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Lee, Won Jun, and Tae Hee Han. "A Voltage Binning Technique Considering LVCC Margin Characteristics of Different Process Corners to Improve Power Consumption." Journal of the Institute of Electronics and Information Engineers 51, no. 7 (July 25, 2014): 122–29. http://dx.doi.org/10.5573/ieie.2014.51.7.122.
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Abdelsayed, Victor, M. Samy El-Shall, and Takafumi Seto. "Differential mobility analysis of nanoparticles generated by laser vaporization and controlled condensation (LVCC)." Journal of Nanoparticle Research 8, no. 3-4 (April 26, 2006): 361–69. http://dx.doi.org/10.1007/s11051-005-9015-z.
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Saoud, Khaled Mohammad, and Mohamed Samy El-Shall. "Physical and Chemical Synthesis of Au/CeO2 Nanoparticle Catalysts for Room Temperature CO Oxidation: A Comparative Study." Catalysts 10, no. 11 (November 20, 2020): 1351. http://dx.doi.org/10.3390/catal10111351.
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In many heterogeneous catalytic reactions, such as low-temperature CO oxidation, the preparation conditions, and the role of the CeO2 support (oxygen vacancies and redox properties) in the dispersion and the chemical state of Au, are considered critical factors for obtaining gold nanoparticle catalysts with high catalytic performance. In this work, the physical and chemical preparation methods were compared, aiming at understanding how the preparation method influences the catalytic activity. The Au/CeO2 nanoparticle catalysts with 5% Au loading were prepared via the Physical Laser Vaporization Controlled Condensation method (LVCC), and the chemical Deposition-Precipitation method (DP) was used to investigate the effect of synthesis methods on the structure and the catalytic activity toward the CO oxidation. In this manuscript, we compare the activity of nanostructured Au/CeO2 catalysts. The structure and the redox properties of the catalysts were investigated by the XRD, SEM, TEM, TPR, and XPS. The catalytic activity for low-temperature CO oxidation was studied using a custom-built quartz tube flow reactor coupled with an infrared detector system at atmospheric pressure. The study reveals that the prepared CeO2-supported Au nanoparticles’ catalytic activity was highly dependent on the preparation methods. It showed that the sample prepared by the DP method exhibits higher catalytic efficiency toward CO oxidation when compared with the sample prepared by the LVCC method. The high catalytic activity could be attributed to the small particle size and shape, slightly higher Au concentration at the surface, surface-active Au species such as Au1+, along with the large interface between Au and CeO2. This study suggests that the stability, dispersion of Au nanoparticles on CeO2, and strong interaction between Au and CeO2 lead to strong oxidation ability even below room temperature. Considering the universal character of different physical and chemical methods for Au/CeO2 preparation, this study may also provide a base for supported Au-based catalysts for many oxidation reactions in energy and environmental applications.
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BONIAL, CLAIRE, and KIMBERLY A. POLLARD. "Choosing an event description: What a PropBank study reveals about the contrast between light verb constructions and counterpart synthetic verbs." Journal of Linguistics 56, no. 3 (April 3, 2020): 577–600. http://dx.doi.org/10.1017/s0022226720000109.
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Light verb constructions (LVCs) in English and Romance languages are somewhat unique crosslinguistically because LVCs in these languages tend to have semantically similar synthetic verb counterparts (Zarco 1999): e.g. make an appearance and appear. This runs contrary to assumptions in linguistic theories that two competing forms are rarely maintained in a language unless they serve distinct purposes (e.g. Grice 1975). Why do English LVCs exist alongside counterpart synthetic verbs, especially given that synthetic verbs are arguably the more efficient form (Zipf 1949)? It has been proposed that LVCs serve an aspectual function (Prince 1972, Live 1973, Wierzbicka 1982, Tanabe 1999, Butt & Geuder 2001), as there are telic LVC counterparts (e.g. have a thought) of atelic verbs (e.g. think). This proposal has been difficult to evaluate without a large-scale resource providing a markup of both LVCs and counterpart verbs. Addressing this gap in resources, the present research describes the development of guidelines for LVC annotation in the English PropBank (Bonial & Palmer 2015). The focus of this article is the subsequent analysis of these annotations, aimed at uncovering corpus evidence of what contexts call for the use of an LVC over a synthetic verb. The corpus study shows that the general function of LVCs is not an aspectual one and provides distributional evidence that the ease and variety with which LVCs can be modified is the general motivating factor for the use of an LVC.
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Glaspell, Garry, Victor Abdelsayed, Khaled M. Saoud, and M. Samy El-Shall. "Vapor-phase synthesis of metallic and intermetallic nanoparticles and nanowires: Magnetic and catalytic properties." Pure and Applied Chemistry 78, no. 9 (January 1, 2006): 1667–89. http://dx.doi.org/10.1351/pac200678091667.
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In this paper, we present several examples of the vapor-phase synthesis of intermetallic and alloy nanoparticles and nanowires, and investigate their magnetic and catalytic properties. In the first example, we report the vapor-phase synthesis of intermetallic aluminide nanoparticles. Specifically, FeAl and NiAl nanoparticles were synthesized via laser vaporization controlled condensation (LVCC) from their bulk powders. The NiAl nanoparticles were found to be paramagnetic at room temperature, with a blocking temperature of approximately 15 K. The FeAl nanoparticles displayed room-temperature ferromagnetism. In the second example, we report the vapor-phase synthesis of cobalt oxide nanoparticle catalysts for low-temperature CO oxidation. The incorporation of Au and Pd nanoparticles into the cobalt oxide support leads to significantly improved catalytic activity and stability of the binary catalyst systems. Finally, we report the synthesis of nanowires of Ge, Mg, Pd, and Pt using the vapor-liquid-solid (VLS) method where the vapor-phase growth of the wire is catalyzed using a proper metal catalyst present in the liquid phase.
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Ong, Christina Sook Beng, and Hajar Abdul Rahim. "Nativised structural patterns of make light verb construction in Malaysian English." Concentric. Studies in Linguistics 47, no. 1 (April 19, 2021): 93–112. http://dx.doi.org/10.1075/consl.00024.rah.
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Abstract This study investigated nativised structural patterns of light verb constructions (LVCs) in Malaysian English using a corpus-based, descriptive approach to analyse grammatical innovations. To facilitate the analysis, a 100-million-word general corpus comprising threads from Lowyat.Net, a popular Internet forum in Malaysia, was created, and the British National Corpus (BNC) was used as the reference corpus. Using the Sketch Engine corpus tool, the three most frequently occurring make LVCs in the Malaysian English corpus were identified. The data was analysed to reveal the differences between the structures of make LVC in Malaysian English and its prototypical structure. The findings show that besides the non-isomorphic deverbal noun form, make LVCs in Malaysian English prefer taking the basic constituents of an LVC. Nativised LVCs are essentially those with zero articles and isomorphic deverbal nouns taking definite articles, determiners, and descriptive adjectives in their modifier slots. The zero article LVC is the most common nativised structure pattern due to the influence of substrate languages in Malaysian English.
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Azaioud, Hakim, Robbert Claeys, Jos Knockaert, Lieven Vandevelde, and Jan Desmet. "A Low-Voltage DC Backbone with Aggregated RES and BESS: Benefits Compared to a Traditional Low-Voltage AC System." Energies 14, no. 5 (March 4, 2021): 1420. http://dx.doi.org/10.3390/en14051420.
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The increasing penetration of PV into the distribution grid leads to congestion, causing detrimental power quality issues. Moreover, the multiple small photovoltaic (PV) systems and battery energy storage systems (BESSs) result in increasing conversion losses. A low-voltage DC (LVDC) backbone to interconnect these assets would decrease the conversion losses and is a promising solution for a more optimal integration of PV systems. The multiple small PV systems can be replaced by shared assets with large common PV installations and a large BESS. Sharing renewable energy and aggregation are activities that are stimulated by the European Commission and lead to a substantial benefit in terms of self-consumption index (SCI) and self-sufficiency index (SSI). In this study, the benefit of an LVDC backbone is investigated compared to using a low-voltage AC (LVAC) system. It is found that the cable losses increase by 0.9 percent points and the conversion losses decrease by 12 percent points compared to the traditional low-voltage AC (LVAC) system. The SCI increases by 2 percent points and the SSI increases by 6 percent points compared to using an LVAC system with shared meter. It is shown that an LVDC backbone is only beneficial with a PV penetration level of 65% and that the BESS can be reduced by 22% for the same SSI.
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Sharif, Babak, and Mohammad Amouzadeh. "A Cognitive Approach to Light Verb Constructions: Backstage Issues." International Journal of Linguistics 7, no. 3 (June 24, 2015): 15. http://dx.doi.org/10.5296/ijl.v7i3.7672.
