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Journal articles on the topic 'Lymphatic system'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Markova, Valeriya I. "THE LYMPHATIC SYSTEM – A NEW LOOK AT OLD PROBLEMS." Morphological newsletter 30, no. 3 (2022): 24–29. http://dx.doi.org/10.20340/mv-mn.2022.30(3).734.

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The lack of adequate methods for the simultaneous detection of lymphatic and blood microvessels in hollow organs does not make it possible to determine the morphological basis of lymph formation and lymph dynamics. In the relevant scientific literature, information about of the structural organization of the lymphatic system, obtained using transmission and scanning electron microscopy, does not provide exhaustive answers to the currently controversial and unresolved issues of the structural organization of the lymphatic microcirculatory bed. The purpose of the study is to presenting data on t

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2

Kraft, Jamie D., Robert Blomgran, Iben Lundgaard, Marianne Quiding-Järbrink, Jonathan S. Bromberg, and Emma Börgeson. "Specialized Pro-Resolving Mediators and the Lymphatic System." International Journal of Molecular Sciences 22, no. 5 (2021): 2750. http://dx.doi.org/10.3390/ijms22052750.

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Diminished lymphatic function and abnormal morphology are common in chronic inflammatory diseases. Recent studies are investigating whether it is possible to target chronic inflammation by promoting resolution of inflammation, in order to enhance lymphatic function and attenuate disease. Resolution of inflammation is an active process regulated by bioactive lipids known as specialized pro-resolving mediators (SPMs). SPMs can modulate leukocyte migration and function, alter cytokine/chemokine release, modify autophagy, among other immune-related activities. Here, we summarize the role of the ly

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3

Kondo, Reiichiro, and Yasuko Iwakiri. "The lymphatic system in alcohol-associated liver disease." Clinical and Molecular Hepatology 26, no. 4 (2020): 633–38. http://dx.doi.org/10.3350/cmh.2020.0179.

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The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.

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4

Marti, Daniela, Dorina Coricovac, Iulia Pinzaru, et al. "Drug Delivery Systems for Lymphatic Uptake." Revista de Chimie 68, no. 12 (2018): 2902–6. http://dx.doi.org/10.37358/rc.17.12.6003.

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The lymphatic system is considered to be the second circulatory system within the body, responsible for the maintenance of fluid homeostasis and immune protection. Among the aforementioned roles, it was proved that lymphatics are involved in dissemination of cancer and infections. This review offers a short description of the physiological features of lymphatic network, the lymphatic transport and the main drug delivery systems for lymphatic uptake.

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5

Pecking, A., R. Cluzan, J. P. Desprez-Curely, and P. Guérin. "Functional Study of the Limb Lymphatic System." Phlebology: The Journal of Venous Disease 1, no. 2 (1986): 129–33. http://dx.doi.org/10.1177/026835558600100207.

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Radionuclide lymphoscintigraphy with rhenium sulphide colloid (RSC), average particle size 40 nm was used as a functional test of the limb lymphatic system. When injected subcutaneously in the hand or the foot all the RSC which leave the injection site enters the lymphatic system. From the disappearance time-activity curve detected over the injection site, we calculated the half-life and the lymphatic colloidal clearance (LC) of the RSC. These two parameters appeared to be closely depending on the macrophage function and on the permeability of the initial lymphatics. We also measured the neces

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6

Scaglioni, Mario, and Hiroo Suami. "Anatomy of the Lymphatic System and the Lymphosome Concept with Reference to Lymphedema." Seminars in Plastic Surgery 32, no. 01 (2018): 005–11. http://dx.doi.org/10.1055/s-0038-1635118.

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AbstractPrecise knowledge of the lymphatic system normal anatomy is essential for understanding what structural changes occur in patients with lymphedema. In this article, the authors first review previous anatomical studies and summarize the general anatomy of the lymphatic system and lymphatic pathways in the upper and lower extremities. Second, they introduce their new anatomical concept, the “lymphosome,” which describes how the lymphatic vessels in a particular region connect to the same subgroup of regional lymph nodes. In addition, they describe the anatomical relationship between the p

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7

Baldwin, Megan E., Michael M. Halford, Sally Roufail, et al. "Vascular Endothelial Growth Factor D Is Dispensable for Development of the Lymphatic System." Molecular and Cellular Biology 25, no. 6 (2005): 2441–49. http://dx.doi.org/10.1128/mcb.25.6.2441-2449.2005.

