Relevant bibliographies by topics / Lyophilized powder for injection

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Academic literature on the topic 'Lyophilized powder for injection'

Author: Grafiati
Published: 4 June 2025
Last updated: 6 July 2025

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Journal articles on the topic "Lyophilized powder for injection"

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Blazheyevskіy, Mykola Ye, Nataliia Yu Bondarenko, and Olena O. Mozgova. "The quantitative determination of glutathione by the effect of the chemiluminescence inhibition in the catalytic oxidation reaction of luminol with hydrogen peroxide in the presence of hemoglobin." Journal of Organic and Pharmaceutical Chemistry 20, no. 1(77) (2022): 51–56. http://dx.doi.org/10.24959/ophcj.22.255967.

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Aim. To develop a method for the quantitative determination of reduced glutathione in a lyophilized powder for the preparation of “Hepaval®” solution for intravenous and intramuscular administration by the effect of inhibiting chemiluminescence in the luminol (H2L)–Н2О2–hemoglobin (Hb) system.Materials and methods. The study object was the reduced glutathione substance and lyophilized powder for the preparation of “Hepaval®” solution for injection, ampoules of 4 mL No. 10 manufactured by “Valartin pharma” (Italy). The glutathione content in powder was determined using the chemiluminescence method by the effect of inhibiting the luminol oxidation reaction with hydrogen peroxide in the presence of Hb as a catalyst. The analysis was performed by the standard addition method.Results and discussion. As a result of the studies, it has been found that under optimal conditions glutathione shows a noticeable inhibitory effect on chemiluminescence in the H2L–H2O2–Hb system. This phenomenon was used to develop a new procedure for the quantitative determination of glutathione in the substance and lyophilized powder for the preparation of “Hepaval®” aqueous solution for injection. The linear dependence of the integral chemiluminescence intencity (S) on the molar concentration of glutathione was maintained in the concentration range of (2 – 20) × 10–7 mol L-1. The graph equation was S = (–1.6 ± 0.2) × 107 × c + (198.9 ± 2.0), (r = 0.999). The relative standard deviation (RSD) was ±1.82 % (n = 7, P = 0.95). Conclusions. The method has been developed, and the possibility of the quantitative determination of glutathione in powder for the preparation of “Hepaval®” solution for injection by the method of the chemiluminescence inhibition of the H2L–Н2О2–Нb system has been shown. The content of glutathione in powder calculated with reference to dried substance was 91.49 % (against 90.8 % by the certificate). The accuracy was +0.76 %.
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Xing, Zhi Hua. "Preparation of Folate-Decorated Hydroxycamptothecin Nanoparticle Lyophilized Powder and its Antitumor Activity on Mice Bearing S180." Advanced Materials Research 905 (April 2014): 28–31. http://dx.doi.org/10.4028/www.scientific.net/amr.905.28.

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Nanoparticle lyophilized powder of HCPT/CTS-TPP-FA was prepared with hydroxycamptothecin (HCPT) as model drug, folate (FA) as targetting ligand, chitosan (CTS) as carrier, sodium tripolyphosphate (TPP) as polyanion and mannitol as cryoprotectant. The antitumor activity of HCPT/CTS-TPP-FA on mice bearing S180 was investigated. The results indicated that the lyophilized powder dispersed quickly into homogeneous emulsion colloid without any suspended substance in distilled water, glucose injection and normal saline. HCPT/CTS-TPP-FA and HCPT/CTS-TPP could both inhibit the growth of S180 tumor cells of mice, and the difference is significant (P<0.01).The inhibition rate of HCPT/CTS-TPP-FA(52.91%) is better than that of HCPT/CTS-TPP(40.06%).
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Satyanarayana, Dr L., and Dr Sumalatha Reddi. "Development and application of Liquid Chromatographic method for determination of Caspofungin Acetate in sterile, lyophilized powder for Injection." International Journal of Trend in Scientific Research and Development Volume-2, Issue-3 (2018): 455–64. http://dx.doi.org/10.31142/ijtsrd10927.

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Bukkawar, Amit R., Amit K. Jain, and Vivekanand K. Chatap. "Development and Evaluation of Vasoactive Intestinal Peptide Freeze-Dried Injection." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, no. 02 (2022): 597–604. http://dx.doi.org/10.25258/ijddt.13.2.21.

