Relevant bibliographies by topics / Lymphatic system

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Lymphatic system'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Lymphatic system"

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Markova, Valeriya I. "THE LYMPHATIC SYSTEM – A NEW LOOK AT OLD PROBLEMS." Morphological newsletter 30, no. 3 (July 25, 2022): 24–29. http://dx.doi.org/10.20340/mv-mn.2022.30(3).734.

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The lack of adequate methods for the simultaneous detection of lymphatic and blood microvessels in hollow organs does not make it possible to determine the morphological basis of lymph formation and lymph dynamics. In the relevant scientific literature, information about of the structural organization of the lymphatic system, obtained using transmission and scanning electron microscopy, does not provide exhaustive answers to the currently controversial and unresolved issues of the structural organization of the lymphatic microcirculatory bed. The purpose of the study is to presenting data on the organization of the initial lymphatic channel, obtained on the basis of the use of original impregnation methods. Studies were conducted on cats (n=17) and dogs (n=11). The microvascular bed of the intestine and epicardium was identified along with the surrounding tissues by impregnation. On histological preparations, endothelial trabeculae were identified in the lumen of non-muscular lymphatic microvessels of different diameters in the muscular layer and in the submucosa of the intestine. In the muscular layer of the intestinal wall, numerous interstitial channels were found that communicated with open lymphatic capillaries. In the submucosa of the intestinal wall of experimental animals, in addition to the classic capillaries that begin closedly, previously unknown structures were identified - open perivasal lymphatic microvessels and open lymphatic capillaries flowing into them. In the lumen of the perivasal lymphatics are arterioles or arteries. Lymphatic capillaries were in various functional states, which indicates their active peristalsis and suction capacity, which characterize them as utilizers of «biological debris». As a result of the conducted studies, new objective data on the structural organization of the initial lymphatic bed in hollow organs were obtained. The authors showed that the vasomotor activity of the initial lymphatics can serve as a morphological basis for the hypothesis of the initial lymphatic cycle, which consists of a resorption phase and an expulsion phase. The hydrostatic pressure drops in the lumen arising from such a two-phase vasomotor activity of the lymphatics indicate their important role in the process of lymph formation and lymph circulation.
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Kraft, Jamie D., Robert Blomgran, Iben Lundgaard, Marianne Quiding-Järbrink, Jonathan S. Bromberg, and Emma Börgeson. "Specialized Pro-Resolving Mediators and the Lymphatic System." International Journal of Molecular Sciences 22, no. 5 (March 9, 2021): 2750. http://dx.doi.org/10.3390/ijms22052750.

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Diminished lymphatic function and abnormal morphology are common in chronic inflammatory diseases. Recent studies are investigating whether it is possible to target chronic inflammation by promoting resolution of inflammation, in order to enhance lymphatic function and attenuate disease. Resolution of inflammation is an active process regulated by bioactive lipids known as specialized pro-resolving mediators (SPMs). SPMs can modulate leukocyte migration and function, alter cytokine/chemokine release, modify autophagy, among other immune-related activities. Here, we summarize the role of the lymphatics in resolution of inflammation and lymphatic impairment in chronic inflammatory diseases. Furthermore, we discuss the current literature describing the connection between SPMs and the lymphatics, and the possibility of targeting the lymphatics with innovative SPM therapy to promote resolution of inflammation and mitigate disease.
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Kondo, Reiichiro, and Yasuko Iwakiri. "The lymphatic system in alcohol-associated liver disease." Clinical and Molecular Hepatology 26, no. 4 (October 1, 2020): 633–38. http://dx.doi.org/10.3350/cmh.2020.0179.

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The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.
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Pecking, A., R. Cluzan, J. P. Desprez-Curely, and P. Guérin. "Functional Study of the Limb Lymphatic System." Phlebology: The Journal of Venous Disease 1, no. 2 (September 1986): 129–33. http://dx.doi.org/10.1177/026835558600100207.

