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1

Chen, Shen Li, and Chun Ju Lin. "Evaluation of ESD/LU Reliabilities by Different SCR Layout Types in a 0.35μm 3.3V CMOS Process." Advanced Materials Research 779-780 (September 2013): 1124–29. http://dx.doi.org/10.4028/www.scientific.net/amr.779-780.1124.

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This paper aimed at the evaluation of layout dependence on ESD/LU reliabilities in the 0.35μm 3.3V low-voltage triggered silicon-controlled-rectifier (LVTSCR) DUTs. In this work, the parameter of channel L in a pMOS and the parameter S of an SCR are varied to study the influence on trigger voltage (Vt1), holding voltage (Vh) and secondary breakdown current (It2), respectively. Eventually, it can be found that the layout illustration of type-2 has a higher It2than that of type-1, i.e., the ratio of (It2)type-2/(It2)type-1> 3 among all the LVTpSCRs. Meanwhile, the holding voltage of all SCR devices are latch-up free while operated at 3.3V. Therefore, the type-2 layouts of SCR devices are so excellent structure in the ESD/LU reliability considerations for this 0.35μm 3.3V CMOS process.
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2

Chen, Shen Li, and Der Ann Fran. "Implementation of ESD Protection for Output Driver ICs with SCR Circuits Techniques." Applied Mechanics and Materials 464 (November 2013): 139–44. http://dx.doi.org/10.4028/www.scientific.net/amm.464.139.

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In this paper, an output driver which drove a large current in DC brushless fan ICs was taken for the HBM ESD stress. The protection circuits of this IC were also designed to improve ESD robustness by various layout parameters and structures. From the ESD testing results, it was found that the positive Pad-to-VSS (PS) zapping mode was weakest for the output driver of DC brushless fan ICs during ESD stress. Eventually, protection circuits with a complementary low-voltage-triggered SCR (LVTSCR) were used to protect the whole-chip ESD stress. After a systematic improvement, an SCR structure of adding protection circuits can effectively protect the whole-chip ESD reliability, as compared with the original DUT; the ESD failure threshold (VESD) of PS mode is increased 314% in a best structure when an LVTSCR with the drain-tap S space is 4μm.
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3

Li, Li, Hongxia Liu, Cui Dong, and Wen Zhou. "Characterization analysis of UDSM LVTSCR under TLP stress." Journal of Semiconductors 32, no. 5 (May 2011): 054002. http://dx.doi.org/10.1088/1674-4926/32/5/054002.

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4

Ming-Dou Ker, Chung-Yu Wu, and Hun-Hsien Chang. "Complementary-LVTSCR ESD protection circuit for submicron CMOS VLSI/ULSI." IEEE Transactions on Electron Devices 43, no. 4 (April 1996): 588–98. http://dx.doi.org/10.1109/ted.1996.1210725.

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5

Vashchenko, V., A. Concannon, M. ter Beek, and P. Hopper. "LVTSCR structures for latch-up free ESD protection of BiCMOS RF circuits." Microelectronics Reliability 43, no. 1 (January 2003): 61–69. http://dx.doi.org/10.1016/s0026-2714(02)00125-7.

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6

Zhu, Ling, Hai-Lian Liang, Xiao-Feng Gu, and Jie Xu. "Design of a novel high holding voltage LVTSCR with embedded clamping diode." Chinese Physics B 29, no. 6 (June 2020): 068503. http://dx.doi.org/10.1088/1674-1056/ab836e.

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7

Lee, Joo-Young. "Analysis of SCR, MVSCR, LVTSCR With I-V Characteristic and Turn-On-Time." Journal of IKEEE 20, no. 3 (September 30, 2016): 295–98. http://dx.doi.org/10.7471/ikeee.2016.20.3.295.

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8

Guilhaume, A., P. Galy, JP Chante, B. Foucher, and F. Blanc. "Simulation and experimental comparison of GGNMOS and LVTSCR protection cells under ElectroStatic Discharges." Microelectronics Reliability 41, no. 9-10 (September 2001): 1433–37. http://dx.doi.org/10.1016/s0026-2714(01)00175-5.

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9

Vashchenko, V. A., A. Concannon, M. terBeek, and P. Hopper. "High Holding Voltage Cascoded LVTSCR Structures for 5.5-V Tolerant ESD Protection Clamps." IEEE Transactions on Device and Materials Reliability 4, no. 2 (June 2004): 273–80. http://dx.doi.org/10.1109/tdmr.2004.826584.

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10

Li, Li, and Hongxia Liu. "A novel double-trench LVTSCR used in the ESD protection of a RFIC." Journal of Semiconductors 32, no. 10 (October 2011): 104005. http://dx.doi.org/10.1088/1674-4926/32/10/104005.