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Introduction: Vasoactive intestinal peptide (VIP), a ubiquitous, naturally synthesized human peptide is extensively documented to have diverse physiological effects like anti-inflammatory, immune-modulatory, anti-hypertensive, stimulation of contractility in the heart, vasodilation, and promoting neuroendocrine-immune communication. The synthetic form of VIP is called aviptadil (AVP). The main objective of this research was to develop a novel stable lyophilized dosage of VIP (Aviptadil) using sucrose as a bulking agent. AVP is a peptide with known concern for aqueous stability, which seems to be challenging for storing finished drug products and supply chain management. The VIP injection was developed using the lyophilization technique in the presence of bulking agent and some other pH-adjusting agent. The bulking agent and solvent system selection depends upon the solubility, stability of the drug substance, and feasibility during manufacturing. During product formulation development, the bulk solution was evaluated for processing time and temperature impact. The lyophilization cycle was developed using the most advanced freeze-drying technology. Result and discussion: With the usage of bulking agent (sucrose) as may act as a cryoprotectant for peptide, the formulated bulk solution was freeze-dried, and primary drying was done at-25°C (below than critical product temperature) followed by secondary drying at 25°C. The critical quality attributes of lyophilized drug products like the description of lyophilized cake/powder, moisture content, reconstitution time, active drug content and color of the solution were evaluated. The developed formulation bulk solution was stable and compatible with contact materials like SS vessels when hold up to 24 hours at 2 to 8°C. The optimized freeze-dried product meets the predefined acceptance criteria as part of the quality target product profile. Conclusions: It can be concluded from the research work carried out that a stable lyophilized parenteral formulation containing VIP (AVP) was developed using sucrose as a bulking agent. These findings show that the freeze-dried formulation is an appropriate technological remedy for stabilizing VIP in lyophilized injectable dosage form.
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Liu, Jing, Jianfeng Zhao, Zhong Dai, Ruichao Lin, Gangli Wang, and Shuangcheng Ma. "A Pair of New Antioxidant Phenolic Acid Stereoisomers Isolated from Danshen Injection (Lyophilized Powder)." Molecules 19, no. 2 (2014): 1786–94. http://dx.doi.org/10.3390/molecules19021786.

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Liu, Daichun, Federico Galvanin, and Ying Yu. "Formulation Screening and Freeze-Drying Process Optimization of Ginkgolide B Lyophilized Powder for Injection." AAPS PharmSciTech 19, no. 2 (2017): 541–50. http://dx.doi.org/10.1208/s12249-017-0858-2.

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Rugani, Karen de Souza, and Hérida Regina Nunes Salgado. "Stability-indicating LC method for the determination of cephalothin in lyophilized powder for injection." Anal. Methods 6, no. 12 (2014): 4437–45. http://dx.doi.org/10.1039/c3ay42049c.

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A stability-indicating gradient reversed phase liquid chromatography (RP-LC) method has been developed for the quantitative determination of cephalothin (CET), an antimicrobial compound, in the presence of its impurities and degradation products generated from forced degradation studies.
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Dr., L. Satyanarayana, and Sumalatha Reddi Dr. "Development and application of Liquid Chromatographic method for determination of Caspofungin Acetate in sterile, lyophilized powder for Injection." International Journal of Trend in Scientific Research and Development 2, no. 3 (2018): 455–64. https://doi.org/10.31142/ijtsrd10927.

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Caspofungin is an antifungal agent of the novel echinocandin class. Caspofungin, the first inhibitor of fungal b 1,3 glucan synthesis to receive approval by the United States Food and Drug Administration, is effective for the treatment of mucosal and invasive candidiasis and invasive aspergillosis. It is also active in vitro and in animal models against a number of other filamentous and dimorphic endemic fungi and in animal models of Pneumocystis carinii infection. Caspofungin is a water soluble amphipathic lipopeptide is a semisynthetic derivative of pneumocandin B0, a fermentation product of Glarea lozoyensis. Developing a accurate and precise alytical method for the estimation of cagpsofungin in a sterile, lyophilized product for intravenous IV infusion a is very challenging, due to the formation of drug drug and drug excipient interactions. The present study demonstrates the applicability of chromatographic method to develop a new, sensitive, single HPLC method for the quantitative determination of antifungal agents in freeze dried powder for injection pharmaceutical dosage form. Chromatographic separation active pharmaceutical ingredient was achieved by using a isocratic elution at a flow rate of 1.0 mL min on X Terra RP 18 column 250mm×4.6 mm, 5µm particle size, 100Ã… pore size at ambient temperature. The contents of the mobile phase were 3.48 gms of Di Potassium hydrogen ortho phosphate 0.03M in 1000 ml of water and by adjusting the pH to 3.2 with dilute ortho phosphoric acid mobile phase solvent A and acetonitrile mobile phase solvent B in a isocratic mode in the ratio of 30 70 v v of separation was used to resolute the Caspofungin. UV detection at 278 nm was employed to monitor the analytes. A linear response was observed for caspofungin over the concentration range 0.5-6 µg mL. Limit of detection LOD and Limit of quantification LOQ for Capsofungin were found to be 0.001µg mL, and 0.003µg mL respectively. Dr. L. Satyanarayana | Dr. Sumalatha Reddi "Development and application of Liquid Chromatographic method for determination of Caspofungin Acetate in sterile, lyophilized powder for Injection" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-3 , April 2018, URL: https://www.ijtsrd.com/papers/ijtsrd10927.pdf
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Tsai, Wen-Chin, Terry L. Wilke, and Praveen Tyle. "Development and validation of an HPLC method for AG331 bulk drug substance and lyophilized powder for injection." Journal of Pharmaceutical and Biomedical Analysis 35, no. 4 (2004): 697–702. http://dx.doi.org/10.1016/j.jpba.2004.01.029.

