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Garrido, Juan Manuel. "Jean-Luc Nancy’s Concept of Body." Epoché 14, no. 1 (2009): 189–211. http://dx.doi.org/10.5840/epoche200914129.
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Aleksiejunaite, Monika, Antanas Sidlauskas, and Arunas Vasiliauskas. "Effect of Rebonding on the Bond Strength of Orthodontic Tubes: A Comparison of Light Cure Adhesive and Resin-Modified Glass Ionomer Cement In Vitro." International Journal of Dentistry 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/8415979.
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The purpose of this study was to determine the impact of different enamel preparation procedures and compare light cure composite (LCC) and resin-modified glass ionomer (RMGI) on the bond strength of orthodontic metal tubes rebonded to the enamel. Twenty human molars were divided into two groups (n=10). Tubes were bonded using LCC (Transbond XT) in group 1 and RMGI (Fuji Ortho LC) in group 2. The tubes in each group were bonded following manufacturers’ instructions (experiment I) and then debonded using testing machine. Then, the same brackets were sandblasted and rebonded twice. Before the first rebonding, the enamel was cleaned using carbide bur (experiment II) and before second rebonding, it was cleaned using carbide bur and soda blasted (experiment III). Mann–Whitney and Wilcoxon signed-rank tests showed no significant difference between RMGI and LCC bond strengths in case of normal bonding and rebonding, when enamel was cleaned using carbide bur before rebonding. Enamel soda blasting before rebonding significantly increased RMGI tensile bond strength value compared to LLC (p<0.05). LCC and RMGI (especially RMGI) provide sufficient bond strengths for rebonding of molar tubes, when residual adhesive from previous bonding is removed and enamel soda blasted.
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Filler, Jule, Ricarda von Krüchten, Nina Wawro, Lisa Maier, Roberto Lorbeer, Johanna Nattenmüller, Barbara Thorand, et al. "Association of Habitual Dietary Intake with Liver Iron—A Population-Based Imaging Study." Nutrients 14, no. 1 (December 28, 2021): 132. http://dx.doi.org/10.3390/nu14010132.
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Iron-related disorders of the liver can result in serious health conditions, such as liver cirrhosis. Evidence on the role of modifiable lifestyle factors like nutrition in liver iron storage is lacking. Thus, we aimed to assess the association of habitual diet with liver iron content (LIC). We investigated 303 participants from the population-based KORA-MRI study who underwent whole-body magnetic resonance imaging (MRI). Dietary habits were evaluated using repeated 24 h food lists and a food frequency questionnaire. Sex-stratified multiple linear regression models were applied to quantify the association between nutrition variables of interest and LIC, adjusting for liver fat content (LFC), energy intake, and age. Mean age of participants was 56.4 ± 9.0 years and 44.2% were female. Mean LIC was 1.23 ± 0.12 mg/g dry weight, with higher values in men than in women (1.26 ± 0.13 and 1.20 ± 0.10 mg/g, p < 0.001). Alcohol intake was positively associated with LIC (men: β = 1.94; women: β = 4.98, p-values < 0.03). Significant negative associations with LIC were found for fiber (β = −5.61, p < 0.001) and potassium (β = −0.058, p = 0.034) for female participants only. Furthermore, LIC was highly correlated with liver fat content in both sexes. Our findings suggests that there are sex-specific associations of habitual dietary intake and LIC. Alcohol, fiber, and potassium may play a considerable role in liver iron metabolism.
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Birks, Chelsea. "Body problems: new extremism, Descartes and Jean-Luc Nancy." New Review of Film and Television Studies 13, no. 2 (February 23, 2015): 131–48. http://dx.doi.org/10.1080/17400309.2015.1009355.
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Rodrigues, António M. M., and Andy Gardner. "Simultaneous failure of two sex-allocation invariants: implications for sex-ratio variation within and between populations." Proceedings of the Royal Society B: Biological Sciences 282, no. 1810 (July 7, 2015): 20150570. http://dx.doi.org/10.1098/rspb.2015.0570.
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Local mate competition (LMC) occurs when male relatives compete for mating opportunities, and this may favour the evolution of female-biased sex allocation. LMC theory is among the most well developed and empirically supported topics in behavioural ecology, clarifies links between kin selection, group selection and game theory, and provides among the best quantitative evidence for Darwinian adaptation in the natural world. Two striking invariants arise from this body of work: the number of sons produced by each female is independent of both female fecundity and also the rate of female dispersal. Both of these invariants have stimulated a great deal of theoretical and empirical research. Here, we show that both of these invariants break down when variation in female fecundity and limited female dispersal are considered in conjunction. Specifically, limited dispersal of females following mating leads to local resource competition (LRC) between female relatives for breeding opportunities, and the daughters of high-fecundity mothers experience such LRC more strongly than do those of low-fecundity mothers. Accordingly, high-fecundity mothers are favoured to invest relatively more in sons, while low-fecundity mothers are favoured to invest relatively more in daughters, and the overall sex ratio of the population sex ratio becomes more female biased as a result.
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Bansal, Sandeep, and Neha Chauhan. "Foreign Body (Bullet) in Maxilla." Journal of Postgraduate Medicine, Education and Research 50, no. 1 (2016): 30–32. http://dx.doi.org/10.5005/jp-journals-10028-1188.
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ABSTRACT Foreign bodies in the maxillary sinus are not unusual findings. Many cases have been reported so far with foreign bodies like tooth, dental amalgam, chopstick, matchstick, guttapercha point, etc. This paper reports a case of bullet injury with a lodged bullet in maxillary sinus and was retrieved by Caldwell-Luc approach with no intraoperative and postoperative complications. How to cite this article Bansal S, Chauhan N, Gupta AK. Foreign Body (Bullet) in Maxilla. J Postgrad Med Edu Res 2016;50(1):30-32.
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Lin, Yu-Chuan, Hong-Wen Chen, Yu-Cheng Kuo, Ya-Fang Chang, Yi-Jang Lee, and Jeng-Jong Hwang. "Therapeutic Efficacy Evaluation of Curcumin on Human Oral Squamous Cell Carcinoma Xenograft Using Multimodalities of Molecular Imaging." American Journal of Chinese Medicine 38, no. 02 (January 2010): 343–58. http://dx.doi.org/10.1142/s0192415x10007890.
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Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity; however the treatment approaches are still unsatisfactory. We used a luciferase-transfected animal model to evaluate the therapeutic effects of curcumin. Human oral squamous cell carcinoma SAS cell line was stably transfected with luc gene, named SAS/luc cells. For the in vivo study, they were inoculated subcutaneously to 6-week-old male NOD/SCID mice which were separated into four groups for intraperitoneal injection (i.p.) of curcumin: control, daily with 35 mg/kg, 70 mg/kg every 2 days, and 100 mg/kg every 3 days. We applied SAS/luc bearing animal model and bioluminescent imaging (BLI) to study the inhibition effect of curcumin on tumor growth. The cytotoxic effect of curcumin on SAS/luc cells was mainly at G2/M phase and a significant dose dependent increase of the apoptotic SAS/luc cells as represented by sub-G1 phase was shown. Therapeutic efficacy evaluated by both caliper assay and BLI showed a significant difference between curcumin-treated mice and the controls (p < 0.01). The significant inhibition effects of curcumin on the proliferation and the growth of human OSCC are observed both in vitro and in vivo. No significant body weight change (i.e. within 20%) was observed in all SAS/luc-bearing mice with or without curcumin treatment. This SAS/luc human OSCC bearing animal model combined with multimodalities of molecular imaging permits a sensitive and non-invasive approach to evaluate the therapeutic efficacy in vivo.
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Perpich, Diane. "Corpus Meum: Disintegrating Bodies and the Ideal of Integrity." Hypatia 20, no. 3 (2005): 75–91. http://dx.doi.org/10.1111/j.1527-2001.2005.tb00487.x.
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This essay shows that Jean-Luc Nancy's reconceptualization of corporeality in such texts as L'Intrus and Corpus can be an important ally to feminist theories of body. I introduce Nancy's ontology and argue that his rejection of the unified, integrated body of humanist discourses in favor of dis-integrated bodies constituted by multiple alterities and his consequent reinterpretation of body as a “being-exscribed” begin the task of thinking bodies beyond traditional dualisms and their ahistorical and rationalist frameworks. I then address three potential criticisms of Nancy's work and suggest that though there may be reasons to move cautiously in adopting the framework he provides, his work harbors resources directly beneficial to critiques of prevailing forms of gender normativity.Quel étrange moi!—Jean-Luc Nancy, Corpus
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Merkley, Cari. "The Library of Congress, Dewey Decimal, and Universal Decimal Classification Systems are Incomplete and Unsystematic." Evidence Based Library and Information Practice 6, no. 4 (December 15, 2011): 134. http://dx.doi.org/10.18438/b8qk7s.
