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1

Adamkova, Hana, Jaroslav Vicar, Jirina Palasova, Jitka Ulrichova, and Vilim Simanek. "Macleya cordata and Prunella vulgaris in oral hygiene products - their efficacy in the control of gingivitis." Biomedical Papers 148, no. 1 (2004): 103–5. http://dx.doi.org/10.5507/bp.2004.019.

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2

Li, Gong. "Effect of Botanical Insecticide of Macleya Cordata on Physiology and Biochemistry of Cabbage (Brassica oleracea L.)." IERI Procedia 3 (2012): 156–61. http://dx.doi.org/10.1016/j.ieri.2012.09.026.

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3

Chytilová, K., A. Galandáková, J. Zapletalová, and J. Pazdera. "Antimicrobial and Anti-Inflammatory Activities of Extract from Macleya cordata (Willd) R. Br. in the Treatment of "Dry Socket"." Česká stomatologie/Praktické zubní lékařství 113, no. 2 (2013): 52–59. http://dx.doi.org/10.51479/cspzl.2013.013.

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4

Chytilová, K., A. Galandáková, J. Zapletalová, and J. Pazdera. "Antimicrobial and Anti-Inflammatory Activities of Extract from Macleya cordata (Willd) R. Br. in the Treatment of "Dry Socket"." Česká stomatologie/Praktické zubní lékařství 113, no. 2 (2013): 52–59. http://dx.doi.org/10.51479/cspzl.2013.013.

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5

Li, Gong. "Effect of Botanical Insecticide of Macleya cordata on Physiology and Biochemistry of Cabbage (Brassica oleracea L.)." Research Journal of Applied Sciences, Engineering and Technology 6, no. 3 (2013): 492–95. http://dx.doi.org/10.19026/rjaset.6.4107.

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6

Zhukova, I. O., A. A. Molchanov, I. O. Kostiuk, O. M. Bobrytska, N. I. Lonhus, and I. A. Ionov. "The investigation of the influence which is done as a result of macleaya cordata and biologically active additives on the carbohydrate metabolism in pigs." Scientific Messenger of LNU of Veterinary Medicine and Biotechnology 21, no. 93 (2019): 137–42. http://dx.doi.org/10.32718/nvlvet9324.

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Pork production plays a significant role in meat balance of Ukraine. High productivity of pigs is accompanied with increased intensity of metabolic processes and intense functional activity of all organs and systems, which requires additional support. To grow a healthy livestock, it is necessary to use preparations and biologically active forage plant additives that help a body to realize productive qualities, fight against various pathogens, but do not harm the animal body and are safe in the production of meat products for human nutrition. The influence of phytobiotic of the cardiac macleaya
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7

Rogelio, Altamira Santiago, García López Juan Carlos, Ballesteros Rodea Gilberto, et al. "Macleaya cordata Extract as an Ethnoveterinary Alternative for Broilers Challenged with Salmonella typhimurium." Journal of Natural Products and Resources 7, no. 1 (2021): 265–66. http://dx.doi.org/10.30799/jnpr.094.21070101.

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In order to evaluate the ethnoveterinary effect of Macleaya cordata extract on bacteria colony forming units (CFU) in different organs of gastrointestinal tract and productive parameters of broilers challenged with Salmonella typhimurium, eighty one day old Cobb broilers were randomly assigned either to a diet without additive or with additive at 50 g/ton during 21 days. The count of CFU of Salmonella typhimurium in crop, gizzard, and duodenum, at 21 days, showed broilers that received the Macleaya cordata extract had a reduction. The broilers also had higher final body weight, total gain, ave
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8

Park, M. J., S. E. Cho, M. Piątek, and H. D. Shin. "First Report of Powdery Mildew Caused by Erysiphe macleayae on Macleaya microcarpa in Poland." Plant Disease 96, no. 9 (2012): 1376. http://dx.doi.org/10.1094/pdis-03-12-0244-pdn.