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11

Zhou, Zijie, Xiangliang Jin, Yang Wang, Peng Dong, Yan Peng, and Jun Luo. "Analysis of Non-Uniform Current Distribution in Multi-Fingered and Low-Voltage-Triggered LVTSCR." Elektronika ir Elektrotechnika 27, no. 1 (February 25, 2021): 41–47. http://dx.doi.org/10.5755/j02.eie.25352.

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Laterally Diffused Metal Oxide Semiconductor Silicon-Controlled Rectifier (LDMOS-SCR) is usually used in Electrostatic Discharge (ESD) protection. LDMOS-SCR discharges current by parasitic SCR, but the MOS in it cannot work when parasitic SCR is stabilized. To further enhance the Electrostatic Discharge (ESD) discharging capability of LDMOS-SCR, a novel high failure current LDMOS-SCR with 12 V operation voltage is fabricated and verified in a 0.18-um high-voltage Bipolar-CMOS-DMOS (BCD) process. Compared with conventional LDMOS-SCR, the novel LDMOS-SCR (LDMOS-SCR-R) introduced a heavily doped p-type region, which is located between the heavily doped n-type and p-type regions of Cathode and is connected with the gate. The adding p-well resistance can drop the voltage on the gate, and the gate with p-well resistance also has resistance and capacitance coupling effect. According to the results of the transmission line pulse test (TLP), the voltage applied to the gate by increasing the p-well resistance plays a major role in the device working mechanism. Under the same device size, LDMOS-SCR-R has higher It2 (8.6 A) than conventional LDMOS (2.21 A) or LDMOS-SCR (6.62 A) in TLP results. Compared with LDMOS-SCR, the failure current of LDMOS-SCR-R increases by 30 %, and the FOM of LDMOS-SCR-R increases by 34 %. The response of LDMOS-SCR-R is also faster than that of LDMOS-SCR under larger current conditions. In addition, the phenomenon in TLP results is consistent with simulation results. The proposed LDMOS-SCR-R can effectively increase failure current without affecting the device’s design window, and the additional p-type region will not increase the layout area.
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12

Ker, M. D. "ESD protection for CMOS output buffer by using modified LVTSCR devices with high trigger current." IEEE Journal of Solid-State Circuits 32, no. 8 (1997): 1293–96. http://dx.doi.org/10.1109/4.604093.

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13

Ker, Ming-Dou, and Hun-Hsien Chang. "Cascoded LVTSCR with tunable holding voltage for ESD protection in bulk CMOS technology without latchup danger." Solid-State Electronics 44, no. 3 (March 2000): 425–45. http://dx.doi.org/10.1016/s0038-1101(99)00247-6.

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14

Guilhaume, A., P. Galy, J. P. Chante, B. Foucher, S. Bardy, and F. Blanc. "ESD evaluation of a low voltage triggering SCR (LVTSCR) device submitted to transmission line pulse (TLP) test." Journal of Electrostatics 56, no. 3 (October 2002): 281–94. http://dx.doi.org/10.1016/s0304-3886(02)00092-x.

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15

Ker, Ming-Dou, and Hun-Hsien Chang. "How to safely apply the LVTSCR for CMOS whole-chip ESD protection without being accidentally triggered on." Journal of Electrostatics 47, no. 4 (October 1999): 215–48. http://dx.doi.org/10.1016/s0304-3886(99)00037-6.

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16

Chen, Rui-Bo, Hong-Xia Liu, Dan Guo, Wei Huang, Xiao-Zong Huang, and Zhiwei Liu. "A latch-up-free LVTSCR with improved overshoot characteristic for ESD protection in 40 nm CMOS process." Semiconductor Science and Technology 36, no. 6 (May 26, 2021): 065025. http://dx.doi.org/10.1088/1361-6641/abf3a9.

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17

Boileau, Catherine. "The Laboratory for Vascular Translational Science (LVTS)." European Heart Journal 41, no. 31 (August 14, 2020): 2928–31. http://dx.doi.org/10.1093/eurheartj/ehaa256.

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18

Mhamdi, Zeineb, Hugues Fausther-Bovendo, Olus Uyar, Julie Carbonneau, Marie-Christine Venable, Yacine Abed, Gary Kobinger, Guy Boivin, and Mariana Baz. "Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus." Microorganisms 8, no. 12 (December 11, 2020): 1968. http://dx.doi.org/10.3390/microorganisms8121968.

