Academic literature on the topic 'MACE (major adverse cardiovascular events)'

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Journal articles on the topic "MACE (major adverse cardiovascular events)"

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Ruiz, Juan I., Bo Zhao, Nicolas Palaskas, et al. "Major Adverse Cardiovascular Events in Patients with Melanoma Receiving Immune Checkpoint Inhibitors." Journal of Immunotherapy and Precision Oncology 8, no. 2 (2025): 1–9. https://doi.org/10.36401/jipo-24-31.

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ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) might increase the risk of major adverse cardiovascular events (MACEs). This study aimed to evaluate the risk of MACE in patients with melanoma after ICI initiation. Methods We conducted a before-after cohort study using claims data from Optum’s deidentified Clinformatics Data Mart Database. We included adult patients with melanoma who received any approved ICI between 2011 and 2021 with a minimum of 12 months of observable data before ICI. The main outcome was time to first MACE (myocardial infarction, coronary revascularization, strok
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Shin, Hong-Joon, Joon-Young Yoon, Young-Ok Na, et al. "Major adverse cardiovascular events and hyperuricemia during tuberculosis treatment." PLOS ONE 18, no. 11 (2023): e0294490. http://dx.doi.org/10.1371/journal.pone.0294490.

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Background Hyperuricemia is common during tuberculosis (TB) treatment, especially in association with pyrazinamide (PZA). This study investigated the relationship between major adverse cardiovascular events (MACEs) and hyperuricemia during TB treatment. Methods We conducted a single-center retrospective cohort study. From January 2010 through June 2017, we assessed all consecutive TB patients at Chonnam National University Hospital in South Korea. Hyperuricemia was defined as serum uric acid levels exceeding 7.0 mg/dL (men) and 6.0 mg/dL (women). Results Of the 1,143 patients included, PZA was
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Lee, Andrew, Jacqueline Henry, and Stuart Atkinson. "Major adverse cardiovascular event risk following androgen deprivation therapy initiation by personal history of cardiovascular events." Journal of Clinical Oncology 41, no. 6_suppl (2023): 351. http://dx.doi.org/10.1200/jco.2023.41.6_suppl.351.

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351 Background: Associations between androgen deprivation therapy (ADT) and increased cardiovascular (CV) risk in prostate cancer (PCa) patients have been reported; however, how many of these major adverse CV events (MACE) are caused by ADT itself has been debated. One risk factor for increased CV risk is a prior history of CV events; an analysis found that each new CV event increased the probability of a future event. This study aims to evaluate the incidence of MACE after ADT initiation for patients with and without a prior medical history of MACE. Methods: Analyses of US electronic medical
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Oh, Tak-Kyu, Hyoung-Won Cho, and In-Ae Song. "Association of Opioid Prescription with Major Adverse Cardiovascular Events: Nationwide Cohort Study." Journal of Clinical Medicine 14, no. 4 (2025): 1205. https://doi.org/10.3390/jcm14041205.

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Background: This study aimed to investigate the association between opioid use and the incidence of major adverse cardiovascular events (MACEs). Methods: This study included adult patients who had received oral or transdermal opioids in 2016. The control group comprised individuals who did not receive opioids in 2016 and was selected using a 1:1 stratified random sampling procedure. A MACE was defined as the occurrence of acute myocardial infarction, stroke, heart failure, or cardiovascular mortality. The primary endpoints were new MACEs and cardiovascular mortality, as evaluated from 1 Januar
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Noumegni, Steve Raoul, Romain Didier, Vincent Mansourati, et al. "Risk Factors for Major Adverse Cardiovascular Events and Major Adverse Limb Events after Venous Thromboembolism: A Large Prospective Cohort Study." Seminars in Thrombosis and Hemostasis 48, no. 04 (2022): 465–80. http://dx.doi.org/10.1055/s-0042-1748152.

