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Journal articles on the topic 'Luxus <Motiv>'

Author: Grafiati

Published: 26 July 2024

Last updated: 31 July 2025

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1

Ulum, Bakhrul. "ETNOMATEMATIKA PASURUAN: EKSPLORASI GEOMETRI UNTUK SEKOLAH DASAR PADA MOTIF BATIK PASEDAHAN SUROPATI." Jurnal Review Pendidikan Dasar : Jurnal Kajian Pendidikan dan Hasil Penelitian 4, no. 2 (2018): 686. http://dx.doi.org/10.26740/jrpd.v4n2.p686-696.

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ABSTRACTThis research aims to explore and describe the ethnomathematics on Pasuruan society from the concept of geometry for elementary school on the Pasedahan Suropati batik motive, the philosophical meaning of it, and the alternative usage in teaching geometry in primary school. This research is a qualitative research with ethnographic approach, in wich the technique of collecting a literature study, observation, interviews, fields note, and documentation. Based on the data collecting, there are 6 kinds of Pasedahan Suropati batik in Pasuruan, they are Suruh Leaves motive, Podang Bird motive

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Muslimov, Ilham A., Valerio Berardi, Stacy Stephenson, Ellen M. Ginzler, John G. Hanly, and Henri Tiedge. "Autoimmune RNA dysregulation and seizures: therapeutic prospects in neuropsychiatric lupus." Life Science Alliance 5, no. 12 (2022): e202201496. http://dx.doi.org/10.26508/lsa.202201496.

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Lupus autoimmunity frequently presents with neuropsychiatric manifestations, but underlying etiology remains poorly understood. Human brain cytoplasmic 200 RNA (BC200 RNA) is a translational regulator in neuronal synapto-dendritic domains. Here, we show that a BC200 guanosine-adenosine dendritic transport motif is recognized by autoantibodies from a subset of neuropsychiatric lupus patients. These autoantibodies impact BC200 functionality by quasi irreversibly displacing two RNA transport factors from the guanosine-adenosine transport motif. Such anti-BC autoantibodies, which can gain access t

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Esser, Ruth L., Carolin Brück, Jan Thiele, et al. "Truncated isoforms of GPSM2 containing the GoLoco motif region promote CD4⁺ T-cell migration in SLE." Lupus Science & Medicine 9, no. 1 (2022): e000742. http://dx.doi.org/10.1136/lupus-2022-000742.

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ObjectiveSLE is an autoimmune disease with a complex pathogenesis. T-cell infiltration into organs contributes to inflammation and organ damage in SLE. Recently, G-protein signalling modulator 2 (GPSM2) has been shown to be implicated in T-cell migration.MethodsWe analysed the expression levels of GPSM2 and of a truncated isoform of GPSM2 containing the GoLoco motif region in CD4+ T cells from patients with SLE and from healthy individuals by western blot. In a next step, we studied the role of the truncated GPSM2 isoform using a CD4+ T-cell migration assay.ResultsOur experiments revealed comp

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Amanda, Braga Matos, Cardoso De Moraes Fracalossi Rafaela, Marques Das Mercês Thacyanne, and Souza Vieira Dallacqua Deusilene. "LÚPUS ERITEMATOSO SISTÊMICO: ASPECTOS CLÍNICOS-LABORATORIAIS E TRATAMENTO NA INFÂNCIA." Revistaft 28, no. 135 (2024): 10. https://doi.org/10.5281/zenodo.11569510.

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O lúpus eritematoso sistêmico (LES) é uma doença autoimune multissistêmica. É mais comum em mulheres, e em crianças abaixo de 10 anos o diagnóstico é raro. Os sintomas de LES são fortes em adultos, em crianças são bem mais agressivos. Sabe-se da dificuldade das crianças em sua adaptação pós diagnóstico, pois seu desenvolvimento é regredido. O LES pode afetar articulações, pele, rins, células sanguíneas, cérebro, coração e p

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LEE, HUI-TING, YU-MING SHIAO, TSAI-HUNG WU, et al. "Serum BLC/CXCL13 Concentrations and Renal Expression of CXCL13/CXCR5 in Patients with Systemic Lupus Erythematosus and Lupus Nephritis." Journal of Rheumatology 37, no. 1 (2009): 45–52. http://dx.doi.org/10.3899/jrheum.090450.

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Objective.Systemic lupus erythematosus (SLE) is a prototype of systemic autoimmune disease in which cytokines such as B lymphocyte chemoattractant (BLC, or CXC motif ligand 13, CXCL13) may play important roles in pathogenesis. We investigated the implications of CXCL13 in SLE and lupus nephritis.Methods.Serum samples from 425 patients with SLE and 106 healthy control individuals were analyzed for the concentration of CXCL13 by ELISA. Tissue expression of CXCL13 and its corresponding receptor CXCR5 were observed in lupus kidney. The CXCR5-bearing B cells in SLE patients were analyzed by flow cy

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Ledi, Fixaris, Benediktus Kusmanto, and Denik Agustito. "Identifikasi Etnomatematika pada Motif Kain Tenun Sumba Barat." UNION: Jurnal Ilmiah Pendidikan Matematika 8, no. 1 (2020): 87. http://dx.doi.org/10.30738/union.v8i1.5338.