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The prolonged treatment of immunosuppressed (IS) individuals with anti-influenza monotherapies may lead to the emergence of drug-resistant variants. Herein, we evaluated oseltamivir and polymerase inhibitors combinations against influenza A/H3N2 infections in an IS mouse model. Mice were IS with cyclophosphamide and infected with 3 × 103 PFU of a mouse-adapted A/Switzerland/9715293/2013 (H3N2) virus. Forty-eight hours post-infection, the animals started oseltamivir, favipiravir or baloxavir marboxil (BXM) as single or combined therapies for 10 days. Weight losses, survival rates and lung viral titers (LVTs) were determined. The neuraminidase (NA) and polymerase genes from lung viral samples were sequenced. All untreated animals died. Oseltamivir and favipiravir monotherapies only delayed mortality (the mean day to death (MDD) of 21.4 and 24 compared to 11.4 days for those untreated) while a synergistic improvement in survival (80%) and LVT reduction was observed in the oseltamivir/favipiravir group compared to the oseltamivir group. BXM alone or in double/triple combination provided a complete protection and significantly reduced LVTs. Oseltamivir and BXM monotherapies induced the E119V (NA) and I38T (PA) substitutions, respectively, while no resistance mutation was detected with combinations. We found that the multiple dose regimen of BXM alone provided superior benefits compared to oseltamivir and favipiravir monotherapies. Moreover, we suggest the potential for drug combinations to reduce the incidence of resistance.
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19

Smith, Aisling, Neidin Bussmann, Phillip Levy, Orla Franklin, Naomi McCallion, and Afif EL-Khuffash. "Comparison of left ventricular rotational mechanics between term and extremely premature infants over the first week of age." Open Heart 8, no. 1 (January 2021): e001458. http://dx.doi.org/10.1136/openhrt-2020-001458.

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ObjectiveLeft ventricle (LV) rotational mechanics is an emerging tool to characterise LV function, but warrants further evaluation in neonates. The aim of this study was to compare LV rotational mechanics between term and extremely preterm babies over the first week of age.MethodsIn this prospective study, we serially assessed LV rotational parameters in 50 term infants and compared them with a historical dataset of 50 preterm infants born <29 weeks gestation. LV basal and apical rotation, LV twist, LV twist/untwist rate and torsion were derived using two-dimensional speckle tracking echocardiography at three time points over the first week of age.ResultsThere was no change in LV twist, LV torsion, basal rotation or apical rotation in term infants over the study period (all p>0.05). LV twist and torsion were higher in preterm infants, and increased over time. In preterm infants, basal rotation evolved from anticlockwise to clockwise rotation. Apical rotation remained anticlockwise in both groups (all p>0.05). LV twist rate (LVTR) and untwist rate was higher in preterm infants and increased over the three time points (all p>0.05). There was a strong positive correlation between LV torsion and LV untwist rate (LVUTR) in the entire cohort during the third scan.ConclusionTerm infants exhibit minimal LV twist which remains unchanged over the first week of age. This is in contrast to premature infants who demonstrate increasing indices of twist, torsion, LVTR and LVUTR over the first week, likely as a compensatory mechanism for reduced LV compliance.
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20

Lee, Byeong-Ryul, and Hae-Bum Choi. "A Comparative Study between the CHAPS of England and The LVTS of Canada." Korea International Trade Research Institute 13, no. 2 (April 30, 2017): 395–408. http://dx.doi.org/10.16980/jitc.13.2.201704.395.

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21

Talle, Mohammed Abdullahi, Faruk Buba, and Charles Oladele Anjorin. "Prevalence and Aetiology of Left Ventricular Thrombus in Patients Undergoing Transthoracic Echocardiography at the University of Maiduguri Teaching Hospital." Advances in Medicine 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/731936.

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Objectives. We sought to determine the prevalence and aetiology of LVT among patients undergoing echocardiography.Methods. We reviewed case notes and echocardiographic data of patient diagnosed with LVT using noncontrast transthoracic echocardiography. Definition of various conditions was made using standard guidelines. Mean ± SD were derived for continuous variables and comparison was made using Student’st-test.Results. Total of 1302 transthoracic echocardiograms were performed out of which 949 adult echocardiograms were considered eligible. Mean age of all subjects with abnormal echocardiograms was 44.73 (16.73) years. Abnormalities associated with LVT were observed in 782/949 (82.40%) subjects among whom 84/782 (8.85%) had LVT. The highest prevalence of 39.29% (33/84) was observed in patients with dilated cardiomyopathy, followed by myocardial infarction with a prevalence of 29.76% (25/84). Peripartum cardiomyopathy accounted for 18/84 (21.43%) cases with some having multiple thrombi, whereas hypertensive heart disease was responsible for 6/84 (7.14%) cases. The lowest prevalence of 2.38% (2/84) was observed in those with rheumatic heart disease. Left ventricular EF of <35% was recorded in 55/84 (65.48%).Conclusions. Left ventricular thrombus is common among patients undergoing echo, with dilated cardiomyopathy being the most common underlying aetiology followed by myocardial infarction. Multiple LVTs were documented in peripartum cardiomyopathy.
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22

Zeng, Zhiping, Jundong Wang, Huatuo Yin, Shiwen Shen, Abdulmumin Ahmed Shuaibu, and Weidong Wang. "Experimental Investigation on the Vibration Reduction Characteristics of an Optimized Heavy-Haul Railway Low-Vibration Track." Shock and Vibration 2019 (February 25, 2019): 1–17. http://dx.doi.org/10.1155/2019/1539564.