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Radionuclide lymphoscintigraphy with rhenium sulphide colloid (RSC), average particle size 40 nm was used as a functional test of the limb lymphatic system. When injected subcutaneously in the hand or the foot all the RSC which leave the injection site enters the lymphatic system. From the disappearance time-activity curve detected over the injection site, we calculated the half-life and the lymphatic colloidal clearance (LC) of the RSC. These two parameters appeared to be closely depending on the macrophage function and on the permeability of the initial lymphatics. We also measured the necessary time for RSC to reach the knee or the elbow and calculated a lymphatic speed (LS) closely related to the lymph flow. The study was first carried out on 40 healthy volunteers and then on 221 patients with limb lymphoedemas. The reproducibility of the method was good when 4 days at least separate two functional tests ( r = 0.95 for half-life, r = 0.86 for lymphatic clearance at the injection site and r = 0.93 for lymphatic speed). In addition with the lymphatic images detected 1 h after the injection the functional study may become a useful technique to differentiate the lymphatic drainage diseases.
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Marti, Daniela, Dorina Coricovac, Iulia Pinzaru, Anca Isaia, Razvan Susan, Daniela Ionescu, Oana Suciu, Monica Susan, and Voichita Lazureanu. "Drug Delivery Systems for Lymphatic Uptake." Revista de Chimie 68, no. 12 (January 15, 2018): 2902–6. http://dx.doi.org/10.37358/rc.17.12.6003.

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The lymphatic system is considered to be the second circulatory system within the body, responsible for the maintenance of fluid homeostasis and immune protection. Among the aforementioned roles, it was proved that lymphatics are involved in dissemination of cancer and infections. This review offers a short description of the physiological features of lymphatic network, the lymphatic transport and the main drug delivery systems for lymphatic uptake.
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Scaglioni, Mario, and Hiroo Suami. "Anatomy of the Lymphatic System and the Lymphosome Concept with Reference to Lymphedema." Seminars in Plastic Surgery 32, no. 01 (February 2018): 005–11. http://dx.doi.org/10.1055/s-0038-1635118.

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AbstractPrecise knowledge of the lymphatic system normal anatomy is essential for understanding what structural changes occur in patients with lymphedema. In this article, the authors first review previous anatomical studies and summarize the general anatomy of the lymphatic system and lymphatic pathways in the upper and lower extremities. Second, they introduce their new anatomical concept, the “lymphosome,” which describes how the lymphatic vessels in a particular region connect to the same subgroup of regional lymph nodes. In addition, they describe the anatomical relationship between the perforating lymphatic vessels and arteries. In the last section, they explain the anatomical changes in the lymphatics after lymph node dissection, with reference to secondary lymphedema.
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Baldwin, Megan E., Michael M. Halford, Sally Roufail, Richard A. Williams, Margaret L. Hibbs, Dianne Grail, Hajime Kubo, Steven A. Stacker, and Marc G. Achen. "Vascular Endothelial Growth Factor D Is Dispensable for Development of the Lymphatic System." Molecular and Cellular Biology 25, no. 6 (March 15, 2005): 2441–49. http://dx.doi.org/10.1128/mcb.25.6.2441-2449.2005.

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ABSTRACT Vascular endothelial growth factor receptor 3 (Vegfr-3) is a tyrosine kinase that is expressed on the lymphatic endothelium and that signals for the growth of the lymphatic vessels (lymphangiogenesis). Vegf-d, a secreted glycoprotein, is one of two known activating ligands for Vegfr-3, the other being Vegf-c. Vegf-d stimulates lymphangiogenesis in tissues and tumors; however, its role in embryonic development was previously unknown. Here we report the generation and analysis of mutant mice deficient for Vegf-d. Vegf-d-deficient mice were healthy and fertile, had normal body mass, and displayed no pathologic changes consistent with a defect in lymphatic function. The lungs, sites of strong Vegf-d gene expression during embryogenesis in wild-type mice, were normal in Vegf-d-deficient mice with respect to tissue mass and morphology, except that the abundance of the lymphatics adjacent to bronchioles was slightly reduced. Dye uptake experiments indicated that large lymphatics under the skin were present in normal locations and were functional. Smaller dermal lymphatics were similar in number, location, and function to those in wild-type controls. The lack of a profound lymphatic phenotype in Vegf-d-deficient mice suggests that Vegf-d does not play a major role in lymphatic development or that Vegf-c or another, as-yet-unknown activating Vegfr-3 ligand can compensate for Vegf-d during development.
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Li, Claire Y., Stav Brown, Babak J. Mehrara, and Raghu P. Kataru. "Lymphatics in Tumor Progression and Immunomodulation." International Journal of Molecular Sciences 23, no. 4 (February 15, 2022): 2127. http://dx.doi.org/10.3390/ijms23042127.