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Objective – To determine the extent to which knowledge is currently addressed by the Library of Congress (LCC), Dewey Decimal (DDC), and Universal Decimal (UDC) classification systems.
Design – Comparative analysis of the LCC, DDC, and UDC systems using Zin’s 10 Pillars of Knowledge.
Setting – The Faculty of Philosophy and Science at a Brazilian university.
Subjects – Forty one subject-related classes and 386 subclasses from the first two levels of the LCC, DDC, and UDC systems.
Methods – To evaluate the LCC, DDC, and UDC systems, the researchers employed the 10 Pillars of Knowledge, a “hierarchical knowledge tree” developed by the lead author of this study (p. 878). According to the authors, the 10 Pillars of Knowledge seek to illustrate relationships between fields of knowledge while capturing their breadth. The first level of the Pillars consists of the following categories: Knowledge, Supernatural, Matter and Energy, Space and Earth, Nonhuman Organizations, Body and Mind, Society, Thought and Art, Technology, and History. Each of the 10 Pillars is further subdivided, resulting in a four level hierarchical structure of 76 categories. Of the 76 categories, 55 are unique subject areas. A selection of subject-based classes and subclasses from the first two levels of the LCC, DDC, and UDC systems were then mapped to the relevant subclasses within the Pillars. Analysis was limited to the first two levels of LCC, DDC, and UDC, except for the LCC categories of BF and BL where further subclasses were analyzed. Classes or subclasses in LCC, DDC, or UDC that were not subject based (for example, those based on publication type) were excluded from the study. In total, 41 main classes and 386 subclasses from LLC, DDC, and UDC were categorized using the 10 Pillars.
Main Results – The LLC, DDC, and UDC systems were deemed to be complete and systematic in their coverage of only three of the 10 Pillars: Matter and Energy, Thought and Art, and History. This means that there was at least one class or subclass in each of the three systems that corresponded to the subclasses in these pillars. The remaining seven pillars were only partially covered by the three systems to varying degrees. For example, the coverage of religion in LCC and DDC show evidence of a bias towards Christianity and incomplete coverage of other faiths. In addition to the lack of completeness in terms of subject coverage, the researchers found inconsistencies and problems with how relationships between subjects were illustrated by the systems. For example, botany should be a subclass of biology, but the subjects occupy the same level in the LCC, DDC, and UDC systems. Researchers also noted cases where subclasses on the same level were not mutually exclusive e.g., the BR (Christianity) and BS (The Bible) subclasses in LCC. Overall, LLC performed slightly better than DDC or UDC, covering 47 of the 55 unique subject categories in the 10 Pillars. It was followed by UDC with 44 out of 55, and DDC with 43 out of 55. Some of the 55 unique subject categories in the 10 Pillars system were not represented by any of the systems: 3 subclasses under Society (Society at Large – Area Based, Social Groups – Age, and Social Groups – Ethnicity), 2 under Technology (Technologies – Materials and Technologies – Processes), and 1 under Foundations (Methodology).
Conclusion – The researchers conclude that none of the three major classification systems analyzed provides complete and systematic coverage of the world of knowledge, and call for the library community to move to new systems, such as the 10 Pillars of Knowledge.
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Tamai, Hayato, Hiroki Yamaguchi, Kazuo Dan, and Koiti Inokuchi. "Inhibition Of S100A6 Induces Graft Versus Leukemia Effects In MLL/AF4-Positive ALL In Human PBMC-SCID Mice." Blood 122, no. 21 (November 15, 2013): 2016. http://dx.doi.org/10.1182/blood.v122.21.2016.2016.
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Mixed-lineage leukemia (MLL)/AF4-positive acute lymphoblastic leukemia (ALL) is associated with poor prognosis even after allogeneic hematopoietic stem cell transplantation (allo-HSCT). The resistance to graft-versus-leukemia (GVL) effects may be responsible for the poor effect of allo-HSCT on MLL-AF4-positive ALL. Cytotoxic effector mechanisms mediated by tumor necrosis factor-alpha (TNF-a) was reported to contribute to the GVL effect. We reported previously that MLL/AF4-positive ALL shows resistance to TNF-a, which is the main factor in GVL effect, by upregulation of S100A6 expression followed by interference with the p53-caspase 8-caspase 3 pathway in vitro. We examined whether inhibition of S100A6 can induce an effective GVL effect on MLL/AF4-positive ALL in a mouse model. To examine the long-term effects of inhibition of S100A6,MLL/AF4-positive ALL cell lines (SEM) transduced with lentiviral vectors expressing both S100A6 siRNA and luciferase (SEM-Luc-S100A6 siRNA) were produced. SEM-Luc-S100A6 siRNA cells and SEM-Luc-control siRNA cells were injected into groups of five SCID mice (1×107/body). After confirmation of engraftment of SEM cells by in vivo imaging, the mice in each group were injected with 4.8×107 human peripheral blood mononuclear cells (PBMCs). Although there were no significant differences between the serum concentrations of human-TNF-a after injection of human PBMCs of SEM-Luc-S100A6 siRNA injected mice and those of SEM-Luc-control siRNA injected mice (P=0.95), SEM-Luc-S100A6 siRNA-injected mice showed significantly longer survival periods than SEM-Luc-control siRNA-injected mice (P = 0.002). SEM-Luc-S100A6 siRNA-injected mice showed significantly slower tumor growth than those injected with SEM-Luc-control siRNA (P < 0.0001). These results suggested that inhibition of S100A6 may be a promising therapeutic target for MLL/AF4-positive ALL in combination with allo-HSCT because it induce effective GVL effectson MLL/AF4-positive ALL which is resistant to GVL effects. Disclosures: No relevant conflicts of interest to declare.
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Adiseshaiah, Pavan P., Nimit L. Patel, Lilia V. Ileva, Joseph D. Kalen, Diana C. Haines, and Scott E. McNeil. "Longitudinal Imaging of Cancer Cell Metastases in Two Preclinical Models: A Correlation of Noninvasive Imaging to Histopathology." International Journal of Molecular Imaging 2014 (March 3, 2014): 1–13. http://dx.doi.org/10.1155/2014/102702.
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Metastatic spread is the leading cause of death from cancer. Early detection of cancer at primary and metastatic sites by noninvasive imaging modalities would be beneficial for both therapeutic intervention and disease management. Noninvasive imaging modalities such as bioluminescence (optical), positron emission tomography (PET)/X-ray computed tomography (CT), and magnetic resonance imaging (MRI) can provide complementary information and accurately measure tumor growth as confirmed by histopathology. Methods. We validated two metastatic tumor models, MDA-MD-231-Luc and B16-F10-Luc intravenously injected, and 4T1-Luc cells orthotopically implanted into the mammary fat pad. Longitudinal whole body bioluminescence imaging (BLI) evaluated metastasis, and tumor burden of the melanoma cell line (B16-F10-Luc) was correlated with (PET)/CT and MRI. In addition, ex vivo imaging evaluated metastasis in relevant organs and histopathological analysis was used to confirm imaging. Results. BLI revealed successful colonization of cancer cells in both metastatic tumor models over a 4-week period. Furthermore, lung metastasis of B16-F10-Luc cells imaged by PET/CT at week four showed a strong correlation (R2=0.9) with histopathology. The presence and degree of metastasis as determined by imaging correlated (R2=0.7) well with histopathology findings. Conclusions. We validated two metastatic tumor models by longitudinal noninvasive imaging with good histopathology correlation.
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Cohen, Rona. "Jean-Luc Nancy and the Extension of the Mind." Philosophy Today 63, no. 2 (2019): 347–62. http://dx.doi.org/10.5840/philtoday201985272.
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This essay explores Jean-Luc Nancy’s philosophical return to Cartesian philosophy, specifically to Descartes’s preoccupation with the relation of mind and body, as a fertile ground from which to develop an ontology of the body in (1992). It explores Nancy’s reasons for revisiting the Cartesian thinking framework, which on the face of it, is of little value to an ontology of the body. I argue that Descartes’s impasse in accounting for both mind/body dualism and their union constitutes Nancy’s point of departure in constructing an ontology of the body in , thereby transforming Descartes’s impasse into a productive aporia, in the Derridean sense of the term. To fully understand the significance of the notion of “relation” in Nancy’s’ philosophy, I turn to his reading of Lacan’s famous aphorism “there is no sexual relation” and explore its ontological implications.