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Abstract Background There is an increased risk of arterial events including major adverse cardiovascular events (MACE) and major adverse limb events (MALE) after venous thromboembolism (VTE). However, their risk factors remain little explored. Methods We aimed to determine the risk factors for MACE (acute coronary syndrome/stroke/cardiovascular death) and MALE (limb ischemia/critical limb ischemia/non-traumatic amputation/any limb revascularization) after VTE. Competing risk models (Fine-Gray) were used in a multicenter prospective cohort of 4,940 patients (mean age: 64.6 years and median foll
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Niiranen, Oskari, Juha Virtanen, Ville Rantasalo, Amer Ibrahim, Maarit Venermo, and Harri Hakovirta. "The Association between Major Adverse Cardiovascular Events and Peripheral Artery Disease Burden." Journal of Cardiovascular Development and Disease 11, no. 6 (2024): 157. http://dx.doi.org/10.3390/jcdd11060157.

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Objective: The aim of the present study was to investigate the possible relationship between the segmental burden of lower limb atherosclerosis and Major Adverse Cardiovascular Events (MACEs). Methods: All the consecutive symptomatic peripheral artery disease (PAD) patients admitted for digital subtraction angiography (DSA) at Turku University Hospital department of Vascular Surgery between 1 January 2009 and 30 July 2011 were retrospectively analyzed. Angiography due to symptomatic PAD was used as the index date for the inclusion in the study. The segmental burden of atherosclerosis based on
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van der Woude, J., S. Schreiber, L. Peyrin-Biroulet, et al. "P520 Thromboembolic and major adverse cardiovascular events among patients in the filgotinib clinical trial programme." Journal of Crohn's and Colitis 17, Supplement_1 (2023): i646—i649. http://dx.doi.org/10.1093/ecco-jcc/jjac190.0650.

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Abstract Background The once-daily, oral, Janus kinase 1 preferential inhibitor filgotinib (FIL) is approved for the treatment of moderately to severely active rheumatoid arthritis (RA) and ulcerative colitis (UC) in the UK, the EU and Japan.1 To further understand the safety profile of FIL across indications, we evaluated the risk of major adverse cardiovascular events (MACEs) and venous thromboembolic events (VTEs) in patients treated with FIL 200 mg (FIL200) or FIL 100 mg (FIL100). Methods An integrated analysis was conducted with RA data from five phase 2/3 trials and two long-term extensi
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Moltó-Balado, Pedro, Silvia Reverté-Villarroya, Victor Alonso-Barberán, et al. "Machine Learning Approaches to Predict Major Adverse Cardiovascular Events in Atrial Fibrillation." Technologies 12, no. 2 (2024): 13. http://dx.doi.org/10.3390/technologies12020013.

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The increasing prevalence of atrial fibrillation (AF) and its association with Major Adverse Cardiovascular Events (MACE) presents challenges in early identification and treatment. Although existing risk factors, biomarkers, genetic variants, and imaging parameters predict MACE, emerging factors may be more decisive. Artificial intelligence and machine learning techniques (ML) offer a promising avenue for more effective AF evolution prediction. Five ML models were developed to obtain predictors of MACE in AF patients. Two-thirds of the data were used for training, employing diverse approaches
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Wei, Kai-Che, Cheng-Len Sy, Wen-Hwa Wang, Chia-Ling Wu, Shang-Hung Chang, and Yu-Tung Huang. "Major acute cardiovascular events after dengue infection–A population-based observational study." PLOS Neglected Tropical Diseases 16, no. 2 (2022): e0010134. http://dx.doi.org/10.1371/journal.pntd.0010134.

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Background Dengue virus (DENV) infection may be associated with increased risks of major adverse cardiovascular effect (MACE), but a large-scale study evaluating the association between DENV infection and MACEs is still lacking. Methods and findings All laboratory confirmed dengue cases in Taiwan during 2009 and 2015 were included by CDC notifiable database. The self-controlled case-series design was used to evaluate the association between DENV infection and MACE (including acute myocardial infarction [AMI], heart failure and stroke). The "risk interval" was defined as the first 7 days after
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Villegas-Quintero, Víctor Eder, Rodolfo Rivas-Ruíz, Alexis Alejandro García-Rivero, Pedro Rivera-Lara, and Nelly Berenice González-Tovar. "[Efficacy and safety of atorvastatin in major cardiovascular events: Meta-analysis]." Revista Médica del Instituto Mexicano del Seguro Social 61, Suppl 3 (2023): S407—S415. https://doi.org/10.5281/zenodo.8319748.

