Journal articles: 'Lymph Node Tuberculosis'

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Dembla, Sagar, Shujaath Asif, Aniruddha P. Singh, Anuradha Sekaran, Sundeep Lakhtakia, and D. N. Reddy. "A Giant Lymph Node—Liver Imposter." Journal of Digestive Endoscopy 12, no. 02 (June 2021): 112–13. http://dx.doi.org/10.1055/s-0041-1731585.

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AbstractAbdominal tuberculosis has insidious course and is a diagnostic challenge. Tubercular lymphadenitis is associated with constitutional symptoms and multiple enlarged lymph nodes. Isolated giant lymph nodes are rare in tuberculosis and are common in lymphoma or malignancy. Peripancreatic mass on endosonography are commonly lymph node less than 4 cm. Isolated giant nonnecrotizing lymph node can mimic liver architecture on endoscopic ultrasound but lack a biliary connection.

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Bhavyasri, Mothiki, Chenimilla Nagender Prasad, and Ramulu Madire. "Assessment of peripheral lymph node tuberculosis: a prospective study of 24 cases." Perspectives in Medical Research 11, no. 2 (August 30, 2023): 67–70. http://dx.doi.org/10.47799/pimr.1102.13.

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Abstract Introduction: Tubercular lymphadenitis which comes under Extra-pulmonary Tuberculosis (EPTB) has been affecting mankind since ancient times. Peripheral lymph node involvement is the commonest form of EPTB among which cervical lymph nodes are most frequently affected. Objectives: The aim of this study was to evaluate the demographic, clinical characteristics and treatment outcomes of peripheral lymph node Tuberculosis cases in a rural tertiary health care centre. Methods: The study was conducted prospectively at Prathima Institute of Medical Sciences, Nagunur, Karimnagar between January 2021 to August 2022. Pathologically confirmed cases of lymph node Tuberculosis were assessed and followed up. Results: 24 cases of lymph node TB were included with 83.3% females and 16.6% males (p=0.02) with a mean age of 32.6 ± 15.24 years. The mean age among males was 37 ± 15.59 years and among females was 31.75 ± 15.24 years. 58.3% were from rural areas. All of them presented with a history of swelling, 37.5% had a fever, 50% had a loss of appetite and 54.1% had a loss of weight. 8% had a past history of tuberculosis. 79.1% had cervical swelling and 20.8% had axillary swelling. 83.3% had multiple lymph nodes and 33.3% had lymph node matting. Three cases were lost to follow-up, 79% improved with standard anti-Tuberculosis treatment (ATT) and one case died during treatment. Conclusion: Lymph node TB is still prevalent in TB endemic countries and has to be considered first in the differential diagnosis of peripheral lymph node swellings.

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Vrinceanu, Daniela, Mihai Dumitru, Maria Sajin, Carmen Maria Salavastru, and Adrian Costache. "Lymph node tuberculosis – The ENT surgeon approach in four cases." Romanian Journal of Rhinology 8, no. 32 (October 1, 2018): 241–45. http://dx.doi.org/10.2478/rjr-2018-0028.

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Abstract BACKGROUND. Lymph node tuberculosis is a pathology with an increasing incidence and prevalence in middle income countries. MATERIAL AND METHODS. We present a series of 4 cases with cervical lymph node tuberculosis. We review current principles of diagnosis and treatment from the perspective of the ENT surgeon in a tertiary university clinic. RESULTS. In each case we underline diagnosis difficulties and treatment options. These cases presented management difficulties due to associated morbidities. All cases underwent surgical excision of the afflicted lymph nodes with subsequent microscopic confirmation of tuberculosis. We illustrate key concepts leading to the microscopy diagnosis of lymph node tuberculosis. CONCLUSION. There are various surgical incidents and accidents that the young surgeon must be aware of when approaching neck tuberculous lymph nodes. Further referral of the patient for long-term tuberculosis treatment is mandatory. All patients were supervised for a minimum of 1 year after the initial diagnosis and treatment with no sign of recurrence. A close cooperation between the ENT surgeon, the infectious disease specialist and the pathologist is the key to an optimum approach to lymph node tuberculosis at the head and neck level.

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Bromberg, Silvio Eduardo, and Paulo Gustavo Tenório do Amaral. "Tuberculosis axillary lymph node coexistent breast cancer in adjuvant treatment: case report." Einstein (São Paulo) 13, no. 3 (May 19, 2015): 423–25. http://dx.doi.org/10.1590/s1679-45082015rc2963.

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Coexistence of breast cancer and tuberculosis is rare. In most cases, involvement by tuberculosis occurs in axillary lymph nodes. We report a case of a 43-years-old patient who had undergone adenomastectomy and left sentinel lymph node biopsy due to a triple negative ductal carcinoma. At the end of adjuvant treatment, the patient had an atypical lymph node in the left axilla. Lymph node was excised, and after laboratory analysis, the diagnosis was ganglion tuberculosis. The patient underwent treatment for primary tuberculosis. The development of these two pathologies can lead to problems in diagnosis and treatment. An accurate diagnosis is important to avoid unnecessary surgical procedures.

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Gao, Xiang, Tang-Shun Wang, Juan Cheng, Xiao-Guang Shi, Ke-Xin Zhou, Ming Xin, Zhi-Guo Ding, and Xiao-Heng Chen. "Multiple surgical radical treatment in axillary lymph nodes: A case report." European Journal of Inflammation 17 (January 2019): 205873921983895. http://dx.doi.org/10.1177/2058739219838951.

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Lymph node tuberculosis is a common clinical bacterial infectious disease. Regional lymph node tuberculosis is often difficult to cure by surgically radical resection. In addition, its recurrence rate is higher, and it can easily cause lymphatic leakage. This case was considered to have left axillary lymph node tuberculosis. A combination of clinical examination, ultrasound, and magnetic resonance imaging examinations were performed before surgery. The surgical procedure performed was left axillary lymph node excision. Postoperative pathology confirmed the lymph node tuberculosis. The patient was given anti-tuberculosis drug treatment with no recurrence after 6 months follow-up. This provides new ideas and methods for the clinical treatment of regional lymph node tuberculosis.

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Bajpai, Jyoti, Surya Kant, Ajay Kumar Verma, Darshan Kumar Bajaj, and Akshyaya Pradhan. "Primary tubercular submandibular abscess: a rare presentation in two years old girl." International Journal of Advances in Medicine 5, no. 2 (March 21, 2018): 457. http://dx.doi.org/10.18203/2349-3933.ijam20181090.

