Academic literature on the topic 'Low-grade obesity'

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Journal articles on the topic "Low-grade obesity"

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Pereira, Solange S., and Jacqueline I. Alvarez-Leite. "Low-Grade Inflammation, Obesity, and Diabetes." Current Obesity Reports 3, no. 4 (2014): 422–31. http://dx.doi.org/10.1007/s13679-014-0124-9.

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Wärnberg, Julia, Karen Cunningham, Javier Romeo, and Ascension Marcos. "Physical activity, exercise and low-grade systemic inflammation." Proceedings of the Nutrition Society 69, no. 3 (2010): 400–406. http://dx.doi.org/10.1017/s0029665110001928.

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Prospective studies have shown that chronic low-grade inflammation may contribute to the pathogenesis of the most common chronic diseases and in particular CVD. Obesity has repeatedly been associated with moderately raised levels of inflammation, and this observation has led to the view that obesity is characterised by a state of chronic low-grade inflammation. There is now great interest in elucidating how physical activity and exercise modulate inflammation. This review summarises the current research addressing the influence of physical activity and exercise in mitigating the risks of obesi
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Devasani, Karan, and Anuradha Majumdar. "Pyrroloquinoline quinone attenuates obesity associated low grade inflammation." Obesity Medicine 16 (December 2019): 100134. http://dx.doi.org/10.1016/j.obmed.2019.100134.

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Tam, C. S., K. Clément, L. A. Baur, and J. Tordjman. "Obesity and low-grade inflammation: a paediatric perspective." Obesity Reviews 11, no. 2 (2010): 118–26. http://dx.doi.org/10.1111/j.1467-789x.2009.00674.x.

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Herder, Christian, Sophie Schneitler, Wolfgang Rathmann, et al. "Low-Grade Inflammation, Obesity, and Insulin Resistance in Adolescents." Journal of Clinical Endocrinology & Metabolism 92, no. 12 (2007): 4569–74. http://dx.doi.org/10.1210/jc.2007-0955.

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Abstract Context: Low-grade inflammation is associated with insulin resistance and precedes the onset of type 2 diabetes mellitus in adults, but there are no comparable data in youth. Objective: The objective of the study was to characterize the pattern of subclinical immune activation that is associated with indices of obesity and insulin resistance in youth and analyze whether this association is explained by obesity. Design: This was a cross-sectional study. Setting: Medical check-up of schoolchildren was conducted by the Public Health Office in Düsseldorf (Germany). Participants: Particip
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Power Guerra, Nicole, Luisa Müller, Kristin Pilz, et al. "Dietary-Induced Low-Grade Inflammation in the Liver." Biomedicines 8, no. 12 (2020): 587. http://dx.doi.org/10.3390/biomedicines8120587.

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The literature describes a close correlation between metabolic disorders and abnormal immune responses, like low-grade inflammation (LGI), which may be one mechanistic link between obesity and various comorbidities, including non-alcoholic fatty liver disease (NAFLD). In our study, we investigated the influence of dietary composition on obesity-derived LGI in the liver. We used a dietary induced obesity mouse model of C57BL/6J mice fed with high fat diet (HFD, 60% fat, 20% protein, 20% carbohydrates) and two different controls. One was rich in carbohydrates (10% fat, 20% protein, 70% carbohydr
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Chen, Chang, Zhijuan Jin, You Yang, et al. "Association of low birth weight with thinness and severe obesity in children aged 3–12 years: a large-scale population-based cross-sectional study in Shanghai, China." BMJ Open 9, no. 5 (2019): e028738. http://dx.doi.org/10.1136/bmjopen-2018-028738.

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ObjectivesLow birth weight (BW) is a general symbol of inadequate intrauterine conditions that elicit abnormal fetal growth and development. The aim of current study is to investigate the relationship between low BW and thinness or severe obesity during maturation.DesignA large-scale cross-sectional population-based survey.Setting134 kindergartens and 70 elementary schools.Participants70 284 Chinese children aged 3–12 years.Outcome measuresInternational Obesity Task Force body mass index (BMI) cut-offs were used to define grade 1, grade 2 and grade 3 thinness, overweight, obesity and severe ob
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Arif Ali, Muhammad, and Faran Nasir. "OBESITY." Professional Medical Journal 23, no. 02 (2016): 198–203. http://dx.doi.org/10.29309/tpmj/2016.23.02.1068.

