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1

Srinivas, G., D.V. Ramanjaneyulu, E. Muralinath, et al. "An Essential Parameters of Zika Virus Include Etiology, Epidemiology, Patho Physiology, Diagnosis, Differential Diagnosis, Treatment, Outcomes and Conclusion." Research & Reviews: Journal of Nursing in Women's Health and Midwifery 1, no. 2 (2025): 14–21. https://doi.org/10.5281/zenodo.15542127.

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<em>The Zika virus is a single-stranded RNA virus that belongs to the Flavivirus genus and family. The majority of persons have mild, self-limiting Zika virus infections. This exercise describes how to assess and treat the Zika virus and emphasizes the need of the interprofessional team, especially in identifying and treating this illness.</em>
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Göksu, Zeynep Kübra, and Ali Karayağmurlu. "Successful management of lamotrigine-associated skin rashes in an adolescent girl with autism and bipolar disorder." Cukurova Medical Journal 49, no. 4 (2024): 1104–6. https://doi.org/10.17826/cumj.1396271.

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Lamotrigine, an antiepileptic class drug, is an agent that can be used as a mood stabilizer in children and adolescents and skin rashes as a side effect are seen. Rarely, Stevens Johnson Syndrome may develop with skin rashes that may be mortal accompanied by systemic symptoms. In this paper, lamotrigine was started as a mood stabilizer in addition to the current olanzapine treatment in an 18 years old adolescent girl with autism spectrum disorderand bipolar disorder type 2. After the dose was increased, erythematous acneiform rash developed on the 10th day. Then, lamotrigine was discontinued a
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Witt, Olaf, Susan N. Chi, Hyoung Jin Kang, et al. "Post hoc analysis of rashes reported in patients (pts) with BRAF -altered relapsed/refractory (r/r) pediatric low-grade glioma (pLGG) treated with the type II RAF inhibitor tovorafenib in FIREFLY-1." Journal of Clinical Oncology 43, no. 16_suppl (2025): 10037. https://doi.org/10.1200/jco.2025.43.16_suppl.10037.

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10037 Background: Targeted therapies have become a mainstay in the treatment of pLGG. While effective, toxicities, including cutaneous adverse events (AEs), are common. Tovorafenib received accelerated FDA approval in April 2024 for the treatment of BRAF -altered r/r pLGG in pts ≥6 months of age based on FIREFLY-1 (NCT04775485) trial results. Maculopapular rash, dermatitis acneiform, and erythematous rash were the most commonly reported rashes (Kilburn LB, et al. Nat. Med. 2024). An update on the incidence, recurrence, and resolution of rash AEs in pts who received tovorafenib in FIREFLY-1 is
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4

Haan, P., D. P. Bruynzkel, and W. G. Ketel. "Onset of Penicillin Rashes: Relation between Type of Penicillin Administered and Type of Immune Reactivity." Allergy 41, no. 1 (1986): 75–78. http://dx.doi.org/10.1111/j.1398-9995.1986.tb00279.x.

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Gaydina, Tatiana A., Olga I. Patsap, and Raisa T. Tairova. "Annular elastolytic giant cell granuloma in a patient with Ehlers–Danlos syndrome." Vestnik dermatologii i venerologii 98, no. 4 (2022): 85–94. http://dx.doi.org/10.25208/vdv1338.

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The article presents a clinical case of annular elastolytic giant cell granuloma (AEGCG) in a young patient with a vascular type of EhlersDanlos syndrome. The first clinical manifestations of AEGCG appeared on the skin in the right subclavian area about two years ago. Subsequently, new rashes appeared on the skin of the upper and lower extremities up to four new foci per year. The patient underwent ambulatory therapy as a solution of calcium gluconate 10% 5.0 ml No 10 i/v in every other day; a solution of chloropyramine hydrochloride 1.0 ml No 10 i/m every other day; betamethasone + salicylic
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Yale, Liu, Wang Hao, Taylor Mark, et al. "scRNA-seq for chronic inflammatory skin rashes." Science Immunol 7, no. 70 (2022): abl9165. https://doi.org/10.5281/zenodo.6471748.

