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Journal articles on the topic 'M. spicata has demonstrated promising antioxidant'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Shrutika, Akolkar Vaishnavi Adhalrao Geetanjali Bhale Dr. Bhushan Pimple*. "Mentha Spicata – Scent of Wellness: Investigating the Health Benefits of Spearmint (Mentha Spicata) From Ancient Times to Modern Science." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3182–207. https://doi.org/10.5281/zenodo.15463109.

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Mentha spicata, also referred to as Mentha viridis, is a member of the Lamiaceae family of medicinal plants that is valued for its capacity to produce and release secondary metabolites, mainly essential oils. The aerial components of this plant are used by various populations to create tea, and ethnopharmacological surveys carried out globally have revealed that this tisane has a range of effects. These acts are caused by several compounds found in M. spicata, the biological consequences of which have recently been demonstrated through experiments. M. spicata extracts and essential oils were i

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El Menyiy, Naoual, Hanae Naceiri Mrabti, Nasreddine El Omari, et al. "Medicinal Uses, Phytochemistry, Pharmacology, and Toxicology of Mentha spicata." Evidence-Based Complementary and Alternative Medicine 2022 (April 12, 2022): 1–32. http://dx.doi.org/10.1155/2022/7990508.

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Mentha spicata, also called Mentha viridis, is a medicinal plant of the Lamiaceae family characterized by its potency to synthesize and secret secondary metabolites, essentially essential oils. Different populations use the aerial parts of this plant for tea preparation, and this tisane has shown several effects, according to ethnopharmacological surveys carried out in different areas around the world. These effects are attributed to different compounds of M. spicata, in which their biological effects were recently proved experimentally. Pharmacological properties of M. spicata extracts and es

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Zekri, Nadia, Hanane Elazzouzi, Atika Ailli, et al. "Physicochemical Characterization and Antioxidant Properties of Essential Oils of M. pulegium (L.), M. suaveolens (Ehrh.) and M. spicata (L.) from Moroccan Middle-Atlas." Foods 12, no. 4 (2023): 760. http://dx.doi.org/10.3390/foods12040760.

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The cosmetics and food fields are based on the use of synthetic substances to protect their products against oxidation. However, synthetic antioxidants were reported to have negative effects on human health. The interest to develop natural antioxidants from plants has been growing in recent decades. The aim of this study was to determine the antioxidant properties of three essential oils (EOs) of M. pulegium (L.), M. suaveolens (Ehrh.) and M. spicata (L.) from the Azrou and Ifrane regions. The organoleptic characteristics, yields and physical properties were determined for the selected EOs. Th

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Haghmadad Milani, Maryam, Asghar Mohammadi, Sima Panahirad, et al. "Cerium Oxide Nanoparticles (CeO2 NPs) Enhance Salt Tolerance in Spearmint (Mentha spicata L.) by Boosting the Antioxidant System and Increasing Essential Oil Composition." Plants 13, no. 20 (2024): 2934. http://dx.doi.org/10.3390/plants13202934.

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Salinity represents a considerable environmental risk, exerting deleterious effects on horticultural crops. Nanotechnology has recently emerged as a promising avenue for enhancing plant tolerance to abiotic stress. Among nanoparticles, cerium oxide nanoparticles (CeO2 NPs) have been demonstrated to mitigate certain stress effects, including salinity. In the present study, the impact of CeO2 NPs (0, 25, and 100 mg L−1) on various morphological traits, photosynthetic pigments, biochemical parameters, and the essential oil profile of spearmint plants under moderate (50 mM NaCl) and severe (100 mM

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Karim, Md Rasul, Md Riaz Hosen, Md Shamim, Md Alfaz Hossain, Md Saiful Islam, and Md Mizanur Rahman. "Unveiling antidiarrheal, analgesic, and antioxidant activities of Moringa oleifera (Lam.) flower extract via in vivo and in vitro approaches." Journal of Bioscience and Environment Research 2, no. 2 (2025): 10–15. https://doi.org/10.69517/jber.2025.02.02.0003.

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Moringa oleifera (Lam.), sometimes known as the “miracle tree,” has traditionally been used in folk medicine for a variety of therapeutic uses. This study explored the antidiarrheal, analgesic, and antioxidant properties of M. oleifera flower methanolic extract using in vivo and in vitro methods. A castor oil-induced secretory diarrhea model in Swiss albino mice was used to investigate antidiarrheal efficacy. Analgesic characteristics were assessed using tail-flick and acetic acid-induced writhing assays to investigate central and peripheral analgesic responses, respectively. The antioxidant c

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Sułkowska-Ziaja, Katarzyna, Mateusz Korczyński, Monika Trepa, et al. "A Comparative Study on the Mycelium and Fruiting Body of Meripilus giganteus: Chemical Composition and Biological Activity." Current Issues in Molecular Biology 47, no. 5 (2025): 302. https://doi.org/10.3390/cimb47050302.

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Meripilus giganteus (Pers.) P. Karst. is a basidiomycete fungus known for its bioactive properties, including antioxidant, antimicrobial, and cytotoxic effects. Although research has largely focused on fruiting bodies, mycelium obtained through in vitro culture offers a sustainable and potentially scalable source of bioactive metabolites. This study aimed to compare the chemical composition and biological activity of extracts from the fruiting bodies and mycelium of M. giganteus. Key compound groups were analyzed using high-performance liquid chromatography (HPLC), and biological activity was

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Febriza, Ami, Fityatun Usman, Andi Ulfah Magefirah Rasyid, Hasta Handayani Idrus, and Mohd Helmy Mokhtar. "Potential role of Manilkara Zapota L in treating bacterial infection." PeerJ 12 (August 12, 2024): e17890. http://dx.doi.org/10.7717/peerj.17890.