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<strong>Abstract&nbsp;</strong><strong>Introduction:</strong> Atorvastatin has been used in the management of dyslipidemia and little is known about the efficacy and safety of high-dose atorvastatin administration for secondary prevention of Major Cardiovascular Events (MACE).Objective: To evaluate the impact of high-dose atorvastatin on secondary prevention of MACE and adverse events.<strong>Material and methods:</strong> A systematic review and meta-analysis of Pubmed, Embase, Bireme and Cochrane Library Plus databases was performed, with a time scope from 1990 to July 2022. Six randomized c
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Dissertations / Theses on the topic "MACE (major adverse cardiovascular events)"

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Viti, Mario. "Automated prediction of major adverse cardiovascular events." Electronic Thesis or Diss., université Paris-Saclay, 2022. http://www.theses.fr/2022UPASG084.

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Dans ce projet de recherche financé en contrat CIFRE avec GE Healthcare, on cherche a prédire les épisodes cardio-vasculaire adverses majeurs (ECAM), c’est à dire typiquement les embolies et les anévrismes dans l’aorte et les artères coronaires, qui donnent lieu a une respectivement à une interruption catastrophique du flux sanguin vers le coeur et donc un infarctus, ou à une hémorragie interne. Les deux types d’épisodes sont extrêmement graves. Lorsqu’un patient est hospitalisé pour une alerte reliée à ces épisodes, il va subir un examen scanner X, injecté ou non, plus ou moins invasif. Un ob
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Paniagua, Iglesias Pilar. "Lesión miocárdica tras la cirugía no cardiaca: Análisis de la cohorte española del estudio VISION." Doctoral thesis, Universitat Autònoma de Barcelona, 2015. http://hdl.handle.net/10803/377468.

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Antecedents: Les complicacions cardiovasculars majors (CCVM) són la principal causa de morbimortalitat en els pacients intervinguts de cirurgia no cardíaca. La complicació més freqüent és la lesió miocàrdia després de la cirurgia no cardíaca (LMCN), definida com qualsevol pic del valor de troponina T (TnT) ≥ 0,03 ng/ml atribuït a isquèmia i que ocorre durant els 30 primers dies de la cirurgia no cardíaca. Objectius: Determinar al nostre entorn la incidència actual de CCVM, comparar la freqüència de complicacions observada amb l'esperada d'acord amb l'índex de risc cardíac revisat (IR
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CHEN, YA-YU, and 陳雅榆. "Aspirin resistance and major adverse cardiovascular events (MACEs)." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/16513813317558746789.

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碩士<br>國立臺北護理健康大學<br>健康事業管理研究所<br>105<br>Background In 1971, Sir John Vane discovered aspirin mechanism of action works as antiplatelet agents. It therefore has been widely used for the prevention of cardiovascular disease and cerebrovascular disease. However, there are still 10-20% of aspirin-treated patients experience recurrent ischemic events within 5 years. Especially, most aspirin-resistant patients have multiple chronic conditions. Therefore, this study aimed to investigate the effect of aspirin resistance in major adverse cardiovascular events. Moreover, studying comorbidities such
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Parvar, Saman Laleh. "Major Adverse Cardiovascular Events and Mortality in Peripheral Artery Disease." Thesis, 2020. http://hdl.handle.net/2440/127013.

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Peripheral artery disease (PAD) is the third most prevalent atherosclerotic disorder after coronary artery and cerebrovascular disease. Irrespective of how it manifests clinically, PAD is consistently linked with excessive rates of major adverse cardiovascular events (MACE) and mortality. This thesis examines many contributing factors and provides new insights into the management of patients with this condition. The introductory chapter considers the evidence for treating individual risk factors and the prescription of guideline-recommended medications in PAD. Many prior observational studies
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Hussein, Sharif. "Der Einfluss psychischer Faktoren auf die Prognose nach perkutaner Koronarintervention." Doctoral thesis, 2015. http://hdl.handle.net/11858/00-1735-0000-0022-5FEB-A.

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Books on the topic "MACE (major adverse cardiovascular events)"

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Pelliccia, Antonio, Hein Heidbuchel, Domenico Corrado, Mats Borjesson, and Sanjay Sharma, eds. The ESC Textbook of Sports Cardiology. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198779742.001.0001.