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de Aléssio, Patrícia Vidal, Ana Carolina Kogawa, and Hérida Regina Nunes Salgado. "Quality of Ceftriaxone Sodium in Lyophilized Powder for Injection Evaluated by Clean, Fast, and Efficient Spectrophotometric Method." Journal of Analytical Methods in Chemistry 2017 (2017): 1–4. http://dx.doi.org/10.1155/2017/7530242.

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Ceftriaxone sodium, an antimicrobial agent that plays an important role in clinical practice, is successfully used to treat infections caused by most Gram-positive and Gram-negative organisms. Since there are few rapid analytical methods for ceftriaxone analysis to use in the pharmaceutical routine, the aim of this research was to develop a new method able to quantify this cephalosporin. Therefore, a sensitive, rapid, simple UV spectrophotometric method for the determination and quantification of ceftriaxone sodium was proposed. The UV detector was set at 241 nm. Beer’s law obeyed the concentration range of 10–20 µg mL−1. Statistical comparison of the results with a well-established reported method showed excellent agreement and proved that there is no significant difference in the accuracy and precision. Intra- and interday variability for the method were less than 2% relative standard deviation. The proposed method was applied to the determination of the examined drugs in pharmaceutical formulations and the results demonstrated that the method is equally accurate, precise, and reproducible as the official methods.
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Dissertations / Theses on the topic "Lyophilized powder for injection"

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Гончарук, Алла Юріївна. "Обґрунтування складу і технології виробництва ліофілізованого порошку для отримання парентерального лікарського засобу". Магістерська робота, Київський національний університет технологій та дизайну, 2021. https://er.knutd.edu.ua/handle/123456789/19421.

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Дипломну магістерську роботу присвячено розробці та дослідженню композиції парентерального препарату у формі ліофілізованого порошку на основі доксицикліну хіклату. В процесі досліджень було підібрано оптимальний склад допоміжних речовин, що виконують функції антиоксидантів та стабілізаторів розчину, схильного до зміни рН в процесі зберігання. Запропоновано технологію виготовлення з використанням прийому висвітлення сорбентом, обладнання, первинну упаковку, технологічну схему, валідаційний майстер-план та діаграму Ішикави для аналізу ризиків процесу виробництва. Проведені дослідження in vitro ліофілізату та твердих желатинових капсул підтверджують еквівалентність їх бактеріостатичної дії щодо збудників бактеріальних інфекцій. На основі контролю in vivo аномальної токсичності доведено відсутність побічних реакцій протягом 72 годин після введення.<br>Master's thesis is devoted to development and research of composition of parenteral drug in form of lyophilized powder based on doxycycline hyclate. During the studies, the optimal composition of the excipients, acting as antioxidants and stabilisers for a solution prone to pH changes during storage, was selected. A manufacturing technology with the use of technique of solution clarification with sorbent is offered. Еquipment, primary packaging, flow chart, validation master plan and Ishikawa diagram for risk analysis of the manufacturing process was proposed. In vitro studies of lyophilizate and solid gelatin capsules confirm the equivalence of their bacteriostatic action against pathogens of bacterial infections. Based on in vivo control of abnormal toxicity, the absence of adverse reactions within 72 h after administration has been proved.
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Hanson, S. M. J. "Powder co-injection moulding." Thesis, Cranfield University, 2000. http://dspace.lib.cranfield.ac.uk/handle/1826/3681.