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Objectives: To find out the prevalence of risk factors of heart diseases in obesepatients. Study Design: Descriptive cross-sectional study. Setting: OPD of IndependentUniversity Hospital, Faisalabad. Period: One week duration extending from 4th to 10th May 2015.Patients and Methods: 90 Patients were selected by convenient sampling. A semi-structuredquestionnaire was used to collect the information from the sample. An informed consent wasalso obtained from the respondents under study and the secrecy of information was ensured.Results: Of the 90 patients under study, 33 (36.26%) were Grade 1 Obe
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Chen, Chang, Zhijuan Jin, You Yang, et al. "Prevalence of grade 1, 2 and 3 thinness is associated with lower socio-economic status in children in Shanghai, China." Public Health Nutrition 19, no. 11 (2016): 2002–10. http://dx.doi.org/10.1017/s1368980016000045.

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AbstractObjectiveWe aimed to investigate the prevalence of grade 1, 2 and 3 thinness among Chinese children and to explore their associations with socio-economic status (SES).DesignA population, school-based cross-sectional study using multistage, stratified cluster random sampling. Grade 1, 2 and 3 thinness, overweight, obesity and severe obesity were defined by the International Obesity Task Force BMI cut-offs.SettingSeven districts of Shanghai, China.SubjectsChinese children aged 3–12 years (n 84 075).ResultsIn boys and girls, respectively, the prevalence of grade 1 thinness was 8·89 % and
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Yang, Jiaxin, Wanyi Li, and Yuanwei Wang. "Capsaicin Reduces Obesity by Reducing Chronic Low-Grade Inflammation." International Journal of Molecular Sciences 25, no. 16 (2024): 8979. http://dx.doi.org/10.3390/ijms25168979.

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Chronic low-grade inflammation (CLGI) is associated with obesity and is one of its pathogenetic mechanisms. Lipopolysaccharide (LPS), a component of Gram-negative bacterial cell walls, is the principal cause of CLGI. Studies have found that capsaicin significantly reduces the relative abundance of LPS-producing bacteria. In the present study, TRPV1-knockout (TRPV1−/−) C57BL/6J mice and the intestinal epithelial cell line Caco-2 (TRPV1−/−) were used as models to determine the effect of capsaicin on CLGI and elucidate the mechanism by which it mediates weight loss in vivo and in vitro. We found
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Dissertations / Theses on the topic "Low-grade obesity"

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Leggate, Melanie. "The IL-6 system and its interaction with chronic low-grade inflammation and high intensity intermittent exercise." Thesis, Loughborough University, 2012. https://dspace.lboro.ac.uk/2134/10184.

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The IL-6 system is key in the development of chronic low-grade inflammation. It is known to be upregulated in response to acute exercise and lowered at rest after exercise training. IL-6 has both anti- and pro-inflammatory properties and moderation of this cytokine could alleviate chronic low-grade inflammation which is associated with obesity and Type 2 diabetes mellitus (T2DM). This thesis investigated the interplay between inflammation, glycaemic control and high intensity intermittent training (HIIT) - an exercise regimen that has been shown to yield many health benefits. There was a great
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Pretorius, Rachelle Ann. "Body composition and systematic low-grade inflammation in children : the PLAY study / Rachelle A. Pretorius." Thesis, North-West University, 2006. http://hdl.handle.net/10394/1096.

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Background: Obesity-related diseases are arising as a major problem among children. inflammation has recently been identified to play an important role in the relationship between obesity.- as well as stunting-related diseases. Objectives: The aim of this study was to assess the association between serum tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and C-reactive protein (CRP) concentrations and a variety of cardiometabolic and anthropometric indices of children in a township outside Potchefstroom, South Africa. Methods: Blood samples of 115 girls and 78 boys (mean age 15.6 ± 1.3
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Lasselin, Julie. "L’inflammation chronique à bas bruit et ses relations avec la fatigue et les altérations cognitives chez les patients souffrant de troubles métaboliques." Thesis, Bordeaux 2, 2012. http://www.theses.fr/2012BOR22001/document.