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Macleaya microcarpa (Maxim.) Fedde, also known as smallfruit plume poppy, is a perennial herb belonging to the family Papaveraceae. The plant, together with the better-known species M. cordata (Willd.) R. Br., is native to central China and is now planted worldwide for medicinal purposes. In October 2008 and August 2009, dozens of smallfruit plume poppy planted in the Kraków Botanical Garden, Poland, were found to be severely infected with a powdery mildew. White colonies with abundant sporulation developed on both sides of leaves and young stems, forming circular to irregular patches. Infecti
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9

Sai, Chun-Mei, Da-Hong Li, Sheng-Ge Li, et al. "Racemic alkaloids from Macleaya cordata: structural elucidation, chiral resolution, and cytotoxic, antibacterial activities." RSC Advances 6, no. 47 (2016): 41173–80. http://dx.doi.org/10.1039/c6ra05423d.

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10

Sai, Chun-Mei, Ning-Bo Qin, Cui-Cui Jia, et al. "Macleayine, a new alkaloid from Macleaya cordata." Chinese Chemical Letters 27, no. 11 (2016): 1717–20. http://dx.doi.org/10.1016/j.cclet.2016.06.017.

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11

Li, Y., H. Li, Q. Chu, F. Xu, T. Liang, and B. Zhou. "Macleaya cordata extracts suppressed the increase of a part of antibiotic resistance genes in fecal microorganism of weaned pigs." Canadian Journal of Animal Science 98, no. 4 (2018): 884–87. http://dx.doi.org/10.1139/cjas-2017-0200.

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This study was designed to evaluate the effects of Macleaya cordata extracts (Chinese herbal medicine extracts) and antibiotics combination with chlortetracycline (CTC) on the antibiotic resistance genes in fecal microorganism. Compared with the group without antibiotics, the relative abundances of all six tetracycline resistance genes were increased after 75 mg kg−1 CTC supplementation. Interestingly, M. cordata extracts in feed suppressed the increase of a part of tetracycline resistance genes in fecal microorganism of weaned pigs.
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12

Psotova, J., R. Vecera, A. Zdarilova, et al. "Safety assessment of sanguiritrin, alkaloid fraction of Macleaya cordata, in rats." Veterinární Medicína 51, No. 4 (2012): 145–55. http://dx.doi.org/10.17221/5534-vetmed.

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The subchronic safety of sanguiritrin, a mixture of sanguinarine (SA) and chelerythrine (CHE) quaternary benzo[c]phenanthridine alkaloids (QBA), obtained from Macleaya cordata was assessed. Rats were fed a diet containing 120 ppm sanguiritrin (100 ppm QBA) for 109 days. The feed consumption and the animal weight were monitored. The content of QBA in selected tissues and plasma was determined using HPLC. It was evidenced that 2% of QBA were absorbed through the GIT while 98% were excreted in the feces. In plasma, bilirubin, urea, creatinine, glomerular filtration, AST, ALT, GMT, ALP an
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13

Kosina, Pavel, Jana Gregorova, Jiri Gruz, et al. "Phytochemical and antimicrobial characterization of Macleaya cordata herb." Fitoterapia 81, no. 8 (2010): 1006–12. http://dx.doi.org/10.1016/j.fitote.2010.06.020.

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14

Khin, Manead, Alan M. Jones, Nadja B. Cech, and Lindsay K. Caesar. "Phytochemical Analysis and Antimicrobial Efficacy of Macleaya cordata against Extensively Drug-Resistant Staphylococcus aureus." Natural Product Communications 13, no. 11 (2018): 1934578X1801301. http://dx.doi.org/10.1177/1934578x1801301117.

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The antibiotic resistant threat is continuing to grow, due in part to the overuse of antibiotics in livestock feed. Many nations in Europe have banned the use of antibiotics in feed, leading to higher rates of infection in livestock animals and reduced productivity for the food market. Increasingly, researchers are looking into the efficacy of phytopreparations to replace antibiotics in feed, allowing for increased animal health without the development of resistance. Macleaya cordata, or Chinese plume poppy, shows promise as a food additive. To evaluate the antimicrobial efficacy of this plant
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15

FENG, Feng, Feng-Zhi YE, Cai-Lian LI, Wen-Yuan LIU, and Ning XIE. "Two new benzo phenanthridine isoquinoline alkaloids from Macleaya cordata." Chinese Journal of Natural Medicines 10, no. 5 (2012): 378–82. http://dx.doi.org/10.1016/s1875-5364(12)60076-4.

