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Dissertations / Theses on the topic 'Lymphatic nodes'

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1

Collinson, Trevor Graham. "Lymphatic visualisation and biopsy in breast cancer /." Title page, contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09MS/09msc713.pdf.

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2

Kokkonen, T. (Tuomo). "Endothelial FasL in lymph nodes and in intestinal lymphatic tissue." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526211312.

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Abstract The function of the transmembrane protein FasL is to complex with the Fas receptor in a target cell and induce target cell apoptosis. Fas/FasL-mediated apoptosis plays important role in immunoregulation. FasL expression is mostly seen in activated lymphocytes. We have characterized endothelial FasL expression in different functional compartments of lymph nodes and gut-associated lymphoid tissue. Furthermore, we have explored the functional role of endothelial FasL expression by analyzing correlation with apoptosis of lymphocyte subpopulations in lymph nodes and by assessing endothelia
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3

Harrell, Joshua C. "Dissecting roles of estrogen receptors in breast cancer lymphatic metastasis /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2007.

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Thesis (Ph.D. in Reproductive Sciences) -- University of Colorado Denver, 2007.<br>Typescript. Includes bibliographical references (leaves 125-140). Free to UCD affiliates. Online version available via ProQuest Digital Dissertations;
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4

Chen, Wanqing. "Predictors of axillary lymph node involvement in screen-detected breast cancer." Connect to full text, 2004. http://setis.library.usyd.edu.au/adt/public_html/adt-NU/public/adt-NU20050104.165451/index.html.

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Thesis (M.I.P.H.)--School of Public Health, University of Sydney, 2004.<br>"This treatise is submitted in partial satisfaction of the requirements for the Degree of Master of International Public Health (Hons), University of Sydney". Bibliography: leaves 10-15.
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5

Malhotra, Deepali. "Insights into the Transcriptional Identities of Lymph Node Stromal Cell Subsets Isolated from Resting and Inflamed Lymph Nodes." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10678.

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Non-hematopoietic stromal cells (SCs) promote and regulate adaptive immunity through numerous direct and indirect mechanisms. SCs construct and support the secondary lymphoid organs (SLOs) in which lymphocytes crawl on stromal networks and inspect antigen-presenting cells for surface-display of cognate antigens. SCs also secrete survival factors and chemotactic cues that recruit, organize, and facilitate interactions among these leukocytes. They influence antigen access by secreting and ensheathing extracellular matrix-based conduit networks that rapidly convey small, soluble lymph-borne molec
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6

Ohara, Patricia Miyuki. "Microbiologia e histopatologia de linfonodos de bovinos com lesões macroscópicas sugestivas de tuberculose. Colheitas efetuadas de Maio/2002 à Janeiro/2004, São Paulo, Brasil." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-17042007-122417/.

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Linfonodos de 146 bovinos com lesões macroscópicas identificadas como sugestivas de tuberculose pelos Serviços de Inspeção Federal e Estadual de abatedouros do Estado de São Paulo, Brasil, no período de Maio de 2002 à Janeiro de 2004, conservadas em solução de borato de sódio em temperatura ambiente por no máximo 60 dias, negativos nos cultivos de micobactérias nos meios de Lowëstein-Jensen e Stonebrink com descontaminação por Petroff e HPC e conservadas por congelamento, foram submetidos a novos cultivos em Agar Sangue, Agar MacConkey e Agar Saboraud bem como ao exame histopatológico pelas co
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7

Marijana, Basta Nikolić. "Magnetnorezonantna sekvenca difuzionog kretanja u proceni metastatske invazije limfnih čvorova kod malignih tumora ženskih polnih organa." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2016. http://www.cris.uns.ac.rs/record.jsf?recordId=101131&source=NDLTD&language=en.

