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Dissertations / Theses on the topic 'Lung disorder'

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1

Bhogal, Ranjev. "The characterisation of binding sites for islet amyloid polypeptide and calcitonin gene-related peptide in mammalian lung." Thesis, Imperial College London, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261471.

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2

Pouliot, Robert A. "DEVELOPMENT AND CHARACTERIZATION OF LUNG DERIVED EXTRACELLULAR MATRIX HYDROGELS." VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4465.

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Chronic obstructive pulmonary disease (COPD) including emphysema is a devastating condition, increasing in prevalence in the US and worldwide. There remains no cure for COPD, rather only symptomatic treatments. Due to unique challenges of the lung, translation of therapies for acute lung injury to target chronic lung diseases like COPD has not been successful. We have been investigating lung derived extracellular matrix (ECM) hydrogels as a novel approach for delivery of cellular therapies to the pulmonary system. During the course of this work we have developed and characterized a lug derived
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3

Improgo, Ma Reina D. "Regulation and Function of Neuronal Nicotinic Acetylcholine Receptors in Lung Cancer: A Dissertation." eScholarship@UMMS, 2011. https://escholarship.umassmed.edu/gsbs_diss/550.

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Lung cancer is the leading cause of cancer-related mortality worldwide. The main risk factor associated with lung cancer is cigarette smoking. Research through the years suggests that nicotine in cigarettes promotes lung cancer by activating signaling pathways that lead to cell proliferation, cell survival, angiogenesis, and metastasis. Nicotine’s cellular actions are mediated by its cognate receptors, nicotinic acetylcholine receptors (nAChRs). Here, I describe the expression levels of all known human nAChR subunit genes in both normal and lung cancer cells. Of note, the genes encoding the α5
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4

Malaney, Prerna. "Significance of PTEN Phosphorylation and its Nuclear Function in Lung Cancer." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6539.

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Phosphorylation mediated inactivation of PTEN leads to multiple malignancies with increased severity. However, the consequence of such inactivation on downstream functions of PTEN are poorly understood. Therefore, the objective of my thesis is to ascertain the molecular mechanisms by which PTEN phosphorylation drives lung cancer. PTEN phosphorylation at the C-terminal serine/threonine cluster abrogates its tumor suppressor function. Despite the critical role of the PTEN C-tail in regulating its function, the crystal structure of the C-tail remains unknown. Using bioinformatics and structural a
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5

Lee, Sherman. "The effect of acute cigarette smoke exposure on regional pulmonary blood flow, volume, red cell transit and polymorphonuclear leukocyte retention in the rabbit lung." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/24840.

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Regional pulmonary blood flow and volume was measured in ten rabbits anesthetized with pentobarbital (30 mg/kg). Tracheostomy was performed and catheters were placed into the jugular vein and carotid artery. The cardiac ⁹⁹mtc output was measured using the indicator-dilution technique using Tc labelled RBC followed by an injection of radiolabelled macroaggregates (MAA) to mark regional blood flow. Measurements were made both before and after either exposure to cigarette smoke (3 cigarettes for ten minutes at 4 puffs/minute) or sham exposure to air. The animals were sacrificed and the lungs w
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6

Langhammer, Arnulf. "Respiratory symptoms, lung function, and bone mineral density in a comprehensive population study : The Nord-Trøndelag Health Study 1995-97, The Bronchial Obstruction in Nord-Trøndelag Study." Doctoral thesis, Norwegian University of Science and Technology, Faculty of Medicine, 2003. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-126.

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<p>The prevalence of respiratory symptoms and diseases like asthma and chronic obstructive pulmonary disease (COPD), seem to have increased the last decades. The reason for the increase in asthma related symptoms and allergy is uncertain. Some, but not all, of this increase might be ascribed to lowered threshold for use of the diagnosis by medical doctors, change in diagnostic criteria, and increased awareness of symptoms in the population. Studies have indicated that increased prevalence might be explained by a reduction during the last decades in exposure to environmental factors in infancy,
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7

Ekta, Rani. "Ayurvedic ways to treat lung disorders." Thesis, Буковинський державний медичний університет, 2012. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/1422.

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8

Heeley, Emma Louise. "Lung surfactant and secretory phospholipase A←2 in inflammatory lung disorders." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323970.

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9

Kotecha, Sailesh. "The role of cytokines in chronic lung disease of prematurity." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244032.

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10

Gonzalez, Brian David. "Prevalence, Predictors, and Correlates of Patient Concealment of a Lung Cancer Diagnosis." Scholar Commons, 2013. http://scholarcommons.usf.edu/etd/4679.