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Xie, Yimin, Xudong Chen, Kai Zhang, Sheng Cui, and Gongxia Zhang. "Elucidation of lignin and polysaccharide linkages in wheat straw by 2H/13C isotopic tracer." BioResources 18, no. 1 (November 17, 2022): 550–69. http://dx.doi.org/10.15376/biores.18.1.550-569.
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To elucidate chemical linkages between lignin and polysaccharides, the aqueous mixed solutions of coniferin-[α-13C], syringin-[α-13C], D-glucose-[6-2H], and phenylalanine ammonia-lyase inhibitor were injected into a living wheat stalk. Internode tissues with high abundance of 2H-13C were collected. The milled wood lignin, lignin-carbohydrate complex (LCC), and residual LCC (R-LCC) with enrichment of 2H-13C were isolated. The 13C and 2H abundances showed that the lignin and polysaccharides of internode tissues were labeled by 13C and 2H, respectively. Analysis with carbon-13 nuclear magnetic resonance (13C-NMR) showed that ketal and benzyl ether bonds were formed between α-C of lignin and carbohydrates. The R-LCC and LCC were further treated with enzymes to obtain enzymatic degraded R-LCC (ED-R-LCC) and enzymatic degraded LCC (ED-LCC). 13C-NMR spectra of ED-LCC showed that the α-C of lignin side chain was combined with 6-C of carbohydrates by ether, ester, and ketal linkages. 1H-NMR differential spectra of ED-LCCs revealed an LC linkage of benzyl ether bond. Glucan-lignin (En-R-GL) and xylan-lignin (En-R-XL) complexes were separated from ED-R-LCC by ionic liquid. A part of lignin α-C was linked to cellulose 6-C by benzyl ether and α-ketal linkages. 13C-NMR spectra of En-R-XL showed there were α-benzyl ether and α-ketal bonds between lignin and xylan.
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Bernabé Argandoña, Lorena Carolina, Salvador Cruz Rambaud, and Joaquín López Pascual. "The Impact of Sustainable Bond Issuances in the Economic Growth of the Latin American and Caribbean Countries." Sustainability 14, no. 8 (April 14, 2022): 4693. http://dx.doi.org/10.3390/su14084693.
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There is beyond any doubt that Latin America is one of the most important emerging markets in the world, which has increased its importance in the last decades. In effect, the issues of green, social, and sustainability (GSS) bonds are gaining more and more importance in the Latin American and the Caribbean (LAC) financial markets. They are specifically focused on raising funding for public expenditure programs that contribute to achieving several objectives, such as climate and environmental projects, energy efficiency, pollution prevention, sustainable agriculture, fishery and forestry, etc. The main objective of this paper is to provide a literature revision of the evolution of the issuance of GSS bonds in the LAC region and to analyze the economic growth of the countries which issue this type of bond. We will apply multiple linear regression to relate the economic growth of some countries of the LAC region with the variables proposed by the IFC Emerging Market Green Bonds Report (2019). It has been shown that the economic growth of the countries in the LAC region that are issuing GSS bonds is significantly related to the Sovereign Green Issuance (Total Planned), the ratio of Private Credit/GDP, and the Rule of Law Index. However, this research has had the limitation of the scarcity of available data in the LAC markets.
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Lundblad, Kristina. "Body text." Tidskrift för litteraturvetenskap 51, no. 1-2 (December 10, 2021): 61–78. http://dx.doi.org/10.54797/tfl.v51i1-2.1723.
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Body text: Typography and the corporeality of literature In one of his fragments, Georg Christoph Lichtenberg explains that German books printed with roman type, instead of the then default gothic type, always give him a feeling that he needs to translate them – evidence, he says, of “the degree to which our concepts are dependent on these signs”. The article elaborates on this thought. It explores the relation between literature, text (abstract and material), and typography, and argues – by means of bibliographical theory, Goethe’s mother, Jean-Luc Nancy, Roman Ingarden, and a diagnostic comparison between hand writing and digital fonts – that the longstanding, idealistic view, within literary criticism and history, of texts’ ‘content’ as independent of books’ and texts’ materiality and form, obstructs scholars’ striving for understand-ing. Text is not only representation; it is also presentation. Text has form, and the form produces meaning.
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Nylander, Filip, Hampus Sunner, Lisbeth Olsson, Paul Christakopoulos, and Gunnar Westman. "Synthesis and enzymatic hydrolysis of a diaryl benzyl ester model of a lignin-carbohydrate complex (LCC)." Holzforschung 70, no. 5 (May 1, 2016): 385–91. http://dx.doi.org/10.1515/hf-2014-0347.
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Abstract Specific degradation of the bonds between lignin and carbohydrates is an important step towards separating individual lignocellulosic biopolymers for sustainable production of materials and chemicals. One of the most established covalent lignin-carbohydrate (LC) interactions is the ester bond between the α- or γ-hydroxyl group of a lignin phenylpropane unit and a glucuronic acid side chain of xylan. In this work, a model of the LC benzyl ester bond was synthesized in a one-pot reaction from a β-O-4 lignin unit and d-glucuronic acid, both from commercial sources. The resulting lignin-carbohydrate complex (LCC) model was unstable in aqueous solution. However, at pH 4, the rate of spontaneous hydrolysis was sufficiently low to allow for enzymatic splitting experiments. The enzymatic hydrolysis of the LC benzyl ester bond of the LCC model was demonstrated by means of the glucuronoyl esterase StGE2 from Sporotrichum thermophile, which showed a preference for erythro forms of the LCC model.
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Zhaparova, A. K. "METAPHORS OF THE BODY IN THE PHILOSOPHY OF JEAN-LUC NANCY: THE SUFFERING BODY." Review of Omsk State Pedagogical University. Humanitarian research, no. 37 (2022): 24–28. http://dx.doi.org/10.36809/2309-9380-2022-37-24-28.
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This article examines the idea of Jean-Luc Nancy about the body, in particular his thesis that we do not have a body, as well as about the subject as a body turned inside out, as an external and infinite influence. The purpose of the article is to consider the ontological and epistemological status of the body, medical practices related to experiences and limitations in the process of transplantation. Nancy “shows” that in the course of bodily metamorphoses, not only new forms of subjectivity are formed, but also “new flesh” is found. Thus, at the boundaries between the natural and the artificial, it becomes possible to think of a fragmented body as what Deleuze and Guattari called “the body without organs”.
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Achmad, Ashfa, Laina Hilma Sari, and Ichwana Ramli. "A study of urban heat island of Banda Aceh City, Indonesia based on land use/cover changes and land surface temperature." Aceh International Journal of Science and Technology 8, no. 1 (May 9, 2019): 41–51. http://dx.doi.org/10.13170/aijst.8.1.13060.
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This article described the spatial and temporal of land surface temperature (LST) patterns in Banda Aceh City, Indonesia, in the context of urban heat island (UHI) phenomenon. Landsat imaginary in 1998 and 2018 was used in this study, which represents the conditions before and after the tsunami. Geographic Information System (GIS) and Remote Sensing (RS) technique were used for data analysis. The 1998 and 2018 LUC maps were derived from remote sensing satellite images using a supervised classification method (maximum likelihood). Both LUC maps contained five categories, namely built-up area, vegetation, water body, vacant land, and wet land. The 1998 LUC map had a kappa coefficient 0.91, while the 2018 LUC map had 0.84. It was found that the built-up area increased by 100%, while the vegetation category fell 50%. The overall mean LST in the study area increased 5.90C between 1998 and 2018, with the highest mean increase in the built-up area category. The study recommends that LST should be taken into consideration in urban planning process to realize sustainable urban development. It also emphasizes the importance of optimizing the availability of green open space to reduce UHI effects and helps in improving the quality of the urban environment.
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Şahin, Yunus Feyyat, Togay Muderris, Sami Bercin, Ergun Sevil, and Muzaffer Kırıs. "Chronic Maxillary Sinusitis Associated with an Unusual Foreign Body: A Case Report." Case Reports in Otolaryngology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/903714.
