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Journal articles on the topic 'Lung disorder'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Rannels, S. R., S. L. Rannels, J. G. Sneyd, and E. G. Loten. "Fetal lung development in rats with a glycogen storage disorder." American Journal of Physiology-Lung Cellular and Molecular Physiology 260, no. 6 (1991): L419—L427. http://dx.doi.org/10.1152/ajplung.1991.260.6.l419.

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A New Zealand strain of rats (NZR/Mh) is unable to mobilize liver glycogen due to a deficiency of phosphorylase b kinase. Affected homozygous rats (gsd/gsd) were used to assess the developmental relationship between lung glycogen loss and surfactant phospholipid and protein biosynthesis. Phosphorylase a and phosphorylase b kinase activities were negligible in gsd/gsd fetal lungs compared with controls from gestational day (D18) until postnatal day 1 (D + 1). At D20, tissue glycogen content was 158 +/- 5 and 181 +/- 6 mumol/g lung for control and gsd/gsd, respectively. Control rats mobilized 84

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Bakhtiar, Arief, and Renny Irviana Eka Tantri. "Faal Paru Dinamis." Jurnal Respirasi 3, no. 3 (2019): 89. http://dx.doi.org/10.20473/jr.v3-i.3.2017.89-96.

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Pulmonary function is an examination to measure lung volume function using spirometry. Tests with spirometry to detect abnormalities associated with respiratory distress. Spirometry examination is not only to determine the diagnosis but also to assess the severity of obstruction, restriction, and the effects of treatment. Spirometry examination is a test to measure the volume of a person’s static and dynamic lungs with a spirometer tool. Dynamic lung spirometry consists of Forced vital capacity (FVC), Forced expiratory volume (FEVT), Forced expiratory flow200-1200 / FEF 200-1200, Forced expira

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Ilyina, N. A., S. L. Ivanov, I. E. Myagkova, and K. V. Prusakova. "The role of radiological research methods in the diagnosis of rare forms of interstitial lung diseases in newborns." Regional blood circulation and microcirculation 22, no. 1 (2023): 92–102. http://dx.doi.org/10.24884/1682-6655-2023-22-1-92-102.

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Introduction. Interstitial lung diseases in newborns associated with diffuse pulmonary developmental disorders are a difficult to detect, as they are rare, formed at the early stages of embryonic development, clinically manifested in the first hours of life as severe respiratory distress syndrome in newborns. The aim. To demonstrate the role of radiation research methods and the difficulties of differential diagnosis of rare forms of interstitial lung diseases associated with diffuse impaired lung development. Materials and methods. Clinical cases of congenital alveolar dysplasia and alveolar-

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Mehta, Pankaj, and Girish Trikha. "Lymphoproliferative Disorder of the Lung." Chest 140, no. 4 (2011): 69A. http://dx.doi.org/10.1378/chest.1113561.

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Mitka, Mike. "Researchers Explore Rare Lung Disorder." JAMA 297, no. 5 (2007): 456. http://dx.doi.org/10.1001/jama.297.5.456.

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6

Garrett, M. Kathryn. "Combined lung and bone disorder." Seminars in Roentgenology 20, no. 4 (1985): 323–24. http://dx.doi.org/10.1016/0037-198x(85)90039-2.

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7

Sinha, Tanay, Harshita Mishra, Rosna Thomas, et al. "A case of post renal transplant PTLD of lung." Lung India 40, no. 5 (2023): 465–68. http://dx.doi.org/10.4103/lungindia.lungindia_94_23.

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ABSTRACT Post Transplant Lymphoproliferative Disorder (PTLD) is a heterogeneous group of Lymphoid proliferative disorders that occur in patients post Hematogenous or Solid organ transplants. They are closely associated with Ebstein-Barr Virus and can range from polyclonal lesions to frank lymphomas. PTLD is usually a rare post-transplant complication, with the incidence being higher post Lung or Heart Transplantation and less commonly seen post-renal transplantation. The incidence post renal transplantation is less than 1%, with most of the cases being limited to the Gastro-Intestinal Tract an

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Kadir, M. Abdul, Tanvir Noor Baig, and K. Siddique-e. Rabbani. "FOCUSED IMPEDANCE METHOD TO DETECT LOCALIZED LUNG VENTILATION DISORDERS IN COMBINATION WITH CONVENTIONAL SPIROMETRY." Biomedical Engineering: Applications, Basis and Communications 27, no. 03 (2015): 1550029. http://dx.doi.org/10.4015/s1016237215500295.

