Academic literature on the topic 'Macedonia – History – To 168 B.C'

A precise temporal (and sometimes topographical) scheme is found behind Second Corinthians at three levels: (i) 1–7 (past: Ephesus → Macedonia), 8–9 (present: Macedonia), 10–13 (future: Macedonia → Corinth); (ii) 2.12–7.16 (Troas (2.12–13) → the Hellespont (2.14–7.4) → Macedonia (7.5–16)); (iii) 2.14–7.4. For (i)-(ii), see 1 Thess 1–3 and 2.17–3.10. For (iii), I detail this temporal structure: (a) 3.1–18 → 4.1–6; (b) 4.7–5.10 → 5.11–13; (c) 5.14–6.10 → 6.11–7.4, viz. (a) Paul's initial call and (b) his life in the present and future → his general missionary practice, including to ‘you’, and (c) his now directly addressing ‘you’ with strong paraenesis.

The paper presents research findings with 56 Roma children from Macedonia and Serbia between the ages of 3-6 years. The children’s knowledge of Romani as their mother tongue was assessed with a specially designed test. The test measures the children’s comprehension and production of different types of grammatical knowledge such as wh–questions, wh-complements, passive verbs, possessives, tense, aspect, the ability of the children to learn new nouns and new adjectives, and repetition of sentences. In addition, two pictured narratives about Theory of Mind were given to the children. The hypothesis of the authors was that knowledge of the complex grammatical categories by children will help them to understand better the Theory of Mind stories. The results show that Roma children by the age of 5 know most of the grammatical categories in their mother tongue and most of them understand Theory of Mind.
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The Pangeon granitoids are distinguished into two pétrographie types with sharp contacts: (a) heterogranular, medium- to coarse-grained, hornblende+biotite- bearing porphyritic tonalités and granodiorites (PTG), and, (b) equigranular, medium-grained, biotite±muscovite-bearing granodiorites and granites (MGG). Dark-coloured, medium-grained monzodioritic enclaves occur in PTG rocks. Hornblende 40Ar/39Ar spectra from the PTG rocks yielded cooling ages of 21.7±0.5 Ma to 18.8±0.6 Ma. With the exception one sample, the corresponding hornblende ages from enclaves coincide well with the above ages. The age of 21.7±0.5 Ma is considered as the lower limit for the PTG rocks emplacement. Muscoviteplateau ages of c. 15.7±0.5 Ma and total gas biotite ages of 15.2±0.4 Ma to 13.8±0.5 Ma from the studied rocks, constrain the cooling history of the Pangeon granitoids (with some local variations) in the range 430 - 300Ί C.

Abstract Background Clostridioides difficile (C difficile) infection (CDI) is a major health problem in the United States and despite updated guidelines, the laboratory diagnosis remains vexed. A multistep algorithm is recommended to diagnose CDI that includes antigen, toxin and toxin gene Nucleic Acid Amplification (NAAT) assays. This study was done to assess severity of CDI based on toxin B and NAAT statuses. The other objective was to analyze if antibiotics and PPI/H2B (Proton Pump Inhibitors and H2 blockers) affected severity of CDI. Methods Retrospective analysis of all adult patients admitted to a tertiary medical center with diarrhea and a positive C difficile antigen test from 01/2017- 12/2017. From more than 2000 stool samples submitted to the lab, C diff antigen was positive in 265 patients. 191 were diagnosed with CDI based on the 2-step algorithm. Clinical data was available for 168 patients. Severity of CDI was determined based on published guidelines. Fischer’s exact test was used for statistical analysis. Results The mean age at diagnosis was 55.96. Toxin B was detected in 34% (57/168) patients and Toxin NAAT positive in 66% (111/168) patients. 57% of CDI was health care onset compared to 43% with community onset. 42% (72/168) were classified as severe out of which 40.2% (29) were toxin B positive, and 59.8% (43) were NAAT positive. There were no significant differences in severity of CDI based on toxin B and NAAT status (50.9% vs 38.4%, p=0.14). 46% of cases from community vs 39.6% from hospitals were classified as severe CDI (p=0.415). 72% of cases had antibiotic use in the last 30 days. Use of antibiotics was significantly associated with severe CDI (82% vs 64%, p=0.015). 62.5% (105) patients had history of PPI/H2B use and severity was not significantly associated with its use (p=0.872). Conclusion Our study shows that the presence of toxin did not significantly impact the clinical severity of CDI. The use of antibiotics did not affect the presence of toxin although the total number of CDI cases with previous antibiotic exposure was high. Patients who had recent antibiotic exposure were more likely to have severe clinical presentation. More toxin positive cases were health care onset but the effect was not pronounced. Severity of CDI did not significantly depend on health care onset or on exposure to PPI/H2B. Disclosures Atul Kothari, MD, Ansun Biopharma (Consultant)

AbstractIn this article, the authors discuss the use of power-sharing instruments in the Western Balkans. While the comparison will focus on the use of power-sharing in Bosnia and Herzegovina and Macedonia, there will be occasional references to Kosovo, the third country in the region that displays elements of power-sharing. We argue that the region has been a laboratory of power-sharing instruments, with rather mixed results. While in all three cases, power-sharing was part of a larger strategy of peacebuilding, and was, therefore, successful in ending violent conflict and supporting peaceful conflict resolution, the introduction of power-sharing has also had some negative side effects. We will discuss, in particular, the consequences of complicated political systems, veto rights, as well as far-reaching ethno-territorial autonomy. Furthermore, the article will asses the risk of blockages arising from complex political arrangements and resulting international mediation. A particular focus of the article will be to distinguish between federalism in Bosnia and Herzegovina and alternative forms of autonomy (both territorial and non-territorial) in Macedonia and Kosovo. Rather than suggesting that power-sharing as such has failed in the region, we submit that the experience in the region suggests that: (a) there are no viable alternatives to power-sharing in the selected countries; (b) that different types of power-sharing need to be considered; and (c) that potential membership in the European Union continues to be the only incentive for the efficient implementation and application of power-sharing in the cases discussed.