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The lymphatic system consists of a unidirectional hierarchy of vessels responsible for fluid homeostasis, lipid absorption, and the transport of immune cells and antigens to secondary lymphoid organs. In cancer, lymphatics play complex and heterogenous roles that can promote or inhibit tumor growth. While lymphatic proliferation and remodeling promote tumor dissemination, functional lymphatics are necessary for generating an effective immune response. Recent reports have noted lymphatic-dependent effects on the efficacy of immunotherapy. These findings suggest that the impact of lymphatic vessels on tumor progression is organ- and context-specific and that a greater understanding of the interaction of tumor cells, lymphatics, and the tumor microenvironment can unveil novel therapies.
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Lewis, J. M., and E. R. Wald. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 76, no. 1 (July 1985): 168. http://dx.doi.org/10.1097/00006534-198507000-00085.

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Rayner, Colin R. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 79, no. 2 (February 1987): 322. http://dx.doi.org/10.1097/00006534-198702000-00094.

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Dissertations / Theses on the topic "Lymphatic system"

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Abu-Hijleh, Marwan. "Studies on the lymphatic system." Thesis, University of Glasgow, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305962.

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Harty, Helen Rosemary. "Nervous control of the sheep lymphatic system." Thesis, Queen's University Belfast, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335493.

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Christy, Nicola Margaret. "Targeting of colloids to the lymphatic system." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334516.

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Hawley, Ann Elizabeth. "The uptake of nanospheres by the lymphatic system." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307765.

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Uddin, Mohammad Nasir. "Lymphatic and glymphatic systems in the eye: relevance to ocular fluid drainage and glaucoma." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/27235.

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This thesis investigates retinal glymphatic and meningeal lymphatic systems in mammalian eyes, with an emphasis on structural characterization and glaucomatous changes in human eye. Chapter 2 investigates a glymphatic pathway in human and rat retina. Retinas from post-mortem human eyes were examined using immunohistochemistry and in ultrastructural studies. Dextrans were injected into the vitreous chamber of adult rat eyes. Retinal astrocytes and Müller cells were seen to envelop the entire retinal vasculature and express aquaporin-4 (AQP4) on their perivascular end feet. Perivascular spaces were observed around retinal arterioles and venules. The AQP4-positive astroglia and Müller glia formed a syncytial network between the blood vessels in the retinal parenchyma. Tracer studies showed the presence of a perivascular fluid outflow pathway. Chapter 3 provides the first unequivocal identification of lymphatic vessels in human optic nerve meninges. Post-mortem human optic nerve meninges were examined using immunohistochemical studies and in ultrastructural studies. Tracers were injected into suprachoroidal space of rat eyes. Results from ultrastructural studies showed characteristic features of lymphatics in human optic nerve meninges. Consistently, immunohistochemistry showed the presence of lymphatic capillaries in the meninges. Tracer studies showed lymphatic drainage into deep cervical lymph nodes via meningeal lymphatics. Chapter 4 investigates structural changes of the lymphatic and glymphatic systems in glaucomatous human eyes. Retina and optic nerve from glaucoma and non-glaucoma human eyes were examined with immunohistochemistry. The results showed activation of glial cells in retina and optic nerve. In the glaucomatous meninges, increased density of lymphatic vessels and macrophages was observed. Overall, the findings from this thesis contribute to further understanding of the lymphatic and glymphatic systems in mammalian eyes in health and disease.
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Castor, Joshua D. "The Role of GPNMB on Lymphangiogenesis." NEOMED College of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ne2gs1625058092906364.

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Boulton, Melfort R. "Quantitation of lymphatic drainage of the central nervous system in sheep." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq41406.pdf.

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Akin, Ryan E. "Minimally invasive assessment of lymphatic pumping pressure using near infrared imaging." Thesis, Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/47536.

