Relevant bibliographies by topics / Lown, B

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Academic literature on the topic 'Lown, B'

Author: Grafiati
Published: 4 June 2021
Last updated: 27 January 2023

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Journal articles on the topic "Lown, B"

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Nomura, Fumikazu, Seiichiro Ikawa, Keishi Kadoba, Masataka Mitsuno, Yoshiki Sawa, and Hikaru Matsuda. "Prognostic Factors for Late Ventricular Arrhythmias after Repair of Tetralogy of Fallot." Asian Cardiovascular and Thoracic Annals 5, no. 1 (March 1997): 20–24. http://dx.doi.org/10.1177/021849239700500105.

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During a median follow-up period of 9 years (ranging from 9 months to 25 years), 24-hour ambulatory electrocardiographic studies were undertaken in 155 patients after repair of tetralogy of Fallot. The patients were divided into two groups. Group A consisted of 76 patients in whom the right ventricular approach was used and group B comprised 79 patients whose repair was through the right atrium. A transannular patch was employed in all patients in group A and in none of the patients in group B. Age at surgery was between 1 and 37 years (median age 4.8 years). During follow-up, 37 patients (48.6%) in group A had significant ventricular arrhythmias (Lown grade 2 or higher) and 13 patients (15.4%) in group B had significant ventricular arrhythmias. A close relationship was observed between age at surgery and Lown grade (R2 = 0.374, p < 0.001) and between follow-up duration and Lown grade (R2 = 0.514, p < 0.001), especially when the two groups were analyzed separately (R2 = 0.502, 0.476, p < 0.001). In contrast, no significant relationship was observed between the ratio of right ventricular to left ventricular pressure and Lown grade or between right ventricular systolic pressure and Lown grade. Discriminant analysis revealed risk factors associated with postoperative ventricular arrhythmias are follow-up duration (partial F = 3.22, p < 0.01), right ventricular to pulmonary artery pressure gradient (partial F = 3.35, p < 0.01), and operative method (partial F = 2.4, p < 0.05). Despite antiarrhythmic therapy, 11 of 22 late postoperative deaths occurred suddenly, presumably from ventricular arrhythmias. In this series of patients, the right atrial and pulmonary artery approach significantly reduced the risk of life-threatening ventricular arrhythmias after repair of tetralogy of Fallot.
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Ozmen, Caglar, Ali Deniz, Onur S. Deveci, Caglar E. Cagliyan, Aziz I. Celik, İbrahim Yildiz, Pinar Ö. Yildiz, Mesut Demir, and Mehmet Kanadasi. "Association among tenascin-C and NT-proBNP levels and arrhythmia prevalence in heart failure." Clinical & Investigative Medicine 40, no. 6 (December 17, 2017): 219. http://dx.doi.org/10.25011/cim.v40i6.29122.

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Purpose: Tenascin-C (TN-C) and amino-terminal fragment of the B-type natriuretic peptide (NT-proBNP) are the important predictors in prognosis of heart failure (HF). The aim of this study was to analyze the relationship of TN-C and NT-proBNP levels with the frequency and severity of ventricular arrhythmia. Materials and Methods: Our study included 107 HF patients with EF < 45%. According to Holter analysis, the patients were divided into two groups as malignant arrhythmia group (n=29) with Lown Class 4a and 4b arrhythmia and benign arrhythmia group(n=78) with Lown Class 0-3b arrhythmia. The groups were compared with respect to levels of TN-C and NT-proBNP. The relationship of TN-C and NT-proBNP levels with frequency of ventricular premature beat (VPB) was also analyzed. Findings: NT-proBNP (5042.1±1626 versus 1417.1±1711.6 pg/ml) and TN-C (1089±348.6 versus 758.5±423.9 ng/ml) levels were significantly higher in the malignant arrhythmia group than that of the benign arrhythmia group (p
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Shubitidze, Iosif Z., and Vitalii G. Tregubov. "Effects of the b-blockers on the functional state of patients with ventricular arrhythmias." Systemic Hypertension 18, no. 1 (March 15, 2021): 19–24. http://dx.doi.org/10.26442/2075082x.2021.1.200246.

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Sudden cardiac death and the heaviest arrhythmic events are connected to ventricular arrhythmias (VA). The issue of optimization of drug therapy for VA remains relevant. Given the possible multidirectional effects of antiarrhythmic drugs on the functional state, in order to determine the effectiveness of pharmacotherapy in patients with VA it is advisable to use a stepwise integrated approach. Aim. Compare the effects of bisoprolol, nebivolol and sotalol on the functional state of patients with VA. Materials and methods. 120 patients with VA of grade IIV based on the В. Lown grading system, III groups based on J. Bigger grading system against the background of essential hypertension or its combination with coronary heart disease took part in the research, they were randomized into three groups for treatment with bisoprolol, nebivolol and sotalol. As part of combination therapy, patients were administered lisinopril, and if indicated, acetylsalicylic acid, atorvastatin. Initially and after 24 weeks of therapy the following was done: quantitative assessment of regulatory-adaptive status by cardio-respiratory synchronism test, treadmill test, six-minute walk test, subjective assessment of quality of life, all-day monitoring of blood pressure and electrocardiogram. Results. With comparable hypotensive and antiarrhythmic effects, therapy with nebivolol had a positive effect on the regulatory-adaptive status, had a better effect on exercise tolerance in comparison with bisoprolol and sotalol, more improved the quality of life, in comparison with bisoprolol and sotalol. Conclusion. In patients with VA against the background of essential hypertension or its combination with coronary heart disease as part of combination therapy the use of nebivolol may be preferable to bisoprolol or sotalol due to a more pronounced positive effect on the functional state.
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Konovalova, T. V., and N. B. Perepech. "The method for prediction of high-grade premature ventricular contractions in patients with heart failure and preserved ejection fraction." Kardiologiia 60, no. 4 (May 4, 2020): 70–76. http://dx.doi.org/10.18087/cardio.2020.4.n631.