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Extra pulmonary tuberculosis (TB) continues to be a serious problem in developing countries. The prevalence of extra pulmonary tuberculosis (EPTB) is higher in immunocompromised, especially human immunodeficiency virus (HIV) co-infected patients. The most common site of extra pulmonary tuberculosis is lymph node followed by pleura. Lymph nodes are pivotal component of immune system and hence they are affected in various conditions like infections, autoimmune disorder, malignancy However, tubercular affliction of submandibular lymph node is not common. Only a few cases of tubercular submandibular abscess in immune-competent children have been reported in literature. Here we report a case of two-year old girl with non-healing multiple submandibular lymph node abscess presenting as a primary tuberculosis that proved diagnostically challenging. She responded favourably to a five drug anti-tubercular regimen.

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Davidson, Nancy Glory, and Navaneethakrishnan Muthulakshmi. "LYMPH NODE TUBERCULOSIS- CURRENT SCENARIO." Journal of Evidence Based Medicine and Healthcare 5, no. 18 (April 30, 2018): 1486–90. http://dx.doi.org/10.18410/jebmh/2018/311.

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Sellar, R. S., E. L. Corbett, S. D'Sa, D. C. Linch, and K. M. Ardeshna. "Treatment for lymph node tuberculosis." BMJ 340, mar10 3 (March 10, 2010): c63. http://dx.doi.org/10.1136/bmj.c63.

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Victor, Coelho, Albert A. Kota, Lalchandami Colney, Beulah Roopavathana, Suchita Chase, and Sukria Nayak. "An audit to study the diagnostic yield of lymph node biopsies under local anaesthesia." International Surgery Journal 7, no. 6 (May 26, 2020): 1804. http://dx.doi.org/10.18203/2349-2902.isj20202385.

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Background: Surgical referrals for lymph node biopsies are common, majority for diagnostic purposes. The indications and the diagnostic yield vary for different sites. We conducted an audit of the lymph node biopsies done over a period of seven months.Methods: The audit included 547 patients who underwent lymph node biopsies under local anesthesia in the department of general surgery over a seven-month period. Parameters such as overall diagnostic yield of lymph node biopsies, disease specific yield of lymph node biopsies with a primary focus on tuberculosis; site specific yield of lymph node biopsies and referral pattern for the request for lymph node biopsies were analysed.Results: 324 samples (59.2%) yielded a definite diagnosis, which included haematological malignancy 102 (31.5%), infectious diseases 131 (40.5%), and 59 (18.5%) malignancy. The diagnostic yield of supraclavicular lymph nodes was found to be highest (72.45%) and the axillary group the lowest (39.8%). The referral pattern seen was 314 (57.4%) from General medicine, 149 (27.2%) from General Surgery, and 84 (15.4%) from Haematology. 130 (23.8%) samples were tested for tuberculosis; the highest yield, acquired from the cervical group (52.8%), lowest from the inguinal region (4%).Conclusions: Our audit revealed significant diagnostic yield of lymph node biopsies from the supraclavicular region. Majority of them were of infectious aetiology and referred from General Medicine. This study supports the introduction of co-ordinated problem-based referral and management pathways for the management of patients with enlarged superficial lymph nodes, supported by regular audits of practice.

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Araújo, Alexandra Novais, Tânia Matos, João Boavida, and Maria João Guerreiro Martins Bugalho. "Thyroid tuberculosis: an unexpected diagnosis." BMJ Case Reports 14, no. 2 (February 2021): e238795. http://dx.doi.org/10.1136/bcr-2020-238795.

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Mycobacterium tuberculosis (MTB) is an aerobic bacillus responsible for tuberculous infection. The the thyroid gland being affected by MTB is a rare condition. A 71-year-old woman had 6 months of slight cervical discomfort. Her neck ultrasound showed, at the right lobe of the thyroid, a dominant heterogeneous nodule of 18 mm and homolateral lymph nodes with suspicious ultrasonographic features. The patient underwent fine-needle aspiration, the results of which were non-diagnostic (thyroid nodule) and reactive pattern (lymph node). A total thyroidectomy was performed and a lymph node was sampled for extemporaneous examination. Surprisingly, necrotising granulomas were documented. The diagnosis was definitely established by a positive culture of the lymph node tissue and molecular detection of MTB. Pulmonary involvement was excluded and she was started on antituberculous agents. In the absence of systemic, specific complaints or history of exposition, histopathology and culture of MTB remain a key step for the diagnosis.

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Eke, Barnabas, Babarinde Ojo, Rymond Vhriterhire, Issac Akper, Victor Ugwu, and Confort Udu. "Surgical peripheral lymph node biopsies in Makurdi, Nigeria." International Journal of Medical and Surgical Sciences 6, no. 3 (November 14, 2019): 75–78. http://dx.doi.org/10.32457/ijmss.2019.024.

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This study aims at determining the diagnostic value of peripheral lymph node biopsy and common causes of lymph node enlargement from biopsies obtained from patients with lymph-node enlargement at different sites in a teaching hospital in north central Nigeria town of Makurdi, Benue State. This is a retrospective study of surgical peripheral lymph node biopsies received in the department of Anatomic Pathology, Benue State University Teaching Hospital, Makurdi, Nigeria from February, 2012 to September, 2019. Total number of lymph node biopsies during the period was 47 representing 1.0% of surgical pathology specimens submitted to the department; 25 cases were females and 22 were males. Metastatic nodal involvement (57%), lymphoma (23%) and tuberculosis lymphadenitis (11%) were the most common causes of lymph node enlargement. All the studied nodes were localized. The most common sites of lymphadenopathy were axillary (21%), cervical (16%) and Inguinal (6%). While axillary lymph node enlargements were mostly associated with tumor metastasis, cervical and inguinal node enlargements were mostly associated with tuberculosis and lymphoma, respectively. Surgical excision of nodal enlargement for histological examination represents a simple, good diagnostic yield with lack of significant morbidity or mortality.

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Kusunoki, Takeshi, Hirotomo Homma, Yoshinobu Kidokoro, Akihisa Yoshikawa, Kumiko Tanaka, Satoko Kubo, Ryo Wada, and Katsuhisa Ikeda. "A Case of Nasopharyngeal Tuberculosis with Cervical Lymph Node Tuberculosis Suspected of Cervical Malignant Disease at the First Examination." Clinics and Practice 11, no. 1 (January 29, 2021): 43–46. http://dx.doi.org/10.3390/clinpract11010008.

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A case of nasopharyngeal tuberculosis with cervical lymph node tuberculosis is reported. The patient was a 20-year-old female immigrant from Vietnam and cook apprentice. Her chief complaint was left neck swelling with pain for three months. She was diagnosed with left neck lymphadenitis at a previous hospital, which suspected malignant lymphoma and referred her to our hospital. At the time of the first visit, she had left lymph swelling with tenderness and granuloma-like masses in the nasopharynx. PET-CT showed accumulations in both the swollen left neck lymph and nasopharynx. The diagnosis of this case would appear to be nasopharyngeal cancer with left and neck lymph node metastasis or nasopharyngeal tuberculosis with cervical lymph node tuberculosis in addition to malignant lymphoma. Based on some examinations (biopsy, bacteria culture, and imaging), it was diagnosed as nasopharyngeal tuberculosis with cervical lymph node tuberculosis. Therefore, she was treated with anti-tuberculosis agent in respiratory medicine.

