2021): 223–8. http://dx.doi.org/10.14238/pi61.4.2021.223-8.

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Background Corrective cardiac surgery is the standard management for complex congenital heart disease. Cardiopulmonary bypass surgery and post-surgical intensive care may lead to low cardiac output syndrome (LCOS), as a major complication after open heart surgery. To diagnose early LCOS, lactate level, pCO2 gap, and mixed venous oxygen saturation (SvO2) are parameters reported to have correlations with decreased cardiac output, morbidity, and post-cardiac surgery mortality.
 Objective To determine the usefulness of lactate level, pCO2 gap (arterial-vein), and SvO2 for early detection of L
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29

Marwali, Eva M., Putri Caesa, Sekarpramita Darmaputri, et al. "Oral Triiodothyronine Supplementation Decreases Low Cardiac Output Syndrome After Pediatric Cardiac Surgery." Pediatric Cardiology 40, no. 6 (2019): 1238–46. http://dx.doi.org/10.1007/s00246-019-02143-x.

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30

Luan, Nguyen Thanh. "Study of predictors of low cardiac output syndrome after cardiac valve surgery." Tạp chí Phẫu thuật Tim mạch và Lồng ngực Việt Nam 42 (July 25, 2023): 5–15. http://dx.doi.org/10.47972/vjcts.v42i.896.

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Objective: Low cardiac output syndrome (LCOS) is defined as a decrease in cardiac index (CI) <2.0L/min/m2 and systolic blood pressure <90mmHg, accompanied by signs of a tissue hypoperfusion (cool peripheries, clammy skin, altered mental status, reduced urine output, elevated serum lactate levels) and the need for medication or mechanical circulatory support to improve hemodynamics [4,7]. LCOS is one of the serious complications after open cardiac surgery with a rate of 2-14% depending on the patient and the risk of death increases 12-25 times [3]. Besides modern equipment, early detectio
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31

Nordness, Matthew J., Ashly C. Westrick, Heidi Chen, and Mark A. Clay. "Identification of Low Cardiac Output Syndrome at the Bedside: A Pediatric Cardiac Intensive Care Unit Survey." Critical Care Nurse 39, no. 2 (2019): e1-e7. http://dx.doi.org/10.4037/ccn2019794.

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BACKGROUND Low cardiac output syndrome is a transient constellation of signs and symptoms that indicate the heart’s inability to supply sufficient oxygen to tissues and end-organs to meet metabolic demand. Because the term lacks a standard clinical definition, the bedside diagnosis of this syndrome can be difficult. OBJECTIVE To evaluate concordance among pediatric cardiac intensive care unit nurses in their identification of low cardiac output syndrome in pediatric patients after cardiac surgery. METHODS An anonymous survey was distributed to 69 pediatric cardiac intensive care unit nurses. T
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32

Rogers, Libby, Samiran Ray, Mae Johnson, et al. "The Inadequate Oxygen Delivery Index and Low Cardiac Output Syndrome Score As Predictors of Adverse Events Associated With Low Cardiac Output Syndrome Early After Cardiac Bypass*." Pediatric Critical Care Medicine 20, no. 8 (2019): 737–43. http://dx.doi.org/10.1097/pcc.0000000000001960.

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33

SATO, NAOSHI, NAOKI UCHIDA, MAKOTO MIURA, et al. "Risk Analysis of Low Cardiac Output Syndrome after Valve Replacement." Tohoku Journal of Experimental Medicine 171, no. 1 (1993): 77–88. http://dx.doi.org/10.1620/tjem.171.77.

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34

Günnicker, M., and W. Hess. "Preliminary Results with Amrinone in Perioperative Low Cardiac Output Syndrome." Thoracic and Cardiovascular Surgeon 35, no. 04 (1987): 219–25. http://dx.doi.org/10.1055/s-2007-1020234.

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35

Fang, Likui, Pengfei Zhu, Guocan Yu, Wang Lv, and Jian Hu. "Effect of Levosimendan on Low Cardiac Output Syndrome After Pericardiectomy." Therapeutics and Clinical Risk Management Volume 20 (December 2024): 861–69. https://doi.org/10.2147/tcrm.s496574.

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36

Rao, Vivek, Joan Ivanov, Richard D. Weisel, John S. Ikonomidis, George T. Christakis, and Tirone E. David. "Predictors of low cardiac output syndrome after coronary artery bypass." Journal of Thoracic and Cardiovascular Surgery 112, no. 1 (1996): 38–51. http://dx.doi.org/10.1016/s0022-5223(96)70176-9.

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37

Dosios, T., and D. Angouras. "Low cardiac output syndrome complicating subxiphoid pericardiostomy for pericardial effusion." Journal of Thoracic and Cardiovascular Surgery 113, no. 1 (1997): 220. http://dx.doi.org/10.1016/s0022-5223(97)70423-9.

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38

Álvarez, Julián. "Levosimendan and Low Cardiac Output Syndrome. Does Mortality Really Decrease?" Revista Española de Cardiología (English Edition) 61, no. 5 (2008): 454–57. http://dx.doi.org/10.1016/s1885-5857(08)60162-0.

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39

Belkho, W., J. SAFI, L. Rachid, et al. "Cardiac Tamponade in Eisenmenger Syndrome: A Diagnosing Complexity: Case Report." SAS Journal of Medicine 8, no. 3 (2022): 131–33. http://dx.doi.org/10.36347/sasjm.2022.v08i03.003.

