Log in

Relevant bibliographies by topics / Lymphatic nodes / Journal articles

To see the other types of publications on this topic, follow the link: Lymphatic nodes.

Journal articles on the topic 'Lymphatic nodes'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Lymphatic nodes.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Szuba, Andrzej, and Stanley G. Rockson. "Lymphedema: Anatomy, Physiology and Pathogenesis." Vascular Medicine 2, no. 4 (1997): 321–26. http://dx.doi.org/10.1177/1358863x9700200408.

Full text

Abstract:

The authors review the current understanding of lymphatic anatomy and physiology, and the pathophysiology of lymphedema. The skin lymphatic system consists of the initial lymphatics, which converge into lymphatic precollectors, collectors and lymphatic ducts; these in turn convey the lymph to the regional lymph nodes. Interstitial fluid and particles enter the initial lymphatics through interendothelial openings and by vesicular transport. Lymphatic uptake is enhanced by external compression. Lymphatic transport depends greatly on contraction of lymphangions, which generate the suction force t

APA, Harvard, Vancouver, ISO, and other styles

2

Jakovija, Arnolda, and Tatyana Chtanova. "Neutrophil Interactions with the Lymphatic System." Cells 10, no. 8 (2021): 2106. http://dx.doi.org/10.3390/cells10082106.

Full text

Abstract:

The lymphatic system is a complex network of lymphatic vessels and lymph nodes designed to balance fluid homeostasis and facilitate host immune defence. Neutrophils are rapidly recruited to sites of inflammation to provide the first line of protection against microbial infections. The traditional view of neutrophils as short-lived cells, whose role is restricted to providing sterilizing immunity at sites of infection, is rapidly evolving to include additional functions at the interface between the innate and adaptive immune systems. Neutrophils travel via the lymphatics from the site of inflam

APA, Harvard, Vancouver, ISO, and other styles

3

Abernethy, N. J., W. Chin, J. B. Hay, H. Rodela, D. Oreopoulos, and M. G. Johnston. "Lymphatic drainage of the peritoneal cavity in sheep." American Journal of Physiology-Renal Physiology 260, no. 3 (1991): F353—F358. http://dx.doi.org/10.1152/ajprenal.1991.260.3.f353.

Full text

Abstract:

Lymphatic drainage of the peritoneal cavity has been investigated in anesthetized sheep. Studies involving intraperitoneal administration of a complex of Evans blue dye and bovine serum albumin demonstrated the existence of three anatomically distinct pathways. In the first pathway, dye is removed from the peritoneal cavity by diaphragmatic lymphatics that pass into caudal sternal lymph nodes. Efferent lymphatics from these nodes transport the material to cranial sternal lymph nodes. Efferent cranial sternal lymphatics then convey the material either directly or indirectly, via tracheal lympha

APA, Harvard, Vancouver, ISO, and other styles

4

Iftakhar-E-Khuda, Imtiaz, Ruth Fair-Mäkelä, Anu Kukkonen-Macchi, et al. "Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic." Proceedings of the National Academy of Sciences 113, no. 38 (2016): 10643–48. http://dx.doi.org/10.1073/pnas.1602357113.

Full text

Abstract:

Afferent lymphatic vessels bring antigens and diverse populations of leukocytes to draining lymph nodes, whereas efferent lymphatics allow only lymphocytes and antigens to leave the nodes. Despite the fundamental importance of afferent vs. efferent lymphatics in immune response and cancer spread, the molecular characteristics of these different arms of the lymphatic vasculature are largely unknown. The objective of this work was to explore molecular differences behind the distinct functions of afferent and efferent lymphatic vessels, and find possible molecules mediating lymphocyte traffic. We

APA, Harvard, Vancouver, ISO, and other styles

5

Dabney, J. M., M. J. Buehn, and D. E. Dobbins. "Constriction of lymphatics by catecholamines, carotid occlusion, or hemorrhage." American Journal of Physiology-Heart and Circulatory Physiology 255, no. 3 (1988): H514—H524. http://dx.doi.org/10.1152/ajpheart.1988.255.3.h514.

Full text

Abstract:

Regulation of lymphatics by sympathetic nerves or hormones seems probable. To elucidate this, we perfused a lymphatic vessel in the paw of the anesthetized dog while measuring lymphatic perfusion pressure. We studied the effects of norepinephrine, epinephrine, hemorrhage, and carotid occlusion on lymphatic pressure. Blood was pumped to the forelimb via the brachial artery. Cannulas were placed to measure systemic, central venous, and forelimb vascular pressures. Catecholamines, whether added to the lymphatic perfusate or infused into the forelimb arterial blood, and bilateral carotid occlusion

APA, Harvard, Vancouver, ISO, and other styles

6

Scaglioni, Mario, and Hiroo Suami. "Anatomy of the Lymphatic System and the Lymphosome Concept with Reference to Lymphedema." Seminars in Plastic Surgery 32, no. 01 (2018): 005–11. http://dx.doi.org/10.1055/s-0038-1635118.

Full text

Abstract:

AbstractPrecise knowledge of the lymphatic system normal anatomy is essential for understanding what structural changes occur in patients with lymphedema. In this article, the authors first review previous anatomical studies and summarize the general anatomy of the lymphatic system and lymphatic pathways in the upper and lower extremities. Second, they introduce their new anatomical concept, the “lymphosome,” which describes how the lymphatic vessels in a particular region connect to the same subgroup of regional lymph nodes. In addition, they describe the anatomical relationship between the p

APA, Harvard, Vancouver, ISO, and other styles

7

Singh, A., D. N. Ezeasor, and N. K. Sidhu. "Ultrastructure of lymphatic endothelium." Proceedings, annual meeting, Electron Microscopy Society of America 47 (August 6, 1989): 924–25. http://dx.doi.org/10.1017/s0424820100156602.