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In our manuscript, we utilized scRNA-seq libraries we generated (Classification of human chronic inflammatory skin disease based on single-cell immune profiling (science.org)), samples from the Reynolds et al dataset (&nbsp;Developmental cell programs are co-opted in inflammatory skin disease (science.org)), and samples from the Bangert et al dataset (Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4R&alpha; blockade (science.org)).&nbsp;&nbsp; &nbsp; An integrated object encompassing samples from these three datasets (<str
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7

Shahzad, Naiyer. "Monitoring of adverse drug reactions in individuals with type 2 diabetes mellitus receiving oral hypoglycemic agents." Journal of Umm Al-Qura University for Medical Sciences 9, no. 1 (2023): 37–44. http://dx.doi.org/10.54940/ms84792341.

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Background: This study intends to ascertain the prevalence and overall burden of various adverse drug reactions (ADRs) driven by oral antidiabetics for treating type II diabetes mellitus (T2DM) in India. Methods: Patients with T2DM taking oral antidiabetic medications participated in prospective observational research. Data collection used the pretested format by the Indian pharmacovigilance program to record the history of drugs suspected to be responsible for ADRs. The causality evaluation is according to the guidelines of the Uppsala Monitoring Center and the World Health Organization. Resu
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8

Hum, R. M., J. B. Lilleker, J. Lamb, et al. "POS1221 CLINICAL FEATURES OF PATIENTS WITH ANTI-SYNTHETASE SYNDROME AND DERMATOMYOSITIS-ASSOCIATED SKIN MANIFESTATIONS: RESULTS FROM THE MYONET REGISTRY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 945.2–946. http://dx.doi.org/10.1136/annrheumdis-2023-eular.79.

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BackgroundUp to 28% of patients with anti-synthetase syndrome (AsyS) have dermatomyositis (DM)-type rashes. However, it is not clear whether ASyS patients with DM-type rashes should be treated similarly to patients with DM or classified as DM in a clinical trial setting. Furthermore, it is not known if presence of DM-type rashes confers an increased risk of DM-specific extramuscular manifestations, such as malignancy.ObjectivesTo compare clinical characteristics, including the frequency of cutaneous, extramuscular features, and malignancy, between adults with ASyS and DM.MethodsUsing data from
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9

Kinaciyan, Tamar, Nergis Ghanim, Franziska Roth-Walter, et al. "376 Epidemiology of Immediate Type Adverse Drug Reactions and Rashes Elicited by Nsaid." World Allergy Organization Journal 5 (February 2012): S120. http://dx.doi.org/10.1097/01.wox.0000412139.96672.33.

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10

Era, Nikhil, Shatavisa Mukherjee, Bibhuti Saha, and Santanu Kumar Tripathi. "Monitoring cutaneous adverse drug reactions in patients on TDF+3TC+EFV: a single centre experience." International Journal of Basic & Clinical Pharmacology 6, no. 6 (2017): 1467. http://dx.doi.org/10.18203/2319-2003.ijbcp20172243.

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Background: HIV-infected patients initiating antiretroviral therapy may manifest a wide variety of ADRs ranging from trivial manifestation, such as rashes, pigmentation, to severe life‑threatening reactions, such as Steven–Johnson syndrome, toxic epidermal necrolysis. The present study thus monitored cutaneous adverse drug reactions in patients on first line antiretroviral regimen comprising of tenofovir disoproxil fumerate, lamivudine and efavirenz as a three drug-combination.Methods: A prospective observational clinical study was carried out for a period of one year among PLHIV receiving TDF
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11

Janeš, Ivona, and Marta Navratil. "Case Report: True Drug Sensitization to Co-amoxiclav During Acute Infectious Mononucleosis." Paediatria Croatica 66, no. 1-2 (2022): 34–37. http://dx.doi.org/10.13112/pc.367.

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Skin reactions following antibiotic administration amidst acute infectious mononucleosis (IM) were long thought to be exclusively atransient hypersensitivity reaction of the immune system, and further allergological testing was rarely conducted. This paper presents the case of a 19-month-old boy who developed a delayed-type hypersensitivity reaction to co-amoxiclav during acute IM. Thecase serves as a reminder that any new onset of rashes following antibiotic treatment should undergo detailed allergological testinguntil proven otherwise.
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Hussaini, Syeda Zaineb Humaira, Faiza Aftab, Nisma Siddiqi, Syed Ishtiaq Ahmed, and Syed Abdul Rehman. "Oxaliplatin Induced Severe Hypoxemia, Chills and Hypersensitivity Reaction." Journal of Drug Delivery and Therapeutics 12, no. 1 (2022): 39–41. http://dx.doi.org/10.22270/jddt.v12i1.5278.