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The increasing problem of antibiotic resistance in bacteria leads to an urgent need for new antimicrobial agents. Alternative treatments for bacterial infections need to be explored to tackle this issue. Plant-based substances are emerging as promising options. Manilkara zapota L. contains compounds with antibiotic activities, and anti-inflammatory, antitumor, antipyretic, and antioxidant properties. It has medicinal properties and contains bioactive compounds, like tannins, flavonoids, and triterpenoids. This review aimed to comprehensively evaluate the existing literature on the potential me

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Bonamigo, Thaliny, Jaqueline Ferreira Campos, Tamaeh Monteiro Alfredo, et al. "Antioxidant, Cytotoxic, and Toxic Activities of Propolis from Two Native Bees in Brazil:Scaptotrigona depilisandMelipona quadrifasciata anthidioides." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–12. http://dx.doi.org/10.1155/2017/1038153.

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Propolis is a natural mixture of compounds produced by various bee species, including stingless bees. This compound has been shown to exhibit antioxidant, antiproliferative, and antitumor activities. The present study aimed to determine the chemical constituents as well as the antioxidant, cytotoxic, and toxic activities of ethanol extracts of propolis obtained from the stingless beesScaptotrigona depilisandMelipona quadrifasciata anthidioides, which are found in Brazil. Phytosterols, terpenes, phenolic compounds, and tocopherol were identified in the ethanol extracts of propolis (EEPs) in dif

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Kuludeep T S, Bhoomika J N, Pragathi H L, Harshith Gowda, and Viswash G. "Evaluation of Phytochemical Composition and Antifungal Potential of Millingtonia hortensis Leaf Extract." Journal of Pharma Insights and Research 2, no. 5 (2024): 095–103. http://dx.doi.org/10.69613/c4bjyv53.

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Millingtonia hortensis, commonly known as the Indian cork tree, has been traditionally used in Southern Asian medicine for various therapeutic purposes. This study aimed to investigate the antifungal properties of M. hortensis leaf extract and evaluate its potential as a natural alternative to synthetic antifungal agents. Leaf samples were collected, authenticated, and subjected to aqueous and methanolic extraction. Phytochemical screening revealed the presence of alkaloids, flavonoids, cardiac glycosides, terpenoids, tannins, phenolic compounds, and proteins. The antioxidant activity of the e

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Han, Yingying, Wentao Yan, Yuping Hou, Dongmei Wang, and Miao Yu. "Xanthoceras sorbifolia Husk Extract Incorporation for the Improvement in Physical and Antioxidant Properties of Soy Protein Isolate Films." Foods 12, no. 15 (2023): 2842. http://dx.doi.org/10.3390/foods12152842.

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With the increasing awareness of ecological and environmental protection, the research on eco-friendly materials has experienced a considerable increase. The objective of our study was to explore a novel soy protein isolate (SPI) film functionalized with antioxidants extracted from Xanthoceras sorbifolia husk (XSHE) as bio-based active packaging films. The films were evaluated in light of their structure, physical machinery, and antioxidant performance using advanced characterization techniques. The FTIR and microscopy results revealed the hydrogen-bond interaction between the SPI and XSHE and

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Fajar, Mohamad, Wahyu Safriansyah, Muhamad Imam Muhajir, Rani Maharani, and Unang Supratman. "Comparative Studies of Two Indonesian Medicinal Plants, Bidara Upas (Merremia mammosa Lour. Hall.f) and Adas (Foeniculum vulgare Miller): Antioxidant, Antidiabetic, and Antimicrobial Activities." Trends in Sciences 21, no. 8 (2024): 7868. http://dx.doi.org/10.48048/tis.2024.7868.

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Bidara upas (Merremia mammosa) and adas (Foeniculum vulgare Miller) are 2 medicinal plants that grow abundantly in Indonesia. This study investigated the chemical composition and biological activity of M. mammosa and F. vulgare. Phytochemical screening was conducted on both plants. However, only the essential oil of F. vulgare was analyzed for GC spectra. A total of 23 compounds were identified from the essential oil of F. vulgare, with anethole being the main constituent (79.02 %). The extract of M. mammosa had a higher total phenolic content (TPC) and total flavonoid content (TFC) of 50.241

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Mayorga-Ramos, Arianna, Johana Zúñiga-Miranda, Elena Coyago-Cruz, Jorge Heredia-Moya, Jéssica Guamán-Bautista, and Linda P. Guamán. "Phytochemical Composition and Biological Properties of Macleania rupestris Fruit Extract: Insights into Its Antimicrobial and Antioxidant Activity." Antioxidants 14, no. 4 (2025): 394. https://doi.org/10.3390/antiox14040394.

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Macleania rupestris, a fruit-bearing species of the Ericaceae family, has traditionally been used for its potential medicinal properties. Background/Objectives: This study investigates the phytochemical composition and antimicrobial activity of M. rupestris fruit extract, focusing on its antibacterial, antibiofilm, and antifungal effects. Methods: M. rupestris (Kunth) A.C.Sm. berries (code: 4456, Herbario QUPS-Ecuador) were collected from the cloud forest Montano Alto, Cuenca-Ecuador, and the extract was obtained using an ethanolic-based extraction and chemically characterized. The antibacteri

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Rocha-Pimienta, Javier, Javier Espino, Sara Martillanes, and Jonathan Delgado-Adámez. "Essential Oils as Nature’s Dual Powerhouses for Agroindustry and Medicine: Volatile Composition and Bioactivities—Antioxidant, Antimicrobial, and Cytotoxic." Separations 12, no. 6 (2025): 145. https://doi.org/10.3390/separations12060145.