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Aim To develop a method for prediction of high-grade ventricular extrasystole (VE) in patients with chronic heart failure with preserved ejection fraction (CHF-PEF) based on results of an echocardiography (EchoCG) study.Material and methods At the first step, the study included 121 patients of the Cardiology Department, Municipal Clinical Hospital #31, St. Petersburg (calculation group) with symptoms and clinical signs of CHF-PEF (median age, 62 years). For testing accuracy of the developed formula, a control group was formed, which consisted of 42 patients with CHF-PEF (median age, 59 years). EchoCG at rest and ECG Holter monitoring were performed for all patient. The VE classification according to B. Lown and M. Wolf (1971) in the M. Ryan (1975) modification was used. Results of the evaluation were determined by the most significant recorded grade. Grade III or higher VE were considered as high-grade VE.Results Using logistic regression analysis of data for patients of the calculation group, a statistical model was constructed and a respective formula was developed to predict a probability of high-grade VE in CHF-PEF patients depending on the presence of risk factors (EchoCG criteria). According to the obtained data the following factors primarily contributed to the model: interventricular septal (IVS) thickness (p=0.007; Wald=7.44), end-diastolic volume index (EDVI) (p=0.044; Wald=4.13), and the degree of diastolic dysfunction (DD) (p<0.0001; Wald=19.90). For testing the formula accuracy, the analysis was performed in the control group. Based on data of both stages, the following values were obtained: for the calculation group, the method sensitivity was 77.8 %, the specificity was 82.4 %, the accuracy was 81.0 %; for the control group, 81.8 %, 70 %, and 76.2 %, respectively; for both groups together, 79.3 %, 80.0 %, and 79.8 %, respectively. In ROC-analysis of this prognostic model, the area under the ROC-curve (AUC) was 0.852 (95 % CI: 0.776–0.910; p<0.0001) for the calculation group; 0.818 (95 % CI: 0.669–0.920; p<0.0001) for the control group; and 0.855 (95 % CI: 0.792–0.905; p<0.0001) for both groups together, which indicated a good quality of the prognostic model.Conclusion The EchoCG predictors of high-grade VE in patients with CHF-PEF included degree of DD, EDVI, and IVS thickness. The developed method with the constructed formula for prediction of high-grade VE in CHF-PEF patients showed high sensitivity, specificity and accuracy.
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Lim, Sean H., Heng Sheng Sow, Christopher Wignall, Katy Mercer, Josh Caddy, Cherish Boxall, Kerensa Thorne, et al. "Clinical and Biological Effects of Combined CD27 and CD20 Antibody Therapy in Relapsed/Refractory B-Cell Lymphoma: The Riva Trial." Blood 138, Supplement 1 (November 5, 2021): 715. http://dx.doi.org/10.1182/blood-2021-148332.

