Relevant bibliographies by topics / Lyophilization, acellular dermal matrices, wound healing

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Lyophilization, acellular dermal matrices, wound healing'

Author: Grafiati
Published: 14 March 2023
Last updated: 31 July 2025

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Journal articles on the topic "Lyophilization, acellular dermal matrices, wound healing"

1

Adegboye, Oluwatobi, Kamlen Pillay, and Saleigh Adams. "Acellular Dermal Matrices in Reconstructive Pediatric Complex Lower Limb Trauma: An Observational Study." Journal of Trauma Nursing 32, no. 1 (2025): 23–29. https://doi.org/10.1097/jtn.0000000000000829.

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BACKGROUND: Contemporary research has shown that acellular dermal matrices can benefit adult lower extremity traumatic injuries; however, its use in children has not been explored. OBJECTIVE: This study aims to explore the use of acellular dermal matrices in pediatric complex lower extremity trauma. METHODS: This single-center retrospective observational cohort study of children with complex lower extremity trauma treated with Pelnac™, commercial acellular dermal matrices, was conducted at a tertiary hospital in South Africa from 2010 to 2017. Demographic and clinical data were collected from
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Petrie, Kyla, Cameron T. Cox, Benjamin C. Becker, and Brendan J. MacKay. "Clinical applications of acellular dermal matrices: A review." Scars, Burns & Healing 8 (January 2022): 205951312110383. http://dx.doi.org/10.1177/20595131211038313.

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Introduction The extracellular matrix (ECM) plays an integral role in wound healing. It provides both structure and growth factors that allow for the organised cell proliferation. Large or complex tissue defects may compromise host ECM, creating an environment that is unfavourable for the recovery of anatomical function and appearance. Acellular dermal matrices (ADMs) have been developed from a variety of sources, including human (HADM), porcine (PADM) and bovine (BADM), with multiple different processing protocols. The objective of this report is to provide an overview of current literature a
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Williams, Tokoya, Stuti Garg, Keenan Fine, et al. "The Use of Acellular Products in Venous Leg Ulcers: A Narrative Review." Wounds: a compendium of clinical research and practice 36, no. 7 (2024): 234–44. http://dx.doi.org/10.25270/wnds/23107.

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Background. Venous leg ulcers (VLUs) are the most common type of chronic wound in the lower extremity and are often associated with redness, swelling, and pain at the site of the wound. The primary focus of VLU treatment is the promotion of wound healing through compression therapy, wound debridement, and elevation of the affected limb. Acellular matrices have gained traction as a potential adjunct to wound healing in diabetic foot ulcers. However, the clinical effect of acellular products in the setting of VLUs has not been well reported. Objective. To review the published evidence on the use
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Nam, Ha Jong, Dong Gyu Kim, Je Yeon Byeon, et al. "Advanced Secondary Intention Healing for Complex Soft-Tissue Defects Using Reprocessed Micronized Acellular Dermal Matrix." Life 14, no. 11 (2024): 1479. http://dx.doi.org/10.3390/life14111479.

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Secondary intention healing offers an alternative when surgical options are infeasible. This study analyzed the effect of micronized acellular dermal matrices (mADMs; CGderm Matrix®, CG Bio, Seoul, Republic of Korea) on secondary intention healing in patients with complex soft-tissue defects and assessed mADMs’ efficacy in promoting secondary healing and improving clinical outcomes in these challenging cases. This retrospective study included 26 patients treated with sheet-type reprocessed mADMs between August 2022 and December 2022 at Soonchunhyang University Cheonan Hospital. Patients with f
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Kankam, HKN, GJM Hourston, P. Forouhi, M. Di Candia, GC Wishart, and CM Malata. "Combination of acellular dermal matrix with a de-epithelialised dermal flap during skin-reducing mastectomy and immediate breast reconstruction." Annals of The Royal College of Surgeons of England 100, no. 8 (2018): e197-e202. http://dx.doi.org/10.1308/rcsann.2018.0127.

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IntroductionPatients with large ptotic breasts undergoing immediate implant-based reconstruction often require skin-reducing mastectomy to optimise the aesthetic outcome. However, healing complications, especially at the resulting inverted T-junction, leading to wound dehiscence, infection, skin necrosis, implant exposure and failed reconstruction have been widely reported. We present an innovative approach for immediate implant-based reconstruction combining porcine- or bovine-derived acellular dermal matrices with a de-epithelialised dermal sling to protect and support the implant, while imp
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Paganelli, A., E. Rossi, A. Naselli, P. Azzoni, L. Bertoni, and C. Magnoni. "618 Acellular Dermal Matrices in Cutaneous Wound Healing: a Longitudinal Comparative Study." Journal of Investigative Dermatology 142, no. 12 (2022): S287. http://dx.doi.org/10.1016/j.jid.2022.09.635.