Winifred Lamb was one of the founding members of the British Institute of Archaeology at Ankara, and a pioneering excavator in Anatolia (Caton-Thompson 1964: 51). Lamb had acquired her excavating skills as a member of the British School at Athens, where she was admitted in 1920 after reading Classics at Newnham College, Cambridge and subsequent war service in Room 40 of the Admiralty (The Times [London] 18 September 1963; Woodward 1963; Barnett 1962–3; Annual Report of the British Institute of Archaeology at Ankara 15 [1963] 2–3; Caton-Thompson 1964; Hood 1998: 70–5; Gill in preparation a, c; see also Ridgway 1996). During the early 1920s she excavated with members of the British School at Mycenae (Lamb 1919–21; Lamb, Wace 1921–3a-e), Sparta (Lamb 1926–7a-b; see also Hood 1998: 59–131) and in Macedonia (Heurtley 1939; Lamb 1940; see also Hood 1998: 144–49). Her interest in prehistory was also reflected in her creation of a prehistoric gallery at the Fitzwilliam Museum in the University of Cambridge, where she had been appointed Honorary Keeper of Greek and Roman antiquities in 1920 (Gill 1999a).

Abstract. Lake Ohrid Basin is a graben structure situated in the Dinarides at the border of the Former Yugoslavian Republic of Macedonia (FYROM) and Albania. It hosts one of the oldest lakes in Europe and is characterized by a basin and range-like geological setting together with the halfgraben basins of Korca, Erseka and Debar. The basin is surrounded by Paleozoic metamorphics in the northeast and north and Mesozoic ultramafic, carbonatic and magmatic rocks in the east, northwest, west and south. Paleocene to Pliocene units are present in the southwest. With the basin development, Neogene sediments from Pliocene to recent deposited in the lows. There are three major deformation phases: (A) NW–SE shortening from Late Cretaceous to Miocene; (B) uplift and diminishing compression during Messinian – Pliocene; (C) vertical uplift and (N)E–(S)W extension from Pliocene to recent led to the basin formation. Neotectonic activity of the study area concentrates on N–S trending normal faults that bound the Ohrid Basin eastwards and westwards. Seismic activity with moderate to strong events is documented during the last 2000 yrs; the seismic hazard level is among the highest in Albania and Macedonia. Activity of the youngest faults is evidenced by earthquake data and field observations. Morphotectonic features like fault scarps, a stepped series of active normal faults, deformed paleosols, a wind gap and fault-related hydrothermal activity are preserved around Lake Ohrid and allow delineating the tectonic history. It is shown that the Lake Ohrid Basin can be characterized as a seismogenic landscape. This paper presents a tectonic history of the Lake Ohrid Basin and describes tectonic features that are preserved in the recent landscape. The analysis of morphotectonic features is used to derive the deformation history. The stratigraphy of the area is summarized and concentrates on the main units.

Aim. A clinical analysis of Burkitt’s lymphoma (BL) in a 4 years-old female child.Materials and methods. A retrospective analysis was conducted for the history, disease’s course, laboratory and instrumental diagnosis and treatment in patient B. with BL, 4 years old.Results. A 4-yo patient was diagnosed with BL spread to bone marrow, CNS, lymph nodes, both kidneys and spleen. Leukocytosis in common blood profile. Elevated lactate dehydrogenase (LDH) and C-reactive protein (CRP) in biochemical blood profile. Neck lymphadenopathy, mediastinum in computed tomography (CT). Splenomegaly. Multifocal lesion of both kidneys. Retroperitoneal lymphadenopathy. Positive clinical dynamics (normalisation of body weight) is observed with background therapy, LDH 335 U/L in biochemical blood profile, reduced multifocal kidney lesion and spleen size in CT.Conclusion. A clinical case of Burkitt’s lymphoma is reported affecting the bone marrow, CNS, lymph nodes, both kidneys and spleen. Intensive polychemotherapy allowed stabilisation of the patient and containment of oncological processes.

This thesis investigates the nature of the relationship between cities and king in the late Classical and Hellenistic Macedonian kingdom. It will consider the cities from two main perspectives: the city as a community, and the city as a settlement. Section 1 re-examines the evidence most commonly used to argue for the Macedonian cities gaining substantial autonomy in this period. It will be argued that this evidence has less to tell us about the political autonomy of the Macedonian cities than their 'social relations' with other Greek communities: Macedonian cities engaged in international exchanges which did not represent any challenge to the authority of the monarch, but which could also be used to represent the relationship between king and city as cooperative. Such latitude was balanced, however, by forceful expressions of royal dominance in other arenas. Section 2 considers the position of the cities within the royal economy, and examines how, as a result of the king's monopolisation of Macedonia's resources, and the fact that the Macedonian elite was more interested in advancing their position at court than acting as civic benefactors, the cities were left economically subordinated to the king. Section 3 uses the increasingly abundant archaeological evidence to consider how royal building programmes served to project royal ideology into the localities. Royal palaces, large-scale urban development, and fortifications created an experience of urban space in Macedonia which emphasised the roles of the monarch as guardian, benefactor, and unifying figure. The picture that emerges is of a kingdom of civic communities which were engaged in meaningful exchanges with their peers outside Macedonia, but which were living in large and impressive urban settlements which stood as monuments to the extent and ubiquity of royal authority. Late-Classical and Hellenistic Macedonia was a kingdom of poleis, but that kingdom was first and foremost a royal space.