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Most cases of lung cancer have a commonly-understood behavioral etiology. Thus, individuals with lung cancer are often blamed for their illness by others and may therefore seek to avoid this blame by concealing their diagnosis from others. This study sought to determine the prevalence of diagnosis concealment, examine potential predictors of concealment, and test parts of a cognitive-affective-behavioral model of the effects of concealing a concealable stigma among individuals receiving treatment for lung cancer. With regard to predictors of concealment, it was hypothesized that concealment wo
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11

Jones, Mark Philip. "A low frequency acoustic method for detecting abnormalities in the human thorax." Thesis, University of Southampton, 1996. https://eprints.soton.ac.uk/253034/.

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12

Schins, Peter Frans Roeland. "Biomarkers of mineral dust induced lung disorders molecular epidemiologic studies in coal workers /." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 1996. http://arno.unimaas.nl/show.cgi?fid=6697.

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13

Clayton, Nicola. "The effect of COPD on laryngopharyngeal sensitivity and swallow function." Connect to full text, 2007. http://hdl.handle.net/2123/2236.

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Thesis (M. Sc. Med.)--University of Sydney, 2008.<br>Title from title screen (viewed 29 July 2008). Submitted in fulfilment of the requirements for the degree of Master of Science in Medicine to the Discipline of Medicine, Faculty of Medicine. Degree awarded 2008; thesis submitted 2007. Includes bibliographical references. Also available in print form.
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14

Gonzalez, Brian D. "Depression in Lung Cancer Patients: Role of Perceived Stigma." Scholar Commons, 2010. https://scholarcommons.usf.edu/etd/1645.

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Previous research suggests that lung cancer patients are at an increased risk for depressive symptomatology; however, little is known about the possible etiology or correlates of depression among these patients. This study examined the relationship between perceived stigma and depressive symptomatology among lung cancer patients, and sought to find potential mediators of this relationship. It was hypothesized that more perceived stigma would be related to greater depressive symptomatology and that perceived stigma would contribute unique variance to depressive symptomatology above and beyond t
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15

Zaetta, Cristina. "Disastro del Vajont: conseguenze a lungo termine sulla salute psichica e fisica dei sopravvissuti." Doctoral thesis, Università degli studi di Padova, 2008. http://hdl.handle.net/11577/3425042.

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BACKGROUND AND AIMS The negative impact of traumatic events on psychological functioning has been well-established (Wagner, 2000). Recent research suggests that trauma may have deleterious effects on physical functioning (Schnurr, 1996). Some research (Lauterbach, 2005) indicates that the relationship between traumatic experiences and health problems could be mediated by post-traumatic stress disorder (PTSD) or depression (MDD). Experts (Ford et al., 2004) suggest that only long term studies may allow to understand the trauma exposure consequences on physical health from a statistical-epi
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16

Böhm, Birgitta. "Risk and resilience in children born preterm : cognitive and executive functioning at 5 1/2 years of age /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-729-0/.

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17

Hedlund, Ulf. "Occupational air pollutants and non-malignant respiratory disorders especially in miners : the obstructive lung disease in Northern Sweden studies : thesis IX /." Doctoral thesis, Umeå universitet, Yrkes- och miljömedicin, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1591.

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Aim. To assess associations between occupational air pollution and respiratory health, especially in miners. Background. Indications of associations between occupational exposure or social economic status and respiratory health have been found in several population-based studies. However, there have been few longitudinal studies of the putative correlations, the effects of environmental and genetic factors have seldom been simultaneously studied, and studies of miners have generated conflicting results. Material and methods. Population-based Obstructive Lung Disease in Northern Sweden (OLIN) c
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18

Sargurupremraj, Muralidharan [Verfasser], Bertram [Akademischer Betreuer] [Gutachter] Müller-Myhsok, and Johannes [Gutachter] Beckers. "Genetics of complex lung disorders - new approaches in asthma and COPD / Muralidharan Sargurupremraj ; Gutachter: Bertram Müller-Myhsok, Johannes Beckers ; Betreuer: Bertram Müller-Myhsok." München : Universitätsbibliothek der TU München, 2017. http://d-nb.info/1133261922/34.

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19

Doke, Mayur Arvind. "The Role of ID3 and PCB153 in the Hyperproliferation and Dysregulation of Lung Endothelial Cells." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3808.