Full text

Abstract:

Recently, the lymphatics in the caprine hemal nodes have been described. The present study describes some ultrastructural features of the endothelium in the lymphatics of the goat hemal nodes.Hemal nodes located along the aorta, were collected from 15 clinically healthy, adult, West African dwarf goats. The tissues were fixed by either immersion or perfusion methods. For immersion fixation, the nodes were excised, and immersed temporarily in cold 2.5% glutaraldehyde in 0. IM cacodylate buffer, pH 7.3. After 5 min, the nodes were diced into 1-2 mm cubes and further fixed for 2 h in the same fix

APA, Harvard, Vancouver, ISO, and other styles

8

Akita, Shinsuke, Yoshihisa Yamaji, Motone Kuriyama, et al. "Intraoperative Detection of Efferent Lymphatic Vessels Emerging from Lymph Node during Lymphatic Microsurgery." Journal of Reconstructive Microsurgery 35, no. 05 (2019): 372–78. http://dx.doi.org/10.1055/s-0038-1677039.

Full text

Abstract:

Background Although the usefulness of efferent lymphaticovenular anastomosis (ELVA) in lymphatic microsurgery has been reported, the optimal method to distinguish efferent from afferent lymphatics is not yet established. We propose a novel technique to detect efferent lymphatics appropriate for anastomosis. Methods In total, 62 groin lymph nodes (LNs) of 46 limbs were divided into four groups based on the findings of indocyanine green lymphography: n = 15 in normal, 15 in dermal backflow stage 0, 18 in stage I, and 14 in stage II groups. The target LN and afferent lymphatic connecting it were

APA, Harvard, Vancouver, ISO, and other styles

9

Cesmebasi, Alper, Amanda Baker, Maira Du Plessis, Petru Matusz, R. Shane Tubbs, and Marios Loukas. "The Surgical Anatomy of the Inguinal Lymphatics." American Surgeon 81, no. 4 (2015): 365–69. http://dx.doi.org/10.1177/000313481508100426.

Full text

Abstract:

Knowledge of the lymphatic system plays critical importance in surgical oncology. The study of the lymphatic system and its role in tumor metastasis continues to advance with new anatomical and surgical studies, and with a new study, we can gain a better understanding on how aggressive surgeons need to be with nodal dissection while balancing the complications with overly aggressive approaches. The lymphatics of the inguinal region represent a network of lymph nodes and vessels, which act as the bridge among the lower extremities, pelvis, perineum, and rest of the body. These lymph nodes are o

APA, Harvard, Vancouver, ISO, and other styles

10

Keramida, Georgia, Emma Wroe, Nicola Winterman, Mark Aplin, and A. Michael Peters. "Lymphatic drainage efficiency: a new parameter of lymphatic function." Acta Radiologica 59, no. 9 (2017): 1097–101. http://dx.doi.org/10.1177/0284185117744226.

Full text

Abstract:

Background Following convection from blood capillaries, plasma proteins are transported to loco-regional lymph nodes in two stages: first, uptake into peripheral lymphatics, and second, transport to nodes. Purpose To introduce a new parameter of lymphatic function that quantifies stage 2 – lymphatic drainage efficiency (LDE). Material and Methods Percentage injected activity (IIQ) in ilio-inguinal nodes 150 min following subcutaneous foot web-space injection of Tc-99 m-nanocolloid was measured in 102 patients undergoing lymphoscintigraphy using a method in which a standard is placed by image g

APA, Harvard, Vancouver, ISO, and other styles

11

Minsker, O. B., and L. B. Golov. "Actinomycosis of Lymphatic Nodes." Mycoses 21, no. 7 (2009): 223–35. http://dx.doi.org/10.1111/j.1439-0507.1978.tb01643.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Bovay, Esther, Amélie Sabine, Borja Prat-Luri, et al. "Multiple roles of lymphatic vessels in peripheral lymph node development." Journal of Experimental Medicine 215, no. 11 (2018): 2760–77. http://dx.doi.org/10.1084/jem.20180217.

Full text

Abstract:

The mammalian lymphatic system consists of strategically located lymph nodes (LNs) embedded into a lymphatic vascular network. Mechanisms underlying development of this highly organized system are not fully understood. Using high-resolution imaging, we show that lymphoid tissue inducer (LTi) cells initially transmigrate from veins at LN development sites using gaps in venous mural coverage. This process is independent of lymphatic vasculature, but lymphatic vessels are indispensable for the transport of LTi cells that egress from blood capillaries elsewhere and serve as an essential LN expansi

APA, Harvard, Vancouver, ISO, and other styles

13

Dabney, J. M., M. J. Buehn, and D. E. Dobbins. "Perfused prenodal lymphatics are constricted by prostaglandins." American Journal of Physiology-Heart and Circulatory Physiology 260, no. 1 (1991): H1—H5. http://dx.doi.org/10.1152/ajpheart.1991.260.1.h1.