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Djossou, H. Julien, Mohamed Ahmed Ghassem, Hamza Toufik, Mohamed Oukabli, Ahmed Bezza, and Lahsen Achemlal. "Hodgkin Lymphoma Mimicking Lumbar Spine Tuberculosis." Case Reports in Rheumatology 2022 (February 25, 2022): 1–4. http://dx.doi.org/10.1155/2022/5298960.

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Introduction. The clinical manifestations of Hodgkin lymphoma (HL) can closely mimic spine and lymph node tuberculosis (TB). Case Description. A 48-year-old man was initially treated for retroperitoneal lymph nodes TB, and this diagnosis was made without bacteriological and histopathological confirmation. After four months of regular therapy for TB, he did not improve and was admitted to our department for lumbar spine pain. We first made diagnosis of tuberculous spondylodiscitis, and anti-TB treatment was strengthened. But, after three weeks of hospitalization, his condition worsened clinically with onset of swelling of the left supraclavicular lymph node. So, after surgical excision and anatomopathological examination of the lymph node, the diagnosis of nodular sclerosis classic Hodgkin lymphoma was made. He was treated by chemotherapy, and his condition improved significantly after the first 2 cycles of chemotherapy. Conclusion. Repeated investigations may be helpful in establishing a correct diagnosis and starting an effective treatment in this highly curable disease.

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Soualili, Nadim Abdelhak, Meriem El Batoul Bourouba, Yacine Nacereddine, Sihem Boussafsaf, Nabila Talbi, Ibtissem Selmani, Oualid Nebbar, Messaoud Zarat, and Naouel Lemdaoui. "Breast Carcinoma and Tuberculosis in Axillary Lymph Nodes: A Case Report." EAS Journal of Medicine and Surgery 5, no. 07 (August 6, 2023): 111–13. http://dx.doi.org/10.36349/easjms.2023.v05i07.002.

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The coexistence of tuberculosis with axillary lymph node metastases in breast carcinoma is rare. Axillary lymph node metastasis is the most important factor in the staging of breast carcinoma, this can mimic or complicate the staging of a malignant disease. Dual organ pathology can lead to interpretation difficulties and inappropriate treatment of tuberculosis as well as breast carcinoma. We report an observation of infiltrating carcinoma of the non-specific type of the breast in woman aged 39, where tuberculosis was found in the axillary lymph nodes in addition to metastases. The possible and simultaneous occurrence of breast carcinoma and tuberculosis should be mentioned in order to avoid difficulties of interpretation and allow adequate management of axillary tuberculous lymphadenitis and breast carcinoma.

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Ganchua, Sharie Keanne C., Anthony M. Cadena, and JoAnne L. Flynn. "Estimating total numbers of Mycobacterium tuberculosis in lymph nodes of cynomolgus and rhesus macaques." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 65.12. http://dx.doi.org/10.4049/jimmunol.196.supp.65.12.

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Abstract Tuberculosis (TB) is predominantly thought of as a lung disease. However, in classic pathology studies, a thoracic lymph node is often infected in addition to the lungs. Furthermore, lymphadenitis is common in children infected with Mycobacterium tuberculosis (Mtb). In our non-human primate model, at least one lymph node is infected in nearly all macaques. However, rhesus macaques have substantially more lymph node involvement than cynomolgus macaques, and this often leads to clinical deterioration. To better understand the role of lymph nodes in TB, as well as the differences between these species, we quantified the total number of Mtb genomes (live and dead bacteria) in the lymph nodes at 4 and 12 weeks post-infection (p.i.). Mtb burden in the lymph nodes was not significantly different between cynomolgus and rhesus macaques, as well as between 4wk and 12wk p.i.. We then compared the number of Mtb genomes with the number of viable bacteria to determine the degree of bacterial killing in these tissues. Overall, bacterial killing in lymph nodes was very low, compared to lung granulomas. However, the 12wk p.i. rhesus macaques had significantly less Mtb killing in their lymph nodes than the 4wk p.i. rhesus and 12wk p.i. cynomolgus macaques, which could in part explain the greater lymph node involvement in rhesus macaques. The level of bacterial killing between intact and effaced (necrotic) lymph nodes was similar; however, there was a trend of increasing Mtb burden as the effacement increases. Some lymph nodes without culturable bacteria were found to have Mtb genomes present, suggesting lymphatic spread. Our preliminary data suggest that lymph nodes may play a role as a bacterial reservoir and as a means of bacterial dissemination and reactivation.

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Falcón, Jesús, and Mercedes Bogado. "Coinfection of lymph node tuberculosis and paracoccidioidomycosis." Revista Virtual de la Sociedad Paraguaya de Medicina Interna 7, no. 1 (March 30, 2020): 129–33. http://dx.doi.org/10.18004/rvspmi/2312-3893/2020.07.01.129-133.

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Mattila, Joshua T., Andrew W. Simonson, Kathryn C. Krupinsky, Denise E. Kirschner, and JoAnne L. Flynn. "Macrophages and neutrophils in lymph node granulomas from Mycobacterium tuberculosis-infected macaques have immunoregulatory phenotypes." Journal of Immunology 210, no. 1_Supplement (May 1, 2023): 71.26. http://dx.doi.org/10.4049/jimmunol.210.supp.71.26.

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Abstract Tuberculosis (TB) is caused by infection with the Mycobacterium tuberculosis (Mtb). Lung granulomas are the defining pathologic feature of TB but Mtb can infect other organs, including lymph nodes, and causes granulomas to form in these sites. Lymph node granulomas have received less attention than lung granulomas but granulomas in these organs are sites of bacterial persistence and have implications for TB progression. Macrophage subsets and neutrophils in lymph node granulomas have not been extensively studied but the biology of these cells may yield clues that underlie the pathobiology of lymph node infection. Our objective was to describe expression of functional markers and cytokine expression by macrophage subsets and neutrophils in lymph node granulomas and to compare these myeloid cells in lymph node and lung granulomas. We used thoracic lymph node and lung granulomas from cynomolgus macaques, a nonhuman primate that experiences human-like TB pathology and course of disease, to do this work. We found that lymph node epithelioid macrophages were distinct from lymph node dendritic cells but resembled epithelioid macrophages in lung granulomas suggesting these cells share a common progenitor or exposure to common stimuli leads to a phenotypic convergence in different tissues. Macrophages expressed pro- and anti-inflammatory cytokines including type 1 interferon, a cytokine family associated with exacerbated TB. Neutrophils were present in low numbers in non-granulomatous lymph node regions but were selectively recruited to granulomas. Our data suggest that macrophages and neutrophils in lymph node granulomas have immunoregulatory properties that may contribute to local and systemic outcomes in Mtb infection. This work is supported by NIH grants R21 AI167710, R01AI164970, and the Wellcome Trust DELTA tissue program.