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A novel powder processing technique has been developed by combining conventional powder injection moulding with polymer co-injection moulding, to permit the in-situ surface engineering of metal or ceramic components as an integral step within the processing cycle. The new technique has been used to produce surface engineered iron based components with either corrosion resistant or wear resistant surfaces, and to produce alumina based components with toughened surfaces. The most critical factor for the feasibility of surface engineered components is that the sintering profiles of the skin and core materials must be well matched or differential shrinkage or delamination will result. A particular requirement of surface engineering is the ability to control the surface engineered skin profile. Polymer injection moulding modelling software was applied to predict the surface engineered skin profiles of the surface engineered metal/ceramic components. Successful skin profile prediction is dependent on the characterisation of the feedstock materials being injection moulded. Several feedstocks have been characterised for their material properties and first pass models developed to predict the feedstock material properties as a function of their individual material properties and mass or volume ratios. It has been demonstrated that the design of the feedstock composition and injection moulding process conditions can be optimised by the use of computer-based injection moulding modelling software to achieve the desired surface engineered skin profile. A methodology has been developed that outlines all the stages necessary for successful powder co-injection moulding.
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Wrighton, Smith Peter. "Delivery of particles by powder injection." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393515.

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De, Focatiis Davide. "Inverting domes for needle-less powder injection." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403711.

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Lane, Peter D. "Powder injection moulding of steel-hardmetal graded structure composites." Thesis, Loughborough University, 1991. https://dspace.lboro.ac.uk/2134/27790.

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Hidalgo, Garcia Javier. "Development of binder systems based on CAB for powder injection moulding (PIM) and micro powder injection moulding (µ-PIM) of Zircon and Invar powders." Thesis, Besançon, 2014. http://www.theses.fr/2014BESA2043/document.

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Les contributions de cette thèse de doctorat sont focalisées sur les développements de formulations à base de polymères bio sourcés et déliantable à l’eau basés sur l’emploi d’acétate butyrate de cellulose (CAB) et de polyéthylène glycol (PEG). Ces nouvelles formulations ont été appliquées sur différentes nuances de poudres métalliques (invar) et céramiques (zircones). Ces matériaux possèdent une bonne stabilité dimensionnelle sous une large gamme de température imposée et possèdent de très bas coefficients d’expansion thermique.L’objective est l’étude et la compréhension du comportement des liants à base de CAB et PEG quand ils sont utilisés dans les variantes du procédé MIP (étapes de moulage avec ou sans pression, conditions particulières liées à la micro-injection, …) réalisées avec différentes nuances de poudres et différentes granulométries.Les caractéristiques intrinsèques de chaque CAB, leurs interactions avec le PEG et les poudres, l’influence de la nuance de poudre employée, ainsi que la granulométrie et la morphologie des poudres employées ont été étudiées et analysées en fonction du comportement final de la formulation développé et des taux de charges obtenues.L’homogénéité des mélanges développés, leurs taux de charge critique et maximal, ainsi que leurs comportements mécaniques, thermiques et rhéologiques ont été analysés et investigués par différentes études mécaniques, thermo et physico-chimiques. De nouvelles analyses chimiques et physiques ont été introduites par accroitre les connaissances sur les formulations développées. Les formulations optimales ont été validées pour différentes applications et avec l’emploi de différentes variantes du procédé MIP conduisant à l’élaboration de composants et de micro-composants PIM obtenus sans défauts et possédant d’excellentes propriétés fonctionnelles. L’étape de déliantage ainsi que l’étape de densification ont été optimisées en termes de cinétique et d’atmosphère aboutissant aux propriétés physiques et mécaniques escomptées pour l’ensemble des nuances de poudres considérées dans cette étude.En conclusion, les formulations développés des liants basées sur l’emploie de CAB et PEG sont exploitable au niveau de la recherche et au niveau industriel dans le procédé MIP. Elles apportent des améliorations par rapport aux liants conventionnels grâce à un procédé plus écologique. Cette première contribution représente une avancée significative dans l’émergence d’un procédé MIP plus écologique mais d’autres travaux futurs sont encore possibles<br>This PhD Thesis studied the use of binders based on cellulose acetate butyrate (CAB) andpoly(ethylene glycol) (PEG) in different type of materials, including a ceramic, the zirconiumsilicate, and a metallic alloy, the Invar 36. These materials share their low dimensionalstability with temperature with low coefficients of thermal expansion.The scope of this work is the study and comprehension of the behaviour of the mentionedbinder systems when they are employed in different PIM processes and under differentconditions and powder-types. With regard to this matter, different formulations were designedwith several types of PEG and CAB. These formulations were compared with commercialones. The intrinsic characteristics of each CAB were linked with the behaviour of the differentfeedstock also containing PEG and powder particles. The mixtures homogeneity, the optimumand critical solid loading and its flowability were assessed by torque and capillary rheology.Other complementary techniques such as electronic and light microscopy or the measurementof the mixtures densities by pycnometry were carried out to contrast rheology results. Thecompatibility between the feedstocks’ components and their thermal behaviour were analysedby calorimetry and thermogravimetry techniques. These methods were employed by the firsttime to determine the optimal solid loading.The optimal compositions were injected by using low or high pressures or by a micro injectionmoulding process. The debinding and sintering stages were optimised using severalatmospheres. Finally, the physical and mechanical properties of the final consolidated partswere measured.It could be concluded that the studied binder systems based on PEG and CAB presentedsuitable characteristics for PIM, providing improvements with respect to conventional bindersystems and by a more environmental friendly processing. However, that doctoral work wasjust a first approach to the use of these types of binder systems in PIM. Along this workseveral issues were detected and some topics regarding the processing should be furtherinvestigated to obtain the best of these binder systems
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Martyn, Michael T. "Some aspects concerning the powder injection moulding of hardmetal components." Thesis, Loughborough University, 1991. https://dspace.lboro.ac.uk/2134/7157.

