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1

Liu, Jie, Tracy J. Ruckwardt, Man Chen, Teresa R. Johnson, and Barney S. Graham. "Characterization of Respiratory Syncytial Virus M- and M2-Specific CD4 T Cells in a Murine Model." Journal of Virology 83, no. 10 (2009): 4934–41. http://dx.doi.org/10.1128/jvi.02140-08.

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ABSTRACT CD4 T cells have been shown to play an important role in the immunity and immunopathogenesis of respiratory syncytial virus (RSV) infection. We identified two novel CD4 T-cell epitopes in the RSV M and M2 proteins with core sequences M213-223 (FKYIKPQSQFI) and M227-37 (YFEWPPHALLV). Peptides containing the epitopes stimulated RSV-specific CD4 T cells to produce gamma interferon (IFN-γ), interleukin 2 (IL-2), and other Th1- and Th2-type cytokines in an I-Ab-restricted pattern. Construction of fluorochrome-conjugated peptide-I-Ab class II tetramers revealed RSV M- and M2-specific CD4 T-
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2

Michel, Christoph, Davood Habibi, and Michael Schmittel. "3-Ethynyl-[1,10]phenanthroline." Molecules 6, no. 6 (2001): M225. http://dx.doi.org/10.3390/m225.

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3

Chao, Hui, Cai-Wu Jiang, Hao Zhang, and Liang-Nian Ji. "(1-(Phenanthrolo[5,6-d]imidazol-2-yl)-3-(4,5-diphenylimidazol-2-yl)benzene." Molbank 2002, no. 1 (2003): M282. http://dx.doi.org/10.3390/m282.

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4

Chao, Hui, Cai-Wu Jiang, Xian-Lan Hong, and Liang-Nian Ji. "2-(2-Hydroxy-5-methyl-3-formylphenyl)-imidazo[4,5-f][1,10]-phenanthroline." Molbank 2002, no. 1 (2003): M285. http://dx.doi.org/10.3390/m285.

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5

Barak, Yoram, Shani Pridan, Yehuda Baruch, and Marnina Swartz. "Poster #M225 AMISULPIRIDE FOR ELDERLY PATIENTS WITH CHRONIC SCHIZOPHRENIA." Schizophrenia Research 153 (April 2014): S271—S272. http://dx.doi.org/10.1016/s0920-9964(14)70775-3.

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6

Leffler, Daniel A., Jessica B. Edwards George, Melinda Dennis, et al. "M2025 A Validated Disease Specific Symptom Index for Adults with Celiac Disease." Gastroenterology 136, no. 5 (2009): A—469. http://dx.doi.org/10.1016/s0016-5085(09)62159-4.

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7

Harvey, Miguel Angel, Sebastián Suarez, Fabio Doctorovich та Ricardo Baggio. "A new polymorph of bis[2,6-bis(1H-benzimidazol-2-yl-κN3)pyridinido-κN]zinc(II)". Acta Crystallographica Section C Crystal Structure Communications 69, № 1 (2012): 47–51. http://dx.doi.org/10.1107/s0108270112050482.

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The title compound, [Zn(C19H12N5)2], crystallizes in the tetragonal space groupP43212, with the monomer residing on a twofold axis. The imidazole N-bound H atoms are disordered over the two positions, with refined occupancies of 0.59 (3) and 0.41 (3). The strong similarities to, and slight differences from, a reportedP42212 polymorph which has a 50% smaller unit-cell volume [Harvey, Baggio, Muñoz & Baggio (2003).Acta Cryst.C59, m283–m285], to which the present structure bears a group–subgroup relationship, are discussed.
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8

Brown, S., H. Danelyan, R. Chepuru, A. Khoylyan, K. Jew, and R. Tachdjian. "M282 HYPEREOSINOPHILIC SYNDROME VS. EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS: THE SYMPTOMATIC DILEMMA." Annals of Allergy, Asthma & Immunology 125, no. 5 (2020): S93—S94. http://dx.doi.org/10.1016/j.anai.2020.08.310.

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9

Ma, Jingtang. "On a Moving Mesh Method for Solving Patial Integro-differential Equations." Journal of Computational Mathematics 27, no. 6 (2009): 713–28. http://dx.doi.org/10.4208/jcm.2009.09-m2852.