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<p>Persian Light Verb Constructions (LVCs) have been studied by many scholars. Yet, little attention has been paid to the process of LVC formation. This paper aims to situate the components of Persian light verb constructions in contexts that can be justifiably invoked as a motivation for LVC formation. We will investigate the issue by arguing that Persian LVCs can be analyzed in terms of incorporation process. This process, explained from a cognitive viewpoint, involves LVCs originating from complete clauses, then passing through a <em>compositional path</em> (Langacker 1987, 2008) where a nonverbal and a verbal element are selected out of a kernel clause and end up in a complex predicate (CPr). The investigation will be primarily focused on the LVCs constructed with<em> </em>LV<em> kardan </em>‘do, make’, as the most frequently used light verb in Persian. The paper will also explore how different paths could be associated with certain particular ‘light’ meanings of<em> kardan. </em>The resulting LVCs may further yield <em>constructional schemas</em> upon which other LVCs formed with a given LV can be formed.</p><p><strong>Keywords: </strong>Light verb construction, Complex predicate, Incorporation, Persian</p>
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Parras-Alcántara, L., M. Martín-Carrillo, and B. Lozano-García. "Impacts of land use change in soil carbon and nitrogen in a Mediterranean agricultural area (Southern Spain)." Solid Earth 4, no. 1 (May 14, 2013): 167–77. http://dx.doi.org/10.5194/se-4-167-2013.
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Abstract. The agricultural Mediterranean areas are dedicated to arable crops (AC), but in the last decades, a significant number of AC has led to a land use change (LUC) to olive grove (OG) and vineyards (V). A field study was conducted to determine the long-term effects (46 years) of LUC (AC by OG and V) and to determine soil organic carbon (SOC), total nitrogen (TN), C : N ratio and their stratification across the soil entire profile, in Montilla-Moriles denomination of origin (D.O.), in Calcic-Chromic Luvisols (LVcc/cr), an area under semiarid Mediterranean conditions. The experimental design consisted of studying the LUC on one farm between 1965 and 2011. Originally, only AC was farmed in 1965, but OG and V were farmed up to now (2011). This LUC principally affected the horizon thickness, texture, bulk density, pH, organic matter, organic carbon, total nitrogen and C : N ratio. The LUC had a negative impact in the soil, affecting the SOC and TN stocks. The conversion from AC to V and OG involved the loss of the SOC stock (52.7% and 64.9% to V and OG respectively) and the loss of the TN stock (42.6% and 38.1% to V and OG respectively). With respect to the stratification ratios (SRs), the effects were opposite; 46 years after LUC increased the SRs (in V and OG) of SOC, TN and C : N ratio.
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Martín-Carrillo, M., L. Parras-Alcántara, and B. Lozano-García. "Land-use change effects on soil quality in Montilla-Moriles DO, Southern Spain." Solid Earth Discussions 5, no. 1 (February 22, 2013): 163–87. http://dx.doi.org/10.5194/sed-5-163-2013.
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Abstract. The agricultural Mediterranean areas are dedicated to arable crops (AC), but in the last few decades, a significant number of AC has a land use change (LUC) to olive grove cultivations (OG) and vineyards (V). A field study was conducted to determine the long-term effects (46 yr) of LUC (AC by OG and V) and to determine soil organic carbon (SOC), total nitrogen (TN), C:N ratio and their stratification across the soil entire profile, in Montilla-Moriles denomination of origin (DO), in Calcic-Chromic Luvisols (LVcc/cr), an area under semiarid Mediterranean conditions. The experimental design consisted of studying the LUC on one farm between 1965 and 2011. Originally, only AC was farmed in 1965, but OG and V were farmed up to now (2011). This LUC principally affected the thickness horizon, texture, bulk density, pH, organic matter, organic carbon, total nitrogen and C:N ratio. The LUC had a negative impact in the soil, affecting the SOC and TN stocks. The conversion from AC to V and OG involved the loss of the SOC stock (52.7% and 64.9% to V and OG, respectively) and the loss of the TN stock (42.6% and 38.1% to V and OG, respectively). With respect to the soil quality, the effect was opposite; 46\\,yr after LUC improved the soil quality, increasing the stratification ratio (in V and OG) of SOC, TN and C:N ratio.
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Lee, Kyung-Min, and Chul-Won Park. "Ground Fault Detection Using Hybrid Method in IT System LVDC Microgrid." Energies 13, no. 10 (May 20, 2020): 2606. http://dx.doi.org/10.3390/en13102606.
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Low voltage direct current (LVDC) microgrid systems have many advantages over low voltage alternating current (LVAC) systems. Furthermore, LVDC microgrids are growing in use because they are easy to link to distributed energy resources (DER) and energy storage systems (ESS), etc. Currently, IT system LVDC microgrids are widely used in direct current (DC) railways, hospitals, photovoltaic (PV) systems, and so on. When a ground fault occurs in an IT system LVDC microgrid, the ground fault may not be detected because the fault current is very small and there is no current path. In this paper, ground fault detection is proposed using a hybrid method that comprises pulsation signal generator injection and detailed coefficients of discrete wavelet transform (DWT). The LVDC microgrid was modeled and simulated using power systems computer-aided design (PSCAD). In addition, the proposed hybrid method was implemented using MATLAB’s wave menu, a script m-file, and the PSCAD library. The proper threshold was selected and tested by fault resistance change and load variation. In order to verify the superiority of the proposed hybrid method, a comparative study with the conventional method was performed. The results of various simulations show that the proposed hybrid detection method has normal operation and accurately and rapidly detects ground faults.
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Buckingham, Louisa. "Light verb constructions in Latin American newspapers." Spanish in Context 10, no. 1 (April 5, 2013): 114–35. http://dx.doi.org/10.1075/sic.10.1.05buc.
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This article examines the occurrence of variant forms of Spanish light verb constructions (LVCs) in a seven-million-word corpus of contemporary newspaper texts from seven Latin American countries. The findings from this corpus are compared with results from a previous study using a corpus of scholarly writing; additional information from a diachronic perspective is provided by data from the Corpus del Español. The structures selected for discussion are complex LVCs (e.g., tener un vínculo o relación), and tokens containing calques (e.g., dar un clic), loan words (e.g., tener un look) and affixes (e.g., dar goplecitos). This study provides evidence of the creative and expressive potential of less frequent types of these formulaic structures. While tokens containing calques and loan words appear almost exclusively in the newspaper corpus, complex LVCs appear with comparable frequency in both corpora. The discussion of the morphosyntactic features of these variant LVC types is accompanied by examples extracted from the corpus.
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Nagy T., István, Anita Rácz, and Veronika Vincze. "Detecting light verb constructions across languages." Natural Language Engineering 26, no. 3 (July 15, 2019): 319–48. http://dx.doi.org/10.1017/s1351324919000330.
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AbstractLight verb constructions (LVCs) are verb and noun combinations in which the verb has lost its meaning to some degree and the noun is used in one of its original senses, typically denoting an event or an action. They exhibit special linguistic features, especially when regarded in a multilingual context. In this paper, we focus on the automatic detection of LVCs in raw text in four different languages, namely, English, German, Spanish, and Hungarian. First, we analyze the characteristics of LVCs from a linguistic point of view based on parallel corpus data. Then, we provide a standardized (i.e., language-independent) representation of LVCs that can be used in machine learning experiments. After, we experiment on identifying LVCs in different languages: we exploit language adaptation techniques which demonstrate that data from an additional language can be successfully employed in improving the performance of supervised LVC detection for a given language. As there are several annotated corpora from several domains in the case of English and Hungarian, we also investigate the effect of simple domain adaptation techniques to reduce the gap between domains. Furthermore, we combine domain adaptation techniques with language adaptation techniques for these two languages. Our results show that both out-domain and additional language data can improve performance. We believe that our language adaptation method may have practical implications in several fields of natural language processing, especially in machine translation.
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Lehmann, A., and P. Post. "Variability of atmospheric circulation patterns associated with large volume changes of the Baltic Sea." Advances in Science and Research 12, no. 1 (October 29, 2015): 219–25. http://dx.doi.org/10.5194/asr-12-219-2015.