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Hypersensitivity reactions to platinum containing compounds are well described and potentially life threatening. The hypersensitivity reactions can occur either during, or shortly after the infusion of drug. The incidence increases with increase in the number of chemotherapy cycles. Hypersensitivity reactions can vary from mild reactions like rashes to severe reactions, which include laryngospasm, tachycardia, hypotension or hypertension. The combination of 5-flurouracil, leucovarin and oxaliplatin has been used in several studies to increase survival rates and reduce the risk of disease progr
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Ali, Md Asif, Mohammad Imnul Islam, and Shahana Akhtar Rahman. "CANDLE Syndrome: Case Report of a Rare Type of Auto- Inflammatory Disease." Bangladesh Journal of Child Health 44, no. 3 (2021): 174–77. http://dx.doi.org/10.3329/bjch.v44i3.52711.

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CANDLE syndrome (chronic atypical neutophilic dermatosis with lipodystrophy and elevated temperature) is an autoinflammatory disease/syndrome characterized by recurrent fever, skin lesions, and multisystem inflammatory manifestations. Most of the patients have shown mutation in PSMB8 gene. Here, we report a 9-year-old girl with recurrent fever, atypical facies, widespread skin lesions, generalized lymphadenopathy, hepato-splenomegaly, lipodystrophy, and failure to thrive. Considering the clinical features and laboratory investigations including skin biopsy findings, diagnosis was consistent wi
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14

Dr, Qadeer Shabir Dr Syeda Qandeel Zahra Dr Muhammad Mubashir Jamil Dr Gulnaz Tabassum Dr Kifayat Ullah Karim Dr Sajid Mehmood Dr Shaheer Shah Dr Abdul Basit Khan. "PREVALENCE AND MANAGEMENT OF SCABIES IN INTERNATIONAL STUDENTS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 06 (2019): 12772–77. https://doi.org/10.5281/zenodo.3252922.

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<strong><em>Objective: </em></strong><em>The main purpose of study is to evaluate the cause / etiology of scabies. It was expected that this study would be helpful in identifying the cause of scabies, management and prevention of scabies in international students.&nbsp; Research was descriptive in nature. In research, we used tabulation method for interpretation and objectively exalted every possibility to find out accuracy in getting result to maximum extent. </em> <strong><em>Methods: </em></strong><em>We used survey method for collection of data from selected population by questioner method
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15

Martini, Lorenzo. "The skin is the best alarm bell for recognizing the presence of the Omicron variant in younger asymptomatic patients." Our Dermatology Online 13, no. 3 (2022): 319–20. http://dx.doi.org/10.7241/ourd.20223.22.

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Sir, Since the real symptoms of having contracted COVID-19 and its variants or subvariants are generally cough, a runny nose, fever, and loss of taste, and since these alarms are not evident in asymptomatic patients infected with Omicron, especially children and young boys, and the only affordable evidence is a rapid or swab test, it is highly important to have other options to determine an infection with the Omicron variant, even if the patient does not feel anything at all [1,2]. Two types of skin rashes may be the distinguishing symptoms for individuals who have contracted Omicron and canno
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16

Sobolenkova, V. S., S. Yu Fedorov, and N. S. Rudneva. "Rare Forms of Exanthems in Pediatric Clinical Practice." CHILDREN INFECTIONS 17, no. 4 (2018): 65–68. http://dx.doi.org/10.22627/2072-8107-2018-17-4-65-68.

