Academic literature on the topic 'Lysoglycerophospholipids'

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Journal articles on the topic "Lysoglycerophospholipids"

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Sano, Shigeki, Michiyasu Nakao, Kazue Tanaka, and Syuji Kitaike. "Synthesis of Fluorine-Containing Analogues of 1-Lysoglycerophospholipids via Horner–Wadsworth–Emmons Reaction." Synthesis 49, no. 16 (2017): 3654–61. http://dx.doi.org/10.1055/s-0036-1588826.

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An efficient method of synthesizing fluorine-containing analogues of 1-lysoglycerophospholipids (1-LPLs) by introducing a palmitoyl moiety starting from bis(2,2,2-trifluoroethyl)phosphonoacetate (Still–Gennari reagent) is described. The method effectively employs Horner–Wadsworth–Emmons reagents as masked 1-LPL derivatives to prepare a series of analogues of 1-lysophosphatidic acid (1-LPA), 1-lysophosphatidylethanolamine (1-LPE), and 1-lysophosphatidylcholine (1-LPC).
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Mo, Hongnan, Jiashu Han, Jingtong Zhai, et al. "Abstract PO4-13-09: Paclitaxel affects the efficacy of PD-1 blockade by interfering with lipid metabolism reprogramming in patients with breast cancer." Cancer Research 84, no. 9_Supplement (2024): PO4–13–09—PO4–13–09. http://dx.doi.org/10.1158/1538-7445.sabcs23-po4-13-09.

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Abstract Background: The question of how chemotherapeutic drugs affect the efficacy of PD-1/PD-L1 antibodies in patients with breast cancer is still pending. In a previously single-cell sequencing study, we have demonstrated that paclitaxel reduces the level of CXCL13+ T cells and other immune cells critical for atezolizumab to work, leading to inferior efficacy of atezolizumab in triple negative breast cancer (TNBC). How paclitaxel affects these important immune cells remains obscure. Recently, plasma metabolomic and proteomics analysis have shown that patients’ systemic metabolic signatures
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Sevastou, Ioanna, Eleanna Kaffe, Marios-Angelos Mouratis, and Vassilis Aidinis. "Lysoglycerophospholipids in chronic inflammatory disorders: The PLA2/LPC and ATX/LPA axes." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831, no. 1 (2013): 42–60. http://dx.doi.org/10.1016/j.bbalip.2012.07.019.

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Kowalczyk, Tomasz, Joanna Kisluk, Karolina Pietrowska, et al. "The Ability of Metabolomics to Discriminate Non-Small-Cell Lung Cancer Subtypes Depends on the Stage of the Disease and the Type of Material Studied." Cancers 13, no. 13 (2021): 3314. http://dx.doi.org/10.3390/cancers13133314.

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Identification of the NSCLC subtype at an early stage is still quite sophisticated. Metabolomics analysis of tissue and plasma of NSCLC patients may indicate new, and yet unknown, metabolic pathways active in the NSCLC. Our research characterized the metabolomics profile of tissue and plasma of patients with early and advanced NSCLC stage. Samples were subjected to thorough metabolomics analyses using liquid chromatography-mass spectrometry (LC-MS) technique. Tissue and/or plasma samples from 137 NSCLC patients were analyzed. Based on the early stage tissue analysis, more than 200 metabolites
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Galebskaya, L. V., L. V. Vasina, M. A. Galkin, and Yu V. Tarasova. "Viperidae snake venom phospholipase A2 . Biochemical targets for the action of protein in the human blood circulatory system. Part 1 (review of literature)." Scientific Notes of the Pavlov University 28, no. 4 (2022): 22–28. http://dx.doi.org/10.24884/1607-4181-2021-28-4-22-28.

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Snake venoms have been fervently studied for decades for two reasons: 1) high death rate due to snake bites; 2) numerous components of snake venoms prove useful in medicine and treatment of diverse pathologies. Snake venom phospholipases A2 are among the most aggressive toxic proteins often playing the main role in immobilization and killing of snakebite victims. These enzymes catalyze the hydrolysis of glycerophospholipids to produce lysoglycerophospholipids and free fatty acids. But the diversity of phospholipase A2 effects is not limited to their catalytic action. In this review (Part 1), w
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Cas, Michele Dei, Gabriella Roda, Feng Li, and Francesco Secundo. "Functional Lipids in Autoimmune Inflammatory Diseases." International Journal of Molecular Sciences 21, no. 9 (2020): 3074. http://dx.doi.org/10.3390/ijms21093074.

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Lipids are apolar small molecules known not only as components of cell membranes but also, in recent literature, as modulators of different biological functions. Herein, we focused on the bioactive lipids that can influence the immune responses and inflammatory processes regulating vascular hyperreactivity, pain, leukocyte trafficking, and clearance. In the case of excessive pro-inflammatory lipid activity, these lipids also contribute to the transition from acute to chronic inflammation. Based on their biochemical function, these lipids can be divided into different families, including eicosa
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Shi, Qingxin, Shuna Jin, Xingliang Xiang, et al. "The metabolic change in serum lysoglycerophospholipids intervened by triterpenoid saponins from Kuding tea on hyperlipidemic mice." Food & Function 10, no. 12 (2019): 7782–92. http://dx.doi.org/10.1039/c9fo02142f.

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Chen, Guiying, Chengwu Song, Shuna Jin, et al. "An integrated strategy for establishment of metabolite profile of endogenous lysoglycerophospholipids by two LC-MS/MS platforms." Talanta 162 (January 2017): 530–39. http://dx.doi.org/10.1016/j.talanta.2016.10.045.

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Lim, Dong Kyu, Changyeun Mo, Nguyen Phuoc Long, Giyoung Kim, and Sung Won Kwon. "Simultaneous Profiling of Lysoglycerophospholipids in Rice (Oryza sativa L.) Using Direct Infusion-Tandem Mass Spectrometry with Multiple Reaction Monitoring." Journal of Agricultural and Food Chemistry 65, no. 12 (2017): 2628–34. http://dx.doi.org/10.1021/acs.jafc.7b00148.

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Shon, Jong Cheol, Seon Min Lee, Jung-Hoon Jung, et al. "Integrated metabolomics and lipidomics reveals high accumulation of polyunsaturated lysoglycerophospholipids in human lung fibroblasts exposed to fine particulate matter." Ecotoxicology and Environmental Safety 202 (October 2020): 110896. http://dx.doi.org/10.1016/j.ecoenv.2020.110896.

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Book chapters on the topic "Lysoglycerophospholipids"

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"Lysoglycerophospholipids." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_300325.

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Conference papers on the topic "Lysoglycerophospholipids"

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Priolo, Carmen, Stéphane J. H. Ricoult, Damir Khabibullin, et al. "Abstract B06: TSC2 loss induces aberrant choline lysoglycerophospholipid metabolism." In Abstracts: AACR Special Conference: Metabolism and Cancer; June 7-10, 2015; Bellevue, WA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.metca15-b06.

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