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Relevant bibliographies by topics / M. tuberculosis - Rifampicin

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Academic literature on the topic 'M. tuberculosis - Rifampicin'

Author: Grafiati

Published: 6 September 2023

Last updated: 31 July 2025

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Journal articles on the topic "M. tuberculosis - Rifampicin"

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Danlami, Mohammed Bashar, Basiru Aliyu, and Grace Samuel. "INCIDENCE OF RIFAMPICIN-RESISTANCE PRESUMPTIVE M. TUBERCULOSIS CASES AMONG OUTPATIENTS IN KEBBI STATE, NIGERIA." African Journal of Infectious Diseases 15, no. 1 (2020): 47–52. http://dx.doi.org/10.21010/ajid.v15i1.6.

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Background: The present study determined the incidence of rifampicin resistance M. tuberculosis among outpatients at the General Hospital Yauri, Kebbi State, Nigeria. Materials and Methods: The study is a cross-sectional study conducted from February 2018 to October 2019. Sociodemographic data were collected from hospital registration books. Rifampicin resistance M. tuberculosis was detected using GeneXpert Model GX-IV following manufacturers' instruction. Descriptive statistics and logistic regression were computed using SPSS version 20. The results were presented as odds ratios with associat

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de la Iglesia, Agustina I., Emma J. Stella, and Héctor R. Morbidoni. "Comparison of the Performances of Two In-House Rapid Methods for Antitubercular Drug Susceptibility Testing." Antimicrobial Agents and Chemotherapy 53, no. 2 (2008): 808–10. http://dx.doi.org/10.1128/aac.00960-08.

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ABSTRACT Resistance to rifampin (rifampicin), isoniazid, and streptomycin of 69 Mycobacterium tuberculosis isolates was analyzed by an in-house method based on mycobacteriophage D29 and a colorimetric micromethod. Both methods showed sensitivity and specificity values ranging from 93% to 100%. These simple methods offer an option for drug resistance assessment of M. tuberculosis.

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АХМЕТОВА, А. Ж., Ж. М. АБИЛОВА, Г. Н. ЖАРЫЛҚАСЫН, А. Р. АКИЛЬЖАНОВА та У. А. КОЖАМКУЛОВ. "ҚАЗАҚСТАНДА ТАРАЛҒАН РИФАМПИЦИН-ТӨЗІМДІ M. TUBERCULOSIS КЛИНИКАЛЫҚ ИЗОЛЯТТАРЫНЫҢ ГЕНЕТИКАЛЫҚ СИПАТТАМАСЫ". Vestnik, № 1(64) (14 квітня 2023): 53–65. http://dx.doi.org/10.53065/j5985-7576-8270-u.

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Лекарственно-устойчивый туберкулез остается актуальной проблемой в здравоохранении Казахстана. Казахстан одна из стран в мире с высоким количеством мультирезистентного туберкулеза, характеризующегося устойчивостью к основным антибиотикам первого ряда – рифампицину и изониазиду. Цель данной работы: определить биологическое разнообразие и охарактеризовать мутации в rpoB гене рифампицин-устойчивых клинических изолятов M. tuberculosis из Казахстана. В данной работе от больных с легочным туберкулезом было собрано 115 клинических изолятов M. tuberculosis, устойчивых к противотуберкулезному препарату

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Petrova, L. V., E. V. Sevastyanova, E. E. Larionova, and T. G. Smirnova. "GENOTYPIC AND PHENOTYPIC COMPARISON OF DRUG RESISTANCE PROFILES OF M. tuberculosis ISOLATES." Вестник ЦНИИТ 7, no. 4 (2023): 23–28. http://dx.doi.org/10.57014/2587-6678-2023-7-4-23-28.