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Tujuan penelitian ini adalah untuk mengidentifikasikan etnomatematika yang ada pada motif kain tenun Sumba Barat. Penelitian ini termasuk jenis penelitian deskriptif kualitatif dengan pendekatan etnografi. Data dalam penelitian ini adalah aktivitas etnomatematika pada kain tenun Sumba Barat yang diperoleh dari data pustaka dan data lisan. Teknik pengumpulan data pada penelitian ini menggunakan wawancara jarak jauh dan dokumentasi serta vidio. Teknik analisis data dilakukan terhadap data kualitatif (motif-motif yang ditemukan pada kain tenun Sumba Barat). Hasil penelitian di analisis dengan men

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Rahadi, Panji Firman, Oki Adityawan, Warsa Suarsa, and Dion Eko Valentino. "PERANCANGAN MOTIF KONTEMPORER KAIN SARUNG SEBAGAI TREND MODE PADA URBAN STYLE." Wacadesain 3, no. 1 (2022): 1–9. http://dx.doi.org/10.51977/wacadesain.v3i1.733.

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KaKain Sarung diakui merupakan salah satu identitas bangsa Indonesia, terbukti penggunaan kain Sarung hingga kini masih lestari digunakan oleh masyarakat Nusantara. Memiliki berbagai macam motif yang berbeda-beda dari setiap daerah di Indonesia, salah satunya motif Madras yang hingga kini masih mendominasi pada kain Sarung di Indonesia. Terpaku dengan identiknya motif Madras saat ini, diperlukan strategi untuk menghadapi trend-trend baru di masa yang akan datang, sehingga kelestarian kain sarung tidak tergores oleh perkembangan zaman. Inovasi perlu dilakukan karena Semakin berkembangnya motif

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Mehta, Pankti, Pratibha Singh, and Amita Aggarwal. "Serum and urinary galectin-9 and C-X-C motif chemokine ligand 10." Lupus 31, no. 4 (2022): 482–87. http://dx.doi.org/10.1177/09612033221082907.

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Background Systemic lupus erythematosus (SLE) is characterized by a type I interferon (IFN) signature, and traditional methods for its measurement like gene expression analysis are cumbersome for routine use. Thus, we aimed to study galectin-9 as a biomarker and compared it with a validated marker, C-X-C motifchemokine ligand 10(CXCL-10). Methods Ninety-seven patients with SLE (26 years; 89 females) were included and stratified based on renal involvement and activity into - active (SLEDAI > 4) renal (35), active non-renal (32) and inactive renal subgroups (30) along with 20 healthy controls

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Ochoa Garcia, Monica Elizabeth, and Carlos Altamirano Vergara. "Lupus eritematoso sistémico en pediatría, factores de mal pronostico." Medicina 20, no. 1 (2019): 27–32. http://dx.doi.org/10.23878/medicina.v20i1.641.

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El lupus eritematoso sistémico es una enfermedad autoinmunitaria que puede debutar con un espectro clínico de presentación muy amplio. Al ser una enfermedad potencialmente mortal es necesario un conocimiento exhaustivo del tema. En ocasiones puede debutar con manifestaciones neurológicas, compromiso renal, entre otras, las cuales son predictores de mal pronóstico. Un 15-20% de los pacientes desarrolla la enfermedad durante la edad pediátrica; por este motivo se presenta un caso de un paciente pediátrico con diagnóstico de lupus eritematoso sistémico y factores de mal pronóstico. En este artícu

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Nasiah, Nasiah, and Toni Toni. "Eksplorasi Etnomatematika pada Sarung Tenun Samarinda di Rumah Tenun Rahma Dina Samarinda Seberang." Borneo Journal of Science and Mathematics Education 4, no. 2 (2024): 67–76. https://doi.org/10.21093/bjsme.v4i2.8727.

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Etnomatematika merupakan pembelajaran matematika yang dikaitkan dengan budaya. Tujuan dari penelitian ini adalah untuk mengeksplorasi konsep matematika pada Sarung Tenun Samarinda dan menjadi media alternatif dalam pembelajaran matematika. Dalam pembelajaran matematika di sekolah, pada materi geometri bisa dikaitkan dengan budaya yang ada, seperti pada sarung tenun samarinda yang motif-motifnya berbentuk bangun datar geometri. Dengan ini matematika terasa lebih nyata di kehidupan. Objek dari penelitian ini adalah Sarung Tenun Samarinda. Teknik pengumpulan data dilaksanakan dengan wawancara, do

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Lee, Yeon Su, Jin Seok Woo, JooYeon Jhun, et al. "SARS-CoV-2 spike aggravates lupus nephritis and lung fibrosis in systemic lupus erythematosus." Lupus Science & Medicine 11, no. 2 (2024): e001104. http://dx.doi.org/10.1136/lupus-2023-001104.

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Objective COVID-19 induces the development of autoimmune diseases, including SLE, which are characterised by inflammation, autoantibodies and thrombosis. However, the effects of COVID-19 on SLE remain unclear. Methods We investigated the effects of COVID-19 on SLE development and progression in three animal models. Plasmids encoding SARS-CoV-2 spike protein and ACE2 receptor were injected into R848-induced BALB/C lupus mice, R848-induced IL-1 receptor antagonist knockout (KO) lupus mice and MRL/lpr mice. Serum levels of albumin and autoantibodies, lymphocyte phenotypes and tissue histology wer

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Chen, Xiangjun, Xiaolin Sun, Wei Yang, et al. "An autoimmune disease variant of IgG1 modulates B cell activation and differentiation." Science 362, no. 6415 (2018): 700–705. http://dx.doi.org/10.1126/science.aap9310.

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The maintenance of autoreactive B cells in a quiescent state is crucial for preventing autoimmunity. Here we identify a variant of human immunoglobulin G1 (IgG1) with a Gly396→Arg substitution (hIgG1-G396R), which positively correlates with systemic lupus erythematosus. In induced lupus models, murine homolog Gly390→Arg (G390R) knockin mice generate excessive numbers of plasma cells, leading to a burst of broad-spectrum autoantibodies. This enhanced production of antibodies is also observed in hapten-immunized G390R mice, as well as in influenza-vaccinated human G396R homozygous carriers. This

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Patappa, Maghfira Maulani. "STUDI TENTANG PEMBUATAN DESAIN MOTIF BATIKLONTARA.COM." JURNAL IMAJINASI 3, no. 2 (2019): 36. http://dx.doi.org/10.26858/i.v3i2.13038.