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Foreign bodies in maxillary sinuses are unusual clinical conditions, and they can cause chronic sinusitis by mucosal irritation. Most cases of foreign bodies in maxillary sinus are related to iatrogenic dental manipulation and only a few cases with non-dental origin are reported. Oroantral fistulas secondary to dental procedures are the most common way of insertion. Treatment is surgical removal of the foreign body either endoscopically or with a combined approach, with Caldwell-Luc procedure if endoscopic approach is inadequate for visualisation. In this case, we present a 24-year-old male patient with unilateral chronic maxillary sinusitis due to a wooden toothpick in left maxillary sinus. The patient had a history of upper second premolar tooth extraction. CT scan revealed sinus opacification with presence of a foreign body in left maxillary sinus extending from the floor of the sinus to the orbital base. The foreign body, a wooden toothpick, was removed with Caldwell-Luc procedure since it was impossible to remove the toothpick endoscopically. There was no obvious oroantral fistula in the time of surgery, but the position of the toothpick made us to think that it was inserted through a previously healed fistula, willingly or accidentally.
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Zawadzki, Ryszard. "The Prayer of Jesus on the Cross." Verbum Vitae 22 (December 14, 2012): 93–110. http://dx.doi.org/10.31743/vv.2051.
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The Passion Narratives in Synoptic Gospels present Jesus on the cross not only as a Messias patiens, but also as a Messias orans. This article constitutes an attempt to show a synoptic picture of the Crucified who prays. In the first part of the article we focus on the nonverbal dimension of Jesus’ prayer on the cross, e.g. on the posture of his body forced by the means of execution and on his laud, inarticulate cry of the agony. In the second part, the subject of the analysis becomes three of seven “last words of Jesus”, that assume the form of prayer: Luc 23,34a; Mt 27,46; Luc 23,46.
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Howells, Christina. "Jean-Luc Nancy and La Peau des images." Body & Society 24, no. 1-2 (March 5, 2018): 166–74. http://dx.doi.org/10.1177/1357034x18760179.
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This article considers Jean-Luc Nancy’s reflections on the nude in painting and photography in the light of his aesthetics, his philosophy of the body and soul, and some of his other writings on portraiture. It explores Nancy’s insistence on skin as the truth behind and beyond which no further meaning waits to be revealed: there are no hidden depths, no secret or sacred truths, nothing is concealed beneath the skin.
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Asaduzzaman, AKM, Md Rafiquzzaman, Mani Lal Aich, Md Abdul Mannan, Md Rabiul Alam, Md Tauhidul Islam, and M. A. Rouf Sarder. "Caldwel-Luc operation without intranasal antrostomy." Bangladesh Journal of Otorhinolaryngology 18, no. 2 (November 24, 2012): 156–60. http://dx.doi.org/10.3329/bjo.v18i2.12007.
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Introduction: Sub-labial antrostomy also known as Caldwel-Luc operation is a well-accepted procedure to remove any diseased mass, organic tissue or non-organic foreign body from maxillary antrum. The proceedings of this operation are though complex but not complicated if done by an expert hand. In addition to sub-labial approach this procedure is followed by an intranasal antrostomy to facilitate future drainage and through which the antral pack is introduced and removed post-operatively.Methods: In our series of 30 patients, we performed the same procedure through sub-labial approach only. No intranasal antrostomy were done. Also we opened the antrum by a small hole made over antero-lateral wall of the antrum.Results: The adopted method decreased the post-operative morbidity and also reduced the period of healing. No patient developed any major complication like oro-antral fistula either on immediate or long term follow-up up to one year. Only one (3.33%) patient had a temporary obstruction in drainage of collection in antrum even after not performing the intranasal antrostomy.Conclusion: Thus we conclude that this modification of Caldwel-Luc operation only through sub-labial approach without performing intranasal antrostomy could be accepted as an innovative procedure for better outcome of the patients as well as its cost-effectiveness DOI: http://dx.doi.org/10.3329/bjo.v18i2.12007 Bangladesh J Otorhinolaryngol 2012; 18(2): 156-160
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Lemos Felicio Agostinho, Cicero Newton, Thais Dias dos Santos, and Leonardo Viana Araújo. "REMOÇÃO DE TERCEIRO MOLAR EM SEIO MAXILAR COM USO DE TÉCNICA MINIMAMENTE INVASIVA: RELATO DE CASO." Revista Medica Vozandes 31, no. 2 (January 6, 2021): 96–100. http://dx.doi.org/10.48018/rmv.v31.i2.13.
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The maxillary sinus is a pneumatized anatomical structure located bilaterally in the anterior region of the maxilla. The occurrence of displacement of foreign bodies in the maxillary sinus is not a common condition and when present, it is associated with car accidents, fire arm accidents, psychiatric disorders and iatrogenies in surgical procedures. The removal of the foreign body is carried out in order to prevent infections, and the permanence of the foreign body may offer immediate or chronic damage. Access to the maxillary sinus is most commonly performed using the Caldwell-Luc access technique. Thus, the objective of the study is to report a clinical case of surgical removal of a maxillary third molar from the interior of the maxillary sinus using the caldwell-luc access technique, with the aid of a surgical guide in order to conduct a safer and less invasive surgery.
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Kapnick, Senta, Marina Zaitseva, John Scott, Clement Meseda, Henriette Nielsen, Michael Merchlinsky, Jerry Weir, and Hana Golding. "Quantitative bioimaging of WRvFire and of IHDJ-Luc vaccinia virus dissemination in mice and the effects of prophylactic and therapeutic treatments with IgG and antiviral. (45.18)." Journal of Immunology 184, no. 1_Supplement (April 1, 2010): 45.18. http://dx.doi.org/10.4049/jimmunol.184.supp.45.18.
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Abstract Whole body bioluminescence imaging was employed to test the effects of IgG-based therapies and Cidofovir on lethality and virus dissemination in BALB/c mice challenged intranasally with 10^5 pfu of recombinant vaccinia viruses (VV) expressing luciferase, WRvFire or IHDJ-Luc. Both viruses induced lethality within 6-8 days, with slightly different kinetics of replication in internal organs. Using statistical analysis of 80 animals/group we determined that replication of IHDJ-Luc (increased Extracellular Enveloped Virion compared to WR) rose faster and peaked earlier than WRvFire (predominantly Intracellular Mature Virion) in the liver and spleen. In the nasal cavity, WRvFire persisted at significantly higher levels than IHDJ-Luc. Vaccinia immunoglobulin for intravenous injection (VIGIV) administered at day -2 protected 100% of animals from WRvFire and IHDJ-Luc infections. Sym002 (26 anti-vaccinia human mAbs) completely protected mice from both challenges at 300-fold lower dose than VIGIV. A single treatment of Cidofovir (100 mg/kg) at day 1, 2, or 3 p.i. fully protected mice from WRvFire challenge. Complete protection conferred by treatments correlated with significant reductions in bioluminescence in nasal cavity or lungs and in both the liver and spleen between days 1-5. Our data demonstrated that despite some differences observed in the kinetics of VV dissemination, infections with these viruses were similarly susceptible to prophylactic and therapeutic treatments.
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Begemann, Diane, Nicolas Johnston, Marissa O’Callaghan, Grace Walton, Valeriya Steffey, and Fallon Noto. "Abstract A040: In vivo imaging of ovarian and non-small cell lung cancer models hosted in the Sprague-Dawley Rag2 null Il2rgamma null SRG rat (OncoRat®)." Cancer Research 83, no. 2_Supplement_2 (January 15, 2023): A040. http://dx.doi.org/10.1158/1538-7445.metastasis22-a040.
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Abstract Human cancer xenografts are a vital tool for understanding tumor biology. While in vivo studies are traditionally done in immunocompromised mice, we have created the SRG OncoRat® that is an excellent host for human xenografts. In vivo luminescent imaging is routinely used in mouse models, and it is particularly useful for studying orthotopic xenografts or metastatic models. In this study, we validated the SRG rat as a model that can effectively be used for in vivo imaging of human cancers. For the current study, we assessed two tumor models. OV81.2-luc is a luciferase positive cell line that was generated from ascites collection from a grade IIIC serous ovarian carcinoma. Tumors were established by inoculating OV81.2-luc cells IP into female SRG rats and female NSG mice, then treated with vehicle or cisplatin for 28 days. Human non-small cell lung cancer line H358-luc is luciferase positive and metastasizes to lung when injected subcutaneously into the hind flank of SRG rats. Tumors were measured thrice weekly with calipers. For both studies, we performed weekly in vivo luciferase imaging using Spectral Instruments AMI-HT. Tumors established rapidly for both OV81.2-luc and H358-luc in both SRG rats and NSG mice, with luciferin positive signal starting one week post inoculation. In OV81.2-luc hosting animals, upon necropsy, tumors were found on multiple abdominal organs including the peritoneum, ovary, mesentery, intestines, kidneys, liver, and body cavity wall. Metastatic events outside the abdominal cavity were not evident in OV81.2-luc hosting animals. In H358-luc tumor bearing rats, a high metastatic tumor burden was found in the lungs. These data confirm that the SRG rat is an excellent host for studying human cancer when compared to commonly used immunodeficient mouse models. Data demonstrate that the SRG rat has a high utility for studies using both in vivo imaging, such as orthotopic tumor implantation, and studies on metastasis. As the most immunodeficient rat commercially available, the SRG rat retains the ability to establish human tumors while possessing size, physiology, and metabolism-based advantages when compared to mice. Citation Format: Diane Begemann, Nicolas Johnston, Marissa O’Callaghan, Grace Walton, Valeriya Steffey, Fallon Noto. In vivo imaging of ovarian and non-small cell lung cancer models hosted in the Sprague-Dawley Rag2 null Il2rgamma null SRG rat (OncoRat®) [abstract]. In: Proceedings of the AACR Special Conference: Cancer Metastasis; 2022 Nov 14-17; Portland, OR. Philadelphia (PA): AACR; Cancer Res 2022;83(2 Suppl_2):Abstract nr A040.
