Academic literature on the topic 'Lysine – Synthesis'

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Journal articles on the topic "Lysine – Synthesis"

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Levitina, E. S., L. F. Godunova, L. N. Kaigorodova, E. I. Karpeiskaya, E. I. Klabunovskii, and D. D. Gogoladze. "Asymmetrical synthesis of lysine derivatives." Bulletin of the Academy of Sciences of the USSR Division of Chemical Science 35, no. 4 (1986): 842–44. http://dx.doi.org/10.1007/bf00954244.

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Jeong, Seongwook, Young Joo Yeon, Eun-Gyu Choi, et al. "Alkaliphilic lysine decarboxylases for effective synthesis of cadaverine from L-lysine." Korean Journal of Chemical Engineering 33, no. 5 (2016): 1530–33. http://dx.doi.org/10.1007/s11814-016-0079-5.

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Henriksen, Peter, Sebastian A. Wagner, Brian T. Weinert, et al. "Proteome-wide Analysis of Lysine Acetylation Suggests its Broad Regulatory Scope in Saccharomyces cerevisiae." Molecular & Cellular Proteomics 11, no. 11 (2012): 1510–22. http://dx.doi.org/10.1074/mcp.m112.017251.

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Post-translational modification of proteins by lysine acetylation plays important regulatory roles in living cells. The budding yeast Saccharomyces cerevisiae is a widely used unicellular eukaryotic model organism in biomedical research. S. cerevisiae contains several evolutionary conserved lysine acetyltransferases and deacetylases. However, only a few dozen acetylation sites in S. cerevisiae are known, presenting a major obstacle for further understanding the regulatory roles of acetylation in this organism. Here we use high resolution mass spectrometry to identify about 4000 lysine acetylat
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Galili, Gad. "Regulation of Lysine and Threonine Synthesis." Plant Cell 7, no. 7 (1995): 899. http://dx.doi.org/10.2307/3870045.

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Shen, Zongxuan, Yawen Zhang, and Yan Chen. "Synthesis of Dye-Labeled Lysine Derivatives." Synthetic Communications 30, no. 14 (2000): 2525–32. http://dx.doi.org/10.1080/00397910008087416.

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Sutherland, Andrew, and Christine L. Willis. "Synthesis of [6-13C]-L-lysine." Journal of Labelled Compounds and Radiopharmaceuticals 38, no. 1 (1996): 95–102. http://dx.doi.org/10.1002/(sici)1099-1344(199601)38:1<95::aid-jlcr816>3.0.co;2-q.

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Ganorkar, Rakesh, Amarnath Natarajan, Ahmed Mamai, and José S. Madalengoitia. "Synthesis of Conformationally Constrained Lysine Analogues." Journal of Organic Chemistry 71, no. 13 (2006): 5004–7. http://dx.doi.org/10.1021/jo060210f.

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Klabunovskii, E. I., E. I. Karpeiskaya, E. S. Levitina, L. F. Godunova, and L. N. Kaigorodova. "Catalytic asymmetric synthesis of L-lysine." Bulletin of the Academy of Sciences of the USSR Division of Chemical Science 34, no. 9 (1985): 1996. http://dx.doi.org/10.1007/bf00953957.

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Athanasiou, Varvara, Pandora Thimi, Melina Liakopoulou та ін. "Synthesis and Characterization of the Novel Nε-9-Fluorenylmethoxycarbonyl-l-Lysine N-Carboxy Anhydride. Synthesis of Well-Defined Linear and Branched Polypeptides". Polymers 12, № 12 (2020): 2819. http://dx.doi.org/10.3390/polym12122819.

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The synthesis of well-defined polypeptides exhibiting complex macromolecular architectures requires the use of monomers that can be orthogonally deprotected, containing primary amines that will be used as the initiator for the Ring Opening Polymerization (ROP) of N-carboxy anhydrides. The synthesis and characterization of the novel monomer Nε-9-Fluorenylmethoxycarbonyl-l-Lysine N-carboxy anhydride (Nε-Fmoc-l-Lysine NCA), as well as the novel linear Poly(Nε-Fmoc-l-Lys)n homopolypeptide and Poly(l-Lysine)78–block–[Poly(l-Lysine)10–graft–Poly(l-Histidine)15] block-graft copolypeptide, are present
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Tesseraud, S., R. Peresson, J. Lopes, and A. M. Chagneau. "Dietary lysine deficiency greatly affects muscle and liver protein turnover in growing chickens." British Journal of Nutrition 75, no. 6 (1996): 853–65. http://dx.doi.org/10.1079/bjn19960191.