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Abstract Background: CD27 antibody stimulation of T cells has been shown to activate and promote myeloid cell infiltration leading to enhanced antibody-dependent cellular phagocytosis (ADCP) by anti-CD20 in lymphoma preclinical models (Turaj et al Cancer Cell 2017). In this phase IIa study (RiVa NCT03307746), the safety and efficacy of rituximab (ritux) and varlilumab (varli, anti-CD27) was tested in relapsed/refractory B-cell lymphoma. Transcriptional effects of therapy were investigated by RNA sequencing of pre- and post-treatment tumour biopsies and single cell RNA sequencing of in vitro peripheral blood mononuclear cells (PBMC). Methods: Eligible patients with relapsed/refractory CD20 + B-cell lymphoma were randomized 1:1 to arms A: cycle 1 day 1 ritux, day 2 varli; or B: cycle 1 day 1 ritux, day 8 varli. Cycles 2-6 are identical in both arms (day 1 ritux (cycles 2-6); day 2 varli (cycles 3 and 5); 2-weekly cycles. The primary endpoints were overall response and safety. RiVa was funded by CRUK (CRUKD/17/008) and Celldex Therapeutics Inc. Intratumoral biopsies were taken pre-treatment and on cycle 1 day 7/8 post treatment, i.e. post- ritux and varli in arm A, and post-ritux alone in arm B, and subjected to RNA sequencing, deconvolution by CIBERSORTx and Gene Set Enrichment Analysis (GSEA). To gain further insight into how anti-CD27 stimulated T cells activate myeloid cells, PBMC from healthy donors were treated with varli or an isotype control for 48 h and analysed by CITE-seq (10x Genomics). Results: Twenty-seven patients were randomised; 15 indolent B-cell non-Hodgkin lymphoma cases (NHL) (1 mantle cell lymphoma and 14 follicular lymphoma (FL) grade 1, 2 or 3a) and 12 aggressive B-NHL (9 diffuse large B-cell lymphoma, 2 FL grade 3b and one transformed FL). Median age was 71 (range 49-87), median lines of previous treatment were 4 (range 1-13) and 22% were refractory to the last line of treatment. Thirteen patients completed all 6 cycles of treatment, 1 patient was withdrawn after 1 cycle due to a new cancer diagnosis, 3 patient/investigator withdrawals occurred and 10 progressed on treatment. The overall response rate at the end of treatment was 26.9% (7/26; 95% CI, 13.4-44.7) (indolent B-NHL 26.7% (4/15); aggressive B-NHL 27.3% (3/11)). Within responders, 4 had partial response (PR) (3 aggressive B-NHL, 1 indolent B-NHL) and 3 had stable disease (SD) (all indolent B-NHL), with a duration of response between 2 months to &gt;1 year. Amongst the responders with aggressive B-NHL, one had stage III disease, 3 previous lines of treatment and remained in remission &gt;1 year. Another had stage IV disease, 6 previous lines of treatment including CAR-T cells, and was in remission at last follow up (&gt;16 days). Thirty-three percent (9/27) of patients experienced at least one adverse event graded ≥3 with the commonest being infection (11%, 3 cases). GSEA of post- vs pre-treatment biopsies in ritux/varli-treated (arm A) patients showed pathways enriched in T-cell signalling (normalised enrichment score (NES) 2.47, q-value=0.001) and Fc gamma receptor-dependent phagocytosis (2.05, q=0.001), which were absent in ritux-treated (arm B) patients. CIBERSORTx analysis showed &gt;100-fold increased CD4 T cell infiltration in partial responders compared to those with progressive disease (p=0.027) and a strong correlation between intratumoral B-cell depletion and macrophage infiltration (Fig 1). Responders were enriched in T-cell signalling and Th1 signatures, pre-treatment (NES 2.52, q=0.02). PBMC cultures treated with varli induced CD4 + and CD8 + T-cell effector and memory activation (IFNG, TNFA, NFKB), and monocyte differentiation from classical (CD14 ++CD16 -) into intermediate (CD14 ++CD16 +) and dendritic cell-like (CD14 -CD16 +CD83 +CD86 +) phenotypes. In comparison to isotype control data, receptor-ligand interaction analysis predicted that varli-treated T cells may activate monocytes through the MIF signalling pathway (CD74, CD44, CXCR4). Conclusion: Combined rituximab and varlilumab administration is safe in relapsed/refractory B-cell lymphomas and demonstrates efficacy in patients with T-cell activated tumours. Transcriptomic analysis of pre- and post-treatment samples confirms that varlilumab has in vivo agonistic activity. B-cell depletion by rituximab is dependent on intratumoral macrophages and varlilumab induces myeloid cell activation via a T-cell dependent, MIF signalling pathway. Figure 1 Figure 1. Disclosures Lim: Celldex Therapeutics: Membership on an entity's Board of Directors or advisory committees, Research Funding; Roche: Honoraria. Lown: Roche: Speakers Bureau. McKay: Takeda: Honoraria, Membership on an entity's Board of Directors or advisory committees; Roche: Honoraria, Membership on an entity's Board of Directors or advisory committees; BMS/Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees; Gilead: Honoraria, Membership on an entity's Board of Directors or advisory committees; Beigene: Membership on an entity's Board of Directors or advisory committees; Janssen: Honoraria, Membership on an entity's Board of Directors or advisory committees. Osborne: Pfizer: Honoraria, Other: Travel expenses; Autolus: Membership on an entity's Board of Directors or advisory committees; Syneos: Membership on an entity's Board of Directors or advisory committees; Beigene: Membership on an entity's Board of Directors or advisory committees; Novartis: Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel expenses; Merck Sharp & Dohme: Membership on an entity's Board of Directors or advisory committees; Kite Gilead: Honoraria, Membership on an entity's Board of Directors or advisory committees; Servier: Membership on an entity's Board of Directors or advisory committees; Takeda: Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel expenses; Roche: Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel expenses; AstraZeneca: Honoraria; Kyowa Kirin: Honoraria; Abbvie: Honoraria; Incyte: Honoraria. Linton: BeiGene: Research Funding; University of Manchester: Current Employment; Celgene: Research Funding; Hartley Taylor: Honoraria; Genmab: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Aptitude Health: Honoraria; Roche: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding. Collins: Roche: Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel expenses, Speakers Bureau; Beigene: Membership on an entity's Board of Directors or advisory committees; Novartis: Honoraria, Speakers Bureau; Pfizer: Honoraria; Celgene: Research Funding; Amgen: Research Funding; AstraZeneca: Honoraria, Research Funding; ADC Therapeutics: Honoraria, Membership on an entity's Board of Directors or advisory committees; Celleron: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Merck Sharp & Dohme: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Bristol Myers Squibb: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Gilead: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Takeda: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau. Griffiths: Jannsenn-Cilag: Research Funding; AstraZeneca: Research Funding; Novartis: Research Funding; Astex: Research Funding; Roche: Research Funding; Heartflow: Research Funding; Bristol Myers Squibb: Research Funding; BionTech: Research Funding; Celldex Therapeutics: Other.
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Konttinen, Y. T., D. Nordstrom, and V. Bergroth. "Loin pain and haematuria syndrome:: Authors' reply." BMJ 295, no. 6594 (August 8, 1987): 391–92. http://dx.doi.org/10.1136/bmj.295.6594.391-b.

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Herborn, W. "B. ALEXANDER. ″gab ich an Marie auf Lohn“." Annalen des Historischen Vereins für den Niederrhein 192-193, jg (December 1990): 306–7. http://dx.doi.org/10.7788/annalen-1990-jg89.

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Quintanar, Alejandro, Pilar Catalán, and Santiago Castroviejo. "Adscription ofParafestuca albida(Lowe) E. B. Alexeev toKoeleriaPers." TAXON 55, no. 3 (August 2006): 664–70. http://dx.doi.org/10.2307/25065642.

