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Relevant bibliographies by topics / Lumefantrina

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Journal articles
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Book chapters
Conference papers

Academic literature on the topic 'Lumefantrina'

Author: Grafiati

Published: 9 September 2021

Last updated: 29 July 2025

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Journal articles on the topic "Lumefantrina"

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Gonçalves, Bruna Vaz da Silva, Isis Regina Barberini, and Silvana Krychak Furtado. "Panorama global acerca da eficácia de medicamentos antimaláricos para o tratamento de p. falciparum e p. vivax no período de 2010 a 2018." Scire Salutis 12, no. 2 (2022): 10–18. http://dx.doi.org/10.6008/cbpc2236-9600.2022.002.0002.

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Há um amplo consenso de que proteger a eficácia dos medicamentos antimaláricos é uma prioridade de saúde global. O trabalho foi desenvolvido por meio do levantamento de um total de 925 estudos de eficácia terapêutica conduzidos e documentados pela OMS acerca da eficácia de antimaláricos aplicados às espécies de plasmódio supracitados entre o período de 2010 a 2018. O número de estudos sobre a eficácia terapêutica para antimaláricos aplicados para P. falciparum resultam em artemeter-lumefantrina que inclui 317 estudos realizados em 50 países. Artesunato-amodiaquina incluiu 122 estudos em 26 paí

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Freitas-Marques, Maria Betânia de, Wagner da Nova Mussel1, Maria Irene Yoshida, Christian Fernandes, Tércio Assunção Pedros, and Pedro Henrique Reis da Silva. "Interações químicas entre monômero e molécula molde em polímeros com impressão molecular, o EGDMA: 2-VP (4: 1) - estudo de caso MIP lumefantrina." Journal of Experimental Techniques and Instrumentation 4, no. 04 (2021): 56–76. http://dx.doi.org/10.30609/jeti.v4i04.14486.

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Molecularly Imprinted Polymers (MIP) are synthetic materials used as a tool to enhance the selectivity in different analytical approaches, such as solid-phase extraction, chromatography, and sensing devices. Knowing the mechanism involved in the interaction between the template and monomer is essential for a further successful application. However, studies on this topic are scarce. This work evaluates the involved mechanisms in the template-monomer interaction for a lumefantrine MIP system, an antimalarial drug. Field-emission gun scanning electron microscopy, thermal analysis, X-ray diffracti

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Lima, Agostinho Viana, and Fernando Mitano. "Saberes sobre a malária: um estudo qualitativo baseado no Distrito do Lago, Província de Niassa (Moçambique – África)." VITTALLE - Revista de Ciências da Saúde 32, no. 3 (2020): 107–18. http://dx.doi.org/10.14295/vittalle.v32i3.11819.

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Procurou-se compreender o modo como a população do Distrito do Lago (Província de Niassa, Moçambique) percebe, previne e trata a malária. Trata-se de um estudo de cunho qualitativo, centrado na abordagem de modelos explicativos da doença, que contou com a participação de membros de agregados familiares, profissionais de saúde e médicos tradicionais. A coleta de dados aconteceu por meio de entrevistas, orientadas por um roteiro semiestruturado, realizadas nos meses de Setembro e Novembro de 2019 em 8 povoados do Distrito do Lago. Os resultados revelaram um entendimento de que a malária é uma do

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Carmona-Fonseca, Jaime, Olga María Agudelo-García, and Eliana Arango-Flórez. "Eficacia terapéutica y eventos adversos de tratamientos para malaria vivax y malaria falciparum en gestantes en las regiones de Urabá y Alto San Jorge, Colombia, 2008-2011." Revista Colombiana de Obstetricia y Ginecología 64, no. 1 (2013): 27–37. http://dx.doi.org/10.18597/rcog.127.

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Objetivo: evaluar, con el protocolo de la Organización Mundial de la Salud (OMS) de 1998, la respuesta terapéutica antimalárica (RTA) y los eventos adversos (EA) en cuatro esquemas de tratamiento antiplasmodial en gestantes colombianas, con diagnóstico de malaria no complicada por P. vivax o por P. falciparum, según gota gruesa.Materiales y métodos: experimento controlado aleatorizado en paralelo. Se calculó un tamaño muestral de 60 pacientes con P. vivax y 30 con P. falciparum. Se evaluaron cuatro tratamientos: malaria vivax en cualquier trimestre de gestación tratada con cloroquina o con amo

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Cortés Jiménez, Lady Tatiana, Camilo Andrés Rivera Perdomo, Duván Felipe Velandia, Lorena García Agudelo, and Ledmar Jovanny Vargas Rodríguez. "Malaria autóctona: caso clínico." Revista Med 32, no. 1 (2024): 101–6. http://dx.doi.org/10.18359/rmed.7183.

