Relevant bibliographies by topics / LysR-Type Transcriptional Regulator

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  2. Dissertations / Theses

Academic literature on the topic 'LysR-Type Transcriptional Regulator'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "LysR-Type Transcriptional Regulator"

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Xiao, Gaoping, Jianxin He, and Laurence G. Rahme. "Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry." Microbiology 152, no. 6 (2006): 1679–86. http://dx.doi.org/10.1099/mic.0.28605-0.

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The LysR-type transcriptional regulator MvfR (PqsR) (multiple virulence factor regulator) plays a critical role in Pseudomonas aeruginosa pathogenicity via the transcriptional regulation of multiple quorum-sensing (QS)-regulated virulence factors. LasR activates full mvfR transcription, and MvfR subsequently activates pqsA–E expression. This study identifies and characterizes the key cis-regulatory elements through which mvfR and pqsA–E transcription is regulated in the highly virulent P. aeruginosa strain PA14. Deletion and site-directed mutagenesis indicate that: (1) LasR activates mvfR tran
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Sperandio, Brice, Céline Gautier, Nicolas Pons, Dusko S. Ehrlich, Pierre Renault, and Eric Guédon. "Three Paralogous LysR-Type Transcriptional Regulators Control Sulfur Amino Acid Supply in Streptococcus mutans." Journal of Bacteriology 192, no. 13 (2010): 3464–73. http://dx.doi.org/10.1128/jb.00119-10.

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ABSTRACT The genome of Streptococcus mutans encodes 4 LysR-type transcriptional regulators (LTTRs), three of which, MetR, CysR (cysteine synthesis regulator), and HomR (homocysteine synthesis regulator), are phylogenetically related. MetR was previously shown to control methionine metabolic gene expression. Functional analysis of CysR and HomR was carried out by phenotypical studies and transcriptional analysis. CysR is required to activate the transcription of cysK encoding the cysteine biosynthesis enzyme, tcyABC and gshT genes encoding cysteine and glutathione transporter systems, and homR.
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Seynos-García, E., M. Castañeda-Lucio, J. Muñoz-Rojas, et al. "Loci identification of a N-acyl homoserine lactone type quorum sensing system and a new LysR-type transcriptional regulator associated with antimicrobial activity and swarming in Burkholderia gladioli UAPS07070." Open Life Sciences 14, no. 1 (2019): 165–78. http://dx.doi.org/10.1515/biol-2019-0019.

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AbstractA random transposition mutant library of B. gladioli UAPS07070 was analyzed for searching mutants with impaired microbial antagonism. Three derivates showed diminished antimicrobial activity against a sensitive strain. The mutated loci showed high similarity to the quorum sensing genes of the AHL-synthase and its regulator. Another mutant was affected in a gene coding for a LysrR-type transcriptional regulator. The production of toxoflavin, the most well known antimicrobial-molecule and a major virulence factor of plant-pathogenic B. glumae and B. gladioli was explored. The absence of
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Rashid, M. Mamunur, Yumi Ikawa, and Seiji Tsuge. "GamR, the LysR-Type Galactose Metabolism Regulator, RegulateshrpGene Expression via Transcriptional Activation of Two KeyhrpRegulators, HrpG and HrpX, in Xanthomonas oryzae pv. oryzae." Applied and Environmental Microbiology 82, no. 13 (2016): 3947–58. http://dx.doi.org/10.1128/aem.00513-16.

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ABSTRACTXanthomonas oryzaepv. oryzae is the causal agent of bacterial leaf blight of rice. For the virulence of the bacterium, thehrpgenes, encoding components of the type III secretion system, are indispensable. The expression ofhrpgenes is regulated by two keyhrpregulators, HrpG and HrpX: HrpG regulateshrpX, and HrpX regulates otherhrpgenes. Several other regulators have been shown to be involved in the regulation ofhrpgenes. Here, we found that a LysR-type transcriptional regulator that we named GamR, encoded byXOO_2767ofX. oryzaepv. oryzae strain MAFF311018, positively regulated the transc
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Guillouard, Isabelle, Sandrine Auger, Marie-Françoise Hullo, Farid Chetouani, Antoine Danchin, and Isabelle Martin-Verstraete. "Identification of Bacillus subtilis CysL, a Regulator of the cysJI Operon, Which Encodes Sulfite Reductase." Journal of Bacteriology 184, no. 17 (2002): 4681–89. http://dx.doi.org/10.1128/jb.184.17.4681-4689.2002.