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The infant roseola, viral pemphigus, papular-hemorrhagic rash as a form of gloves and socks syndrome, and one-sided laterothoracic exanthema can be referred to the rare types of infectious rash in the pediatrician’s practice. These diseases, despite certain signs peculiar to everyone, are often not diagnosed during the initial admission to a pediatrician. The study describes the characteristics of each type of rash, the course of the disease, and discusses possible errors in the primary diagnosis of rare infectious rashes.
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17

Pan, Chien-Hsiung, Nitya Nair, Robert J. Adams, et al. "Dose-Dependent Protection against or Exacerbation of Disease by a Polylactide Glycolide Microparticle-Adsorbed, Alphavirus-Based Measles Virus DNA Vaccine in Rhesus Macaques." Clinical and Vaccine Immunology 15, no. 4 (2008): 697–706. http://dx.doi.org/10.1128/cvi.00045-08.

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ABSTRACT Measles remains an important cause of vaccine-preventable child mortality. Development of a low-cost, heat-stable vaccine for infants under the age of 6 months could improve measles control by facilitating delivery at the time of other vaccines and by closing a window of susceptibility prior to immunization at 9 months of age. DNA vaccines hold promise for development, but achieving protective levels of antibody has been difficult and there is an incomplete understanding of protective immunity. In the current study, we evaluated the use of a layered alphavirus DNA/RNA vector encoding
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18

Ortega-Parra, Camilo A., Elie Donath, Salvador Ricardo Garcia, and Robert J. Jacobson. "Correlation between development of rash and efficacy of EGFR inhibitors: A meta-regression analysis." Journal of Clinical Oncology 31, no. 15_suppl (2013): e13539-e13539. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e13539.

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e13539 Background: Treatment with Epidermal Growth Factor (EGFR) inhibitors is frequently characterized by the presence of a rash. Previous research has suggested that developing this rash may be associated with improved outcomes. It has been difficult, however, to establish a direct link between occurrence of a rash and tumor response. Rashes are also likely to occur with greater drug exposure and it is possible that they exist as a confounder in the well established relationship between drug exposure/dosing and tumor response. The purpose of this meta-regression analysis is to define whether
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Salugina, S. O., E. S. Fedorov, N. S. Lev, et al. "SAVI SYNDROME: LITERATURE REVIEW AND FAMILY CASE IN RHEUMATOLOGY AND PULMONOLOGY." Pediatria. Journal named after G.N. Speransky 100, no. 5 (2021): 180–87. http://dx.doi.org/10.24110/0031-403x-2021-100-5-180-187.

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SAVI syndrome – STING-associated early-onset vasculopathy – a rare monogenic autosomal dominant autoinflammatory disease associated with a mutation in the TMEM173 gene, belongs to type 1 interferonopathies. It is characterized by early onset, fever, skin rashes (vasculopathy), arthritis, interstitial lung disease (ILD), increased levels of acute phase markers, and the presence of autoantibodies (antinuclear factor, rheumatoid factor and other antibodies). The main treatment is glucocorticoids, JAK inhibitors. This publication provides an overview of the literature on this rare disease, as well
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Singalavanija, Srisupalak, and Ilona J. Frieden. "Diaper Dermatitis." Pediatrics In Review 16, no. 4 (1995): 142–47. http://dx.doi.org/10.1542/pir.16.4.142.

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Epidemiology Diaper rashes are among the most common skin disorders of infancy. In one survey of 1089 infants, diaper dermatitis occurred in 50%; however, only 5% had severe rash. The peak incidence of diaper dermatitis is between 9 and 12 months of age. The relation between age and the frequency of diaper dermatitis may result from several factors, including dietary changes from breast milk to formula milk and solid foods during the first 12 months of life. Breastfed infants have fewer diaper rashes than do formula-fed infants. The incidence of diaper dermatitis is 3 to 4 times higher in infa
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Singh, Avinash Kumar, Gaurav Dixit, Sanjeev Sharma, et al. "Skin Manifestations associated with Mantle cell Lymphoma: a case report." Mediterranean Journal of Hematology and Infectious Diseases 5, no. 1 (2013): e2013020. http://dx.doi.org/10.4084/mjhid.2013.020.