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ABSTRACT Vascular endothelial growth factor receptor 3 (Vegfr-3) is a tyrosine kinase that is expressed on the lymphatic endothelium and that signals for the growth of the lymphatic vessels (lymphangiogenesis). Vegf-d, a secreted glycoprotein, is one of two known activating ligands for Vegfr-3, the other being Vegf-c. Vegf-d stimulates lymphangiogenesis in tissues and tumors; however, its role in embryonic development was previously unknown. Here we report the generation and analysis of mutant mice deficient for Vegf-d. Vegf-d-deficient mice were healthy and fertile, had normal body mass, and

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8

Li, Claire Y., Stav Brown, Babak J. Mehrara, and Raghu P. Kataru. "Lymphatics in Tumor Progression and Immunomodulation." International Journal of Molecular Sciences 23, no. 4 (2022): 2127. http://dx.doi.org/10.3390/ijms23042127.

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The lymphatic system consists of a unidirectional hierarchy of vessels responsible for fluid homeostasis, lipid absorption, and the transport of immune cells and antigens to secondary lymphoid organs. In cancer, lymphatics play complex and heterogenous roles that can promote or inhibit tumor growth. While lymphatic proliferation and remodeling promote tumor dissemination, functional lymphatics are necessary for generating an effective immune response. Recent reports have noted lymphatic-dependent effects on the efficacy of immunotherapy. These findings suggest that the impact of lymphatic vess

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9

Bertino, Frederic J., and Kin Fen Kevin Fung. "Advances and Techniques in Medical Imaging and Minimally Invasive Interventions for Disorders of the Central Conducting and Mesenteric Lymphatic System." Lymphatics 3, no. 1 (2025): 8. https://doi.org/10.3390/lymphatics3010008.

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The central conducting lymphatics (CCL) and mesenteric lymphatic systems are responsible for lipid absorption, fluid regulation, and protein delivery into the bloodstream. Disruptions in these systems can result in debilitating conditions such as chylothorax, plastic bronchitis, post-operative lymphocele, protein-losing enteropathy (PLE), and chylous ascites. Advances in imaging techniques, including magnetic resonance lymphangiography (MRL), computed tomography lymphangiography (CTL), and fluoroscopic lymphangiography, allow for detailed anatomic and functional evaluation of the lymphatic sys

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10

Szuba, Andrzej, and Stanley G. Rockson. "Lymphedema: Anatomy, Physiology and Pathogenesis." Vascular Medicine 2, no. 4 (1997): 321–26. http://dx.doi.org/10.1177/1358863x9700200408.

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The authors review the current understanding of lymphatic anatomy and physiology, and the pathophysiology of lymphedema. The skin lymphatic system consists of the initial lymphatics, which converge into lymphatic precollectors, collectors and lymphatic ducts; these in turn convey the lymph to the regional lymph nodes. Interstitial fluid and particles enter the initial lymphatics through interendothelial openings and by vesicular transport. Lymphatic uptake is enhanced by external compression. Lymphatic transport depends greatly on contraction of lymphangions, which generate the suction force t

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11

Jakovija, Arnolda, and Tatyana Chtanova. "Neutrophil Interactions with the Lymphatic System." Cells 10, no. 8 (2021): 2106. http://dx.doi.org/10.3390/cells10082106.

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The lymphatic system is a complex network of lymphatic vessels and lymph nodes designed to balance fluid homeostasis and facilitate host immune defence. Neutrophils are rapidly recruited to sites of inflammation to provide the first line of protection against microbial infections. The traditional view of neutrophils as short-lived cells, whose role is restricted to providing sterilizing immunity at sites of infection, is rapidly evolving to include additional functions at the interface between the innate and adaptive immune systems. Neutrophils travel via the lymphatics from the site of inflam

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12

Lewis, J. M., and E. R. Wald. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 76, no. 1 (1985): 168. http://dx.doi.org/10.1097/00006534-198507000-00085.

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13

Rayner, Colin R. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 79, no. 2 (1987): 322. http://dx.doi.org/10.1097/00006534-198702000-00094.

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14

Manstein, Carl H. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 109, no. 1 (2002): 412. http://dx.doi.org/10.1097/00006534-200201000-00091.

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15

Manstein, Carl H. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 86, no. 1 (1990): 176. http://dx.doi.org/10.1097/00006534-199007000-00078.