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Heavy-haul railway has been developed rapidly in many countries in the world due to its great social and economic benefits. One of the key technologies for heavy-haul railway is the reduction of vibration on the track structures and its surrounding due to impact load induced by the train in service. The vibration behaviors of two kinds of low-vibration track (LVT) systems for heavy-haul railway are investigated in this paper. Firstly, two indoor full-scale low-vibration track models (new LVT and traditional LVT), which include rail, fastener, bearing block, rubber boot, track slab, and foundation base, were constructed according to design drawings. Secondly, the vibration responses of the different track components under the impact excitation of a dropping wheelset were measured. Thirdly, the time-domain characteristics of each track component of the two LVTs were compared by the acquired vibration time-history curves. Finally, the frequency-domain distribution was analyzed, and the vibration reduction performance was evaluated by the comprehensive time-frequency analysis results. The results show the new LVT has lower vibration acceleration, shorter duration of vibration period, lower vibration frequency of track components, and most importantly an obvious vibration reduction effect on the ground. The research results are useful to further optimize the design of LVT to reduce the vibration under train impact load.
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23

Chen, Ruibo, Hongxia Liu, Wenqiang Song, Feibo Du, Hao Zhang, Jikai Zhang, and Zhiwei Liu. "Robust and Latch-Up-Immune LVTSCR Device with an Embedded PMOSFET for ESD Protection in a 28-nm CMOS Process." Nanoscale Research Letters 15, no. 1 (November 11, 2020). http://dx.doi.org/10.1186/s11671-020-03437-3.

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Abstract Low-voltage-triggered silicon-controlled rectifier (LVTSCR) is expected to provide an electrostatic discharge (ESD) protection for a low-voltage integrated circuit. However, it is normally vulnerable to the latch-up effect due to its extremely low holding voltage. In this paper, a novel LVTSCR embedded with an extra p-type MOSFET called EP-LVTSCR has been proposed and verified in a 28-nm CMOS technology. The proposed device possesses a lower trigger voltage of ~ 6.2 V and a significantly higher holding voltage of ~ 5.5 V with only 23% degradation of the failure current under the transmission line pulse test. It is also shown that the EP-LVTSCR operates with a lower turn-on resistance of ~ 1.8 Ω as well as a reliable leakage current of ~ 1.8 nA measured at 3.63 V, making it suitable for ESD protections in 2.5 V/3.3 V CMOS processes. Moreover, the triggering mechanism and conduction characteristics of the proposed device were explored and demonstrated with TCAD simulation.
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24

Nakaboh, Ayumi, Akiko Goda, Shinji Nakao, Katsumi Oka, Takeshi Tsujino, Masao Yuba, Misato Otsuka, et al. "Abstract 5734: Left Ventricular Torsion Reflects Degree of Myocardial Fibrosis in Hypertrophic Cardiomyopathy." Circulation 118, suppl_18 (October 28, 2008). http://dx.doi.org/10.1161/circ.118.suppl_18.s_992-a.

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Background : LV torsion (LVtor) is reduced in patients with impaired LV systolic function, e.g., dilated cardiomyophaty. It used to be thought that LVtor is reduced in patients with hypertrophic caridiomyopathy (HCM) because of the myocardial disarray; however, recent observation showed that LVtor assessed with tagged magnetic resonance imaging (MRI) even increased in patients with HCM. Recently LVtor is assessable with novel ultrasound speckle tracking imaging (STI) method. This technique may be used to assess intra-ventricular torsion in the LV muscle (intra-LVtor) that occurs due to the different fiber directions between the endocardium and epicardium. In this study, we analyzed LVtor and intra-LVtor in light of LV fibrosis in patients with HCM. Methods : MRI and echo studies were performed in 10 patients with HCM in whom any medication had not been given to HCM. MRI was used to determine LV mass index. In addition, %DEmass was determined as an MRI index of the extent of myocardial fibrosis by dividing the extent of late gadolinium enhancement by LV mass. We acquired basal and apical short-axis LV images with 2D echocardiography for off-line STI analysis to determine LVtor and intra-LVtor. We traced 18 points of the endcardium and epicardium, respectively, and averaged all regional rotation at the basal and apical plane, respectively. LVtor was defined as the difference of LV rotation between the basal and apical plane. Intra-LVtor was defined as the difference in the rotation between the endcardium and epicardium. Results : There was a significant correlation between %DEmass and LVtor(r=−0.72, p<0.05, indicating that LVtor is reduced in HCM patients with larger extent of LV myocardial fibrosis. There was no significant correlation between LVtor and LV mass index (r=−0.15, p=n.s.). %DEmass also correlated with intra-LVtor (r=−0.67, p<0.05, indicating that intra-LVtor is reduced in HCM patients with larger extent of LV myocardial fibrosis. Conclusions : Both LV torsion and intra-LV torsion are reduced in HCM patients with extended LV fibrosis. In other words, the extent of myocardial fibrosis may be assessed with LVtor and intra-LVtor by use of speckle tracking imaging in patients with HCM.
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25