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We conducted a comparative analysis of drug resistance of M. tuberculosis isolates to first-line TB drugs. The diagnostic samples and cultures of M. tuberculosis from TB patients were tested in the Mari El Republic. It was established that the divergence between genotypic and phenotypic isoniazid resistance did not exceed 4%, and rifampicin resistance – 3.9%. In most cases there was lack of mutations associated with resistance to isoniazid or rifampicin in the presence of phenotypic resistance. However, the divergence between results obtained by genotypic and different phenotypic methods was n

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Gautam, Praveen B., Ashwini Mishra, and Santosh Kumar. "Prevalence of rifampicin resistant mycobacterium tuberculosis and associated factors among presumptive tuberculosis patients in eastern Uttar Pradesh: a cross sectional study." International Journal Of Community Medicine And Public Health 5, no. 6 (2018): 2271. http://dx.doi.org/10.18203/2394-6040.ijcmph20182039.

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Background: Drug resistant tuberculosis threatens global TB control and is a major public health problem in several countries and India has the highest tuberculosis in the world. The rifampicin resistance is a good predictor of multidrug resistant tuberculosis. The aim of this study was to determine the prevalence of rifampicin resistance M. tuberculosis and associated factor among presumptive tuberculosis patients in eastern Uttar Pradesh.Methods: A cross-sectional study was conducted from October 2016 to September 2017. Detection of M. tuberculosis and resistance to rifampicin was performed

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Sanzhakov, M. A., O. M. Ipatova, T. I. Torkhovskaya, et al. "Increase of antituberculosis efficiency of rifampicin embedded into phospholipid nanoparticles with sodium oleate." Biomeditsinskaya Khimiya 64, no. 6 (2018): 505–10. http://dx.doi.org/10.18097/pbmc20186406505.

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The formulation of the antituberculosis drug rifampicin embedded into 20-30 nm nanoparticles from soy phosphatidylcholine and sodium oleate, is characterized by greater bioavailability as compared with free drug substance. In this study higher antituberculosis activity of this formulation was shown. Rifampicin in nanoparticles demonstrated more effective inhibition of M. tuberculosis H37Rv growth: minimal inhibiting concentration (MIC) was twice smaller than for free rifampicin. Administration of this preparation to mice with tuberculosis induced by M. tuberculosis Erdman revealed that after 6

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Notopuro, P. B., J. Nugraha, and H. Notopuro. "DETEKSI MOLEKUL MUTASI GEN rpoB MYCOBACTERIUM TUBERCULO SIS PADA DAHAK DENGAN POL YME RASE CHAIN REACTION DAN SINGLE STRAND CONFORMATION POLYMORPHISM." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 16, no. 2 (2018): 81. http://dx.doi.org/10.24293/ijcpml.v16i2.973.

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Tuberculosis is a chronic infectious disease which is found in the developing as well as the developed country. This disease is oneof the community health problems which become the priority programs in the national as well as international health. In the lasttwo decades, they can be found in the emergency tuberculosis problems that is related with the Multi Drug Resistance (MDR) Strain.The detection of rifampicin resistance in M. tuberculosis infection can help clinical laboratory to find the MDR strain. Related to thisproblem the proportional culture method is still the gold standard for rifa

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N. Djide, Nana Juniarti, M. Natsir Djide, Muhammad Nur Amir, and Sartini Sartini. "Aktivitas Antibakteri Ekstrak Kelopak Bunga Rosella Terenkapsulasi Maltodekstrin dan Sinergitasnya dengan Isoniazida dan Rifampisin Terhadap Mycobacterium tuberculosis H37rv." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) 5, no. 2 (2019): 117. http://dx.doi.org/10.22487/j24428744.0.v0.i0.12946.