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10

Shevchenko, N., E. Morozova, A. Agranovskaya, and T. Plahova. "M285 CERVICAL STATUS BEFORE AND AFTER A SUBTOTAL HYSTERECTOMY IN PATIENTS WITH LEIOMYOMA." International Journal of Gynecology & Obstetrics 119 (October 2012): S623. http://dx.doi.org/10.1016/s0020-7292(12)61476-3.

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11

Oberoi, Shilpa, Rajesambhaji Borade, Neal McCollum, et al. "M2025 Inhibiting Pancreatic Cancer Growth and Sensitizing the Tumor to Radiotherapy Through Downregulation of SP Proteins." Gastroenterology 134, no. 4 (2008): A—453. http://dx.doi.org/10.1016/s0016-5085(08)62118-6.

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12

Askari, H., D. Younesian, and Z. Saadatnia. "Nonlinear Oscillations Analysis of the Elevator Cable in a Drum Drive Elevator System." Advances in Applied Mathematics and Mechanics 7, no. 1 (2015): 43–57. http://dx.doi.org/10.4208/aamm.2013.m225.

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AbstractThis paper aims to investigate nonlinear oscillations of an elevator cable in a drum drive. The governing equation of motion of the objective system is developed by virtue of Lagrangian’s method. A complicated term is broached in the governing equation of the motion of the system owing to existence of multiplication of a quadratic function of velocity with a sinusoidal function of displacement in the kinetic energy of the system. The obtained equation is an example of a well-known category of nonlinear oscillators, namely, non-natural systems. Due to the complex terms in the governing
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13

Ren, Heng, Ning Zhao, and Xi-Yun Lu. "Large Eddy Simulation of a Vortex Ring Impacting a Bump." Advances in Applied Mathematics and Mechanics 6, no. 3 (2014): 261–80. http://dx.doi.org/10.4208/aamm.2013.m285.

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AbstractA vortex ring impacting a three-dimensional bump is studied using large eddy simulation for a Reynolds number Re = 4 × 104 based on the initial diameter and translational speed of the vortex ring. The effects of bump height and vortex core thickness for thin and thick vortex rings on the vortical flow phenomena and the underlying physical mechanisms are investigated. Based on the analysis of the evolution of vortical structures, two typical kinds of vortical structures, i.e., the wrapping vortices and the hair-pin vortices, are identified and play an important role in the flow state ev
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14

Lam, C. W., K. Jain, K. Y. Chan, D. K. Silva, Y. W. Chan, and L. J. C. Wong. "Diagnosis of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes in a Chinese family by PCR/restriction enzyme analysis." Molecular Pathology 48, no. 5 (1995): M285—M288. http://dx.doi.org/10.1136/mp.48.5.m285.

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15

Aractingi, S., E. Gluckman, C. Le Goue, L. Dubertret, and E. D. Carosella. "Lymphocytes, cytokines and adhesion molecules in chronic graft versus host disease." Molecular Pathology 49, no. 4 (1996): M225—M231. http://dx.doi.org/10.1136/mp.49.4.m225.

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16

Yack, H. J., and R. C. Berger. "Dynamic Stability in the Elderly: Identifying a Possible Measure." Journal of Gerontology 48, no. 5 (1993): M225—M230. http://dx.doi.org/10.1093/geronj/48.5.m225.

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17

Suri, D. N., B. L. Egleston, J. A. Brody, and M. A. Rudberg. "Nursing Home Resident Use of Care Directives." Journals of Gerontology Series A: Biological Sciences and Medical Sciences 54, no. 5 (1999): M225—M229. http://dx.doi.org/10.1093/gerona/54.5.m225.

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18

Barzilai, N. "Discovering the Secrets of Successful Longevity." Journals of Gerontology Series A: Biological Sciences and Medical Sciences 58, no. 3 (2003): M225—M226. http://dx.doi.org/10.1093/gerona/58.3.m225.

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19

Dotlic, J., M. Terzic, I. Likic, et al. "M282 NEW MODELS FOR PREOPERATIVE TRIAGE OF WOMEN WITH BENIGN AND MALIGNANT ADNEXAL TUMORS." International Journal of Gynecology & Obstetrics 119 (October 2012): S622. http://dx.doi.org/10.1016/s0020-7292(12)61474-x.

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20

Lichtenberger, F. "M225 SUCCESSFUL TREATMENT OF IVIG RELATED ASEPTIC MENINGITIS WITH COLCHICINE, REPORT OF 3 PATIENTS." Annals of Allergy, Asthma & Immunology 123, no. 5 (2019): S101—S102. http://dx.doi.org/10.1016/j.anai.2019.08.197.