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Abstract. Salinity and stratification in the deep basins of the Baltic Sea are linked to the occurrence of Major Baltic Inflows (MBIs) of higher saline water of North Sea origin, which occur sporadically and transport higher saline and oxygenated water to deeper layers. Since the mid-1970s, the frequency and intensity of MBIs have decreased. They were completely absent between February 1983 and January 1993. However, in spite of the decreasing frequency of MBIs, there was no obvious decrease of larger Baltic Sea volume changes (LVCs). A LVC is defined by a total volume change of at least 100 km3. LVCs can be identified from the sea level changes at Landsort which is known to represent the mean sea level of the Baltic Sea very well. Strong inflows leading to LVCs are associated to a special sequence of atmospheric circulation patterns. Our analysis based on Jenkinson-Collison circulation (JCC) types confirms that most effective inflows occur if about a month before the main inflow period, eastern air flow with anticyclonic vorticity over the western Baltic prevails. These conditions reduce the mean sea level of the Baltic Sea and lead to an increased saline stratification in the Belt Sea area. An immediate period of strong to very strong westerly winds trigger the inflow and force LVCs/MBIs. The lack of MBIs coincide with a negative trend of eastern types and a parallel increase of western type JCCs.
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FLEISCHHAUER, JENS, and MOZHGAN NEISANI. "Adverbial and attributive modification of Persian separable light verb constructions." Journal of Linguistics 56, no. 1 (January 14, 2019): 45–85. http://dx.doi.org/10.1017/s0022226718000646.
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Persian makes extensive use of light verb constructions (LVCs) consisting of a non-verbal preverb and a semantically light verbal element. The current paper concentrates on LVCs with nominal preverbs (e.g. sedâ dâdan ‘produce a sound’, lit. ‘sound give’) which license an attributively used adjective intervening between the two components of the construction. Such LVCs are idiomatically combining expressions, in the sense of Nunberg, Sag & Wasow (1994: 496). The individual components of idiomatically combining expressions have an identifiable meaning and combine in a non-arbitrary way. Thus, they are conceived as being formed compositionally. Evidence for this view can be taken from the fact that the attributively used adjectives function as internal modifiers, targeting only the nominal component of the LVC.As adjectives can also be used adverbially, two modification patterns emerge: The nominal preverb is modified by an attributive modifier, or the same adjective can be used as an adverbial modifier of the whole LVC. Two corresponding interpretation patterns arise: Attributive and adverbial modification either both result in the same, or in different interpretations.The paper makes the following claims: First, only compositionally derived LVCs license attributive modification of their nominal preverb; and second, different interpretations of the two modification patterns only result if the light verb and the preverb each license a suitable property as a target for the modifier. If, on the other hand, such a property is only licensed by the preverb, adverbial and attributive modification result in the same interpretation.
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Hainzer, Kirt, Talitha Best, and Philip Hugh Brown. "Local value chain interventions: a systematic review." Journal of Agribusiness in Developing and Emerging Economies 9, no. 4 (September 26, 2019): 369–90. http://dx.doi.org/10.1108/jadee-11-2018-0153.
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Purpose The purpose of this paper twofold: first, to review the current state of knowledge regarding local value chain (LVC) interventions in the context of international agricultural research and development; and, secondly, by synthesising the empirical findings from LVC projects, to provide guidance for future research and intervention design. Design/methodology/approach This paper utilises systematic review and qualitative meta-synthesis guidelines to review and synthesise recent research papers and case studies dealing specifically with the development of LVCs, authored by professionals affiliated with development agencies and international research consortiums. Findings The paper identifies a novel two-phase characterisation of LVC interventions. Phase 1 identifies opportunities for interventions, which are characterised as typologies and presented upon a spectrum of value chain functionality from underdeveloped to mature. Phase 2 is the selection and implementation of strategies to achieve the identified opportunities from Phase 1, and the paper characterises these strategies per the domain of value chain functionality which they target. Research limitations/implications The interaction between context, socio-economic constraints and intervention strategies is still a poorly understood feature of value chain interventions, and the paper posits that a greater understanding of these interactions is crucial to the success of value chain interventions. Originality/value The paper provides the first synthesis of LVC interventions, while outlining research priorities and knowledge gaps required to design interventions which are consummate to the context and functionality of a prioritised chain.
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Nuutinen, Pasi, Tero Kaipia, Janne Karppanen, Aleksi Mattsson, Andrey Lana, Antti Pinomaa, Pasi Peltoniemi, Jarmo Partanen, Mika Luukkanen, and Tomi Hakala. "LVDC rules – technical specifications for public LVDC distribution network." CIRED - Open Access Proceedings Journal 2017, no. 1 (October 1, 2017): 293–96. http://dx.doi.org/10.1049/oap-cired.2017.0519.
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Lee, Heenam. "Trends of developing training in advanced countries and direction of the Army." Journal of Advances in Military Studies 3, no. 2 (August 31, 2020): 1–15. http://dx.doi.org/10.37944/jams.v3i2.73.
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This study examines the history of LVCG training, which is attracting attention as the army’s education and training method in the era of the 4th industrial revolution, and the recent trends in advanced countries, and the direction of the army’s LVCG training development. LVCG training is an effective means for soldiers to improve their survival rate and combat skills by experiencing realistic virtual battles iteratively prior to actual deployment, thereby ultimately improving their readiness. The LVCG training system is classified into four categories: live, virtual training, war game training, and game, collectively referred to as LVCG. In the 1980s, advanced countries began to use the LVCG training system in various areas of education and training, and after the 1990s, they promoted a synthetic environment incorporating the LVCG training system. Recently, the synthetic training environment (STE) that integrates LVCG into a three-dimensional virtual environment. This is attracting attention and developed countries are rapidly transitioning to STE. The Army is also promoting education and training innovation based on big data and artificial intelligence by establishing a low-cost, highly efficient LVCG training environment with LVCG integrated around the synthetic training environment platform and securing education and training data using STE.
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Poedjiastoeti, Hermin, Sudarmadji Sudarmadji, Sunarto Sunarto, and Slamet Suprayogi. "Penilaian Kerentanan Air Permukaan terhadap Pencemaran di Sub DAS Garang Hilir Berbasis Multi-Indeks." Jurnal Wilayah dan Lingkungan 5, no. 3 (December 29, 2017): 167. http://dx.doi.org/10.14710/jwl.5.3.167-180.
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Assessing the surface water vulnerability to pollution in the Garang Downstream Watershed Semarang requires a study concerned with some environmental components/indicators. Vulnerability measurement through surface water susceptibility index formulation on pollution is important considering the absence of surface water pollution effect indicators in an efficient assessment system. Therefore, a multi-indicator vulnerability assessment on surface water pollution is necessary. The Surface Water Vulnerability Index to Pollution (SWVIP) is composed of five components, namely water quality (WQ), rainfall (R), land use and vegetation cover (LVC), river hydrogeometric (RH) and population (P). Regarding index development, the subindex graphs and the weighting of each component are created. The application of composite index measurement yields an equation of SWVIP = 0.29.WQI + 0.23PI + 0.14RI + 0.20.LVCI + 0.14.RHI and an index value of 73.87 including the "rather high" category that represents the "vulnerable"condition in the Garang Downstream Watershed Semarang. This suggests that the five selected components used in the index creation can provide useful information to decision making in the surface water pollution control.
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Poedjiastoeti, Hermin, Sudarmadji Sudarmadji, Sunarto Sunarto, and Slamet Suprayogi. "Penilaian Kerentanan Air Permukaan terhadap Pencemaran di Sub DAS Garang Hilir Berbasis Multi-Indeks." Jurnal Wilayah dan Lingkungan 5, no. 3 (December 29, 2017): 168. http://dx.doi.org/10.14710/jwl.5.3.168-180.
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Assessing the surface water vulnerability to pollution in the Garang Downstream Watershed Semarang requires a study concerned with some environmental components/indicators. Vulnerability measurement through surface water susceptibility index formulation on pollution is important considering the absence of surface water pollution effect indicators in an efficient assessment system. Therefore, a multi-indicator vulnerability assessment on surface water pollution is necessary. The Surface Water Vulnerability Index to Pollution (SWVIP) is composed of five components, namely water quality (WQ), rainfall (R), land use and vegetation cover (LVC), river hydrogeometric (RH) and population (P). Regarding index development, the subindex graphs and the weighting of each component are created. The application of composite index measurement yields an equation of SWVIP = 0.29.WQI + 0.23PI + 0.14RI + 0.20.LVCI + 0.14.RHI and an index value of 73.87 including the "rather high" category that represents the "vulnerable"condition in the Garang Downstream Watershed Semarang. This suggests that the five selected components used in the index creation can provide useful information to decision making in the surface water pollution control.
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Mazzarotto, Francesco, Megan H. Hawley, Matteo Beltrami, Leander Beekman, Antonio de Marvao, Kathryn A. McGurk, Ben Statton, et al. "Systematic large-scale assessment of the genetic architecture of left ventricular noncompaction reveals diverse etiologies." Genetics in Medicine 23, no. 5 (January 26, 2021): 856–64. http://dx.doi.org/10.1038/s41436-020-01049-x.