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16

Sai, Chun-Mei, Da-Hong Li, Chun-Mei Xue, et al. "Two Pairs of Enantiomeric Alkaloid Dimers from Macleaya cordata." Organic Letters 17, no. 16 (2015): 4102–5. http://dx.doi.org/10.1021/acs.orglett.5b02044.

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17

Stiborova, Marie, Jitka Vostalova, Adela Zdarilova, et al. "MACLEAYA CORDATA EXTRACT AND SANGROVIT GENOTOXICITY. ASSESSMENT IN VIVO." Biomedical Papers 152, no. 1 (2008): 35–39. http://dx.doi.org/10.5507/bp.2008.005.

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18

Liu, Hao, Jihua Wang, Jianglin Zhao, et al. "Isoquinoline Alkaloids from Macleaya cordata Active against Plant Microbial Pathogens." Natural Product Communications 4, no. 11 (2009): 1934578X0900401. http://dx.doi.org/10.1177/1934578x0900401120.

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Bioassay-guided fractionation of the crude extract of the whole plant of Macleaya cordata R. Br. led to the isolation of four alkaloids, which were identified as sanguinarine (1), chelerythrine (2), protopine (3) and α-allocryptopine (4) on the basis of their physicochemical and spectrometric data. Compounds 1 and 2 demonstrated a significant antifungal activity against the six test fungi with median inhibitory concentrations (IC50) ranging from 0.47 to 6.13 μg/mL. Compound 1 was the most effective with an IC50 of 0.47 μg/mL on Rhizoctonia solani. Furthermore, compounds 1 and 2 also demonstrat
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19

Petruczynik, Anna, Tomasz Plech, Tomasz Tuzimski, et al. "Determination of Selected Isoquinoline Alkaloids from Mahonia aquifolia; Meconopsis cambrica; Corydalis lutea; Dicentra spectabilis; Fumaria officinalis; Macleaya cordata Extracts by HPLC-DAD and Comparison of Their Cytotoxic Activity." Toxins 11, no. 10 (2019): 575. http://dx.doi.org/10.3390/toxins11100575.

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Alkaloids have protective functions for plants and can play an important role in living organisms. Alkaloids may have a wide range of pharmacological activities. Many of them have cytotoxic activity. Nowadays, cancer has become a serious public health problem. Searching for effective drugs with anticancer activity is one of the most significant challenges of modern scientific research. The aim of this study was the investigation of cytotoxic activity of extracts obtained from Corydalis lutea root and herb, Dicentra spectabilis root and herb, Fumaria officinalis, Macleaya cordata leaves and her
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20

Chytilová, K., A. Galandáková, J. Pazdera, A. Svobodová, and V. Šimánek. "Effect of Macleaya Cordata (Willd) R.Br. Extract on Expression of Inflammatory Markers and Oxidative Stress in Gingival Fibroblasts." Česká stomatologie/Praktické zubní lékařství 112, no. 2 (2012): 47–56. http://dx.doi.org/10.51479/cspzl.2012.008.

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21

Chytilová, K., A. Galandáková, J. Pazdera, A. Svobodová, and V. Šimánek. "Effect of Macleaya Cordata (Willd) R.Br. Extract on Expression of Inflammatory Markers and Oxidative Stress in Gingival Fibroblasts." Česká stomatologie/Praktické zubní lékařství 112, no. 2 (2012): 47–56. http://dx.doi.org/10.51479/cspzl.2012.008.

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22

Kui, Wang, Luo Chao, Liu Hao, Xu Jianmei, Sun Weibo, and Zhou Ligang. "Nematicidal activity of the alkaloids from Macleaya cordata against certain nematodes." African Journal of Agricultural Research 7, no. 44 (2012): 5925–29. http://dx.doi.org/10.5897/ajar11.1940.

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23

Wang, Xue-Jun, Chang-Li Min, Mei Ge, and Rui-Hua Zuo. "An Endophytic Sanguinarine-Producing Fungus from Macleaya cordata, Fusarium proliferatum BLH51." Current Microbiology 68, no. 3 (2013): 336–41. http://dx.doi.org/10.1007/s00284-013-0482-7.