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Essential oils (EOs), which are complex mixtures of plant-derived volatile compounds, have been utilized for centuries in the medical, food, and pharmaceutical industries because of their diverse biological properties. In recent years, there has been growing interest in elucidating the bioactivities of essential oils and their underlying mechanisms of action. This study aimed to investigate the antioxidant, antimicrobial, and cytotoxic characteristics of Laurus nobilis, Eucalyptus camaldulensis, Rosmarinus officinalis, and Mentha suaveolens oils and relate them to their volatile compound conte

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Ali-Shtayeh, Mohammed Saleem, Rana Majed Jamous, Salam Yousef Abu Zaitoun, and Iman Basem Qasem. "In-vitro screening of acetylcholinesterase inhibitory activity of extracts from Palestinian indigenous flora in relation to the treatment of Alzheimer’s disease." Functional Foods in Health and Disease 4, no. 9 (2014): 381. http://dx.doi.org/10.31989/ffhd.v4i9.149.

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Background: Cholinesterase inhibitory therapy serves as a strategy for the treatment of Alzheimer’s disease (AD). Several acetylcholinesterase inhibitors (AChEIs) are used for the symptomatic treatment of AD. These compounds have been reported to have adverse effects, including gastrointestinal disturbances. This study was therefore partly aimed at investigating in vitro possible AChEIs in herbal medicines traditionally used in Palestine to treat cognitive disorders, and to point out the role of these plants as potential sources for development of newly potent and safe natural therapeutic agen

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Bagre, Archana, Narendra Kumar Lariya, and Mohan Lal Kori. "Therapeutic Management of Pulmonary Tuberculosis by Mannosylated Chitosan Ascorbate Microspheres: Preparation and Characterization." Journal of Drug Delivery and Therapeutics 9, no. 3 (2019): 13–25. http://dx.doi.org/10.22270/jddt.v9i3.2805.

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Objective: In this study, biodegradable Chitosan Ascorbate Microsphere (CAMs) and mannosylated chitosan ascorbate microsphere (m-CAMs) prepared for targeting towards alveolar macrophages to treatment of pulmonary tuberculosis.  Significance: Ascorbic acid is an antioxidant and reported killing effect on mycobacterium by induces fenton reaction. This study enlightens the possible benefits of adding antioxidant properties of ascorbic acid with chitosan microsphere to an anti-tuberculosis regimen and mannosylation of microsphere significantly induce the targetability of antitubercular drug

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George, M. Joseph L. Philip A. Paul A. Thomas A. Joseph A. Sneha PK and George V. "α-Amylase Inhibitory Activity and Free Radical Scavenging Activity of Murraya Koeingii Leaves". Environmental Science Archives 4, № 1 (2025): 175–81. https://doi.org/10.5281/zenodo.15070460.

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Murraya koenigii (L.) Spreng, commonly known as curry leaf, has a rich history in traditional medicine, with purported benefits in managing diabetes and other ailments. Murraya koenigii leaves are pinnate with 11 to 21 small, glossy and aromatic leaflets that are bright green in color. The fresh leaves are highly aromatic, with a distinct somewhat citrusy flavour and native to South Asia. This study investigates the dual potential of M. koenigii leaf extracts by evaluating their α-amylase inhibitory activity and free radical scavenging capacity, key factors in hyperglycemia management an

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Fidelis, Kleber Ribeiro, Robson Raion de Vasconcelos Alves, Leydianne Leite de Siqueira Patriota, et al. "Saline Extract from Moringa oleifera Leaves Has Antidepressant and Anxiolytic Effects in Mouse Models." Nutraceuticals 4, no. 1 (2024): 65–81. http://dx.doi.org/10.3390/nutraceuticals4010005.

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Plant extracts can be therapeutic alternatives for depression and anxiety. However, some plant-derived preparations can also be toxic. Moringa oleifera leaves are used in human nutrition due to their high nutritional value and antioxidant activity. This study investigated a saline extract from M. oleifera leaves (MoLE) for secondary metabolites, proteins, cytotoxicity, hemolytic activity, in vivo acute oral toxicity, and neurobehavioral effects. MoLE contains flavonoids (rutin and vitexin), lectin, and a trypsin inhibitor. It is neither cytotoxic nor hemolytic for human cells and did not prese

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Nafie, Mohamed S., Ahmed I. Khodair, Hebat Allah Y. Hassan, et al. "Evaluation of 2-Thioxoimadazolidin-4-one Derivatives as Potent Anti-Cancer Agents through Apoptosis Induction and Antioxidant Activation: In Vitro and In Vivo Approaches." Molecules 27, no. 1 (2021): 83. http://dx.doi.org/10.3390/molecules27010083.

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Background: Hepatocellular carcinoma (HCC) is one of the most widespread malignancies and is reported as the fourth most prevalent cause of cancer deaths worldwide. Therefore, we aimed to investigate the probable mechanistic cytotoxic effect of the promising 2-thioxoimidazolidin-4-one derivative on liver cancer cells using in vitro and in vivo approaches. The compounds were tested for the in vitro cytotoxic activity using MTT assay, and the promising compound was tested in colony forming unit assay, flow cytometric analysis, RT-PCR, Western blotting, in vivo using SEC-carcinoma and in silico t

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Al-Fakeh, Maged S., Munirah S. Alazmi, and Yassine EL-Ghoul. "Preparation and Characterization of Nano-Sized Co(II), Cu(II), Mn(II) and Ni(II) Coordination PAA/Alginate Biopolymers and Study of Their Biological and Anticancer Performance." Crystals 13, no. 7 (2023): 1148. http://dx.doi.org/10.3390/cryst13071148.