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Abstract Purpose To characterize the genetic architecture of left ventricular noncompaction (LVNC) and investigate the extent to which it may represent a distinct pathology or a secondary phenotype associated with other cardiac diseases. Methods We performed rare variant association analysis with 840 LVNC cases and 125,748 gnomAD population controls, and compared results to similar analyses on dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM). Results We observed substantial genetic overlap indicating that LVNC often represents a phenotypic variation of DCM or HCM. In contrast, truncating variants in MYH7, ACTN2, and PRDM16 were uniquely associated with LVNC and may reflect a distinct LVNC etiology. In particular, MYH7 truncating variants (MYH7tv), generally considered nonpathogenic for cardiomyopathies, were 20-fold enriched in LVNC cases over controls. MYH7tv heterozygotes identified in the UK Biobank and healthy volunteer cohorts also displayed significantly greater noncompaction compared with matched controls. RYR2 exon deletions and HCN4 transmembrane variants were also enriched in LVNC, supporting prior reports of association with arrhythmogenic LVNC phenotypes. Conclusion LVNC is characterized by substantial genetic overlap with DCM/HCM but is also associated with distinct noncompaction and arrhythmia etiologies. These results will enable enhanced application of LVNC genetic testing and help to distinguish pathological from physiological noncompaction.
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Vaikhanskaya, T. G., L. N. Sivitskaya, T. V. Kurushko, O. G. Nizhnikava, O. D. Levdanskiy, and N. G. Danilenko. "Left ventricular noncompaction: a distinct cardiomyopathy or a composite anatomical syndrome?" Kardiologiia 58, no. 11S (December 14, 2018): 33–45. http://dx.doi.org/10.18087/cardio.2558.
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Left ventricular non-compaction (LVNC) is characterized by hypertrabecularity (thickened non-compact layer) with deep intertrabecular recesses that are continuous with the ventricle cavity, and a thin compact layer. The phenotypes of LVNС are extremely variable: the left or right ventricular variant, biventricular form, LVNC with symptoms of heart failure or arrhythmia, asymptomatic forms or variants with thromboembolic events. In 30–50 % of patients with LVNC genetic mutations of genes encoding sarcomeric or cytoskeletal proteins are revealed by a genetic study. The article presents a literature review on the problems of diagnosis, visualization, pathogenesis, variability of clinical manifestations of LVNC and its genetic heterogeneity. Clinical cases demonstrating LVNC as a concomitant anatomical syndrome due to monogenic Danone disease, as well as the family cardiomyopathy with the digenic inheritance of two phenotypes (LVNC with DCM) and the unique case of peripartum evolution of the acquired LVNC syndrome, all these cases are reflect the current uncertainty regarding to the pathogenesis and significance of LVNC. The main question is whether LVNC is a distinct cardiomyopathy or a morphologic trait and a composite anatomical syndrome of congenital heart disease or other cardiomyopathies (DCM, HCM, ARVC) remains controversial. Achievement of professional consensus guidelines about unification of diagnostic criteria and risk-stratification of LVNC, improvement of visualization tools and expansion of genetic testing will help to significantly expand our knowledge and understanding of the pathogenesis, clinical significance and prognosis of LVNC for optimization of the treatment strategy
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van Keulen, Pieter. "Dertig jaar lvsc." Supervisie en coaching 28, no. 1 (March 2011): 35–36. http://dx.doi.org/10.1007/s12492-011-0004-9.
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Kovalevskaitė, Jolanta, Erika Rimkutė, and Laura Vilkaitė-Lozdienė. "Light Verb Constructions in Lithuanian: Identification and Classification." Studies About Languages, no. 36 (July 1, 2020): 5–16. http://dx.doi.org/10.5755/j01.sal.0.36.22846.
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Light verb constructions (LVCs) are verb-noun constructions in which the noun carries the semantic meaning and the verb is semantically reduced, when compared with its main meaning, for example, atlikti analizę (‘to perform an analysis’). LVCs in Lithuanian have not been addressed much so far. The analysis of Lithuanian LVCs was carried out as a part of the PARSEME project on verbal identification of multiword expressions (MWE). This paper aims at presenting some initial findings on the identification of LVCs in Lithuanian, based on the 1st edition of the PARSEME shared-task results (2017). We describe the identification process according to the semantic and syntactic features of LVCs (PARSEME guidelines 1.0 2017) and discuss the grammatical features of the identified Lithuanian LVCs.
LVCs seem to be less frequent in Lithuanian than in other languages: they make up about 0.2% (215 instances) of the analysed 200,000 token corpus. Based on the number of different LVCs, there seem to be two groups of verbs functioning as light verbs: a relatively small group of common light verbs used in the most prototypical examples of Lithuanian LVCs (e.g., vykdyti ‘to perform’, atlikti ‘to perform’, daryti ‘to do’, and turėti ‘to have’) and a larger group of less common light verbs. Most of the nouns in analysed LVCs have suffixes -imas and -ymas, which are the most typical Lithuanian suffixes for deriving a noun from a verb. Almost 40% of all LVCs are used with 1–3 words intervening between a verb and a noun.
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Kulikova, Olga V., Roman P. Myasnikov, Elena A. Mershina, Polina S. Pilus, Sergei N. Koretskiy, Aleksei N. Meshkov, Anna V. Kiseleva, et al. "Familial left ventricular noncompaction: phenotypes and clinical course. Results of the multicenter registry." Terapevticheskii arkhiv 93, no. 4 (April 15, 2021): 381–88. http://dx.doi.org/10.26442/00403660.2021.04.200677.
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Aim. To analyze and demonstrate various phenotypes in patients with familial left ventricular noncompaction (LVNC).
Materials and methods. In 2013 was created a multicenter registry of LVNC patients. On its basis 30 families with a familial LVNC were selected.
Results. 30 LVNC families were selected from the register. From a total of 115 people (probands and relatives) in 71 (61.7%) LVNC was diagnosed (30 probands and 41 relatives with non-compact myocardial criteria). The most common type of remodeling in patients was the dilated type (DT) (n=30), the isolated LVNC with preserved ejection fraction (EF) was slightly less common (n=23), and the hypertrophic type (GT) was detected in 8 patients. 4 patients were diagnosed with the isolated LVNC with a reduced EF. 3 patients were with a combination of non-compact myocardium with congenital heart disease and with a combination of DT and GT (DT+GT). During the analysis of cases a combination of different phenotypes in the same family was observed. The largest number of families was diagnosed with a combination of DT and the isolated LVNC with preserved EF. The development of cardiovascular complications was associated with DT.
Conclusion. Family cases of LVNC had different types of myocardial remodeling and variants of clinical course. In one family a combination of different types of left ventricular remodeling is possible. DT is associated with the most severe clinical manifestations. The clinical picture of the isolated LVNC with preserved EF, is the most favorable, but in rare cases, serious clinical manifestations were observed.
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Lutokhina, Yu A., O. V. Blagova, A. G. Shestak, M. Е. Polyak, A. A. Bukaeva, E. V. Zaklyazminskaya, N. V. Varionchik, et al. "Combination of Arrhythmogenic Right Ventricular Dysplasia with Left Ventricular Non-Compaction as a Special Form of Cardiomyopathy: Clinic, Diagnostics, Genetic, Natural Course." Annals of the Russian academy of medical sciences 75, no. 6 (November 15, 2020): 594–604. http://dx.doi.org/10.15690/vramn1245.
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Background. A few cases of combination of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) with left ventricular noncompaction (LVNC) have been described. Aims to study the genetics, diagnostical features and clinical course of the combination of ARVC with LVNC. Methods. 58 patients with ARVC diagnosis (26 men; mean age 39.1 14.2 years; mean follow-up period 21.5 [6; 60] months) and 125 patients with LVNC (74 men; mean age 46.4 15.1 years; mean follow-up period 14 [3; 40] months). All patients underwent electrocardiogram (ECG), echocardiography, 24-h ECG monitoring. Heart MRI was performed in 53 (91.4%) patients with ARVC and 60 (48%) with LVNC, heart CT in 18 (31%) patients with ARVC and 89 (71.2%) with LVNC. For all patients with combination of ARVC and LVNC DNA-diagnostic was performed using both ARVC (PKP2, DSG2, DSP, DSC2, JUP, TMEM43, TGFB3, PLN, LMNA, DES, CTTNA3, EMD, SCN5A, LDB3, CRYAB, FLNC) and LVNC (MYH7, MYBPC3, TAZ, TPM1, LDB3, MYL2, MYL3, ACTC1, TNNT2, TNI3) gene panels. Results. Combination of ARVC and LVNC was found in 9 patients (15.5% of patients form ARVC cohort and 7.2% from LVNC cohort). These patients were distinguished from patients with isolated ARVC or LVNC by aggressive ventricular arrhythmias (frequent premature ventricular beats, sustained ventricular tachycardia, significantly worse antiarrhythmic therapy effect, appropriate shocks of implanted cardioverter-defibrillators (ICD) in all patients with ICD). Patients with combination of ARVC + LVNC were also distinguished from patients with isolated LVNC by the dilatation of RV, low QRS voltage on ECG, presence of AV block, absence of signs of LV hypertrophy on ECG. LV dilatation with reduction of its ejection fraction distinguished patients with mixed cardiomyopathy from patients with isolated ARVC. Potentially pathogenic variants (IVV classes of pathogenicity) and variants of unclear clinical significance (III class of pathogenicity) were found in both desmosomal and non-desmosomal genes in 78% of patients, including 3 (33%) in DSP gene. Conclusions. The combination of ARVC and LVNC can be caused by mutations in both desmosomal and non-desmosomal genes and has typical features: aggressive, resistant ventricular rhythm abnormalities leading to appropriate ICD shocks and a high risk of sudden cardiac death.