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First-line drugs (Isoniazid and Rifampicin) for the treatment of tuberculosis are known to have experienced resistance to Mycobacterium tuberculosis. The aim of this study was to determine the minimum inhibitory concentration (MIC) of maltodextrin encapsulated rosella calyx extract and its ability to provide a synergistic effect with Isoniazid (INH) and Rifampicin (RIF) on M. tuberculosis R37rv. Rosella calyxs were macerated using 50% ethanol and encapsulated using maltodextrin. Antibacterial activity was carried out by determining MIC value using Microscopic Observation and Direct Susceptibil

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N. Djide, Nana Juniarti, M. Natsir Djide, Muhammad Nur Amir, and Sartini Sartini. "Aktivitas Antibakteri Ekstrak Kelopak Bunga Rosella Terenkapsulasi Maltodekstrin dan Sinergitasnya dengan Isoniazida dan Rifampisin Terhadap Mycobacterium tuberculosis H37rv." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 5, no. 2 (2019): 117–23. http://dx.doi.org/10.22487/j24428744.2019.v5.i2.12946.

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First-line drugs (Isoniazid and Rifampicin) for the treatment of tuberculosis are known to have experienced resistance to Mycobacterium tuberculosis. The aim of this study was to determine the minimum inhibitory concentration (MIC) of maltodextrin encapsulated rosella calyx extract and its ability to provide a synergistic effect with Isoniazid (INH) and Rifampicin (RIF) on M. tuberculosis R37rv. Rosella calyxs were macerated using 50% ethanol and encapsulated using maltodextrin. Antibacterial activity was carried out by determining MIC value using Microscopic Observation and Direct Susceptibil

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Mohiuddin, Md, and J. Ashraful Haq. "First Line Anti-Tubercular Drug Resistance Pattern of Mycobacterium Tuberculosis Isolated From Specialized Hospitals of Dhaka City." Ibrahim Medical College Journal 8, no. 2 (2016): 41–46. http://dx.doi.org/10.3329/imcj.v8i2.26677.

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The present study was undertaken to determine the drug resistance pattern of M. tuberculosis isolated from 225 pulmonary and 45 extrapulmonary tuberculosis cases. The samples were cultured on Lowenstein Jensen (L-J) media for isolation of M. tuberculosis. Drug resistance to first line anti tubercular drugsnamely isoniazid (INH), rifampicin (RIF), Ethambutol (ETH) and streptomycin (SM) were determined by indirect proportion method. The overall drug resistance of M. tuberculosis was 53.6% to any of the first line anti tubercular drugs. Rate of multi drug resistant tuberculosis (MDR-TB) among the

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Dissertations / Theses on the topic "M. tuberculosis - Rifampicin"

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Bhuju, Sabin [Verfasser], and M. [Akademischer Betreuer] Singh. "Development of novel drug screening assays and molecular characterization of rifampicin and pyrazinamide resistance in Mycobacterium tuberculosis / Sabin Bhuju ; Betreuer: M. Singh." Braunschweig : Technische Universität Braunschweig, 2008. http://d-nb.info/1175828823/34.

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Paiva, Marcelo Vitor de. "Otimiza??o e valida??o de m?todos anal?ticos para a determina??o simult?nea de tuberculost?ticos (4-FDC) por CLAE/DAD e CLUE/ DAD." Universidade Federal do Rio Grande do Norte, 2013. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13477.

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Made available in DSpace on 2014-12-17T14:16:30Z (GMT). No. of bitstreams: 1 MarceloVPA_DISSERT.pdf: 3152615 bytes, checksum: 2a3513c0df769468fec98423bf2dba29 (MD5) Previous issue date: 2013-03-21<br>Tuberculosis is a serious disease, but curable in practically 100% of new cases, since complied the principles of modern chemotherapy. Isoniazid (ISN), Rifampicin (RIF), Pyrazinamide (PYR) and Chloride Ethambutol (ETA) are considered first line drugs in the treatment of tuberculosis, by combining the highest level of efficiency with acceptable degree of toxicity. Concerning USP 33 - NF28 (

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Veldsman, Chrisna. "The prevalence of isoniazid and rifampicin resistance of Mycobacterium tuberculosis." Diss., 2010. http://hdl.handle.net/2263/24638.