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24

Lin, Li, Yan-Chun Liu, Jia-Lu Huang, et al. "Medicinal plants of the genusMacleaya(Macleaya cordata,Macleaya microcarpa): A review of their phytochemistry, pharmacology, and toxicology." Phytotherapy Research 32, no. 1 (2017): 19–48. http://dx.doi.org/10.1002/ptr.5952.

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25

Zeng, Jianguo, Yisong Liu, Wei Liu, et al. "Integration of Transcriptome, Proteome and Metabolism Data Reveals the Alkaloids Biosynthesis in Macleaya cordata and Macleaya microcarpa." PLoS ONE 8, no. 1 (2013): e53409. http://dx.doi.org/10.1371/journal.pone.0053409.

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26

Paredes, Manuel, Víctor Paico, José Mantilla, and Arif Mustafa. "Extracto de Macleaya cordata como uso alternativo a la bacitracina en lechones." Revista de Investigación de Agroproducción Sustentable 4, no. 2 (2020): 23. http://dx.doi.org/10.25127/aps.20202.550.

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<p>Veintisiete lechones Yorkshire x Duroc de veintiocho días de edad fueron alimentados con una de las tres dietas experimentales que consistían en una dieta basal (DB), la dieta basal suplementada con 50 mg de extracto de <em>Macleaya cordata</em> por kg de dieta (DB-EMC) y la dieta basal suplementada con 50 g de bacitracina de zinc por kg de dieta (DB-B) durante un período de cinco semanas. En comparación de los animales que recibieron las dietas suplementadas con extracto de <em>Macleaya cordata</em> (EMC) y bacitracina, los cerdos alimentados con la dieta basa
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27

Huang, Peng, Min Xu, Liqiong Xia, et al. "Establishment of an efficient Agrobacterium -mediated genetic transformation method in Macleaya cordata." Scientia Horticulturae 226 (December 2017): 302–6. http://dx.doi.org/10.1016/j.scienta.2017.09.004.

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28

Qing, Zhi-Xing, Yu-Qin Xu, Peng Yang, Kun Yu, Pi Cheng, and Jian-Guo Zeng. "Mass spectrometry-guided isolation of two new benzoquinoline alkaloids from Macleaya cordata." Natural Product Research 30, no. 9 (2015): 1030–35. http://dx.doi.org/10.1080/14786419.2015.1101695.

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29

Qing, Zhi-Xing, Peng Yang, Kun Yu, et al. "Mass spectrometry-guided isolation of two new dihydrobenzophenanthridine alkaloids from Macleaya cordata." Natural Product Research 31, no. 14 (2017): 1633–39. http://dx.doi.org/10.1080/14786419.2017.1285300.

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30

杨, 家强. "Diagnosis and Treatment of Ventricular Electrical Storm Caused by Macleaya cordata Intoxication." Asian Case Reports in Vascular Medicine 07, no. 02 (2019): 36–40. http://dx.doi.org/10.12677/acrvm.2019.72006.

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31

Yu, Linlan, Li Zhou, Wei Liu, et al. "Identification of drought resistant miRNA in Macleaya cordata by high-throughput sequencing." Archives of Biochemistry and Biophysics 684 (May 2020): 108300. http://dx.doi.org/10.1016/j.abb.2020.108300.

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32

Wang, Jie, Xiao Wang, Jike Li, et al. "Several newly discovered Mo-enriched plants with a focus on Macleaya cordata." Environmental Science and Pollution Research 25, no. 26 (2018): 26493–503. http://dx.doi.org/10.1007/s11356-018-2641-7.

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33

Xue, G. D., S. B. Wu, M. Choct, A. Pastor, T. Steiner, and R. A. Swick. "Impact of a Macleaya cordata-derived alkaloid extract on necrotic enteritis in broilers." Poultry Science 96, no. 10 (2017): 3581–85. http://dx.doi.org/10.3382/ps/pex164.