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Papkov, Aleksandr V., Dmitriy B. Giller, and Vitaliy L. Dobin. "Effectiveness of mediastinal lymphadenectomy in surgical treatment of generalized destructive pulmonary tuberculosis." I.P. Pavlov Russian Medical Biological Herald 26, no. 4 (December 29, 2018): 511–18. http://dx.doi.org/10.23888/pavlovj2018264511-518.

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Bronchopleural complications after pneumonectomy in generalized destructive tuberculosis are associated with the presence of intrathoracic lymph nodes (ITLN) with caseous alterations. Aim. To improve the effectiveness of surgical treatment of patients with generalized destructive pulmonary tuberculosis by development and introduction of the method of mediastinal lymphadenectomy in tuberculous lesion of mediastinal lymph nodes. Materials and Methods. Results of surgical treatment of 515 patients with generalized destructive pulmonary tuberculosis were analyzed. In 274 of them the surgical treatment was supplemented with mediastinal lymphadenectomy (the main group). In the control group (241 patients) only resection was performed without removing lymph nodes. Results. Analysis of the postoperative course of the disease in both groups of patients (with mediastinal lymphadenectomy and without it) showed that bronchopleural complications occurred in 7 (2.6%) cases in the main group and in 30 (12.4%, p<0.05) cases in the control group. In the main group exacerbation of the specific process was noted in 1 patient (0.4%), and in comparison group in 9 patients (3.7%, p<0.05). Elimination of macroscopically altered ITLN in widespread destructive tuberculosis permitted to reduce the complications rate in the postoperative period by 64.8% (p<0.05). Indications to removal of IHLN included: a) enlargement of ITLN (>2 sm) and in duration; b) fusion with the surrounding tissues, softening of the node tissue in its caseous melting, c) existence of yellowish or whiter in comparison with the surrounding tissue inclusions in the node being manifestations of tuberculous granuloma. In histological, cytological and bacteriological examination, these macroscopic signs in 97% of cases indicated active tuberculosis of mediastinal lymph nodes. Conclusions. In 97% of cases, widespread destructive secondary pulmonary tuberculosis runs with an active specific process in mediastinal lymph nodes which makes it reasonable to perform a selective lymphadenectomy in such group of patients. Secondary damage of different groups of intrathoracic lymph nodes by the active process depended on localization of lung destructions and occurred along the routes of lymph drainage from them. Reliable signs of active tuberculous of ITLN include: more than 2.0 cm lymph node enlargement, in duration, periadenitis, fluctuation and in homogeneity. Removal of macroscopically altered intra-thoracic lymph nodes in widespread destructive pulmonary tuberculosis permits to reduce the rate of complications in the postoperative period by 64.8%.

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Sali, Gaurav, Iqbal Ali, Gurmohan Sethi, and Gurjit Singh. "Incidental cystic duct lymph node tuberculosis." International Journal of Case Reports and Images 4, no. 6 (2013): 337. http://dx.doi.org/10.5348/ijcri-2013-06-326-cr-11.

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Kawamoto, Katsuyuki, Hiromi Takeuchi, Kei Nakahara, Shigeru Higami, and Hiroya Kitano. "Evaluation of Cervical Lymph Node Tuberculosis." Practica Oto-Rhino-Laryngologica 96, no. 7 (2003): 647–52. http://dx.doi.org/10.5631/jibirin.96.647.

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KULCHАVENYA, E. V., E. YU KOVESHNIKOVА, M. M. MERGАNOV, and F. R. SHАRIPOV. "PERIPHERAL LYMPH NODE TUBERCULOSIS: EPIDEMIOLOGICAL CHARACTERISTICS." TUBERCULOSIS AND LUNG DISEASES 96, no. 10 (2018): 30–34. http://dx.doi.org/10.21292/2075-1230-2018-96-10-30-34.

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Roubaud-Baudron, Claire, Maxime Godard, Sandrine Greffard, Jacques Boddaert, and Marc Verny. "LYMPH NODE TUBERCULOSIS AND PARADOXICAL EVOLUTION." Journal of the American Geriatrics Society 58, no. 1 (January 2010): 192–93. http://dx.doi.org/10.1111/j.1532-5415.2009.02635.x.

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RUTOWITSCH, M. "Tuberculosis cutis colliquativa in lymph node." Journal of the European Academy of Dermatology and Venereology 11 (September 1998): S241. http://dx.doi.org/10.1016/s0926-9959(98)95480-0.

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Yilmaz, Yusuf Yagmur, Ali Kemal Uzu, Fahri. "Tuberculosis in an Intramammary Lymph Node." European Journal of Surgery 166, no. 3 (May 24, 2000): 267–68. http://dx.doi.org/10.1080/110241500750009401.

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Singh, Gurminder, Neeraj Joshi, Robin Garg, and Sudhanshu Garg. "Mediastinal tuberculosis in adult: case report." International Journal of Research in Medical Sciences 5, no. 5 (April 26, 2017): 2246. http://dx.doi.org/10.18203/2320-6012.ijrms20171879.

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Mediastinal lymph node enlargement commonly seen in sarcoidosis, lung cancer, lymphoma and tuberculosis in children’s. Tuberculosis in adult mostly involve parenchyma of lung and very rarely involve mediastinal lymph nodes, here we report a 27-year-old male, non-diabetic, non-hypertensive, non-alcoholic and non-smoker who present with low grade fever and dry cough. Search for the cause of morbidity revealed him to be suffering from mediastinal tuberculosis. He was treated for tuberculosis with ATT.

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Manjani, Sekar, Jackson Bose, Jamunarani Srirangaramasamy, and Khowsalya Subrajaa Karupasamy. "Kikuchi fujimoto disease in a young male post-COVID -19 vaccination." IP Archives of Cytology and Histopathology Research 8, no. 4 (January 15, 2024): 268–70. http://dx.doi.org/10.18231/j.achr.2023.061.