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The World Health Organization (WHO) estimated that eight million new cases of tuberculosis (TB) occur every year and that one-third of the world’s population is infected with Mycobacterium tuberculosis (M. tuberculosis). With the increase in HIV/AIDS in the 1980’s, an increase in transmission of TB led to an increase in TB incidence. A study showed that South African adults (ages 15 to 49) will suffer 278 154 deaths between 2008 and 2017 if current control measures are continued. A M. tuberculosis strain that is resistant to isoniazid (INH) and rifampicin (RIF) used in the treatment of TB is k

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Sebastian, Jees. "Response of Mycobacterium Tuberculosis to Rifampicin - A Cellular, Molecular, and Ultrastructural Study." Thesis, 2016. http://etd.iisc.ac.in/handle/2005/3116.

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Tee PhD thesis presents the study of the response of Mycobacterium tuberculosis, the causative agent of tuberculosis, upon prolonged exposure to lethal concentrations of the first line anti-tuberculosis drug, rifampicin. The study shows that prolonged exposure to lethal concentration of rifampicin causes cell death initially by several log orders of cells, followed by a persistence phase, from where rifampicin resisters emerge carrying mutation in the RRDR locus of the rpoB gene. This phenomenon was found to occur even when the drug concentration is well above MBC levels. Luria-Delbruck experi

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Sebastian, Jees. "Response of Mycobacterium Tuberculosis to Rifampicin - A Cellular, Molecular, and Ultrastructural Study." Thesis, 2016. http://hdl.handle.net/2005/3116.

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Tee PhD thesis presents the study of the response of Mycobacterium tuberculosis, the causative agent of tuberculosis, upon prolonged exposure to lethal concentrations of the first line anti-tuberculosis drug, rifampicin. The study shows that prolonged exposure to lethal concentration of rifampicin causes cell death initially by several log orders of cells, followed by a persistence phase, from where rifampicin resisters emerge carrying mutation in the RRDR locus of the rpoB gene. This phenomenon was found to occur even when the drug concentration is well above MBC levels. Luria-Delbruck experi

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Sharmada, S. "Cellular and Molecular Features of the Response of Mycobacterium smegmatis to Rifampicin and Moxifloxacin Upon Prolonged Exposure." Thesis, 2017. http://etd.iisc.ac.in/handle/2005/4168.

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Bacterial persisters are a subpopulation of bacteria that can tolerate lethal concentrations of antibiotics. These are phenotypic variants that can give rise to drug‐susceptible population upon withdrawal of the antibiotic. Persistent bacteria play a crucial role in prolonging antibiotic treatment and are responsible for the recalcitrance of many chronic bacterial diseases, including tuberculosis. Several mechanisms have been proposed for the formation of persisters, which include expression of toxin‐antitoxin systems, generation of reactive oxygen species (ROS), and stochastic changes in gene

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Liu, Shu-feng, and 劉淑鳳. "The epidemiologic comparison of M. avium complex with M. tuberculosis complex and genetic analysis of Rifampicin resistance for M. avium complex of the Infection Disease Hospital in Kaohsiung and Pingtung areas." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/93792242147031238964.

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碩士<br>嘉南藥理科技大學<br>生物科技系暨研究所<br>98<br>Abstract Mycobacterium avium complex (MAC) belongs to a group of slow growing mycobacteria. Many studies showed that chronic pulmonary disease is most commonly manifestated by a non-tuberculous mycobacteria (NTM) infection. MAC, M. kansasii, and M. abscessus, in order of frequency, are the most common pathogens of NTM lung disease. We found the patients with NTM lung disease were more than those with pulmonary tuberculosis between July, 2007 and December, 2008 and MAC was the most common pathogen of NTM lung disease. A case-control was conducted study and 3

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Book chapters on the topic "M. tuberculosis - Rifampicin"

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Boakye-Appiah, Justice, Belinda Hall, Rajko Reljic, and Rachel E. Simmonds. "Current Progress and Prospects for a Buruli Ulcer Vaccine." In Vaccines for Neglected Pathogens: Strategies, Achievements and Challenges. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-24355-4_5.