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Conventional spirometry gives information on the overall ventilation of a person's lung; it cannot detect localized disorders in ventilation as occurring in pulmonary edema, pneumonia, tumor, TB, etc. Here we propose a new technique involving the recently developed focused impedance method (FIM) in combination with conventional spirometry to detect localized lung ventilation disorders. Electrical impedance of lung tissue changes as a function of air content and FIM provides a measurement of localized electrical impedance with sensitivity down to reasonable depths inside the body using a few su

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Agustiyanto, Catur, and Ariani Permatasari. "Farmer’s Lung Disease." Jurnal Respirasi 7, no. 3 (2021): 152. http://dx.doi.org/10.20473/jr.v7-i.3.2021.152-157.

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Occupational lung disease is a lung disease or disorder that occurs due to the inhalation of dangerous particles, mist, vapors, or gases while a person is working. The materials accumulate in the respiratory tract or lungs. The type of lung disease that occurs depends on the size and type of the inhaled material. Substances that cause occupational lung disease are toxic materials called noksa. Noksa is a substance that can cause damage to the anatomical structure of body organs and cause respiratory tract function disorders. The lung disease that many farmers experience is often called farmer'

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Zinkin, Valery, Irina Vasilyeva, Vladimir Bespalov, and Aleksandr Osetrov. "HIGH-INTENSITY LOW-FREQUENCY ACOUSTIC VIBRATIONS HAVE THE CRITICAL EFFECT ON THE LUNGS." Akustika 32 (March 1, 2019): 5–9. http://dx.doi.org/10.36336/akustika2019325.

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The paper summarizes the findings of experimental studies on animals and literature data to show the characteristics of the lungs exposure to low-frequency acoustic vibrations. Experimental studies were performed on laboratory animals of different species (mice, rats, rabbits, dogs) exposed to low-frequency acoustic vibrations on the test bench set for several months. To assess lung injury, broncho-alveolar lavage, surfactant, biologically active substances in the tissues of the lung, extracellular low-molecular blood DNA were investigated, computerized tomography and postmortem methods were u

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Lorensia, Amelia, Rivan Virlando Suryadinata, and I. Nyoman Yoga Diputra. "Risk Factors and Early Symptoms Related to Respiratory Disease in Pedicab Drivers in Surabaya." Jurnal Kesehatan Masyarakat 15, no. 2 (2019): 223–34. http://dx.doi.org/10.15294/kemas.v15i2.19255.

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Various factors which cause respiratory diseases such as smoking, air pollution, and disease history are found in pedicab. The purpose of this study was to understand the risk factors and early symptoms that related to respiratory disease in pedicab drivers. This study used observational cross-sectional design with purposive sampling. Variables that were recorded in this study were lung function risk factors and early symptoms of respiratory disorders. The number of samples was 148 respondents (135 with respiratory disorder and 13 without respiratory disorder). The results of this study found

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Turkalj, Mirjana, Vesna Miranović, Rajka Lulić-Jurjević, Romana Gjergja Juraški, and Dragan Primorac. "Cardiorespiratory complications in patients with osteogenesis imperfecta." Paediatria Croatica 61, no. 3 (2017): 106–12. http://dx.doi.org/10.13112/pc.517.

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Osteogenesis imperfecta (OI) is a hereditary connective tissue disorder, usually caused by dominant mutations of genes coding forcollagen type I alpha chains, COL1A1/A2. Although skeletal manifestations of OI are most readily observable, cardiopulmonarydisorders in patients with OI are increasingly recognized as life-threatening but treatable disorders. Unfortunately, the majority ofpatients with moderate to severe types of OI die from or with cardiopulmonary complications. The lungs and the heart are oftenunrecognizable and neglected organs in patients with OI. In monitoring of patients with

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Reynders, C. S., G. J. Whitman, and F. S. Chew. "Posttransplant lymphoproliferative disorder of the lung." American Journal of Roentgenology 165, no. 5 (1995): 1118. http://dx.doi.org/10.2214/ajr.165.5.7572486.

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Nishinakamura, R., R. Wiler, U. Dirksen, et al. "The pulmonary alveolar proteinosis in granulocyte macrophage colony-stimulating factor/interleukins 3/5 beta c receptor-deficient mice is reversed by bone marrow transplantation." Journal of Experimental Medicine 183, no. 6 (1996): 2657–62. http://dx.doi.org/10.1084/jem.183.6.2657.