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The application of a powder injection moulding process to the production of fully sintered hardmetal components has been studied. Salient, highly interdependent process variables investigated include; powder and binder characteristics, mixing techniques, feedstock rheological characteristics, mould design features, moulding parameters, debinding and sintering parameters. Fundamental studies were conducted to determine the effect of powder and binder characteristics on the powder loading capacity of feedstocks. Various methods of mixing were investigated. The most favourable methods were identified from the rheological response of their respective feedstocks as determined by capillary rheometry. Thermogravimetric analyses were used to; (a) identify binders and feedstocks essig beneficial debinding kinetics, (b) in the study of suitable debinding atmospheres and (c) to develop thermal debinding profiles for selected feedstocks. A spiral mould was used to assess the mouldability and optimum moulding parameters of selected feedstocks. Feedstock properties and mould design features which promoted moulding defects were identified and solutions developed. It was found that the maximum hardmetal powder loading achievable in a given feedstock was dependent on the powder size, size distribution and level of agglomeration. Low viscosity binders with high dielectric permittivities were found to promote highly loaded feedstocks. Feedstock viscosity increased with powder concentration. This relationship was modelled by a simple exponential power function over a narrow range of shear and powder concentration. Compounding methods utilising high shear melt mixing principles were found most effective in producing low viscosity feedstocks of consistent rheological response. Feedstock compositions of high powder concentrations and based on single, crystalline, wax binder systems were found to exhibit a high thermal dependence of viscosity, high activation energies of viscous flow, a high shear sensitivity and tended to segregate when subjected to shear. Such propensities were found detrimental to moulding behaviour. Spiral mould analysis revealed feedstock compositions were sensitive to changes in thermal parameters. Compositions based on multi-component binder systems were found most preferential in producing defect free mouldings of sound integrity and offered favourable debinding characteristics. Thermal debinding of mouldings was only completely effective by careful control of heating rates and when performed in hydrogen rich atmospheres. The reaction order and activation energy of the binder volatilisation was found to be dependent on the level of binder decomposition. Melt wicking was most effective using a hydrated magnesium aluminium silicate substrate. Sintered engineering components were produced by an injection moulding process with near theoretical densities and acceptable microstructures.
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Mitchell, Thomas James. "The ballistics of micro-particles into mucosa and skin." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275252.

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Pinwill, Ian E. "A study of binder removal from powder injection moulded aluminium bodies." Thesis, Brunel University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278405.

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Deng, Yibin. "Investigations on the administration of dry vaccines for epidermal powder injection." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-185720.

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Books on the topic "Lyophilized powder for injection"

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1946-, German Randall M., Wiesner Helmut, and Cornwall Robert G. 1946-, eds. Powder injection molding technologies: Proceedings of PIM98. Innovative Material Solutions, 1998.

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German, Randall M. Powder injection molding: A new manufacturing technique : video illustrations. Metal Powder Industries Federation, 1991.

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German, Randall M. The powder injection molding industry: An industry and market report. Innovative Material Solutions, Inc., 1997.

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Powder Injection Molding Symposium (1992 San Franciso, Calif.). Powder Injection Molding Symposium, 1992: Proceedings of the 1992 Powder Injection Molding Symposium sponsored by the Metal Powder Industries Federation and the American Powder Metallurgy Institute, June 21-26, 1992, San Francisco, California. Metal Powder Industries Federation, 1992.

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German, Randall M. Injection molding of metals and ceramics. Metal Powder Industries Federation, 1997.

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Lall, Chaman. Soft magnetism: Fundamentals for powder metallurgy and metal injection molding. Metal Powder Industries Federation, 1992.

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Pinwill, Ian E. A study of binder removal from powder injection moulded aluminium bodies. Brunel University, 1990.

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M, Kuznet͡sov I͡U. Gazodinamika prot͡sessov vduvanii͡a poroshkov v zhidkiĭ metall. "Metallurgii͡a," Cheli͡abinskoe otd-nie, 1991.