Wang, Chuanqi, Lingwei Ruan, Hong Shi, Wenyang Lin, Linmin Liu, and Sujie Li. "Phosphorylation of Shrimp Tcf by a Viral Protein Kinase WSV083 Suppresses Its Antiviral Effect." Frontiers in Immunology 12 (August 2, 2021). http://dx.doi.org/10.3389/fimmu.2021.698697.

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Nuclear DNA-binding TCF proteins, which act as the main downstream effectors of Wnt signaling, are essential for the regulation of cell fate and innate immunity. However, their role during viral infection in shrimp remains unknown. Herein, we demonstrated that Litopenaeus vannamei TCF (LvTcf) acts independently of Lvβ-catenin to promote interferon-like protein LvVago1 production, thus mounting the response to WSSV infection. Further, we observed that WSV083, a WSSV serine/threonine protein kinase, bound to LvTcf and phosphorylated it. Phosphorylated LvTcf was then recognized and degraded via the ubiquitin-proteasome pathway. Moreover, mass spectrometry analyses indicated that the T39 and T104 residues of LvTcf were target sites phosphorylated by WSV083. Point mutation analyses suggested that additional sites of LvTcf may undergo phosphorylation via WSV083. Taken together, the current work provides valuable insights into host immunity and viral pathogenesis. LvTcf is not only a modulator of shrimp innate immunity but is also an important target for WSSV immune evasion. Thus, the current findings will help improve disease control in shrimps.
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26

Park, Sung-Ji, Chinami Miyazaki, Charles J. Bruce, Diego Bellavia, Fletcher A. Miller, Steve Ommen, and Jae K. Oh. "Abstract 2488: Correlation Between The Severity Of Diastolic Dysfunction And Cardiac Torsion." Circulation 116, suppl_16 (October 16, 2007). http://dx.doi.org/10.1161/circ.116.suppl_16.ii_548-b.

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Backgrounds: Left ventricular torsion (LVtor) is an integral part of systole and untwisting plays an important role in diastole. The aim of this study was to characterize LVtor and untwisting in different grades of diastolic dysfunction. Methods: We studied 135 patients with normal LV EF with various grades of diastolic dysfunction (40 group1:mild,42 group 2:moderate,and 22 group 3:severe dysfunction) and 31 controls with normal diastolic function. Apical and basal short axis rotations were measured by 2D STE. LVtor was defined as net difference between apical and basal rotation. Results: Age, gender, and EF were similar in 3 groups and control. Mitral annulus early diastolic velocity was reduced in all 3 groups (see table ). Peak LVtor was significantly greater in group 1 compared with control, group 2 and group 3. The time from peak LVtor to Mitral valve opening, and to peak early diastolic velocity were significantly delayed in group 1 compared to control (p=0.0030 and 0.0409, respectively). The twisting rate and untwisting rate were found to be highest in group 1. Conclusions: Systolic torsion and diastolic untwisting are significantly increased in patients with mild diastolic dysfunction. In patients with advanced diastolic dysfunction with increased filling pressure, torsion and untwisting are normalized. Hence, vigorous LV torsion appears to be a compensatory mechanism during an early stage of diastolic dysfunction to maintain normal filling in the setting of reduced longitudinal myocardial motion.
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27

"Limit Value Task Scheduling (LVTS): an Efficient Task Scheduling Algorithm for Distributed Computing Environment." International Journal of Recent Technology and Engineering 8, no. 4 (November 30, 2019): 10457–62. http://dx.doi.org/10.35940/ijrte.d9228.118419.