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Les cytokines, produites lors de l’activation du système immunitaire, ont la capacité d’agir au niveau du système nerveux central et d’induire diverses altérations comportementales. Lorsque l’activation du système de l’immunité innée devient chronique, ces altérations comportementales peuvent évoluer en véritables symptômes neuropsychiatriques. La physiopathologie des symptômes neuropsychiatriques qui se développent dans un contexte d’inflammation chronique à bas bruit, c’est-à-dire caractérisé par une activation chronique des processus immunitaires mais à un niveau relativement faible, est pe
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Blomquist, Caroline. "Metabolic consequences of a Paleolithic diet in obese postmenopausal women." Doctoral thesis, Umeå universitet, Institutionen för folkhälsa och klinisk medicin, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-143133.

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Background Obesity, in particular abdominal adiposity, is associated with elevated fatty acids and pro-inflammatory adipokines, which are linked to ectopic fat storage and insulin resistance. During menopause, there is a redistribution of fat from the peripheral to abdominal depots. This transition is associated with an increased risk of type 2 diabetes and cardiovascular diseases. We hypothesized that a Paleolithic diet, with high proportions of lean meat, fish, vegetables, fruits, and oils, but devoid of dairy products and cereals, might have long-term beneficial effects on inflammation, fat
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Miles-Brown, Jennifer. "Microbiota Metabolism of Soluble Fiber Protects Against Low Grade Inflammation and Metabolic Syndrome." 2016. http://scholarworks.gsu.edu/biology_diss/184.

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Metabolic syndrome (MetS) is a group of obesity-related metabolic abnormalities that predisposes to type II diabetes mellitus (T2DM) and cardiovascular disease. The dramatic increase in incidence of obesity and MetS over the last 25 years amidst relatively constant host genetics supports the role for non-genetic factors such as gut microbiota composition as an important contributor to the development of these disorders. Microbiota can interact with the host, in a manner influenced by genetics and diet that result in low-grade chronic inflammation. A critical risk factor for the pathogenesis o
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Barretto, David Gunabe. "Comparative analysis of hypothalamic damage caused by pediatric craniopharyngioma versus pediatric low grade gliomas." Thesis, 2014. https://hdl.handle.net/2144/14686.

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Numerous studies have suggested rapid weight gain following diagnosis and initial treatment of childhood craniopharyngioma (CP) due to the damage sustained by the hypothalamus. Hypothalamic lesions formed by the treatment of the tumor and/or by invasiveness of the tumor itself are known to cause intractable weight gain, known as hypothalamic obesity. In contrast, hypothalamic obesity manifested in pediatric low-grade glioma (PLGG) patients is not as prominently addressed in literature; likely due to the expansive set of histological tumor subtypes that makes generalization challenging. Specifi
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Li, Yijing. "Using a non-diet approach to prevent overweight and obesity among 6th to 8th grade youth in a low-income racial/ethnic community in Kansas." Diss., 2018. http://hdl.handle.net/2097/38835.

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Doctor of Philosophy<br>Department of Food, Nutrition, Dietetics and Health<br>Tandalayo Kidd<br>Objective: The purpose of this study is to promote healthy dietary and physical activity (PA) behaviors in adolescents using a six-module nutrition education resource—Wise Eating (WE)—which was designed specifically for the adolescent population based on the concept and principles of Intuitive Eating (IE).  Study Design: Repeated measures study with pre-assessment and post-assessment. Outcome Measures and Analysis: This study assessed participating adolescents’ breakfast intake, fruit and veg
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Mráz, Miloš. "Nové metabolické regulátory a prozánětlivé faktory v etiopatogeneze diabetes mellitus 2. typu a obezity: vliv farmakologických a dietních intervencí." Doctoral thesis, 2011. http://www.nusl.cz/ntk/nusl-311567.

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NOVEL METABOLIC REGULATORS AND PROINFLAMMATORY FACTORS IN THE ETIOPATHOGENESIS OF TYPE 2 DIABETES MELLITUS AND OBESITY: THE INFLUENCE OF PHARMACOLOGICAL AND DIETARY INTERVENTIONS MUDr. Miloš Mráz Doctoral Thesis ABSTRACT (EN) Identifying novel factors involved in the etiopathogenesis of obesity, diabetes mellitus and their complications has become one of the primary scopes of metabolic research in the last years. The aim of the present study was to evaluate the role of recently discovered metabolic and inflammatory regulators including fibroblast growth factors 19 and 21 and chemotactic cytoki
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Book chapters on the topic "Low-grade obesity"

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Badimon, Lina, Stefan D. Anker, and Stephan von Haehling. "Obesity." In The ESC Textbook of Heart Failure, edited by Petar M. Seferović, Andrew J. S. Coats, Gerasimos Filippatos, Stefan D. Anker, Johann Bauersachs, and Giuseppe Rosano. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/med/9780198891628.003.0016.