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UVOD: Maligni tumori reproduktivnih organa nalaze se među vodećim uzrocima obolevanja i umiranja od malignih bolesti žena, kako u svetu, tako i u Srbiji. Jedan od najvažnijih puteva &scaron;irenja ovih bolesti je limfogeni, a konvencionalna radiolo&scaron;ka dijagnostika limfnih čvorova kod ovih pacijentkinja je neprecizna. Funkcionalna radiolo&scaron;ka dijagnostika, uključujući i magnentno rezonantnu sekvencu difuzionog kretanja (DWI) i iz nje izvedenu ADC mapu koja omogućava kvantitativnu analizu difuzionih osobina unutar limfnog čvora, daju obećavajuće rezultate u mogućnosti razlikovanja b
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8

Short, Robert Franklin. "Novel approaches in imaging and image-guided therapy microfabrication, quantitative diagnostic methods, and a model of lymphangiogenesis /." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1117553725.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xvi, 218 p.; also includes graphics (some col.). Includes bibliographical references (p. 200-218). Available online via OhioLINK's ETD Center
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9

Shayan, Raheleh. "CXCL12/CXCR4 in embryonic lymphatic vasculature and lymph node formation." Thesis, Aix-Marseille, 2019. http://www.theses.fr/2019AIXM0304.

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Nous avons étudié le rôle de l’axe CXCL12 / CXCR4 dans la période initiale de formation de LN, de E12.5 à E14.5. Nous avons utilisé le modèle rapporteur Cxcl12DsRed et généré des embryons de KO généraux à l'aide de Cxcl12DsRed, ce qui nous a permis d'étudier les effets de cette suppression sur les embryons. Il en résultait beaucoup moins de cellules dans le LN anlagen cervical et mandibulaire, ce qui se reflétait dans la quantité totale de LTi4 dans l'embryon. Nous avons également éliminé Cxcr4 de manière conditionnelle sur les CSH en utilisant des souris Vavicre croisées avec des souris Cxcr4
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10

Zorica, Špirić. "Prognostički značaj tumorske limfangiogeneze kod pacijenata sa melanomom kože." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2016. http://www.cris.uns.ac.rs/record.jsf?recordId=100272&source=NDLTD&language=en.

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Увод: Туморска лимфангиогенеза је подручје активног истраживања у циљу проналаска параметара који би омогућили прецизније предвиђање понашања меланома него што то омогућавају традиционални хистолошки и клинички параметри. Иако су импресивна открића о улози лимфангиогенезе у промовисању метастазирања меланома коже, ипак су остала отворена бројна питања и још увек нису усаглашене препоруке које би биле примењиване у дијагностици и терапији. Циљ истраживања је био испитати да ли параметри лимфангиогенезе и Шилдсов индекс имају значај за прогнозу код пацијената са меланомом коже. Материјал и метод
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11

Harris, Jennifer Nicole. "The role of lymph node-derived lymphatic endothelial cells in immune modulation in the tumour microenvironment." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/287480.

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The lymphatic vasculature is a key player in progression of many cancers, with lymphangiogenesis at the primary tumour and tumour-draining lymph nodes (TDLNs) associated with poor patient prognosis. As well as providing a highway for metastatic tumour cells, recent reports propose lymphatics as modulators of immunity, highlighting a need for greater understanding of immune regulation by lymphatics. The specific role of lymphatic endothelial cells (LECs) in this context, particularly in TDLNs, is unknown. As TDLNs are immune hubs, yet anti-tumour immune responses are often ineffective, this the
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12

Celebioglu, Fuat. "Sentinel node biopsy in breast cancer : aspects on validation, diagnostics and lymphatic drainage pattern /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-772-3/.

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13

Bhattarai, Nihit. "Differentiation Mechanisms of Myeloid-Lymphatic Progenitors that Promote Lymph Node Metastasis in Breast Cancer." OpenSIUC, 2020. https://opensiuc.lib.siu.edu/theses/2657.