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Penelitian ini bertujuan untuk mengetahui proses pembuatan desain motif dan penerapan unsur dan prinsip desain dalam pembuatan desain motif Batiklontara.com. Penelitian ini adalah penelitian deskriptif kualitatif tentang pembuatan desain motif Batiklontara.com. Teknik pengumpulan data yang digunakan adalah observasi, wawancara, dan dokumentasi. Penelitian ini berfokus pada proses pembuatan desain Batiklontara.com dengan memperhatikan unsur dan prinsip desain dalam proses pembuatannya, dengan memperoleh informasi dari Rachmat Nurfansyah, pemilik Batiklontara.com, dan desainer Batiklontara.com,

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Hernández Torres, Yessenia, Iris Paola García Herrera, and Luis Alberto Aparicio Vera. "Lupus eritematoso sistémico masculino, reporte de características clínicas y serológicas en población pediátrica Mexicana." Revista Paraguaya de Reumatología 9, no. 1 (2023): 10–15. http://dx.doi.org/10.18004/rpr/2023.09.01.10.

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El lupus eritematoso sistémico es una enfermedad autoinmune compleja con numerosas manifestaciones clínicas y de laboratorio. La incidencia aumenta notablemente en la mujer. El motivo del predominio en el género femenino aún está en estudio. Se ha descrito en algunos estudios que el diagnóstico de lupus en población pediátrica masculina puede tener peor pronóstico con afectación más severa. Métodos: En este trabajo se describen las características clínicas y serológicas de una población pediátrica mexicana en un hospital mexicano de tercer nivel. Resultados: El trastorno renal fue más alto que

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Tong, Xinya, Wenwen Chen, Lele Ye, et al. "5-Hydroxymethylcytosine in circulating cell-free DNA as a potential diagnostic biomarker for SLE." Lupus Science & Medicine 11, no. 2 (2024): e001286. http://dx.doi.org/10.1136/lupus-2024-001286.

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BackgroundSLE is a complex autoimmune disease with heterogeneous manifestations and unpredictable outcomes. Early diagnosis is challenging due to non-specific symptoms, and current treatments only manage symptoms. Epigenetic alternations, including 5-Hydroxymethylome (5hmC) modifications, are important contributors to SLE pathogenesis. However, the 5hmC modification status in circulating cell-free DNA (cfDNA) of patients with SLE remains largely unexplored. We investigated the distribution of 5hmC in cfDNA of patients with SLE and healthy controls (HCs), and explored its potential as an SLE di

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Soleh, Moh Qhoerudin, and Kuntadi Wasi Darmojo. "Burung Enggang Badak Sebagai Motif Hias pada Bilah Keris Tinatah." Ornamen 21, no. 1 (2024): 128–39. http://dx.doi.org/10.33153/ornamen.v21i1.6061.

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Burung Enggang merupakan burung yang sangat penting dalam kehidupan suku Dayak. Unsur terpenting dalam organisasi suku Dayak adalah hutan yang diperlambangkan dengan Burung Enggang yang lebih lanjut melambangkan sesuatu yang “lebih tinggi”. Jenis enggang yang dihormati yaitu enggang badak dikarenakan satwa itu berhubungan dengan simbol ritual Dayak Iban, yaitu gawai kenyalang. Burung Enggang Badak dalam artikel ini dijadikan sumber ide penciptaan dhapur keris baru yang diterapkan pada bentuk keris lurus dengan menerapkan motif tinatah Burung Enggang pada bilahnya. Dipilihnya Burung Enggang ini

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Su, Yu-Jih, Fu-An Li, Jim Jinn-Chyuan Sheu, et al. "A Study on MDA5 Signaling in Splenic B Cells from an Imiquimod-Induced Lupus Mouse Model with Proteomics." Cells 11, no. 21 (2022): 3350. http://dx.doi.org/10.3390/cells11213350.

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Introduction: Several environmental stimuli may influence lupus, particularly viral infections. In this study, we used an imiquimod-induced lupus mouse model focused on the TLR7 pathway and proteomics analysis to determine the specific pathway related to viral infection and the related protein expressions in splenic B cells to obtain insight into B-cell responses to viral infection in the lupus model. Materials and Methods: We treated FVB/N wild-type mice with imiquimod for 8 weeks to induce lupus symptoms and signs, retrieved splenocytes, selected B cells, and conducted the proteomic analysis

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Journal, Administrator. "PEWARNA ALAMI JARENANG PADA BAMBU SEBAGAI BAHAN MENYILIP KERAJINAN ROTAN (Natural Colouration of Jarenang to Bamboo as Plaited Rattan Handicraft)." HUTAN TROPIKA 13, no. 2 (2019): 114–20. http://dx.doi.org/10.36873/jht.v13i2.300.

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ABSTRAKKerajinan rotan merupakan salah satu produk unggulan kota Palangka Raya. Umumnya produkyang dihasilkan ada yang bermotif dan adanya yang tidak. Permasalahan yang dihadapi Perajinadalah hanya mampu menghasilkan anyaman tanpa motif (polos), sedangkan konsumen banyakmenginginkan produk yang dihasilkan mempunyai motif yang menampilkan dan menonjolkankerajinan khas suku dayak Kalimantan Tengah Mitra sasaran adalah masyarakat produktifsecara ekonomi, yakni kelompok usaha mikro Jawet Bawi Rawi. Unsur pendampingan yangdiusulkan bagi perajin adalah pelatihan dan diversifikasi pemberian motif den

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Mohan, C., S. Adams, V. Stanik, and S. K. Datta. "Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus." Journal of Experimental Medicine 177, no. 5 (1993): 1367–81. http://dx.doi.org/10.1084/jem.177.5.1367.