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Mice mutant for granulocyte macrophage colony-stimulating factor (GM-CSF) or the common receptor component (beta c) for GM-CSF, interleukin (IL)-3, and IL-5 exhibit a lung disorder similar to human pulmonary alveolar proteinosis, a rare disease with congenital, infantile, and adult forms. Bone marrow transplantation and hematopoietic reconstitution of beta c mutant mice with wild-type bone marrow reversed the established disease state in the lungs, defining this disease as hematopoietic in nature. It is likely that the disease involves alveolar macrophages, as donor myeloid cell engraftment in

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Cordina-Duverger, Emilie, Shreeshti Uchai, Nastassia Tvardik, et al. "Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)." International Journal of Environmental Research and Public Health 19, no. 23 (2022): 16246. http://dx.doi.org/10.3390/ijerph192316246.

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Circadian rhythm disruption due to night shift work and/or sleep disorders is associated with negative health outcomes including cancer. There is only scant evidence of an association with lung cancer, unlike breast and prostate cancer. We explore the role of sleep disorders and night shift work in lung cancer risk among women in a population-based case-control study, including 716 lung cancer cases and 758 controls. Multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) associated with sleep duration per day (<7 h, 7–7.9 h, ≥8 h),

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Cîrjaliu, Roxana Elena, Ioan Anton Arghir, Enis Beitula, et al. "Lung function testing assessment by impulse oscillometry in chronic lung disease." Romanian Journal of Occupational Medicine 71, no. 1 (2020): 42–48. http://dx.doi.org/10.2478/rjom-2020-0006.

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AbstractImpulse oscillometry (IOS) is a variant of forced oscillation technique described by Dubois 50 years ago, which allows us to measure the reactance of the airways and the resistance of the small and large airways during tidal breathing. It requires minimal patient cooperation from subjects who are unable to perform spirometry, like elders, children and patients with neurologic disorders. IOS can outline the diagnosis of obstructive airway disease, differentiate small airway obstruction from large airway obstruction. It is more sensitive than spirometry for peripheral airway disease in d

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Taveira-DaSilva, Angelo M., Thomas C. Markello, David E. Kleiner, et al. "Expanding the phenotype of COPA syndrome: a kindred with typical and atypical features." Journal of Medical Genetics 56, no. 11 (2018): 778–82. http://dx.doi.org/10.1136/jmedgenet-2018-105560.

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BackgroundCopa syndrome is a rare autosomal dominant disorder with abnormal intracellular vesicle trafficking. The objective of this work is to expand the knowledge about this disorder by delineating phenotypic features of an unreported COPA family.Methods and resultsA heterozygous missense variant (c.698 G>A, p.Arg233His) in COPA was identified in four members of a three-generation kindred with lung, autoimmune and malignant disease of unknown aetiology. Ages of onset were 56, 26, 16 and 1 year, with earlier age of onset in successive generations. Presenting symptoms were cough and dyspnoe

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Corredor-Orlandelli, David, Camila Borda, Juan Sebastian Sierra, and Daniel Gerardo Fernández-Ávila. "Multiple-autoimmune syndrome causing interstitial lung disease in the presence of pulmonary hypertension and Erasmus syndrome." Rheumatology (Bulgaria) 31, no. 4 (2024): 123–28. http://dx.doi.org/10.35465/31.4.2023.pp123-128.

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Connective tissue diseases constitute a group of inflammatory disorders that can concurrently affect multiple organs. Pulmonary manifestations of connective tissue diseases include interstitial lung disease, pulmonary hypertension, pleural diseases, and airway compromise. Both interstitial lung disease and pulmonary arterial hypertension have high morbidity and mortality in these patients. Interstitial lung disease affects 40 % - 50 % of patients with connective tissue diseases, predominantly systemic sclerosis, rheumatoid arthritis, and inflammatory myopathies. Parenchymal compromise is heter

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19

Ardam, Kiky Aunillah Yolanda. "HUBUNGAN PAPARAN DEBU DAN LAMA PAPARAN DENGAN GANGGUAN FAAL PARU PEKERJA OVERHAUL POWER PLANT." Indonesian Journal of Occupational Safety and Health 4, no. 2 (2017): 155. http://dx.doi.org/10.20473/ijosh.v4i2.2015.155-166.

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ABSTRACTDust exposure in the working environment is a potential factor to cause lung function disorders. Lung function disorders such as restriction, obstruction, and mixed-type which is indicated by decreasing % FEV and % FVC. Overhaul power plant workers have high risk dust exposure in the working environment as impact of the process overhaul power plant machine. Dust from overhaul work can entry to the respiratory tract of the workers through inhalation. The purpose was to analyze the relationship of total dust exposure and exposure time with lung function disorder among overhaul power plan

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Li, Xuanfei, Zheng Liu, He Jin та ін. "Agmatine Protects against Zymosan-Induced Acute Lung Injury in Mice by Inhibiting NF-κB-Mediated Inflammatory Response". BioMed Research International 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/583736.