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Hans, Kolaska, Gemeinschaftsausschuss für Pulvermetallurgie (Germany), and Gemeinschaftsausschuss für Hochleistungskeramik (Germany), eds. Fortschritte bei der Formgebung in Pulvermetallurgie und Keramik: Vorträge anlässlich des Symposiums am 28.-29. November 1991 in Hagen. VDI Verlag, 1991.

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International Powder Metallurgy Conference (1988 Orlando, Fla.). Metal injection molding: Preprint of a seminar held at the 1988 International Powder Metallurgy Conference, Orlando, Florida, June 7, 1988. Metal Powder Industries Federation, 1988.

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Book chapters on the topic "Lyophilized powder for injection"

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Tseng, Huan-Chang. "Powder Injection Molding." In Molding Simulation: Theory and Practice. Carl Hanser Verlag GmbH & Co. KG, 2022. http://dx.doi.org/10.1007/978-1-56990-885-3_15.

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Boyun, Huang, and Xu Kuangdi. "Powder Injection Molding." In The ECPH Encyclopedia of Mining and Metallurgy. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-19-0740-1_1459-1.

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Wang, Maw-Ling, Rong-Yeu Chang, and Chia-Hsiang (David) Hsu. "Powder Injection Molding." In Molding Simulation: Theory and Practice. Carl Hanser Verlag GmbH & Co. KG, 2018. http://dx.doi.org/10.3139/9781569906200.015.

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Tseng, Huan-Chang (Ivor). "Powder Injection Molding." In Molding Simulation: Theory and Practice, 2nd ed. Carl Hanser Verlag GmbH & Co. KG, 2022. http://dx.doi.org/10.3139/9781569908853.015.

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Boyun, Huang. "Powder Injection Molding." In The ECPH Encyclopedia of Mining and Metallurgy. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-2086-0_1459.

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Stevenson, James F. "Powder Metal Injection Molding." In Injection Molding. Carl Hanser Verlag GmbH & Co. KG, 2009. http://dx.doi.org/10.3139/9783446433731.009.

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Müller, R. "6 Metal injection moulding." In Powder Metallurgy Data. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/10689123_25.

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Piotter, Volker. "Micro Powder Injection Molding." In Micro Injection Molding. Carl Hanser Verlag GmbH & Co. KG, 2018. http://dx.doi.org/10.1007/978-1-56990-654-5_12.

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Piotter, Volker. "Micro Powder Injection Molding." In Micro Injection Molding. Carl Hanser Verlag GmbH & Co. KG, 2018. http://dx.doi.org/10.3139/9781569906545.012.

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Piotter, Volker, Tobias Benzler, Thomas Gietzelt, Robert Ruprecht, and Jürgen Haußelt. "Micro Powder Injection Molding." In Ceramics - Processing, Reliability, Tribology and Wear. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/3527607293.ch26.

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Conference papers on the topic "Lyophilized powder for injection"

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Onbattuvelli, Valmikanathan P., Sachin Laddha, Seong-Jin Park, Jupiter Palagi de Souza, and Sundar V. Atre. "SIC FOR THE POWDER INJECTION MOLDING OF THERMAL MANAGEMENT DEVICES." In 66º Congresso Anual da ABM. Editora Blucher, 2011. https://doi.org/10.5151/2594-5327-17709.

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Qu, Xinlu, Zhang Yiran, Wenyu Wu, and Xiaojun Liu. "Menu optimization of digital twin system based on user experience: A case study of lyophilized injection workshop." In 2025 Intelligent Human Systems Integration. AHFE International, 2025. https://doi.org/10.54941/ahfe1005833.

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Menus are not only a basic user interface element in digital twin systems, but also a key component to improve system usability, user experience, and operational security. Pie menus have been used in SunView, NEWS, and many other systems since Hopkins pioneered them, but they are not widely used in digital twin systems. Previous studies have shown that its usage efficiency is better than that of linear menus, so this paper takes the lyophilized injection workshop digital twin system as an example to verify the user experience differences between pie menus and linear menus within the digital twin system. According to the function of the production line in the lyophilized powder production workshop, the pie menu and linear menu are designed for the interface of the cartoning robotic arm equipment in the intelligent packaging line, and the usability test is used to quantify the user experience data, and through the reliability and validity test and data analysis, it is concluded that the pie menu is higher than the linear menu in terms of ease of learning, use efficiency, usability, and satisfaction, etc., and that the adoption of the pie menu can help to improve user experience.
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GHODESAWAR, G., MUKHTAR AHMED, and RAVINDRANATH H. "Hepatoprotective assessment of lyophilized neem leaf powder against carbon tetrachloride induced liver toxicity in albino rats." In Seventh International Conference on Advances in Applied Science and Environmental Engineering - ASEE 2017. Institute of Research Engineers and Doctors, 2017. http://dx.doi.org/10.15224/978-1-63248-125-2-02.