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16

Boo-Chai, Khoo. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 80, no. 6 (1987): 876. http://dx.doi.org/10.1097/00006534-198712000-00068.

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17

Baran, Namik K. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 91, no. 1 (1993): 204. http://dx.doi.org/10.1097/00006534-199301000-00061.

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18

Boo-Chi, Koo. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 93, no. 2 (1994): 447. http://dx.doi.org/10.1097/00006534-199402000-00067.

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19

Krupp, Serge. "LYMPHATIC SYSTEM." Plastic and Reconstructive Surgery 95, no. 6 (1995): 1140. http://dx.doi.org/10.1097/00006534-199505000-00060.

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20

Semyachkina-Glushkovskaya, Oxana, Dmitry Postnov, and Jürgen Kurths. "Blood–Brain Barrier, Lymphatic Clearance, and Recovery: Ariadne’s Thread in Labyrinths of Hypotheses." International Journal of Molecular Sciences 19, no. 12 (2018): 3818. http://dx.doi.org/10.3390/ijms19123818.

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The peripheral lymphatic system plays a crucial role in the recovery mechanisms after many pathological changes, such as infection, trauma, vascular, or metabolic diseases. The lymphatic clearance of different tissues from waste products, viruses, bacteria, and toxic proteins significantly contributes to the correspondent recovery processes. However, understanding of the cerebral lymphatic functions is a challenging problem. The exploration of mechanisms of lymphatic communication with brain fluids as well as the role of the lymphatic system in brain drainage, clearance, and recovery is still

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21

Bovay, Esther, Amélie Sabine, Borja Prat-Luri, et al. "Multiple roles of lymphatic vessels in peripheral lymph node development." Journal of Experimental Medicine 215, no. 11 (2018): 2760–77. http://dx.doi.org/10.1084/jem.20180217.

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The mammalian lymphatic system consists of strategically located lymph nodes (LNs) embedded into a lymphatic vascular network. Mechanisms underlying development of this highly organized system are not fully understood. Using high-resolution imaging, we show that lymphoid tissue inducer (LTi) cells initially transmigrate from veins at LN development sites using gaps in venous mural coverage. This process is independent of lymphatic vasculature, but lymphatic vessels are indispensable for the transport of LTi cells that egress from blood capillaries elsewhere and serve as an essential LN expansi

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22

Juneja, Pinky, Dinesh M. Tripathi, and Savneet Kaur. "Revisiting the gut-liver axis: gut lymphatic system in liver cirrhosis and portal hypertension." American Journal of Physiology-Gastrointestinal and Liver Physiology 322, no. 5 (2022): G473—G479. http://dx.doi.org/10.1152/ajpgi.00271.2021.

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The lymphatic vascular system runs parallel to the blood vascular system, comprising a network of lymphatic vessels and secondary lymphoid organs. The intestinal lymphatic capillaries (lacteals) and the associated collecting vessels in the mesentery form the gut lymphatic system. The gut lymphatic vasculature comprises the longest-studied lymphatic vessel bed and plays a significant role in the uptake and transport of dietary fat, abdominal fluid balance, and gut immunosurveillance. Gut is closely connected to liver through the portal circulation. In several experimental and clinical studies,

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23

Siggins, Matthew K., and Shiranee Sriskandan. "Bacterial Lymphatic Metastasis in Infection and Immunity." Cells 11, no. 1 (2021): 33. http://dx.doi.org/10.3390/cells11010033.

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Lymphatic vessels permeate tissues around the body, returning fluid from interstitial spaces back to the blood after passage through the lymph nodes, which are important sites for adaptive responses to all types of pathogens. Involvement of the lymphatics in the pathogenesis of bacterial infections is not well studied. Despite offering an obvious conduit for pathogen spread, the lymphatic system has long been regarded to bar the onward progression of most bacteria. There is little direct data on live virulent bacteria, instead understanding is largely inferred from studies investigating immune

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24

Leibaschoff, Gustavo, Julio Ferreira, and Jose Luis Ciucci. "Anatomic-Radiologic Comparison of the Effects of Liposculpture on the Lymphatic System of the Lower Extremities." American Journal of Cosmetic Surgery 12, no. 4 (1995): 287–92. http://dx.doi.org/10.1177/074880689501200402.