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We analysed the respective influences of age and lysine deficiency on skeletal muscle and liver protein turnover. Growing male broilers were fed ad libirum on isoenergetic diets containing 2OO g crude protein/kg which varied in their lysine content (7·7 or 10·1 g/kg). Fractional rates of protein synthesis (FSR) were measured in vivo in the liver and the pectoralis major muscle of 2-, 3- and 4-week-old chickens (flooding dose of l-[143H]phenylalanine). Fractional rates of proteolysis (FBR) were estimated for the same tissues as the difference between synthesis and growth. Over the 2-week period
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Dissertations / Theses on the topic "Lysine – Synthesis"

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Campbell, Robert Alexander. "Lysine biosynthesis : synthesis of enzyme inhibitors and substrates." Thesis, University of Glasgow, 1998. http://theses.gla.ac.uk/3981/.

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Two distinct biosynthetic pathways to the essential amino acid L-lysine (A) are found in nature. The -aminoadipate pathway operates in fungi and yeasts. The diaminopimelate (DAP) pathway occurs in bacteria and higher plants. Our studies were concerned with the DAP pathway and particularly with the first two steps of this pathway. These steps involve condensation of L-aspartate--semialdehyde (ASA) (B) with pyruvate (C) to form L-2,3-dihydrodipicolinic acid (DHDPS) (D) and subsequent reduction to L-2,3,4,5-tetrahydrodipicolinic acid (THDPA) (E). The first step is catalysed by the enzyme dihydrod
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Cherblanc, Fanny. "Synthesis and biological evaluation of histone lysine methyltransferase inhibitors." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/23793.

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The epigenetic component of cancer is now well-established and epigenetic therapeutics targeting histone deacetylase and DNA methyltransferase enzymes have received FDA approval. Histone lysine methyltransferases (HKMTs) are a new and promising epigenetic target class for cancer treatment, but the search for HKMT inhibitors is still in its infancy. First, chaetocin, a fungal metabolite belonging to the 3,6 epidithio-diketopiperazine (ETP) class, was previously described as a specific inhibitor of the HKMT SU(VAR)3 9. Like other ETP molecules however, it exhibits a broad cytotoxicity due to the
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Jamonnak, Nuttara. "Novel N(Epsilon)-Acetyl-Lysine Analogs: Synthesis and Application." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1216313957.

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Brady, Jeffrey Darren. "Studies of the synthesis and metabolism of lysine derived collagen crosslinks." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386301.

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Yang, Jinsong. "Convenient synthesis of caprolactam from lysine alternative of current benzene-based caprolactam production /." Diss., Connect to online resource - MSU authorized users, 2007.

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Barrera, Denise Ann. "Synthesis and characterization of a novel biodegradable polymer--poly (lactic acid-co-lysine)." Thesis, Massachusetts Institute of Technology, 1993. http://hdl.handle.net/1721.1/45741.

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Pallin, T. David. "The development of an enzymatically cleaved Nε lysine protecting group for peptide synthesis". Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/15577.

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Protecting groups of the N<SUP>ε</SUP> animo function of lysine, which are removable under reductive conditions, have been investigated. The development of a lysine Nε </SUP> animo protecting group, compatible with the base labile N<SUP>α</SUP> amino protection strategy of peptide synthesis, is described. The protecting group, based on phenylacetic acid, is cleaved by the enzyme Penicillin Acylase (E.C.3.5.1.11) under very mild conditions. It has been demonstrated that the protecting group is stable to the conditions required for azide fragment condensation strategy. The group has been used to
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Kenyon, Colin Peter. "The dissociation of ammonium salts and their effect on the physiology and biochemistry of L-lysine synthesis by Corynebacterium glutamicum FP6." Thesis, Rhodes University, 1994. http://hdl.handle.net/10962/d1004094.

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The availability and assimilation of NH₄⁺ plays an integral role in the growth of microorganisms and the production of amino acids by these organisms. This study investigated the dissociation of NH₄⁺in aqueous solution, its availability and effect on the enzymes of NH₄⁺ assimilation and its influence on lysine production by Corynebacterium glutamicum.In aqueous solution the extent of dissociation of NH₄C1, {NH₄)₂S0₄ and (NH₄)₂HP0₄ increases with decreasing concentration. A model is proposed for the dissociation of these molecules. It is believed that at very low concentrations, dissociation to
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Steger, Matthias. "Versatile synthesis of inhibitors of the late enzymes in the bacterial pathway to lysine." Thesis, University of Sussex, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264579.