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Stanimirovic, I., and Z. Stanimirovic. "Piezoelectric ceramics by powder injection molding." In 2010 27th International Conference on Microelectronics (MIEL 2010). IEEE, 2010. http://dx.doi.org/10.1109/miel.2010.5490494.

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Yao, M., and C. R. Wang. "Micro powder injection molded microchannel array." In Fifth Asia International Symposium on Mechatronics (AISM 2015). Institution of Engineering and Technology, 2015. http://dx.doi.org/10.1049/cp.2015.1592.

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Aizawa, Tatsuhiko, and Takashi Iwai. "Granular Modeling for Powder-Binder Compound Characterization in Powder Injection Molding." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0463.

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Abstract New granular modeling is proposed to deal with the powder morphology. The simple shear viscosity testing is utilized to computationally measure the variation of relative viscosity with increasing shear strain or solid loading ratio of particles. Abrupt increase of non-newtonian viscosity with increasing the loading ratio has close relationship with the forced orientation of irregularly-shaped particles. This interparticle interaction reveals on the effect of powder morphology on the actual viscous behavior of the powder-binder compound in the powder injection molding.
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Yakovlev, A., Ph Bertrand, and I. Smurov. "Multimaterial laser cladding with coaxial powder injection." In ICALEO® 2007: 26th International Congress on Laser Materials Processing, Laser Microprocessing and Nanomanufacturing. Laser Institute of America, 2007. http://dx.doi.org/10.2351/1.5061211.

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Heaney, Donald F. "Powder Injection Molding of Implantable Grade Materials." In ASME 2006 International Manufacturing Science and Engineering Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/msec2006-21049.

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In this paper the attributes of powder injection molding that influence the ability to implant a material are evaluated. Specific emphasis is given to technology readiness of stainless steel, titanium and cobalt chromium alloys since these are the most common alloys that are both implantable and metal injection moldable. Issues such as ductility and strengthening are discussed. Also, component size capability of the technology is discussed since prosthetic replacement pushes the upper size limit of the technology and implantable micro devices that require MEMS (MicroElectroMechanical Systems) scale features push the lower limit.
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Chen, X., Y. C. Lam, K. C. Tam, and S. C. M. Yu. "MOLD-FILLING SIMULATION FOR POWDER INJECTION MOLDING." In Processing and Fabrication of Advanced Materials VIII. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812811431_0120.

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Bose, Animesh. "Powder Injection Molding of Airbag Sensor Components." In International Congress & Exposition. SAE International, 1994. http://dx.doi.org/10.4271/940427.

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Reports on the topic "Lyophilized powder for injection"

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Fan, Liang-Shih, E. Abou-Zeida, Shu-Chien Liang, and Xukun Luo. Handling, transport and dispersion of sorbent powder for in-furnace injection. Final report. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/410336.

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Fan, Liang-Shih, F. Bavarian, R. J. Lee, et al. Handling, transport and dispersion of sorbent powder for in-furnace injection. Third year final report. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10154342.

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Fan, L. S., E. Abou-Zeida, S. C. Liang, and Xukun Luo. Handling, transport and dispersion of sorbent powder for in-furnace injection. Final report, September 1, 1993--August 31, 1994. Office of Scientific and Technical Information (OSTI), 1995. http://dx.doi.org/10.2172/57960.

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Chutimaworapan, Suchada, Chaiyo Chaichantippayuth, and Areerat Laopaksa. Formulation of pharmaceutical products of Garcinia mangostana Linn. extracts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.32.