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Acute lung injury (ALI) is characterized by overwhelming lung inflammation and anti-inflammation treatment is proposed to be a therapeutic strategy for ALI. Agmatine, a cationic polyamine formed by decarboxylation of L-arginine, is an endogenous neuromodulator that plays protective roles in diverse central nervous system (CNS) disorders. Consistent with its neuromodulatory and neuroprotective properties, agmatine has been reported to have beneficial effects on depression, anxiety, hypoxic ischemia, Parkinson’s disease, and gastric disorder. In this study, we tested the effect of agmatine on th

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Soldati, Gino, Andrea Smargiassi, Libertario Demi, and Riccardo Inchingolo. "Artifactual Lung Ultrasonography: It Is a Matter of Traps, Order, and Disorder." Applied Sciences 10, no. 5 (2020): 1570. http://dx.doi.org/10.3390/app10051570.

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When inspecting the lung with standard ultrasound B-mode imaging, numerous artifacts can be visualized. These artifacts are useful to recognize and evaluate several pathological conditions in Emergency and Intensive Care Medicine. More recently, the interest of the Pulmonologists has turned to the echographic study of the interstitial pathology of the lung. In fact, all lung pathologies which increase the density of the tissue, and do not consolidate the organ, are characterized by the presence of ultrasound artifacts. Many studies of the past have only assessed the number of vertical artifact

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Sari, Maya Puspita, and Corie Indria Prasasti. "OVERVIEW OF WORKERS' PULMONARY FAAL CONDITIONS AND WORKER ACTIONS AT THE END OF THE FINAL SCRUB INDUSTRY X SURABAYA." Indonesian Journal of Public Health 15, no. 1 (2020): 25. http://dx.doi.org/10.20473/ijph.v15i1.2020.25-36.

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ABSTRACTOne type of air pollution that has the potential to harm human health is particulate dust. Particulate dust causes pulmonary damage when inhaled during work continuously. The purpose of this study was to see the description of the condition of the lung physiology ,workers' actions,worker smoking habits,use of respiratory tract,and physical quality of the environment. This was descriptive research, using design cross-sectional. The sample size used total population as 14 people. physical environmental quality includes PM2.5 concentration,air temperature and humidity. The action variable

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Engin, Muhammet Mesut Nezir, and Öner Özdemir. "Current mechanisms in the pathogenesis of lung fibrosis." Trends in Immunotherapy 7, no. 1 (2023): 2028. http://dx.doi.org/10.24294/ti.v7.i1.2028.

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Pulmonary fibrosis is a diverse group of lung disorders defined by varying degrees of fibrosis and inflammation in the pulmonary parenchyma. While it may be caused by a known disease, e.g., autoimmune or connective tissue disorder, drugs, hypersensitivity to inhaled organic antigens, or sarcoidosis, it also occurs to be idiopathic. When we examine the pathogenesis of lung fibrosis, we see that cellular aging plays a major role. Lung fibroblasts play an active role in the regeneration process. However, despite all the information, the pathogenesis of lung fibrosis is not clearly understood. It

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Aribowo, Kornelis, and Wiwi Monica Sari. "Hematological Side Effects Management of Paclitaxel - Carboplatin Chemotherapy in Lung Cancer." MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan 10, no. 1 (2023): 129. http://dx.doi.org/10.26714/magnamed.10.1.2023.129-140.

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Background: Paclitaxel-carboplatin chemotherapy can cause hema-tological disorders. This regiment's hematological side effects include anemia, neutropenia, and thrombocytopenia. Data showed this regiment side effect occurs with grade iii/iv toxicity anemia, grade III/IV anemia by 41%, neutropenia (78%), and thrombocytopenia (41%). This hema-tological disorder occurs in bone marrow-producing areas due to chemotherapy. Each hematological disorder requires separate interven-tion.Case Presentation: A 54-year-old woman was diagnosed with a progressive disease of left lung adenocarcinoma (Exon 21 mu

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Locke, Brian W., Janet J. Lee, and Krishna M. Sundar. "OSA and Chronic Respiratory Disease: Mechanisms and Epidemiology." International Journal of Environmental Research and Public Health 19, no. 9 (2022): 5473. http://dx.doi.org/10.3390/ijerph19095473.