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Four of the crosslinked sodium alginate and polyacrylic acid biopolymers based nanoscale metal natural polysaccharides, [M(AG-PAA)Cl(H2O)3], where M = Co(II), Cu(II), Mn(II) and Ni(II), AG = sodium alginate and PAA = polyacrylic acid, have been synthesized and structurally characterized. Because of their numerous biological and pharmacological activities of polysaccharides, including antimicrobial, immunomodulatory, antitumor, antidiabetic, antiviral, antioxidant, hypoglycemic and anticoagulant activities, polysaccharides are one of the near-promising candidates in the biomedical and pharmaceu

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Isah, Musa, Gokhan Zengin, Wan-Nor-Amilah Wan Abdul Wahab, et al. "Antioxidant, enzyme inhibition, toxicity, and molecular docking analysis of <i>Melaleuca cajuputi</i> leaf extract and fractions." Natural Resources for Human Health 4, no. 1 (2023): 89–97. http://dx.doi.org/10.53365/nrfhh/176775.

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<i>Melaleuca cajuputi</i> plant has piqued the interest of researchers due to its pharmacological properties. However, there is scarce information regarding its enzyme inhibitory effects and possible mechanism of action. Thus, this study aimed to investigate the antioxidant, enzyme inhibitory, and potential binding interactions of bioactive components in <i>M. cajuputi</i> extract and fractions with the target enzymes. The 1,1-diphenyl-2-picrylhydrazyl radical scavenging (DPPH) assay was used for the antioxidant activity. The enzyme inhibition potential was assessed usi

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Li, Na, Yida Pang, Jiren Xu, Jeevithan Elango, and Wenhui Wu. "Immunomodulatory Effects of Symplectoteuthis oualaniensis Protamine and Its PEG Derivative on Macrophages: Involvement of PI3K/Akt Signaling, Redox Regulation, and Cell Cycle Modulation." Antioxidants 14, no. 4 (2025): 437. https://doi.org/10.3390/antiox14040437.

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Protamine is a promising marine-derived bioactive compound that is highly arginine-rich and has demonstrated unique advantages in medical and biological research. This study, for the first time, investigates the molecular mechanisms underlying the immunomodulatory effects of Salmon Protamine Sulfate (SPS), Symplectoteuthis oualaniensis Protamine (SOP), and its polyethylene glycol (PEG) derivative (SOP-PEG) on RAW264.7 macrophages. The results demonstrate that both SOP and SOP-PEG significantly enhance the proliferation of RAW264.7 cells by promoting the secretion of pro-inflammatory cytokines

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Okut, Sedat, Murat Ozan, Yusuf Buzdağli, et al. "The Effects of Omega-3 Supplementation Combined with Strength Training on Neuro-Biomarkers, Inflammatory and Antioxidant Responses, and the Lipid Profile in Physically Healthy Adults." Nutrients 17, no. 13 (2025): 2088. https://doi.org/10.3390/nu17132088.

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Objectives: This study aimed to comprehensively investigate the physiological effects of omega-3 fatty acid supplementation combined with resistance training on the lipid profile, inflammatory and antioxidant responses, neuro-biomarkers, and physical performance parameters in physically healthy young adults. Methods: Thirty physically active male participants were randomly assigned to an experimental group (omega-3 + resistance training) or a control group (resistance training only). Over eight weeks, both groups performed a standardized resistance training program three times per week. The ex

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Taibi, Mohamed, Amine Elbouzidi, Douaae Ou-Yahia, et al. "Assessment of the Antioxidant and Antimicrobial Potential of Ptychotis verticillata Duby Essential Oil from Eastern Morocco: An In Vitro and In Silico Analysis." Antibiotics 12, no. 4 (2023): 655. http://dx.doi.org/10.3390/antibiotics12040655.

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Ptychotis verticillata Duby, referred to as Nûnkha in the local language, is a medicinal plant that is native to Morocco. This particular plant is a member of the Apiaceae family and has a longstanding history in traditional medicine and has been utilized for therapeutic purposes by practitioners for generations. The goal of this research is to uncover the phytochemical makeup of the essential oil extracted from P. verticillata, which is indigenous to the Touissite region in Eastern Morocco. The extraction of the essential oil of P. verticillata (PVEO) was accomplished through the use of hydro

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Staniszewski, Adam, and Monika Kordowska-Wiater. "Probiotic Yeasts and How to Find Them—Polish Wines of Spontaneous Fermentation as Source for Potentially Probiotic Yeasts." Foods 12, no. 18 (2023): 3392. http://dx.doi.org/10.3390/foods12183392.

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One approach towards maintaining healthy microbiota in the human gastrointestinal tract is through the consumption of probiotics. Until now, the majority of probiotic research has focused on probiotic bacteria, but over the last few years more and more studies have demonstrated the probiotic properties of yeast, and also of species besides the well-studied Saccharomyces cerevisiae var. boulardii. Probiotic strains have to present the ability to survive in harsh conditions of the host body, like the digestive tract. Must fermentation might be an example of a similar harsh environment. In the pr

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Liu, Xiongxiong, Tong Zheng, Yanyu Bao, et al. "Genistein Implications in Radiotherapy: Kill Two Birds with One Stone." Molecules 30, no. 1 (2025): 188. https://doi.org/10.3390/molecules30010188.