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Costes, B., V. Stalin Raj, B. Michel, G. Fournier, M. Thirion, L. Gillet, J. Mast, F. Lieffrig, M. Bremont, and A. Vanderplasschen. "The Major Portal of Entry of Koi Herpesvirus in Cyprinus carpio Is the Skin." Journal of Virology 83, no. 7 (January 19, 2009): 2819–30. http://dx.doi.org/10.1128/jvi.02305-08.
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ABSTRACT Koi herpesvirus (KHV), recently designated Cyprinid herpesvirus 3, is the causative agent of a lethal disease in koi and common carp. In the present study, we investigated the portal of entry of KHV in carp by using bioluminescence imaging. Taking advantage of the recent cloning of the KHV genome as a bacterial artificial chromosome (BAC), we produced a recombinant plasmid encoding a firefly luciferase (LUC) expression cassette inserted in the intergenic region between open reading frame (ORF) 136 and ORF 137. Two viral strains were then reconstituted from the modified plasmid, the FL BAC 136 LUC excised strain and the FL BAC 136 LUC TK revertant strain, including a disrupted and a wild-type thymidine kinase (TK) locus, respectively. In vitro, the two recombinant strains replicated comparably to the parental FL strain. The FL BAC 136 LUC TK revertant strain was shown in vitro to induce a bioluminescent signal allowing the detection of single positive cells as early as 24 h postinfection, while in vivo, it induced KHV infection in carp that was indistinguishable from that induced by the parental FL strain. To identify the KHV portal of entry, carp were analyzed by bioluminescence imaging at different times postinfection with the FL BAC 136 LUC TK revertant strain. These analyses demonstrated that the skin of the fish covering the fins and also the body is the major portal of entry for KHV in carp. Finally, to further demonstrate the role of the skin as the KHV portal of entry, we constructed an original system, nicknamed “U-tube,” to perform percutaneous infection restricted to the posterior part of the fish. All the data obtained in the present study demonstrate that the skin, and not the gills, is the major portal of entry for KHV in carp.
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Morrey, Douglas. "Open Wounds: Body and Image in Jean-Luc Nancy and Claire Denis." Film-Philosophy 12, no. 1 (February 2008): 10–30. http://dx.doi.org/10.3366/film.2008.0003.
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Begemann, Diane, and Fallon Noto. "Abstract 2464: In vivo imaging of ovarian and non-small cell lung cancer models hosted in the Sprague-Dawley Rag2 -/-Il2rg -/- SRG rat." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2464. http://dx.doi.org/10.1158/1538-7445.am2022-2464.
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Abstract Human cancer xenografts are a vital tool for understanding tumor biology, growth kinetics, and therapeutic efficacy using animal models. While in vivo studies are traditionally done in immunocompromised mice, we have created a Sprague Dawley Rag2 -/-, Il2rg -/- rat (SRG࣪ OncoRat®) that is an excellent host for human xenografts. Lacking B, T, and NK cells, the SRG rat readily supports the growth of multiple human cancer cell lines, including lines that do not engraft well or grow consistently in existing mouse models. In vivo luminescent imaging has routinely been used in mouse models, and is particularly useful for studying orthotopic xenografts or metastatic models. In this study, we validated the SRG rat as a model that can effectively be used for in vivo imaging of human cancers. For the current study, we assessed two tumor models. Ovarian cancer cell line OV81.2-luc is a luciferase positive cell line that was generated from ascites collection from a grade IIIC, serous ovarian carcinoma. Orthotopic tumors were established by inoculating OV81.2-luc cells intraperitoneally into female SRG rats and female NSG mice, which were treated with either vehicle or cisplatin chemotherapy for 28 days. Human non-small cell lung cancer line H358-luc is a luciferase positive cell line that, when injected subcutaneously into the hind flank of SRG rats, metastasizes to the lungs. Tumors were established by inoculating H358-luc cells subcutaneously into male SRG rats, and measured thrice weekly with calipers. For both studies, tumorgenicity was measured via weekly in vivo luciferase imaging using Spectral Instruments AMI HT system. Tumors established rapidly for both OV81.2-luc and H358-luc in both SRG rats and NSG mice, with visible luciferin positive signal starting one week post cell inoculation. In OV81.2-luc hosting animals, upon necropsy, tumors were found on multiple abdominal organs including the peritoneum, ovary, mesentery, intestines, kidneys, liver, and body cavity wall. Metastatic events outside the abdominal cavity were not evident in OV81.2-luc hosting animals. In H358-luc tumor bearing rats, a high metastatic tumor burden was found in the lungs. These data confirm that the SRG rat is an excellent host for studying human cancer when compared to commonly used immunodeficient mouse models. Data demonstrate that the SRG rat has a high utility for studies using both in vivo imaging, such as orthotopic tumor implantation, and studies on metastasis. As the most immunodeficient rat commercially available, the SRG rat retains the ability to establish human tumors while possessing size, physiology, and metabolism-based advantages when compared to mice. Citation Format: Diane Begemann, Fallon Noto. In vivo imaging of ovarian and non-small cell lung cancer models hosted in the Sprague-Dawley Rag2 -/-Il2rg -/- SRG rat [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2464.
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Fritz, Peter Joseph. "Keeping Sense Open: Jean-Luc Nancy, Karl Rahner, and Bodies." Horizons 43, no. 2 (November 8, 2016): 257–81. http://dx.doi.org/10.1017/hor.2016.62.
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This article introduces the French philosopher Jean-Luc Nancy to theologians by placing him in critical dialogue with Karl Rahner. It examines how Nancy's deconstruction of Christianity accuses Western reason, including Christianity, of forgetting the body and supporting an ethos of disembodiment. Nancy proposes a new opening of reason (déclosion, “dis-closure”) and a corresponding praxis (“adoration”). This reason and praxis involve an exit from Christianity. Rahnerian essays on matter, spirit, and sacramentality demonstrate that while Christianity has, historically, fallen prey to the pathologies Nancy identifies, it also has thought in terms of something like dis-closed reason and has practiced something like “adoration.” While Nancy's insistence on the need for an exit from Christianity is not necessarily well posed, his deconstruction of Christianity can help Christian theologians as they develop thinking that supports an ethos sensitive to the body—or that keeps the body's sense open.
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Nieri, Vitor, Juliana Ferreira de Souza, Talita Cristina Mena Segato, Érika Leão Ajala Caetano, Fernanda Gomes Leite, Marco Vinícius Chaud, and Denise Grotto. "Effects of Green Tea and Green Tea Incorporated in Nanoparticle Lyotropic Liquid Crystal on Exercise Adaptations: A High-Intensity Interval Training Pre-Clinical Study." Nutrients 14, no. 15 (August 7, 2022): 3226. http://dx.doi.org/10.3390/nu14153226.
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Green tea (GT) is a natural antioxidant, sensitive to oxidation after preparation. Lyotropic liquid crystals (LLCs) are nanostructured systems used to incorporate bioactive compounds. High-intensity interval training (HIIT) is a workout modality that increases the production of reactive oxygen species (ROS). Thus, this research aimed to compare the effects of GT and GT loaded in LLC in animals subjected to HIIT, considering hematological, biochemical and histological parameters, redox status, and body mass. Monoolein, GT in infusion and Poloxamer 407 were mixed to obtain nanoparticles of LLC (NP-LLC). Healthy male rats were randomized into six groups (n = 6/group): Control (C), GT, GT-NP-LLC, Exercise (Ex), GT+Ex, GT-NP-LLC+Ex. Body weight was significantly lower in all groups subjected to HIIT compared to C. The percentages of body mass reduction were 11.3, 13.0, 10.0 and 11.0% for Ex, GT+Ex, GT-NP-LLC and GT-NP-LLC+Ex, respectively, compared to control. GT-NP-LLC and Ex reduced triglycerides compared to C. GT and GT-NP-LLC supplementation combined with HIIT presented higher muscle hypertrophy (25 and 21%, respectively), better physical conditioning, and reduced body weight gain rate compared to HIIT by itself. Moreover, the effects of GT-NP-LLC itself on body mass and biochemical parameters are promising, suggesting NP-LLC could improve the bioavailability of GT.