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Obstructive sleep apnea (OSA) is a highly prevalent disorder that has profound implications on the outcomes of patients with chronic lung disease. The hallmark of OSA is a collapse of the oropharynx resulting in a transient reduction in airflow, large intrathoracic pressure swings, and intermittent hypoxia and hypercapnia. The subsequent cytokine-mediated inflammatory cascade, coupled with tractional lung injury, damages the lungs and may worsen several conditions, including chronic obstructive pulmonary disease, asthma, interstitial lung disease, and pulmonary hypertension. Further complicati

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Wispriyono, Bambang, Elia Yulaeva, Budi Hartono, and Satria Pratama. "Indoor Air Pollution (Carbon Dioxide and Total Volatile Organic Compound) and Pulmonary Disorders in Junior High School Students in Depok, West Java." Global Journal of Health Science 11, no. 12 (2019): 45. http://dx.doi.org/10.5539/gjhs.v11n12p45.

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Good indoor air quality in the school environment is crucial for health and productivity of the students. Indoor air pollution needs to be taken into consideration, given that one can spend 90% of their time indoor. CO2 and Total VOC is an indoor pollutant that causes pulmonary disorder. This research is to investigate the relationship between exposure of CO2, concentration, total VOC and pulmonary disorder in Junior High School students. This research used cross-sectional design conducted on March - May 2018. The samples were 139 students taken by using simple random sampling. CO2 value was m

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Каменева, Марина, Marina Kameneva, Артем Тишков, Artem Tishkov, Василий Трофимов, and Vasiliy Trofimov. "NEW APPROACHES TO DIFFERENTIAL DIAGNOSTICS OF SYNDROMES OF VENTILATION DISORDERS." Bulletin physiology and pathology of respiration 1, no. 65 (2017): 8–15. http://dx.doi.org/10.12737/article_59aca3bd1aa8e8.39408462.

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The study objective is to develop a new algorithm for diagnosing lung function disorder types. A retrospective analysis of lung function tests results (spirometry, body plethysmography and lung elasticity measurement with the esophageal balloon) was performed in 575 patients with diffuse parenchymal lung diseases. The algorithm, recommended by the expert commission of American Thoracic Society and European Respiratory Society in 2005, showed low sensitivity: disturbances of respiratory mechanics were determined only in 43% of cases. The proposed algorithm, based on the analysis of vital capaci

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Yoshino, Ryusei, Nana Yoshida, Shunsuke Yasuda, et al. "Synchronous multiple lung cancers with hilar lymph node metastasis of small cell carcinoma: A case report." World Journal of Clinical Cases 11, no. 25 (2023): 5919–25. http://dx.doi.org/10.12998/wjcc.v11.i25.5919.

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Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophys

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Koirala, Puru, Narendra Bhatta, Ram Hari Ghimire, Deebya Raj Mishra, Bidesh Bista, and Bhupendra Shah. "Overlap of Sleep Disorders and Chronic Respiratory Diseases: An Emerging Health Dilemma." Nepalese Medical Journal 2, no. 2 (2019): 243–49. http://dx.doi.org/10.3126/nmj.v2i2.26007.

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Introduction: The burden of Overlap Syndrome (coexistence of sleep-related breathing disorders in patients with respiratory diseases) is high in developing countries, and such a phenomenon implies higher morbidity. The study was conducted to measure the prevalence of sleep-related breathing disorders in patients with Respiratory Symptom Complex and to identify factors associated with the severity of sleep-related breathing disorders.Materials and Methods: A hospital-based cross-sectional study of 50 patients with respiratory symptom complex was conducted at BP Koirala Institute of Health Scien

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Monforte-Muñoz, Hector, Neena Kapoor, and Jorge Albores Saavedra. "Epstein-Barr Virus-associated Leiomyomatosis and Posttransplant Lymphoproliferative Disorder in a Child with Severe Combined Immunodeficiency: Case Report and Review of the Literature." Pediatric and Developmental Pathology 6, no. 5 (2003): 449–57. http://dx.doi.org/10.1007/s10024-003-8096-x.

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The occurrence of smooth muscle neoplasms and lymphoproliferative disorders in immunocompromised patients is well recognized. We report the case of an 8-year-old girl with adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID) status post-bone marrow transplant (BMT), in whom Epstein-Barr virus (EBV) was detected in innumerable leiomyomas involving the gallbladder (leiomyomatosis), and multifocal leiomyomas in liver, spleen, pancreas, intestinal tract, and lung. The leiomyomas of the gallbladder, liver, spleen, and lung were asymptomatic, while those located in the colon b

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Muchtar, Eli, Mordechai R. Kramer, Liat Vidal, et al. "Posttransplantation Lymphoproliferative Disorder in Lung Transplant Recipients." Transplantation Journal 96, no. 7 (2013): 657–63. http://dx.doi.org/10.1097/tp.0b013e31829b0718.