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Сидь, Е. В., and О. В. Яценко. "The Levels of Markers of Systemic Inflammatory Response among Patients with Acute Myocardial Infarction and Permanent Premature Ventricular Contractions." Кардиология в Беларуси, no. 2 (May 17, 2021): 178–87. http://dx.doi.org/10.34883/pi.2021.13.2.003.

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Введение. Несмотря на значительные достижения современной кардиологии в совершенствовании лечения пациентов c ишемической болезнью сердца, ее клиническая форма – острый инфаркт миокарда – является потенциально фатальным событием и причиной смерти среди взрослого населения. Иммунная система реагирует на острый инфаркт миокарда и развитие его осложнений. Считается, что первопричиной аритмий могут быть иммуновоспалительные реакции. Однако механизмы развития этих реакций при образовании желудочковых аритмий остаются малоизученными. Представляется целесообразным изучить состояние системного воспалительного ответа у пациентов с острым инфарктом миокарда с желудочковыми экстрасистолами. Это позволит оценить роль воспаления в развитии желудочковых аритмий, а также определить прогностическое значение маркеров системного воспалительного ответа у данной группы пациентов.Цель. Проанализировать уровни маркеров системного воспалительного ответа у пациентов с острым инфарктом миокарда со стойкими желудочковыми экстрасистолами.Материалы и методы. В исследовании принял участие 351 пациент с ИБС: 185 человек было с острым инфарктом миокарда со стабильным подъемом сегмента ST и 91 пациент с острым инфарктом миокарда без подъема сегмента ST, контрольную группу составили 75 пациентов со стабильной стенокардией. Выборка пациентов проводилась в период с 2015 г. по февраль 2018 г. В исследовании группа STEMI включала 96 (51,9%) жителей города и 89 (48,1%) жителей из сельской местности, группа NSTEMI состояла из 42 (46,2%) жителей города и 49 (53,8%) жителей из сельской местности. Группы были сопоставимы по доле пациентов из города и из сельской местности. Все обследованные лица были сопоставимы по возрасту, социальному положению и полу (соотношение мужчин и женщин составило 4 к 1).Уровни биомаркеров острого инфаркта миокарда определяли при первом контакте. Для определения биомаркеров воспаления кровь брали через 24 часа после начала клинических проявлений острого инфаркта миокарда.Желудочковые экстрасистолы были выявлены при помощи холтеровского мониторирования ЭКГ в течение 24 часов. Выявление желудочковых экстрасистол проводили через 5 дней послеSTEMI. Критерием включения в исследование было наличие желудочковых экстрасистол 1–2 градаций по B. Lown и турбулентность сердечного ритма.Результаты. Самый высокий уровень высокочувствительного С-реактивного белка был в группе пациентов STEMI и составил 10,63 [9,20–13,44] мг/л и достоверно превышал уровень этого показателя в группе пациентов NSTEMI – 8,47 [7,05–10,61] мг/л (р<0,05). По сравнению с группой пациентов со стабильной ИБС, где уровень высокочувствительного С-реактивного белка составлял 4,78 [3,60–6,45] мг/л, в группе пациентов STEMI его уровень был в 2,3 раза выше (р<0,05). Уровень высокочувствительного С-реактивного белка у пациентов STEMI с желудочковой экстрасистолией составил 11,82 [9,86; 14,00] мг/л и был достоверно выше – 9,67 [7,43; 12,00] мг/л – в подгруппе STEMI без желудочковой экстрасистолией (р<0,05). Наибольшую площадь под кривой ROC (AUC=0,695, 95% ДИ 0,624–0,761) среди анализируемых маркеров иммуновоспалительного ответа имел высокочувствительный С-реактивный белок. В точке отсечения >10,05 мг/л чувствительность составила 70,25%, а специфичность – 64,06%. Относительный риск возникновения желудочковой экстрасистолии у пациентов со STEMI при уровне высокочувствительного С-реактивного белка >10,05 мг/л составил 1,646, 95% ДИ 1,273–2,129.Выводы. Системная воспалительная реакция, лежащая в основе значений уровней высокочувствительного С-реактивного белка, фактора некроза опухоли-α и интерлейкина-6, более выражена у пациентов со STEMI, чем у пациентов с NSTEMI. Относительный риск возникновения желудочковой экстрасистолии увеличивается в 1,646 раза среди пациентов с острым инфарктом миокарда при повышении уровня высокочувствительного С-реактивного белка выше 10,05 мг/л. Introduction. Despite significant advances in modern cardiology in improving the treatment of patients with coronary heart disease, its clinical form called acute myocardial infarction is a potentially fatal event and cause of death in the adult population. The immune system reacts to acute myocardial infarction and the development of its complications. It is believed that immuno- inflammatory reactions may be the root cause of arrhythmias. However, the mechanisms of these reactions in the development of ventricular arrhythmias remain poorly understood. It seems appropriate to study the state of the systemic inflammatory response in patients with acute myocardial infarction with ventricular arrhythmias. It will allow to assess the role of inflammation in the development of ventricular arrhythmias, as well as to determine the predictor value of the markers of systemic inflammatory response in this group of patients.Purpose. To analyze the levels of markers of systemic inflammatory response among patients with acute myocardial infarction and permanent premature ventricular contractions.Materials and methods. The study involved 351 patients with coronary artery disease (CHD): 185 patients with acute myocardial infarction with stable ST segment elevation and 91 ones with acute myocardial infarction without ST segment elevation; the control group consisted of 75 patients with angina pectoris. The sample of patients was carried out in the period from 2015 to February 2018. In the study, the ST segment elevation myocardial infarction (STEMI) group included 96 (51.9%) residents of the city and 89 (48.1%) ones of the village; the non-ST segment elevation myocardial infarction (NSTEMI) group consisted of 42 (46.2%) residents of the city and 49 (53.8%) ones of the village. The groups were comparable in the proportion of patients from the city and village. All the surveyed persons were comparable in age, social status and sex (the ratio of men and women was 4 to 1).The levels of the acute myocardial infarction biomarkers were determined at the first contact. The blood was taken 24 hours after the onset of clinical manifestations of AMI to determine the biomarkers of inflammation.The premature ventricular contractions (PVCs) were identified with the help of Holter ECG monitoring that lasted for 24 hours. Identification of the PVCs was conducted in 5 days after STEMI. The PVCs of the 1–2 gradations by B. Lown and heart rate turbulence were the criteria for inclusion in the study. Results. The highest level of high-sensitivity C-reactive protein (hs-CRP) was in the group of STEMI patients – 10.63 [9.20–13.44] mg/l and noticeably exceeded the level of this indicator in the group of NSTEMI patients – 8.47 [7.05–10.61] mg/l (p<0.05). In comparison with the group of patients with stable CHD, where the level of hs-CRP was 4.78 [3.60–6.45] mg/l, in the group of patients with STEMI, its level was 2.3 times higher (p<0.05). The hs-CRP level in patients with STEMI with premature ventricular contractions was 11.82 [9.86; 14.00] mg/l, and it was significantly higher than 9,67 [7.43; 12.00] mg/l in the group STEMI without PVCs (p<0.05). The hs-CRP had the largest area under the ROC curve (AUC=0.695, 95% CI 0.624–0.761) among the analyzed markers of immuno-inflammatory response. At the cut-off point >10.05 mg/l, the sensitivity was 70.25% and specificity was 64.06%. The relative risk of occurrence of PVCs in patients with STEMI for hs-CRP >10.05 mg/l was 1.646, 95% CI 1.273–2.129.Conclusions. The systemic inflammatory response behind the values of hs-CRP, tumor necrosisfactor-α, and interleukin-6 levels are more pronounced in patients with STEMI than in those with NSTEMI. The relative risk of premature ventricular contractions increases by 1.646 times in patients with acute myocardial infarction with the increase of the level of hs-CRP higher than 10.05 mg/l.
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Lowell, J. E., M. F. Overholt, B. N. Harsh, C. A. Stahl, A. C. Dilger, and D. D. Boler. "Relationships among early postmortem loin quality and aged loin and pork chop quality characteristics between barrows and gilts." Translational Animal Science 1, no. 4 (December 1, 2017): 607–19. http://dx.doi.org/10.2527/tas2017.0074.