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Sport and exercise have been intensely advocated as protective lifestyle measures, preventing or reducing the risk of severe health issues including cardiovascular disease. More extreme forms of sport (for instance at high altitudes) have been identified as an important way of promoting cardiovascular adaptation, but have also been associated with adverse effects and even major cardiovascular events. More commonplace sport and exercise may also increase an individual’s risk of cardiac events. This publication is timely in the light of an increasing number of clinical papers in this field. The
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Klingenberg, Roland, and Ulf Müller-Ladner. Mechanisms of inflammation. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0270.

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This chapter provides a brief summary of the immune pathogenesis of atherosclerosis, highlighting shared features with inflammatory pathways in rheumatoid arthritis (RA) described in detail in Chapter 25.4. RA constitutes a prototype autoimmune disease primarily affecting the joints but also the heart and vessels associated with increased cardiovascular mortality. Recent years have produced a wealth of novel insights into the diversity of immune cell types which either propagate or dampen inflammation in atherogenesis. Expansion of this inherent anti-inflammatory component carried by regulator
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Takeshita, Junko, and Joel M. Gelfand. Epidemiology of psoriasis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198737582.003.0002.

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Psoriasis is a common chronic inflammatory disorder of the skin that is associated with multisystem effects. Approximately 125 million people worldwide are affected by psoriasis, nearly one quarter of whom have moderate to severe disease. The majority of patients with psoriasis have a waxing and waning course with variable periods of spontaneous disease improvement or clearance. A rapidly expanding body of epidemiologic literature suggests psoriasis to be associated with a greater comorbid disease burden than patients without psoriasis. In addition to psoriatic arthritis, cardiometabolic disea
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Stolker, Robert Jan, and Felix van Lier. Choice and interpretation of preoperative investigations. Edited by Jonathan G. Hardman. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0041.

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Preoperative risk assessment is one of the most important steps in perioperative management. In the last decades, considerable progress has been achieved. However, as more high-risk procedures are performed in more aged patients, suffering more morbidity, this may lead to an increased risk of adverse outcomes. The goal of preoperative assessment is to identify patients at extreme risk and discuss whether they should be operated on, or undergo an alternative procedure with a lower risk profile, or if conservative treatment should be continued. Furthermore, it gives the opportunity to optimize p
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Zhang, Luxia, and Haiyan Wang. Chronic kidney disease in developing countries. Edited by David J. Goldsmith. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0096_update_001.

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The spread of non-communicable diseases (NCDs) is a barrier to the development of goals including reduction of poverty, health equity, economic stability, and human security. NCDs accounted for 61% of the estimated 58 million deaths and 46% of the global burden of diseases worldwide in 2005. Among NCDs, chronic kidney disease (CKD) is of particular significance. It is recognized that the burden of CKD is not only limited to its impact on demands for renal replacement therapy but has equally major impacts on the health of the overall population. For example, it is now well established that amon
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Harper, Lorraine, and David Jayne. The patient with vasculitis. Edited by Giuseppe Remuzzi. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0160.

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The goals of treatment in renal vasculitis are to stop vasculitic activity and recover renal function. Subsequent strategies are required to prevent vasculitis returning and to address longer-term co-morbidities caused by tissue damage, drug toxicity, and increased cardiovascular and malignancy risk.Cyclophosphamide and high-dose glucocorticoids remain the standard induction therapy with alternative immunosuppressives, such as azathioprine, to prevent relapse. Plasma exchange improves renal recovery in severe presentations. Refractory disease resulting from a failure of induction or remission
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Book chapters on the topic "MACE (major adverse cardiovascular events)"

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Khanfer, Riyad, John Ryan, Howard Aizenstein, et al. "Major Adverse Cardiovascular Event (MACE)." In Encyclopedia of Behavioral Medicine. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_101007.

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Aisah, Iis Siti, Rahma Yuantari, and Linda Rosita. "SGOT Levels in Acute Myocardial Infarction Patients with Mayor Adverse Cardiovascular Events (MACE)." In Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-048-0_34.

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Alay, Ragip Afsin. "The Importance of Hypertension Screening in Children." In Newborn and Childhood Screening Programmes. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053358961.12.