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Only a fraction (12%) of 268 "autoreactive" T cell clones derived from lupus-prone mice can selectively induce the production of pathogenic anti-DNA autoantibodies in vitro and accelerate the development of lupus nephritis when transferred in vivo. The CDR3 loops of T cell receptor beta chains expressed by these pathogenic T helper (Th) clones contain a recurrent motif of anionic residues suggesting that they are selected by autoantigens with cationic residues. Herein, we found that approximately 50% of these pathogenic Th clones were specific for nucleosomal antigens, but none of them respond

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Ardianti, Evi, Ali Hadara, and Irawaty Irawaty. "PELESTARIAN SARUNG TENUN PADA MASYARAKAT DI DESA BALASUNA KECAMATAN KALEDUPA KABUPATEN WAKATOBI." Jurnal Penelitian Pendidikan Sejarah UHO 8, no. 2 (2023): 102–11. https://doi.org/10.36709/jpps.v8i2.53.

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Abstrak: Tujuan Peneltian ini adalah : 1) Untuk menjelaskan proses pembuatan sarung tenun tradisinonal di Desa Balasuna Kecamatan Kaledupa Kabupaten Wakatobi. 2) Untuk menjelaskan motif dan makna simbol sarung tenun pada masyarakat di Desa Balasuna Kecamatan Kaledupa. 3) Untuk Mendeskripsikan upaya pelestarian budaya sarung tenun tradisional pada masyarakat di Desa Balasuna Kecamatan Kaledupa. Penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif. Penelitian deskriptif kualitatif ini dengan tahapan-tahapan sebagai berikut: 1) teknik pengumpulan data melalui wawancara, obs

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Arbuckle, Melissa R., Alyssa R. Schilling, John B. Harley, and Judith A. James. "A Limited Lupus Anti-Spliceosomal Response Targets a Cross-Reactive, Proline-Rich Motif." Journal of Autoimmunity 11, no. 5 (1998): 431–38. http://dx.doi.org/10.1006/jaut.1998.0227.

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Chen, Jie, Lu Liu, Min Liu та ін. "Knockdown of TRIM22 regulates the expression of NF-κB/NLRP3 and alleviates inflammation and renal injury in mice withlupus nephritis". Allergologia et Immunopathologia 52, № 3 (2025): 98–105. https://doi.org/10.15586/aei.v53i3.1313.

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Lupus nephritis (LN) is a common and clinically challenging complication of the systemic lupus erythematosus (SLE), but effective treatments remain imperative. Tripartite Motif Containing 22 (TRIM22) is a protein involved in various cellular processes, such as cell growth and inflam-matory responses. However, the role and mechanism of TRIM22 in LN are still unclear. The aim of this study was to reveal the role of TRIM22 in LN and uncover the potential mechanisms. We discovered that TRIM22 is notably upregulated in renal tissues from patients with LN. Functionally, the knockdown of TRIM22 in lu

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Jin, Xuexiao, and Linrong Lu. "Anti-CD19 CAR-T cell therapy for Systemic Lupus Erythematosus in a mouse disease model." Journal of Immunology 204, no. 1_Supplement (2020): 238.3. http://dx.doi.org/10.4049/jimmunol.204.supp.238.3.

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Abstract Dysregulated B cell activation plays pivotal roles in systemic lupus erythematosus (SLE), which makes B-cell-depletion a potential strategy for SLE treatment. The clinical success of anti-CD19 chimeric antigen receptor (CAR) T cells in treating B-cell malignancies has attracted the attention of researchers. In this study, we aimed to investigate the feasibility of applying anti-CD19 CAR-T cell therapy into SLE treatment in a mouse disease model. We have constructed murine anti-CD19 CARs with either CD28 or 4-1BB as the intracellular costimulatory motif and evaluated the therapeutic fu

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Suhardi, Yusuf, Muhammad Ramaditya, Arya Darmawan, Meita Pragiwani, and Nursanita Nasution. "Motivasi Menuju Ujian Sekolah dan Ujian Masuk Universitas Jakarta." PROGRESIF: Jurnal Pengabdian Komunitas Pendidikan 3, no. 1 (2023): 65–74. http://dx.doi.org/10.36406/progresif.v3i1.941.

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Tujuan pengabdian kepada masyarakat (PKM) Dosen STEI ini adalah agar siswa Kelas XII SMAN 21 siap menghadapi ujian sekolah dan siap untuk melajutkan ke universitas di Jakarta. Metode PKM diselenggarakan dengan cara ceramah dan tanya jawab. Motif diartikan sebagai kekuatan yang terdapat dalam diri seseorang yang mendorong untuk berbuat. Motif tidak berdiri sendiri, tetapi saling berkaitan dengan faktor-faktor lain, baik faktor eksternal maupun faktor internal. Motivasi sebagai kegiatan memberikan dorongan kepada seseorang atau diri sendiri untuk mengambil suatu tindakan yang dikehendaki oleh ya

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Ramantani, Georgia, Martin Häusler, Pascal Niggemann, et al. "Aicardi-Goutières Syndrome and Systemic Lupus Erythematosus (SLE) in a 12-Year-Old Boy With SAMHD1 Mutations." Journal of Child Neurology 26, no. 11 (2011): 1425–28. http://dx.doi.org/10.1177/0883073811408310.