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21

Ohashi-Doi, Katsuyo, Billie Hunne, Dorota Ferens, Nobuyuki Takahashi, and John B. Furness. "M2025 Investigation of Roles of 5-HT2B Receptors in Modulation of Colonic Motility in the Anaesthetized Rat." Gastroenterology 138, no. 5 (2010): S—461. http://dx.doi.org/10.1016/s0016-5085(10)62133-6.

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22

Buckley, R., and E. Wang. "M285 ADULT MALE WITH STAT3 GAIN-OF-FUNCTION MUTATION PREVIOUSLY DIAGNOSED AS COMMON VARIABLE IMMUNODEFICIENCY." Annals of Allergy, Asthma & Immunology 123, no. 5 (2019): S120. http://dx.doi.org/10.1016/j.anai.2019.08.390.

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23

Ngo, S., J. Kelsen, E. De Zoeten, and C. Dutmer. "M282 VERY EARLY-ONSET INFLAMMATORY BOWEL DISEASE IN A PATIENT WITH LEUKOCYTE ADHESION DEFICIENCY TYPE 1." Annals of Allergy, Asthma & Immunology 123, no. 5 (2019): S119—S120. http://dx.doi.org/10.1016/j.anai.2019.08.387.

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24

Rudsenske, N., and J. Perkins. "M225 INCIDENTAL FINDING OF LOW SERUM IGA IN TYPE 1 DIABETES MELLITUS REVEALS DIAGNOSIS OF CVID." Annals of Allergy, Asthma & Immunology 125, no. 5 (2020): S76—S77. http://dx.doi.org/10.1016/j.anai.2020.08.253.

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25

Enweasor, C., A. Nguyen, and S. Teuber. "M285 HETEROZYGOUS RAG1 MUTATIONS ASSOCIATED WITH IMMUNODEFICIENCY, AUTOIMMUNE CYTOPENIAS, AND INDOLENT T CELL LARGE GRANULOCYTIC LEUKEMIA." Annals of Allergy, Asthma & Immunology 125, no. 5 (2020): S94. http://dx.doi.org/10.1016/j.anai.2020.08.313.

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26

J, Ramesh Babu, Ramu A, Vidyadhara S, and Balakrishna T. "Design and Evaluation of Telmisartan SMEDDS for Enhancing Solubility and Dissolution Rate." International Journal of Pharmaceutical Sciences and Nanotechnology 12, no. 6 (2019): 4721–30. http://dx.doi.org/10.37285/ijpsn.2019.12.6.8.

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Telmisartan belongs to a BCS class II drug i.e. low solubility and high permeability. It is an angiotensin II type-I receptor blocker essentially used for the treatment and curing of hypertension. The critical problem facing with telmisartan as it shows low solubility in biological fluids which results into less bioavailability after oral administration. The aim of the present work is to enhance the solubility, dissolution rate of telmisartan by formulating an optimal SMEDDS formulation. SMEDDS were prepared by admixing method using Peceol and Captex 200 as oil phases. Labrafil M2125 as surfac
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27

Ship, J. A., N. E. Nolan, and S. A. Puckett. "Longitudinal Analysis of Parotid and Submandibular Salivary Flow Rates in Healthy, Different-Aged Adults." Journals of Gerontology Series A: Biological Sciences and Medical Sciences 50A, no. 5 (1995): M285—M289. http://dx.doi.org/10.1093/gerona/50a.5.m285.

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28

Rantanen, T., and J. Avela. "Leg Extension Power and Walking Speed in Very Old People Living Independently." Journals of Gerontology Series A: Biological Sciences and Medical Sciences 52A, no. 4 (1997): M225—M231. http://dx.doi.org/10.1093/gerona/52a.4.m225.

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29

Go, Masahiro J., and Spyros Artavanis-Tsakonas. "A Genetic Screen for Novel Components of the Notch Signaling Pathway During Drosophila Bristle Development." Genetics 150, no. 1 (1998): 211–20. http://dx.doi.org/10.1093/genetics/150.1.211.