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Although the major functions of the lymphatic system are fairly well defined, its vasculature has yet to be well characterized in comparison to its blood vasculature counterpart. Recent advances in optical imaging techniques have allowed for more detailed and quantitative evaluations of lymph flow dynamics and mechanism. A rat tail is often used for investigations of lymph flow because of the simple geometry, superficial nature, and disease progression models of its collecting lymphatic vessels. In this study, a pressure cuff system was fabricated and coupled with an existing functional near infrared (NIR) imaging system to measure the overall pumping pressure of the lymphatic vessels of a rat tail. In addition to adapting the system for use on rodents, previous systems used for measuring lymphatic pumping pressure in humans were improved upon in several ways. The system defined here utilizes closed-loop feedback control of pressure application at smaller, more precise intervals. Using this device, a significant difference in lymphatic vessel pumping pressure was detected between a control case and a treatment case in which a vasoactive substance with a nitric oxide donor (GTNO ointment) was applied to the tail. Although it is known that nitric oxide plays a crucial physiologic role in propagation of flow through lymphatic vessels, this study has quantified its significant pharmacological reduction of pumping pressure for the first time.
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Almasmoum, Hibah. "Biochemical analysis of the BTG1 variants associated with Non-Hodgkin's lymphoma." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/47720/.

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Non-Hodgkin’s lymphoma (NHL) is a group of lympho-proliferative disorders characterised by genetic mutations resulting in the selection of a malignant clone. Recently, mutations in the anti-proliferative B-cell translocation 1 gene (BTG1) and B-cell translocation 2 gene (BTG2) have been identified in in NHL cases, which suggests a direct involvement of BTG1 and BTG2 in malignant transformation. BTG1 and BTG2 are members of the human BTG/TOB family. They are characterised by the conserved amino-terminal BTG domain, which mediates interactions with the human Caf1(hCaf1) catalytic subunit of the Ccr4-Not deadenylase complex .In addition, the BTG domain binds to the cytoplasmic poly (A)-binding protein (PABPC1). This complex plays a critical role in mRNA deadenylation and degradation as well as translational repression. It is currently unclear how, or indeed whether, mutations in BTG1 and BTG2 affect the function of the gene products. Therefore, a combination of sequence analysis and molecular modelling was used to predict the functional consequences of mutations previously identified in NHL. Sorting intolerant from tolerant (SIFT) and Suspect (Disease-Susceptibility-based SAV Phenotype Prediction) prediction tools enabled the identification of amino acid residues that would potentially interfere with the protein function, and hence may be associated with disease. In total 45 mutations in BTG1 and BTG2 were assessed. These mutations were derived from NHL samples, including diffuse large B-cell lymphoma (DLBCL), follicular lymphoma and Burkitt's lymphoma. Of the variants analysed, 15 were predicted to interfere with the function of BTG1 using SIFT analysis (Score ≤0.05). Only seven of these variants were predicted to be likely associated with disease using Suspect algorithm (Score ≥50), and an additional variant, BTG1 C149del, was predicted to interfere with protein function using PROVEN (Protein Variation Effect Analyzer). The ability of these protein variants to interact with known partners was established using yeast two hybrid assays. In addition, functionally assessment of the role of the mutated proteins in cell cycle progression, translational repression and mRNA degradation was also performed. Using a yeast two-hybrid system, ten BTG1 variants were shown to affect the interaction of BTG1 with the hCaf1 (CNOT7/CNOT8) catalytic subunit of the Ccr4-Not deadenylase complex. In addition, when BTG1 variants were transfected into mammalian cells, these BTG1 variants (M11I, F25C, R27H, F40C, P58L, G66V, N73K and I115V), unlike the wild-type proteins, were not able to inhibit cell cycle progression. These results suggest that anti-proliferative BTG1 is required for hCaf1 (CNOT7/CNOT8) deadenylase activity. The remaining BTG1 variants (L37M, L94V, L104H and E117D) were not consistent in the correlation of BTG1 interaction with hCaf1 (CNOT7/CNOT8) and inhibition of cell growth which led to the suggestion that BTG1 may require an additional factor such as PABPC1. Interestingly, several BTG1 variants (M11I, F25C, R27H, P58L, N73K I115V and E117D) did not require interaction with the hCaf1 (CNOT7/CNOT8) deadenylase enzyme to reduce reporter activity as established using 3’ UTR tethering assays. This suggests that BTG1 may also have a role in regulating cell cycle progression and RNA degradation via Ccr4-Not deadenylase complex independent mechanisms. The data show that variants in BTG1 commonly found in DLBCL, are functionally significant and are likely to contribute to malignant transformation and tumour cell grow.
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Ahankari, A. S. "Maharashtra Anaemia Study : an investigation of factors associated with adolescent health and pregnancy-related outcomes in women from Maharashtra State, India." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/47078/.