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Abstract Rapid assessment of pork quality by packers necessitates using early postmortem (∼1 d) traits as an indication of aged pork quality (∼14 d). Efforts have been made to develop a grading system based on color and marbling of the ventral side of boneless loins. In order for this system to be successful, there must be a correlation between early postmortem quality traits observed by packers and the same traits observed by consumers after aging. However, the strength and direction of those correlations are unclear. It is also unknown if the correlations between early and aged postmortem quality differ between barrows (B) and gilts (G). Therefore, the objectives were to determine correlations between early postmortem loin quality characteristics and aged loin quality characteristics, and determine if those correlations differed between barrows and gilts. Early postmortem (∼1 d) quality traits included: instrumental and subjective color, marbling and firmness, and loin pH on the ventral surface of the loin. Loins were aged until 14 d postmortem in vacuum packages. Aged quality traits included traits evaluated early as well as shear force and cook loss. Correlations were compared between barrows and gilts using a Fisher's z test. Overall, early subjective firmness scores of barrows were greater (P &lt; 0.001) than those of gilts. No other early quality traits differed between sexes. Early pH was correlated with aged pH (r = 0.80 B; 0.75 G), ventral lightness (r = –0.57 B; –0.54 G), ventral yellowness (r = –0.55 B; –0.55 G), subjective ventral color (r = 0.55, B; 0.41 G), and subjective chop color (r = 0.42 B; 0.44 G). Correlations of early pH and aged quality did not differ between sexes. Early lightness was correlated with aged ventral pH (r = –0.56) and subjective color (r = –0.39) in barrows but not gilts (P ≤ 0.04). Early lightness was correlated with aged lightness (r = 0.60 B; 0.51 G) and yellowness (r = 0.49 B; 0.55 G), but was not correlated with to any aged chop quality traits. Early marbling was correlated with ventral color (r = 0.42) in barrows and ventral marbling (r = 0.67 B; 0.66 G) and chop marbling (r = 0.57 B; 0.59 G) in barrows and gilts. In summary, early pH and lightness were correlated with aged quality characteristics and correlations rarely differed between barrows and gilts. Sex does not need to be accounted for when relating early and aged quality characteristics.
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Dissertations / Theses on the topic "Lown, B"

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Cuadrado, Regina Aznar. "Binarity and the origin of subdwarf B stars." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.483466.

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Cousins, Derek John. "Excitations in '3HE-B at ultra-low temperatures." Thesis, Lancaster University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364359.

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鍾厚添 and Hau-tim Chung. "Low level hepatitis B virus carriers: its detection by polymerase chain reaction based assays and its clinicalsignificance." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B31981616.

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Shaw, Neil Scott. "Experiments in superfluid '3He-B at ultra-low temperatures." Thesis, Lancaster University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242873.