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Abstract The Notch receptor is the central element in a cell signaling mechanism controlling a broad spectrum of cell fate choices. Genetic modifier screens in Drosophila and subsequent molecular studies have identified several Notch pathway components, but the biochemical nature of signaling is still elusive. Here, we report the results of a genetic modifier screen of the bristle phenotype of a gain-of-function Notch allele, Abruptex16. Abruptex mutations interfere with lateral inhibition/specification events that control the segregation of epidermal and sensory organ precursor lineages, thus
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30

Fyak, Sanjita, Nirmala Pradhan, Sami Lama, Kriti Thapa, and Rajesh Kumar. "M225. EXPRESSED EMOTIONS AND PSYCHOLOGICAL DISTRESS AMONG CAREGIVERS OF PATIENTS WITH CHRONIC MENTAL ILLNESS ATTENDING PSYCHIATRIC DEPARTMENT OF BPKIHS." Schizophrenia Bulletin 46, Supplement_1 (2020): S221—S222. http://dx.doi.org/10.1093/schbul/sbaa030.537.

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Abstract Background Family expressed emotions had been shown to be predictive of outcome in mental illnesses in variety of cultural settings. Distressed caregivers who provide care to mentally ill relatives are at risk for developing mental health disorders. Methods A hospital based cross sectional study was conducted among 85 caregivers of chronic mental illness using purposive sampling technique. Caregivers were interviewed using Family Questionnaire (FQ) and Kessler Psychological Distress Scale (K10) to assess expressed emotions and psychological distress of caregivers respectively. Results
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31

Gunawardana, Jay, Fong Chun Chan, Adele Telenius, et al. "Protein Tyrosine Phosphatase Type-1 (PTPN1) Is Frequently Mutated In Primary Mediastinal B Cell Lymphoma and Hodgkin Lymphoma." Blood 122, no. 21 (2013): 242. http://dx.doi.org/10.1182/blood.v122.21.242.242.

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Abstract Introduction Hodgkin Lymphoma (HL) accounts for 11% of all lymphomas and despite being one of the most curable lymphomas, 20% of HL patients still ultimately die of their disease. Similarly, a proportion of cases of primary mediastinal B cell lymphoma (PMBCL) have refractory disease or early relapse and frequently fail second-line therapy. Development of more targeted therapeutic approaches is impeded by the lack of knowledge about the mutational landscape in the cancer genomes of these lymphomas. PTPN1 is a protein tyrosine phosphatase gene that encodes the protein, PTP1B. PTP1B deph
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32

Bartholdy, Christina, Wieslawa Olszewska, Anette Stryhn, Allan Randrup Thomsen, and Peter J. M. Openshaw. "Gene-gun DNA vaccination aggravates respiratory syncytial virus-induced pneumonitis." Journal of General Virology 85, no. 10 (2004): 3017–26. http://dx.doi.org/10.1099/vir.0.80098-0.

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A CD8+ T-cell memory response to respiratory syncytial virus (RSV) was generated by using a DNA vaccine construct encoding the dominant Kd-restricted epitope from the viral transcription anti-terminator protein M2 (M282–90), linked covalently to human β 2-microglobulin (β 2m). Cutaneous gene-gun immunization of BALB/c mice with this construct induced an antigen-specific CD8+ T-cell memory. After intranasal RSV challenge, accelerated CD8+ T-cell responses were observed in pulmonary lymph nodes and virus clearance from the lungs was enhanced. The construct induced weaker CD8+ T-cell responses th
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33

Han, H., J. Kim, H. Jang, et al. "M225 THE RATE OF VERTICAL TRANSMISSION OF HUMAN PAPILLOMAVIRUS FROM MOTHERS TO INFANTS: RELATIONSHIP BETWEEN INFECTION RATE AND MODE OF DELIVERY." International Journal of Gynecology & Obstetrics 119 (October 2012): S604—S605. http://dx.doi.org/10.1016/s0020-7292(12)61417-9.

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34

Yousry, Carol, Pakinam Mohsen Zikry, Emad Basalious Basalious, and Omaima Naem El-Gazayerly. "Self-nanoemulsifying System Optimization for Higher Terconazole Solubilization and Non-Irritant Ocular Administration." Advanced Pharmaceutical Bulletin 10, no. 3 (2020): 389–98. http://dx.doi.org/10.34172/apb.2020.047.