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Kikuchi disease (Kikuchi-Fujimoto disease) is one of the rarest forms of lymphadenopathy. It is also known as necrotizing lymphadenitis. The patients usually present with fever and lymphadenopathy. Here is a case of Kikuchi-Fujimoto disease presented with fever and cervical lymphadenopathy. Radiological imaging revealed matted lymph nodes. Fine needle aspiration of the lymph node revealed granulomatous inflammation. Acid Fast stain was negative and further investigations ruled out tuberculosis. A histopathological biopsy of the lymph node confirmed the diagnosis of Kikuchi-Fujimoto disease. The patient was treated with medications and the patient's condition improved in follow-up. Tuberculosis must be ruled out in such conditions as the symptoms and radiological and FNAC findings mimicking tuberculosis. The diagnosis of Kikuchi-Fujimoto disease is made by histopathology and confirmed by immunohistochemistry.

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Mandal, Prakas Kumar, Supriyo Sarkar, Malay Kumar Ghosh, and Maitreyee Bhattacharyya. "Simultaneous dual pathology in lymph node." Mediterranean Journal of Hematology and Infectious Diseases 6, no. 1 (May 31, 2014): e2014036. http://dx.doi.org/10.4084/mjhid.2014.036.

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[Abstract]Tubercuous lymphadenitis and Non Hodgkins’ Lymphoma are common in India. As both diseases can occur in elderly persons there is a definite chance of co-existence of both diseases; but that coexistence has not been reported. Here we present a unique case in an elderly woman who had synchronous double pathology of tuberculosis (TB) and Diffuse Large B cell Lymphoma (DLBCL) of the lymph nodes. Key words:- lymph nodes, tuberculosis (TB), Diffuse Large B cell Lymphoma (DLBCL).

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Bibi, Sidra, Kainaat Ali, and Aasiya Niazi. "Histomorphological patterns of lesions in lymph node biopsies." Journal of Rawalpindi Medical College 25, no. 1 (July 15, 2021): 24–29. http://dx.doi.org/10.37939/jrmc.v25i1.1740.

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Introduction: Lymph node biopsies are routinely performed for the evaluation of lymphadenopathies. Tuberculosis and other infections are the major causes of lymphadenopathy in developing countries. The pattern of lymph node enlargement is different for different age groups. Malignancies are common in adults as compared to children.Objective: To document the incidence of diseases causing lymphadenopathy along with the demographics of the population under study, and to correlate site and size of lymphadenopathy with the histopathological diagnosis.Materials and Methods: A total of 163 patients whose lymph nodes biopsies were performed from January 2015 to June 2018 were included in the study. All demographic and laboratory data were recorded on a proforma and analyzed using SPSS version 22.Results: A total of 163 biopsies were studied with ages ranging from 03 to 96 years. Female patients were 57.05% and male patients 42.94%. In the studied cases, 74.84% were found to be non-neoplastic, 13.5% neoplastic while 11.65% of cases biopsies were either unremarkable or non-lymphoid tissue was biopsied. Reactive hyperplasia was the commonest lesion accounting for 50.3% of cases, followed by tuberculosis (23.3%), metastatic carcinoma (6.2%), lymphoproliferative disorders (1.84%), Hodgkin’s lymphoma (3%), non-Hodgkin’s lymphoma (2.45%) and non-caseating granulomatous lymphadenitis (1.22%) respectively. Lymph node size was found to be greater than 2cm in only 25.7% of cases.Conclusion: Reactive hyperplasia and tuberculosis are the most common diagnosis in lymph node biopsies. Lymph node biopsy is a diagnostic and reliable histologic investigation to differentiate non-neoplastic lesions from neoplastic lesions, and further classify the disease based on microscopic findings in both cases.

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Wolf, Andrea J., Ludovic Desvignes, Beth Linas, Niaz Banaiee, Toshiki Tamura, Kiyoshi Takatsu, and Joel D. Ernst. "Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs." Journal of Experimental Medicine 205, no. 1 (December 24, 2007): 105–15. http://dx.doi.org/10.1084/jem.20071367.

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The onset of the adaptive immune response to Mycobacterium tuberculosis is delayed compared with that of other infections or immunization, and allows the bacterial population in the lungs to expand markedly during the preimmune phase of infection. We used adoptive transfer of M. tuberculosis Ag85B-specific CD4+ T cells to determine that the delayed adaptive response is caused by a delay in initial activation of CD4+ T cells, which occurs earliest in the local lung-draining mediastinal lymph node. We also found that initial activation of Ag85B-specific T cells depends on production of antigen by bacteria in the lymph node, despite the presence of 100-fold more bacteria in the lungs. Although dendritic cells have been found to transport M. tuberculosis from the lungs to the local lymph node, airway administration of LPS did not accelerate transport of bacteria to the lymph node and did not accelerate activation of Ag85B-specific T cells. These results indicate that delayed initial activation of CD4+ T cells in tuberculosis is caused by the presence of the bacteria in a compartment that cannot be mobilized from the lungs to the lymph node, where initial T cell activation occurs.

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Belizna, C., J. M. Kerleau, F. Heron, and H. Levesque. "Tonsillar and lymph node tuberculosis revealing asymptomatic pulmonary tuberculosis." QJM 100, no. 12 (November 24, 2007): 800–801. http://dx.doi.org/10.1093/qjmed/hcm090.

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Alaoui, M. Maliki, Y. Ibrahimi, A. Harchouni, R. Mssrouri, J. Mdaghri, A. Taghy, M. K. Lahlou, and A. Settaf. "The Association of Cervical Lymph-Node with Thyroid Papillary Carcinoma, Case Report." Scholars Journal of Medical Case Reports 10, no. 6 (June 6, 2022): 536–38. http://dx.doi.org/10.36347/sjmcr.2022.v10i06.009.

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The association of cervical adenopathie with a cervical carcinoma location suggests a lymph node metastasis and requires a complicated and radical surgery. The most common location of extrapulmonary tuberculosis is cervical lymph nodes (63-77%) [1]. We report a tuberculous lymphadenetis mimicking lymph node metastasis in a 35-year-old patient operated for progressive cervical tumefaction. It was a papillary thyroid carcinoma found after an isthmo-lobectomy. The pathologic findings imposed a thyroidectomy totalization and an ipsilateral central neck lymph node dissection. The operatory finding of a controlateral adenopathy manly with the development of a controlateral cervical adenopathie suggesting lymph node metastatic extension. A lymph node excision was undertaken and the pathologic study revealed a tuberculous lymphadenitis. The patient was treated by put under antibacillary treatment and evolution was satisfactory. We also expose, through this work, a certain number of techniques of exploration likely to ascertain the diagnosis of a tuberculous lymphadenitis and to monitor the therapeutic strategy.

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Meneses Navas, M. K., P. Romero Fernández, M. N. Cabrera Martín, A. Ortega Candil, and J. L. Carreras Delgado. "Nodal tuberculosis on positron emission tomography/computed tomography with 18F-Fluordexosiglucose, a case report." ANALES RANM 138, no. 138(02) (August 31, 2021): 183–85. http://dx.doi.org/10.32440/ar.2021.138.02.cc03.