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Aicardi-Goutières syndrome is an early-onset encephalopathy with a presumed immune pathogenesis caused by inherited defects in nucleic acid metabolism. The clinical picture resembles a congenital viral infection despite negative investigations for common viruses. In addition to leukoencephalopathy with calcifications of basal ganglia, patients show increased levels of the antiviral cytokine interferon-α in cerebrospinal fluid. We report on a 12-year-old boy with Aicardi-Goutières syndrome and systemic lupus erythematosus (SLE) due to mutations in the SAMHD1 (sterile alpha motif domain and HD d

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Widaratna, Praja Adytia, Gede Eka Harsana Koriawan, and Langen Bronto Sutrisno. "ASIMILASI MOTIF JAWA DAN MADURA PADA RUMAH ADAT TABING TONGKOK DI SITUBONDO JAWA TIMUR." Jurnal Pendidikan Seni Rupa Undiksha 13, no. 1 (2023): 35–45. http://dx.doi.org/10.23887/jjpsp.v13i1.60970.

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Penelitian ini bertujuan untuk menganalisis Asimilasi Motif Jawa dan Madura pada Rumah Adat Tabing Tongkok di Situbondo Jawa Timur. Tabing Tongkok merupakan ciri khas dari rumah adat Joglo Situbondo. Rumah adat tradisional yang saat ini kian ditinggalkan dan kehilangan nilai filosofinya. Subjek penelitian ini adalah pemilik rumah adat tabing tongkok dan tukang yang membuat rumah adat tabing tongkok. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Pengumpulan data dilakukan menggunakan metode dokumentasi, wawancara dan kepustakaan. Dengan menggunakan analisis reduks

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Mistry, Pragnesh, Shuichiro Nakabo, Liam O’Neil, et al. "Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus." Proceedings of the National Academy of Sciences 116, no. 50 (2019): 25222–28. http://dx.doi.org/10.1073/pnas.1908576116.

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Neutrophil dysregulation is implicated in the pathogenesis of systemic lupus erythematosus (SLE). SLE is characterized by elevated levels of a pathogenic neutrophil subset known as low-density granulocytes (LDGs). The origin and phenotypic, functional, and pathogenic heterogeneity of LDGs remain to be systematically determined. Transcriptomics and epigenetic assessment of lupus LDGs, autologous normal-density neutrophils, and healthy control neutrophils was performed by bulk and single-cell RNA sequencing and assay for transposase-accessible chromatin sequencing. Functional readouts were compa

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Kaifang Liu, Yunfeng Liao, Pu Li, and Jing Shi. "Retrospective analysis of the clinical significance of Ro52/TRIM21 antibody and specific antinuclear antibody patterns by indirect immunofluorescence." Journal of the Pakistan Medical Association 74, no. 2 (2024): 236–42. http://dx.doi.org/10.47391/jpma.8027.

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Objectives: To determine the clinical significance of Ro52 protein/tripartite motif-containing 21 antibody and specific antinuclear antibody patterns using indirect immunofluorescence technique. Method: The retrospective study was conducted at the clinical laboratory of the First Affiliated Hospital of Chongqing Medical University, China, and comprised data from January 2017 to December 2021 of patients who underwent antinuclear antibody and anti-extractable nuclear antigen antibody detection. Inpatients with Ro52 antibody-positive status were taken as the cases, while anti-Ro52 negative patie

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Wulandari, I. Gusti Ayu Athina, and Anak Agung Gede Agung Parameswara. "Problematika UMKM Berbasis Budaya Lokal di Bali (Studi Kasus Pemasaran Produk UMKM Berbasis Budaya Lokal di Pesta Kesenian Bali)." Ekonomi dan Bisnis 6, no. 2 (2020): 101. http://dx.doi.org/10.35590/jeb.v6i2.1263.

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Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang mempengaruhi UMKM berbasis budaya lokal berpartisipasi dalam pameran kerajinan di Pesta Kesenian Bali. UMKM berbasis budaya lokal seharusnya memiliki peluang yang sama untuk mempromosikan produknya pada pameran tersebut, namun faktanya tidaklah demikian karena ada perlakuan “pilih kasih” yang membuat adanya ketidakmerataan peluang berpromosi. Hanya UMKM yang lulus seleksi dan memiliki kualifikasi skala produksi mapan yang bisa berpartisipasi. Oleh karenanya, mayoritas peserta pameran kerajinan adalah peserta lama yang telah

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Zulmaulida, Rahmy, and Edy Saputra. "KERAWANG GAYO DAN GEOMETRI." ALGORITMA: Journal of Mathematics Education 6, no. 1 (2024): 45–56. https://doi.org/10.15408/ajme.v6i1.40555.

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AbstractGayo cultural diversity and the development of geometry concepts as a branch of mathematics can be collaborated through ethnomathematics. This research aims to see and study Kerawang Gayo's work in geometry. This study uses a qualitative approach to ethnography. The research was carried out in the city of Takengon, with the subject of the study being Kerawang Gayo's carving. The instruments used are non-test instruments such as interviews and observation sheets. The data analysis technique in this study goes through several processes, namely: a) data collection; b) reduction; c) presen

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Rybakowska, Paulina, Nina Wolska, Arkadiusz Klopocki, et al. "Multiple TRIM proteins are targets of autoimmune response in lupus and Sjogren's syndrome. (HUM7P.308)." Journal of Immunology 192, no. 1_Supplement (2014): 184.17. http://dx.doi.org/10.4049/jimmunol.192.supp.184.17.