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AbstractBuruli ulcer (BU), one of the skin-related neglected tropical diseases (skin NTDs), is a necrotizing and disabling cutaneous disease caused by subcutaneous infection with Mycobacterium ulcerans. Leading on from the World Health Organization’s (WHO) establishment of a global BU initiative in 1998, >67,000 cases of BU have been reported from over 32 countries, mostly from West Africa and Australia. While treatment is currently in the transition period from rifampicin plus streptomycin (injection) to an all-oral regimen, it cannot hope to eradicate this opportunistic environmental path

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Dian Novita, Bernadette, Ari Christy Mulyono, and Ferdinand Erwin. "Metformin for Tuberculosis Infection." In Metformin - Pharmacology and Drug Interactions. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99794.

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Tuberculosis, caused by Mycobacterium tuberculosis (M.tb), remains the biggest infection burden in the word. Rifampin (RIF) and Isoniazid (INH) are the most effective antibiotics for killing M.tb. However, the resistance rate of rifampin and INH are high and lead to almost 35% treatment failure. Metformin enhanced anti tuberculosis efficacy in killing M. tuberculosis through several mechanism, firstly through autophagia mechanism and secondly by activating superoxide dismutase (SOD). Metformin activated mTOR and AMPK then induced more effective autophagy against M.tb. Superoxide Dismutase (SOD

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Conference papers on the topic "M. tuberculosis - Rifampicin"

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Vidal, JR, JCG La Torre, and HZ Miguel. "DIAGNÓSTICO MOLECULAR DE TUBERCULOSIS Y EVALUACIÓN DEL GEN RPOB UTILIZANDO GENEXPERT MTB/RIF Y GENEXPERT MTB/RIF ULTRA." In Resumos do 55º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s2.9897.

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Meta: Identificación y análisis de las mutaciones de sondas del gen rpoB de Mycobacterium tuberculosis asociadas a resistencia a rifampicina utilizando GeneXpert MTB/RIF y GeneXpert MTB/RIF Ultra, Lima Perú. Método: Estudio descriptivo y retrospectivo. La población del estudio fue: pacientes adultos, con BK (+), que acudieron a un laboratorio privado de Lima (Perú), con diagnóstico de TBC por GeneXpert MTB/ RIF o GeneXpert MTB/RIF Ultra, con resistencia a la rifampicina, durante el 2014 al 2023. Se utilizó un instrumento de recolección validado, se obtuvo información de la base datos de los eq

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Shurbeska, Boneva, Jasmina Nikolovska, Vladimir Mitrevski, et al. "Following the resistance pattern of mycobacterium tuberculosis." In Proceedings of the International Congress Public Health - Achievements and Challenges. Institute of Public Health of Serbia "Dr Milan Jovanović Batut", 2024. http://dx.doi.org/10.5937/batutphco24029s.

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Background: Tuberculosis (TB) accounts for over 40% of all mortality cases from communicable diseases in Europe.Multidrug-resistant TB (MDR-TB) is TB that does not respond to at least isoniazid and rifampicin, the 2 most powerful anti-TB drugs. 30 countries worldwide are classified as high multi drug resistant (MDR) TB burden countries, nine are in the European Region. The emergence of combined resistance to rifampicin and isoniazid (MDR-TB) is a matter of global concern. Methods and Objectives: Over a period of 10 years we examined patient specimens for TB. Culture-positive samples were subje

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Pompermaier, Carolina, Mateus Xavier Schenato, Tales Antunes Franzini, Fábio Biguelini Duarte, and Guilherme Roloff Cardoso. "TUBERCULOUS LYMPHADENITIS: A LITERATURE REVIEW." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1080.