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Murphy, Raymond L. "Lung Sound Patterns in Common Pulmonary Disorder." Chest 124, no. 4 (2003): 190S. http://dx.doi.org/10.1378/chest.124.4_meetingabstracts.190s-a.

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Salman, S., S. Asghar, M. Usman, et al. "Substance use disorder, lung cancer, and COPD." Respiratory Medicine 132 (November 2017): 278–79. http://dx.doi.org/10.1016/j.rmed.2017.07.050.

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Haji, Hassan A., Douglas S. Corwin, Jennifer Y. So, and Robert M. Reed. "Lymphoproliferative disorder in a lung transplant recipient." BMJ Case Reports 13, no. 3 (2020): e234532. http://dx.doi.org/10.1136/bcr-2020-234532.

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Post-transplantation lymphoproliferative disorder (PTLD) is uncommon following solid organ transplantation. We present a case of PTLD presenting as hematochezia and abdominal pain in a 66-year-old man, who had undergone bilateral lung transplantation with alemtuzumab induction 7 months prior to presentation. The transplant serologic status was “high-risk” for the presence of both Epstein-Barr virus (EBV) serologies in the donor and negative serologies in the recipient. Biopsies taken during colonoscopy stained strongly positive for EBV-encoded RNA. Mediastinal lymph node biopsies also showed a

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Bell, Jonathan B. "A Chronic Lung Disorder Following Abdominal Pregnancy." Archives of Pediatrics & Adolescent Medicine 141, no. 10 (1987): 1111. http://dx.doi.org/10.1001/archpedi.1987.04460100089035.

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YADUKUMAR, LEKHA, POOJA KHARBANDA, and AJINKYA BURADKAR. "PULMONARY LANGERHANS HISTIOCYTOSIS: A RARE LUNG DISORDER." CHEST 164, no. 4 (2023): A4870—A4871. http://dx.doi.org/10.1016/j.chest.2023.07.3155.

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Colombat, Magali, Hervé Mal, Christiane Copie-Bergman, et al. "Primary cystic lung light chain deposition disease: a clinicopathologic entity derived from unmutated B cells with a stereotyped IGHV4-34/IGKV1 receptor." Blood 112, no. 5 (2008): 2004–12. http://dx.doi.org/10.1182/blood-2007-11-123596.

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Abstract We have recently described a new form of light chain deposition disease (LCDD) presenting as a severe cystic lung disorder requiring lung transplantation. There was no bone marrow plasma cell proliferation. Because of the absence of disease recurrence after bilateral lung transplantation and of serum-free light chain ratio normalization after the procedure, we hypothesized that monoclonal light chain synthesis occurred within the lung. The aim of this study was to look for the monoclonal B-cell component in 3 patients with cystic lung LCDD. Histologic examination of the explanted lung

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Juvet, Stephen C., David Hwang, Thomas K. Waddell, and Gregory P. Downey. "Rare Lung Diseases II: Pulmonary Alveolar Proteinosis." Canadian Respiratory Journal 15, no. 4 (2008): 203–10. http://dx.doi.org/10.1155/2008/528948.

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The present article is the second in a series on rare lung diseases. It focuses on pulmonary alveolar proteinosis (PAP), a disorder in which lipoproteinaceous material accumulates in the alveolar space. PAP was first described in 1958, and for many years the nature of the material accumulating in the lungs was unknown. Major insights into PAP have been made in the past decade, and these have led to the notion that PAP is an autoimmume disorder in which autoantibodies interfere with signalling through the granulocyte-macrophage colony-stimulating factor receptor, leading to macrophage and neutr

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Cheng, Wan-Li, Chih-Cheng Chang, Ching-Shan Luo, et al. "Targeting Lung–Gut Axis for Regulating Pollution Particle–Mediated Inflammation and Metabolic Disorders." Cells 12, no. 6 (2023): 901. http://dx.doi.org/10.3390/cells12060901.

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Cigarette smoking (CS) or ambient particulate matter (PM) exposure is a risk factor for metabolic disorders, such as insulin resistance (IR), increased plasma triglycerides, hyperglycemia, and diabetes mellitus (DM); it can also cause gut microbiota dysbiosis. In smokers with metabolic disorders, CS cessation decreases the risks of serious pulmonary events, inflammation, and metabolic disorder. This review included recent studies examining the mechanisms underlying the effects of CS and PM on gut microbiota dysbiosis and metabolic disorder development; one of the potential mechanisms is the di

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Mallea, Jorge M., Anna Kornafeld, Andras Khoor, and David B. Erasmus. "Lung Transplantation in a Patient with COPA Syndrome." Case Reports in Transplantation 2020 (April 1, 2020): 1–2. http://dx.doi.org/10.1155/2020/3624795.