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Bueno, Otto, Miguel San-Miguel, and Edison da Silva. "Ethanol Oxidation on Gold Nanowire Containing Oxygen Impurities: A Study by Ab Initio Molecular Dynamics Simulations." Catalysis Research 02, no. 04 (December 14, 2022): 1–13. http://dx.doi.org/10.21926/cr.2204043.
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Linear atomic chain (LAC) gold nanowires (Au-NWs) containing oxygen impurities are materials that could be used as supports to stimulate chemical reactions. Its peculiar structural characteristics, such as abnormal Au-Au bonds, make it interesting to explore the chemical reactions of this material at a theoretical level. This work investigated the chemical reaction of ethanol supported on Au-NW containing two oxygen impurities. Using <em>ab initio</em> molecular dynamics simulations, it was shown that the presence of oxygen impurity in the LAC conditions the minimum energy paths (MEP) that ethanol will follow in its chemical transformation. When the structure of the LAC contains two oxygen impurities, the formation of acetaldehyde and acetic acid as reaction products were observed. Specifically, the presence of two oxygen impurities in the LAC favors the migration of hydrogens of the -CH<sub>2</sub>- and -OH groups of ethanol towards the LAC. In addition, it was observed that the formation of the C-O bond was favored, which implies an additional reaction intermediate that leads to a total of two different reaction paths in ethanol oxidation.
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Mejía-Escobar, Juan Camilo, Juan David González-Ruiz, and Giovanni Franco-Sepúlveda. "Current State and Development of Green Bonds Market in the Latin America and the Caribbean." Sustainability 13, no. 19 (September 30, 2021): 10872. http://dx.doi.org/10.3390/su131910872.
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The green bonds market has had a growth in recent years within its different sectors and regions. Specifically, up to 2020, the Latin America and the Caribbean (LAC) region has issued USD 26 billion. Some authors have studied the factors influencing financing through green bonds. However, a research gap is identified in the analysis of the regions that contribute to the issuance of this type of bond, specifically for LAC. This is the first study to examine the variables such as issue amount, number and type of issuers, currency, and maturity data in the region using a dataset of issuing performed between 2014–2020. We find the typical sizes of the issues, the search for a premium in the issue, the perception of complexity, the issuance of guides, and tax incentives as the main factors affecting this market. Finally, the study presents the potential for further research.
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TUNBRIDGE, LAURA. "Scarlett Johansson's Body and the Materialization of Voice." Twentieth-Century Music 13, no. 1 (March 2016): 139–52. http://dx.doi.org/10.1017/s1478572215000201.
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AbstractThis article considers three science fiction films, released in 2013–14, featuring Scarlett Johansson:Her(dir. Spike Jonze),Lucy(dir. Luc Besson), andUnder the Skin(dir. Jonathan Glazer). It suggests that to engage with the phenomenon of voice in imaginative and productive ways it is necessary to slide over a disciplinary divide and address more explicitly the musicality of speech. In my main example,Her, Johansson provides the voice of an operating system with which the film's protagonist falls in love. Central to their intimate connection is the establishment of what I call the ‘haptic voice’, which conveys a sense of physical proximity. A similar blurring of the boundaries between voice and body occur in the presentation of the alien characters Johansson plays in the other films.
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Hernando, Diego, Ruiyang Zhao, Qing Yuan, Mounes Aliyari Ghasabeh, Stefan Ruschke, Xinran Miao, Dimitrios C. Karampinos, et al. "Multi-Center, Multi-Vendor Reproducibility and Calibration of MRI-Based R2* for Liver Iron Quantification." Blood 138, Supplement 1 (November 5, 2021): 2010. http://dx.doi.org/10.1182/blood-2021-148803.
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Abstract Introduction: Excessive accumulation of iron is caused by a variety of conditions, including hereditary hemochromatosis and transfusional hemosiderosis. If untreated, iron overload can lead to damage in those organs where iron accumulates. Therefore, accurate and reproducible evaluation of body iron stores is needed to guide diagnosis, grading, and treatment monitoring of iron overload. While serum ferritin is the simplest means to assess body iron, it is also an acute phase reactant and therefore is not a reliable biomarker of body iron. Liver iron concentration (LIC) is directly and linearly related to total body iron stores. As such, LIC is widely recognized as a useful surrogate biomarker for the evaluation of iron overload. Liver biopsy is limited by its invasive nature and is contraindicated in many patients (eg. thrombocytopenia) due to bleeding risk. Magnetic resonance imaging (MRI) is a standard of care tool to measure LIC. Arguably the most practical method is R2* MRI due to its speed and ease of use, but the cross-vendor reproducibility of R2*-based LIC estimation remains unknown. Therefore, we evaluated the reproducibility and calibration of R2*-based LIC measurement via a single-breath-hold, confounder-corrected R2*-MRI at both 1.5T and 3T, through a multi-center, multi-vendor study. Methods: Four centers (University of Wisconsin-Madison, University of Texas-Southwestern, Johns Hopkins University, and Stanford University) using MRI scanners of different vendors (GE, Philips, and Siemens) participated in this HIPAA-compliant IRB-approved prospective cross-sectional study. This study recruited subjects with known or suspected iron overload from a variety of etiologies, including hereditary hemochromatosis, transfusional hemosiderosis (due to non-malignant or malignant conditions), and chronic liver disease. Subjects with were recruited for same day multiecho gradient-echo MRI for R2* mapping at both 1.5T and 3T (UW, UTSW, Stanford: 3.0T; JHU: 2.89T). R2* maps were reconstructed from the raw multiecho images and analyzed at a single center. Spin-echo MRI were also performed at 1.5T according to a standardized protocol (FerriScan, Resonance Health, Australia) and processed by a commercial algorithm to obtain FDA-approved reference standard LIC estimates. R2*-vs.-LIC calibrations were generated across centers and field strengths using linear regression and compared using F-tests. A predicted 2.89T calibration was interpolated from the 1.5T and 3.0T calibrations, and compared to the measured (JHU) calibration. Receiver operating characteristic (ROC) curve analysis was performed to determine the diagnostic accuracy of R2* MRI for detection of clinically relevant LIC thresholds. Results: A total of 200 subjects were recruited and successfully scanned for this study. We confirmed a linear relationship between R2* and LIC. All calibrations within the same field strength (see Figure 1) were highly reproducible showing no statistically significant center-specific differences (F > 3.0461). Pooled calibrations for 1.5T, 2.89T, and 3.0T were generated. At either field strength and for each of the LIC thresholds under consideration (1.8, 3.2, 7.0, 15.0 mg/g), estimated areas under the ROC curve (AUCs) of 0.98 or higher were observed. Discussion and Conclusions: In conclusion, confounder-corrected R2* MRI enables accurate and reproducible quantification of liver iron overload, over clinically relevant ranges of LIC. The data generated in this study provide the necessary calibrations for broad dissemination of R2*-based LIC quantification. Figure 1 Figure 1. Disclosures Hernando: Calimetrix: Current holder of individual stocks in a privately-held company. Pedrosa: Merck: Honoraria; Bayer Healthcare: Honoraria; Health Tech International: Current holder of stock options in a privately-held company. Vasanawala: HeartVista: Current holder of individual stocks in a privately-held company; InkSpace: Current holder of individual stocks in a privately-held company; Arterys: Current holder of individual stocks in a privately-held company. Reeder: Bayer: Research Funding; Pfizer: Research Funding; Calimetrix, LLC: Current holder of individual stocks in a privately-held company; Reveal Pharmaceuticals: Current holder of individual stocks in a privately-held company; Elucent Medical: Current holder of individual stocks in a privately-held company; Cellectar Biosciences: Current holder of individual stocks in a privately-held company; HeartVista: Current holder of individual stocks in a privately-held company.