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34

Li, Bin, Jin-qiu Zhang, Xian-gan Han, Zheng-lei Wang, Yuan-yuan Xu, and Jin-feng Miao. "Macleaya cordata helps improve the growth-promoting effect of chlortetracycline on broiler chickens." Journal of Zhejiang University-SCIENCE B 19, no. 10 (2018): 776–84. http://dx.doi.org/10.1631/jzus.b1700435.

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35

Matulka, Ray A., Sophie von Alvenslebe, and Mauro Morlacchin. "Tolerance and Residue Study for Standardized Macleaya cordata Extract Added to Chicken Feed." International Journal of Poultry Science 13, no. 7 (2014): 368–73. http://dx.doi.org/10.3923/ijps.2014.368.373.

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36

Baek, Mi-Young, Hee-Jung Park, Gi-Min Kim, et al. "Insecticidal alkaloids from the seeds of Macleaya cordata on cotton aphid (Aphis gossypii)." Journal of the Korean Society for Applied Biological Chemistry 56, no. 2 (2013): 135–40. http://dx.doi.org/10.1007/s13765-013-3013-0.

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37

Yu, Kun, Yi Peng, Zhixing Qing, et al. "Two pairs of new dihydrobenzophenanthridine alkaloid isolated from the root of Macleaya cordata." Phytochemistry Letters 22 (December 2017): 9–12. http://dx.doi.org/10.1016/j.phytol.2017.08.002.

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38

Yu, Linlan, Li Zhou, Wei Liu, et al. "First Report of Fusarium fujikuroi Causing Black Rot of Macleaya cordata in China." Plant Disease 103, no. 9 (2019): 2476. http://dx.doi.org/10.1094/pdis-01-19-0188-pdn.

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39

Qing, Zhi-Xing, Xiu-Bin Liu, Hui-Min Wu, Pi Cheng, Yi-Song Liu, and Jian-Guo Zeng. "An improved separation method for classification of Macleaya cordata from different geographical origins." Analytical Methods 7, no. 5 (2015): 1866–71. http://dx.doi.org/10.1039/c4ay02600d.

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In this study, an improved separation method for the metabolomic study of polar and basic secondary metabolites by high-performance liquid chromatography-quadrupole-time-of-flight-mass spectrometry (HPLC-Q-TOF-MS) using an “Xcharge C18” column has been developed.
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40

Zeng, Ze, Ping Sheng, Huaqi Zhang, et al. "The effect of Macleaya cordata extract on in vitro ruminal fermentation and methanogenesis." Food Science & Nutrition 9, no. 8 (2021): 4561–67. http://dx.doi.org/10.1002/fsn3.2436.

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41

Zhukova, I. O., N. O. Bazdyreva та N. I. Longus. "Вплив маклеї серцевидної на стан системи антиоксидантного захисту організму качок за дегельмінтизації фенбендазолом". Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 19, № 73 (2017): 40–45. http://dx.doi.org/10.15421/nvlvet7309.

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The use of biological products ecologically safe for human and animals is the key to improve the quality of life. The replacement of synthetic antibiotics, hormone stimulants and other hazardous chemical drugs by natural substances of plant origin is an effective step to decrease gastrointestinal disorders and to improve the indices of growth and development of various species of animals. The beneficial effect of the above drugs can be explained by the potential of these substances to maintain beneficial microflora of gastrointestinal tract that protects the animal from pathogenic bacteria and
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42

Zhukova, I. O., N. O. Bazdyryeva, and I. O. Kostyuk. "Morphological and biochemical indicators of geese blood by deworming with brovermektin and by adding to the ration macleaya cordata and vegetable sources of bioflavonoids." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 20, no. 83 (2018): 396–400. http://dx.doi.org/10.15421/nvlvet8377.

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One of the problems connected with the process of geese growing up is infectious diseases (infectious and parasitic), which hurt the fowls’ organisms and are in for economic lesion. As some helminths (caryocolum tetrameris and echinuria uncinata) have transitional carriers who live in the aquatic environment (water flea, freshwater shrimp and asellus aquaticus) and can infect geese in the process of grazing. Another problem of antiparasitic actions is parasits’ resistance to the majority of preparations. The perspectives of this field is determined by the usage of antihelminthics of broad spec
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43

TOPRAK, NESE NURAY. "Effects of Macleaya cordata extract supplementation in milk on growth performance, some biochemical parameters and a number of selected bacterial groups of the recto-anal microbiota of calves." Medycyna Weterynaryjna 76, no. 08 (2020): 6438–2020. http://dx.doi.org/10.21521/mw.6438.