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Bonnefoy, Jean-Yves. "The low affinity receptor for IgE on human B lymphocytes : detection, biochemical characterization and regulation." Lyon 1, 1987. http://www.theses.fr/1987LYO1T147.

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Chung, Hau-tim. "Low level hepatitis B virus carriers : its detection by polymerase chain reaction based assays and its clinical significance /." Hong Kong : University of Hong Kong, 1995. http://sunzi.lib.hku.hk/hkuto/record.jsp?B17537873.

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Rahm, Andreas. "Quantum turbulence in ³He-B at ultra-low temperatures." Thesis, Lancaster University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289041.

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De, Faria Sergio Manuel Maciel. "Very low bit rate video coding using geometric transform motion compensation." Thesis, University of Essex, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309768.

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Kratzert, Daniel. "Charge Density Distribution in Low-Valent Tetrels." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://hdl.handle.net/11858/00-1735-0000-001C-63A3-B.

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Woods, Nathan Michael. "PHASE-LOCKED PIV INVESTIGATION OF THE EFFECTS OF THE BLOWING RATIO OF A PULSED VORTEX GENERATOR JET IN A LOW-PRESSURE TURBINE." Wright State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=wright1190066085.

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Books on the topic "Lown, B"

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1934-, McFarlane Brian, ed. The British 'B' film. New York: British Film Institute, 2009.

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Surveys, Institute for Resource Development Demographic and Health. Model 'B' questionnaire: With commentary for low contraceptive prevalence countries. Calverton, Md: Macro International, 1995.

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Institute for Resource Development. Demographic and Health Surveys. Model 'B' questionnaire: With commentary for low contraceptive prevalence countries. Columbia: Institute for Resource Development, 1990.

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Institute for Resource Development. Demographic and Health Surveys. Model 'B' questionnaire: With commentary for low contraceptive prevalence countries. Columbia: Institute for Resource Development, Westinghouse Electric Corporation, 1987.

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Institute for Resource Development. Demographic and Health Surveys. Model 'B' questionnaire: With additional health questions and commentary for low contraceptive prevalence countries. Columbia: Institute for Resource Development, Westinghouse Electric Corporation, 1987.

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Prescription for survival: A doctor's journey to end nuclear madness. San Francisco, Calif: Berrett-Koehler Publishers, 2008.

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Connolly, Stuart. The effects of zinc low pressure pack sublimation on Fe and Nd-Fe-B powders. Birmingham: University of Birmingham, 1997.

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Ghaderi, Abbas Ali. Functional study of the low affinity IgE receptor (Fc[epsilon]RII/CD23) on human B lymphocytes. Birmingham: University of Birmingham, 1990.

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World War II B-24 "Snoopers": Low level anti-shipping night bombers in the Pacific theater. [United States: S.M. Perrone], 2001.

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Perrone, Stephen M. World War II B-24 "Snoopers": Low level anti-shipping night bombers in the Pacific theater. [United States: S.M. Perrone], 2001.

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Book chapters on the topic "Lown, B"

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Sesto, Fred. "Welcher wesentliche Einwand wird gegen die Klassifikation ventrikulärer Arrhythmien nach B. Lown erhoben?" In Arrhythmie-Kompendium IV, 60. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-93378-3_38.

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Zhirkov, Igor. "Appendix B. Using Make." In Low-Level Programming, 409–13. Berkeley, CA: Apress, 2017. http://dx.doi.org/10.1007/978-1-4842-2403-8_19.

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Lee, Peter J. "Introduction to Section B: Low-Temperature Superconductors." In Handbook of Superconductivity, 131. 2nd ed. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780429179181-20.

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Arcaini, Paolo, Angelo Gargantini, and Elvinia Riccobene. "AsmetaSMV: A Way to Link High-Level ASM Models to Low-Level NuSMV Specifications." In Abstract State Machines, Alloy, B and Z, 61–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-11811-1_6.

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Kenny, J. J., A. Lustig, and D. L. Longo. "Positive Selection of Low Affinity Autoreactive B Cells." In Current Topics in Microbiology and Immunology, 39–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57284-5_5.

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González-Serrano, J. I., C. Benn, R. Carballo, S. F. Sánchez, and M. Vigotti. "B-K Colours of Low-Luminosity Radio Quasars." In ESO Astrophysics Symposia, 260–65. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-540-69648-3_48.

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Bonnet-Bidaud, J. H., and M. van der Klis. "COS-B X-Ray Observations of Cygnus X-3." In Cataclysmic Variables and Low-Mass X-Ray Binaries, 147–50. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-5319-2_19.

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Giles, Alexander J., S. Dai, Chase T. Ellis, J. C. Owrutsky, J. G. Tischler, O. J. Glembocki, F. J. Bezares, et al. "Low-Loss Phonon Polaritons in Nanostructured Dielectrics." In NATO Science for Peace and Security Series B: Physics and Biophysics, 511–12. Dordrecht: Springer Netherlands, 2017. http://dx.doi.org/10.1007/978-94-024-0850-8_54.

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Kiihamäki, Jyrki, Hannu Kattelus, Martti Blomberg, Riikka Puurunen, Mari Laamanen, Panu Pekko, Jaakko Saarilahti, Heini Ritala, and Anna Rissanen. "Low-Temperature Processes for MEMS Device Fabrication." In NATO Science for Peace and Security Series B: Physics and Biophysics, 167–78. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-3807-4_13.