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Purpose: Eye drops’ formulations of poorly water-soluble drugs, offer the advantage of crossing the lipophilic cornea, but their limited aqueous solubility may lead to low ocular bioavailability limiting their therapeutic uses. Terconazole (TZ) is an antifungal drug with low aqueous solubility, restricting its application in ocular fungal infection. Thus, the aim of the work in this study is to enhance TZ solubilization, permitting better ocular permeation and higher bioavailability. To achieve this goal, different self-nanoemulsifying systems (SNESs) were prepared using different oils, surfac
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35

Krishna, Vamshi M., Vijaya B. Kumar, and Narendar Dudhipala. "In-situ Intestinal Absorption and Pharmacokinetic Investigations of Carvedilol Loaded Supersaturated Self-emulsifying Drug System." Pharmaceutical Nanotechnology 8, no. 3 (2020): 207–24. http://dx.doi.org/10.2174/2211738508666200517121637.

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Background: Carvedilol (CD), a non-selective beta-blocker, is indicated for the management of mild to moderate congestive heart failure. After oral administration, CD is rapidly absorbed with an absolute bioavailability of 18-25% because of low solubility and extensive first-pass metabolism. Objective: The present investigation focused on enhanced oral delivery of CD using supersaturated self-emulsifying drug delivery (SEDDS) system. Methods: Optimized SEDDS consisted of a blend of Oleic acid and Labrafil-M2125 as an oil-phase, Cremophor-RH40, polyethylene glycol-400 and HPMC-E5 as a surfactan
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36

Lee, Sujin, Scott A. Miller, David W. Wright, Michael T. Rock, and James E. Crowe. "Tissue-Specific Regulation of CD8+ T-Lymphocyte Immunodominance in Respiratory Syncytial Virus Infection." Journal of Virology 81, no. 5 (2006): 2349–58. http://dx.doi.org/10.1128/jvi.01910-06.

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ABSTRACT Cytotoxic T lymphocytes (CTLs) are critical for control of respiratory syncytial virus (RSV) infection in humans and mice. To investigate cellular immune responses to infection, it is important to identify major histocompatibility complex (MHC) class I-restricted CTL epitopes. In this study, we identified a new RSV-specific, H-2Kd-restricted subdominant epitope in the M2 protein, M2127-135 (amino acids 127 to 135). This finding allowed us to study the frequency of T lymphocytes responding to two H-2Kd-presented epitopes in the same protein following RSV infection by enzyme-linked immu
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37

Boschma, S. P., G. M. Lodge, and S. Harden. "Establishment and persistence of perennial grass and herb cultivars and lines in a recharge area, North-West Slopes, New South Wales." Crop and Pasture Science 60, no. 8 (2009): 753. http://dx.doi.org/10.1071/cp08357.

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Two adjacent sites, one previously cropped and the other a native pasture, were sown with perennial temperate and tropical grasses and herbs (Expt 1), Phalaris aquatica (phalaris) and Festuca arundinacea (tall fescue) cultivars or lines (Expt 2), and perennial tropical grasses (Expt 3) near Manilla, NSW. Establishment, herbage mass and plant frequency were assessed in 2003–06 to (i) identify cultivars/lines with superior persistence, (ii) detect possible mechanisms required for successful production and persistence in a summer-dominant rainfall environment, and (iii) examine the comparative pe
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38

"Stratigraphical record of Seamer Carr Pollen Sites M285 and E77." Proceedings of the Prehistoric Society 54, S1 (1988): 12. http://dx.doi.org/10.1017/s0079497x00061120.

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39

Da Silva, Jaime A. Teixeira. "Use of COVID-19 as an Illegitimate Excuse, or as a Scape-Goat." Gazeta Médica, December 30, 2020. http://dx.doi.org/10.29315/gm.v7i4.409.

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Dear Gazeta Médica Editors,The SARS-CoV-2 virus, which induced the respiratory coronavirus disease 2019 (COVID-19) pandemic, has already claimed (November 6, 2020) over 1.2 million lives and infected over 48.5 million people globally.1 Societies, economies and personal lives may be affected for years to come, either directly, as a possible yearly resurgence, even with a vaccine, similar to seasonal influenza, as vestigial left-over health (“long COVID”2), or as long-term psycho-sociological effects.3 [...]
 REFERENCES
 
 John Hopkins University. Coronavirus Resource Center. [acc
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40

"Pollen diagram M285 from Seamer Carr based on total tree pollen (excluding Corylus) (cf. Part 2, figure 3)." Proceedings of the Prehistoric Society 54, S1 (1988): 17. http://dx.doi.org/10.1017/s0079497x0006117x.

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