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Introducción: La malaria o paludismo es una infección parasitaria frecuente en las regiones tropicales del mundo, donde anualmente se infectan entre 300 y 500 millones de personas, siendo responsable de 1,5 a 2,7 millones de muertes al año. Hoy en día es considerada un problema de salud pública grave por las condiciones que facilitan la reproducción y transmisión del parásito Plasmodium. Objetivo: El objetivo del manuscrito es presentar el caso de un paciente con malaria autóctona. Caso clínico: Paciente femenina de 33 años, quien consultó por cuadro clínico de doce días de evolución consisten

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Kloprogge, Frank, Rose McGready, Warunee Hanpithakpong, et al. "Lumefantrine and Desbutyl-Lumefantrine Population Pharmacokinetic-Pharmacodynamic Relationships in Pregnant Women with Uncomplicated Plasmodium falciparum Malaria on the Thailand-Myanmar Border." Antimicrobial Agents and Chemotherapy 59, no. 10 (2015): 6375–84. http://dx.doi.org/10.1128/aac.00267-15.

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ABSTRACTArtemether-lumefantrine is the most widely used antimalarial artemisinin-based combination treatment. Recent studies have suggested that day 7 plasma concentrations of the potent metabolite desbutyl-lumefantrine correlate better with treatment outcomes than those of lumefantrine. Low cure rates have been reported in pregnant women with uncomplicated falciparum malaria treated with artemether-lumefantrine in northwest Thailand. A simultaneous pharmacokinetic drug-metabolite model was developed based on dense venous and sparse capillary lumefantrine and desbutyl-lumefantrine plasma sampl

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Wahajuddin, Kanumuri S. R. Raju, Sheelendra P. Singh, and Isha Taneja. "Investigation of the Functional Role of P-Glycoprotein in Limiting the Oral Bioavailability of Lumefantrine." Antimicrobial Agents and Chemotherapy 58, no. 1 (2013): 489–94. http://dx.doi.org/10.1128/aac.01382-13.

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ABSTRACTIn the quest to explore the reason for the low and variable bioavailability of lumefantrine, we investigated the possible role of P-glycoprotein (P-gp) in lumefantrine intestinal absorption. Anin situsingle-pass intestinal perfusion study in rats with the P-gp inhibitor verapamil or quinidine and an ATPase assay with human P-gp membranes indicated that lumefantrine is a substrate of P-gp which limits its intestinal absorption. To confirm these findings, anin vivopharmacokinetic study was performed in rats. The oral administration of verapamil (10 mg/kg of body weight) along with lumefa

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Salman, Sam, Madhu Page-Sharp, Susan Griffin, et al. "Population Pharmacokinetics of Artemether, Lumefantrine, and Their Respective Metabolites in Papua New Guinean Children with Uncomplicated Malaria." Antimicrobial Agents and Chemotherapy 55, no. 11 (2011): 5306–13. http://dx.doi.org/10.1128/aac.05136-11.

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ABSTRACTThere are sparse published data relating to the pharmacokinetic properties of artemether, lumefantrine, and their active metabolites in children, especially desbutyl-lumefantrine. We studied 13 Papua New Guinean children aged 5 to 10 years with uncomplicated malaria who received the six recommended doses of artemether (1.7 mg/kg of body weight) plus lumefantrine (10 mg/kg), given with fat over 3 days. Intensive blood sampling was carried out over 42 days. Plasma artemether, dihydroartemisinin, lumefantrine, and desbutyl-lumefantrine were assayed using liquid chromatography-mass spectro

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Parikh, Sunil, Fatai Fehintola, Liusheng Huang, et al. "Artemether-Lumefantrine Exposure in HIV-Infected Nigerian Subjects on Nevirapine-Containing Antiretroviral Therapy." Antimicrobial Agents and Chemotherapy 59, no. 12 (2015): 7852–56. http://dx.doi.org/10.1128/aac.01153-15.