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COPA syndrome is a newly discovered, rare genetic autoimmune disorder, which can affect the lungs, joints, and kidneys. It is difficult to recognize, and the survival benefit of lung transplantation for these patients is not yet known. We present a case of a 24-year-old woman who received bilateral lung transplant for COPA syndrome. At 15 months posttransplant, her pulmonary function is stable with no episodes of acute cellular- or antibody-mediated rejection and no evidence of disease recurrence.

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Abdulsaid, Ruaa, Azza Sajid, and Talib Kadhim Akar. "Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 32, no. 2 (2023): 25–32. http://dx.doi.org/10.31351/vol32iss2pp25-32.

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Background: Diabetes mellitus is a chronic metabolic disorder that may affect different organs including the lungs. Different studies have been published on the effects of diabetes mellitus on pulmonary function. A restrictive pattern of lung disorder was reported in some studies, whereas an obstructive pattern was suggested in others. The study aims to determine the impact of type 2 diabetes on pulmonary function tests (PFTs) and the type of respiratory disorder. Material and Methods: This observational study was conducted in Basrah City, Iraq. One hundred and eighty-two participants were enr

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Mizuguchi, Seiya, Kenichi Mizutani, Manabu Yamashita, Hiroshi Minato, and Sohsuke Yamada. "The potential usefulness of sputum cytology in the conclusive diagnosis of methotrexate-associated lymphoproliferative disorders: A case report." SAGE Open Medical Case Reports 7 (January 2019): 2050313X1983601. http://dx.doi.org/10.1177/2050313x19836017.

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Background: Methotrexate has been used as an anchor drug for the treatment of rheumatoid arthritis and is considered to be a cause of methotrexate-associated lymphoproliferative disorder. Spontaneous regression can occur after withdrawal of methotrexate and may be associated with Epstein–Barr virus positivity and non-diffuse large B cell lymphoma histological type. Methotrexate-associated lymphoproliferative disorders are often diagnosed pathologically by lung biopsy. To the best of our knowledge, there have been no studies on the cytological diagnosis of methotrexate-associated lymphoprolifer

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Carlos, Carpio, Gómez-Carrera Luis, and Álvarez-Sala Rodolfo. "Smoking and Other Interstitial Lung Diseases." ISRN Pulmonology 2011 (July 14, 2011): 1–7. http://dx.doi.org/10.5402/2011/876534.

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Cigarette smoking has been implicated in the development of some uncommon respiratory interstitial diseases. Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung diseases are characterized by a diffuse alveolar and peribronchiolar filling with macrophages, respectively. Pulmonary Langerhans' cell histiocytosis is a rare interstitial lung disorder characterized by the proliferation of Langerhans' cell forming interstitial infiltrates and nodules that could progress to cavitary nodules. The treatment of these disorders involves smoking cessation and some

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Li, Qianqian, Hui Liu, Chen Bai, et al. "A High-Calorie Diet Aggravates Lipopolysaccharide-Induced Pulmonary Inflammation in Juvenile Rats via Hypothalamic-Pituitary-Adrenal Axis-Related Pathways." International Journal of Molecular Sciences 26, no. 14 (2025): 6554. https://doi.org/10.3390/ijms26146554.

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The hypothalamic-pituitary-adrenal (HPA) axis plays an important regulatory role in inflammatory responses to systemic or local infection in the host. A high-calorie diet, which can aggravate pediatric pneumonia and delay recovery, is intimately associated with HPA axis disorder; however, its underlying mechanisms remain unknown. This study examined whether the mechanism by which a high-calorie diet aggravates pneumonia is related to HPA axis disorder. In this study, juvenile rats were fed a high-calorie diet and/or nebulized with lipopolysaccharide (LPS) for model construction. Our data shows

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Sakata, Yoshihiko, Kodai Kawamura, Kazuya Ichikado, and Masakazu Yoshioka. "A Case of Orbital Metastasis as Disease Progression of Anaplastic Lymphoma Kinase-Positive Lung Cancer Treated with Crizotinib." Case Reports in Oncology 8, no. 1 (2015): 21–24. http://dx.doi.org/10.1159/000371719.

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Orbital metastasis of lung cancer is rare. It often causes visual disorder. To date, there are only a few case reports. Crizotinib is an anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor that leads to responses in most patients with ALK-positive non-small-cell lung cancer. Visual disorder is one of the popular adverse events of crizotinib, but the symptom almost decreases over time. We report a case of orbital metastasis as the disease progression of ALK-positive lung cancer treated with crizotinib. It should be kept in mind that orbital metastasis can be the disease progression of lu

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Nishida, Chinatsu, Hiroto Izumi, Taisuke Tomonaga, et al. "Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation." International Journal of Molecular Sciences 23, no. 18 (2022): 10345. http://dx.doi.org/10.3390/ijms231810345.