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Cardiac tamponade is a form of obstructive shock with clinical manifestations consistent with a low cardiac output and high central venous pressure. Features of a low cardiac output include low mean arterial pressure, cold peripheries and signs of poor end-organ perfusion. Characteristically, palpating the pulse reveals an apparent variation in pulse volume because of pulsus paradoxus. Jugular venous pressure is typically increased, with distended neck veins apparent. Sympathetic tone is increased in an attempt to compensate for the low cardiac output and manifests as tachycardia, diaphoresis,
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40

Abdelbaki, M., Y. Sayad, and A. Boureghda. "Levosimendan In Cardiology and Cardiac Surgery." Clinical Medicine And Health Research Journal 3, no. 5 (2023): 601–3. http://dx.doi.org/10.18535/cmhrj.v3i5.259.

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Introduction: levosimendan is an inodilator successfully used in the treatment of acute and chronic heart failure. Its use in the treatment of low cardiac output syndrome pre- and postoperatively after cardiac surgery under extracardiac circulation is poorly documented, but it appears to be a very interesting alternative in terms of morbimortality. Aim of the study: to evaluate the value of levosimendan versus dobutamine in the rapid weaning of inotropic drugs in low output patients awaiting cardiac surgery and after surgery under extracorporeal circulation. Materials and methods: sixty patien
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41

Bautista-Hernandez, Victor, Georgios Karamanlidis, James D. McCully, and Pedro J. del Nido. "Cellular and Molecular Mechanisms of Low Cardiac Output Syndrome after Pediatric Cardiac Surgery." Current Vascular Pharmacology 14, no. 1 (2015): 5–13. http://dx.doi.org/10.2174/1570161113666151014122557.

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42

Ferrer-Barba, Angela, Iria Gonzalez-Rivera, and Victor Bautista-Hernandez. "Inodilators in the Management of Low Cardiac Output Syndrome After Pediatric Cardiac Surgery." Current Vascular Pharmacology 14, no. 1 (2015): 48–57. http://dx.doi.org/10.2174/1570161113666151014125314.

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43

Khubulava, G. G., A. B. Naumov, S. P. Marchenko, et al. "Blood gas analysis in newborns with low cardiac output syndrome after cardiac surgery." Bulletin of Bakoulev Center "Cardiovascular Diseases" 19, no. 5 (2018): 676–87. http://dx.doi.org/10.24022/1810-0694-2018-19-5-676-687.

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44

Luber, John, Andra Duncan, Paula Bokesch, Bobbie James, Doug Randall, and John Kelley. "27: RESOURCE UTILIZATION AND COST OF LOW CARDIAC OUTPUT SYNDROME AFTER CARDIAC SURGERY." Critical Care Medicine 44, no. 12 (2016): 93. http://dx.doi.org/10.1097/01.ccm.0000508745.06395.42.

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45

Madhavarapu, Swetha, Lisa Rosen, David Meyer, Vincent Parnell, James Schneider, and Adnan Bakar. "231: INTRAOPERATIVE REGIONAL SATURATION TO PREDICT LOW CARDIAC OUTPUT SYNDROME AFTER CARDIAC SURGERY." Critical Care Medicine 44, no. 12 (2016): 135. http://dx.doi.org/10.1097/01.ccm.0000508911.13472.bb.

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46

Christenson, J. T., J. M. Aeberhard, P. Badel, et al. "Adult Respiratory Distress Syndrome after Cardiac Surgery." Cardiovascular Surgery 4, no. 1 (1996): 15–21. http://dx.doi.org/10.1177/096721099600400104.

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Adult respiratory distress syndrome, characterized by high permeability pulmonary oedema caused by endothelial cell damage, resulting in refractory hypoxemia, has a very high mortality. Cardiopulmonary bypass is said to be responsible for the development of adult respiratory distress syndrome after cardiac surgery. The present study was performed in order to identify predicting and aetiological factors of adult respiratory distress syndrome and multiple organ failure after cardiac surgery. Between January 1984 and December 1993, 3848 patients underwent cardiac surgery with cardiopulmonary bypa
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47

Dosios, Theodosios, Alexander Stefanidis, Christos Chatziantoniou, and Sophia Sgouropoulou. "Thorough Clinical Investigation of Low Cardiac Output Syndrome After Subxiphoid Pericardiostomy." Angiology 58, no. 4 (2007): 483–86. http://dx.doi.org/10.1177/0003319706291147.

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48

KUMON, KEIJI, KAZUHIKO TANAKA, NOBUYUKI NAKAJIMA, YASUAKI NAITO, and TSUYOSHI FUJITA. "Pulmonary circulation in low cardiac output syndrome following open heart surgery." Japanese Circulation Journal 49, no. 10 (1985): 1055–62. http://dx.doi.org/10.1253/jcj.49.1055.

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49

Kunt, Alper Sami, and Mehmet Halit Andac. "Decrease of Total Antioxidative Capacity in Developed Low Cardiac Output Syndrome." Oxidative Medicine and Cellular Longevity 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/356301.

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Background. It has been known that cardiac surgery induces an oxidative stress. The persistent oxidative stress during reperfusion may lead to depressed myocardial function resulting in low cardiac output syndrome (LCOS) necessitating inotropic or intra-aortic balloon counterpulsation support. Total antioxidant capacity (TAC) is a measurement of oxidative stress in tissues. The purpose of this study was to examine the TAC differences during coronary artery bypass graft (CABG) operation in patients who have developed LCOS and who have not.Material and Methods. Seventy-nine patients were enrolle
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50

Maganti, Manjula, Mitesh Badiwala, Amir Sheikh, et al. "Predictors of low cardiac output syndrome after isolated mitral valve surgery." Journal of Thoracic and Cardiovascular Surgery 140, no. 4 (2010): 790–96. http://dx.doi.org/10.1016/j.jtcvs.2009.11.022.

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