Relevant bibliographies by topics / Low-density microarray

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Low-density microarray'

Author: Grafiati
Published: 21 February 2023
Last updated: 31 July 2025

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Journal articles on the topic "Low-density microarray"

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Lacroix, M., N. Zammatteo, J. Remacle, and G. Leclercq. "A Low-Density DNA Microarray for Analysis of Markers in Breast Cancer." International Journal of Biological Markers 17, no. 1 (2002): 5–23. http://dx.doi.org/10.1177/172460080201700102.

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Breast cancer remains a major cause of death in women from Western countries. In the near future, advances in both nucleic acids technology and tumor biology should be widely exploited to improve the diagnosis, prognosis, and outcome prediction of this disease. The DNA microarray, also called biochip, is a promising tool for performing massive, simultaneous, fast, and standardized analyses of multiple molecular markers in tumor samples. However, most currently available microarrays are expensive, which is mainly due to the amount (several thousands) of different DNA capture sequences that they
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Kim, MinGin, Jongwon Kim, Sun-Hee Kim, and Jong-Dae Kim. "Fast Spot Locating for Low-Density DNA Microarray." Sensors 25, no. 7 (2025): 2135. https://doi.org/10.3390/s25072135.

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Low-density DNA microarrays are crucial in molecular diagnostics due to their cost-effectiveness and high sensitivity. However, reliable spot localization remains challenging due to positional variations and image artifacts. Traditional intensity-based methods often struggle with weak fluorescence signals. To address this, we propose a rapid spot localization method that combines template matching with point pattern matching, enhanced through vectorized programming and square (box) templates. Vectorized programming accelerated the most time-consuming calculation by 82 times on a PC and was 600
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Álvarez, Patricia, Pilar Sáenz, David Arteta, et al. "Transcriptional Profiling of Hematologic Malignancies with a Low-Density DNA Microarray." Clinical Chemistry 53, no. 2 (2007): 259–67. http://dx.doi.org/10.1373/clinchem.2006.075887.

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Abstract Background: High-density microarrays are powerful tools for expression analysis of thousands of genes simultaneously; however, experience with low-density microarrays in gene expression studies has been limited. Methods: We developed an optimized procedure for gene expression analysis based on a microarray containing 538 oligonucleotides and used this procedure to analyze neoplastic cell lines and whole-blood samples from healthy individuals and patients with different hematologic neoplasias. Hierarchical clustering and the Welch t-test with adjusted P values were used for data analys
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Gillet, Jean-Pierre, Thomas Efferth, Damiel Steinbach, et al. "ABCChips as New Diagnostic Tool to Monitoring Multidrug Resistance in Human Tumor Cells to Chemotherapeutics Agents by Expression Profiling of ATP-Binding Cassette Transporter Genes." Blood 104, no. 11 (2004): 4360. http://dx.doi.org/10.1182/blood.v104.11.4360.4360.

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Abstract A major problem in the treatment of tumors represents the development of resistance to chemotherapy. Many mechanisms are responsible for the failure of treatment, the main one being the activation of the ABC transporters. In the present investigation, we developed a low density DNA microarray which contains 38 ABC transporter genes. This tool has been validated with three different characterized multidrug-resistant sublines (CEM/ADR5000, HL60/AR, MCF7-CH1000) and their corresponding drug-sensitive parental cell lines (CCRF-CEM, HL60, MCF7). The multidrug-resistant cell lines used are
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Ki, Jang-Seu, Dae-Sik Hwang, and Jae-Seong Lee. "Simultaneous detection ofAureliaandChrysaorascyphozoan jellyfish on a DNA microarray." Journal of the Marine Biological Association of the United Kingdom 90, no. 6 (2009): 1111–17. http://dx.doi.org/10.1017/s0025315409990373.

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To demonstrate the effectiveness of microarrays for the detection of jellyfish, we developed a low density DNA chip based on the mitochondrial COI gene sequences of scyphozoans (jellyfish). We designed species-specific oligonucleotide probes by sequence comparisons between scyphozoans and other cnidarians such as hydrozoans and anthozoans. Each amine-labelled capture probe was arrayed onto a silylated slide. PCR products of the COI gene were hybridized to the DNA microarray that contained COI consensus sequences. We tested the ability of the DNA chip to discriminate between species from the ge
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Goji, Noriko, Trevor MacMillan, and Kingsley Kwaku Amoako. "A New Generation Microarray for the Simultaneous Detection and Identification ofYersinia pestisandBacillus anthracisin Food." Journal of Pathogens 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/627036.