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Abstract TRIM21 belongs to the large family of tripartite motif containing proteins, and is often targeted by autoantibodies in lupus and Sjogren’s syndrome. Considering the significant protein domain homology between different TRIM proteins, we hypothesized that additional TRIM proteins are targets of autoimmunity. Based on the literature, in this study we investigated autoantibody responses to TRIM38. While 9% of lupus patients (n=149) had anti-TRIM38 antibodies, the incidence in Sjogren’s syndrome patients (n=150) was 12%, and in controls (n=50) it was 4%. With respect to TRIM21, the incide

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Gao, Jie, Lingling Wu, Siyang Wang, and Xiangmei Chen. "Role of Chemokine (C–X–C Motif) Ligand 10 (CXCL10) in Renal Diseases." Mediators of Inflammation 2020 (February 5, 2020): 1–16. http://dx.doi.org/10.1155/2020/6194864.

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Chemokine C–X–C ligand 10 (CXCL10), also known as interferon-γ-inducible protein 10 (IP-10), exerts biological function mainly through binding to its specific receptor, CXCR3. Studies have shown that renal resident mesangial cells, renal tubular epithelial cells, podocytes, endothelial cells, and infiltrating inflammatory cells express CXCL10 and CXCR3 under inflammatory conditions. In the last few years, strong experimental and clinical evidence has indicated that CXCL10 is involved in the development of renal diseases through the chemoattraction of inflammatory cells and facilitation of cell

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Zhu, Jane L., Jack C. O'Brien, Grant Barber, Ramesh Saxena, and Benjamin F. Chong. "Elevated serum levels of C-X-C motif chemokine ligand 10 can distinguish systemic lupus erythematosus patients from cutaneous lupus erythematosus patients." Journal of the American Academy of Dermatology 85, no. 4 (2021): 1051–54. http://dx.doi.org/10.1016/j.jaad.2021.04.032.

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Mao, C., G. E. Osman, S. Adams, and S. K. Datta. "T cell receptor alpha-chain repertoire of pathogenic autoantibody-inducing T cells in lupus mice." Journal of Immunology 152, no. 3 (1994): 1462–70. http://dx.doi.org/10.4049/jimmunol.152.3.1462.

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Abstract The production of pathogenic anti-DNA autoantibodies in mice with lupus nephritis is dependent on special autoimmune Th cells that can also transfer the disease into preautoimmune mice. In previous work, these pathogenic Th cells were cloned and their TCR beta-chains were sequenced to reveal a recurrent motif of anionic residues in their CDR3 loops. Accordingly, approximately half of the Th clones were found to be specific for nucleosomal Ag that contain cationic residues. Herein, we analyzed the TCR alpha-chain repertoire of 15 of these pathogenic Th clones and found them to be heter

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Lopez-Pedrera, C., M. Á. Aguirre-Zamorano, L. Muñoz-Barrera, et al. "POS0465 UNSUPERVISED CLUSTERING ANALYSIS OF THE SERUM PROTEOME IDENTIFIES SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS WITH DISTINCTIVE DISEASE SEVERITY AND LUPUS NEPHROPATHY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 486.2–487. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4467.

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BackgroundSystemic lupus erythematosus (SLE) is a remarkably heterogeneous autoimmune disease. Despite great efforts, our knowledge of serum protein patterns in severe SLE phenotypes is still limited.ObjectivesThis study investigated the serum proteomic profile of SLE, in order to identify relevant clinical patterns.MethodsProximity extension immunoassay (PEA, Olink) was used to assess the serum levels of one hundred and eighty-four inflammation and organ damage-related proteins in patients with SLE (n = 72) and age-matched healthy donors (HD) (n = 18). In parallel, an extensive clinical and a

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Szymczak, Maciej, Harald Heidecke, Marcelina Żabińska, et al. "The Influence of Anti-ETAR and Anti-CXCR3 Antibody Levels on the Course of Specific Glomerulonephritis Types." Journal of Clinical Medicine 13, no. 24 (2024): 7752. https://doi.org/10.3390/jcm13247752.

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Background: Anti-ETAR (endothelin A receptor) antibodies and anti-CXCR3 (C-X-C motif chemokine receptor 3) antibodies are types of non-HLA (human leukocyte antigens) antibodies that could have some influence on the course of glomerulonephritis. The authors aimed to study the influence of these antibodies’ levels on the course of specific glomerulonephritis types. Methods: We evaluated the anti-ETAR and anti-CXCR3 antibody levels in the serum of patients with membranous nephropathy (n = 18), focal and segmental glomerulosclerosis (FSGS) (n = 25), systemic lupus erythematosus (n = 17), IgA nephr

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., Ferizone, Endri Bagus Prastiyo, Alfi Husni, Rianto ., Desmayeti Arfa, and Veny Melisa Arindini. "Motivasi Pemuda Dalam Melanjutkan Perguruan Tinggi (Studi Pada Pemuda Yang Melanjutkan Studi Ke Perguruan tinggi Di Kampung Suka Jadi Desa Pangke Kabupaten Karimun)." Equilibrium: Jurnal Pendidikan 12, no. 2 (2024): 227–35. https://doi.org/10.26618/equilibrium.v12i2.14985.

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Penelitian ini dilakukan untuk mengetahui motivasi pemuda dalam melanjutkan perguruan tinggi di Kampung Suka Jadi Desa Pangke Kecamatan Meral Barat Kabupaten Karimun. Penelitian ini merupakan jenis penelitian deskriptif dengan pendekatan kualitatif, dan teknik pengumpulan data menggunakan observasi, wawancara dan dokumentasi. Populasi dalam penelitian ini adalah pemuda Kampung Suka Jadi yang baru lulus sekolah menengah di tahun 2022 yaitu sebanyak 28 jiwa, dengan menggunakan teknik pengambilan sampel yaitu purposive sampling, dan diperoleh kriteria sampel tersebut yaitu pemuda yang lulus SLTA/

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Kisbali, Tamás Péter. "“LUDUS NATURAE”: SHELLS AS SCULPTED MOTIFS IN ANCIENT GREEK ART." RSUH/RGGU Bulletin. "Literary Theory. Linguistics. Cultural Studies" Series 1 (2023): 155–68. http://dx.doi.org/10.28995/2686-7249-2023-1-155-168.