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Metastasis to distant organs, a major cause of mortality from cancer, is often preceded by tumor spread to regional lymph nodes (LN). This process is supported exclusively by lymphatic vessels within or around the tumor. It is important to understand the mechanism by which tumors induce generation of new lymphatic vessels because interference with this early stage of tumor spread might prevent distant metastasis. Tumor lymphatic formation is thought to be induced by VEGF-C factor that activates its receptor VEGFR-3 expressed in lymphatic endothelial cells (LEC). However, this process also requ
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14

Vieira, Sabas Carlos. "Identificação de linfonodo sentinela em cancer do colo uterino." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310563.

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Orientador: Luiz Carlos Zeferino<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-12T08:55:33Z (GMT). No. of bitstreams: 1 Vieira_SabasCarlos_D.pdf: 1418388 bytes, checksum: 1d70cc451697cfbd93e48319a0284d4e (MD5) Previous issue date: 2008<br>Resumo: Objetivos: Avaliar a detecção do linfonodo sentinela em pacientes com câncer do colo do útero utilizando a combinação de azul patente com tecnécio99m e complicações associadas ao uso do azul patente. Sujeitos e métodos: Este foi um estudo de uma série de casos, para o qu
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15

Griggs, Caitlin Elizabeth. "Generation of myeloid-derived lymphatic endothelial cell progenitors (M-LECPs) by TLR4-mediated inflammation and de novo VEGFR-3 signaling in breast cancer." OpenSIUC, 2016. https://opensiuc.lib.siu.edu/theses/1902.

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Breast cancer is the second leading cause of cancer-related death in women in the United States. Complications that lead to mortality of cancer patients are associated with tumor metastasis. Specifically, lymphatic metastasis in breast cancer patients strongly correlates with poor patient survival and this process is facilitated by the formation of new tumor lymphatic vessels termed lymphangiogenesis. Previously, our lab reported that lymphangiogenesis was promoted by a distinct subset of bone marrow (BM)-derived myeloid cells that co-express lymphatic-specific markers designated as myeloid-de
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16

Mettu, Ramakanth Reddy. "Constructing gene expression based prognostic models to predict recurrence and lymph node metastasis in colon cancer." Morgantown, W. Va. : [West Virginia University Libraries], 2008. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=6015.

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Thesis (M.S.)--West Virginia University, 2008.<br>Title from document title page. Document formatted into pages; contains xiv, 126 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 123-126).
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17

Karlsson, Mona. "Sentinel node based immunotherapy of cancer /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-203-3/.

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18

Mumprecht, Viviane Denise. "In vivo imaging of tumor- and inflammation-induced lymph node lymphangiogenesis and proteomic profiling for the identification of surface-accessible lymphatic markers /." [S.l.] : [s.n.], 2009. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=18414.

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19

Lloyd, Shane. "A Prognostic Index for Predicting Lymph Node Metastasis in Minor Salivary Gland Cancer." Yale University, 2009. http://ymtdl.med.yale.edu/theses/available/etd-03052009-215912/.

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We hypothesized that lymph node involvement in minor salivary gland cancers is associated with clinical and pathological factors commonly available to the clinician after a typical initial workup. Our aim was to identify these factors using a dataset that allowed us to compile the largest series of minor salivary gland cancers in the published literature. Using this dataset we also aimed to characterize the distribution of histological types by primary site, identify the predictors of the use of external beam radiation therapy and neck dissection, and examine the effect of lymph node involveme
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20

Ilija, Baroš. "Молекуларна и генска хетерогеност метастаза у аксиларним лимфним чворовима код пацијенткиња са инвазивним карциномом дојке". Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=110238&source=NDLTD&language=en.

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HER2 Gene-Protein Assay (GPA) је посебно погодан за истовремено процењивање експресије HER2 протеина и статуса амплификације HER2 гена на нивоу појединачних ћелија и њихово повезивање са ћелијском морфологијом. Циљ истраживања био је испитати да ли су постојећи критеријуми препоручени од стране ASCO/CAP довољни за дијагностиковање HER2 позитивности код пацијенткиња које показују интратуморску хетерогеност, како у примарним туморима тако и у метастазама у регионалне лимфне чворове, учесталост HER2 хетерогености у макрометастазама лоцираним у лимфним чворовима, те да ли постоји јасна корелација
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21

Granzotto, Talitha Marmorato. "Caracterização dos padrões de drenagem linfática nas linfocintilografias de amostra de pacientes com melanoma." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/82/82131/tde-13102011-091616/.