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Maharashtra Anaemia study (MAS) was conducted as a part of the PhD programme of Dr Anand Ahankari through a joint collaboration of the University of Nottingham, UK and Halo Medical Foundation, India. The main goal of the study was to establish baseline epidemiological data for anaemia research in pregnant women and adolescent girls in Maharashtra state of India. Iron deficiency anaemia is the most common form of anaemia observed in India, and assessed based on haemoglobin (Hb) levels in blood. Clinically, anaemia is categorised in mild, moderate and severe form based on Hb levels. The project had three main sections, a) Adolescent girls cross sectional survey, b) Pregnant women prospective study, and c) Maharashtra state birth registry analysis. The study aimed to investigate individual and village level risk factors of anaemia in adolescent girls (13 to 17 years), and pregnant women (3 to 5 months) living in rural Maharashtra. Data from pregnant women were also used to examine risk factors associated with low birth weight (LBW). A recently introduced non-invasive haemoglobin (Hb) technology (known as NBM 200) was validated in this Indian setting by comparing Hb measurements obtained from the NBM 200 with reference blood measurements. In the adolescent survey, Sahli’s hemometer (finger prick technique) was used to estimate reference Hb values, while in pregnant women venous blood samples were obtained to measure Hb using an automated analyser. Anaemia was defined using Hb levels based on the following cut offs, (a) Hb < 12.0 g/dl in adolescent girls, and in (b) Hb < 11.0 g/dl in pregnant women. Multivariable regression technique was used to identity risk factors associated with anaemia and LBW. The Maharashtra state birth registry records covering a 32-year period (1980 to 2011) were investigated to assess temporal changes in the sex ratio at birth to investigate impacts of sex determination prevention legislations (known as PNDT 1994 and PCPNDT 2003). The adolescent girls’ survey showed a very high prevalence of anaemia (87%). Of 45 factors assessed in the survey, four were associated with adolescent anaemia. Anaemia likelihood increased significantly with age (Odds Ratio [OR] 1.41 per year, 95% CI: 1.17 to 1.70). Factors associated with decreased risk of anaemia were higher mid upper arm circumference (> 22 cm) (OR 0.51, 95% CI: 0.31 to 0.82), and ≥3 days/week consumption of fruit (OR 0.35, 95% CI: 0.23 to 0.54). At village level piped water supply was associated with higher Hb levels (β coefficient 0.61 g/dl, 95% CI: 0.39 to 0.82). Results from the NBM 200 reported wide agreement levels in the Bland-Altman analysis (mean difference of -2.70 g/dl, 95% CI: -2.84 to -2.55) demonstrating an overestimation of Hb by the NBM 200 compared to Sahli’s hemometer. The NBM 200 showed low sensitivity (23.6%) and moderate specificity (61.8%) for the diagnosis of anaemia in the adolescent population. Findings from pregnant women showed high anaemia prevalence (77%). Of 51 factors assessed in the study, three were associated with maternal anaemia. Increased risk of anaemia was seen in women with consanguineous marriages (OR 2.41, 95% CI: 1.16 to 5.01). Post-delivery data from full-term singleton live births showed the prevalence of LBW babies was 7%. Consanguineous marriage was a major risk of LBW babies in our study population (OR 5.68, 95% CI: 1.58 to 20.32). Village level risk factors showed lower likelihood of maternal anaemia with regular access to government nurses (OR 0.48, 95% CI: 0.25 to 0.93). The NBM 200 validation showed overestimation of Hb levels and underestimation of anaemia. Bland-Altman analysis showed a mean difference of -1.8 g/dl (95% CI: -2.06 to -1.71) indicating a systematic overestimation by the NBM 200 compared to venous Hb measurements. The device showed low sensitivity (33.7%) but high specificity (91.8%) for the diagnosis of anaemia in the pregnant woman population. The 32 years of longitudinal birth registry data showed a significant increase in the sex ratio at live birth from 1980 to 2004, and then a subsequent decrease in sex ratio. The annual state male:female sex ratio of Maharashtra increased from a baseline of 1.11 in 1980 to a maximum value of 1.23 in 2003, before decreasing to 1.16 in 2011. This represented an increase in the annual sex ratio at live birth from 1980 to 2004 of 0.005 units per year (p < 0.001), and a decrease of 0.009 units per year after 2004 (p < 0.01). The increase in the sex ratio was consistent with the hypothesis of both increasing availability and acceptability of ultrasound scanning during this period, enabling foeticide of females in utero. The probable cause for the decrease in sex ratio after 2004 is likely to be due to the strengthening of the legislation banning sex-specific foeticide.
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Books on the topic "Lymphatic system"

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1963-, Windelspecht Michael, ed. The lymphatic system. Westport, Conn: Greenwood Press, 2004.