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In this article, I trace the various ways Ancient Greek artisans used seashell-motifs, and how they interpreted these natural forms in artistic contexts. The reason for the popularity of seashells lies in their visual and haptic variety, their wealth of association, and the device of something secret hidden under the hard outer shell. I examine three possible variants of the motif’s treatment in relief and volume: the shell-container as part of a vessel, the shell as an independent container, the shell as a sculpted motif on a vessel. Of particular interest are the vases where the integration

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Figueroa, Celeste, Marcelo Servin, Laura Silvana Aria Zaya, and María Eugenia Acosta de Hetter. "Características clínicas de pacientes con Lupus Eritematoso Sistémico internados del Hospital Nacional de Itauguá del año 2022 al 2024." Revista Paraguaya de Reumatología 11, no. 1 (2025): 10–15. https://doi.org/10.18004/rpr/2025.11.01.10.

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Introducción: : El lupus eritematoso sistémico (LES) puede llevar a complicaciones que requieran de hospitalización. Objetivo: Evaluar las características clínicas de pacientes con LES internados en el Hospital Nacional de Itauguá entre 2022 y 2024. Material y Método: Estudio observacional, descriptivo y retrospectivo. Se revisaron 97 fichas clínicas de pacientes adultos diagnosticados con LES, hospitalizados en el servicio de clínica médica. Se analizaron variables sociodemográficas, comorbilidades, motivos de ingreso, actividad de la enfermedad (SLEDAI), tratamiento y estancia hospitalaria.

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Monneaux, Fanny, Véronique Parietti, Jean-Paul Briand, and Sylviane Muller. "Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus." Arthritis Research & Therapy 9, no. 5 (2007): R111. http://dx.doi.org/10.1186/ar2317.

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Park, H. W., D. S. Kim, Y. Park, M. L. Cho, and S. K. Kwok. "LB0008 Novel pathogenetic mechanisms mediated by dysregulation of TRIM21-STING-type I interferon axis in lupus." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 204. http://dx.doi.org/10.1136/annrheumdis-2023-eular.7049.

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BackgroundTripartite motif-containing protein (TRIM) 21 is an E3 uniquitin-protein ligase, involved in the ubiquitin-dependent proteolysis pathway of various proteins including factors related to type I interferon pathways. Although the presence of autoantibodies against TRIM21 in various autoimmune diseases suggests potential pathogenetic roles, no studies have clarified its exact implications especially in lupus.ObjectivesWe aimed to elucidate the functions of TRIM21 in dysregulation of type I interferon signals in lupus.MethodsTo investigate effects of TRIM21 dysfunction in lupus pathogenes

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Bidayani, Endang, and Ahmad Fahrul Syarif. "PEMBERDAYAAN UNIT KEGIATAN MAHASISWA (UKM) UBB: EKSPLORASI KEINDAHAN BAWAH LAUT BANGKA BELITUNG MELALUI BATIK TULIS." Jurnal Pengabdian Kepada Masyarakat Universitas Bangka Belitung 5, no. 2 (2019): 24–28. http://dx.doi.org/10.33019/jpu.v5i2.744.

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Kegiatan IbM dilaksanakan di workshop UKM Batik Tulis Pinang Sirih Kelurahan Selindung Kecamatan Gabek Kota Pangkalpinang. Melalui program ini mahasiswa dapat memperoleh keterampilan membatik, sekaligus makin meningkatkan kecintaan mereka terhadap bahari dan budaya Indonesia. Kegiatan membatik ini diharapkan dapat memberikan keuntungan antara lain: 1) Menumbuhkan minat mahasiswa untuk melestarikan batik; 2) Meningkatkan keterampilan mahasiswa menghasilkan batik bermotif keindahan alam; 3) Membuka peluang usaha; dan 4) Menumbuhkan jiwa entrepreneur bagi mahasiswa. Luaran yang dihasilkan dari ke

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Beltran, Rafael. "La roda de sénia, divisa brodada al vestit de Morgana («Tirant lo Blanc»), i el rodet de molí com a divisa d’Alfons V de Portugal." Tirant: Butlletí informatiu i bibliogràfic de literatura de cavalleries, no. 27 (December 23, 2024): 189–208. https://doi.org/10.7203/tirant.27.30119.

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L’episodi de l’arribada de la nau negra amb Morgana, la germana d’Artús de Bretanya, que acudeix a alliberar-lo de la presó, té lloc al Tirant lo Blanc i ha sigut estudiat des de diferents punts de vista. Morgana duu brodat al seu luxós vestit una estranya divisa de rodes de sénia, amb cadúfols foradats, un motiu que no sembla atzarós, atesa la tradició i rellevància simbòlica del seu personatge i el rerefons polític d’aquests capítols. Tractem de vincular aquestes «rodes de sénia» amb els símbols d’altres divises de sénies, que trobem en les cases reials peninsulars de l’època, sobre tot en l

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Brizuela Fernández, Romina Magalí, Delma Paola Morales Lugo, Fernando Rubén Moreno Argüello, Julio Reinaldo Martinez Ayala, and Enrique García Bello. "Infecciones más frecuentes en pacientes con Lupus Eritematoso Sistémico internados en el Servicio de Clínica Médica del Hospital Nacional." Revista del Nacional (Itauguá) 16, no. 1 (2024): 60–68. http://dx.doi.org/10.18004/rdn2024.ene.01.060.068.