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The use of microarrays as a multiple analytic system has generated increased interest and provided a powerful analytical tool for the simultaneous detection of pathogens in a single experiment. A wide array of applications for this technology has been reported. A low density oligonucleotide microarray was generated from the genetic sequences ofY. pestisandB. anthracisand used to fabricate a microarray chip. The new generation chip, consisting of 2,240 spots in 4 quadrants with the capability of stripping/rehybridization, was designated as “Y-PESTIS/B-ANTHRACIS 4x2K Array.” The chip was tested
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Sun, Zhaohui, Wenli Ma, Min Wei, Shuyan Wang, and Wenling Zheng. "Identification of HCV-1b by Low-Density cDNA Microarray-Based Assay." Current Microbiology 55, no. 3 (2007): 211–16. http://dx.doi.org/10.1007/s00284-007-0051-z.

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Shaskolskiy, Boris, Ilya Kandinov, Dmitry Kravtsov, et al. "Hydrogel Droplet Microarray for Genotyping Antimicrobial Resistance Determinants in Neisseria gonorrhoeae Isolates." Polymers 13, no. 22 (2021): 3889. http://dx.doi.org/10.3390/polym13223889.

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A multiplex assay based on a low-density hydrogel microarray was developed to identify genomic substitutions in N. gonorrhoeae that determine resistance to the currently recommended treatment agents ceftriaxone and azithromycin and the previously used drugs penicillin, tetracycline, and ciprofloxacin. The microarray identifies 74 drug resistance determinants in the N. gonorrhoeae penA, ponA, porB, gyrA, parC, rpsJ, mtrR, blaTEM, tetM, and 23S rRNA genes. The hydrogel elements were formed by automated dispensing of nanoliter-volume droplets followed by UV-induced copolymerization of NH2-contain
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AJIKUMAR, PARAYIL KUMARAN, JIN KIAT NG, JIM YANG LEE, GREGORY STEPHANOPOULOS, and HENG-PHON TOO. "NANOSTRUCTURED DENDRIMER MODIFIED GLASS SURFACES FOR PROTEIN MICROARRAY." International Journal of Nanoscience 06, no. 02 (2007): 161–65. http://dx.doi.org/10.1142/s0219581x07004432.

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Carboxyl PAMAM dendrimer (3.5 generation) was covalently coupled onto amine modified glass surface to prepare a monolayer of high density functional linkers. Activation of the carboxyl PAMAM surface and the subsequent immobilization of antibodies resulted in a high density protein microarray as compared to linear carboxyl linker surface. In addition, fluorescent labeled cell lysate showed extremely low nonspecific adsorption to the PAMAM modified surface, comparable to inert PEG surface. Thus, the carboxyl PAMAM modified surface is ideal for the generation of high density protein arrays for th
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Lacroix, M., N. Zammatteo, J. Remacle, and G. Leclercq. "A low-density DNA microarray for analysis of markers in breast cancer." International Journal of Biological Markers 17, no. 1 (2002): 5–23. http://dx.doi.org/10.5301/jbm.2008.12.

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Dissertations / Theses on the topic "Low-density microarray"

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D'AMICO, FRANCA. "Studio dell'espressione dei geni del metabolismo degli androgeni e caratterizzazione del profilo citogenetico per la ricerca di biomarcatori genomici in linee primarie di carcinoma della prostata." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2008. http://hdl.handle.net/2108/680.

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Obiettivi principali di questa tesi di dottorato sono lo studio dell’espressione genica e del profilo citogenetico, basato sulla tecnologia dei microarrays, per l’identificazione di potenziali biomarcatori genomici quali geni candidati per la comprensione della patogenesi molecolare del tumore della prostata, in linee primarie ottenute da campioni di carcinoma prostatico dopo rimozione chirurgica e lo studio degli eventuali geni differenzialmente espressi nelle colture primarie in linfociti estratti da sangue periferico di pazienti affetti da carcinoma prostatico e non trattati farmacologicame
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Konstantinidou, Valentini. "Molecular mechanisms involved in the protective effect of Mediterranean diet and olive oil consumption in humans." Doctoral thesis, Universitat Pompeu Fabra, 2010. http://hdl.handle.net/10803/7208.