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Karunamuni, Ganga, ed. The Cardiac Lymphatic System. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-6774-8.

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Gold, John Coopersmith. The circulatory and lymphatic systems. Berkeley Heights, NJ, USA: Enslow Publishers, 2004.

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K, White Elizabeth, ed. Hematology, the lymphatic system, and the immune system. 3rd ed. Englewood Cliffs, N.J: Regents/Pentice Hall, 1993.

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International, Congress of Lymphology (18th 2001 Genoa Italy). Progress in lymphology--XVIII: Proceedings of the 18th International Congress of Lymphology, September 3-7, 2001, Genoa, Italy. [S.l: s.n.], 2002.

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Santambrogio, Laura, ed. Immunology of the Lymphatic System. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-3235-7.

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Mitsumasa, Nishi, Uchino Shigeo, and Yabuki Soh, eds. Progress in lymphology--XII: Proceedings of the XIIth International Congress of Lymphology, held in Tokyo, Kyoto, Japan, 27 August - 2 September 1989. Amsterdam: Excerpta Medica, 1989.

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R, Casley-Smith J., and Piller N. B, eds. Progress in lymphology, X: Proceedings of the Xth International Congress of Lymphology, Adelaide, 1985. Adelaide: University of Adelaide, 1985.

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Gantsev, Shamil, Kamil Gantsev, and Shamil Kzyrgalin. Atlas of Lymphatic System in Cancer. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-40967-8.

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Kiefer, Friedemann, and Stefan Schulte-Merker, eds. Developmental Aspects of the Lymphatic Vascular System. Vienna: Springer Vienna, 2014. http://dx.doi.org/10.1007/978-3-7091-1646-3.

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Book chapters on the topic "Lymphatic system"

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Goel, Trilok Chandra, and Apul Goel. "Lymphatic System." In Lymphatic Filariasis, 29–49. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-2257-9_4.

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Oyen, R. H. "Lymphatic System." In Abdominal and Pelvic MRI, 167–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-18194-8_13.

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Grosse-Wilde, H., and U. W. Schaefer. "Lymphatic System." In Medical Radiology, 171–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-83416-5_5.

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Maker, Vijay K., and Edgar D. Guzman-Arrieta. "Lymphatic System." In Cognitive Pearls in General Surgery, 453–61. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1850-8_23.

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Oates, M. Elizabeth, and Vincent L. Sorrell. "Lymphatic System." In Myocardial Perfusion Imaging - Beyond the Left Ventricle, 109–11. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-25436-4_15.

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Gooch, Jan W. "Lymphatic System." In Encyclopedic Dictionary of Polymers, 905. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_14150.

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Salguero Bodes, Francisco Javier, and Francisco José Pallarés Martínez. "Lymphatic System." In Aughey and Frye’s Comparative Veterinary Histology with Clinical Correlates, 205–18. 2nd ed. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003333807-16.

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Kahl-Scholz, Martina, Christel Vockelmann, Ursula Blum, and Guido Heilsberg. "Lymphatic System." In Basic Knowledge Radiology, 339–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-66351-6_23.

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Maclellan, Reid A. "The Lymphatic System." In Lymphedema, 3–7. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14493-1_1.

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Lengelé, B. G. "The Lymphatic System." In Clinical Target Volumes in Conformal and Intensity Modulated Radiation Therapy, 1–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-06270-8_1.

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Conference papers on the topic "Lymphatic system"

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Weiler, Michael, and J. Brandon Dixon. "Characterization of Near-Infrared Functional Lymphatic Imaging in the Rat Tail Model." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14765.