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ABSTRACT The way in which the genes involved in cysteine biosynthesis are regulated is poorly characterized in Bacillus subtilis. We showed that CysL (formerly YwfK), a LysR-type transcriptional regulator, activates the transcription of the cysJI operon, which encodes sulfite reductase. We demonstrated that a cysL mutant and a cysJI mutant have similar phenotypes. Both are unable to grow using sulfate or sulfite as the sulfur source. The level of expression of the cysJI operon is higher in the presence of sulfate, sulfite, or thiosulfate than in the presence of cysteine. Conversely, the transc
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6

Luo, Li, Shi-Yi Yao, Anke Becker, et al. "Two New Sinorhizobium meliloti LysR-Type Transcriptional Regulators Required for Nodulation." Journal of Bacteriology 187, no. 13 (2005): 4562–72. http://dx.doi.org/10.1128/jb.187.13.4562-4572.2005.

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ABSTRACT The establishment of an effective nitrogen-fixing symbiosis between Sinorhizobium meliloti and its legume host alfalfa (Medicago sativa) depends on the timely expression of nodulation genes that are controlled by LysR-type regulators. Ninety putative genes coding for LysR-type transcriptional regulators were identified in the recently sequenced S. meliloti genome. All 90 putative lysR genes were mutagenized using plasmid insertions as a first step toward determining their roles in symbiosis. Two new LysR-type symbiosis regulator genes, lsrA and lsrB, were identified in the screening.
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Tumen-Velasquez, Melissa P., Nicole S. Laniohan, Cory Momany, and Ellen L. Neidle. "Engineering CatM, a LysR-Type Transcriptional Regulator, to Respond Synergistically to Two Effectors." Genes 10, no. 6 (2019): 421. http://dx.doi.org/10.3390/genes10060421.

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The simultaneous response of one transcriptional regulator to different effectors remains largely unexplored. Nevertheless, such interactions can substantially impact gene expression by rapidly integrating cellular signals and by expanding the range of transcriptional responses. In this study, similarities between paralogs were exploited to engineer novel responses in CatM, a regulator that controls benzoate degradation in Acinetobacter baylyi ADP1. One goal was to improve understanding of how its paralog, BenM, activates transcription in response to two compounds (cis,cis-muconate and benzoat
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Muraoka, S., R. Okumura, T. Nonaka, N. Ogawa, K. Miyashita, and T. Senda. "Crystal structure of CbnR, a LysR-type transcriptional regulator." Acta Crystallographica Section A Foundations of Crystallography 58, s1 (2002): c275. http://dx.doi.org/10.1107/s0108767302095971.

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Lochowska, Anna, Roksana Iwanicka-Nowicka, Danuta Plochocka, and Monika M. Hryniewicz. "Functional Dissection of the LysR-type CysB Transcriptional Regulator." Journal of Biological Chemistry 276, no. 3 (2000): 2098–107. http://dx.doi.org/10.1074/jbc.m007192200.

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10

Hernández-Lucas, I., A. L. Gallego-Hernández, S. Encarnación, et al. "The LysR-Type Transcriptional Regulator LeuO Controls Expression of Several Genes in Salmonella enterica Serovar Typhi." Journal of Bacteriology 190, no. 5 (2007): 1658–70. http://dx.doi.org/10.1128/jb.01649-07.