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More than 70% of cancer patients receive radiotherapy during their treatment, with consequent various side effects on normal cells due to high ionizing radiation doses despite tumor shrinkage. To date, many radioprotectors and radiosensitizers have been investigated in preclinical studies, but their use has been hampered by the high toxicity to normal cells or poor tumor radiosensitization effects. Genistein is a naturally occurring isoflavone found in soy products. It selectively sensitizes tumor cells to radiation while protecting normal cells from radiation-induced damage, thus improving th

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Marakhova, Anna, Vera Yu Zhilkina, Alexander Elapov, et al. "The Development of a Method for Obtaining Tripleurospermum inodorum (L.) Sch. Bip. Herb Extract Enriched with Flavonoids and an Evaluation of Its Biological Activity." Plants 13, no. 12 (2024): 1629. http://dx.doi.org/10.3390/plants13121629.

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The development of new drugs derived from plant sources is of significant interest in modern pharmacy. One of the promising plant sources for introduction into pharmaceuticals is Tripleurospermum inodorum (L.) Sch. Bip., also known as Tripleurospermum perforatum (Merat.) M. This plant has been shown to possess various biological activities, including anti-inflammatory, antimicrobial, and antimycotic activities, among others. However, a review of the current literature reveals a paucity of studies investigating the chemical composition of the herb Tripleurospermum inodorum (L.) Sch. Bip. This s

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Karna, Keshab Kumar, Kiran Kumar Soni, Jae Hyung You, et al. "MOTILIPERM Ameliorates Immobilization Stress-Induced Testicular Dysfunction via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway in SD Rats." International Journal of Molecular Sciences 21, no. 13 (2020): 4750. http://dx.doi.org/10.3390/ijms21134750.

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It is well established that physiological stress has an adverse effect on the male reproductive system. Experimental studies have demonstrated the promising effects of MOTILIPERM in male infertility. MOTILIPERM extract is composed of three crude medicinal herbs: Morinda officinalis How (Rubiaceae) roots, Allium cepa L. (Liliaceae) outer scales, and Cuscuta chinensis Lamark (convolvulaceae) seeds. The present study aimed to investigate the possible mechanisms responsible for the effects of MOTILIPERM on testicular dysfunction induced by immobilization stress. Fifty male Sprague Dawley rats were

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Taskeen, Sehar, Muhammad Adnan Hafeez, and Iqra Ikram. "INVESTIGATING THE ROLE OF GINGER TEA ORAC VALUE IN HYPERTENSION MANAGEMENT." Insights-Journal of Health and Rehabilitation 3, no. 3 (Health & Rehab) (2025): 302–10. https://doi.org/10.71000/a4dvwb95.

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Background: Hypertension is a leading modifiable risk factor for cardiovascular diseases, including ischemic heart disease, stroke, and chronic kidney disease, and remains a major cause of global morbidity and mortality. Despite pharmacological advancements, dietary and lifestyle interventions play a crucial role in its management. Ginger, a bioactive-rich plant with high Oxygen Radical Absorbance Capacity (ORAC), has been recognized for its potential cardiovascular benefits. This study investigates the efficacy of ORAC-rich ginger tea in reducing blood pressure, improving lipid profiles, and

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Noonan, Douglas M., Luana Calabrone, Luigi Pistelli, et al. "Abstract 7303: The algal carotenoid diatoxanthin shows anti-cancer and cardio-protective properties: RNA seq analysis of potential targets." Cancer Research 84, no. 6_Supplement (2024): 7303. http://dx.doi.org/10.1158/1538-7445.am2024-7303.

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Abstract Introduction: Natural bioactive pigments are of great interest for human health. Marine organisms are underexplored as source of useful metabolites. Diatoms produce diatoxantin (diatox), a xanthophyll with several properties (chemo-preventive, anti-inflammatory, antioxidant, photoprotective, immunomodulatory), that may have beneficial effects. Doxorubicin (doxo) is still one of the most effective chemotherapeutic drugs used in breast cancer (BC) treatment, but has side effects, particularly cardiotoxicity, mainly due to oxidative stress and cardiomyocyte damage. We have assessed the a

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Garcia, Jacqueline S., Min Huang, Bruno C. Medeiros, and Beverly S. Mitchell. "Preclinical Activity of a New Proteasome Inhibitor, MLN9708, in Acute Myelogenous Leukemias Expressing NPM1 Mutated Protein." Blood 124, no. 21 (2014): 993. http://dx.doi.org/10.1182/blood.v124.21.993.993.

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Abstract ABSTRACT: The nucleophosmin-1 (NPM1) mutation represents the most common genetic lesion (30-35%) in adult acute myeloid leukemia (AML) with the mutation resulting in the cytoplasmic delocalization of the NPM protein (NPMc+, most commonly mutation type A, c.860_863dupTCTG). Outside of conventional chemotherapy, treatment options for those with relapsed disease are extremely limited. We have previously discovered that leukemic cells expressing NPMc+ are preferentially sensitive to the cytotoxic effects of the first generation proteasome inhibitor, bortezomib, as result of the induction

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Vardanian, Iryna, Gayаne Sargsyan, Gayane Martirosyan, et al. "Comprehensive agrobiological and biochemical study of sweet pepper (<i>Capsicum annuum</i> L.) varieties." Functional Food Science - Online ISSN: 2767-3146 5, no. 6 (2025): 205–22. https://doi.org/10.31989/ffs.v5i6.1640.