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ABSTRACTCoadministration of nevirapine-based antiretroviral therapy (ART) and artemether-lumefantrine is reported to result in variable changes in lumefantrine exposure. We conducted an intensive pharmacokinetic study with 11 HIV-infected adults who were receiving artemether-lumefantrine plus nevirapine-based ART, and we compared the results with those for 16 HIV-negative adult historical controls. Exposure to artemether and lumefantrine was significantly lower and dihydroartemisinin exposure was unchanged in subjects receiving nevirapine-based ART, compared with controls. Nevirapine exposure

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Abolaji, AO, OA Adesanoye, I. Awogbindin, and EO Farombi. "Endocrine disruption and oxidative stress implications of artemether–lumefantrine combination therapy in the ovary and uterus of rats." Human & Experimental Toxicology 35, no. 11 (2016): 1173–82. http://dx.doi.org/10.1177/0960327115626580.

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In the current study, we evaluated the endocrine disruption effect and oxidative stress implication of therapeutic dose of artemether–lumefantrine combination therapy on the ovary and uterus of rats. In this respect, female rats were divided into four groups: animals were per orally treated with tween 80 (control), artemether (4 mg kg−1 body weight), lumefantrine (24 mg kg−1 body weight) and artemether–lumefantrine (artemether, 4 mg kg−1 body weight and lumefantrine, 24 mg kg−1 body weight). We found that therapeutic doses of the drugs did not change the levels of ovarian hydrogen peroxide (H2

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Dissertations / Theses on the topic "Lumefantrina"

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Freitas, Lita Lay. "Eficácia da associação de arteméter e lumefantrina no tratamento da malária por Plasmodium falciparum resistente à cloroquina em Timor Leste." Master's thesis, Faculdade de Medicina da Universidade do Porto, 2009. http://hdl.handle.net/10216/53513.

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Cesar, Isabela da Costa. "Desenvolvimento de métodos analíticos para quantificação de artemeter e lumefantrina em comprimidos de dose fixa combinada e em plasma humano." Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/FARD-7ZPEVX.

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Nowadays, malaria is the worlds most incident parasitic infection. The artemisinin based combination therapy (ACT) has been advocated as a promising treatment for malaria and artemetherlumefantrine (20+120 mg) is the main recommended association in endemic areas. In spite of the wide use of this association, the scientific literature is still scarce regarding analytical methods for the quantitation of artemether and lumefantrine in pharmaceutical products and biological matrices. The aim of the present work was developing and validating analytical methods for the quantitation of artemether and

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Freitas, Lita Lay. "Eficácia da associação de arteméter e lumefantrina no tratamento da malária por Plasmodium falciparum resistente à cloroquina em Timor Leste." Dissertação, Faculdade de Medicina da Universidade do Porto, 2009. http://hdl.handle.net/10216/53513.

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Couto, Shirley Claudino Pereira. "Influência do tratamento com os antiplasmodiais artemeter, lumefantrina e mefloquina em funções dos monócitos envolvidas na defesa contra as formas eritrocitárias do Plasmodium falciparum." reponame:Repositório Institucional da UnB, 2015. http://repositorio.unb.br/handle/10482/23164.

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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Pós-graduação em Medicina Tropical, 2015.<br>Submitted by Raquel Viana (raquelviana@bce.unb.br) on 2017-03-03T17:43:05Z No. of bitstreams: 1 2015_ShirleyClaudinoPereiraCouto.pdf: 2005336 bytes, checksum: 109e6489df275decec29166652ec4123 (MD5)<br>Approved for entry into archive by Ruthléa Nascimento(ruthleanascimento@bce.unb.br) on 2017-03-31T16:30:49Z (GMT) No. of bitstreams: 1 2015_ShirleyClaudinoPereiraCouto.pdf: 2005336 bytes, checksum: 109e6489df275decec29166652ec4123 (MD5)<br>Made available in DSpace on 2017-03-31T16:

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PINHEIRO, Priscila de Nazaré Quaresma. "Validação de metodologia analítica para determinação de lumefantrina em plasma e sangue total adsorvido em papel de filtro por cromatografia líquida de alta eficiência (CLAE) em pacientes com malária por plasmodium falciparum." Universidade Federal do Pará, 2010. http://repositorio.ufpa.br/jspui/handle/2011/3899.