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Umarova, Malika K., E. N. Basargina, and I. E. Smirnov. "Left ventricular noncompaction in children: clinical manifestations and prognosis." Russian Pediatric Journal 19, no. 3 (April 30, 2019): 174–82. http://dx.doi.org/10.18821/1560-9561-2016-19-3-174-182.
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Left ventricular noncompaction (LVNC) is a disease of myocardium presumably caused by developmental arrest during embryogenesis. LVNC is characterized by the presence of pathological trabeculae in left ventricle. LVNC can be associated with different congenital heart diseases. Different types of myocardium remodeling are follows: dilated, hypertrophic, restrictive and mixed phenotypes. It is unclear whether LVNC is a distinct disease or a morphological feature of different cardiomyopathies. Distinction between pathological trabeculae constituting LVNC and normal phenotype is often difficult. For the time present the considerable attention is paid to the study of disease. Despite the progress in the study of the disease significant controversy remains around understanding of etiology, pathogenesis, clinical characteristics and prognosis of LVNC. Current literature review is aimed to discuss mentioned aspects with a focus on pediatric population.
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McGee, Michael, Luke Warner, and Nicholas Collins. "Ebstein’s Anomaly, Left Ventricular Noncompaction, and Sudden Cardiac Death." Case Reports in Cardiology 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/854236.
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Ebstein’s anomaly is a congenital disorder characterized by apical displacement of the septal leaflet of the tricuspid valve. Ebstein’s anomaly may be seen in association with other cardiac conditions, including patent foramen ovale, atrial septal defect, and left ventricular noncompaction (LVNC). LVNC is characterized by increased trabeculation within the left ventricular apex. Echocardiography is often used to diagnose LVNC; however, magnetic resonance (MR) imaging offers superior characterization of the myocardium. We report a case of sudden cardiac death in a patient with Ebstein’s anomaly with unrecognized LVNC noted on post mortem examination with screening documenting the presence of LVNC in one of the patient’s twin sons.
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Ren, Chongyu, Jin Zhang, Kenneth D. Philipson, Michael I. Kotlikoff, Mordecai P. Blaustein, and Donald R. Matteson. "Activation of L-type Ca2+ channels by protein kinase C is reduced in smooth muscle-specific Na+/Ca2+ exchanger knockout mice." American Journal of Physiology-Heart and Circulatory Physiology 298, no. 5 (May 2010): H1484—H1491. http://dx.doi.org/10.1152/ajpheart.00965.2009.
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L-type voltage-gated Ca2+ channels (LVGCs) are functionally downregulated in arterial smooth muscle (SM) cells (ASMCs) of mice with SM-specific knockout of Na+/Ca2+ exchanger type-1 (NCX1SM−/−) ( 32 ). Here, using activators and inhibitors of protein kinase C (PKC), we explore the regulation of these channels by a PKC-dependent mechanism. In both wild-type (WT) and NCX1SM−/− myocytes, the PKC activator phorbol 12,13-dibutyrate (PDBu) increases LVGC conductance, decreases channel closing rate, and shifts the voltage dependence of channel opening to more negative potentials. Three different PKC inhibitors, bisindolylmaleimide, Ro-31-8220, and PKC 19-31, all decrease LVGC currents in WT myocytes and prevent the PDBu-induced increase in LVGC current. Dialysis of WT ASMCs with activated PKC increases LVGC current and decreases channel closing rate. These results demonstrate that PKC activates LVGCs in ASMCs. The phosphatase inhibitor calyculin A increases LVGC conductance by over 50%, indicating that the level of LVGC activation is a balance between phosphatase and PKC activities. PDBu causes a larger increase in LVGC conductance and a larger shift in voltage dependence in NCX1SM−/− myocytes than in WT myocytes. The inhibition of PKC with PKC 19-31 decreased LVGC conductance by 65% in WT myocytes but by only 37% in NCX1SM−/− myocytes. These results suggest that LVGCs are in a state of low PKC-induced phosphorylation in NCX1SM−/− myocytes. We conclude that in NCX1SM−/− myocytes, reduced Ca2+ entry via NCX1 lowers cytosolic [Ca2+], thereby reducing PKC activation that lowers LVGC activation.
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Di Toro, Alessandro, Lorenzo Giuliani, Alexandra Smirnova, Valentina Favalli, Alessandra Serio, Mario Urtis, Maurizia Grasso, and Eloisa Arbustini. "Myths to debunk: the non-compacted myocardium." European Heart Journal Supplements 22, Supplement_L (November 1, 2020): L6—L10. http://dx.doi.org/10.1093/eurheartj/suaa124.
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Abstract Left ventricular non-compaction (LVNC) is defined by the triad: prominent trabecular anatomy, thin compacted layer, and deep inter-trabecular recesses. No person, sick or healthy, demonstrates identical anatomy of the trabeculae; their configuration represents a sort of individual dynamic ‘cardiac fingerprinting’. LVNC can be observed in healthy subjects with normal left ventricular (LV) size and function, in athletes, in pregnant women, as well as in patients with haematological disorders, neuromuscular diseases, and chronic renal failure; it can be acquired and potentially reversible. When LVNC is observed in patients with dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy, restrictive cardiomyopathy, or arrhythmogenic cardiomyopathy, the risk exists of misnaming the cardiomyopathy as ‘LVNC cardiomyopathy’ rather than properly describe, i.e. a ‘DCM associated with LVNC’. In rare infantile CMPs (the paradigm is tafazzinopathy or Barth syndrome), the non-compaction (NC) is intrinsically part of the cardiac phenotype. The LVNC is also common in congenital heart disease (CHD) as well as in chromosomal disorders with systemic manifestations. The high prevalence of LVNC in healthy athletes, its possible reversibility or regression, and the increasing detection in healthy subjects suggest a cautious use of the term ‘LVNC cardiomyopathy’, which describes the morphology, but not the functional profile of the cardiac disease. Genetic testing, when positive, usually reflects the genetic causes of an underlying cardiomyopathy rather than that of the NC, which often does not segregate with CMP phenotype in families. Therefore, when associated with LV dilation and dysfunction, hypertrophy, or CHD, the leading diagnosis is cardiomyopathy or CHD followed by the descriptor LVNC.
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Bojic, Danijela, Milos Kostic, Miljana Radovic-Vucic, Nena Velinov, Slobodan Najdanovic, Milica Petrovic, and Aleksandar Bojic. "Removal of the herbicide 2,4-dichlorophenoxyacetic acid from water by using an ultrahighly efficient thermochemically activated carbon." Chemical Industry 73, no. 4 (2019): 223–37. http://dx.doi.org/10.2298/hemind190411019b.
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Lagenaria vulgaris activated carbon (LVAC) was synthesized from Lagenaria vulgaris biomass by treatment with diluted H2SO4 followed by thermo-chemical carbonization and overheated steam activation process and used for removal of the herbicide 2,4-dichlo-rophenoxyacetic acid (2,4-D). Fourier transform infrared spectroscopy (FTIR) indicated that 2,4-D is adsorbed in micropores of the very porous LVAC (665 m2 g-1). LVAC showed high sorption capacity as compared to many previously used sorbents at optimal conditions: the stirring rate of 300 rpm, the sorbent dose of 1.0 g dm-3 and pH from 2 to 7. The experimental maximum sorption capacity of LVAC was 333.3 mg g-1. The pseudo-second-order model and Chrastil model described the 2,4-D sorption kinetics by LVAC. Thermodynamic studies have indicated that the sorption process was endothermic, spontaneous and physical in nature. LVAC was shown to be an ultrahighly efficient sorbent for removal of 2,4-D from groundwater, which could be also recycled and reused.