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The objective of this study was to investigate the effects of milk Macleaya cordata extract supplementation on the weight gain, feed intake, serum total protein (TP), albumin, globulin, IgG, blood urea nitrogen (BUN), triglyceride (TG), beta-hydroxy butyric acid (BHBA) levels, alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT) levels and total aerobic, lactobacillus and coliform bacterial counts of recto-anal swabs in Simmental calves. The feeding study was carried out using 20 (n = 10) 4-day-old Simmental calves (average birth weight 45.55 ± 1.53 kg)
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44

Kurkin, Vladimir A., Elena V. Avdeeva, Olga E. Pravdivtseva, et al. "Scientific evidence for efficiency of medicinal plants in otorhinolaryngology." Science and Innovations in Medicine 6, no. 2 (2021): 54–59. http://dx.doi.org/10.35693/2500-1388-2021-6-2-54-59.

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Objectives to provide scientific evidence for rational use of herbal medicines in otorhinolaryngological practice.
 Material and methods. The study included the following plants: Eucalyptus viminalis leaves, Monarda fistulosa herbs, Melissa officinalis herbs, Echinacea purpurea herbs, Calendula officinalis flowers, rhizomes of Rhodiola rosea, rhizomes of Eleutherococcus senticosus, Glycyrrhiza glabra roots, Macleaya microcarpa herbs, Macleaya cordata herbs, Plantago major leaves, Origanum vulgare herbs, Thymus serpyllum herbs. Phenylpropanoids, flavonoids, euglobals, monoterpene phenols,
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45

Liu, Xiubin, Yisong Liu, Peng Huang, et al. "The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism." Molecular Plant 10, no. 7 (2017): 975–89. http://dx.doi.org/10.1016/j.molp.2017.05.007.

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46

Ke, Wenshan, Xiong Lin, Zhengshen Yu, Qiqiang Sun, and Qian Zhang. "Molluscicidal activity and physiological toxicity of Macleaya cordata alkaloids components on snail Oncomelania hupensis." Pesticide Biochemistry and Physiology 143 (November 2017): 111–15. http://dx.doi.org/10.1016/j.pestbp.2017.08.016.

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47

You, J. M., H. Liu, and B. J. Huang. "First Report of Southern Blight Caused by Sclerotium rolfsii on Macleaya cordata in China." Plant Disease 100, no. 2 (2016): 530. http://dx.doi.org/10.1094/pdis-06-15-0675-pdn.

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48

Zhou, Li, Peng Huang, Linlan Yu, and Jianguo Zeng. "First report of root rot caused by Fusarium oxysporum on Macleaya cordata in China." Journal of Plant Pathology 102, no. 1 (2019): 191–92. http://dx.doi.org/10.1007/s42161-019-00382-8.

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49

Zhang, Qi, Zhenyan Zhang, Shuyidan Zhou, et al. "Macleaya cordata extract, an antibiotic alternative, does not contribute to antibiotic resistance gene dissemination." Journal of Hazardous Materials 412 (June 2021): 125272. http://dx.doi.org/10.1016/j.jhazmat.2021.125272.

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50

Och, Anna, Katarzyna Szewczyk, Łukasz Pecio, Anna Stochmal, Daniel Załuski, and Anna Bogucka-Kocka. "UPLC-MS/MS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/9369872.

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Cancer is one of the most occurring diseases in developed and developing countries. Plant-based compounds are still researched for their anticancer activity and for their quantity in plants. Therefore, the modern chromatographic methods are applied to quantify them in plants, for example, UPLC-MS/MS (ultraperformance liquid chromatography tandem mass spectrometry). Therefore, the aim of the present study was to evaluate the content of sanguinarine, berberine, protopine, and chelidonine in Dicentra spectabilis (L.) Lem., Fumaria officinalis L., Glaucium flavum Crantz, Corydalis cava L., Berberi
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