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Submitted by Edisangela Bastos (edisangela@ufpa.br) on 2013-05-20T22:18:44Z No. of bitstreams: 2 license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) Dissertacao_ValidacaoMetodologiaAnalitica.pdf: 1357135 bytes, checksum: 0ddefd417c885b4db3c7d39d75f34b15 (MD5)<br>Approved for entry into archive by Ana Rosa Silva(arosa@ufpa.br) on 2013-05-27T12:30:07Z (GMT) No. of bitstreams: 2 license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) Dissertacao_ValidacaoMetodologiaAnalitica.pdf: 1357135 bytes, checksum: 0ddefd417c885b4db3c7d39d75f34b15 (MD5)<br>Made

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Makanga, Michael Musakiriza. "The cellular and molecular basis of co-artemether (artemether-lumefantrine) action." Thesis, University of Liverpool, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269599.

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Jacobs, Suesan, Amanda Vonderfecht, and Georg Wondrak. "Artemisinin-Based Combination Anti-malarials Do Not Enhance Anti-melanoma Activity of Artemisinin-Monotherapy." The University of Arizona, 2013. http://hdl.handle.net/10150/614262.

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Class of 2013 Abstract<br>Specific Aims: To determine if melanoma cells are more vulnerable to Amodiaquine (AQ) or Lumefantrine (LF)-based artemisinin combination therapy compared to artemisinin monotherapy. Methods: Tested anti-malarials in vitro for anti-melanoma activity, which contained 100,000 of the A375 human metastatic melanoma cells that were repeatedly treated independently three times. Main Results: Dihydroartemisinin (DHA) monotherapy induced significant cell death in melanoma cells. However, artemisinin combination therapy (ACT) did not enhance DHA-induced cell death. AQ prot

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Mudyahoto, Tsitsi. "Formulation, characterisation and optimisation of self-nanoemulsifying drug delivery systems (SNEDDS) loaded with artemether and lumefantrine." Thesis, Rhodes University, 2018. http://hdl.handle.net/10962/63503.

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Govender, Katya. "A pharmacokinetic and efficacy study of Lumefantrine in mice: evaluating the application of Pheroid™ technology." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/3393.

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Bruxvoort, K. "Evaluation of patient adherence to artemether-lumefantrine obtained from public and private drug outlets in Tanzania." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2015. http://researchonline.lshtm.ac.uk/2173661/.

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Adherence to artemisinin-based combination therapies (ACTs) for malaria is important for effective treatment. This thesis compares adherence to ACTs obtained in the public and private retail sectors, describes an intervention to improve dispenser knowledge and patient adherence, and addresses challenges of measuring patient adherence to ACTs. A cluster randomised trial of a text message intervention targeted at dispensers in Accredited Drug Dispensing Outlets (ADDOs) was conducted in Tanzania to improve provision of advice on artemether-lumefantrine (AL) and as a result patient adherence. An o

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Book chapters on the topic "Lumefantrina"

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Nosten, Francois, Penelope A. Phillips-Howard, and Feiko O. ter Kuile. "Other 4-Methanolquinolines, Amyl Alcohols and Phentathrenes: Mefloquine, Lumefantrine and Halofantrine." In Treatment and Prevention of Malaria. Springer Basel, 2011. http://dx.doi.org/10.1007/978-3-0346-0480-2_5.

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"Lumefantrine." In Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions. Elsevier, 2006. http://dx.doi.org/10.1016/b0-44-451005-2/00720-8.

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"Lumefantrine." In Meyler's Side Effects of Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-444-53717-1.01004-0.

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"Lumefantrine." In Drugs Handbook 2012–2013. Bloomsbury Academic, 2011. http://dx.doi.org/10.5040/9781350363595.art-1022.

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Scholar, Eric. "Lumefantrine." In xPharm: The Comprehensive Pharmacology Reference. Elsevier, 2007. http://dx.doi.org/10.1016/b978-008055232-3.62059-8.

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Price, Ric, and Julie Simpson. "Lumefantrine." In Kucers' The Use of Antibiotics Sixth Edition. CRC Press, 2010. http://dx.doi.org/10.1201/b13787-195.

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"COARTEM (Artemether/Lumefantrine)." In Antibiotics Manual. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119220787.ch41.

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"ARTEMETHER / LUMEFANTRINE ARTESUNATE." In Litt's Drug Eruptions and Reactions Manual. CRC Press, 2014. http://dx.doi.org/10.1201/b15347-22.