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Maillo Palma, Laura. "Nauman, Mirecka, Rainer: entre el cuerpo y el gesto / Nauman, Mirecka, Rainer: between body and sign." Laocoonte. Revista de Estética y Teoría de las Artes, no. 4 (December 12, 2017): 134. http://dx.doi.org/10.7203/laocoonte.0.4.10280.
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¿Existe un lenguaje físico, que subsuma al lenguaje verbal? Para plantear esta pregunta, en toda su amplitud, primero, nos detendremos en la observación del cuerpo como objeto y sujeto artístico a partir de tres piezas realizadas por el performer Bruce Nauman, la actriz Rena Mirecka y la bailarina Yvonne Rainer, respectivamente. En lo que sigue, continuaremos adentrándonos en el territorio de lo corpóreo ?ya explorado pero aún inexorable— con la ayuda de Jean-Luc Nancy. Y, finalmente, buscaremos conexiones con el territorio del signo, estudiado por Umberto Eco y por Erika Fischer-Lichte, en su caso, en directa aplicación al campo de la realización escénica.Is there a physical language that subsumes the verbal language? To bring this question up, in all its amplitude, firstly, we will detain in the observation of the body as an artistic object and subject after three pieces carried out by the performer Bruce Nauman, the actress Rena Mirecka and the dancer Yvonne Rainer, respectively. As of what follows, we will continue to get into the territory of the body ?already explored yet still inexorable? with help of Jean-Luc Nancy. And finally, we will search for connections with the territory of the sign, studied by Umberto Eco and Erika Fischer-Lichte, in whose case, in direct application to the performance fields.
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Vrînceanu, Daniela, M. Dumitru, B. Banica, and Adriana Nica. "FOREIGN BODY IN MAXILLARY SINUS WITH SKIN FISTULA – CLINICAL CASE." Journal of Surgical Sciences 6, no. 3 (November 6, 2019): 82–84. http://dx.doi.org/10.33695/jss.v6i3.278.
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We present the case of a 41 years old patient with poor social status and previous facial trauma with a sharp object (wood branch) 2 years ago. Although it was performed the extraction of the branch in a local ENT department, the patient developed a fistula in the left genian region with the presence of puss. Two months ago the patient undergoes another head trauma leading to neurosurgery. CT scan raises the suspicion of a foreign body in the left maxillary sinus. We performed left maxillary sinus surgery through Caldwell-Luc approach with extraction of the foreign body and closure of the fistula. Surgical healing was optimal within 10 days. We analyze the medico-legal implications of such cases.
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Dixon, P., and D. Mannion. "Goldsmith and the Busy Body." Literary and Linguistic Computing 22, no. 4 (September 21, 2007): 435–46. http://dx.doi.org/10.1093/llc/fqm028.
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Guo, Yihang, Honghong Wang, Jeni L. Gerberich, Samuel O. Odutola, Amanda K. Charlton-Sevcik, Maoping Li, Rajendra P. Tanpure, et al. "Imaging-Guided Evaluation of the Novel Small-Molecule Benzosuberene Tubulin-Binding Agent KGP265 as a Potential Therapeutic Agent for Cancer Treatment." Cancers 13, no. 19 (September 24, 2021): 4769. http://dx.doi.org/10.3390/cancers13194769.
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The selective disruption of tumor-associated vasculature represents an attractive therapeutic approach. We have undertaken the first in vivo evaluation of KGP265, a water-soluble prodrug of a benzosuberene-based tubulin-binding agent, and found promising vascular-disrupting activity in three distinct tumor types. Dose escalation in orthotopic MDA-MB-231-luc breast tumor xenografts in mice indicated that higher doses produced more effective vascular shutdown, as revealed by dynamic bioluminescence imaging (BLI). In syngeneic orthotopic 4T1-luc breast and RENCA-luc kidney tumors, dynamic BLI and oxygen enhanced multispectral optoacoustic tomography (OE-MSOT) were used to compare vascular shutdown following the administration of KGP265 (7.5 mg/kg). The BLI signal and vascular oxygenation response (ΔsO2) to a gas breathing challenge were both significantly reduced within 2 h, indicating vascular disruption, which continued over 24 h. A correlative histology confirmed increased necrosis and hemorrhage. Twice-weekly doses of KGP265 caused significant growth delay in both MDA-MB-231 and 4T1 breast tumors, with no obvious systemic toxicity. A combination with carboplatin produced significantly greater tumor growth delay than carboplatin alone, though significant carboplatin-associated toxicity was observed (whole-body weight loss). KGP265 was found to be effective at low concentrations, generating long-term vascular shutdown and tumor growth delay, thus providing strong rationale for further development, particularly in combination therapies.
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Šlapkauskaitė, Rūta. "“Like being trapped in a drum”: The Poetics of Resonance in Frances Itani’s Deafening." Anglica. An International Journal of English Studies, no. 27/3 (September 17, 2018): 201–32. http://dx.doi.org/10.7311/0860-5734.27.3.10.
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This paper considers how Frances Itani’s Deafening imaginatively rethinks our understanding of the Great War in the age of postmemory. Seeing as the novel is set in Canada and Europe during the First World War and takes as its protagonist a deaf woman, the poetic attention given to the senses as a horizon of phenomenological experience magnifies the moral bonds that the characters establish in defi ance of both deafness and death. Guided by the theoretical reasoning of Marianne Hirsch, Elaine Scarry, and Alison Landsberg as well as contemporary phenomenological thinking, most significantly that of Edward S. Casey, Steven Connor, Michel Serres, and Jean-Luc Nancy, this paper examines how the novel’s attentiveness to the materiality of the body in regard to the ethical collisions of sound and silence as well as life and death contributes to a poetics of resonance that generates prosthetic memories, turning the anonymous record of war into a private experience of moral endurance inscribed on the ear of historical legacy.
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Kan, Yu Cheng, Kuang Chih Pei, and Wei Lin Hsu. "Bond Behavior of Low-Activated High Aluminate Concrete with Reinforcement under Cyclic Load." Materials Science Forum 972 (October 2019): 34–39. http://dx.doi.org/10.4028/www.scientific.net/msf.972.34.
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The bond behavior of reinforcement and low-activated concrete (LAC) was investigated in this study. The acoustic emission monitoring was also engaged while the specimen being loaded to figure out the inside fracture. Static loading and dynamic loading were applied for both of the LAC and normal concrete in the pull-out tests. The upper load was applied starting from 30% of the static ultimate load Pu with a 10% increment until the failure. The loading frequencies for the test were 0.5 Hz、1.0 Hz and 2.0 Hz. The bond stiffness after each stage of dynamical loads was examined. Test results reveal that the LAC performs higher compressive strength than normal concrete for a given W/C ratio. But, the bond strength of LAC seems not promotes correspondingly. It may be attributed to the conversion effect of high alumina contained in LAC, which leads to more voids inside the concrete.
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Sepúlveda, Ana Rosa, Tatiana Lacruz, Santos Solano, Miriam Blanco, Alba Moreno, Marta Rojo, Lucía Beltrán, and Montserrat Graell. "Identifying Loss of Control Eating within Childhood Obesity: The Importance of Family Environment and Child Psychological Distress." Children 7, no. 11 (November 11, 2020): 225. http://dx.doi.org/10.3390/children7110225.
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This study aims to examine the differences in family environment, psychological distress, and disordered eating symptomatology between children classified by weight status with or without loss of control (LOC) eating and to test a model of the role of emotional regulation of LOC eating based on a dysfunctional family environment. A cross-sectional study was conducted among 239 families. The assessment measured family expressed emotion, family adaptability and cohesion, child levels of depression and anxiety, body esteem, and disordered eating attitudes. The assessment was carried out in primary care centers and primary schools. Child body mass index (BMI) was associated with higher expressed emotion, psychological distress, and disordered eating symptomatology. Children with obesity and LOC presented higher BMI, poorer body esteem, and more disordered eating attitudes than children without LOC. Children with overweight/obesity, both with or without LOC, exhibited higher psychological distress and emotional overinvolvement than normal-weight children. A partial mediation of depression or anxiety and disordered eating attitudes between expressed emotion and LOC was found. Findings support that children with overweight/obesity show more family and psychological distress. Body esteem issues and disordered eating attitudes could alert the presence of LOC in children with obesity. The function of LOC might be to cope with psychological distress that may appear in a dysfunctional family environment.
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Jakešová, Markéta. "Mass of Bodies, Body as a Mass: The Other of the Other in Jean-Luc Nancy." Research in Phenomenology 50, no. 1 (May 7, 2020): 17–30. http://dx.doi.org/10.1163/15691640-12341437.