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Tuberculosis is an infectious disease, caused by the Mycobacterium tuberculosis bacillus. Extrapulmonary disease can cause nonspecific symptoms and signs, which makes diagnostic suspicion difficult. We present the case of a man with a history of cancer in complete remission, diagnosed with lymph node tuberculosis, after being admitted to our hospital due to fever, dyspnea, and central chest pain. A Positron Emission Tomography / Computed Axial Tomography with 18F-fluordexosiglucose is requested; which showed multiple mediastinal adenopathic conglomerates with intense radiotracer uptake, suggesting ruling out malignancy. Active lymph node tuberculosis will show increased metabolic activity with Positron Emission Tomography / Computed Tomography with 18F-fluordexosiglucose, which could make the differential diagnosis with malignant tumors or other granulomatous diseases difficult, as in the case of our patient. Therefore, it is important to consider lymph node tuberculosis as a differential diagnosis in patients with adenopathies suspected of malignancy.

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Rahman, Md Atiqur, Md Mamun Ali Biswas, Syeda Tasfia Siddika, and Abdul Mannan Sikder. "Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study." Journal of Enam Medical College 2, no. 1 (September 24, 2012): 8–14. http://dx.doi.org/10.3329/jemc.v2i1.11915.

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Background: Lymphadenopathy is a common manifestation of a large variety of disorders,both benign and malignant. It is essential to define the pattern of disorders presenting primarily as lymph node enlargement in a particular environment. Histopathological examination of the lymph node biopsies is a gold standard test in the distinction between reactive and malignant lymphoid proliferations as well as for detailed subtyping oflymphomas. We designed this study in our population for histopathological evaluation of lymph nodes that might be helpful for clinical management of these lesions. Objective: Histopathological evaluation of lymphadenopathy from excised specimen, in relation to ageand sex of the patients, and distribution of the lymph nodes. Materials and Methods: It was a retrospective cross sectional study conducted in the department of Pathology, Enam MedicalCollege & Hospital, Savar, Dhaka during the period from January 2006 to December 2010. Lymph node biopsies of all patients of both sexes and all age groups were included.Metastatic lymph nodes associated with evidence of primaries elsewhere in the body were excluded from the study. Total 191 lymph node biopsies were selected for histopathological evaluation. Among these 90 (47.12%) were from males and 101 (52.88%) were from females with male to female ratio being 1:2.1. The age of the patients ranged from 2 to 85 years with a mean age of 35.73 ± 18 years. Results: Cervical lymph nodes were the most common (56%) biopsied group. Of the 191 cases 59 cases (30.89%) were reactive lymphadenitis, 64 cases (33.5%) were tuberculosis, 2 cases (1.05%) were non-caseous granuloma, 11 cases (5.76%) were Hodgkin lymphoma, 22 cases (11.52%) were non-Hodgkin lymphoma, 24 cases (12.57%) were metastatic neoplasm and 9 cases (4.7%) were other lesions.Conclusion: Tuberculosis was the most common cause of lymphadenopathy, followed by reactive lymphadenitis and the cervical group of lymph nodes was most frequently affected. DOI: http://dx.doi.org/10.3329/jemc.v2i1.11915 J Enam Med Col 2012; 2(1):8 -14

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Melo, Valdinaldo Aragão de, Gustavo Barreto de Melo, Renata Lemos Silva, Nestor Piva, and Maria Luiza Dória Almeida. "Tuberculosis of the cystic duct lymph node." Brazilian Journal of Infectious Diseases 8, no. 1 (February 2004): 112–14. http://dx.doi.org/10.1590/s1413-86702004000100009.

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Sasaki, Yuko, Masashi Yamamoto, Tadayuki Yasoshima, and Hideo Edamatsu. "Five Cases of Cervical Lymph Node Tuberculosis." Practica oto-rhino-laryngologica. Suppl. 143 (2015): 65–67. http://dx.doi.org/10.5631/jibirinsuppl.143.65.

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D. MASI, MAJ JOSE, and CYRIL TOKER. "Diffuse Hyperplasia of Lymph Node in Tuberculosis." Southern Medical journal 79, no. 7 (July 1986): 891–93. http://dx.doi.org/10.1097/00007611-198607000-00026.

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Pentti, Mikko. "Cervical Lymph Node Tuberculosis And The Tonsils." Acta Pathologica Microbiologica Scandinavica 26, no. 4 (August 18, 2009): 603–8. http://dx.doi.org/10.1111/j.1699-0463.1949.tb00759.x.

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WISLØFF, F., and H. C. GODAL. "Congenital Spherocytosis unmasked by Lymph Node Tuberculosis." Scandinavian Journal of Haematology 31, S39 (April 24, 2009): 19–21. http://dx.doi.org/10.1111/j.1600-0609.1983.tb02149.x.

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Liu, Jiang, Shouning Xie, Laishun Yu, and Xiaoling Su. "Multidrug resistant lymph node fistula tracheobronchial tuberculosis." Medicine 98, no. 49 (December 2019): e18288. http://dx.doi.org/10.1097/md.0000000000018288.

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Zhang, Lin-Qian, Xiao-Bing Li, and Yun-Guang Bao. "DOCK8 deficiency with mediastinal lymph node tuberculosis." World Journal of Pediatrics 16, no. 2 (April 23, 2019): 213–14. http://dx.doi.org/10.1007/s12519-019-00251-5.

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McCarthy, O. R., and R. M. Rudd. "Six months' chemotherapy for lymph node tuberculosis." Respiratory Medicine 83, no. 5 (January 1989): 425–27. http://dx.doi.org/10.1016/s0954-6111(89)80075-7.

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MJ, Alam, Jonaed FE, Rifat MA, Liton MA, Nahiduzzaman Nahiduzzaman, Reza IMHR, and Mamun SKAA. "Pattern of Lymph Node Involvement and Clinical Presentations of Tuberculous Cervical Lymphadenitis in a Single Center Tertiary Level Hospital." Scholars Journal of Applied Medical Sciences 11, no. 08 (August 18, 2023): 1474–79. http://dx.doi.org/10.36347/sjams.2023.v11i08.016.