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Abstract Obesity is a growing cardiovascular health problem, which is highly prevalent in the general population, as well as in patients with heart failure. Obesity is a risk factor for developing heart failure. Among patients with manifest heart failure, it affects 36–51% and 26–37% of patients with heart failure with preserved and reduced ejection fraction, respectively. The accumulation of adipocytes in obesity fuels a pro-inflammatory response that propagates into a low-grade systemic inflammation, with a large variety of metabolic alterations. In the myocardium, mitochondrial uncoupling i
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Balderas-Peña, Luz-Ma Adriana, Daniel Sat-Muñoz, Mario-Alberto Mireles-Ramírez, et al. "Influence of chronic low-grade inflammation on the systemic inflammatory response." In Multisystem Inflammatory Syndrome - Natural History and Prevention Levels [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.1002764.

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The chronic inflammatory state is a common condition in obesity. It has become a health problem with pandemic proportions that, in some developing countries, jointly to overweight, affects more than 50% of their population. As a part of the scenario, we observe how a significant proportion of people with overweight or obesity have raised the acute inflammatory response markers. This situation shows us how this chronic condition can trigger aggressive inflammatory phenomena in critically ill patients with other clinical conditions, occasioning torpid clinical evolution, ominous results, and low
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Jassil, Friedrich C., and Rachel L. Batterham. "Medical Complications of Obesity." In Oxford Textbook of Endocrinology and Diabetes 3e, edited by John A. H. Wass, Wiebke Arlt, and Robert K. Semple. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198870197.003.0224.

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Obesity is a chronic progressive condition. It is associated with adverse health outcomes affecting the cardiovascular, endocrine, gastrointestinal, urinary, respiratory, nervous, musculoskeletal, and reproductive systems. Obesity also increases the risk of certain malignancies and psychological comorbidities. The aetiopathogenesis of obesity-linked diseases is complex and not yet fully elucidated, however, clinical and experimental observations, as well as epidemiological studies, have identified a key role for adipocyte-derived factors, in particular from visceral adipose tissue and ectopic
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Farias, Gisele, Carolina K. Shiba, Bárbara D. M. Netto, et al. "Effects of interdisciplinary therapy on reducing ultra-processed food consumption and its impact on cardiometabolic risks factor in women with obesity." In DEVELOPMENT AND ITS APPLICATIONS IN SCIENTIFIC KNOWLEDGE. Seven Editora, 2023. http://dx.doi.org/10.56238/devopinterscie-109.

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The prevalence of obesity has grown at an epidemic rate in recent years. According to the World Health Organization (WHO), there are more than 1.9 billion overweight adults, and of these, more than 600 million are classified as being obese, which is equivalent to more than 13% of the world population (1). Obesity is a chronic disease, characterized by the presence of low-grade inflammation, which contributes to the development of other comorbidities including type 2 diabetes mellitus, cardiovascular diseases, non-alcoholic fatty liver disease, and different types of cancer (2).
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Mocanu, Veronica, Daniel V. Timofte, and Ioana Hristov. "Subcutaneous Adipose Stem Cells in Obesity: The Impact of Bariatric Surgery." In Bariatric Surgery - From the Non-surgical Approach to the Post-surgery Individual Care [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95542.

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Adipocyte expansion, which involves adipose tissue-derived mesenchymal stem cells (ASCs), is a critical process with implications in the pathogenesis of metabolic syndrome and insulin resistance associated with obesity. Impaired subcutaneous adipogenesis leads to dysfunctional, hypertrophic adipocytes, chronic low-grade inflammation, and peripheric insulin resistance. Alternatively, it has also been proposed that the preservation of the functionality of subcutaneous adipocyte precursors could contribute to some obese individuals remaining metabolically healthy. Very few studies evaluated the c
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Shmakova, Elena, Irina Larionova, Tatiana Sudarskikh, and Julia Kzhyshkowska. "Perspective Chapter: Monocytes on the Interface of Metabolic Disorders and Colorectal Cancer." In Macrophages - Molecular Pathways and Immunometabolic Processes. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1007011.