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A study of the lymphatic anatomy of the leg was performed using lymphography. Methods of visualization of the lymphatic anatomy are discussed and include radiographic visualization during surgery and direct examination of tissues after injection of vital dyes. Using these methods, the effect of liposuction on the lymphatics of the leg was studied in a single patient. Results of this preliminary study indicate that liposuction of the lower extremity does not cause disruption of the lymphatic system of the leg.

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25

Subileau, Mariela, and Daniel Vittet. "Lymphatics in Eye Fluid Homeostasis: Minor Contributors or Significant Actors?" Biology 10, no. 7 (2021): 582. http://dx.doi.org/10.3390/biology10070582.

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Lymphatic vessels exert major effects on the maintenance of interstitial fluid homeostasis, immune cell trafficking, lipid absorption, tumor progression and metastasis. Recently, novel functional roles for the lymphatic vasculature have emerged, which can be associated with pathological situations. Among them, lymphatics have been proposed to participate in eye aqueous humor drainage, with potential consequences on intraocular pressure, a main risk factor for progression of glaucoma disease. In this review, after the description of eye fluid dynamics, we provide an update on the data concernin

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Johnson, Louise A., and David G. Jackson. "Hyaluronan and Its Receptors: Key Mediators of Immune Cell Entry and Trafficking in the Lymphatic System." Cells 10, no. 8 (2021): 2061. http://dx.doi.org/10.3390/cells10082061.

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Entry to the afferent lymphatics marks the first committed step for immune cell migration from tissues to draining lymph nodes both for the generation of immune responses and for timely resolution of tissue inflammation. This critical process occurs primarily at specialised discontinuous junctions in initial lymphatic capillaries, directed by chemokines released from lymphatic endothelium and orchestrated by adhesion between lymphatic receptors and their immune cell ligands. Prominent amongst the latter is the large glycosaminoglycan hyaluronan (HA) that can form a bulky glycocalyx on the surf

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Yang, Sijun, Dingzong Guo, and Yaobaoan. "Histopathology of the lymphatic system in ascitic broilers." Veterinární Medicína 47, No. 9 (2012): 264–69. http://dx.doi.org/10.17221/5833-vetmed.

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Histomorphologic changes of the lymphatic system of the liver and thoracic duct were examined. The diameters of lymphatic segments isolated from the thoracic ducts of ascitic and normal broilers at 32 to 37 days of age were measured using an optical micrometer measurement system. e histopathological picture of the segments of lymphatic tissue showed lymphatic cysts bilaterally along the posterior vena cava. The hepatic capsule manifested edema, thickening, and cellular proliferation. Microscopic changes in lymphatic vessels of the hepatic capsule include lymph embolism, and lymphatic plasma r

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Mendoza, Ernesto, and Geert W. Schmid-Scho¨nbein. "A Model for Mechanics of Primary Lymphatic Valves." Journal of Biomechanical Engineering 125, no. 3 (2003): 407–14. http://dx.doi.org/10.1115/1.1568128.

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Recent experimental evidence indicates that lymphatics have two valve systems, a set of primary valves in the wall of the endothelial cells of initial lymphatics and a secondary valve system in the lumen of the lymphatics. While the intralymphatic secondary valves are well described, no analysis of the primary valves is available. We propose a model for primary lymphatics valves at the junctions between lymphatic endothelial cells. The model consists of two overlapping endothelial extensions at a cell junction in the initial lymphatics. One cell extension is firmly attached to the adjacent con

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Uddin, Nasir, and Matt Rutar. "Ocular Lymphatic and Glymphatic Systems: Implications for Retinal Health and Disease." International Journal of Molecular Sciences 23, no. 17 (2022): 10139. http://dx.doi.org/10.3390/ijms231710139.

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Clearance of ocular fluid and metabolic waste is a critical function of the eye in health and disease. The eye has distinct fluid outflow pathways in both the anterior and posterior segments. Although the anterior outflow pathway is well characterized, little is known about posterior outflow routes. Recent studies suggest that lymphatic and glymphatic systems play an important role in the clearance of fluid and waste products from the posterior segment of the eye. The lymphatic system is a vascular network that runs parallel to the blood circulatory system. It plays an essential role in mainte

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Leong, Stanley P., Alexander Pissas, Muriel Scarato, et al. "The lymphatic system and sentinel lymph nodes: conduit for cancer metastasis." Clinical & Experimental Metastasis 39, no. 1 (2021): 139–57. http://dx.doi.org/10.1007/s10585-021-10123-w.