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Sonesten, Victor. "Design and Synthesis of Macrocyclic Peptides as Potential Inhibitors of Lysine-Specific Demethylase 1." Thesis, Uppsala universitet, Institutionen för kemi - BMC, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397428.

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Books on the topic "Lysine – Synthesis"

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Miller, Raya. Synthesis and biological activity of some Maillard reaction products from lysine. Swedish University of Agricultural Sciences, Department of Chemistry and Molecular Biology, 1987.

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Ye, Zhi-Hai. Biosynthesis of lysine in Schizosaccharomyces pombe gene, enzyme relationship and heterologous gene expression. 1987.

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Garrad, Richard C. Lysine biosynthesis in Aspergillus fumigatus, Filobasidiella neoformans and Candida albicans. 1989.

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Zee, Ralph. Molecular characterization of the LYS5 gene from Saccharomyces cerevisiae and its role in lysine biosynthesis. 1991.

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Ford, Richard Allen. Structure and expression of the lys1p+s gene of Schizosaccharomyces pombe. 1993.

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Ford, Richard A. Analysis of bacterial strains and vectors involved in the isolation of the diaminopimelate dehydrogenase gene from Glycine max. 1988.

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Book chapters on the topic "Lysine – Synthesis"

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Brauch, Sebastian, Wouter S. Veldmate, and Floris P. J. T. Rutjes. "Ornithine and Lysine Alkaloids." In From Biosynthesis to Total Synthesis. John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118754085.ch11.

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Poupon, Erwan, Rim Salame, and Lok-Hang Yan. "Biomimetic Synthesis of Ornithine/Arginine and Lysine-Derived Alkaloids: Selected Examples." In Biomimetic Organic Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634606.ch1.

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Arora, Ankita, Wan Zheng, Hongjun Liang, and Abhijit Mishra. "Synthesis of Lysine Mimicking Membrane Active Antimicrobial Polymers." In Advances in Polymer Sciences and Technology. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2568-7_4.

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Tong, Xiao-He, and Anita Hong. "A Highly Efficient Method for Synthesis of Fmoc-Lysine(Mmt)-OH." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_30.

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Hudecz, F., H. Votavova, D. Gaal, et al. "Branched Polypeptides with a Poly(L-Lysine) Backbone: Synthesis, Conformation, and Immunomodulation." In Polymeric Materials in Medication. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4899-2245-8_22.

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Kimura, Yukitaka, Motohiro Shima, Tomoyuki Notsu, Shuji Adachi, and Ryuichi Matsuno. "Trypsin-Catalyzed Synthesis of Oligopeptides Containing Hydrophilic and Essential Amino Acid, L-Lysine." In Developments in Food Engineering. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2674-2_187.

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Tam, James P., Jane C. Spetzler, and C. Rao. "Improved synthesis of N-methyl arginine, N-methyl lysine and the ψCH2NH surrogates for solid phase peptide synthesis." In Peptides. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-010-9066-7_83.

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Kodera, Hiromi, Naoki Nishishita, Yoshiaki Hirano, Yoshiaki Kiso, and Yoshio Hayashi. "Synthesis of Polylactides with Side Chain Functionality: Ring-Opening Polymerimerization of a Homobislactone Prepared from Lysine." In Advances in Experimental Medicine and Biology. Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-73657-0_111.

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Malkar, Navdeep, and Gregg B. Fields. "Synthesis of N α-(Fluoren-9-ylmethoxycarbonyl)-N ε-[(7- methoxycoumarin-4-yl)-acetyl]-L-lysine for Use in Solid-Phase Synthesis of Fluorogenic Substrates." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_18.

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Cooper, Stephen, David Gally, Yuko Suneoka, Melissa Penwell, Kelly Caldwell, and Kelvin Bray. "Peptidoglycan Synthesis in Salmonella Typhimurium." In Bacterial Growth and Lysis. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4757-9359-8_18.

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Conference papers on the topic "Lysine – Synthesis"

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Syukri, M., N. R. Purba, B. R. Hutajulu, D. Alfizah, A. Hutagalung, and Z. Masyithah. "Synthesis N-palmitoyl lysine from palmitate acid and L-lysine used mixed solvent: Effect of temperature and reaction time." In PROCEEDINGS OF THE 5TH INTERNATIONAL SYMPOSIUM ON APPLIED CHEMISTRY 2019. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5134579.

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Li, Shuangyan, Lijuan Hao, Yong Yang, et al. "Synthesis and Characterization of Lysine Modified Chitosan Magnetic Microspheres: A Novel Gene Delivery System." In 2007 First International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2007. http://dx.doi.org/10.1115/mnc2007-21141.