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High blood pressure (BP), more commonly known as hypertension (HT), is one of the significant public health issues in today’s world. The frequency of HT in children was found to be higher in boys than girls and at an M/F ratio of 15-17/7-12%. The most important purpose of detecting HT in childhood is to prevent end organ damage and HT that begins in childhood from affecting morbidity and mortality in adulthood. Two major guidelines for the definition, monitoring, and treatment of hypertension in children are available from the European Society of Hypertension (ESH) and the American Academy of Pediatrics (AAP). In children aged three years and above, ESH requires BP measurement at every health examination, APP requires annual blood pressure measurement, and in children under 3 years of age, blood pressure measurement should be performed in the presence of risk factors for HT. The prevalence of HT in children is increasing, and it appears that if HT in children is not detected and controlled, it can lead to extremely adverse cardiovascular events in middle age and earlier. Every society should create monitoring and screening algorithms by determining risk factors according to life, nutrition and development level.
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Orrapin, Saritphat. "Cardiovascular Complications Related to Lower Limb Revascularization and Drug-Delivering Technology in Peripheral Arterial Disease." In Cardiovascular Diseases [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.107973.

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The cardiovascular complication related to lower limb revascularization is the common cause of mortality in patients with peripheral arterial disease (PAD). The coexisting multisite atherosclerotic vascular disease is increasing risk of major adverse cardiovascular events (MACE). The minimally invasive approach for revascularization, namely, endovascular-first strategy for decreasing risk of intervention is the modern approach. The novel technology of the drug delivering device by paclitaxel, sirolimus, and other antiproliferative drug coated balloon (DCB) and drug eluting stent (DES) to increase the patency of the target artery are trending to use in patients with CLTI. However, the long-term result and safety of a drug delivering device are still controversial. The paclitaxel related to MACE and major adverse limb events (MALE) need to be investigated. The new drug coating balloon, sirolimus demonstrated the excellent short-term result. However, there are some limitations of previous randomized studies and meta-analyses to conclude the best strategy and device to perform the best result for revascularization without increasing risk of MACE and MALE in CLTI patients who candidate for revascularization. This article is summarized the pathophysiology of MACE and MALE in the patients with PAD during revascularization, paclitaxel related cardiovascular complications and sirolimus coated balloon.
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Lorenzer, Lena, Michael Schrempf, Stefanie Jauk, et al. "Harmonization of Electronic Medical Records for Federated Learning: Addressing Challenges in International Healthcare Collaborations." In Studies in Health Technology and Informatics. IOS Press, 2025. https://doi.org/10.3233/shti250175.

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Background: For the development and implementation of a federated learning (FL) model, a clear outcome definition and the harmonization of healthcare data present major challenges. Healthcare institutions use different data representation standards. This variability poses significant challenges for harmonizing data across multiple partners. Objectives: The aim of this paper was to show how we have standardized datasets from three partners from Austria, Germany and Brazil to be used for a FL model for the prediction of major adverse cardiovascular events (MACE). Methods: Each partner extracted healthcare data from their electronic medical record (EMR) system. The mapping of these data was performed using common international standards. Results: The final harmonized dataset consisted of demographic, administration, diagnoses, medication and laboratory data represented with uniform international standards across the partners. Conclusion: This study highlights key challenges of harmonizing healthcare data and provides an example as a solution. In order to confirm reliability of our dataset for predicting MACE using FL, further testing and validation will be performed.
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Michelotti, Erica, Paul M. Ridker, and Raffaele De Caterina. "Antithrombotic strategies in primary cardiovascular prevention." In The ESC Textbook of Thrombosis, edited by Raffaele De Caterina, David J. Moliterno, and Steen Dalby Kristensen. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/med/9780192869227.003.0014.