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Antoinette Nguyen, Anh-Tho, and Derek Bell. "833 Cost-Effectiveness and Outcomes of Fish- vs. Human-Derived Dermal Matrices in Burn Care." Journal of Burn Care & Research 46, Supplement_1 (2025): S279. https://doi.org/10.1093/jbcr/iraf019.364.

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Abstract Introduction Acellular dermal matrices (ADM) are widely used in burn care to enhance wound healing while minimizing the need for repeated surgical interventions. This study compares the clinical outcomes and cost-effectiveness of a fish-derived acellular dermal matrix and a human-derived dermal matrix in burn patients, focusing on surgical efficiency, time to wound closure, complication rates, and hospital length of stay. Methods A retrospective cohort study was conducted at an American Burn Association (ABA) verified burn center on 156 burn patients, 18 treated with a fish-derived ma
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Nguyen, Anh-Tho Antoinette, and Derek Bell. "835 Efficacy of Fish-Derived Acellular Dermal Matrix vs. Standard Care for Symmetric Venous Stasis Ulcers." Journal of Burn Care & Research 46, Supplement_1 (2025): S280—S281. https://doi.org/10.1093/jbcr/iraf019.366.

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Abstract Introduction Chronic venous stasis ulcers are complex and challenging to manage, often resulting in prolonged healing and poor outcomes with standard wound care. This case report presents a 66-year-old female with a medical history of pyoderma gangrenosum, hypothyroidism, mitral valve prolapse, ulcerative colitis, and chronic venous insufficiency, who developed symmetric venous stasis ulcers on both lower extremities. The patient had a long-standing ulcer on the left leg (15 years) and a newer ulcer on the right leg (4 years). After multiple unsuccessful treatment modalities, the pati
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Kumar, Vineet, Naveen Kumar, Anil K. Gangwar, and Rajendra Singh. "Comparative evaluation of two different xenogenic acellular matrices on full-thickness skin wound healing." Journal of Wound Care 33, Sup3a (2024): lxxiv—lxxx. http://dx.doi.org/10.12968/jowc.2024.33.sup3a.lxxiv.

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Objective: The purpose of the study was to compare the healing potential of bubaline small intestinal matrix (bSIM) and fish swim bladder matrix (FSBM) on full-thickness skin wounds in rabbits. Method: Four full-thickness skin wounds (each 20×20mm) were created on the dorsum of 18 rabbits that were divided into three groups based on treatment: untreated sham control (I), implanted with double layers of bSIM (II) and implanted with double layers of FSBM (III). Macroscopic, immunologic and histologic observations were made to evaluate wound healing. Results: Gross healing progression in the bSIM
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Lin, Zhikai, Cristina Nica, Anton Sculean, and Maria B. Asparuhova. "Enhanced Wound Healing Potential of Primary Human Oral Fibroblasts and Periodontal Ligament Cells Cultured on Four Different Porcine-Derived Collagen Matrices." Materials 13, no. 17 (2020): 3819. http://dx.doi.org/10.3390/ma13173819.

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Xenogenic collagen-based matrices represent an alternative to subepithelial palatal connective tissue autografts in periodontal and peri-implant soft tissue reconstructions. In the present study, we aimed to investigate the migratory, adhesive, proliferative, and wound-healing potential of primary human oral fibroblasts (hOF) and periodontal ligament cells (hPDL) in response to four commercially available collagen matrices. Non-crosslinked collagen matrix (NCM), crosslinked collagen matrix (CCM), dried acellular dermal matrix (DADM), and hydrated acellular dermal matrix (HADM) were all able to
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Dissertations / Theses on the topic "Lyophilization, acellular dermal matrices, wound healing"

1

Tognetti, Linda. "Development of new acellular lyophilized dermal matrices for advanced wound healing." Doctoral thesis, Università di Siena, 2020. http://hdl.handle.net/11365/1116557.

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Though a great variety of dermal matrices and skin equivalents are available, either synthetic and semisynthetic, viable human skin allografts are still considered the most physiological alternative to autologous skin in hard-to-heal wounds. Wound closure after post-traumatic injuries and/or localized at peculiar body sites (head-and-neck, oral cavity, lower legs) are particularly challenging and can often be delayed due to local and systemic factors. In these cases, integrated medical-surgical approach based on the use of dermal acellular matrices should be considered. Skin bank are tissue es
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Nair, Rekha. "Acellular matrices derived from differentiating embryonic stem cells." Diss., Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/37170.

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Embryonic stem cells (ESCs) can differentiate into all somatic cells, and as such, are a promising cell source for therapeutic applications. In vitro, ESCs spontaneously differentiate via the aggregation of cells into embryoid bodies (EBs), which recapitulate aspects of early embryogenesis and harbor a unique reservoir of cues critical for tissue formation and morphogenesis. Embryonic healing responses employ similar intrinsic machinery used for tissue development, and these morphogenic cues may be captured within the EB microenvironment. Recent studies have shown that when injected into in
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