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LuŽnik, Janko, Janez Pirnat, Vojko JazbinŠek, Zvonko Trontelj, TomaŽ Apih, Alan GregoroviČ, Robert Blinc, and Janez Seliger. "Polarization Enhanced Nqr Detection at Low Frequencies." In NATO Science for Peace and Security Series B: Physics and Biophysics, 41–56. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-3062-7_3.

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Conference papers on the topic "Lown, B"

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Rupsis, Joseph. "Low-Energy, High-Intensity Muon Beam (LEHIM-B)." In Low-Energy, High-Intensity Muon Beam (LEHIM-B). US DOE, 2021. http://dx.doi.org/10.2172/1826161.

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Barletta, William A. "Radiation from wigglers in the low energy ring of an asymmetric B factory." In Rare and exclusive b. AIP, 1992. http://dx.doi.org/10.1063/1.42626.

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Wright, B. K., and R. V. Hawkes. "Case Study Production Optimization Shunda Rundle B Pool." In Low Permeability Reservoirs Symposium. Society of Petroleum Engineers, 1989. http://dx.doi.org/10.2118/18965-ms.

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Windhorst, R., S. Odewahn, S. Cohen, C. Burg, R. de Jong, S. Driver, R. Marzke, A. Tyson, and I. Dell’ Antonio. "The HST/WFPC2 B-band galaxy counts vs. type for 19≲B≲29 mag." In The ultraviolet universe at low and high redshift. AIP, 1997. http://dx.doi.org/10.1063/1.53796.

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Kopu, J., V. B. Eltsov, A. P. Finne, M. Krusius, and G. E. Volovik. "NMR Response of a Vortex Tangle in Rotating 3He-B." In LOW TEMPERATURE PHYSICS: 24th International Conference on Low Temperature Physics - LT24. AIP, 2006. http://dx.doi.org/10.1063/1.2354659.

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Wada, Y., Y. Aoki, M. Saitoh, R. Nishida, R. Nomura, and Y. Okuda. "Pressure Dependence of the Transverse Acoustic Impedance of Superfluid 3He-B." In LOW TEMPERATURE PHYSICS: 24th International Conference on Low Temperature Physics - LT24. AIP, 2006. http://dx.doi.org/10.1063/1.2354619.

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Wang, Suwen, R. P. Farley, J. H. Goebel, G. M. Keiser, J. A. Lipa, and J. P. Turneaure. "Initial Evaluation of the GP-B Cryogenic Telescope Performance in Orbit." In LOW TEMPERATURE PHYSICS: 24th International Conference on Low Temperature Physics - LT24. AIP, 2006. http://dx.doi.org/10.1063/1.2355327.

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Bradley, D. I., S. N. Fisher, A. M. Guénault, R. P. Haley, H. Martin, G. R. Pickett, J. E. Roberts, and V. Tsepelin. "A Levitated Droplet of Superfluid 3He-B Entirely Surrounded by 3He-A." In LOW TEMPERATURE PHYSICS: 24th International Conference on Low Temperature Physics - LT24. AIP, 2006. http://dx.doi.org/10.1063/1.2354621.

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Dmitriev, V. V., N. Mulders, V. V. Zavjalov, and D. E. Zmeev. "CW NMR Measurements of the Leggett Frequency in 3He-B in Aerogel." In LOW TEMPERATURE PHYSICS: 24th International Conference on Low Temperature Physics - LT24. AIP, 2006. http://dx.doi.org/10.1063/1.2354677.

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Hiremath, M. N., B. M. Angadi, and Naveen N. Desai. "Design and Fabrication of Indigenous Low Cost Water Filter Using Activated Carbon Prepared from Low Cost Materials." In 2020 IEEE Bangalore Humanitarian Technology Conference (B-HTC). IEEE, 2020. http://dx.doi.org/10.1109/b-htc50970.2020.9297905.

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Reports on the topic "Lown, B"

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Heifets, S., and A. Novokhatski. Study of the Low Momentum Compaction B-factory. Office of Scientific and Technical Information (OSTI), September 2005. http://dx.doi.org/10.2172/878420.

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Walter, E. J. B Plant low level waste system integrity assessment report. Office of Scientific and Technical Information (OSTI), September 1995. http://dx.doi.org/10.2172/447984.

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Walter, E. J. B Plant low level waste system integrity assessment plan. Office of Scientific and Technical Information (OSTI), September 1994. http://dx.doi.org/10.2172/10191822.

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Jeffery-Schwikkard, David, Timothy Lomas, Phalasha Nagpal, Ellen Morgan, and Junying Li. A systematic review of the empirical literature on character development in individuals in low- and middle-income countries. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2022. http://dx.doi.org/10.37766/inplasy2022.10.0117.

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Review question / Objective: How has character development in individuals been studied in low-income and middle-income countries? Constituent questions: 1. Which populations are being studied? a. Which demographics? (gender, age, income, minorities, disabilities) 2. What aspects of character development are being studied? a. Including for interventions – intervention design, duration, dosage. b. How is character development itself conceptualized and operationalized? 3. What are the contexts of these studies? a. Which countries? b. For interventions – what is the site of the intervention? (e.g., schools, communities, religious institutions) 4. What are the methodological designs of these studies? a. What measurement tools are used in these studies? i. Are these developed for use (or otherwise adapted for use) in these regions? If so, how? b. What is the quality of these studies? 5. What are the key findings of these studies? 6. Who is funding and conducting this research?
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Beam, T. G. B Plant complex hazardous, mixed and low level waste certification plan. Office of Scientific and Technical Information (OSTI), November 1994. http://dx.doi.org/10.2172/10104961.