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Abstract Antithrombotic strategies in primary cardiovascular prevention essentially revolve around the use of aspirin. This chapter provides an update and guidance for the use of aspirin in patients without previous clinical evidence of vascular disease. In contrast to secondary prevention, aspirin in primary prevention is widely debated in part because early trials predated the statin era. furthermore, because prevention of cardiovascular outcomes demonstrated in several trials was counterbalanced by increased risk for bleeding, a net clinical benefit has not clearly been shown in pooled estimates. Using data from the most recent trials, and performing a meta-regression of benefits and risks associated with aspirin use as related to the 10-year risk of major adverse cardiovascular events (MACEs), a tailored approach to aspirin prescription in primary prevention is proposed. In patients aged less than 70 years with optimal risk factor control, individual cardiovascular risk should be carefully evaluated, while also considering bleeding risk and patient preferences. Absolute MACE reduction appears superior to the hazard of haemorrhagic events in patients at intermediate–high cardiovascular risk without a prohibitive bleeding risk, and this category of individuals, as well as those with documented evidence of subclinical carotid, coronary, or peripheral atherosclerotic vascular disease, appear to be a proper target population. Treatment of other cardiovascular risk factors, such as high cholesterol, should, however, be prioritized prior to aspirin administration, and this should be accompanied, especially in the elderly, by the concurrent administration of gastroprotective agents.
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Zheng, Huilin, Syed Waseem Abbas Sherazi, Sang Hyeok Son, and Jong Yun Lee. "A Deep Neural Network Model for the Prediction of Major Adverse Cardiovascular Event Occurrences in Patients with non-ST-Elevation Myocardial Infarction." In Frontiers in Artificial Intelligence and Applications. IOS Press, 2021. http://dx.doi.org/10.3233/faia210172.

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Cardiovascular disease (CVD) is one of the major causes of death all over the world and the mortality rate is higher than other causes. Hence, we propose a novel deep neural network (DNN)-based prediction model for the major adverse cardiovascular event (MACE) occurrences in patients with non-ST-Elevation myocardial infarction (NSTEMI) to improve the prediction accuracy of CVD. The research contents are described as follows. First, for the experiment, we use the Korean Acute Myocardial Infarction Registry (KAMIR-NIH) dataset with 2 years follow-ups and then preprocess the extracted data, such as processing the missing values, solving the imbalance problem, and applying the normalization meth to scale all the datasets in the same range for the experiment. Then we design a DNN-based prognosis model for the occurrences of MACE in NSTEMI patients. Finally, we evaluate the proposed model’s performance and compare it with several applied machine learning algorithms, such as logistic regression, K-Nearest Neighbors, decision tree, and support vector machine. The result shows that the performance of our proposed method outperformed other machine learning-based prediction models.
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Ceren, İmran. "Heart Rate Variability in Myocardial Infarction: A Marker of Autonomic Dysfunction and Clinical Prognosis." In Heart Rate Variability - Current Practices and Clinical Applications [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1011156.

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Myocardial infarction (MI) continues to be a major contributor to global cardiovascular morbidity and mortality, despite advancements in revascularization techniques such as percutaneous coronary intervention (PCI). Recent attention has shifted toward evaluating the autonomic nervous system (ANS) as a key determinant of post-infarction prognosis. Heart rate variability (HRV), a non-invasive marker of autonomic regulation, has emerged as a sensitive tool for assessing cardiac autonomic dysfunction and stratifying cardiovascular risk following MI. Decreased HRV—particularly reductions in time-domain parameters such as standard deviation of normal RR intervals (SDNN) and the root mean square of successive RR interval differences (RMSSD), and altered low-frequency/high-frequency (LF/HF) ratios—has been consistently associated with increased incidence of arrhythmias, major adverse cardiovascular events (MACE), and mortality in both acute and long-term settings. Studies indicate that early reperfusion improves HRV indices, reflecting restored autonomic balance, whereas persistent HRV impairment signals poor prognosis even after successful PCI. Furthermore, advancements in wearable technologies and artificial intelligence have enabled real-time HRV monitoring, expanding its clinical applicability. Incorporating HRV into conventional risk assessment models may enhance the identification of high-risk patients and guide individualized therapeutic strategies. This chapter reviews the physiological underpinnings, measurement methods, clinical relevance, and prognostic value of HRV in the context of MI, with a focus on its potential as an integrative tool in future cardiovascular care.
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Abdel-Hay Mostafa, Tarek, Ahmed Mostafa Abdel-Hameed, and Sameh Abdel-Khalek Ahmed. "Bariatric Surgery: Can It Perform Benefits or Risks?" In Practical Issues in Bariatric Surgery [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1006090.