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Mantle cell lymphoma (MCL) is a distinct type of non-Hodgkin’s lymphoma that commonly affects extra nodal sites. The most commonly affected sites are bone marrow, gastrointestinal tract and Waldeyer’s ring, however, skin is rarely involved. We report a case of 56 year-old gentleman with MCL; exhibiting multiple large maculopapular skin rashes and skin ulcers. Histopathological examination had not shown direct infiltration by any atypical cells. He had significant improvement of skin lesions with combination chemotherapy and debridement. Awareness of skin manifestations of MCL is essential for
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Yadav, Dipa, Avinash Yadav, Sushmita Bhandari, and Umesh Kumar Singh. "Systemic Lupus Erythematosus Associated with Mixed-Type Autoimmune Hemolytic Anaemia and Vitamin B 12 Deficiency - A Case Report." Journal of Nepal Paediatric Society 44, no. 2 (2024): 62–64. https://doi.org/10.60086/jnps1236.

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Systemic lupus erythematosus (SLE) is a chronic complex autoimmune disease. It generally presents with a wide spectrum of hematological and immunological abnormalities involving multiple systems. Autoimmune hemolytic anemia (AIHA) is a rare, acquired condition where the lifespan of red blood cells is shortened and very rarely associated with SLE. We report a 13 years old girl who presented to our emergency department with complaints of intermittent fever, generalized weakness, dizziness and rashes over the trunk and abdomen for three days. On examination, she was clinically stable and investig
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Ambarchyan, Eduard T., Vladislav V. Ivanchikov, Anna L. Arakelyan та ін. "TNF-α Inhibitor-Induced Psoriasis and Psoriatic Alopecia in Adolescent with Ulcerative Colitis: Clinical Case". Current Pediatrics 22, № 5 (2023): 470–76. http://dx.doi.org/10.15690/vsp.v22i5.2635.

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Background. Genetically engineered biological therapy has revolutionized the treatment of many chronic inflammatory diseases. It often allows to achieve significant clinical effect and improve the patient's quality of life. However, sometimes it leads to adverse events, and physicians encounter them more often. One of such side effects is paradoxical psoriasis (PP) that can be revealed during the therapy with tumor necrosis factor alpha (TNF-α) inhibitors. PP is the debut or exacerbation of pre-existing psoriasis.Clinical case description. Patient A., 17 years old, has suffered from ulcerative
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Jurkėnaitė, Milena, and Zita Gierasimovič. "The Use of Glycolic Acid for Aesthetic Skin Renewal." Slauga. Mokslas ir praktika 3, no. 6 (306) (2022): 22–28. http://dx.doi.org/10.47458/slauga.2022.3.16.

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Acids such as chemical peels effectively improve the condition of the skin, inhibit inflammatory processes.&#x0D; The aim – to determine the effect of cosmetic products with glycolic acid on facial skin.&#x0D; Method. An unstructured interview was conducted during qualitative research. Two study participants were selected in the target selection: 1st participant (29 years old), 2nd participant (22 years old). The client card was filled in, a course of glycolic acid procedures was performed individually, with a frequency of every 10 days. Photos were taken before and after each procedure to eva
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Jumanova, А. E., C. A. Ospanova, and Z. M. Sukhanberdiyeva. "CLINICAL CASE: GOTTRON'S PROGRESSIVE ERYTHROKERATODERMA." Questions of dermatology and venereology, no. 4(90) (December 29, 2024): 00016077–20. https://doi.org/10.61075/kncdiz-2707-3696.2024.90.4.003.

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The article describes a case of Gottron's erythrokeratoderma, which is characterized by a predominantly autosomal dominant type of inheritance and refers to keratinization disorders with increased epidermal cell proliferation. A rare clinical case of autosomal recessive progressive symmetrical Gottron's erythrokeratoderma is described, characterized by seasonal changes in the skin pathological process - the appearance of rashes in winter and complete remissions in summer. Мақалада негізінен аутосомды-доминантты тұқым қуалаушылық түрімен сипатталатын және эпидермис жасушаларының пролиферациясын
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Shivamallappa, Madhusudhan Demahalli, Anna Mullins, and Kathryn Browning Carmo. "Bullous eruptions in transient abnormal myelopoiesis with normal phenotype." BMJ Case Reports 16, no. 4 (2023): e251523. http://dx.doi.org/10.1136/bcr-2022-251523.