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Komissarova, S. M., N. M. Rineiska, N. N. Chakova, and S. S. Niyazova. "Overlapping Phenotype: Left Ventricular non-Compaction and Hypertrophic Cardiomyopathy." Kardiologiia 60, no. 4 (May 4, 2020): 137–45. http://dx.doi.org/10.18087/cardio.2020.4.n728.
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Aim To study the clinical course of the mixed phenotype (hypertrophic cardiomyopathy, HCMP, and left ventricular noncompaction, LVNC); to determine its genetic causes; and to evaluate incidence of cardiovascular complications (CVC) during the follow-up period.Material and methods In screening of 286 patients with HCMP, 8 of them (2.8 %; median age, 41.5 years; 4 men and 4 women) from unrelated families were found to have the mixed phenotype (combination of HCMP and LVNC). For their 10 first-degree relatives, the most frequent phenotype was HCMP without LVNC; however, both isolated LVNC and the mixed phenotype were also observed. Criteria for HCMP and LVNC were confirmed by echocardiography and cardiac magnetic resonance imaging Genotyping was performed by high-throughput sequencing NGT using the TruSight Cardio Sequencing Panel kit.Results Probands with the HCMP+LVNC combination compared to first-degree relatives with isolated HCMP and LVNC were characterized by more pronounced left ventricular dysfunction (ejection fraction, 43.57±7.6 and 53.64±6.51 %, respectively; p<0.001), a higher risk of CVC, and a higher incidence of ventricular tachyarrhythmias (7.9 and 2.2 %, respectively; p<0.01). 11 mutations in 5 genes were found in 8 patients with the mixed phenotype. 72.7 % of mutations were in the MYH7 and MYBPC3 genes that encode the heavy chain of β-myosin and myosin-binding protein C, respectively; however, in some cases, replacements in other genes (DTNA, TGFB2) were also found.Conclusion The mixed phenotype (HCMP and LVNC) is associated with more severe clinical course of the disease and unfavorable CVC.
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Ammous, Anis, Ammar Assaidi, Abdulrahman Al Ahdal, and Kaiçar Ammous. "Energy Efficiency Performances of LVDC Nanogrids Powered Buildings." Journal of Engineering 2021 (April 14, 2021): 1–11. http://dx.doi.org/10.1155/2021/6625380.
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The Low Voltage Direct Current (LVDC) system concept has been growing in the recent times due to its characteristics and advantages like renewable energy source compatibility, more straightforward integration with storage utilities through power electronic converters, and distributed loads. This paper presents the energy efficiency performances of a proposed LVDC supply concept and other classical PV chains architectures. A PV source was considered in the studied nanogrids. The notion of relative saved energy (RSE) was introduced to compare the studied PV systems energy performances. The obtained results revealed that the use of the proposed LVDC chain supply concept increases the nanogrid efficiency. The installed PV power source in the building should be well sized regarding the consumed power in order to register a high system RSE. The efficiency of the new LVDC architecture is 10% higher than the conventional LVDC one.
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Marques, Laís Costa, Gabriel Romero Liguori, Ana Carolina Amarante Amarante Souza, and Vera Demarchi Aiello. "Left Ventricular Noncompaction Is More Prevalent in Ventricular Septal Defect Than Other Congenital Heart Defects: A Morphological Study." Journal of Cardiovascular Development and Disease 7, no. 4 (September 25, 2020): 39. http://dx.doi.org/10.3390/jcdd7040039.
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Left ventricular noncompaction (LVNC) is a condition characterized by prominent ventricular trabeculae and deep intertrabecular recesses and has been described as a possible substrate for arrhythmias, thromboembolism, and heart failure. Herein, we explored the prevalence of LVNC morphology among hearts with congenital heart defects (CHD). We examined 259 postnatal hearts with one of the following CHD: isolated ventricular septal defect (VSD); isolated atrial septal defect (ASD); atrioventricular septal defect (AVSD); transposition of the great arteries (TGA); isomerism of the atrial appendages (ISOM); Ebstein’s malformation (EB); Tetralogy of Fallot (TF). Eleven hearts from children who died of non-cardiovascular causes were used as controls. The thickness of the compacted and non-compacted left ventricular myocardial wall was determined and the specimens classified as presenting or not LVNC morphology according to three criteria, as proposed by Chin, Jenni, and Petersen. Normal hearts did not present LVNC, but the CHD group presented different percentages of LVNC in at least one diagnostic criterium. The prevalence of LVNC was respectively, according to Chin’s, Jenni´s and Petersen´s methods: for VSD—54.2%, 35.4%, and 12.5%; ASD—8.3%, 8.3%, and 8.3%; AVSD—2.9%, 2.9%, and 0.0%; TGA—22.6%, 17%, and 5.7%; ISOM—7.1%, 7.1%, and 7.1%; EB—28.6%, 9.5%, and 0.0%; TF—5.9%. 2.9%, and 2.9%. VSD hearts showed a significantly greater risk of presenting LVNC when compared to controls (Chin and Jenni criteria). No other CHD presented similar risk. Current results show some agreement with previous studies, such as LVNC morphology being more prevalent in VSDs. Nonetheless, this is a morphological study and cannot be correlated with symptoms or severity of the CHD.
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Piga, Antonio, Filomena Longo, Khaled M. Musallam, Andrea Veltri, Lia Davicino, and Rodolfo Bonamini. "Prevalence and Risk Factors of Left Ventricular Noncompaction in Patients with β-Thalassemia." Blood 120, no. 21 (November 16, 2012): 2127. http://dx.doi.org/10.1182/blood.v120.21.2127.2127.
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Abstract Abstract 2127 Left ventricular noncompaction (LVNC) is a rare cardiomyopathy with potentially serious outcomes. It results in multiple and excessive trabeculations, deep intertrabecular recesses, and a thickened ventricular myocardium with two distinct layers, compacted and noncompacted. The condition is most commonly congenital although acquired forms have been described. A recent report of LVNC detected in a β-thalassemia twin suggested an association with cardiac siderosis. In a cross-sectional study of 135 transfusion-dependent β-thalassemia patients (130 major and 5 intermedia, mean age 29.6 ± 7.7 year, 49.6% males) presenting for cardiac iron assessment by magnetic resonance imaging (MRI), we evaluated the prevalence and risk factors for LVNC. None of the patients had neuromuscular or congenital heart disease. Eighteen patients (13.3%, 95% CI: 8.6–20.1) fulfilled the pre-assigned strict criteria for LVNC on cardiac MRI. There were no statistically significant differences between patients with and without LVNC in respect to: demographics; hemoglobin levels; splenectomy status; systemic, hepatic and cardiac iron overload indices; hepatic disease and infection studies; or iron chelator type. Patients with LVNC were more likely to have heart failure (adjusted OR: 1.77, 95% CI: 0.29 to 10.89); although with high uncertainty. Patients with β-thalassemia have a higher prevalence of LVNC than normal individuals. As this finding could not be explained by conventional risk factors in this patient population, further investigating of the underlying mechanisms of LVNC is warranted. This remains crucial for an entity with adverse cardiac outcomes, especially in a β-thalassemia patients where cardiac disease remains a primary cause of mortality. Disclosures: No relevant conflicts of interest to declare.
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Palm, D., N. Knuckey, M. Guglielmo, P. Watson, M. Primiano, and C. Johanson. "Choroid plexus electrolytes and ultrastructure following transient forebrain ischemia." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 269, no. 1 (July 1, 1995): R73—R79. http://dx.doi.org/10.1152/ajpregu.1995.269.1.r73.
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A temporal profile of lateral and fourth ventricle rat choroid plexus (LVCP and 4VCP, respectively) tissue injury and recovery was determined using alterations in K, Na, and H2O content and ultrastructure after 10 min of transient forebrain ischemia (TFI). At 0.5 h postischemia the LVCP displayed a maximum reduction in K content by 32% and a significant increase in Na content by 85% and H2O content by 22%. LVCP tissue K, Na, and H2O content returned to sham values by 24 h postischemia. Ultrastructural changes appeared more severe between 0.5 and 12 h postischemia, whereas by 24 h, normal ultrastructure was restored. Elevations in 4VCP tissue Na (P < 0.05) and H2O content, which were less than those in LVCP, gradually reached a maximum by 24 h compared with sham. No change in 4VCP tissue ultrastructure was observed. These results indicate that the LVCP tissue is more vulnerable than 4VCP in the bilateral carotid artery occlusion model but that it recovers in a timely manner after TFI. Furthermore, the ability of the LVCP tissue to rapidly recover suggests its functional importance in helping to restore brain homeostasis.