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Obesity is associated with an increased incidence of heart failure (HF), myocardial infarction (MI), stroke, and death. Weight loss has become a standard recommendation for all patients with cardiovascular disease (CVD) and coexisting obesity. Bariatric surgery has been shown to reduce cardiovascular risk factors significantly; however, whether surgery can reduce major adverse cardiovascular events (MACE), especially in patients with established cardiovascular disease. Bariatric surgery has been associated with a significant reduction in daily insulin requirement and a considerable reduction in body mass index, resulting in long-term results. Furthermore, studies suggest that bariatric surgery for type 1 diabetes results in the improvement of comorbidities related to obesity including hypertension and dyslipidemia. Obesity is thought to be the strongest risk factor for the development of type 2 diabetes. Bariatric surgery has emerged as the single most effective treatment option for type 2 diabetes and obesity. The individuals who underwent bariatric surgery compared with medical/lifestyle intervention had superior glycemic control with less diabetes medication use and higher rates of diabetes remission. Obesity is a pro-inflammatory condition in which some cytokines such as leptin, a pro-inflammatory protein, are elevated and adiponectin, an anti-inflammatory protein, is decreased. In patients undergoing weight reduction surgeries, these hormone levels behave paradoxically. It is not known whether bariatric surgery protects against the development of autoinflammatory or autoimmune conditions; nevertheless, changes occurring in the immune system are incompletely understood. Patients undergoing bariatric surgery show immunological changes which might eventually lead to developing an autoimmune disease.
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Chumpitazi, Corrie E. "Major Adverse Events." In The Pediatric Procedural Sedation Handbook, edited by Cheryl K. Gooden, Lia H. Lowrie, and Benjamin F. Jackson. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190659110.003.0024.

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The incidence of sedation-related adverse events depends on medication characteristics, procedure conditions, and preexisting patient physiologic and psychological conditions. Major adverse sedation-related events represent extreme physiologic change causing significant patient harm that may be long-lasting or permanent, particularly if responded to ineffectively by the sedationist. Large safety studies of pediatric sedation events suggest that events of this type occur very rarely when well-organized, equipped, and trained sedation teams are present. However, sporadic reports of death during pediatric sedation continue to surface, providing significant impetus for effective preparation and training for sedationists. Major adverse sedation-related events discussed here are aspiration, cardiovascular collapse, respiratory failure, and death.
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Conference papers on the topic "MACE (major adverse cardiovascular events)"

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Hoori, Ammar, Juhwan Lee, Robert Gilkeson, Sadeer Al-Kindi, Sanjay Rajagopalan, and David L. Wilson. "Prediction of major adverse cardiovascular events (MACE) from disease progression in low-cost (no-cost) screening CT calcium score images." In Clinical and Biomedical Imaging, edited by Barjor S. Gimi and Andrzej Krol. SPIE, 2025. https://doi.org/10.1117/12.3047388.

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Hu, Tao, Ammar Hoori, Joshua Freeze, et al. "Prediction of major adverse cardiovascular events in Agatston low-risk patients using comprehensive AI analysis of low-cost screening CT calcium score exams." In Computer-Aided Diagnosis, edited by Susan M. Astley and Axel Wismüller. SPIE, 2025. https://doi.org/10.1117/12.3046372.

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Kim, Justin Namuk, Tao Hu, Hao Wu, et al. "Improved C-Index and Interpretability with KAN as Compared to COX: Application to Risk Prediction of Major Adverse Cardiovascular Events from CT Calcium Score." In 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI). IEEE, 2025. https://doi.org/10.1109/isbi60581.2025.10980713.

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Ruiz, Juan I., Bo Zhao, Nicolas Palaskas, et al. "1239 Major adverse cardiovascular events (MACE) in patients with melanoma receiving immune checkpoint inhibitors." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.1239.

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Suarez-Almazor, M., J. Ruiz, B. Zhao, et al. "POS0714 MYOCARDITIS AND MAJOR ADVERSE CARDIOVASCULAR EVENTS (MACE) IN PATIENTS WITH MELANOMA RECEIVING IMMUNE CHECKPOINT INHIBITORS." In EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria. BMJ Publishing Group Ltd and European League Against Rheumatism, 2024. http://dx.doi.org/10.1136/annrheumdis-2024-eular.3230.