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A linfocintilografia tem contribuído muito para a visualização da drenagem linfática e linfonodo sentinela (LNS) acometido e o estado patológico do LNS é considerado o fator prognóstico mais importante do melanoma. Os objetivos deste trabalho foram descrever os padrões de drenagem linfática em pacientes operados por melanoma, avaliar as características clínicas, demográficas e cirúrgicas destes pacientes, assim como a contribuição da Linfocintilografia na localização dos LNS com vistas à biópsia do mesmo. Foram avaliados 29 pacientes com melanoma operados, e a Linfocintilografia pré-operatória
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Dahl, Kjell. "Human colorectal cancer : experimental staging and therapeutics /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-154-8/.

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23

Melo, Jose Ricardo de Moura Torres de. "Modelo Experimental em Caninos para a Pesquisa de Linfonodo Sentinela do EstÃmago." Universidade Federal do CearÃ, 2010. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=4883.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>A gastrectomia com linfadenectomia ampliada ainda à o padrÃo ouro para o tratamento curativo do cÃncer de estÃmago (CaE), embora este procedimento possa levar a alto Ãndice de morbidade ou mortalidade, principalmente nos pacientes que nÃo apresentem disseminaÃÃo linfÃtica da doenÃa. A pesquisa do linfonodo sentinela (LS), jà consagrada nos tumores iniciais de mama e nos melanomas, apresenta-se cada vez mais freqÃente no trato digestÃrio, em especial no CaE com resultados animadores. Estudos iniciados nos meados do ano 2000 retrata
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Souza, Fernando Wiecheteck de. "Linfadenectomia inguinoilíaca videolaparoscópica em cadelas após impregnação com diferentes marcadores linfáticos." Universidade Federal de Santa Maria, 2014. http://repositorio.ufsm.br/handle/1/4100.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Laparoscopic pelvic lymphadenectomy has been performed routinely in medicine, using injectable lymphatic markers for delineation of lymphatic tissue and promoting free surgical margins of resection in tumor tissues. This practice also has therapeutic and diagnostic purposes when the pelvic lymph nodes are tumor-chain, resulting in a better prognosis for patients with certain types of cancer. Lymphadenectomy also aids in the diagnosis of regional metastases in other organs as well as in establishing the type of therapy to be adopted
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Chypre, Mélanie. "Role of receptor activator of NF-kB ligand (RANKL) in adult lymph node homeostasis and identification of inhibitors." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAJ016/document.

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Le récepteur activateur de NF-κB (RANK), membre de la famille des récepteurs au TNF, est connu pour son rôle dans l’homéostasie de l’os, mais joue aussi un rôle important dans le système immunitaire. J’ai tout d’abord étudié des outils permettant de cibler RANK/RANKL. J’ai caractérisé et comparé l’activité biologique de deux anticorps anti-RANK. J’ai également criblé une librairie de petites molécules pour identifier des inhibiteurs de l’interaction RANK/RANKL. Dans une deuxième partie, je me suis intéressée au rôle du ligand de RANK (RANKL) dans l’homéostasie du ganglion lymphatique. RANKL jo
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Quadros, Claudio de Almeida. "Linfonodectomia retroperitoneal e pélvica lateral guiada por radiotraçador e azul patente no estadiamento do adenocarcinoma do reto." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-09122009-152351/.

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INTRODUÇÃO: A excisão total do mesorreto é o procedimento cirúrgico padrão para o tratamento do adenocarcinoma do reto. Resultados satisfatórios, em termos de prognóstico, alcançados com a associação da linfonodectomia retroperitoneal e pélvica lateral questionam se somente a excisão total do mesorreto seria suficiente para um estadiamento adequado, podendo afetar decisões relacionadas ao tratamento adjuvante. Este estudo avaliou o impacto das metástases em linfonodos retroperitoneais e/ou pélvicos laterais na mudança do estadiamento de pacientes com adenocarcinoma do reto e a acurácia da iden
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27

Oliveira, Junior Idam de. "Pesquisa do linfonodo sentinela em pacientes portadoras de tumores de mama T3 e T4 Análise em hospital terciário oncológico e revisão sistemática da literatura. /." Botucatu, 2019. http://hdl.handle.net/11449/181087.