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Introduction: Tuberculous cervical lymphadenitis, also known as scrofula, is a common manifestation of extra pulmonary tuberculosis. It primarily affects the lymph nodes in the neck region and is caused by Mycobacterium tuberculosis. TCL presents with distinct clinical features and a characteristic pattern of lymph node involvement. This short overview aims to analyze the pattern of lymph node involvement and clinical presentations of TCL to improve diagnostic accuracy and patient care. Aim of the study: The aimed to analyze the pattern of lymph node involvement and clinical presentations of TCL. Methods: This prospective observational study was conducted at the Dhaka Medical College Hospital, Dhaka, Bangladesh, over a period of four years. A total of 189 TCL patients were included in the study, with data collected on socio-demographic characteristics, clinical presentations, neck swelling-related characteristics, and various laboratory findings. Result: The majority of the participants were between the ages of 15-30 years (71.43%) and were predominantly female (68.25%). Fever was the most common clinical presentation (66.67%), followed by abscess (49.21%) and cough (30.16%). Unilateral neck swelling on the right side was the most prevalent (41.27%). Swollen nodes were frequently observed, primarily at node levels II, III, IV, V, and VI. High ESR (58.73%) and positive CGD on FNAC (100%) were common laboratory findings. Gene-Xpert testing showed positive results in 87.50% of cases. During the follow-up period, fever, neck pain, and neck swelling gradually decreased, while new abscess occurrences decreased over time. Surgery was performed on 4.23% of participants with single-level swollen nodes and 19.10% with multi-level swollen nodes after 1 year. Conclusion: In summary, this study on tuberculous lymphadenitis (TCL) identified consistent patterns in lymph node involvement and clinical presentations. Fever, abscess formation, and cough were common symptoms, .......

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Gubkina, M. F., I. Yu Petrakova, M. A. Bagirov, N. V. Yukhimenko, Yu Yu Khokhlova, and S. S. Sterlikova. "Differentiated Approaches to the Choice of Timing of Surgical Treatment for Intrathoracic Lymph Node Tuberculosis in Children during Increasing Incidence of Multiple Drug Resistant Tuberculosis." Tuberculosis and Lung Diseases 100, no. 7 (August 11, 2022): 14–21. http://dx.doi.org/10.21292/2075-1230-2022-100-7-14-21.

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The objective: to develop differentiated approaches to the choice of timing of surgical treatment of intrathoracic lymph node tuberculosis (ITLNTB) in children during the increasing incidence of multiple drug resistant tuberculosis (MDR-TB).Subjects and Methods. 52 patients of 2-12 years old had their intrathoracic lymph nodes removed at different stages of anti-tuberculosis therapy. All children had massive (more than 10-15 mm) conglomerates in their intrathoracic lymph nodes. Additionally to changes in intrathoracic lymph nodes, 12 people had active tuberculous changes in the lungs or bronchial tuberculosis.Results. 5 patients were operated before chemotherapy, 35 patients after 2 months of treatment, and 12 patients underwent surgery afterwards. The elective surgery was performed in 51 children, and 1 child had surgery before the start of chemotherapy due to vital indications (the threat of breakthrough of caseous masses into the trachea).Planned surgical treatment in children with tuberculosis of intrathoracic lymph nodes should be carried out within the following timing: before the start of anti-tuberculosis therapy in the absence of clinical, laboratory and radiological signs of the disease being active; as soon as possible from the start of chemotherapy (it is enough to focus on the results of the first CT control after 2 months of treatment (there should be no tendency to involution of pathological changes) in the presence of minimal signs of tuberculosis activity). The choice of timing of planned surgical treatment is individual and determined by the timing of stabilization of pulmonary changes or the cure of bronchial tuberculosis (after 6, 9, 12 months) in patients with newly diagnosed active tuberculosis of intrathoracic lymph nodes in combination with lung and/or bronchial lesions. The development of life-threatening complications is an absolute indication for emergency surgery.

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Paul, TK, MN Baqui, and R. Parveen. "Tuberculosis of Cystic Lymph Node of Lund-A Rare Presentation." Journal of Surgical Sciences 17, no. 1 (October 27, 2019): 62–63. http://dx.doi.org/10.3329/jss.v17i1.43714.

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Tuberculosis is one of the major infectious diseases in Bangladesh. After respiratory system, lymphatic and gastrointestinal tracts are the commonest sites of development of this pathology. However, hepatobiliary tuberculosis is rare, seen in approximately 1% of all abdominal cases. Reporting of tuberculosis of the cystic duct lymph node is very uncommon. Its diagnosis is difficult because of the absence of characteristic symptoms and signs. In this case report, we present a case of tuberculosis of cystic duct lymph node. Journal of Surgical Sciences (2013) Vol. 17 (1) : 62-63

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Tanisha, Iryna Melnychuk, and Maryna Sharayeva. "Approach to lymphadenopathy: how to diagnose tuberculosis lymphadenitis." Ukrainian Scientific Medical Youth Journal 142, no. 4 (December 4, 2023): 37–41. http://dx.doi.org/10.32345/usmyj.4(142).2023.37-41.

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lymphadenopathy is considered as abnormal finding local or generalized that can be caused by neoplasm or infection, as tuberculosis lymphadenitis. Cervical localization has prevalence in the variety of disorders, can has a similar kind of clinical presentation and to differentiate them becomes extremely difficult. We provided a case report of the new onset of extrapulmonary tuberculosis lymphadenitis in 42-year-old Indian man. The patient complained of multiply enlarged painful lymph nodes on left anterior neck and was also concerned about sore throat persistent for a year. Objective examination and analysis were without evident inflammatory signs. Previous ultrasound, pulmonary and abdominal CT-scan investigations also revealed conglomerate of left mediastinal lymph nodes, moderate splenomegaly. The preliminary diagnosis of lymphoma was excluded due to confirmation of typical tuberculosis lymphadenitis with specific testing and morphological changes of the resected lymphatic node. Sputum microscopy was found to be negative, which meant that the patient was negative for social transmission of tuberculosis. Affected lymph nodes resolved completely after appropriate therapy during one-year treatment. This case report of extrapulmonary tuberculosis highlights the importance of tissue diagnosis in unclear situations. We used clinical protocol for unspecified lymph node enlargement as complete history taking and physical examination that is preliminary for diagnosis, while laboratory tests, imaging diagnostic methods and tissue samplings are gold standard evaluation for definite lymphadenopathy. Tuberculosis lymphadenitis is popularly known as collar stud abscess and is the most common benign cause of cervical lymphadenopathy in endemic areas. This observation determined the details of the immunocompromised state of the patient, conclusion was supported by the evidence of Pseudomonas putida associated pharyngitis. The main differential signs between lymphoma as immunoproliferative disorder and infectious tuberculosis lymphadenitis were provided.

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Choudhary, Prabesh Kumar, Niraj Nepal, Nirajan Mainali, and Gaurav Chhetri. "Diagnostic Role of Lymphnode Imprint: A Cyto-histopathological Correlation." Nepalese Medical Journal 2, no. 1 (June 20, 2019): 138–40. http://dx.doi.org/10.3126/nmj.v2i1.24053.