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The grid computational environment suits to meet the computational demands of large, diverse groups of tasks. Assigning tasks to heterogeneous wide spread resources seems complex and is termed as an NP-Complete problem. A new task scheduling algorithm, called Limit Value Task Scheduling Algorithm (LVTS) is presented to efficiently identify the appropriate resources, which is responsible for the scheduling process. The proposed algorithm (LVTS) schedules the tasks to the appropriate resources by calculating the limit value of the tasks and the ceil value of the tasks which represents the completion time of the last tasks scheduled in the resource with highest processing capacity. The efficiency of the (LVTS) measured based on makespan and resource utilization. Experimental results indicates LVTS algorithm sounds good than the Min-min on both makespan and resource utilization.
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Vitarelli, Antonio, Mauro Bernardi, Giuseppe Placanica, Ysabel Conde, Simona D’Orazio, Simona Stellato, Daniela Battaglia, et al. "Abstract 4243: Assessment Of Physiologic And Pathologic Cardiac Hypertrophy By Two-dimensional Strain And Torsion Analysis." Circulation 118, suppl_18 (October 28, 2008). http://dx.doi.org/10.1161/circ.118.suppl_18.s_852-a.

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PURPOSE . We sought to determine whether speckle tracking imaging (STI) could distinguish between subjects with athletic LVH and those with pathological LVH, such as occurs in hypertensive heart disease, hypertrophic cardiomyopathy (HCM), or aortic stenosis. METHODS . A total of 127 participants were studied, comprising competitive athletes (30), hypertensive heart disease (30), HCM (12), aortic stenosis (25), and healthy volunteers (30). Left ventricular mass index, ejection fraction, diastolic wall thickness, wall thickness ratio and diastolic and systolic wall-to-volume ratios were determined. LV longitudinal peak systolic strain (L-ϵ), peak systolic strain rate (SR-S), peak early diastolic strain rate (SR-E), and peak late diastolic strain rate (SR-A) values were measured by STI in the basal, mid and apical segments in apical 4-chamber view. LV radial strain (R-ϵ) in parasternal short-axis view was determined by STI. Averaged LV rotation and rotational velocities from the base and apex were also obtained (EchoPac, General Electric), and used for calculation of LV torsion (LVtor). RESULTS . Left ventricular (LV) mass indices were similar for all forms of LVH (p>.05), which were higher than those obtained in healthy volunteers (p<.05). Athletes had no significant differences in L-ϵ, SR-E and R-ϵ compared with control subjects (p = .21, .85, and .67, respectively). Patients with pathologic LVH had significantly decreased L-ϵ, SR-E, and R-ϵ (average septum: −15.9 ± 3.4%, 1.71 ± 0.35 s −1 , and 24.5 ± 11.6%, respectively) compared with control subjects (−22.4 ± 3.3%, 2.51 ± 0.49 s −1 , and 37.6 ± 15.2%, respectively; all p<.0005). LVtor increased significantly in pathologic LVH and in athletes compared to normals (p<.005 and .0001, respectively). In pathologic LVH LVtor increased mainly as a result of reduced basal rotation (−3.6±1.2 vs −6.4±1.5 degrees, p=.03). In athletes the LVtor increase was the result of an increase in both basal and apical rotation (basal rotation, −6.2±1.4 vs −9.1±1.6 degrees, p=.05; apical rotation, 16.9±3.1 vs 26.5±4.2 degrees, p=.08). CONCLUSIONS . Pathologic LVH has significant strain and SR-E reduction versus controls and a different pattern of LV torsion compared to athletes.
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29

P, Praveena, Chandrika V S, Baranilingesan I, Ravindran S, and Pazhanimuthu C. "Demand Side Management for Charging Plug-In Hybrid Electric Vehicles." Innovations in Information and Communication Technology Series, December 30, 2020, 152–57. http://dx.doi.org/10.46532/978-81-950008-1-4_032.

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In future the usage of Plug-in hybrid electric vehicles (PHEV) will be in wide range, which will impose huge burden to the distributive system. The peak load at the distribution system can be controlled by Demand Side Management (DSM) strategy. In the proposed study, the load curve of Low-voltage Transformers (LVTs) is made to be flatten, on satisfying the requirement of charging PHEV at given time to the required level. The proposed problem statement is formulated as convex optimization problem, and then the random arrival of PHEV is handled by introducing the moving horizon strategy. Based on this, the PHEV are being disconnected from the LVTs beyond their respective exit times. Such that the demand curve of the LVTs is flattened. This problem is solved using MATLAB and the power demand curves of the LVTs, power curves of the PHEVs and non- PHEV load are compared over a time of 24 hours to show that the power curve is flattened with the penetration of PHEV.
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30

P, Praveena, Chandrika V S, Baranilingesan I, Ravindran S, and Pazhanimuthu C. "Demand Side Management for Charging Plug-In Hybrid Electric Vehicles." Innovations in Information and Communication Technology Series, December 30, 2020, 152–57. http://dx.doi.org/10.46532/978-81-950008-1-4_032.