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Malla, R., Ranjit Sharma, B. Rauniyar, M. B. KC, A. Maskey, D. Joshi, and S. Hamal. "Left Ventricular Noncompaction." Journal of Nepal Medical Association 48, no. 174 (April 1, 2009): 180–4. http://dx.doi.org/10.31729/jnma.241.
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Left Ventricular Noncompaction(LVNC) is a genetic cardiac disease of emerging importance with a distinct clinical and pathophysiological presentation. The most common clinical manifestations include heart failure,arrhythmias and embolic events, and in children it may be associatedwith facial dysmorphisms and Wolff–Parkinson–Whitesyndrome. The diagnosis of LVNC, however, is often missed, most often as a consequence of ignorance of the condition. Echocardiography is considered the reference standard for the diagnosis of LVNC. Prognosis remains poor for patients with impaired systolic left ventricular function, as treatment options are very limited. Because of the familial association of LVNC, fi rst-degree relatives should be screened by Echocardiography.Key Words: heart, left ventricle, noncompaction
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Nikolic, Aleksandra, Ljiljana Jovovic, Slobodan Tomic, and Milan Vukovic. "Left ventricular noncompaction: Clinical-echocardiographic study." Vojnosanitetski pregled 69, no. 1 (2012): 32–36. http://dx.doi.org/10.2298/vsp1201032n.
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Background/Aim. Left ventricular noncompaction (LVNC) is a disorder in endomyocardial morphogenesis, seen either isolated (in the absence of other cardiac anomalies) or in association with congenital heart disease and some neuromuscular diseases. Intrauterine arrest of the compaction of myocardial fibers is postulated to be the reason of LVNC. Recognition of this condition is extremely important due to its high mortality and morbidity that lead to progressive heart failure, ventricular arrhythmias and thromboembolic events. The aim of this study was to determine the prevalence and clinical presentation of LVNC among consecutive outpatients according to clinical and echocardiographyic findings. Methode. A total of 3,854 consecutive patients examined at the Institute for Cardiovascular Diseases within a period January 2006 - January 2007 were included in the study. All the patients underwent echocardiographic examination using the same equipment (Vivid 7, GE Medical System). Echocardiographic parameters and clinical presentation in patients with echocardiographic criteria for LVNC were analyzed. Results. Analyzing 3,854 consecutive outpatients, using two-dimensional Color Doppler echocardiography from January 2006 to January 2007, 12 patients met the criteria for LVNC. Seven of them were male. The mean age at diagnosis was 45 ? 15 years. Analyzing clinical manifestation of LVNC it was found that seven patients had signs of heart failure, six had arrhythmias with no embolic events. Conclusion. Our results suggest that the real prevalence of LVNC may be higher than expected. New studies have to be done to solve this problem.
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Rácz, Anita. "«Aportar contribución», «experimentar cambios» – Las construcciones con verbo soporte en el español y en el alemán." Acta Hispanica 18 (January 1, 2013): 139–48. http://dx.doi.org/10.14232/actahisp.2013.18.139-148.
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This essay gives an overview about the so called 'light verb constructions' (LVCs) of the Spanish and German languages. LVCs are formed by the combination of a noun as the semantic, and a verb as the syntactic head of the construction. Since the descprition of their Spanish equivalents has gained attention only recently, we consider it important to adapt and apply the findings of the thorough German experiments on Spanish LVCs.
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Deng, Ling Hui, Zhi Xin Wang, and Jian Min Duan. "Protection Scheme for DC Microgrid Distribution System." Advanced Materials Research 614-615 (December 2012): 1661–65. http://dx.doi.org/10.4028/www.scientific.net/amr.614-615.1661.
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The low voltage DC (LVDC) distribution system is a new concept and a promising technology to be used in the future smart distribution system having high level cost-efficiency and reliability. In this paper, a low-voltage (LV) DC microgrid protection system design is proposed. Usually, an LVDC microgrid must be connected to an ac grid through converters with bidirectional power flow and, therefore, a different protection scheme is needed. This paper describes practical protection solutions for the LVDC network and an LVDC system laboratory prototype is being experimentally tested by MATLAB/SIMULINK. The results show that it is possible to use available devices to protect such a system. But other problems may arise which needs further study.
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Lorca, Rebeca, María Martín, Isaac Pascual, Aurora Astudillo, Beatriz Díaz Molina, Helena Cigarrán, Elías Cuesta-Llavona, et al. "Characterization of Left Ventricular Non-Compaction Cardiomyopathy." Journal of Clinical Medicine 9, no. 8 (August 5, 2020): 2524. http://dx.doi.org/10.3390/jcm9082524.
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Left ventricle non-compaction cardiomyopathy (LVNC) has gained great interest in recent years, being one of the most controversial cardiomyopathies. There are several open debates, not only about its genetic heterogeneity, or about the possibility to be an acquired cardiomyopathy, but also about its possible overdiagnosis based on imaging techniques. In order to better understand this entity, we identified 38 LVNC patients diagnosed by cardiac MRI (CMRI) or anatomopathological study that could underwent NGS-sequencing and clinical study. Anatomopathological exam was performed in eight available LVNC hearts. The genetic yield was 34.2%. Patients with negative genetic testing had better left ventricular ejection fraction (LVEF) or it showed a tendency to improve in follow-up, and a possible trigger factor for LVNC was identified in 1/3 of them. Nonetheless, cerebrovascular accidents occurred in similar proportions in both groups. We conclude that in LVNC there seem to be different ways to achieve the same final phenotype. Genetic testing has a good genetic yield and provides valuable information. LVNC without an underlying genetic cause may have a better prognosis in terms of LVEF evolution. However, anticoagulation to prevent cerebrovascular accident (CVA) should be carefully evaluated in all patients. Larger series with pathologic examination are needed to help better understand this entity.
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Ross, Samantha B., Katherine Jones, Bianca Blanch, Rajesh Puranik, Kevin McGeechan, Alexandra Barratt, and Christopher Semsarian. "A systematic review and meta-analysis of the prevalence of left ventricular non-compaction in adults." European Heart Journal 41, no. 14 (May 29, 2019): 1428–36. http://dx.doi.org/10.1093/eurheartj/ehz317.
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Abstract Aims To assess the reported prevalence of left ventricular non-compaction (LVNC) in different adult cohorts, taking in to consideration the role of diagnostic criteria and imaging modalities used. Methods and results A systematic review and meta-analysis of studies reporting LVNC prevalence in adults. Studies were sourced from Pre-Medline, Medline, and Embase and assessed for eligibility according to inclusion criteria. Eligible studies provided a prevalence of LVNC in adult populations (≥12 years). Studies were assessed, and data extracted by two independent reviewers. Fifty-nine eligible studies documenting LVNC in 67 unique cohorts were included. The majority of studies were assessed as moderate or high risk of bias. The pooled prevalence estimates for LVNC were consistently higher amongst cohorts diagnosed on cardiac magnetic resonance (CMR) imaging (14.79%, n = 26; I2 = 99.45%) compared with echocardiogram (1.28%, n = 36; I2 = 98.17%). This finding was unchanged when analysis was restricted to studies at low or moderate risk of bias. The prevalence of LVNC varied between disease and population representative cohorts. Athletic cohorts demonstrated high pooled prevalence estimates on echocardiogram (3.16%, n = 5; I2 = 97.37%) and CMR imaging (27.29%, n = 2). Conclusion Left ventricular non-compaction in adult populations is a poorly defined entity which likely encompasses both physiological adaptation and pathological disease. There is a higher prevalence with the introduction of newer imaging technologies, specifically CMR imaging, which identify LVNC changes more readily. The clinical significance of these findings remains unclear; however, there is significant potential for overdiagnosis, overtreatment, and unnecessary follow-up.
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Simon, Marcel, Lars Harbaum, Tim Oqueka, Stefan Kluge, and Hans Klose. "Endoscopic lung volume reduction coil treatment in patients with chronic hypercapnic respiratory failure: an observational study." Therapeutic Advances in Respiratory Disease 11, no. 1 (October 27, 2016): 9–19. http://dx.doi.org/10.1177/1753465816676222.