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AbstractThe lymphatic system is a complicated system consisting of the lymphatic vessels and lymph nodes draining the extracellular fluid containing cellular debris, excess water and toxins to the circulatory system. The lymph nodes serve as a filter, thus, when the lymph fluid returns to the heart, it is completely sterile. In addition, the lymphatic system includes the mucosa-associated lymphoid tissue, such as tonsils, adenoids, Peyers patches in the small bowel and even the appendix. Taking advantage of the drainage system of the lymphatics, cancer cells enter the lymphatic vessels and the

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Brisse, Morgan E., and Heather D. Hickman. "Viral Infection and Dissemination Through the Lymphatic System." Microorganisms 13, no. 2 (2025): 443. https://doi.org/10.3390/microorganisms13020443.

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Many viruses induce viremia (virus in the blood) and disseminate throughout the body via the bloodstream from the initial infection site. However, viruses must often pass through the lymphatic system to reach the blood. The lymphatic system comprises a network of vessels distinct from blood vessels, along with interconnected lymph nodes (LNs). The complex network has become increasingly appreciated as a crucial host factor that contributes to both the spread and control of viral infections. Viruses can enter the lymphatics as free virions or along with migratory cells. Once virions arrive in t

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Welsh, John D., Mark L. Kahn, and Daniel T. Sweet. "Lymphovenous hemostasis and the role of platelets in regulating lymphatic flow and lymphatic vessel maturation." Blood 128, no. 9 (2016): 1169–73. http://dx.doi.org/10.1182/blood-2016-04-636415.

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Abstract Aside from the established role for platelets in regulating hemostasis and thrombosis, recent research has revealed a discrete role for platelets in the separation of the blood and lymphatic vascular systems. Platelets are activated by interaction with lymphatic endothelial cells at the lymphovenous junction, the site in the body where the lymphatic system drains into the blood vascular system, resulting in a platelet plug that, with the lymphovenous valve, prevents blood from entering the lymphatic circulation. This process, known as “lymphovenous hemostasis,” is mediated by activati

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Banerjee, Priyanka, Niyanshi Gaddam, Tej K. Pandita, and Sanjukta Chakraborty. "Cellular Senescence as a Brake or Accelerator for Oncogenic Transformation and Role in Lymphatic Metastasis." International Journal of Molecular Sciences 24, no. 3 (2023): 2877. http://dx.doi.org/10.3390/ijms24032877.

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Cellular senescence—the irreversible cell cycle arrest driven by a variety of mechanisms and, more specifically, the senescence-associated secretory phenotype (SASP)—is an important area of research in the context of different age-related diseases, such as cardiovascular disease and cancer. SASP factors play both beneficial and detrimental roles in age-related disease progression depending on the source of the SASPs, the target cells, and the microenvironment. The impact of senescence and the SASP on different cell types, the immune system, and the vascular system has been widely discussed. Ho

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Houck, Philip D., Hari Kumar Dandapantula, and Janet Mary Massey. "Lymphatics: Future Perspectives Unrealized Potential." Lymphatics 1, no. 2 (2023): 87–96. http://dx.doi.org/10.3390/lymphatics1020009.

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Proposed fundamental laws of biology and a model of health and disease underscore the importance of the lymphatic system. The lymphatics are responsible for two of the laws of biology and the fulcrum of health and disease balancing regeneration with degeneration through the immune system. It is responsible for protection from the environment and repair of senile and damaged tissue. Life is constantly bombarded by forces that increase entropy. Lymphatics provide negative entropy to maintain health. Lymphatics help maintain cellular homeostasis removing products of metabolism. Using these princi

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Bolte, Ashley C., Mariah E. Hurt, Igor Smirnov, et al. "Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis." Journal of Immunology 204, no. 1_Supplement (2020): 64.12. http://dx.doi.org/10.4049/jimmunol.204.supp.64.12.

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Abstract Traumatic brain injury (TBI) has emerged as a leading cause of death and disability. Despite being a growing medical issue, the biological factors that promote central nervous system (CNS) pathology and neurological dysfunction following TBI remain poorly characterized. Recently, the meningeal lymphatic system was identified as a critical mediator of drainage from the CNS. In comparison to other peripheral organs, our understanding of how defects in lymphatic drainage from the CNS contribute to disease is limited. It is still unknown how TBI impacts meningeal lymphatic function and wh

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Yağmurlu, Kaan, Jennifer D. Sokolowski, Musa Çırak, et al. "Anatomical Features of the Deep Cervical Lymphatic System and Intrajugular Lymphatic Vessels in Humans." Brain Sciences 10, no. 12 (2020): 953. http://dx.doi.org/10.3390/brainsci10120953.