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ABSTRACT LeuO is a LysR-type transcriptional regulator that has been implicated in the bacterial stringent response and in the virulence of Salmonella. A genomic analysis with Salmonella enterica serovar Typhi revealed that LeuO is a positive regulator of OmpS1, OmpS2, AssT, and STY3070. In contrast, LeuO down-regulated the expression of OmpX, Tpx, and STY1978. Transcriptional fusions supported the positive and negative LeuO regulation. Expression of ompS1, assT, and STY3070 was induced in an hns mutant, consistent with the notion that H-NS represses these genes; transcriptional activity was l
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Dissertations / Theses on the topic "LysR-Type Transcriptional Regulator"

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Gong, Wenjie [Verfasser]. "Characterization of the LysR-type Transcriptional Regulator HsdR Gene and Its Adjacent Short-chain Dehydrogenase, Reductase SDRx Gene in Comamonas testosteroni ATCC 11996 / Wenjie Gong." Kiel : Universitätsbibliothek Kiel, 2011. http://d-nb.info/1020244666/34.

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Sheehan, Lauren Marie. "Characterizing the AbcR/VtlR system in the Rhizobiales." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/96536.

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Rhizobiales encompass a diverse group of microbes, ranging from free-living, soil-dwelling bacteria to disease-causing, intracellular pathogens. Although the lifestyle of these organisms vary, many genetic systems are well conserved. One system, named the AbcR/VtlR system, is found throughout rhizobiales, and even extends to bacteria in other orders within the Alphaproteobacteria. The AbcR sRNAs are an example of sibling sRNAs, where two copies of the abcR gene are typically present in the genome. The AbcRs are involved in the negative regulation of ABC-type transport systems, which are impo
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Fragel, Susann Marlies [Verfasser], Karin [Gutachter] Schnetz, Niels [Gutachter] Gehring, and Anke [Gutachter] Becker. "Functional and structural characterization of LeuO, a pleiotropic LysR-type transcription regulator in Escherichia coli / Susann Marlies Fragel ; Gutachter: Karin Schnetz, Niels Gehring, Anke Becker." Köln : Universitäts- und Stadtbibliothek Köln, 2018. http://d-nb.info/1168245923/34.

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Klaponski, Natasha. "Functional characterization of two divergently transcribed genes: ptrA, encoding a LysR-type transcriptional regulator, and scd, encoding a short-chain dehydrogenase in Pseudomonas chlororaphis PA23." 2014. http://hdl.handle.net/1993/23436.

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Pseudomonas chlororaphis PA23 inhibits several root pathogens in both the greenhouse and field. A LysR-type transcriptional regulator (LTTR) called PtrA (Pseudomonas transcriptional regulator A) that is essential for Sclerotinia sclerotiorum antifungal activity was discovered through transposon mutagenesis. P. chlororaphis PA23 produces the antibiotics phenazine 1-carboxylic acid, 2-hydroxyphenazine and pyrrolnitrin, and several additional products that contribute to biocontrol. Phenotypic assays and proteomic analysis have revealed that production of these secondary metabolites are markedly r
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"Oligomerization of the LysR-type transcriptional regulators in Escherichia coli." TEXAS A&M UNIVERSITY, 2009. http://pqdtopen.proquest.com/#viewpdf?dispub=3321969.

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Knapp, Gwendowlyn Sue. "Oligomerization of the lysr-type transcriptional regulators in Escherichia Coli." 2008. http://hdl.handle.net/1969.1/ETD-TAMU-2655.

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Protein-protein interactions regulate and drive biological processes and understanding the assembly of these interactions is important. The LysR-Type Transcriptional Regulators (LTTRs) are a large family of transcriptional regulators found in prokaryotes. I have used the LTTRs as a model for protein specificity. In order to understand a residue’s contribution to oligomerization, alanine-scanning mutagenesis was used to probe the contribution of residues identified from in silico analysis of two proteins: OxyR and CynR. The contribution of the residues to oligomerization was characterized using
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Höfle, Caroline. "Untersuchungen zur genetischen Regulation der CO2-Assimilation in Ralstonia spp." Doctoral thesis, 2005. http://hdl.handle.net/11858/00-1735-0000-0006-ABBB-7.

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