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Introduction: Lymphadenitis, also previously called “scrofula,” is the most common cause of manifestation of extrapulmonary tuberculosis (TB), an extremely prevalent disease in underdeveloped regions, causing millions of deaths around the world. This is why it must be recognized and treated as early as possible. Objective: This review aims to summarize the main topics of tuberculous lymphadenitis (TL), covering epidemiology, clinical, and recent treatments. Methods: This article consists of a review of publications on the subject. The research was carried out through SciELO, PubMed, and LILACS

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Bisinotto Júnior, Lúcio Mauro, Rosemar Macedo Sousa Rahal, Leonardo Ribeiro Soares, et al. "Chronic non-granulomatous mastitis with positive culture for Mycobacterium tuberculosis." In Brazilian Breast Cancer Symposium 2023. Mastology, 2023. http://dx.doi.org/10.29289/259453942023v33s1056.

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Objective: The objective of this study was to describe a case of chronic mastitis with multiple recurrences and positive culture for Mycobacterium tuberculosis. Methods: The information for this case report was obtained via a consent form, and the study was approved by the Research Ethics Committee of the Universidade Federal de Goiás HC/UFG – GO, with CAAE number: 11983719.0.0000.5078. Results: Patient N.F.R., female, 59 years old, with systemic arterial hypertension, dyslipidemia, and smoker. On July 2020, a hypoechoic, heterogeneous, lobulated mammary nodule was identified on the left, meas

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Santos, Lucas Benicio dos, Ana Cristina Fernandes, Bárbara Rocha Lima, Augusto Bersan Lage Araújo, Gabriel Nascimento de Jesus, and Silvana Spíndola de Miranda. "Prevalência da tuberculose em laboratório de hospital de alta complexidade." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.12333.

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Objetivo: A tuberculose é uma doença infectocontagiosa, milenar e endêmica. É transmitida pelo Mycobacterium tuberculosis. A forma pulmonar e a forma laríngea são as responsáveis pela transmissão da doença quando os resultados fenótipos e/ou genotípicos são positivos. O objetivo deste estudo foi avaliar a prevalência da tuberculose e a sensibilidade aos fármacos de primeira linha em um hospital de alta complexidade. Método: Estudo retrospectivo de banco de dados, de 2022 a março de 2024. Foram consultados os livros de registros do Laboratório de Pesquisa em Micobactérias do Hospital das Clínic

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Mansoor, H., N. Hirani, VV Chavan, et al. "Clinical utility of target-based next-generation sequencing for drug-resistant tuberculosis: a pilot from Mumbai, India." In MSF Scientific Days International 2022. MSF-USA, 2022. http://dx.doi.org/10.57740/atfq-6s03.

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INTRODUCTION In countries with a high tuberculosis (TB) burden, poor access to drug susceptibility testing is a major bottleneck in diagnosing drug-resistant (DR) TB. India is estimated to account for a quarter of multidrug-resistant (MDR)-TB patients globally, with around 124,000 cases in 2020. Mumbai, a densely populated city in Maharashtra State, is a DR-TB hotspot with 24% of treatment- naïve cases, and 41% of previously-treated cases, having MDR-TB, and a high frequency of fluoroquinolone resistance occurring among these MDR-TB cases. Targeted next- generation sequencing (tNGS) is a promi

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Reports on the topic "M. tuberculosis - Rifampicin"

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Tumwasorn, Somying, Ajcharaporn Sawatpanich, Nibondh Udomsantisuk, and Kamon Kawkitinarong. Development of test kit for detection of rifampin resistance in mycobacterium tuberculosis by PCR-reverse line blot hybridization. Faculty of Medicine, Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.25.

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A genetic test by PCR-reverse line blot hybridization was developed for rapid detection of mycobacterium tuberculosis and rifampin resistance simultaneously. Duplex PCR targeting IS 6110 and rpoB gene was employed to detect M. tuberculosis and the rpoB fragment with rifampin resistance hot spot region. The analytical sensitivity of duplex PCR for IS 6110 and rpoB gene was found to be 10 and 100fg of M.Tuberculosis H37Rv DNA, respectively. Since duplex PCR was specific to M. tuberculosis complex, it was thus able to be applied directly in clinical specimens. Oligonucleotide probes were designed

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