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Mok, Chi-Chiu, Kar Li Chan, Ling Yin Ho, and Chi Hung To. "LP-064 Effect of osteoporosis on major adverse cardiovascular events (MACEs) in systemic lupus erythematosus (SLE): a longitudinal study." In The 15th International Congress on Systemic Lupus Erythematosus and The 43rd KCR Annual Scientific Meeting & 17th International Symposium (LUPUS & KCR 2023). Lupus Foundation of America, 2023. http://dx.doi.org/10.1136/lupus-2023-kcr.173.

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Sarker, Sunandita, Yiannis S. Chatzizisis, Srivatsan Kidambi, and Benjamin S. Terry. "Design and Development of a Novel Drug Delivery Catheter for Atherosclerosis." In 2018 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dmd2018-6869.

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Atherosclerosis is a chronic progressive cardiovascular disease that results from plaque formation in the arteries. It is one of the leading causes of death and loss of healthy life in modern world. Atherosclerosis lesions consist of sub-endothelial accumulations of cholesterol and inflammatory cells [1]. However, not all lesions progress to the final stage to cause catastrophic ischemic cardiovascular events [2]. Early identification and treatment of high-risk plaques before they rupture, and precipitate adverse events constitutes a major challenge in cardiology today. Numerous investigations
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Michotte, Naomi, Shane Hanon, Sylvia Verbanck, and Eef Vanderhelst. "Major adverse cardiovascular events in a real-life COPD patient population." In ERS Congress 2024 abstracts. European Respiratory Society, 2024. http://dx.doi.org/10.1183/13993003.congress-2024.pa1760.

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Charles-Schoeman, C., H. Valdez, K. Soma, et al. "SAT0686 Major adverse cardiovascular events: risk factors in patients with ra treated with tofacitinib." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.2434.

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Limdi, Jimmy, C. Janneke van der Woude, Stefan Schreiber, et al. "O35 Thromboembolic and major adverse cardiovascular events among patients in the filgotinib clinical trial programme." In BSG LIVE’23, 19–22 June, ACC Liverpool. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2023. http://dx.doi.org/10.1136/gutjnl-2023-bsg.34.

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Reports on the topic "MACE (major adverse cardiovascular events)"

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Li, Peng, and Junjun Liu. Effect of tumor necrosis factor inhibitors on the risk of adverse cardiovascular events in patients with psoriasis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0090.

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Review question / Objective: Previous studies have indicated a cardioprotective effect of tumor necrosis factor inhibitor (TNFi) therapy in adult patients with psoriasis (Pso). However, most were retrospective studies, and the association between cardiometabolic comorbidities and major adverse cardiovascular events (MACE) has not been validated in randomized controlled trials (RCTs). Condition being studied: Because the available evidence has recently increased, we performed the present updated meta-analysis and meta-regression of cohort studies and RCTs to evaluate whether TNFi therapy can de
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Li, Wenwen, Cuncheng Liu, and Shouqiang Chen. Incidence of major adverse cardiovascular events in the myocardial bridging population: A protocol for systematic review and meta‑analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.5.0021.

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Li, Peng, Na jia, Bing Liu, and Qing He. Effect of cardiac shock wave therapy on adverse cardiovascular event for patients with coronary artery disease: an updated systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.1.0103.

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Review question / Objective: We have previously demonstrated that cardiac shock wave therapy (CSWT) effectively improves myocardial perfusion in patients with coronary artery disease (CAD). In this study, we want to address whether CSWT could decrease the risk of adverse cardiovascular events in CAD patients unsuitable for revascularization. Eligibility criteria: Trials are considered eligible if they meet these criteria: (1) patients included are diagnosed as refractory angina or ischemic heart failure; (2) the study i a randomized controlled trial (RCT) or a prospective cohort study; (3) int
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Ding, Liang-Liang, Mei Qiu, and Xian Zhou. Comparative efficacy of GLP-1 RAs and SGLT2is for prevention of major adverse cardiovascular events in type 2 diabetes: a network meta-analysis. INPLASY - International Platform of Registered Systematic Review Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.4.0177.

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Sabri, Mahshad, Yasaman Hosseini, and Roya Sani. The Additive Prognostic Value of Coronary Artery Calcium Scoring and Single-Photon Emission Computed Tomography (SPECT) on Major Adverse Cardiac Events (MACE): A Systematic Review and Meta-analysis PROTOCOL. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.1.0073.

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