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Abstract This paper aims to explore and expand Jean-Luc Nancy’s notion of the body as a mass as he drafted it in his “On the Soul” lecture. He conceptualizes the soul as the (however minimal) reflection of the fact that we have (or we are) a body, thus the conception of the body as a mass may offer possibilities to think the body outside or prior to this reflection. In the article, I expand on three types of bodies. The first of these possibilities is an abstracted body Nancy ascribed to St. Augustine, a body which has been criticized by feminist scholars like Judith Butler. The second one is a hypothetical pre-body proposed by the object-oriented philosopher Graham Harman that may have existed before the actual body emerges. The last one is the disintegrated rotting body in two different contexts: European baroque imagery and asubha kammaṭṭhāna, a Thai meditational practice. All three types of bodies-as-a-mass are legitimate conceptualizations of what Nancy indicates. However, the mass quality is the very nonconceptuality, which is therefore the ultimate outcome that I had to reach.
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Zhou, Xue-Fei. "Oxidation of Lignin-Carbohydrate Complex by Laccase/Co(salen) One-Pot Catalysis." Sains Malaysiana 51, no. 3 (March 31, 2022): 723–32. http://dx.doi.org/10.17576/jsm-2022-5103-07.
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Lignin-carbohydrate complex (LCC) is hybrid structures containing covalently linked moieties of lignin and carbohydrates. The nature and amount of LCC affect both industrial processes and practical applications of lignocellulosic biomass. Herein, the LCC was isolated from bamboo by successive solvent extraction and precipitation. The effects and mechanism of LCC oxidation respectively by laccase, Co(salen), and laccase/Co(salen) in the presence of molecular oxygen have been investigated by composition analysis using the standard of National Renewable Energy Laboratory (NREL) and high-performance anion exchange chromatography (HPAEC), GPC, FTIR, and 2D-HSQC NMR. We can conclude that the laccase/Co(salen) one-pot catalysis modified the LCC in such a way that more carbohydrate was removed from the LCC with lower molecular weight of LCC as shown by GPC; the catalytic treatments produced oxidation at lignin side-chains and cleavage of lignin β-O-4', β-β' and β-5' bonds in LCC, and cleavage of benzyl-sugar ether, phenyl glycoside and γ-ester bonds in LCC, as shown by FTIR and 2D-HSQC NMR, especially after the laccase/Co(salen) one-pot treatment. The further insight of LCC degradation was discussed in light of the results obtained in oxidation of the LCC model compound coniferin.
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Karpowicz, Jolanta, Patryk Zradziński, Jarosław Kieliszek, Krzysztof Gryz, Jaromir Sobiech, and Wiesław Leszko. "An In Situ and In Silico Evaluation of Biophysical Effects of 27 MHz Electromagnetic Whole Body Humans Exposure Expressed by the Limb Current." BioMed Research International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/5785482.
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Objectives. The aim was to evaluate correlations between biophysical effects of 27 MHz electromagnetic field exposure in humans (limb induced current (LIC)) and (1) parameters of affecting heterogeneous electric field and (2) body anthropometric properties, in order to improve the evaluation of electromagnetic environmental hazards. Methods. Biophysical effects of exposure were studied in situ by measurements of LIC in 24 volunteers (at the ankle) standing near radio communication rod antenna and in silico in 4 numerical body phantoms exposed near a model of antenna. Results. Strong, positive, statistically significant correlations were found in all exposure scenarios between LIC and body volume index (body height multiplied by mass) (r>0.7; p<0.001). The most informative exposure parameters, with respect to the evaluation of electromagnetic hazards by measurements (i.e., the ones strongest correlated with LIC), were found to be the value of electric field (unperturbed field, in the absence of body) in front of the chest (50 cm from body axis) or the maximum value in space occupied by human. Such parameters were not analysed in previous studies. Conclusions. Exposed person’s body volume and electric field strength in front of the chest determine LIC in studied exposure scenarios, but their wider applicability needs further studies.
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Choi, Seulah. "Body as an Finite Existence in Writing and Love: Reading Jean-Luc Nancy’s Corpus." Mihak - The Korean Journal of Aesthetics 86, no. 4 (December 30, 2020): 109–35. http://dx.doi.org/10.52720/mihak.86.4.4.
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Twomey, Jay. "Review of Jean-Luc Nancy,Noli me tangere: On the Raising of the Body." Bible and Critical Theory 6, no. 3 (October 2010): 52.1–52.3. http://dx.doi.org/10.2104/bc100052.
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Lieberman, Stuart. "Book Reviews: The Psyche and Schizophrenia: the Bond Between Affect and Logic Luc Ciompi." International Journal of Social Psychiatry 35, no. 3 (September 1989): 289. http://dx.doi.org/10.1177/002076408903500314.
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Pallesen, Carsten. "Homoousia – sprog, krop, trinitet i mediefilosofisk perspektiv." Dansk Teologisk Tidsskrift 79, no. 2 (May 10, 2016): 82–104. http://dx.doi.org/10.7146/dtt.v79i2.105781.
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From the vantage point of body and language in contemporary philosophy of media the article suggests a reinterpretation of the key term homoousia of the Nicene Creed. The concept of homoousia serves as a guideline for Martin Luther’s understanding of the trinity in dialogical rather than narrative terms. The article explores the hermeneutical dimension of body metaphors and language in the Trinitarian faith in a trajectory of reception from Luther to Post-Hegelian theories from Hans-Georg Gadamer to Niklas Luhman, Jean-Luc Nancy and Giorgio Agamben and in contemporary theological interpretations by Carl Andresen, Günter Bader, Eberhard Jüngel and Phillipp Stoellger.
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McMahon, Laura. "Beyond the human body: Claire Denis's ecologies." Alphaville: Journal of Film and Screen Media, no. 7 (June 25, 2014): 94–111. http://dx.doi.org/10.33178/alpha.7.06.
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This article explores the work of Claire Denis beyond the focus on the human body through which it is commonly read. Addressing Beau Travail (1999) and The Intruder (2004), I examine an ecological impulse that manifests itself through a nonanthropocentric detailing of the coexistence of body and landscape, and a nonhierarchical attentiveness to the distributed agencies of humans, animals and things. I draw here in particular on Gilles Deleuze’s notion of the crystal-image and on Jean-Luc Nancy’s thinking of ecotechnics, as elaborated in his essay on The Intruder (a film inspired by Nancy’s autobiographical essay, L’Intrus). In Beau Travail, Deleuzian crystals of time draw attention to the nonhuman histories of the landscape. In The Intruder, this crystalline structure persists, reactivating traces of nonhuman pasts, while a focus on canine gestures and responses signals nonhuman perceptual worlds in the present. Deleuze’s “Desert Islands”, another text that shapes The Intruder, offers a further way of reading the film’s attentiveness to the nonhuman—an attentiveness that extends, as Nancy suggests, to a consideration of environmental crisis.
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Tsuda, Hiroyuki, Tomomi Kotani, Seiji Sumigama, Ichiro Kawabata, Yuichiro Takahashi, Shigenori Iwagaki, Kaori Kigoshi, and Fumitaka Kikkawa. "Validity of Lamellar Body Count as a Fetal Lung Maturity Assessment in Twin Pregnancy." Twin Research and Human Genetics 15, no. 4 (July 5, 2012): 547–49. http://dx.doi.org/10.1017/thg.2012.29.
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Fetal lung maturity assessment in twin pregnancy has been discussed, but is still controversial. The purpose of this study is to predict the occurrence of respiratory distress syndrome (RDS) using lamellar body count (LBC) and analyze the validity of LBC for fetal lung maturity assessment in twin pregnancy. Three-hundred two amniotic fluid samples were obtained at cesarean section from 29 to 38 weeks of gestation. Samples were analyzed immediately with no centrifugation and the number of lamellar bodies was counted using a platelet channel on the Sysmex SF-3000. There were 18 neonates (6.0%) suffering from RDS. An LBC cut-off value of 2.95 × 104/μL resulted in 91.5% sensitivity and 83.3% specificity for predicting RDS. This cut-off value for predicting RDS was the same as that in singleton pregnancy. Moreover, the median LBC value in RDS cases was significantly lower than in non-RDS cases (1.50 ± 1.1 × 104/μL vs. 10.6 ± 7.5 × 104/μL; p < .001). This is the first report on the validity of LBC in twin pregnancy and also the largest study on fetal lung maturity assessment in twin pregnancy. An LBC value of >2.95 × 104/μL means reassuring findings for RDS even in twin pregnancy. We believe the data in this study provide valuable, new information for the management of twin pregnancies.