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Introducción: el lupus eritematoso sistémico (LES) se conoce como una enfermedad autoinmune multisistémica, cuya causa es desconocida, se caracteriza por la presencia de complejos inmunes y autoanticuerpos. En series internacionales se describe una presentación de procesos infecciosos en estos pacientes hasta en un 75 % de los casos, las infecciones ocurren tanto al inicio de la enfermedad como en etapas tardías, y son causa directa de muerte en 30 % a 60 % de los casos y motivo de hospitalización hasta de 30 %. Objetivos: determinar los procesos infecciosos más frecuentes en pacientes con lup

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Ramírez Calderón, Santiago, Israel David Villalba Fonseca, Daniela Mingan Estrada, Larry Mansur Meneses Rueda, Libardo Antonio Caballero Morales, and Daynela Margarita Navarro Barraza. "Lupus en el Embarazo: ¿Qué hay de Nuevo?" Ciencia Latina Revista Científica Multidisciplinar 8, no. 6 (2024): 1972–85. https://doi.org/10.37811/cl_rcm.v8i6.14957.

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El lupus eritematoso sistémico (LES) es una enfermedad autoinmune crónica, caracterizada por una respuesta inmunitaria anómala que afecta diversos órganos y sistemas del cuerpo, siendo más prevalente en mujeres durante su etapa fértil. Esta enfermedad puede complicar significativamente el embarazo, con riesgos para la salud materna y fetal, incluyendo condiciones graves como taponamiento cardíaco, neumonitis, preeclampsia, trombosis, e incluso muerte fetal. Estas complicaciones son parte de la razón por la cual el diagnóstico y manejo del LES durante el embarazo representan un desafío consider

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Bruckner, Shane, Braden Zeno, Hannah Bulgart, et al. "ANTI-TRIM72 Autoantibodies IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS AND A LUPUS MOUSE MODEL WITH MYOCARDITIS COMPROMISE MEMBRANE REPAIR IN CARDIOMYOCYTES POTENTIALLY CONTRIBUTING TO CARDIOVASCULAR DISEASE PROGRESSION." Journal of Rheumatology 52, Suppl 1 (2025): 83.2–84. https://doi.org/10.3899/jrheum.2025-0390.pv008.

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PV008 / #647Poster Topic:AS02 - Animal ModelsBackground/PurposeSystemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that causes inflammation in many of the body’s tissues, including the heart. Recent studies attribute almost 50% of mortality in lupus patients to cardiovascular (CV) disease after the first 10 years. A significant prevalence of myocardial inflammation in SLE patients has been recognized across the age spectrum confirming the presence of myocarditis in up to 40% of lupus patients. Understanding the pathogenic mechanisms that drive CV disease in SLE patients is essen

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Adriani, Adriani, and Nova Fitriani. "MOTIF DAN MAKNA MOTIF TENUN ULOS BATAK ANGKOLA DI KABUPATEN TAPANULI SELATAN." Gorga : Jurnal Seni Rupa 12, no. 2 (2023): 302. http://dx.doi.org/10.24114/gr.v12i2.49593.

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The current problem is that the Angkola Batak Ulos weaving is not widely known to the public, because the types of Ulos in North Sumatra are very diverse. This research was conducted to describe the shape of the motifs, the meaning of the motifs and the weaving technique of Angkola Batak Ulos in South Tapanuli Regency. The research method used is descriptive qualitative with data types in the form of primary data and secondary data. Collecting data in this study using observation techniques, interviews and documentation. The results of the research show that the Ulos Batak Angkola weaving moti

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Oikawa, Daisuke, Kouhei Shimizu, and Fuminori Tokunaga. "Pleiotropic Roles of a KEAP1-Associated Deubiquitinase, OTUD1." Antioxidants 12, no. 2 (2023): 350. http://dx.doi.org/10.3390/antiox12020350.

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Protein ubiquitination, which is catalyzed by ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin ligases, is a crucial post-translational modification to regulate numerous cellular functions in a spatio–temporal-specific manner. The human genome encodes ~100 deubiquitinating enzymes (DUBs), which antagonistically regulate the ubiquitin system. OTUD1, an ovarian tumor protease (OTU) family DUB, has an N-terminal-disordered alanine-, proline-, glycine-rich region (APGR), a catalytic OTU domain, and a ubiquitin-interacting motif (UIM). OTUD1 preferentially hydrolyzes lysin

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Ble, Alessandro, Marta Mosca, Giorgio Di Loreto, et al. "Antiproteinuric Effect of Chemokine C-C Motif Ligand 2 Inhibition in Subjects with Acute Proliferative Lupus Nephritis." American Journal of Nephrology 34, no. 4 (2011): 367–72. http://dx.doi.org/10.1159/000330685.

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Lakamp, Amanda S., and Michel M. Ouellette. "A ssDNA Aptamer That Blocks the Function of the Anti-FLAG M2 Antibody." Journal of Nucleic Acids 2011 (2011): 1–11. http://dx.doi.org/10.4061/2011/720798.

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Using SELEX (systematic evolution of ligands by exponential enrichment), we serendipitously discovered a ssDNA aptamer that binds selectively to the anti-FLAG M2 antibody. The aptamer consisted of two motifs (CCTTA and TGTCTWCC) separated by 2-3 bases, and the elimination of one or the other motif abrogated binding. The DNA aptamer and FLAG peptide competed for binding to the antigen-binding pocket of the M2 antibody. In addition, the aptamer eluted FLAG-tagged proteins from the antibody, suggesting a commercial application in protein purification. These findings demonstrate the feasibility of

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