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Dianxi, Ning, Zhong Jingxing, and Zeng Meiyi. "Artemether and Lumefantrine Tablets (Coartem)." In Artemisinin-Based and Other Antimalarials. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-12-813133-6.00007-x.

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Ainsworth, Sean. "A." In Neonatal Formulary, edited by Sean Ainsworth. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198840787.003.0014.

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This chapter presents information on neonatal drugs that begin with A, including use, pharmacology, adverse effects, fetal and infant implications of maternal treatment, treatment, and supply of Abacavir, Acetylcysteine (N-acetylcysteine), Aciclovir = Acyclovir (USAN), Adenosine, Adrenaline = Epinephrine (rINN), Albendazole, Alginate compounds (Gaviscon®), Alimemazine (trimeprazine— former BAN and USAN), Alteplase (tissue-type plasminogen activator [rt-PA]), Amikacin, Amiodarone, Amlodipine, Amodiaquine with artesunate, Amoxicillin = Amoxycillin (former BAN), Amphotericin B, Ampicillin, Anti-v

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Conference papers on the topic "Lumefantrina"

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Souza, Mylena Andrade de, Veridiana Lenartovicz Boeira, Kamila Luiza de Toni, et al. "Recidiva de malária por Plasmodium vivax em pacientes pediátricos de região não endêmica do Brasil: relato de caso." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.13224.

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Objetivo: A malária é uma doença infecciosa grave causada por parasitas do gênero Plasmodium, com destaque para Plasmodium vivax. Em áreas não endêmicas, a identificação e o tratamento da malária representam um desafio devido à falta de familiaridade com a doença. Este estudo objetivou relatar dois casos pediátricos de malária importados de região endêmica, diagnosticados e tratados em região não endêmica, destacando a importância do diagnóstico precoce e do manejo adequado. Método: Os dados foram coletados do prontuário das pacientes atendidas em um hospital universitário. A revisão do prontu

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Lima, Giovanna de Brito Ferreira, Otávio Roberto Agabes de Barros, Emanuel Davi Lima de Matos Leão, et al. "Plasmodium sp: Uma análise interespécie dos aspectos terapêuticos, patológicos e epidemiológicos." In II SEVEN INTERNATIONAL MEDICAL AND NURSING CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/iicongressmedicalnursing-117.

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Introdução: A malária é uma doença infecciosa causada por diferentes espécies de parasitos apicomplexos pertencentes ao gênero Plasmodium, que são transmitidos às pessoas pela picada de mosquitos fêmeas infectadas do gênero Anopheles. As espécies associadas à malária humana, são elas: Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, Plasmodium knowlesi e Plasmodium falciparum. Sendo esta última espécie, a mais comum e mais grave. Por apresentar uma endemicidade dinâmica, ocorre variações na incidência e na área endêmica de um ano para outro. Assim, a redução de número de casos não deve

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Adjei-Kusi, Priscilla, Thierry Lefèvre, Esi Bart-Plange, et al. "PA-609 Pre-established plasmodium falciparum clearance by artemether-lumefantrine (AL) versus artemether-lumefantrine (AL) + atovaquone-proguanil (AP) in mosquito vectors – a study within the ASAAP project." In Abstracts of The Eleventh EDCTP Forum, 7–10 November 2023. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/bmjgh-2023-edc.250.

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Hanifah, Siti Nur, Uki Retno Budihastuti, and Eti Poncorini Pamungkasari. "Meta-Analysis: Effect of Artemether Lumefantrine on Malaria Status in Pregnant Women." In The 8th International Conference on Public Health 2021. Masters Program in Public Health, Universitas Sebelas Maret, 2021. http://dx.doi.org/10.26911/ab.epidemiology.icph.08.2021.33.

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Angwe, Martin Kamilo, Norah Mwebaza, Samson Nsombya, and Moses Ocan. "PA-324 CYP2B6*6 heterozygosity mediates slow P. falciparum clearance in malaria patients treated with Artemether-Lumefantrine." In Abstracts of The Eleventh EDCTP Forum, 7–10 November 2023. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/bmjgh-2023-edc.161.

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Thomford, Nicholas Ekow, Tracy Kellerman, Oksana Debrah, et al. "PA-113 Pharmacogenomics of drug-drug interactions in malaria-HIV con-infections: effects on generic artemether-lumefantrine therapy used in Ghana for malaria treatment." In Abstracts of The Eleventh EDCTP Forum, 7–10 November 2023. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/bmjgh-2023-edc.88.

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