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Background: Sweet pepper (Capsicum annuum L.) fruits are characterized by a high content of vitamin C, carotenoids, and other biologically active compounds that contribute to their nutritional value. Under protected cultivation conditions, this crop ensures stable production of high-quality fruits regardless of seasonal variability. The identification and selection of cultivars capable of accumulating elevated levels of these compounds are of considerable interest for the agricultural sector and the development of functional food products. Objective: The aim of this study is to conduct a compa

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Lee, Jeongin, Jonghak Kim, Chihyun Hwang, and Hyun-Kon Song. "Interfacial Stability of Ru-Based Li-Rich Layered Oxide Cathode by Guaiacol as an Organic Superoxide Dismutase Mimics." ECS Meeting Abstracts MA2024-02, no. 7 (2024): 1040. https://doi.org/10.1149/ma2024-0271040mtgabs.

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As the battery-based energy storage market develops, the demand for Li-ion batteries (LIBs) with high energy density is increasing, which leads to the development of new electrode materials. Li-rich layered oxides (LLO), Li2MO3 where M represents a transition metal such as Mn, Ru or Ir, are attracting attention as promising cathode materials which deliver high discharge capacities exceed 250 mAh g-1 originated from oxygen redox in addition to typical transition (TM) metal redox. The oxygen redox provides progressive insights for higher energy density cathode, however, the oxygen redox is also

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DASH, SAMIR RANJAN. "A Comparative study on Yield performance of Finger Millet Varieties under rainfed conditions in South Eastern Ghat Zone of Odisha." Journal of Advanced Agriculture & Horticulture Research 1, no. 1 (2021): 17–23. http://dx.doi.org/10.55124/jahr.v1i1.63.

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ABSTRACT Finger millet (Eleusine coracana (L) commonly known as ragi is an important crop used for food, forage and industrial products. Finger millet has a wide ecological and geographical adaptability and resilience to various agro-climatic adversities hence, it is highly suited to drought condition and marginal land and requires low external input in cultivation.. Farmers participatory field demonstrations of ragi variety Arjun and Bhairabi were conducted at two villages ie Pedawada of Malkangiri block and MPV -1 of Kalimela block of Malkangiri district, comprising 40 farmers in clust

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BHAGAT, TANUJA S., ONKAR ABHANG, SNEHAL S. BARAVKAR, POOJA S. BOTHE, MANISHA ZAWARE DR., and SHRIKANT DAREKAR DR. "A Review On Mentha spicata." June 7, 2024. https://doi.org/10.5281/zenodo.14059531.

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Mentha spicata, scientifically known as Mentha viridis, is a member ofthe Lamiaceae family of medicinal plants that is valued for its ability to produceand secrete secondary metabolites, which are essentially essential oils.Different populations employ the aerial parts of this plant for tea preparation,and this tisane (herbal tea) has exhibited several effects, according toethnopharmacological (study of traditional medicine) surveys carried out indifferent places across the world. These actions are ascribed to various M.spicata substances, the biological effects of which have lately beendemons

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Medjeldi, Saida, Nora Benrachou, Sabrina Bouchelaghem, Sélim Jallouli, Nadia Farès, and Salem Elkahoui. "Essential oils and alcohol extracts of Northwest Tunisia M. communis and M. spicata: phytocompounds, antioxidant and antibacterial activities." Current Bioactive Compounds 17 (October 8, 2021). http://dx.doi.org/10.2174/1573407217666211008124528.

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Background: Nowadays, the conventional chemical compounds used in the food, pharmaceutical, and cosmetic sectors have proven to be less efficient from an economic and health point of view. Objective: Research has therefore focused on the isolation of bioactive molecules from plants or microorganisms to remedy this situation. Methods: The study focused on the leaf’s volatile compounds determination from Myrtus communis (McEOs) and Mentha spicata (MsEOs) as well as the evaluation of phytochemical fractions and biological activities from their methanol extracts (McME and MsME). Results: Phenolic

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Raj, Siva Shankar, and Mani Panagal. "Antioxidant Activity of Isolated Bioactive Compound from <i>Mollugo nudicaulis</i>." International Journal of Pharmaceutical Sciences and Drug Research, July 30, 2024, 680–84. http://dx.doi.org/10.25004/ijpsdr.2024.160417.

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Mollugo nudicaulis (M. nudicaulis), a medicinal plant with long history of use in traditional medicine. In the present study focused to explore the in vitro antioxidant potential of 12-(10-carboxydecanoyloxy)-12-oxododecanoic acid (compound-1) isolated and characterized as a specific natural compound from the aerial parts of M. nudicaulis. The results of these in vitro antioxidant assays were promising. Compound-1 demonstrated significant antioxidant activity when compared to the standard drug across all tests, effectively scavenging free radicals. These findings suggest that compound-1 from M

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Zhang, Weiwei, Shunyao Zhuang, and Jianshuang Gao. "Xylitol promotes the antioxidant and biocontrol efficiency of the antagonistic yeast, Meyerozyma guilliermondii." Frontiers in Microbiology 16 (May 9, 2025). https://doi.org/10.3389/fmicb.2025.1545248.

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The biocontrol efficiency of the antagonist yeast Meyerozyma guilliermondii is significantly reduced under oxidative stress in adverse environments. However, effective strategies to improve M. guilliermondii under such abiotic stress remain limited. As an effective protectant of yeasts, xylitol has significant potential to improve the performance of M. guilliermondii under abiotic stress. We investigated xylitol’s effects on the viability and efficiency of M. guilliermondii under oxidative stress. The results showed that 0.5 M and 1 M xylitol significantly enhanced yeast survival, antioxidant

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Singh, Bharat, Pooran Sahu, and Ram Sharma. "Phytochemical Profiling, Anti-inflammatory, Antioxidant and Antimicrobial Effects of Seven Indian Morinda Species." Current Bioactive Compounds 17 (September 21, 2021). http://dx.doi.org/10.2174/1573407217666210921113535.