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Bigl, Matthew, Samuel Beal, and Charles Ramsey. Determination of residual low-order detonation particle characteristics from Composition B mortar rounds. Engineer Research and Development Center (U.S.), August 2022. http://dx.doi.org/10.21079/11681/45260.

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Empirical measurements of the spatial distribution, particle-size distribution, mass, morphology, and energetic composition of particles from low-order (LO) detonations are critical to accurately characterizing environ-mental impacts on military training ranges. This study demonstrated a method of generating and characterizing LO-detonation particles, previously applied to insensitive munitions, to 81 mm mortar rounds containing the conventional explosive formulation Composition B. The three sampled rounds had estimated detonation efficiencies ranging from 64% to 82% as measured by sampled residual energetic material. For all sampled rounds, energetic deposition rates were highest closer to the point of detonation; however, the mass per radial meter varied. The majority of particles (>60%), by mass, were <2 mm in size. However, the spatial distribution of the <2 mm particles from the point of detonation varied be-tween the three sampled rounds. In addition to the particle-size-distribution results, several method performance observations were made, including command-detonation configurations, sampling quality control, particle-shape influence on laser-diffraction particle-size analysis (LD-PSA), and energetic purity trends. Overall, this study demonstrated the successful characterization of Composition B LO-detonation particles from command detonation through combined analysis by LD-PSA and sieving.
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Lichter, Amnon, Gopi K. Podila, and Maria R. Davis. Identification of Genetic Determinants that Facilitate Development of B. cinerea at Low Temperature and its Postharvest Pathogenicity. United States Department of Agriculture, March 2011. http://dx.doi.org/10.32747/2011.7592641.bard.

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Botrytis cinerea is the postharvest pathogen of many agricultural produce with table grapes, strawberries and tomatoes as major targets. The high efficiency with which B. cinerea causes disease on these produce during storage is attributed in part due to its exceptional ability to develop at very low temperature. Our major goal was to understand the genetic determinants which enable it to develop at low temperature. The specific research objectives were: 1. Identify expression pattern of genes in a coldenriched cDNA library. 2. Identify B. cinerea orthologs of cold-induced genes 3. Profile protein expression and secretion at low temperature on strawberry and grape supplemented media. 4. Test novel methods for the functional analysis of coldresponsive genes. Objective 1 was modified during the research because a microarray platform became available and it allowed us to probe the whole set of candidate genes according to the sequence of 2 strains of the fungus, BO5.10 and T4. The results of this experiment allowed us to validate some of our earlier observations which referred to genes which were the product of a SSH suppression-subtraction library. Before the microarray became available during 2008 we also analyzed the expression of 15 orthologs of cold-induced genes and some of these results were also validated by the microarray experiment. One of our goals was also to perform functional analysis of cold-induced genes. This goal was hampered for 3 years because current methodology for transformation with ‘protoplasts’ failed to deliver knockouts of bacteriordopsin-like (bR) gene which was our primary target for functional analysis. Consequently, we developed 2 alternative transformation platforms, one which involves an air-gun based technique and another which involves DNA injection into sclerotia. Both techniques show great promise and have been validated using different constructs. This contribution is likely to serve the scientific community in the near future. Using these technologies we generated gene knockout constructs of 2 genes and have tested there effect on survival of the fungus at low temperature. With reference to the bR genes our results show that it has a significant effect on mycelial growth of the B. cinerea and the mutants have retarded development at extreme conditions of ionic stress, osmotic stress and low temperature. Another gene of unknown function, HP1 is still under analysis. An ortholog of the yeast cold-induced gene, CCH1 which encodes a calcium tunnel and was shown to be cold-induced in B. cinerea was recently cloned and used to complement yeast mutants and rescue them from cold-sensitivity. One of the significant findings of the microarray study involves a T2 ribonuclease which was validated to be cold-induced by qPCR analysis. This and other genes will serve for future studies. In the frame of the study we also screened a population of 631 natural B. cinerea isolates for development at low temperature and have identified several strains with much higher and lower capacity to develop at low temperature. These strains are likely to be used in the future as candidates for further functional analysis. The major conclusions from the above research point to specific targets of cold-induced genes which are likely to play a role in cold tolerance. One of the most significant observations from the microarray study is that low temperature does not induce ‘general stress response in B. cinerea, which is in agreement to its exceptional capacity to develop at low temperature. Due to the tragic murder of the Co-PI Maria R. Davis and GopiPodila on Feb. 2010 it is impossible to deliver their contribution to the research. The information of the PI is that they failed to deliver objective 4 and none of the information which relates to objective 3 has been delivered to the PI before the murder or in a visit to U. Alabama during June, 2010. Therefore, this report is based solely on the IS data.
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Wakai, E., K. Shiba, T. Sawai, N. Hashimoto, J. P. Robertson, and R. L. Klueh. Microstructural evolution of HFIR-irradiated low activation F82H and F82H-{sup 10}B steels. Office of Scientific and Technical Information (OSTI), March 1998. http://dx.doi.org/10.2172/335390.

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Hall, Douglas. Water Energy Resources of the United States with Emphasis on Low Head/Low Power Resources: Appendix B - Assessment Results by State. Office of Scientific and Technical Information (OSTI), April 2004. http://dx.doi.org/10.2172/1218174.

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Hall, Douglas. Water Energy Resources of the United States with Emphasis on Low Head/Low Power Resources: Appendix B - Assessment Results by State. Office of Scientific and Technical Information (OSTI), April 2004. http://dx.doi.org/10.2172/1218175.

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