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In future the usage of Plug-in hybrid electric vehicles (PHEV) will be in wide range, which will impose huge burden to the distributive system. The peak load at the distribution system can be controlled by Demand Side Management (DSM) strategy. In the proposed study, the load curve of Low-voltage Transformers (LVTs) is made to be flatten, on satisfying the requirement of charging PHEV at given time to the required level. The proposed problem statement is formulated as convex optimization problem, and then the random arrival of PHEV is handled by introducing the moving horizon strategy. Based on this, the PHEV are being disconnected from the LVTs beyond their respective exit times. Such that the demand curve of the LVTs is flattened. This problem is solved using MATLAB and the power demand curves of the LVTs, power curves of the PHEVs and non- PHEV load are compared over a time of 24 hours to show that the power curve is flattened with the penetration of PHEV.
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31

Capotosto, Lidia, Maria Ciardi, Gaetano Tanzilli, Mangieri Enrico, Fabio Miraldi, Claudio Mastroianni, Vincenzo Vullo, and Antonio Vitarelli. "Abstract 323: Three-dimensional Transesophageal Echocardiography and Speckle Tracking Echocardiography in Infective Aortic Endocarditis: Analysis of Parameters Predictors of Outcome." Circulation 142, Suppl_4 (November 17, 2020). http://dx.doi.org/10.1161/circ.142.suppl_4.323.

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Purpose: Due to the high mortality and morbidity of patients with aortic endocarditis, careful monitoring is necessary to recognize an early failure of antibiotic and cardiokinetic therapy and avoid a possible cardiogenic or septic shock. The timing of surgery is crucial for patients in whom medical therapy fails. The aim of our study is to identify potential echocardiographic "markers" of adverse events in patients with aortic regurgitation from infective endocarditis. Methods: Seventeen patients with aortic regurgitation (AR) from infective endocarditis were studied by 3-dimensional transesophageal echocardiography (3D-TEE) and transthoracic speckle tracking echocardiography (STE). Fifteen healthy subjects were selected as controls. Vegetation size was assessed by 3D-TEE. Standard transthoracic echocardiographic parameters were determined. Global left ventricular (LV) longitudinal strain (LS), radial and circumferential strain were measured by STE. Averaged LV rotation and rotational velocities from the base and apex were obtained and used for calculation of LV torsion (LVtor). Results: Severe AR had decreased LS compared with control subjects. LVtor decreased significantly in severe AR compared to normals (p<.005) as a result of a predominant decrease in apical rotation. By multivariate analysis, LV-LS (p=0.005), LV-tor (p=0.006) and vegetation size (p=0.009) were predictive of adverse events. ROC curves suggested that thresholds offering an adequate compromise between sensitivity and specificity for adverse events detection were -18.2% for mean global LV-LS (AUC .79), 13mm for vegetation size (AUC .86), and 19.4degrees for LVtor (AUC .81). The combination of vegetation size and LV strain had the highest diagnostic accuracy for identifying adverse outcome, superior to vegetation size (p=.006) or LV strain alone (p=.002). Conclusions: The combined assessment of the characteristics of vegetating masses and LV function strain parameters improves the sensitivity of the echocardiographic indices in predicting cardiac morbidity and mortality of aortic regurgitation from infective endocarditis.
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Ding, Qian, Amber W. Trickey, Seshadri Mudumbai, Robin N. Kamal, Erika D. Sears, and Alex H. S. Harris. "Prevalence and Factors Associated With Low-Value Preoperative Testing for Patients Undergoing Carpal Tunnel Release at an Academic Medical Center." HAND, February 26, 2020, 155894472090649. http://dx.doi.org/10.1177/1558944720906498.

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Background: Routine preoperative screening tests before low-risk surgery cannot be justified if the risks to patients are not outweighed by benefits. Several studies and professional guidelines suggest avoiding screening tests prior to minor operations. We aimed to assess the prevalence and patient characteristics associated with low-value preoperative tests (LVTs) prior to carpal tunnel release (CTR) at an academic medical center. Methods: From electronic medical records, we identified patients aged ≥18 who underwent CTR from 2015 to 2017. We determined the occurrence of 9 common LVTs, such as complete blood count (CBC), basic metabolic profile (BMP), and electrocardiogram (ECG), in the 30 days prior to CTR. Multivariable logistic and Poisson regression were used to identify factors associated with receiving any LVT and the number of LVTs, respectively. Results: Among 572 patients, 248 (43.4%) had at least 1 LVT. The most common tests were ECG (31.3% of CTRs), CBC (27.3% of CTRs), and BMP (23.6% of CTRs). Patient factors associated with higher odds of receiving LVT included older age, higher Elixhauser comorbidity score, and general or regional anesthesia (vs monitored anesthesia care). Conclusions: Low-value preoperative tests were frequently received by patients undergoing CTR and were associated with anesthesia type, age, and number of comorbidities. Although our study focused on CTR, these results likely have implications for other commonly performed low-risk procedures. These findings can help guide efforts to improve the quality and value of surgery for carpal tunnel syndrome and facilitate the development of strategies to reduce LVT, such as audit feedback and provider education.
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33