Full text

Abstract:

Prostaglandins may contribute to the control of lymph flow by affecting lymphatic vessel contractility. We measured the pressure in perfused prenodal lymphatic vessel in the paw of the anesthetized dog as affected by administration of prostaglandins E1, E2, F2 alpha or arachidonic acid. The forelimb was perfused at constant flow with blood obtained from a femoral artery. Systemic arterial, central venous, and forelimb vascular pressures were measured. When added to the lymphatic perfusate, all of the prostaglandins and arachidonic acid caused constriction of lymphatic vessels. Perfusion of pre

APA, Harvard, Vancouver, ISO, and other styles

14

Ålgars, Annika, Marika Karikoski, Gennady G. Yegutkin, et al. "Different role of CD73 in leukocyte trafficking via blood and lymph vessels." Blood 117, no. 16 (2011): 4387–93. http://dx.doi.org/10.1182/blood-2010-11-321646.

Full text

Abstract:

Abstract CD73 is involved in the extracellular ATP metabolism by dephosphorylating extracellular AMP to adenosine and thus regulating permeability of the blood vessels and leukocyte traffic into the tissues. It is also present on lymphatic vessels where its distribution and function have not been characterized. We found that CD73 is expressed on a subpopulation of afferent lymph vessels but is absent on efferent lymphatics, unlike LYVE-1 and podoplanin, which are expressed on both types of lymphatics. The extracellular nucleotide metabolism on lymphatic endothelium differs from that on blood v

APA, Harvard, Vancouver, ISO, and other styles

15

Loginov, Konstantin, and Nikolai Pertsev. "Stochastic compartmental model of HIV-1 infection." ITM Web of Conferences 31 (2020): 02003. http://dx.doi.org/10.1051/itmconf/20203102003.

Full text

Abstract:

Stochastic model of the dynamics of HIV-1 infection describing the interaction of target cells and viral particles in the lymphatic nodes and their movement between the lymphatic nodes is constructed. The lymphatic system is represented as a graph, vertices of which are the lymphatic nodes and edges are the lymphatic vessels. The novelty of the model consists in the description of populations of cells and viral particles in terms of a multidimensional birth and death process with the random point-distributions. The random pointdistributions describe the duration of the transition of cells and

APA, Harvard, Vancouver, ISO, and other styles

16

Lobov, G. I., and D. V. Unt. "Glucocorticoids stimulate the contractile activity of lymphatic vessels and lymph nodes." Regional blood circulation and microcirculation 16, no. 4 (2017): 73–79. http://dx.doi.org/10.24884/1682-6655-2017-16-4-73-79.

Full text

Abstract:

Objective. The lymphatic network participates in the launch and development of an immune response. From an immunological point of view, the lymph flow, provided by active contractions of the lymphatic vessels, is the process of delivering antigens and antigen-presenting cells to the lymph nodes. The purpose of this study is to study the non-genomic effects and mechanisms of action of glucocorticoids, which are natural immunomodulators, on the transport function of lymphatic vessels and lymph nodes. Materials and methods. Bovine mesenteric afferent lymphatic vessels 1.2-1.5 mm in diameter and l

APA, Harvard, Vancouver, ISO, and other styles

17

Petrova, Tatiana V., and Gou Young Koh. "Organ-specific lymphatic vasculature: From development to pathophysiology." Journal of Experimental Medicine 215, no. 1 (2017): 35–49. http://dx.doi.org/10.1084/jem.20171868.

Full text

Abstract:

Recent discoveries of novel functions and diverse origins of lymphatic vessels have drastically changed our view of lymphatic vasculature. Traditionally regarded as passive conduits for fluid and immune cells, lymphatic vessels now emerge as active, tissue-specific players in major physiological and pathophysiological processes. Lymphatic vessels show remarkable plasticity and heterogeneity, reflecting their functional specialization to control the tissue microenvironment. Moreover, alternative developmental origins of lymphatic endothelial cells in some organs may contribute to the diversity

APA, Harvard, Vancouver, ISO, and other styles

18

Mirilas, Petros, and John E. Skandalakis. "Surgical Anatomy of the Retroperitoneal Spaces, Part III: Retroperitoneal Blood Vessels and Lymphatics." American Surgeon 76, no. 2 (2010): 139–44. http://dx.doi.org/10.1177/000313481007600203.

Full text

Abstract:

In this article, we discuss the surgical anatomy of the blood vessels and the lymphatic vessels and lymph nodes found in the retroperitoneum. Retroperitoneal blood vessels include the aorta and all its branches—parietal and visceral—from the diaphragm to the pelvis, and the inferior vena cava and its tributaries. The retroperitoneal lymphatics form a very rich and extensive chain. As a general rule, lymphatics follow the arteries and named lymph nodes are found at the root of the arteries. Retroperitoneal nodes of the abdomen comprise the inferior diaphragmatic nodes and the lumbar nodes. The

APA, Harvard, Vancouver, ISO, and other styles

19

Ma, Xiaokai, Shishuai Wen, Baofeng Liu, et al. "Relationship between Upper Extremity Lymphatic Drainage and Sentinel Lymph Nodes in Patients with Breast Cancer." Journal of Oncology 2019 (April 1, 2019): 1–7. http://dx.doi.org/10.1155/2019/8637895.

Full text

Abstract:

Purpose. The purpose of this study was to identify the relationship between upper extremity lymphatics and sentinel lymph nodes (SLNs) in breast cancer patients.Methods. Forty-four patients who underwent axillary reverse mapping (ARM) during axillary lymph node dissection (ALND) with SNL biopsy (SLNB) between February 2017 and October 2017 were investigated. ARM was performed using indocyanine green (ICG) to locate the upper extremity lymphatics; methylene blue dye was injected intradermally for SLN mapping.Results. ARM nodes were found in the ALND fields of all examined patients. The rate of

APA, Harvard, Vancouver, ISO, and other styles

20

Yağmurlu, Kaan, Jennifer D. Sokolowski, Musa Çırak, et al. "Anatomical Features of the Deep Cervical Lymphatic System and Intrajugular Lymphatic Vessels in Humans." Brain Sciences 10, no. 12 (2020): 953. http://dx.doi.org/10.3390/brainsci10120953.