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The lymphatic vasculature is present in nearly every tissue of the body to serve essential functions in fluid homeostasis, immune cell trafficking, and lipid transport, and it has been implicated in the progression of several diseases. Despite the critical roles that this system performs, very little is known about the lymphatic vasculature in comparison to the blood vasculature, which can be attributed, in part, to the difficulty associated with imaging lymphatic vessels. With the growing interest in studying lymphatics, near-infrared (NIR) imaging has emerged in the literature as a novel lymphatic imaging modality to simultaneously improve spatial resolution to visualize small initial lymphatics and increase temporal resolution to capture the dynamic lymphatic pump function responsible for fluid propulsion.
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2

Kornuta, Jeffrey A., and J. Brandon Dixon. "Isolated Lymphatic Vessel Perfusion System Design for Independently Controlling Hoop Stress and Shear Stress." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80437.

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Most tissues in the body are supported by the lymphatic system for a variety of functions, including the regulation of fluid balance, the removal of particulate matter from the interstitium, as well as the transport of fat from the intestine to the blood, among others. Lymphedema, a chronic disease characterized by an inability of the lymphatics to maintain tissue homeostasis and estimated to affect over 130 million people worldwide, can result in serious clinical problems for which there are very few beneficial cures or therapies [1]. However, despite the importance of lymphatics and the prevalence of lymphatic disease, very little is known about the particular mechanisms through which the lymphatics fulfill its primary functions.
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3

Wilson, John T., Rebecca L. Dahlin, Olga Gasheva, David C. Zawieja, and James E. Moore. "Nitric Oxide Transport in Lymphatic Vessels." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53886.

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The lymphatic system plays a vital role in maintaining proper physiological function in the body. Its removal of proteins and other particulate matter from the tissue spaces is particularly important for the body’s prevention of extracellular edema [1]. After fluid is absorbed by the initial lymphatics, it is transported to lymph nodes where filtration occurs. In addition, the lymphatic system serves as a common pathway of initial metastases to regional lymph nodes for certain types of cancers [2]. Thus, the characterization of mass transport in the lymphatic system could lead to unprecedented insight into the treatment of such pathologies.
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4

Faulkner, M. F., and J. Brandon Dixon. "Engineered Model of the Intestine Suggests Active Transport of Lipid by Lymphatics." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53903.

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The lymphatic system has long been thought of as little more than a series of passive ducts as they serve to return fluid and proteins from interstitial spaces back to the blood, provide a route for immune cell trafficking, and transport dietary lipid from the intestine to the blood. Recent evidence has revealed that the lymphatics play an active role in lipid trafficking, and alterations in this function have been correlated with the presence of lymphatic diseases (Dixon, 2010). Here we describe the use of a two-cell, tissue engineered model to explore mechanisms of lipid transport across lymphatic endothelial cells (LEC). Previously this model was demonstrated to recapitulate essential features of the intestinal-lacteal interface with in the mammalian gut (Dixon et al., 2009). With our model we demonstrate, not only that lipid transport across the lymphatics is transcellular and ATP dependent, but also, this mechanism of transport utilizes the molecular motors dynein and kinesin.
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5

Rahbar, Elaheh, James E. Moore, David C. Zawieja, Anatoliy A. Gashev, and Gerard L. Cote. "Developing Computational Flow Models for the Lymphatic Vasculature." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192924.

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The lymphatic system performs many crucial body functions to ensure normal health. The lymphatics are responsible for fluid and protein balance, gathering approximately 4 liters/day of interstitial fluid and returning it to the venous system. As this fluid is filtered, undesirable elements such as tumor cells and foreign pathogens are normally destroyed in lymph nodes. This system also plays a part in serving as the primary transport mechanism for the immune system. Lymphedema, a debilitating disease for which there is no known cure, affects a large number of cancer patients who have undergone lymphadenectomy and also trauma victims. The lymphatic system is also the major transport route for metastases of various cancers.
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Rahbar, Elaheh, Tony Akl, David C. Zawieja, Gerard L. Cote, and James E. Moore. "Effects of Edemagenic Stress on Lymph Transport in the Rat Mesentery." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53466.