Zhao, Wei, Peng Li, Geu-Ru Hong, Shizhen Liu, Helene Houle, Gianni Pedrizzetti, Goivanni Tonti, Jagat Narula, and Mani A. Vannan. "Abstract 2487: Torsional and Reverse Rotational Mechanics of the Left Ventricular Apex Is Abnormal in Patients with Type 2 Diabetes Mellitus Independent of Presence of Hypertension, Left Ventricular Hypertrophy, Elevated Filling Pressures and Left Atrial Volume." Circulation 116, suppl_16 (October 16, 2007). http://dx.doi.org/10.1161/circ.116.suppl_16.ii_548-a.

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Background : Diastolic dysfunction (DD) is common in patients with Type 2 DM even in the absence of HTN and LVH. We tested whether apical rotational mechanics offered any additional insights into DD in DM over conventional echo-Doppler measures. Methods: We studied 4 groups : 12 normals (wall thickness-WT 0.9±0.1cm); 17 patients with DM (WT 1.0±0.1cm, HbA1c 7±1%, BP 128±4/68±5 mmHg); 16 patients with DM +HTN (WT 0.9±0.1cm, HbA1c 7±1%, BP 134±23/72±18 mmHg); and 20 patients with DM+HTN+LVH (WT 1.4±0.2cm, HbA1c 7±4%, BP 135±13/76±9mmHg). All patients had normal LVEF and mitral E/A ratio. SAX of the LV apex and base were obtained. Velocity Vector Imaging (Siemens, CA) was used to measure: Longitudinal myocardial velocity (LMV, cm/sec) and strain (LS,%); Apical rotation velocity (ARV, cm/sec)and reverse rotation velocity(ARRV, cm/sec); Apical rotation (AR, degree) and LV torsion-LVTOR (degree/cm, and Circumferential (CS,%) and Radial strains (RS,%). Results: Figure shows LVTOR and % reduction in ARRV data. All other data will be presented. Thus, LV torsion is increased in DM alone or DM+HTN (-LVH) groups. But ARRV is reduced by ~ 20% in these groups even with relatively normal E/E’ ratio and LAVI. In the DM+HTN+LVH group, E/E’ and LAVI are increased and apical rotational mechanics resemble the same spectrum as the above groups but are more severe (~25% reduction in ARRV). Thus, reduction in ARRV is a marker of early DD in DM even in the absence of LVH . Conclusions: Apical rotational mechanics is more sensitive than conventional echo-Doppler measures to identify myocardial DD in type 2 DM even in the presence of normal E/A ratio, LAVI and LVEF, and in the absence of HTN and/or LVH.
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34

Arjania, Neville, and Ronald Heijmans. "Is There Anybody Out There? Detecting Operational Outages from LVTS Transaction Data." SSRN Electronic Journal, 2020. http://dx.doi.org/10.2139/ssrn.3581603.

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35

Prata, Martins. "Why the incidence in dialysis in the Lisbon and Tagus Valley Region (LVTR) is two to three times higher than in other regions of the country." Portuguese Journal of Nephrology & Hypertension 35, no. 2 (July 12, 2021). http://dx.doi.org/10.32932/pjnh.2021.07.124.

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The analysis of data from the Ministry of Health’s Integrated Chronic Kidney Disease Management Platform (PI -GID), reveals the existence of a striking regional difference in the incidence in dialysis. This difference is characterized by high levels of incidence in all regions, except the Alentejo, and extremely high levels in the Lisbon and Tagus Valley region. In this region, the incidence values are two to three times higher than in the others. The difference between regions is the result of a different number of patients starting hemodialysis, since the incidence in peritoneal dialysis is low and similar in all of them. It is difficult to find justification for such a discrepancy since the prevalence of factors usually responsible for the higher or lower level of incidence in dialysis does not differ significantly between them. A probable explanation may lie in the difference found in the concentration of public hemodialysis centers, a fact that may determine a difference in the criteria used for the entry of patients undergoing substitutive treatment of renal function. In fact, we found a close correlation between the number of public hemodialysis centers per million inhabitants and the level of incidence in dialysis. A more comprehensive analysis of the data from the Ministry of Health’s Integrated Chronic Kidney Disease Management Platform (PI -GID), if allowed, would be of enormous interest, not only to explain this discrepancy in the incidence of dialysis between regions, but because it could probably allow an explanation for Portugal having (one of) the highest levels of dialysis incidence in Europe
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