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Orientador: René Aloísio da Costa Vieira<br>Resumo: Introdução: O câncer de mama representa o tipo de câncer mais comum entre as mulheres no mundo. A presença e a extensão do envolvimento linfonodal axilar é um importante fator prognóstico, com grande impacto na decisão terapêutica. Por outro lado, a linfadenectomia axilar (LA) associa-se a considerável morbidade. Neste sentido, a biópsia do linfonodo sentinela (BLS) constitui modalidade atualmente aceita para uso em tumores T1 e T2, associados a axila negativa. Fato é que pacientes com tumores T3 e T4 e axila negativa são, muitas vezes, subme
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El, Hajj Petra. "New prognosis markers and new targets for therapy in high risk melanoma: evaluation of TYRP1 as a melanoma prognostic marker and its regulation by miRNA(s)." Doctoral thesis, Universite Libre de Bruxelles, 2015. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209064.

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L’espérance de vie des patients atteints de mélanome à haut risque ne peut être prédite d’une façon<p>fiable en se basant sur les analyses d’histopathologies de la lésion primitive et est souvent ajustée<p>durant la progression de la maladie. Notre étude vise à élargir nos observations initiales au niveau<p>des métastases cutanées et d’évaluer la valeur pronostique de tyrosinase related protein 1 (TYRP1)<p>dans les métastases ganglionnaires des patients atteints de mélanome de stades III et IV. TYRP1 est<p>une enzyme mélanosomale qui partage des similitudes structurelles avec la tyrosinase, l'
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Steck, José Higino. "Validade do mapeamento do linfonodo sentinela na detecção de metástase linfática cervical do carcinoma papilífero da glândula tireoide." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-06092016-145112/.

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INTRODUÇÃO: O mapeamento do linfonodo sentinela (MLNS) é largamente utilizado em pacientes com melanoma cutâneo, câncer de mama e outras neoplasias malignas sólidas com a finalidade de estadiá-las e indicar esvaziamento linfático apenas na presença de metástase. Nos últimos anos aumentou o interesse pelo uso do MLNS em pacientes com carcinoma papilífero de tireoide (CPT) sem metástases linfáticas detectáveis clinicamente (estádio cN0), devido à alta frequência de metástases ocultas nesses pacientes. O MLNS pode evitar o esvaziamento linfático do compartimento central (ECC) em portadores de CPT
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Fernandes, Margareth da Rocha. ""Contribuição ao estudo da influência da radiação ionizante pré-operatória sobre a marcação do linfonodo sentinela do reto com azul patente: estudo experimental em ratos"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-17042006-103113/.

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A radiação ionizante prévia promove alterações actínicas em tecidos peritumorais,o que poderia influenciar a demarcação do linfonodo sentinela.O presente estudo desenvolveu modelo experimental para demarcação do linfonodo sentinela do reto do rato e para definição da dose de radiação (curva de calibração). O objetivo foi avaliar a influência da radiação ionizante pré-operatória sobre a marcação, com corante azul patente, do linfonodo sentinela do reto de ratos. A amostra foi constituída por 40 ratos machos Wistar e dividida em 2 grupos:Grupo 1 (controle não irradiado; n = 20) e Grupo 2 (irradi
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Kunder, Christian. "Interactions of Mast Cells with the Lymphatic System: Delivery of Peripheral Signals to Lymph Nodes by Mast Cell-Derived Particles." Diss., 2009. http://hdl.handle.net/10161/1307.