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Background: We conducted intratracheal instillations of different molecular weights of polyacrylic acid (PAA) into rats in order to examine what kinds of physicochemical characteristics of acrylic acid-based polymer affect responses in the lung. Methods: F344 rats were intratracheally exposed to a high molecular weight (HMW) of 598 thousand g/mol or a low molecular weight (LMW) of 30.9 thousand g/mol PAA at low and high doses. Rats were sacrificed at 3 days, 1 week, 1 month, 3 months and 6 months post exposure. Results: HMW PAA caused persistent increases in neutrophil influx, cytokine-induced

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Strelnikova, Valeria A., Dmitry Yu Ovsyannikov, Olga B. Kondakova, et al. "NKX2-1-conditioned disorder — «brain–lung–thyroid» syndrome: results of a multicenter study." L.O. Badalyan Neurological Journal 5, no. 1 (2024): 14–28. http://dx.doi.org/10.46563/2686-8997-2024-5-1-14-28.

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Introduction. Brain–lung–thyroid syndrome (BLTS, choreoathetosis and congenital hypothyroidism with or without pulmonary dysfunction) is an autosomal dominant disorder associated with mutations of the NKX2-1 gene. A triad of symptoms from three organs (brain, lungs, thyroid gland) is manifested in 50% of patients, in other cases there is an incomplete phenotype of the disease. The most common manifestations are neurological. The aim of the study was to provide genetic, clinical, laboratory, and instrumental characteristics in BLTS patients with a clinical and morphological assessment of the ph

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Ra, Seung Won, Soyeoun Lim, Hee jeong Cha, and Sunyoung Kim. "A Case of Late-Onset Neuromyelitis Optica Spectrum Disorder Associated With Cryptogenic Organizing Pneumonia." Clinical Medicine Insights: Case Reports 15 (January 2022): 117954762211005. http://dx.doi.org/10.1177/11795476221100598.

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Introduction: Systemic diseases can be found in neuromyelitis optica spectrum disorder (NMOSD) as a co-existing disease with paraneoplastic syndrome, sarcoidosis, or connective tissue disease. Cryptogenic organizing pneumonia (COP) in NMOSD with no evidence of these systemic disorders has rarely been reported. Case presentation: We present a 75-year-old patient who showed multifocal longitudinally extensive transverse myelitis and bilateral lung lesions that was seropositive for aquaporin-4 (AQP4) antibody. The patient initially presented with chronic cough, myalgia, and severe bilateral trunc

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Sato, Hiroki, Kiyoaki Tsukahara, Isaku Okamoto, et al. "Interstitial Lung Disease Associated With Cetuximab in Patients With Head and Neck Carcinoma: A Single-Institution Experience in Japan." International Surgery 103, no. 11-12 (2019): 528–33. http://dx.doi.org/10.9738/intsurg-d-16-00256.1.

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Objective: This study retrospectively analyzed the risk of interstitial lung disease with cetuximab using risk factors known to be associated with interstitial lung disease during administration of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI). Summary of background data: Cetuximab is an inhibitor of EGFR commonly used for advanced squamous cell carcinoma of the head and neck. Interstitial lung disease is a rare but serious adverse event of cetuximab. EGFR-TKIs are molecularly targeted drugs resembling cetuximab and show increased risk of interstitial lung disease ass

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Panda, Rajesh, Saurabh Saigal, Rajnish Joshi, et al. "Accuracy of Critical Care Ultrasonography Plus Arterial Blood Gas Analysis Based Algorithm in Diagnosing Aetiology of Acute Respiratory Failure." Journal of Critical Care Medicine 9, no. 1 (2023): 20–29. http://dx.doi.org/10.2478/jccm-2023-0006.

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Abstract Introduction Lung ultrasound when used in isolation, usually misses out metabolic causes of dyspnoea and differentiating acute exacerbation of COPD from pneumonia and pulmonary embolism is difficult, hence we thought of combining critical care ultrasonography (CCUS) with arterial blood gas analysis (ABG). Aim of the study The objective of this study was to estimate accuracy of Critical Care Ultrasonography (CCUS) plus Arterial blood gas (ABG) based algorithm in diagnosing aetiology of dyspnoea. Accuracy of traditional Chest X-ray (CxR) based algorithm was also validated in the followi

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