Full text

Abstract:

Background: Studies in rodents have re-kindled interest in the study of lymphatics in the central nervous system. Animal studies have demonstrated that there is a connection between the subarachnoid space and deep cervical lymph nodes (DCLNs) through dural lymphatic vessels located in the skull base and the parasagittal area. Objective: To describe the connection of the DCLNs and lymphatic tributaries with the intracranial space through the jugular foramen, and to address the anatomical features and variations of the DCLNs and associated lymphatic channels in the neck. Methods: Twelve formalin

APA, Harvard, Vancouver, ISO, and other styles

21

Das, Suvendu, Eliana Sarrou, Simona Podgrabinska, et al. "Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses." Journal of Experimental Medicine 210, no. 8 (2013): 1509–28. http://dx.doi.org/10.1084/jem.20111627.

Full text

Abstract:

Lymphatic vessels are thought to contribute to metastasis primarily by serving as a transportation system. It is widely believed that tumor cells enter lymph nodes passively by the flow of lymph. We demonstrate that lymph node lymphatic sinuses control tumor cell entry into the lymph node, which requires active tumor cell migration. In human and mouse tissues, CCL1 protein is detected in lymph node lymphatic sinuses but not in the peripheral lymphatics. CCR8, the receptor for CCL1, is strongly expressed by human malignant melanoma. Tumor cell migration to lymphatic endothelial cells (LECs) in

APA, Harvard, Vancouver, ISO, and other styles

22

Бураева and Zarina Buraeva. "Comparative characteristic of lymphatic channels of the regional lymphatic nodes in the small pelvis of women during the reproductive and postmenopausal periods." Vladikavkaz Medico-Biological Bulletin 21, no. 31 (2015): 48–50. http://dx.doi.org/10.12737/17246.

Full text

Abstract:

The results present the investigation of the state of the lymphatic channel of the regional lymphatic notes of the small pelvis of the 36 women at the aged aspect. With the use of all histologic methods with subsequent stereometric assessment of volume density of the lymphatic sinuses of lymphatic nodes, it is shown that the drainage function of the lymphatic nodes in post-climacteric period was much lower, than in women of childbearing period.

APA, Harvard, Vancouver, ISO, and other styles

23

González-Loyola, Alejandra, Esther Bovay, Jaeryung Kim, et al. "FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure." Science Advances 7, no. 29 (2021): eabf4335. http://dx.doi.org/10.1126/sciadv.abf4335.

Full text

Abstract:

The mechanisms maintaining adult lymphatic vascular specialization throughout life and their role in coordinating inter-organ communication to sustain homeostasis remain elusive. We report that inactivation of the mechanosensitive transcription factor Foxc2 in adult lymphatic endothelium leads to a stepwise intestine-to-lung systemic failure. Foxc2 loss compromised the gut epithelial barrier, promoted dysbiosis and bacterial translocation to peripheral lymph nodes, and increased circulating levels of purine metabolites and angiopoietin-2. Commensal microbiota depletion dampened systemic pro-in

APA, Harvard, Vancouver, ISO, and other styles

24

Vuković, Snježana, H. Lucić, H. Gomerčić, et al. "Morphology of the lymph nodes in bottlenose dolphin (Tursiops truncatus) and striped dolphin (Stenella coeruleoalba) from the Adriatic Sea." Acta Veterinaria Hungarica 53, no. 1 (2005): 1–11. http://dx.doi.org/10.1556/avet.53.2005.1.1.

Full text

Abstract:

Morphology of the lymph nodes was examined in six bottlenose dolphins (Tursiops truncatus) and three striped dolphins (Stenella coeruleoalba) from the Adriatic Sea. All animals had been found dead in nature. One group of the nodes was taken from the tracheal branching area and was marked as bifurcational lymph node, and the other group was taken from the mesenteric root and was marked as mesenteric lymph node. Microscopic analysis showed that the lymph nodes in both dolphin specieswere surrounded by a connective tissue capsule comprising smooth muscle cells. The parenchyma of the mesenteric an

APA, Harvard, Vancouver, ISO, and other styles

25

Morton, D. L., D. R. Wen, L. J. Foshag, R. Essner, and A. Cochran. "Intraoperative lymphatic mapping and selective cervical lymphadenectomy for early-stage melanomas of the head and neck." Journal of Clinical Oncology 11, no. 9 (1993): 1751–56. http://dx.doi.org/10.1200/jco.1993.11.9.1751.

Full text

Abstract:

PURPOSE We developed intraoperative lymphatic mapping with selective lymphadenectomy (SLND) to identify micrometastatic spread of cutaneous melanoma to regional lymph nodes. This study was undertaken to assess the sensitivity and specificity of our technique in patients with clinical stage I (CS-I) melanoma of the head or neck. PATIENTS AND METHODS Seventy-two CS-I melanoma patients underwent intraoperative lymphatic mapping of primary cutaneous melanomas located on the head, neck, or upper chest/back draining to the neck. Key (sentinel) cervical lymph nodes in the regional lymphatic drainage

APA, Harvard, Vancouver, ISO, and other styles

26

Basaraba, Randall J., Erin E. Smith, Crystal A. Shanley, and Ian M. Orme. "Pulmonary Lymphatics Are Primary Sites of Mycobacterium tuberculosis Infection in Guinea Pigs Infected by Aerosol." Infection and Immunity 74, no. 9 (2006): 5397–401. http://dx.doi.org/10.1128/iai.00332-06.