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Background: The fruits, leaves and roots of Morinda species are used in the treatment of inflammations, cancers, diabetes, psychiatric disorders, bacterial and viral infections. However, no study has been conducted on chemical profiling, anti-inflammatory, antioxidant and antimicrobial potentials of leaves of seven Indian Morinda species. Aim: The study aimed to investigate the anti-inflammatory, antioxidant and antimicrobial effects of methanol extract of seven Indian Morinda species. Material and Methods: The total contents of iridoids, flavonoids, anthraquinone glycosides, triterpenoids, li

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Adepoju, Feyisayo O. "Yoghurt fortification with Moringa oleifera: nutritional and production aspects." Mljekarstvo, December 31, 2024, 3–21. http://dx.doi.org/10.15567/mljekarstvo.2024.0101.

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Yoghurt is a nutrient-dense dairy food product produced by lactic acid bacteria that enhances digestion and nutrient absorption, as well as sustains gut flora. However, it is a low-phenolic food. In addition to being a potential food delivery system, creating unique yoghurts with plant-derived ingredients has become more popular. Increasingly, Moringa oleifera remains a popular phytotherapeutic plant known for its antioxidant properties, given the presence of a wide range of phenolic compounds. Adding M. oleifera to yoghurt, therefore, would enhance both mineral and phenolic compositions, as w

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Manhas, Diksha, and Udayabanu Malairaman. "Impact of Moringa oleifera Hydro-Alcoholic Bark Extract on Diabetic Wound Healing: A Topical Approach." International Journal of Lower Extremity Wounds, December 5, 2024. https://doi.org/10.1177/15347346241297829.

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Purpose The current study was aimed to evaluate the potential of Moringa oleifera against diabetic foot ulcer, where the wound healing is impaired and susceptible to infection. Methods The effects of M. oleifera hydroalcoholic bark extract (MOHE) on different parameters influencing diabetic wound healing were comprehensively investigated including: anti-inflammatory effects, antibacterial properties, antioxidant activity, anti-diabetic properties, and fibroblast proliferation and migration. Furthermore, in vivo studies were conducted in diabetic rats and Zebrafish to investigate the topical ef

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Yan, Zixuan, Shamukaer Alimujiang, Yao Zhang, Jianqiang Zhao, Yunfei Hu, and Wenlong Li. "Recent Advances on the Chemical Composition, Pharmacological Properties, and Product Development of Morus alba." Phytochemical Analysis, May 30, 2025. https://doi.org/10.1002/pca.3544.

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ABSTRACTIntroduction: Morus alba, a member of the Moraceae family, has a long history of medicinal use in China. Its branches, fruits, leaves, and root bark are rich in various bioactive compounds, including flavonoids, alkaloids, and other phytochemicals. These plant parts exhibit a broad spectrum of pharmacological activities, such as antidiabetic, antitumor, antibacterial, and antioxidant effects. Owing to these properties, various parts of M. alba have been developed into functional foods and health products, attracting considerable public and scientific interest. Objectives: This review a

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Echeverry González, Sandra Milena, Anamaria Mendonça Santos, Cláudio Carvalho Santana Júnior, et al. "Natural therapies: a systematic review of the medicinal applications of Passiflora ligularis." Phytochemistry Reviews, March 1, 2025. https://doi.org/10.1007/s11101-025-10087-9.

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Abstract Passiflora ligularis (P. ligularis) is a species of the genus Passiflora distributed from Mexico to Bolivia, particularly along the Andes, found at altitudes between 1500 and 2500 m above sea level. This plant is of significant economic importance due to the commercialization of its fruits as food, and it has also been widely used in folk medicine. This systematic review was conducted, using databases such as PubMed, Scopus, Embase, and Web of Science. The search focused on experimental research articles examining the pharmacological properties of P. ligularis. Studies were included i

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Isibor, P. O., E. Akeredolu, O. B. Samuel, et al. "Comparative Bioaccumulation of PAH and BTEX in Malapterurus electricus (Siluriformes: Malapteruridae) and its Enteric Parasite, Electrotaenia malopteruri Sampled from Lekki Lagoon, Lagos, Nigeria." Brazilian Journal of Biology, October 12, 2020. http://dx.doi.org/10.1590/1519-6984.236827.

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Abstract Contamination of Lekki lagoon by petrogenic chemicals such as polycyclic aromatic hydrocarbons (PAH) and benzene, toluene, ethylbenzene, and xylene (BTEX) has been widely reported. The study was aimed at investigating the bioaccumulation of PAH and BTEX in Malapterurus electricus collected from Lekki lagoon in Lagos, Nigeria. BTEX was analyzed in the intestine, water, and sediment samples using 8260B Agilent 7890B gas chromatograph coupled to a mass spectrometer (GC-MS). While PAHs were tested in the same media using a gas chromatograph coupled to a flame ionization detector (GC-FID).

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Oney-Birol, Signem. "Exogenous L-Carnitine Promotes Plant Growth and Cell Division by Mitigating Genotoxic Damage of Salt Stress." Scientific Reports 9, no. 1 (2019). http://dx.doi.org/10.1038/s41598-019-53542-2.

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AbstractL-carnitine is a fundamental ammonium compound responsible for energy metabolism in all living organisms. It is an oxidative stress regulator, especially in bacteria and yeast and lipid metabolism in plants. Besides its metabolic functions, l-carnitine has detoxification and antioxidant roles in the cells. Due to the complex interrelationship of l-carnitine between lipid metabolism and salinity dependent oxidative stress, this study investigates the exogenous l-carnitine (1 mM) function on seed germination, cell division and chromosome behaviour in barley seeds (Hordeum vulgare L. cv.