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Uncontrolled growth of vascular stem cells as a result of endothelial-mesenchymal transition is considered to cause hyper-proliferative vascular remodeling in severe pulmonary arterial hypertension (PAH) patients. Hyperplastic intimal growth is one of the causes of closure of the lumen of pulmonary arterioles. This abnormal vessel remodeling leads to the progressive increase in pressure of the pulmonary arterioles causing severe PAH; and debilitating harm to patients resulting in mortality from right heart failure. Environmental factors, including polychlorinated biphenyls (PCBs), are consider
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20

McNaughton, Lance. "Nitric oxide and matrix metalloproteinases as mediators of chronic and acute inflammatory disorders in humans, focus on chronic liver damage and acute lung injury." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0010/NQ59635.pdf.

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21

Saraiva, Cristina Maria da Silva. "A qualidade de vida dos doentes com insuficiência respiratória crónica submetidos a ventilação não invasiva." Master's thesis, Instituto Superior de Psicologia Aplicada, 2003. http://hdl.handle.net/10400.12/907.

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Dissertação de Mestrado em Psicologia da Saúde<br>A Ventilação Não invasiva (VNl) associada à Oxigenoterapia de Longa Duração (OLD) tem sido largamente usada, na última década do século XX, em situações clínicas com compromisso respiratório crónico para correcção das síndromes hipoventilatórias. O principal objectivo deste estudo foi averiguar em que medida a VNl influencia a Qualidade de Vida (QDV) dos doentes com Insuficiência Respiratória Crónica (IRC) estabilizada. A amostra é constituída por 92 participantes distribuídos por três grupos sendo a média de idade de 66,51 anos, compreendida
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22

Uddenfeldt, Per. "Primary biliary cirrhosis : an epidemiological and clinical study based on patients from northern Sweden." Doctoral thesis, Umeå universitet, Medicin, 1990. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96911.

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Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease, which primarily affects middle-aged women. The liver histology is characterized by inflammation and destruction of the intrahepatic bile ducts as well as a high frequency of granuloma. Although the etiology is unknown, the occurrence of associated multiorganic abnormalities such as Sjogren's syndrome, scleroderma, rheumatic disorders and thyroid gland diseases have been cited as evidence favouring an autoimmune background. Addison and Gull in 1851 described the first patient with jaundice and xanthomatosis. PBC was first m
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23

Karlsson, Emma, and Marcus Sonesson. "Jämförelse av energiomsättning och aktivitetsnivå vid fysisk aktivitet mellan barn med cystisk fibros och en frisk kontrollgrupp." Thesis, Uppsala University, Department of Public Health and Caring Sciences, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-125560.

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<p><strong>Aim:</strong> The aim of this study was to describe the total energy expenditure (TEE) and physical activity levels (PAL) within a group of children with cystic fibrosis (CF) and to compare the results with a control group with healthy children. The aim also was to compare the rated activity levels between the groups as well comparing the difference between boys and girls within the groups. <strong>Method:</strong> The study included 30 participating children, divided into two groups with 15 participants in each group. One of the groups was a CF-group and the other a group of contro
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24

RAMOS, Beatriz Peixoto. "AVALIAÇÃO HISTOLOGICA DE PULMÃO DE BOVINOS DA RAÇA NELORE TERMINADOS A PASTO E EM CONFINAMENTO." Universidade Federal de Goiás, 2009. http://repositorio.bc.ufg.br/tede/handle/tde/914.

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Made available in DSpace on 2014-07-29T15:07:48Z (GMT). No. of bitstreams: 1 pre text Beatriz Ramos.pdf: 242782 bytes, checksum: 4f6eca15517b15a8eaaf87c4005fdd33 (MD5) Previous issue date: 2009-02-13<br>Most Brazilian states have common features, as the problems that affect the health of animals. Infectious and contagious diseases, parasites, and metabolic deficiencies, are of great importance, directly interfering in economic indicators. Respiratory diseases have highlighted the various systems of breeding cattle, because they have lung particular characteristics making them more vulnerable
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25

MORAIS, Caio César Araújo. "Aplicabilidade de técnicas de expansão pulmonar em pacientes com comprometimento no nível de consciência." Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/18326.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2017-02-15T13:58:43Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação_Caio_Morais_UFPE_biblccs_v4_07.pdf: 2958381 bytes, checksum: 1504e0cbe3d131daab3b28990bf82f6d (MD5)<br>Made available in DSpace on 2017-02-15T13:58:43Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação_Caio_Morais_UFPE_biblccs_v4_07.pdf: 2958381 bytes, checksum: 1504e0cbe3d131daab3b28990bf82f6d (MD5) Previous issue date: 2015-03-06<
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26

Pinal, Fernández Iago. "Estudio de nuevas técnicas de imagen en la evaluación y seguimiento de la neumopatía intersticial en las enfermedades autoinmunes sistémicas." Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/285194.