Full text

Abstract:

ABSTRACT Mycobacterium tuberculosis causes a lymphatic vasculitis in the lungs of guinea pigs infected by a low-dose aerosol. This observation suggests that in addition to being a direct conduit from the lungs to the regional lymph nodes, pulmonary lymphatics are themselves sites of infection and could be the site of latent infection.

APA, Harvard, Vancouver, ISO, and other styles

27

Marone, Ugo, Luigi Aloj, Gianluca Di Monta, and Corrado Caracò. "Lymphoscintigraphy Defines New Lymphatic Pathways from Cutaneous Melanoma Site: Clinical Implications and Surgical Management." Radiology Research and Practice 2011 (2011): 1–5. http://dx.doi.org/10.1155/2011/817043.

Full text

Abstract:

Sentinel lymph node biopsy is commonly applied as staging procedure of regional lymph nodes in patients with cutaneous melanoma. Dynamic lymphoscintigraphy defines the lymphatic pathways from a primary melanoma site and allows to identify the node receiving lymphatic drainage from the primary tumor, which is the sentinel lymph node. In rare cases, lymphoscintigraphy shows sites of lymphatic drainage in nonclassical basins never described in the past when lymphatic drainage was considered only according to the anatomical proximity of the tumor primary site. These peculiar sentinel nodes, so-cal

APA, Harvard, Vancouver, ISO, and other styles

28

Marttila-Ichihara, Fumiko, Raisa Turja, Mari Miiluniemi, et al. "Macrophage mannose receptor on lymphatics controls cell trafficking." Blood 112, no. 1 (2008): 64–72. http://dx.doi.org/10.1182/blood-2007-10-118984.

Full text

Abstract:

Abstract Macrophage mannose receptor (MR) participates in pathogen recognition, clearance of endogenous serum glycoproteins, and antigen presentation. MR is also present on lymphatic vessels, where its function is unknown. Here we show that migration of lymphocytes from the skin into the draining lymph nodes through the afferent lymphatics is reduced in MR-deficient mice, while the structure of lymphatic vasculature remains normal in these animals. Moreover, in a tumor model the primary tumors grow significantly bigger in MR−/− mice than in the wild-type (WT) controls, whereas the regional lym

APA, Harvard, Vancouver, ISO, and other styles

29

Tal, Orna, Hwee Ying Lim, Irina Gurevich, et al. "DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling." Journal of Experimental Medicine 208, no. 10 (2011): 2141–53. http://dx.doi.org/10.1084/jem.20102392.

Full text

Abstract:

Dendritic cells (DCs) must travel through lymphatics to carry skin antigens into lymph nodes. The processes controlling their mobilization and migration have not been completely delineated. We studied how DCs in live mice respond to skin inflammation, transmigrate through lymphatic endothelium, and propagate in initial lymphatics. At steady state, dermal DCs remain sessile along blood vessels. Inflammation mobilizes them, accelerating their interstitial motility 2.5-fold. CCR7-deficient BMDCs crawl as fast as wild-type DCs but less persistently. We observed discrete depositions of CCL21 comple

APA, Harvard, Vancouver, ISO, and other styles

30

Johnson, Louise A., and David G. Jackson. "Hyaluronan and Its Receptors: Key Mediators of Immune Cell Entry and Trafficking in the Lymphatic System." Cells 10, no. 8 (2021): 2061. http://dx.doi.org/10.3390/cells10082061.

Full text

Abstract:

Entry to the afferent lymphatics marks the first committed step for immune cell migration from tissues to draining lymph nodes both for the generation of immune responses and for timely resolution of tissue inflammation. This critical process occurs primarily at specialised discontinuous junctions in initial lymphatic capillaries, directed by chemokines released from lymphatic endothelium and orchestrated by adhesion between lymphatic receptors and their immune cell ligands. Prominent amongst the latter is the large glycosaminoglycan hyaluronan (HA) that can form a bulky glycocalyx on the surf

APA, Harvard, Vancouver, ISO, and other styles

31

Lin, J. Y., X. Y. Li, P. Dong, and T. Nakashima. "Prognostic value of lymphangiogenesis in supraglottic laryngeal carcinoma." Journal of Laryngology & Otology 125, no. 9 (2011): 945–51. http://dx.doi.org/10.1017/s0022215111001514.

Full text

Abstract:

AbstractBackground:Metastasis to regional lymph nodes via lymphatic microvessels plays a key role in cancer progression, and is an important prognostic factor in many cancers. Recent evidence suggests that tumour lymphangiogenesis promotes lymphatic metastasis.Aims:To investigate whether tumour lymphatic microvessel density correlates with clinicopathological factors and serves as a prognostic indicator of supraglottic laryngeal carcinoma progression.Methods:The lymphatics of 84 supraglottic laryngeal carcinoma cases were investigated by immunohistochemical staining for podoplanin (also termed

APA, Harvard, Vancouver, ISO, and other styles

32

Olszewski, W. L., P. Jain, M. Zaleska, E. Stelmach, and E. Swoboda. "Chronic lower limb wounds evoke systemic response of the lymphatic (immune) system." Indian Journal of Plastic Surgery 45, no. 02 (2012): 255–60. http://dx.doi.org/10.4103/0970-0358.101289.