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Part I: The purpose of the investigation was to develop the extraction process that was simple, practical and giving high yield. The maceration of dried powder of Garcinia mangostana fruit husk with ethyl acetate gave yellow crystalline powder of mangostin. The yield was calculated as 7.47%. The identification of the Garcinia mangostanahusk extract was carried out by thin-layer chromatography (TLC) and differential scanning calorimetry. The TLC of mangostin was done by using the alumina sheet and ethyl acetate: hexane (3:1) as mobile phase. The Rf value as compared with standard mangostin was 0.60. The DSC thermogram showed the board melting range of the crude extract at 165.04-166.80 °C. The quantitative analyses of mangostin were developed using the high performance liquid chromatography (HPLC) and ultraviolet (UV) spectrophotometry. The HPLC system using methanol: water (87:13) as mobile phase, clotrimazole as internal standard and using UV detector at 243 nm. The UV spectrophotometric method was carried out using the UV spectrophotometer at 243 nm. The validation of both systems gave high specificity, linearity, accuracy and precision. The solubility study of mangostin showed the low water insolubility. The water solubility was improving with increasing ethanol content. The in vitro microbiological activity of mangostin to Staphylococcus aureus ATCC 25923 and Streptococcus mutans ATCC KPSK2 was studied. The minimum inhibitory concentrations of the extract were 3 µg/ml and 1.5 µg/ml, respectively. The minimum bactericidal concentrations of the extract was 4 µg/ml and 3 µg/ml, respectively.Part II: The purpose of this study was to develop fast dissolving oral strips containing Garcinia mangostana husk extract. The films consisted of low viscosity hydrophilic polymers such as hydroxypropyl methylcellulose and hydroxypropylcellulose, acesulfame potassium as sweetener, and menthol and eucalyptus oil as flavoring agents. The physical and mechanical properties and dissolution time of film bases were compared with commercial product strips A. From the dissolution time data, it was found that the film prepared from mixed polymer between HPMC 3 cps and HPC LV at ratios 2:1, 3:1, 4:1 and 5:1 were not significantly different from commercial product strips A (p&gt;0.05). The films containing extract were light yellow and had porous surface based on observation from scanning electron microscopy. The dissolution profiles of all formulations showed the rapid release more than 80 percent of mangostin from films within 3-7 minutes and the fastest release was from formulation of HPMC 3 cps and HPC LV at ratio 5:1. Differential scanning calorimetry results exhibited that the Garcinia mangostana extract and additives were not in crystalline form in the films. The fast dissolving oral strips containing Garcinia mangostana husk extract showed in vitro antimicrobial activity against oro-dental bacteria, namely, Staphylococcus aureus aTCC 25923 and Streptococcus mutans ATCC KPSK2. Unter strese conditions at 40 degree Celcius and 75 percent relative humidity, the strips showed a good stability.The purpose of the study was to develop monoglyceride-based drug delivery systems containing Garcinia Mangostana extract. The system is based on the ability of mixtures of monoglyceride (dlyceryl monooleate) and triglycerides to form liquid crystals upon contact with water. The drug delivery systems can be administered by syringe and transformed into high-viscous liquid crystalline phases at the injection site. Ternary phase diagrams were constructed from various triglycerides: sesame oil, soybean oil and olive oil. In this study, monoglyceride-based drug delivery systems were prepared in the ratio of triglycerides: monoglyceride: water as 8: 62: 30 and 12: 58: 30. These systems could sustain release of Garcinia Mangostana husk extract over a period of 48 hr and followed squared root of time kinetics during the initial 24 hr of the release phase, indicating that the rate of release was diffusion-controlled. The system containing sesame oil showed the highest drug release. The increasing triglyceride content did not affect the release profiles. Differential scanning calorimetry results demonstrated that Garcinia Mangostana husk extract could be incorporated into drug delivery systems without causing phase transition. In the in vitro test, monoglyceride-based drug delivery systems containing Garcinia mangostana husk extract did not show the antimicrobial activity probably due to the high lipophilicity of the extract therefore it did not diffuse into the medium. Additionally, the drug delivery systems containing Garcinia mangostana husk extract showed good stability under the stress condition.
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R. Will Grimes, Norman Merriam, L.J. Fahy, et al. 1.PRELIMINARY EVALUATION OF A PROCESS USING PLASMA REACTIONS TO DESULFURIZE HEAVY OILS; 2.PROCESS SUPPORT AND DEVELOPMENT FOR COMPCOAL; 3.MISCIBLE/IMMISCIBLE GAS INJECTION PROCESSES; 4.COMPCOAL: A PROFITABLE PROCESS FOR PRODUCTION OF A STABLE HIGH-BTU FUEL FROM POWDER RIVER BASIN COAL; 5.EVALUATION OF ALTERNATE FREE RADICAL INITIATORS FOR HEAVY OIL/PLASTICS CO-PROCESSING; 6.DEVELOPMENT OF AN ON-LINE ALKALI MONITORING PROBE; 7.DEVELOPMENT OF A PORTABLE DATA ACQUISITION SYSTEM; 8.BENCH-SCALE TESTING AND VERIFICATION OF PYROLYSIS CONCEPT FOR REMEDIATION OF TANK BOTTOMS; 9.HAZ-FLOTE: EX-SITU DECONTAMINATION OF MATERIALS; 10.IN-SITU AMELIORATION OF ACID MINE DRAINAGE PROBLEMS; 11.THE SYNAG PROCESS: COAL COMBUSTION ASH MANAGEMENT OPTION; 12.CONDITIONING AND HYDRATION REACTIONS ASSOCIATED WITH CLEAN COAL TECHNOLOGY ASH DISPOSAL/HYDRATION. Office of Scientific and Technical Information (OSTI), 1999. http://dx.doi.org/10.2172/767235.

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