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Background: Studies in rodents have re-kindled interest in the study of lymphatics in the central nervous system. Animal studies have demonstrated that there is a connection between the subarachnoid space and deep cervical lymph nodes (DCLNs) through dural lymphatic vessels located in the skull base and the parasagittal area. Objective: To describe the connection of the DCLNs and lymphatic tributaries with the intracranial space through the jugular foramen, and to address the anatomical features and variations of the DCLNs and associated lymphatic channels in the neck. Methods: Twelve formalin

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Liu, Xiaolei, and Guillermo Oliver. "The Lymphatic Vasculature in Cardiac Development and Ischemic Heart Disease." Circulation Research 132, no. 9 (2023): 1246–53. http://dx.doi.org/10.1161/circresaha.122.321672.

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In recent years, the lymphatic system has received increasing attention due to the fast-growing number of findings about its diverse novel functional roles in health and disease. It is well documented that the lymphatic vasculature plays major roles in the maintenance of tissue-fluid balance, the immune response, and in lipid absorption. However, recent studies have identified an additional growing number of novel and sometimes unexpected functional roles of the lymphatic vasculature in normal and pathological conditions in different organs. Among those, cardiac lymphatics have been shown to p

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McLafferty, Ella, Charles Hendry, and Alistair Farley. "The lymphatic system." Nursing Standard 27, no. 17 (2013): 37–42. http://dx.doi.org/10.7748/ns.27.17.37.s63.

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McLafferty, Ella, Charles Hendry, and Alistair Farley. "The lymphatic system." Nursing Standard 27, no. 15 (2012): 37–42. http://dx.doi.org/10.7748/ns2012.12.27.15.37.c9482.

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Kanter, Mitchel A. "The Lymphatic System." Plastic and Reconstructive Surgery 79, no. 1 (1987): 131–39. http://dx.doi.org/10.1097/00006534-198701000-00025.

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41

Casley-Smith, J. R. "The Lymphatic System." British Journal of Sports Medicine 19, no. 3 (1985): 177. http://dx.doi.org/10.1136/bjsm.19.3.177.

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42

Singh, Daljit. "Conjunctival Lymphatic System." Journal of Cataract & Refractive Surgery 29, no. 4 (2003): 632–33. http://dx.doi.org/10.1016/s0886-3350(03)00161-5.

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Moore, James E., and Christopher D. Bertram. "Lymphatic System Flows." Annual Review of Fluid Mechanics 50, no. 1 (2018): 459–82. http://dx.doi.org/10.1146/annurev-fluid-122316-045259.

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Wu, Theresa F., Colin J. Carati, Wallace K. MacNaughton, and Pierre-Yves von der Weid. "Contractile activity of lymphatic vessels is altered in the TNBS model of guinea pig ileitis." American Journal of Physiology-Gastrointestinal and Liver Physiology 291, no. 4 (2006): G566—G574. http://dx.doi.org/10.1152/ajpgi.00058.2006.

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The ability of the lymphatic system to actively remove fluid from the interstitium is critical to the resolution of edema. The response of the lymphatics to inflammatory situations is poorly studied, so we examined mesenteric lymphatic contractile activity in the 2,4,6-trinitrobenzenesulfonic acid (TNBS) model of guinea pig ileitis, a well-accepted animal model of intestinal inflammation, by videomicroscopy in vivo and in vitro 1, 3, and 6 days after induction of ileitis. Lymphatic function (diameter, constriction frequency, amplitude of constrictions, and calculated stroke volume and lymph fl

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Guttilla, Andrea, Paolo Beltrami, Laura Bettin, et al. "Chyluria: The State of the Art." Urologia Journal 84, no. 2 (2017): 65–70. http://dx.doi.org/10.5301/uj.5000225.