Full text

Abstract:

ABSTRACTWound healing should not be considered as a process limited only to the damaged tissues. It is always accompanied by an intensive local immune response and in advanced stages, the systemic lymphatic (immune) structure. In this review we present evidence from our own studies as well as pertinent literature on the role of skin and subcutaneous tissue lymphatics at the wound site and of transport of antigens along with collecting afferent lymphatics to the lymph nodes. We also speculate the role of lymph nodes in raising cohorts of bacterial and own tissue antigen-specific lymphocytes and

APA, Harvard, Vancouver, ISO, and other styles

33

Burnett, Alexander F., Pamela J. B. Stone, Suzanne V. Klimberg, Jennifer L. Gregory, and Juan R. Roman. "Lower Extremity Glandography (LEG): A New Concept to Identify and Enhance Lymphatic Preservation." International Journal of Gynecologic Cancer 21, no. 3 (2011): 582–86. http://dx.doi.org/10.1097/igc.0b013e31820f5d65.

Full text

Abstract:

BackgroundLower extremity edema remains a major postoperative complication after inguinal lymphadenectomy for vulvar cancer. This study documents the lymphatic drainage of the vulva versus the lymphatic drainage of the lower extremity coming through the femoral triangle.MethodsSeven patients underwent either unilateral or bilateral inguinal lymphadenectomy in conjunction with a radical vulvar resection. Preoperatively, patients had technetium-99 injected into the vulvar cancer. Isosulfan blue was injected into the medioanterior thigh 10 cm below the inguinal ligament. The femoral triangle was

APA, Harvard, Vancouver, ISO, and other styles

34

Gavrilin, P. N., E. G. Gavrilina та V. V. Evert. "Гистоархитектоника паренхимы лимфатических узлов млекопитающих с различными типами строения внутриузлового лимфатического русла". Ukrainian Journal of Ecology 7, № 3 (2017): 96–107. http://dx.doi.org/10.15421/2017_55.

Full text

Abstract:

<p>The article analyzes the features of the histoarchitectonics of the lymph nodes of the bull (Bos taurus) and the pig (Sus scrofa domestica), depending on the type of structure and localization of the intranodal lymphatic channel. We studied somatic (Limphonodi (L.) cervicales superficiales) and visceral (L. jejunales) lymph nodes of clinically healthy mature male bulls and swine (16 and 6 months old, respectively). A complex of classical histological techniques was used, as well as the method of impregnating sections of lymph nodes with silver nitrate, modified by the authors. The mai

APA, Harvard, Vancouver, ISO, and other styles

35

Lee, Min-Young, Eun-Jung Kong, and Dong-Gyu Lee. "The Findings of SPECT/CT Concerning Bypass Lymph Circulation in Lymphedema Following Breast Cancer Surgery." Healthcare 9, no. 4 (2021): 471. http://dx.doi.org/10.3390/healthcare9040471.

Full text

Abstract:

This study aimed to determine whether bypass circulation was present in lymphedema and its effect. This was a retrospective, cross-sectional study. Patients who underwent unilateral breast cancer surgery with axillary lymph node dissection were recruited and underwent single-photon emission tomography/computed tomography (SPECT/CT). SPECT/CT was performed to detect the three-dimensional locations of radio-activated lymph nodes. Patients with radioactivity in anatomical locations other than axillary lymph nodes were classified into a positive group. All patients received complete decongestive t

APA, Harvard, Vancouver, ISO, and other styles

36

Lobov, G. I., and Zh V. Nepiyushchikh. "Structure and physiology of the lymphatic vasculature." Regional blood circulation and microcirculation 19, no. 3 (2020): 5–18. http://dx.doi.org/10.24884/1682-6655-2020-19-3-5-18.

Full text

Abstract:

The lymphatic vascular system is a highly organized network of structurally and functionally connected specialized lymphatic vessels of various sizes and lymph nodes that perform metabolic and transport functions. Lymph is a blood plasma filtrate that comprises antigen-presenting cells and lymphocytes. Via lymph, excess fluid and extravasated proteins are removed from the tissues. The lymphatic system supports an extracellular fluid homeostasis that is favorable for optimal tissue functioning by removing substances that result from metabolism or cell death, as well as optimizing immunity again

APA, Harvard, Vancouver, ISO, and other styles

37

Irjala, Heikki, Eva-Liz Johansson, Reidar Grenman, Kalle Alanen, Marko Salmi, and Sirpa Jalkanen. "Mannose Receptor Is a Novel Ligand for L-Selectin and Mediates Lymphocyte Binding to Lymphatic Endothelium." Journal of Experimental Medicine 194, no. 8 (2001): 1033–42. http://dx.doi.org/10.1084/jem.194.8.1033.

Full text

Abstract:

Continuous lymphocyte recirculation between blood and lymphoid tissues forms a basis for the function of the immune system. Lymphocyte entrance from the blood into the tissues has been thoroughly characterized, but mechanisms controlling lymphocyte exit from the lymphoid tissues via efferent lymphatics have remained virtually unknown. In this work we have identified mannose receptor (MR) on human lymphatic endothelium and demonstrate its involvement in binding of lymphocytes to lymphatic vessels. We also show that the binding requires L-selectin, and L-selectin and MR form a receptor–ligand pa

APA, Harvard, Vancouver, ISO, and other styles

38

Gantsev, S. K., M. A. Tatunov, K. S. Gantsev, S. R. Kzyrgalin, and R. S. Mukhamedyarov. "MICROSURGICAL METHODS OF EX VIVO EXAMINATION OF THE LYMPHATIC SYSTEM IN BREAST CANCER PATIENTS." Siberian journal of oncology 18, no. 3 (2019): 71–77. http://dx.doi.org/10.21294/1814-4861-2019-18-3-71-77.