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La tomografía computarizada de alta resolución (TCAR) es la prueba de referencia para la valoración de las alteraciones estructurales del parénquima pulmonar en la enfermedad pulmonar intersticial (EPI) de las enfermedades autoinmunes sistémicas, también denominadas enfermedades del tejido conectivo (ETC). Junto con las pruebas de función respiratoria (PFRs), esenciales para el estudio del funcionalismo pulmonar de estos pacientes, la TCAR es la herramienta más útil para el diagnóstico y seguimiento de la EPI en estos pacientes. Muchos de los pacientes que presentan ETC son jóvenes, alg
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27

Pavlikhina, Ekaterina. "Vliv zmeny postury na respiracni funkce u pacientu s postižením michy." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-396995.

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Author: Bc. Pavlikhina Ekaterina Title: Influence of the posture's change on respiratory function in spinal cord injury patients. Objectives: The purpose of this thesis is to analyze change in respiratory function on change of posture in patients with spinal cord injury (SCI). Another objective is to compare the respiratory functions in a health subjects and in a SCI patients. Last but not least is an effort to find out whether SCI patients have a pattern of restrictive pulmonary dysfunction. The findings can help understanding development of respiratory complications after spinal cord injury.
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28

Jenkins, Heather Mary Leanne. "Involuntary breath stacking in children with neuromuscular disorders." 2011. http://hdl.handle.net/1993/4520.

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ABSTRACT Rationale: Respiratory insufficiency is one of the most common causes of death in patients with neuromuscular disorders (NMD). Due to weakness and cognitive level, children with NMD often cannot perform required maneuvers to recruit lung volume. Data from cooperative adults suggest that breath stacking with a mask and one-way valve can obtain significantly higher lung volumes. Methods: To study the effectiveness of a breath stacking mask in patients with NMD, we studied 23 children (17 male, 6 female) over 3 years, mean age 11 y (range 3-19 y) and body mass 43.8 kg (range 12-80
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29

Landini, Nicholas. "Characterization of Connective Tissue Disorders related Interstitial Lung Disease (CTD-ILD) with Computed Tomography (CT) and Magnetic Resonance Imaging (MRI)." Doctoral thesis, 2022. http://hdl.handle.net/2158/1260834.

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Purpose/Objectives Interstitial Lung Disease (ILD) is a major complication of Systemic Sclerosis (SSc), with high morbidity and mortality. Computed tomography is the gold standard for ILD imaging assessment. However, recent Ultra-Short Echo-Time (UTE) Magnetic Resonance Imaging (MRI) sequences are promising for lung parenchyma evaluation. Moreover, different Dynamic Contrast Enhancement (DCE) MRI patterns seems able to identify prevalent inflammatory and fibrotic ILD, with possible implications in the management of the therapy. We aimed to verify the reliability of respiratory triggered UTE S
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30

Green, Robin J. "Atopy and acquired immune deficiency - issues of control of two extremes of a spectrum of paediatric respiratory disorders with an immunological basis." Thesis, 2013. http://hdl.handle.net/2263/32940.

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Twenty publications are submitted. All deal with the issues of control of two ends of the spectrum of immune-mediated respiratory disorders in children, namely atopic (asthma and allergic rhinitis) and HIV-related lung disease. This submission summarises the research by the author into this spectrum of lung diseases of children in South Africa, highlighting the diversity of conditions that are not only clinically important, but also common. Understanding of all conditions is required to improve the health of children in this region. Management of chronic conditions requires two major en
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31

Larsson, Lars-Gunnar. "Snoring and other symptoms related to obstructive sleep apnea : prevalence, risk factors, and relation to respiratory disorders : the obstructive lung disease in Northern Sweden study III." Doctoral thesis, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-110671.

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32

Chen, Jian-Jung, and 陳建仲. "Contemporary Study of Tongue Diagnosis of Chinese Medicine An Additional Study about The Relationship of Tongue States to Functional Disorders of the Lung in Chronic Obstructive Pulmonary Diseases." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/19541458698748940911.

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博士<br>中國醫藥學院<br>中國醫學研究所<br>87<br>The aim of this thesis is to establish the scientific bases of Chinese medical tongue diagnosis. The first step is to create the best environment for taking accurate photographs of the tongue. The second is to apply the color model to automatically visually separate the tongue fur and tongue body. The third step is to investigate the relationship of tongue states to functional disorders of the lung in chronic obstructive lung diseases in the clinical context. The environment created was as follows: RB5000 light set with color-temperature of 5,300o
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