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PAULOI, LARBENNO, RAFIDAH MD SALIM, LIEW KANG CHIANG, et al. "GC-MS analysis of bioactive compounds in ethanolic extract on different parts of Ziziphus mauritiana." Biodiversitas Journal of Biological Diversity 25, no. 10 (2024). https://doi.org/10.13057/biodiv/d251006.

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Abstract. Pauloi L, Salmim RM, Chiang LK, Sundang M, Rusdi NA, Maid M, Bakansing SM, Moktar J. 2024. GC-MS analysis of bioactive compounds in ethanolic extract on different parts of Ziziphus mauritiana. Biodiversitas 25: 3442-3453. Ziziphus mauritiana Lam., a tropical fruit-bearing tree commonly known as Bidara tree in Malaysia, has a long and rich history of use in traditional medicine. Cultures across the globe have utilized various parts of the plant, including its leaves, bark, fruit, and roots, to address a wide range of health issues, such as digestive disorders, skin conditions, and inf

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Houssein-Zadeh, Nigar, Leila Sadeghi, and Gholamreza Dehghan. "Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9." Iranian Journal of Pharmaceutical Research 24, no. 1 (2025). https://doi.org/10.5812/ijpr-148332.

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Background: Ellagitannins are well-recognized for their antioxidant, chemopreventive, anti-inflammatory, and neuroprotective efficacy. Due to their poor absorption and extensive catabolism, it is proposed that urolithins, as ellagic acid (EA) metabolites, are the real active molecules exerting these biological functions. Objectives: This research evaluated the inhibitory effects of EA, urolithin A (Uro A), and urolithin B (Uro B) on the activity of recombinant human matrix metalloproteinase 9 (rhMMP-9). Dysregulation of MMP-9 activity is directly involved in various pathologies; therefore, inh

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Sakkaa, Shimaa El, Eman H. Zaghloul, and Khaled M. Ghanem. "Psychobiotic Potential of Gamma-Aminobutyric Acid–Producing Marine Enterococcus faecium SH9 from Marine Shrimp." Probiotics and Antimicrobial Proteins, June 25, 2022. http://dx.doi.org/10.1007/s12602-022-09963-z.

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AbstractPsychobiotics are a novel class of probiotics with potential to confer mental wellness via production of neuroactive compounds such as gamma-aminobutyric acid (GABA). The demand for new biological sources of GABA has increased steadily. Therefore, the current study reports the isolation of 17 presumptive lactic acid bacteria (LAB) from marine samples and their screening for GABA synthesis from monosodium glutamate (MSG) using thin-layer chromatography (TLC). The isolate SH9 was selected as a high GABA producing strain. The GABA content of SH9 cell free supernatant (CFS) was quantitativ

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Farahnak Roudsari, Sahar, Houman Rajabi Islami, Seyed Abdolmajid Mousavi, and Mehdi Shamsaie Mehrgan. "Folic Acid-Coated Nanochitosan Ameliorated the Growth Performance, Hematological Parameters, Antioxidant Status, and Immune Responses of Rainbow Trout (Oncorhynchus mykiss)." Frontiers in Veterinary Science 8 (June 15, 2021). http://dx.doi.org/10.3389/fvets.2021.647722.

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In recent years, chitosan has gained considerable attention due to its favorable properties such as excellent biocompatibility and biodegradability for which it can be used as a health supplement for delivering bioactive compounds in the food industry and nutrition. In the present study, the effect of nanochitosans coated with folic acid (FA) was considered on the growth performance, hematological parameters, antioxidant status, and serum immune responses of rainbow trout (Oncorhynchus mykiss) fingerlings. Graded levels of FA-coated nanochitosan (0, 0.1, 0.25, 0.5, and 1 mg kg−1 diet) were add

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Nazari, Mahtab, and Donald L. Smith. "Mitigation of drought or a combination of heat and drought stress effects on canola by Thuricin 17, a PGPR-produced compound." Frontiers in Sustainable Food Systems 7 (October 2, 2023). http://dx.doi.org/10.3389/fsufs.2023.1237206.

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Plant growth-promoting microorganisms (PGPMs) and the specific compounds they produce have the capacity to mitigate the adverse effects of stressors on plants. An example in this regard is Thuricin 17 (Th17), a signal molecule produced by Bacillus thuringiensis NEB17 (Bt NEB17), a plant growth-promoting rhizobacterium. In this study, we aimed to determine the efficacy of Th17 in mitigating drought and the combination of drought and heat stress in canola [Brassica napus (L.)]. Two of the best Th17 concentrations, 10−9 (Th1) M and 10−11 (Th2) M, were used either as seed treatment plus root drenc

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Suantawee, Tanyawan, Henrique Cheng, and Sirichai Adisakwattana. "Cyanidin, a Natural Anti‐Glycation Agent, Inhibits Methylglyoxal‐ and Glucose‐Mediated Protein Glycation in vitro." FASEB Journal 30, S1 (2016). http://dx.doi.org/10.1096/fasebj.30.1_supplement.692.9.

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IntroductionProtein glycation and advanced glycation end products (AGEs) formation are associated with developing macrovascular and microvascular complications of diabetes mellitus. Cyanidin, a natural anthocyanidin abundant in various fruits and vegetables, has been reported a number of beneficial health effects attributed to its antioxidant properties. However, there are no studies related to the antiglycation activity of cyanidin.ObjectiveThe aim of the study was to investigate the inhibitory activity of cyanidin on in vitro protein glycation in bovine serum albumin (BSA) models; BSA/methyl

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