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The scope of the present work was to investigate whether the protective role of the traditional Mediterranean diet (TMD), and virgin olive oil (VOO) rich in phenolic compounds (PC), towards cardiovascular disease can be mediated through gene expression changes. Two trials were performed to assess the in vivo nutrigenomic effects of TMD and VOO in healthy volunteers. The results point out: a) significant gene expression changes of those genes related with cardiovascular-risk processes after VOO ingestion; b) a down-regulation in the expression of atherosclerosis-related genes after a 3-month in
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Lu, Yen-Jung, and 陸燕榮. "Global Screening of Methylated Genes in Gastric Cancer by Differential Methylation Hybridization and CpG DNA Microarray and Identification of Low Density Lipoprotein Receptor-Related Protein 1B as a Potential Tumor Suppressor Gene in Gastric Cancer." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/93497197014267446088.

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博士<br>國立陽明大學<br>微生物及免疫學研究所<br>98<br>Gastric cancer is the second most common cancer worldwide, while in Taiwan it is the fifth leading cause of cancer-related death. Several factors have been implicated in the development of gastric cancer, including chromosomal instability, genetic and epigenetic alterations, Helicobacter pylori infection, and environmental factors such as diet and smoking. Among them, the aberrant methylation of CpG dinucleotides has been reported during tumorigenesis in gastric cancer. In this study, we used CpG island microarray and differential methylation hybridization (
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Book chapters on the topic "Low-density microarray"

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Matson, Robert S., Raymond C. Milton, Michael C. Cress, Tom S. Chan, and Jang B. Rampal. "Printing Low Density Protein Arrays in Microplates." In Microarrays. Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-303-5_17.

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Patel, Ms Nidhi N., Ms Janki Thakkar, Janki B. Patel, Trupal Bhalala, Krutikkumar Shah, and Zuva Laetitiva. "FUTURE TRENDS IN DNA MICROARRAY TECHNOLOGY." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 14. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bkpn14p1ch7.

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This article examines recent advancements in DNA microarray technology as well as applications for it. We go into great detail on the various DNA microarray or DNA chip technologies, their manufacturing procedures, and applications. This covers both low-density microarrays for various diagnostic uses and high-density microarrays for high-throughput screening applications. The described microarray fabrication methods include various inkjet and microjet deposition or spotting techniques, electronic DNA probe addressing mechanisms, and in situ or on-chip photolithographic oligonucleotide synthesi
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Conference papers on the topic "Low-density microarray"

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Gruhler, Holger, Nicolaus Hey, Martin Müller, et al. "Topspot: A New Method for the Fabrication of Biochips." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0299.

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Abstract We present a new method for generating microarrays of liquid droplets. This is of basic importance for the fabrication of so called biochips. To generate a microarray we use a print-module containing 24 nozzles. Each nozzle is connected to one of 24 different reservoirs on the same print-module. By applying a high acceleration to the print-module it can be achieved that all of the 24 nozzles eject a small droplet at the same time. This effect is due to the inertia of the liquid inside the print-module. This new method makes the production of low and medium density biochips much faster
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Mallen, Maria, Diana Bonilla, Maria Diaz-Gonzalez, et al. "Conductimetric transducer array for the readout of low-density protein microarrays." In 2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII). IEEE, 2013. http://dx.doi.org/10.1109/transducers.2013.6626992.

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Duan, Liang, Yonghui Song, Siqing Xia, et al. "Detection of microbial communities in continuous and discontinuous membrane bioreactor using high-density oligonucleotide Microarray." In 2nd International Symposium on Aqua Science, Water Resource and Low Carbon Energy. AIP, 2010. http://dx.doi.org/10.1063/1.3529266.

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Rocha, Aline Carvalho, and Victor Piana Andrade. "The role of tumor-associated macrophages in the prediction of sentinel lymph node involvement in breast cancer." In Brazilian Breast Cancer Symposium 2024. Mastology, 2024. http://dx.doi.org/10.29289/259453942024v34s1031.

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Objective: The purpose of this study was to evaluate the association between the TAM density of breast tumor stroma and sentinel lymph node involvement. Methodology: The cohort consisted of patients with histopathological diagnosis of early-stage invasive breast cancer submitted to mastectomy or quadrantectomy and sentinel lymph node biopsy between January 2007 and December 2012 at a Brazilian referral hospital (A.C.Camargo Cancer Center). Using tissue microarrays, 101 tumors were submitted to immunohistochemistry for total macrophages (CD68), M2 macrophages (CD163), M1 macrophages (HLA-DR), a
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