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Background: Endoscopic lung volume reduction coil (LVRC) treatment is an option for selected patients with severe emphysema. In the advanced stages, emphysema leads to respiratory failure: hypoxemia and eventually chronic hypercapnic respiratory failure. It can be hypothesized that LVRC treatment, a procedure targeting hyperinflation and thereby reducing ventilatory workload, may be especially beneficial in patients with chronic hypercapnic respiratory failure. This study was conducted to gain first insights into the effects and the safety of LVRC treatment in patients with emphysema and chronic hypercapnic respiratory failure. Methods: A retrospective observational study conducted in the Department of Respiratory Medicine at the University Medical Center Hamburg-Eppendorf, Germany on all patients with chronic hypercapnic respiratory failure in whom bilateral LVRC treatment was performed between 1 April 2012 and 30 September 2015. Results: During the study period, bilateral LVRC treatment was performed in 10 patients with chronic hypercapnic respiratory failure. Compared with baseline, bilateral LVRC treatment led to a significant increase in mean forced expiratory volume in one second (FEV1) from 0.5 ± 0.1 l to 0.6 ± 0.2 l ( p = 0.004), a decrease in residual volume (RV) from 6.1 ± 0.9 l to 5.6 ± 1.1 l ( p = 0.02) and a reduction in partial pressure of carbon dioxide in arterial blood (PaCO2) from 53 ± 5 mmHg to 48 ± 4 mmHg ( p = 0.03). One case of hemoptysis requiring readmission to hospital was the only severe adverse event. Conclusions: LVRC treatment was safe and effective in patients with nonsevere chronic hypercapnic respiratory failure. It led not only to an improvement in lung function but also to a significant decrease in PaCO2.
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Kim, Soo-Hwan, Gyu-Wan Choi, Jong-Fil Moon, Tae-Hoon Kim, and Ju-Yong Kim. "A Study on the Fault Analysis of the LVDC Using PSCAD/EMTDC." Transactions of the Korean Institute of Electrical Engineers P 65, no. 3 (September 1, 2016): 219–23. http://dx.doi.org/10.5370/kieep.2016.65.3.219.
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Cerar, Andraž, Juš Kšela, Gregor Poglajen, Bojan Vrtovec, and Ivan Kneževič. "LVAD as a Bridge to Heart Transplantation in a Patient with Left Ventricular Noncompaction Cardiomyopathy and Advanced Heart Failure." Heart Surgery Forum 19, no. 3 (June 24, 2016): 128. http://dx.doi.org/10.1532/hsf.1563.
Full textAbstract:
Left ventricular noncompaction cardiomyopathy (LVNC) is a rare hereditary cardiomyopathy characterized by the formation of an outer compacted and inner noncompacted layer of the myocardium. The latter is characterized by prominent trabeculations and deep intertrabecular recesses and is functionally inferior to the compacted myocardium. As there is no specific treatment for patients with LVNC who develop heart failure, the management of these patients is limited and many patients progress to advanced stages of the disease. For LVNC patients with advanced heart failure, the data regarding the use of mechanical circulatory support are scarce. We report a case of a 29-year-old patient with LVNC and advanced refractory heart failure, who was successfully bridged to heart transplantation using a long-term continuous-flow left ventricular assist device.
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Myasnikov, R. P., A. A. Bukaeva, O. V. Kulikova, A. I. Ershova, A. V. Petukhova, E. D. Zotova, A. N. Meshkov, et al. "New variant of PRDM16 gene nucleotide sequence in a family with various phenotypic manifestations of the non-compacted myocardium." Russian Journal of Cardiology 26 (April 22, 2021): 4315. http://dx.doi.org/10.15829/1560-4071-2021-4315.
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The article presents the examination of three generations of a family with diagnosed left ventricular noncompaction (LVNC) and various phenotypic manifestations of the disease (isolated, hypertrophic and dilated type of LVNC). As a result of a molecular genetics tests, a previously undescribed single nucleotide deletion in the PRDM16 gene was revealed in all family members with the LVNC phenotype, leading to a frameshift mutation in exon 9 and the formation of a premature termination codon. This gene encodes a transcription factor responsible for after-birth suppressing the expression of genes involved in prenatal and postnatal development. Despite the presence of previous studies showing the relationship of the PRDM16 gene with LVNC development, currently there are insufficient data to prove the pathogenicity of the identified variant. However, the segregation of the symptomatic variant in three generations supports the association of the identified variant with LVNC. With the accumulation of information about changes in PRDM16 in patients with cardiomyopathies, it is possible to change the status of this gene and clarify its contribution to primary heart diseases.
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Ding, Haigang, Jiyun Zhao, Gang Cheng, Steve Wright, and Yufeng Yao. "The Influence of Valve-Pump Weight Ratios on the Dynamic Response of Leaking Valve-Pump Parallel Control Hydraulic Systems." Applied Sciences 8, no. 7 (July 22, 2018): 1201. http://dx.doi.org/10.3390/app8071201.
Full textAbstract:
A new leaking valve-pump parallel control (LVPC) oil hydraulic system is proposed to improve the performance of dynamic response of present variable speed pump control (VSPC) system, which is an oil hydraulic control system with saving energy. In the LVPC, a control valve is operating at leaking status, together with a variable speed pump, to regulate the system flow of hydraulic oil simultaneously. Therefore, the degree of valve control and pump control can be adjusted by regulating the valve-pump weight ratio. The LVPC system design, mathematical model development, system parameter and control performance analysis are carried out systematically followed by an experimental for validation process. Results have shown that after introducing the valve control, the total leakage coefficient increases significantly over a wide range with the operating point and this further increases damping ratios and reduces the velocity stiffness. As the valve-pump weight ratio determines the flow distribution between the valve and the pump and the weight factors of the valve and/or the pump controls determines the response speed of the LVPC system, thus if the weight factors are constrained properly, the LVPC system will eventually have a large synthetic open-loop gain and it will respond faster than the VSPC system. The LVPC will enrich the control schemes of oil hydraulic system and has potential value in application requiring of fast response.
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Mershina, E. A., O. V. Kulikova, R. P. Myasnikov, E. A. Lukina, A. N. Meshkov, A. V. Kiseleva, P. S. Pilyus, et al. "The non-compacted myocardium in patients with hemochromatosis: a phenomenon or cardiopathy? The role of magnetic resonance imaging and molecular genetics in diagnosis." Russian Journal of Cardiology 25, no. 4 (May 11, 2020): 3759. http://dx.doi.org/10.15829/1560-4071-2020-3759.
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This article presents the results of studies on high prevalence of left ventricular noncompaction (LVNC) in patients with secondary hemochromatosis (SH). We also included case reports of patients with SH and LVNC and compared imaging data using modified modern criteria for LVNC and molecular genetic testing (MGT). In patients with cardiac hemochromatosis, left ventricular noncompaction is noted, the nature of which is most likely secondary. In order to confirm this hypothesis, a prospective observational study, including family screening and MGT, is required.
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Balla, Cristina, Martina De Raffele, Maria Angela Deserio, Mariabeatrice Sanchini, Marianna Farnè, Cecilia Trabanelli, Luca Ragni, et al. "Left Ventricular Myocardial Noncompaction with Advanced Atrioventricular Conduction Disorder and Ventricular Arrhythmias in a Young Patient: Role of MIB1 Gene." Journal of Cardiovascular Development and Disease 8, no. 9 (September 9, 2021): 109. http://dx.doi.org/10.3390/jcdd8090109.
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Left ventricular noncompaction (LVNC) is a structural abnormality of the left ventricle, usually described as an isolated condition, or sometimes associated with other structural cardiac diseases. LVNC is generally asymptomatic, although it may present conduction disorders, arrhythmias, and heart failure. Here, we present the case of a patient who came to our attention with a severe LVNC phenotype associated with advanced AV conduction disorder, and supraventricular and ventricular arrhythmias at young age, in which a novel MIB1, likely pathogenic, variation has been identified.
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Hasnat, Mohammad Abul, Md Israrul Hossain, Md Abdullahel Kafee, and Md Borhan Uddin. "Left Ventricular Noncompaction Cardiomyopathy (LVNC) with Left Ventricular Apical Thrombus– A Case Study." Journal of Armed Forces Medical College, Bangladesh 13, no. 1 (April 23, 2017): 128–30. http://dx.doi.org/10.3329/jafmc.v13i1.41072.
Full textAbstract:
Left ventricular non-compaction (LVNC) is a rare congenital cardiomyopathy, with or without LV dysfunction, characterized by prominent trabeculations and associated deep recesses which communicate with the ventricular cavity rather than the coronary circulation. LVNC affects all age groups and can occur in isolation or association with other cardiac and systemic anomalies, especially with neuromuscular disorders. Patient may be asymptomatic or present with ventricular arrhythmias, thromboembolism, heart failure and sudden cardiac death. Echocardiography is the most common tool for diagnosis of LVNC. Contrast ventriculography, computed tomography (CT) and magnetic resonance imaging (MRI) are other useful diagnostic tools. Due to increasing awareness and improvement in imaging methods, LVNC is being diagnosed frequently in patients now a day.
Journal of Armed Forces Medical College Bangladesh Vol.13(1) 2017: 128-130