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The lymphatic system transports fluid from the interstitium into the vascular network of lymphatic vessels through a series of valves, nodes and post-nodal ducts that converge into the subclavian veins. The lymphatics are intimately involved in fluid circulation, macromolecular homeostasis, lipid absorption, and immune function. All of these functions rely on the generation and regulation of lymph flow along the collecting lymphatic vessels. An imbalance between the lymphatic load and the ability to transport lymph can lead to lymphedema. Lymphedema occurs with a pathological increased in load, impaired vasculature (either anatomically or functionally deranged), or in situations where there is a relative distortion of both factors [1]. Edema has become a growing concern amongst breast cancer patients; surveys have reported up to 90% of women develop lymphedema in their arms within 3 years of nodal dissection surgery [2]. Despite these statistics, our knowledge of edema remains very basic and thus there is a lack of effective treatment.
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7

Dixon, J. Brandon. "Engineering Tools for Studying the Interplay Between Mechanics and Biology in Lymphatic Lipid Transport." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19364.

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The lymphatic vasculature extends through most tissues of the body and plays an essential role in maintaining fluid balance, immune cell trafficking, and lipid transport. Nearly all dietary lipid is transported from the intestine to the circulation via the lymphatic system in the form of triglyceride-rich lipoproteins called chylomicrons. This process can be described through two different mechanisms: 1) entry of the chylomicron into the initial lymphatic vessels of the small intestine, known as lacteals, and 2) the transport of these chylomicrons through the larger collecting lymphatics by a complex and coordinated system of individual contracting vessel units (lymphangions) and valve leaflets. We describe here a set of in vitro and in vivo tools we have developed to study the mechanisms that modulate lipid transport under these two different paradigms and show how these tools are uncovering important biological features involved in these mechanisms. Lymphatic pump function is known to be sensitive to the mechanical load on the vessel as the contractility of isolated vessels has been shown to be both shear and stretch sensitive [1], yet whether these mechanisms are important in regulating contractile function in vivo remains uncertain.
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8

Moore, James E. "Pumping Characteristics of the Lymphatic System." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13034.

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The lymphatic system is crucial for maintaining fluid and protein balance, and for immune function. It also plays an important role in the spread of cancer. Lymphedema can form when parts of the system are not functioning, such as in patients who have undergone lymph node resection as part of cancer therapy. Lymphedema is a painful, debilitating condition for which there is no cure. This research is aimed at constructing multi-scale models of lymphatic pumping function, incorporating information from the cellular to the whole organ level. Lymphatic endothelial and smooth muscle cell mechanotransduction events are incorporated into a single lymphangion pumping unit. The performance of this pumping unit is shown to exhibit behaviors observed in experiments with rat mesentery.
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9

Kornuta, Jeffrey A., Arina Korneva, and J. Brandon Dixon. "An In Vitro Model to Quantify the Effects of Fluid Shear Stress on Lymphatic Pump Function." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53692.

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Nearly all tissues are supported by the lymphatic system for a variety of functions, including the regulation of fluid balance, the removal of particulate matter from the interstitium, as well as the transport of fat from the intestine to the blood, among others. Despite these important functions, very little is known about the particular mechanisms through which the lymphatics fulfill these roles. Lymphedema, a chronic disease characterized by an inability of the lymphatics to maintain tissue homeostasis and estimated to affect over 130 million people worldwide, can result in serious clinical problems for which there are very few beneficial cures or therapies [1]. While fluid stagnation is the primary clinical manifestation of the disease, severe lymphedema is often correlated with tissue remodeling and the gross accumulation of lipid [1]. Given these symptoms, one must consider the breakdown in the lymphatic response to mechanical load (i.e. fluid balance) in order to understand the progression of the disease.
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10

Elshazly, Hanaa, Ahmed Taher Azar, Abeer El-korany, and Aboul Ella Hassanien. "Hybrid system for lymphatic diseases diagnosis." In 2013 International Conference on Advances in Computing, Communications and Informatics (ICACCI). IEEE, 2013. http://dx.doi.org/10.1109/icacci.2013.6637195.

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Reports on the topic "Lymphatic system"

1

Dellinger, Michael. Delineating the Effect a Novel Anti-VEGF-A Therapy has on the Lymphatic System of Immunocompetent Tumor-Bearing Mice. Fort Belvoir, VA: Defense Technical Information Center, February 2013. http://dx.doi.org/10.21236/ada577305.

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Piller, Neil, and Byung Boong Lee. VL-DUAL. Fondazione Vasculab, October 2023. http://dx.doi.org/10.24019/2023.vl-dual.

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