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Chyluria is the passage of chyle in the urine. The cause seems to be the rupture of retroperitoneal lymphatics into the pyelocaliceal system, giving urine a milky appearance. This communication is caused by the obstruction of lymphatic drainage proximal to intestinal lacteals, resulting in dilatation of distal lymphatics and the eventual rupture of lymphatic vessels into the urinary collecting system. This condition, if left untreated, leads to significant morbidity because of hematochyluria, recurrent renal colic, nutritional problems due to protein losses and immunosuppression resulting from

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Drake, R. E., Z. Anwar, S. Kee, and J. C. Gabel. "Intestinal lymphatic pressure increases during intravenous infusions in awake sheep." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 265, no. 3 (1993): R703—R705. http://dx.doi.org/10.1152/ajpregu.1993.265.3.r703.

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Intravenous fluid infusions cause increased venous pressure and increased lymph flow throughout the body. Together the increased lymph flow and increased venous pressure (the outflow pressure to the lymphatic system) should increase the pressure within the postnodal intestinal lymphatics. To test this, we measured the pressure in postnodal intestinal lymphatics and the neck vein pressure in five awake sheep. At baseline, the neck vein pressure was 1.2 +/- 1.5 (SD) cmH2O and the lymphatic pressure was 12.5 +/- 1.7 cmH2O. When we infused Ringer solution intravenously (10% body weight in approxim

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Attoof, Wafaa, Raja Abbas, Dunia AL-Fayad, and Sajid Hameed. "Oral Complications associated with Chemotherapy in Children's with Lymphoma." Journal of Al-Rafidain University College For Sciences ( Print ISSN: 1681-6870 ,Online ISSN: 2790-2293 ), no. 2 (October 17, 2021): 293–308. http://dx.doi.org/10.55562/jrucs.v32i2.342.

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Lymphoma is general term for a group of blood cancers that start in lymphatic system, which includes circulating lymphocytes, lymph nodes (also called lymphatic gland), spleen, tonsils, adenoids, payer patches, thymus, and bone marrow, as well as the channels (called lymphatic's or lymph vessels) that connect them, also which is a part of body's immune system and helps filter out bacteria, viruses, and the other unwanted substance.

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Goswami, Abhishek K., Minhaj S. Khaja, Trevor Downing, Nima Kokabi, Wael E. Saad, and Bill S. Majdalany. "Lymphatic Anatomy and Physiology." Seminars in Interventional Radiology 37, no. 03 (2020): 227–36. http://dx.doi.org/10.1055/s-0040-1713440.

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AbstractLymphatics have long been overshadowed by the remainder of the circulatory system. Historically, lymphatics were difficult to study because of their small and indistinct vessels, colorless fluid contents, and limited effective interventions. However, the past several decades have brought increased funding, advanced imaging technologies, and novel interventional techniques to the field. Understanding the history of lymphatic anatomy and physiology is vital to further realize the role lymphatics play in most major disease pathologies and innovate interventional solutions for them.

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Brown, H. M., R. L. Robker, and D. L. Russell. "256. Ovarian lymphatic vascular development is hormonally regulated and Adamts1-dependent." Reproduction, Fertility and Development 20, no. 9 (2008): 56. http://dx.doi.org/10.1071/srb08abs256.

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The lymphatic system is important for return of extra-vascular fluid to the blood circulation, conductance of hormones and immune cell trafficking. Delicate hormonal control of fluid conductance during reproductive cycles is exemplified by the ovarian hyperstimulation syndrome, a dangerous condition of hypovolemia caused by fluid accumulation in the abdomen and reproductive tissues, in response to hormonal hyperstimulation. This study is the first to investigate the relationship between ovarian lymphatic development and follicle growth. Quantitative morphometric analysis of vessel size and num

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Aldrich, Melissa B., John C. Rasmussen, Caroline E. Fife, Simona F. Shaitelman, and Eva M. Sevick-Muraca. "The Development and Treatment of Lymphatic Dysfunction in Cancer Patients and Survivors." Cancers 12, no. 8 (2020): 2280. http://dx.doi.org/10.3390/cancers12082280.

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Breast-cancer-acquired lymphedema is routinely diagnosed from the appearance of irreversible swelling that occurs as a result of lymphatic dysfunction. Yet in head and neck cancer survivors, lymphatic dysfunction may not always result in clinically overt swelling, but instead contribute to debilitating functional outcomes. In this review, we describe how cancer metastasis, lymph node dissection, and radiation therapy alter lymphatic function, as visualized by near-infrared fluorescence lymphatic imaging. Using custom gallium arsenide (GaAs)-intensified systems capable of detecting trace amount

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