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<p>Mast cells, best known for their pathologic role in allergy, have recently been shown to have key roles in the initiation of adaptive immune responses. These cells are located throughout the body just beneath barriers separating host from environment, possess multiple pathogen recognition systems, and store large quantities of fully active inflammatory mediators. These key features make them uniquely situated to act as sentinels of immunity, releasing the very earliest alarm signals when a pathogen is present. As a testament to the importance of these cells, mast cell-deficient mice have
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Breymann, Carolin Sophie. "Die lymphatischen Abflusswege von Gehirn und Hypophyse im Mausmodell." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0028-86D2-2.

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Die vorliegende Arbeit diente vor allem der Untersuchung, ob es im Gehirn vergleichbare Lymphabflusswege wie im übrigen Körper gibt und falls dies zutrifft, wo diese Abflusswege des Gehirns verlaufen. Denn für größere Proteine und Moleküle müsste es eine geeignete Route geben, um das ZNS verlassen zu können, da diese zum Passieren der Bluthirnschranke (BHS) zu groß sind. In dieser Arbeit konnte erstmals gezeigt werden, dass es auch eine Art lymphatischen Drainageweg aus der Hypophyse (HVL = Adenohypophyse) zu den tiefen und superfizialen, zervikalen Lymphknoten gibt. Daneben konnten auch die A
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Liu, Jiang. "Controlled Trans-lymphatic Delivery of Chemotherapy for the Treatment of Lymphatic Metastasis in Lung Cancer." Thesis, 2008. http://hdl.handle.net/1807/11115.

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Lymph node metastasis is a critical prognostic factor for lung cancer. Effective therapy to control lymphatic metastasis may improve survival. The work described in this thesis focuses on the development of a microparticulate lymphatic targeting system, which can be applied as an adjuvant therapy in the control of lymphatic metastasis in lung cancer. The study shows that intrapleural administered colloidal particulates are predominantly taken up by regional lymphatic tissue in rat models including healthy rats, rats bearing orthotopic lung tumours and rats following pneumonectomy. The eff
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Louis, Kristine Sarah. "Characterization of ZHX1 in Axillary Lymph Node-negative Breast Cancer." Thesis, 2012. http://hdl.handle.net/1807/32603.

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Women with breast cancer without local metastasis to the axillary lymph nodes (axillary lymph node-negative, ANN) have a good prognosis. However, 20 to 30% of patients with ANN breast cancer will still experience recurrence and distant metastases. Lymphatic invasion (LVI) is an important prognostic factor for ANN breast cancer. Zinc fingers and homeoboxes 1 (ZHX1) was identified as a candidate gene involved in LVI and associated with early recurrence of ANN breast cancer. I examined expression of ZHX1 in breast cancer cell lines and ANN breast tumour samples and discovered that it is expressed
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35

Charvát, Martin. "Rizika a limity laparoskopie v léčbě gynekologických zhoubných nádorů." Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-353585.

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The thesis evaluates the results of experimental protocol involving the fertility sparing treatment procedure in early stage cervical carcinoma (LAP I protocol). Sentinel lymph node detection and experimental extirpation of afferent channels using laparoscopy and its technical aspects were analysed in prospective group of 85 women. The oncologic results and early/late morbidity show that established surgical procedures can be considered safe with minimal morbidity, provided that the indication criteria are met. The second part analyses the results of 148 women with no further pregnancy plans s
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36

Kocián, Roman. "Význam biopsie sentinelové uzliny v léčbě pacientek s časným stádiem karcinomu děložního hrdla." Doctoral thesis, 2021. http://www.nusl.cz/ntk/nusl-447348.

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The sentinel lymph node biopsy is part of recommended surgical staging guidelines in patients with early stages of cervical cancer. High success rates of bilateral detection of SLN are achieved in sites with adequate experience with this procedure. The sentinel lymph node biopsy without systematic pelvic lymph node dissection is currently considered inadequate procedure for stages IB to IIA of the disease. One of the benefits of sentinel lymph node detection is extensive histopathological examination using the ultrastaging protocol enabling detection of small metastases (i.e. micrometastases).
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