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Introduction: Lymphadenopathy is a very common condition for which excision biopsy is often recommended when fine needle aspiration cytology is not conclusive. Lymph node imprint cytology is a useful and rapid alternative diagnostic tool. This study was conducted to assess the accuracy of lymph node imprint cytology as compared to the histopathology.Materials and Methods: Imprint smears were made from all cases of lymphadenopathy. The smears were evaluated by three pathologists and categorized into, inflammatory lesions and primary and metastatic tumors. Imprint smears were made from lymph node excision specimens and were stained with PAP and MGG stains. The diagnosis in imprints was compared with those given by histopathology. With the help of sensitivity, specificity & accuracy, the agreement between the imprint smear and histopathology was determined.Results: Among the total 92 cases, 40 (43.4%) cases were chronic non-specific lymphadenitis, 22 (23.9%) were tuberculosis and metastatic lesions each. The overall accuracy of lymph node imprint cytology was 96.73%, 96.74%, 96.74% and 100% for tuberculosis, chronic non-specific lymphadenitis, lymphoma, and metastatic lesions respectively.Conclusions: Lymph node imprint smears is a rapid diagnostic tool and can be used routinely as an adjunct to histopathology in the diagnosis of various lymph node disorders.

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Eshete, Abdurehman, Ahmed Zeyinudin, Solomon Ali, Solomon Abera, and Mona Mohammed. "M. tuberculosisin Lymph Node Biopsy Paraffin-Embedded Sections." Tuberculosis Research and Treatment 2011 (2011): 1–5. http://dx.doi.org/10.1155/2011/127817.

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Background. Tuberculosis lymphadenitis is one of the most common forms of all extrapulmonary tuberculosis.Objective. To evaluate the magnitude ofM. tuberculosisfrom lymph node biopsy paraffin-embedded sections among suspected patients visiting the Jimma University Specialized Hospital.Method. A cross-sectional study design of histological examination among lymph node biopsy paraffin-embedded sections by Ziehl-Neelsen and hematoxylin/eosin staining technique was conducted from December, 2009, to October, 2010, at the Department of Medical Laboratory Science and Pathology.Result. Histopathological examination of the specimens by hematoxylin and eosin staining technique revealed the presence of granulomas. But for the caseation and necrosis they were present in 85% cases of nodal tissue biopsies. From those, 56.7% were from females. The presence of acid-fast bacilli was microscopically confirmed by ZN staining in 37 (61.7%) of the nodal tissue biopsies.Conclusion and Recommendation. Tuberculosis lymphadenitis is significantly more common in females. Hence, attention should be given for control and prevention of extrapulmonary tuberculosis.

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Kaczmarkowska, Aleksandra, Anna Didkowska, Sylwia Brzezińska, Daniel Klich, Ewelina Kwiecień, Izabella Dolka, Piotr Kociuba, Magdalena Rzewuska, Ewa Augustynowicz-Kopeć, and Krzysztof Anusz. "Could the type and severity of gross lesions in pig lymph nodes play a role in the detection of Mycobacterium avium?" PLOS ONE 17, no. 7 (July 15, 2022): e0269912. http://dx.doi.org/10.1371/journal.pone.0269912.

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The Mycobacterium avium complex (MAC) comprises a widespread group of slowly-growing bacteria from the Mycobacteriaceae. These bacteria are responsible for opportunistic infections in humans and animals, including farm animals. The aim of the study was to determine whether it is possible to predict the presence of M. avium in pig lymph nodes based on the size and type of lesions found during post-mortem examination at a slaughterhouse. Lymph nodes were collected from 10,600 pigs subjected to such post-mortem examination. The nodes were classified with regard to their quality, and the number of tuberculosis-like lesions; following this, 86 mandibular lymph nodes with lesions and 113 without visible macroscopic lesions were selected for further study. Cultures were established on Löwenstein-Jensen and Stonebrink media, and a commercial GenoType Mycobacterium CM test was used to identify and differentiate M. avium species. The prevalence of M. avium was 56.98% in the lymph nodes with lesions and 19.47% in the unchanged ones. Statistical analysis indicated that visual assessment of lesions in the mandibular lymph nodes, in particular the number of tuberculous lesions, is a highly-efficient diagnostic tool. Similar results were obtained for estimated percentage area affected by the lesion, i.e. the ratio of the changed area of the lymph node in cross-section to the total cross-sectional area of the lymph node; however, this method is more laborious and its usefulness in slaughterhouse conditions is limited. By incising the lymph nodes and assessing the number of tuberculosis-like lesions, it is possible to limit the inclusion of meat from pigs infected with M. avium into the human food chain.

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Süoǧlu, Yusufhan, Burak Erdamar, İsmail Çölhan, O. Sami Katircioǧlu, and Uǧur Çevikbas. "Tuberculosis of the parotid gland." Journal of Laryngology & Otology 112, no. 6 (June 1998): 588–91. http://dx.doi.org/10.1017/s0022215100141180.

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AbstractThe presentation of tuberculosis as an isolated parotid lump is rare. In this paper, six cases with tuberculous parotitis are reported which were evaluated as a benign parotid neoplasm in 216 specimens pre-operatively. All but one of them had no previous history of tuberculosis and all had a parotid lump as a sole symptom for at least one year. The diagnosis of tuberculosis was made, after superficial parotidectomy, by histopathology. Parenchymal involvement and intraparotid lymph node involvement with tuberculosis were seen in five and three patients, respectively. Two of the patients had lymph node involvement outside the parotid area. One of six patients had a coincidental Warthin tumour. A surgical approach is not only therapeutic but also diagnostic when other diagnostic tools fail.

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Al-Ebrahim, Ebrahim K., and Tariq A. Madani. "Multifocal Tuberculosis with Prolonged Paradoxical Reaction." Journal of King Abdulaziz University - Medical Sciences 26, no. 1 (June 30, 2019): 51–57. http://dx.doi.org/10.4197/med.26-1.7.

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This is a case report describing successful treatment of a challenging case of an 18-year old previously healthy high school male student with multifocal tuberculosis involving the spleen and mediastinal and abdominal lymph nodes confirmed by histopathology of splenectomy tissue. The patient initially responded well to antituberculosis therapy with complete resolution of fever and improvement in his general health and weight. However, two months after initiation of anti-tuberculosis therapy, the patient developed paradoxical reaction manifest as recurrence of fever that persisted for five months and was associated with enlargement of lymph nodes. The fever failed to abate with continuation of the same antituberculosis therapy. Despite reassurance that the fever was due to a prolonged paradoxical reaction, a decision was made by the family to seek advice in another hospital where lymphoma was excluded again by histopathological examination of an excisional lymph node biopsy that revealed caseating granulomatous lymphadenitis and negative tuberculosis stain, culture, and polymerase chain reaction. The patient was continued on anti-tuberculosis therapy and treated with corticosteroids that resulted in complete resolution of fever and subsequent full recovery from his tuberculosis.

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Journal articles on the topic 'Lymph Node Tuberculosis'

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