Full text

Abstract:

The purpose of the study was ex vivo examination of lymph node perfusion in patients with metastatic breast cancer.Material and Methods. Lymph nodes affected with metastatic breast cancer were examined. These nodes were subsequently subjected to microsurgical dissection with the isolation of the capsule, lymphatic vessels, parenchyma and stroma. All manipulations were performed after preliminary lymph node dissection using an axillary node sample, and the dissection of an isolated lymph node from this region was then performed. A total of 100 breast cancer patients underwent lymph node dissect

APA, Harvard, Vancouver, ISO, and other styles

39

Gavrilina, O. G., L. V. Perotskaya, and N. V. Alekseeva. "Morphogenesis of limph nodes in Muscovy ducks during early posnatal onthogenesis." Ukrainian Journal of Ecology 10, no. 5 (2020): 266–73. http://dx.doi.org/10.15421/2020_242.

Full text

Abstract:

The dynamics of mass and linear parameters of lymph nodes of ducks is a direct reflection of structural and functional transformations of their lymphatic parenchyma. The peculiarities of quantitative dynamics of tissue components of peripheral lymphatic organs at early stages of postnatal ontogenesis are to a great extent determined by advanced growth rates of their absolute mass against the background of sharp increase of their antigenic stimulation intensity. Parenchyma of lymph nodes of newborn ducklings is characterized by relatively low degree of differentiation and is represented by diff

APA, Harvard, Vancouver, ISO, and other styles

40

Narini, Philip P., John L. Semple, John B. Hay, Stan J. Lugowski, and Dennis Smith. "Does Silicone Gel Migrate Via Lymphatics After Subcutaneous Injection?" Canadian Journal of Plastic Surgery 2, no. 2 (1994): 67–70. http://dx.doi.org/10.1177/229255039400200205.

Full text

Abstract:

PP Narini, JL Semple, JB Hay, SJ Lugowski, D Smith. Does silicone gel migrate via lymphatics after subcutaneous injection? Can J Plast Surg 1994;2(2):67-70. Reports have documented the presence of elemental silicon, evidence of silicone elastomer, or silicone polymers (gel) in lymph nodes and other sites distant from implanted prostheses. It has been suggested that this occurs via the lymphatic system; however, the mechanism of spread or migration of silicone has not been previously studied. This study investigated the possible role of lymphatics in the migration of silicone gel. In the sheep

APA, Harvard, Vancouver, ISO, and other styles

41

Ponzone, Riccardo, Nicoletta Tomasi Cont, Furio Maggiorotto, et al. "Extensive Nodal Disease May Impair Axillary Reverse Mapping in Patients With Breast Cancer." Journal of Clinical Oncology 27, no. 33 (2009): 5547–51. http://dx.doi.org/10.1200/jco.2009.22.1846.

Full text

Abstract:

Purpose The aim of axillary reverse mapping (ARM) is to preserve arm lymphatics in patients with breast cancer who underwent surgical axillary staging. Patients and Methods From June 2007 to December 2008, 49 patients who required axillary dissection (AD) underwent ARM. One milliliter of patent blue dye was injected in the ipsilateral arm, and all blue nodes identified during AD were sent separately for pathologic examination. Main variables associated with the detection rates of blue lymphatics, the pathologic status of blue and nonblue nodes, and the complications of the procedure were analy

APA, Harvard, Vancouver, ISO, and other styles

42

Belyaev, M. A., and A. A. Zakharenko. "Individual features of blood supply and lateral metastasis of colorectal cancer." Scientific Notes of the I. P. Pavlov St. Petersburg State Medical University 22, no. 1 (2015): 25–27. http://dx.doi.org/10.24884/1607-4181-2015-22-1-25-27.

Full text

Abstract:

One of the main causes of local recurrence of rectal cancer is the regional lymphatic nodes metastasis. Existing methods of staging does not have absolute sensitivity and specificity with regard to lesion of regional lymphatic nodes in general, and of lateral group in particular. It is necessary to look for new methods of diagnosis, to identify risk factors and unfavorable prognosis of lateral metastasis in colorectal cancer, which will provide a more differentiated approach to the choice of treatment policy, indications for neoadjuvant chemoradiotherapy and/or lymphatic node dissection. The w

APA, Harvard, Vancouver, ISO, and other styles

43

Liersch, Ruediger, and Michael Detmar. "Lymphangiogenesis in development and disease." Thrombosis and Haemostasis 98, no. 08 (2007): 304–10. http://dx.doi.org/10.1160/th07-04-0238.

Full text

Abstract:

SummaryThe lymphatic vascular system plays an important role in the maintenance of fluid homeostasis, in the afferent immune response, in the intestinal lipid uptake and in the metastatic spread of malignant cells. The recent discovery of specific markers and growth factors for lymphatic endothelium and the establishment of genetic mouse models with impairment of lymphatic function have provided novel insights into the molecular control of the lymphatic system in physiology and in embryonic development. They have also identified molecular pathways whose mutational inactivation leads to human d

APA, Harvard, Vancouver, ISO, and other styles

44

Vavra, Petr, Marie Rydlova, Anton Pelikan, et al. "Tiesiosios žarnos vėžio chirurginis gydymas Ostravos universiteto ligoninėje, Čekijos Respublika." Lietuvos chirurgija 2, no. 3 (2004): 0. http://dx.doi.org/10.15388/lietchirur.2004.3.2361.