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This paper describes a new formulation of magnetic nanoparticles coated by a novel polymer lysine modified chitosan (CS-lys) as gene carrier. Lysine modified chitosan was synthesized by performing carboxyl of lysine and amido of chitosan in the presence of 1-Ethyl-3-(3-dimethyllaminopropyl) carbodiimide hydrochloride (EDC). The absolute chemistry of the Lysine modified chitosan obtained were characterized using IR and 1H NMR, respectively. The results indicated that many amines of chitosan were modificatied with lysine, and optimized the correlation conditions. The lysine modified chitosan mag
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Traore, Mariam, and William D. Lubell. "Solid-Phase Synthesis of Aza-Lysine Peptide Analogue of Trypsin Substrate." In The 24th American Peptide Symposium. Prompt Scientific Publishing, 2015. http://dx.doi.org/10.17952/24aps.2015.202.

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"Synthesis of Novel Non-Isocyanate Polyhydroxyurethane from L-Lysine and Its Application." In 7th International Conference on Latest Trends in Engineering and Technology. International Institute of Engineers, 2015. http://dx.doi.org/10.15242/iie.e1115053.

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ISMAILOV, Ismail Sagidovich, Nina Vladimirovna TREGUBOVA, Rashid Hasanbievich KOCHKAROV, Anna Victorovna MORGUNOVA, and Natalija Alecseevna DRIZHD. "THE RELATIONSHEEP OF AMINO ACID METABOLISM WITH PRODUCTIVITY OF GROWING YOUNG SHEEP." In RURAL DEVELOPMENT. Aleksandras Stulginskis University, 2018. http://dx.doi.org/10.15544/rd.2017.125.

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A number of studies on digestion of the ruminants have shown the process of synthesis of all the essential amino acids in the rumen (Abu Fadel, 2004; Trukhachev, V., Zlidnev, N. 2008). However, according to some researches, microbial protein is deficient in methionine and lysine. This assumption also proves the need for further study of the influence of balanced amino acids to these diets on the growth, development and productive performance of the ruminants. Scientific approbation of the issues related to establishing the requirements of young sheep in lysine and methionine with cystine and d
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Sowińska, Marta, Przemysław Kalicki, Marta Bochyńska, et al. "New dendrimers exploring lysine and 3,5-dihydroxybenzoic acid as branching elements – synthesis and biological evaluation." In XIIth Conference Biologically Active Peptides. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201113142.

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Li, Yan, and Zhigang Zeng. "Synthesis, Characterization and Bioactivity of Two Rare-Earth Complexes with Schiff Base from Lysine-Salicylaldehyde." In 2015 International Conference on Electronic Science and Automation Control. Atlantis Press, 2015. http://dx.doi.org/10.2991/esac-15.2015.1.

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Tengborn, L., M. Johannessen, and U. Hedner. "FAMILY WITH HYPOPLASMINOGENEMIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643123.

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The propositus, a 2 1/2 year old boy, was found to have splenomegalia at a routine control, but was otherwise in good health. He had in his neonatal period had osteomyelitis in his left leg, compl. with sepsis and shock. His mother had had DVT in her left leg extending to the iliac vein in the puerp. Investigation of the boy and his mother showed a decrease of plasma plasminogen to about 50% of the normal both when assayed immunochem. and amidolyt. using the chrom. subst. S-2251 after activ. with SK. The same was found when using UK as the plasminogen activ. Investigation of 23 other members o
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Huan, X., Y. Legrand, J. Soria, C. Soria, J. Caen, and J. Fareed. "STUDIES ON THE ANTITHROMBOTIC ACTIONS OF A COLLAGEN PEPTIDE IN A DEFINED MODEL OF VENOUS THROMBOSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644496.

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The synthesis and biologic actions of a collagen peptide Lys-Pro-Gly-Glu-Pro-Gly-Pro-Lys (CP) were first reported by Fauvel, et. al. in 1979. This peptide was found to inhibit collagen induced aggregation of platelets and to modulate clot formation and specific collagen induced fibrinogen binding by platelets. CP exhibited antithrombotic actions in a modified venous stasis thrombosis model (rabbit) against defined thrombogenic challenges, (ED50;(IV) 0.5 − 2.5 mg/kg; (SC) 2.5 − 7.5 mg/kg). The antithrombotic actions of this peptide exhibited a short half-life (10 minutes) after IV administratio
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Schrader, Thomas, Paolo Finocchiaro, Thomas Grawe, Salvatore Failla, and Giuseppe Consiglio. "A New Receptor Molecule for Lysine and Histidine in Water � Strong Binding of Basic Amino Acids by a Macrocyclic Host." In The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01919.

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