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Colorectal cancer (CRC) is a prevalent malignancy with high incidence and mortality rates worldwide. Metabolic disorders, such as obesity, dyslipidemia, hyperglycemia, and hypertension, have been identified as significant risk factors contributing to the development and progression of CRC. These metabolic conditions often result in low-grade inflammation, which plays a crucial role in tumor initiation and progression. Monocytes, which differentiate into tumor-associated macrophages (TAMs) within the tumor microenvironment (TME), are pivotal in mediating these inflammatory responses. Monocytes
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Beyh, Yara S., Riya Sachdeva, K. M. Venkat Narayan, and Manoj Bhasin. "SARS-CoV-2 and Co-morbidities." In COVID-19: Effects in Comorbidities and Special Populations. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815036367122010003.

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In December 2019, cases of pneumonia emerged in Wuhan, China, which was indicated to be due to a novel coronavirus called SARS-CoV-2 or COVID-19. This virus shares a lot of similarities with the previous SARS-Cov and MERS-Cov, yet its spread has been recorded to be much faster, with more than 80 million cases and close to 1 million deaths in the USA by March 2022. Further, the CDC has released a list of health conditions that increase the risk of acquiring the virus and its severity by 12- folds. Those conditions include diabetes, cardiovascular diseases, chronic kidney disease, cancer, chroni
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Conference papers on the topic "Low-grade obesity"

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Alves, Rafael Ribeiro, Victor Domingos Lisita Rosa, Anderson Garcia Silva, et al. "Effects of low volume resistance training on blood pressure changes, glycemic levels, fatigue scores, bone mineral density, and muscle strength: a case study at a university hospital." In Brazilian Breast Cancer Symposium 2024. Mastology, 2024. http://dx.doi.org/10.29289/259453942024v34s1093.

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Objective: This study aimed to evaluate the effects of one resistance training (RT) session per week on indicators of blood pressure, glycemic levels, fatigue scores, bone mineral density, and muscle strength. Methodology: A case study was conducted with an elderly patient (78 years old; body mass: 82.8 kg; height (m): 1.54; body mass index: 34.7 kg/m²), breast cancer survivor, with mastectomy, undergoing hormone therapy, diagnosed with type II diabetes, hypertension, and grade I obesity. The RT consisted of one session per week for 8 weeks. The sessions consisted of only four exercises: bench
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Mulić, Maida, Marijana Srećković, and Selma Salkić. "SCOLIOSIS RISK AMONG SCHOOL-AGE CHILDREN AND THE POSSIBILITY OF THE HEALTH SYSTEM'S RESPONSE." In Global Challenges Through the Prism of Rural Development in the Sector of Agriculture and Tourism GIRR 2024. Academy of Applied Studies Šabac, 2025. https://doi.org/10.46793/girr25.028m.

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Introduction: Scoliosis is a spinal deformity that affects school-age children and adolescents the most. Excessive body weight, heavy school bags, improper sitting at school desks, and reduced physical activity are significant risk factors for the development of scoliosis in children. To prevent the occurrence of scoliosis of the spinal column, the focus of attention must be on early identification and education about scoliosis. The research aims to determine the presence of risk factors for scoliosis in sixth-grade elementary school students, assess knowledge about scoliosis of the spine, and
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Reports on the topic "Low-grade obesity"

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Liu, Yangjun, Wei Xie, Zbigniew Ossowski, et al. Physical activity, abdominal obesity and inflammatory response in the elderly: a systematic review and meta-analysis of randomized-controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.3.0051.

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Review question / Objective: The purpose of this study was to explore the effects of physical activity (i.e., type of exercise, FITT criteria, control group, other interventions) on abdominal obesity and inflammatory response in elderly? The study method was a randomized controlled trial. Condition being studied: An increasing number of studies have demonstrated that chronic inflammation is closely associated with the initiation and progression of a broad range of age-related diseases, such as cardiovascular disease, cancer, diabetes, Alzheimer’s disease, and other neurodegenerative diseases a
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