Full text

Abstract:

Petr Vavra1, Marie Rydlova3, Anton Pelikan1, Lubomir Martinek1, Petra Gunkova1, Michaela Vavrova2, Igor Gunka11 Department of Surgery and 2 Department of Radiology,University Hospital of Ostrava,3 Department of Pathology, Medical-Social Facultyof University of Ostrava,17 listopadu 1790, 708 52 Ostrava Poruba,Czech RepublicE-mail: p_vavra@quick.cz Background / objective Czech Republic is among the countries with the highest incidence of rectal cancer. The aim of the prospective study was to monitor the surgical treatment of patients with the diagnosis of rectal cancer. Patients and methods 188

APA, Harvard, Vancouver, ISO, and other styles

45

Guerrero, F., P. Cerutti, A. Marcaccini, and A. García. "Histological and Immunohistochemical Study on Iberian Red Deer (Cervus elaphus hispanicus) Haemal Nodes." Microscopy and Microanalysis 18, S5 (2012): 1–2. http://dx.doi.org/10.1017/s1431927612012664.

Full text

Abstract:

Haemal nodes are capsulated, lymphoid organs with haemal circulation. Their parenchyma is distributed in primary and secondary lymphatic nodes in the cortical and medullar zones. In these zones the lymphatic tissue may adopt a cord-like shape and it is composed by plasma cell, macrophages and B and T lymphocytes. Blood circulates through the sinuses situated underneath the capsule, around the trabeculae and in the marrow.

APA, Harvard, Vancouver, ISO, and other styles

46

Staszyk, Carsten, Katja F. Duesterdieck, Hagen Gasse, and Astrid Bienert. "Immunohistochemical Identification of Lymphatic Vessels in the Periodontium of Equine Cheek Teeth." Journal of Veterinary Dentistry 22, no. 4 (2005): 227–32. http://dx.doi.org/10.1177/089875640502200402.

Full text

Abstract:

Immunohistochemical detection of lymphatic capillaries was performed in the periodontium of maxillary and mandibular cheek teeth from 6 horses (aged 3–23 years). Tissue sections of the periodontium were taken at 4 different horizontal levels along the long axis of the tooth. The specimens were processed for immunoreaction with anti-Proxl, in order to distinguish lymphatic endothelium from blood vascular endothelium. Lymphatic vessels were detected in all periodontal tissues except for the dental cementum. Lymphatic capillaries were most densely distributed in the gingiva compared to other tiss

APA, Harvard, Vancouver, ISO, and other styles

47

Zhou, Hengbo, Pin-ji Lei, and Timothy P. Padera. "Progression of Metastasis through Lymphatic System." Cells 10, no. 3 (2021): 627. http://dx.doi.org/10.3390/cells10030627.

Full text

Abstract:

Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate. Thus, it is important to understand the mechanisms by which lymph node metastases progress and how they can be targeted to provide therapeutic benefits. In this review, we focus on delineating the process of cancer cell migration to and through lymphatic vessels, survival in draining lymph nodes and further spread to other distant organs. In addition, emerging molecular targets and potential strategies to

APA, Harvard, Vancouver, ISO, and other styles

48

Wang, Donghua, Manyu Chen, Long Lv, Yu Chen, and Kui Tian. "Injection of Carbon Nanoparticles for Lymph Node Detection After Laparoscopic Colorectal Cancer Surgery." Journal of Nanoscience and Nanotechnology 21, no. 2 (2021): 886–94. http://dx.doi.org/10.1166/jnn.2021.18667.

Full text

Abstract:

Colorectal cancer is the third most common cause of cancer-related death in the world because of its poor prognosis and many related complications. In clinical practice, lymph node metastasis is an important index to evaluate the recurrence and survival rate of patients with rectal cancer, it also the main method to determine the treatment plan of patients with rectal cancer. Nano carbon tracer can guide surgeons to clear regional lymph nodes accurately, improve the number of lymph nodes detected, and then improve the accuracy of pathological staging of rectal cancer. It has an important clini

APA, Harvard, Vancouver, ISO, and other styles

49

Gale, Nicholas W., Remko Prevo, Jorge Espinosa, et al. "Normal Lymphatic Development and Function in Mice Deficient for the Lymphatic Hyaluronan Receptor LYVE-1." Molecular and Cellular Biology 27, no. 2 (2006): 595–604. http://dx.doi.org/10.1128/mcb.01503-06.

Full text

Abstract:

ABSTRACT The hyaluronan receptor LYVE-1 is expressed abundantly on the surfaces of lymphatic vessels and lymph node sinus endothelial cells from early development, where it has been suggested to function both in cell adhesion/transmigration and as a scavenger for hyaluronan turnover. To investigate the physiological role(s) of LYVE-1, we generated mice in which the gene for the receptor was inactivated by replacement with a β-galactosidase reporter. LYVE-1−/− mice displayed an apparently normal phenotype, with no obvious alteration in lymphatic vessel ultrastructure or function and no apparent

APA, Harvard, Vancouver, ISO, and other styles

50

Nitschké, Maximilian, David Aebischer, Michael Abadier, et al. "Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation." Blood 120, no. 11 (2012): 2249–58. http://dx.doi.org/10.1182/blood-2012-03-417923.

Full text

Abstract:

Abstract Dendritic cell (DC) migration via lymphatic vessels to draining lymph nodes (dLNs) is crucial for the initiation of adaptive immunity. We imaged this process by intravital microscopy (IVM) in the ear skin of transgenic mice bearing red-fluorescent vasculature and yellow-fluorescent DCs. DCs within lymphatic capillaries were rarely transported by flow, but actively migrated within lymphatics and were significantly faster than in the interstitium. Pharmacologic blockade of the Rho-associated protein kinase (ROCK), which mediates nuclear contraction and de-adhesion from integrin ligands,

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!