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Cutaneous lesions are common manifestation of congenital leukaemia especially myeloid type with incidence of 25%–50% in reported cases. It is relatively rare in transient abnormal myelopoiesis (TAM) seen in trisomy 21 (~10%). The rashes seen in leukaemia and TAM are different. We report a case with a rare presentation of confluent bullous eruption in a phenotypically normal neonate with trisomy 21 restricted to haematopoietic blast cells. This rash resolved rapidly after low-dose cytarabine therapy with normalisation of total white cell counts. The risk of Down syndrome-associated myeloid leuk
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Bramantono, Bramantono, Henry Sutanto, Hermawan Susanto, Muhammad Vitanata Arfijanto, and Usman Hadi. "Diagnostic and Therapeutic Approaches for a Diabetic Patient Presenting with Secondary Syphilis and Severe Odynophagia." Medicina 60, no. 2 (2024): 298. http://dx.doi.org/10.3390/medicina60020298.

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Syphilis, an infectious disease caused by the spirochete Treponema pallidum, represents a pervasive global epidemic. Secondary syphilis is typically marked by the emergence of highly contagious mucocutaneous manifestations, including non-pruritic rashes on the palms and soles of the feet, alopecia, mucous patches, and condyloma lata. Here, we report a rare case of a 30-year-old male with newly discovered type 2 diabetes mellitus who presented with severe odynophagia due to secondary syphilis, confirmed by both nontreponemal VDRL/RPR and treponemal TPHA tests. Following the administration of a
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Abdullahi, Sakina M., Hafsat W. Idris, Halima A. Sadiku, and El-ishaq Abubakar. "GM1-gangliosidosis in a Nigerian infant: A case report." Nigerian Journal of Paediatrics 48, no. 1 (2021): 50–53. http://dx.doi.org/10.4314/njp.v48i1.10.

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Gangliosidoses belong to the group of genetic lipid metabolism disorders, caused by defects of lysosome enzymes, inherited as an autosomal recessive trait. Gangliosidosis GM1 is caused by the deficiency of the acid beta-galactosidase (GLB11) resulting in the storage of the substrate- GM1 ganglioside in brain and visceral organs. GM1 gangliosidosis comprises three phenotypes, depending on the age of onset: an infantile, juvenile and adult type. In the infantile type dysmorphic features, severe psychomotor retardation, hepatosplenomegaly, bone changes and a cherry red spot in the macular region
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Saqib, Aaisha, Yik Man, Rayan Ismail, and Dulmini Kariyawasam. "Rare case of type B insulin resistance in association with systemic lupus erythematosus: illustrating diagnostic and management challenges." BMJ Case Reports 14, no. 8 (2021): e242960. http://dx.doi.org/10.1136/bcr-2021-242960.

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A 42 year-old Caribbean woman with, known type 2 diabetes, was admitted with worsening fatigue, arthritis and rashes. She was diagnosed with multisystem systemic lupus erythematosus and was initially treated with systemic steroids. During this admission, she had persistently elevated capillary glucose levels with insulin requirements over 8 U/kg/day that still did not control her blood glucose levels. Due to her profound hyperglycaemia, serum samples of fasting insulin, C-peptide, paired with blood glucose were analysed, which confirmed significant hyperinsulinaemia. Further analysis confirmed
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Prokopiv, O. V., S. A. Lysheniuk, H. M. Karmazin, and V. V. Bilavka. "A case of septicemia with meningitis caused by Neisseria weaveri in a 7-year-old child." CHILD`S HEALTH 19, no. 1 (2024): 25–29. http://dx.doi.org/10.22141/2224-0551.19.1.2024.1667.

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A rare case of severe septicemia with meningitis that developed as a result of infection with non-pathogenic Neisseria weaveri, which is better known as the commensal of the dogs’ oral cavity, is described in a child aged 7 years. The disease began acutely with fever up to 39 °C and vomiting. Later, these symptoms were accompanied by delusions, psychomotor agitation, sharp pallor of the skin and convulsions. Subsequently, the skin became cyanotic, hemorrhagic rashes appeared throughout the body. With the abovementioned symptoms, the patient was admitted to the intensive care unit of infectious
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Nihira, H., K. Nakagawa, K. Izawa, et al. "Fever of unknown origin with rashes in early infancy is indicative of adenosine deaminase type 2 deficiency." Scandinavian Journal of Rheumatology 47, no. 2 (2017): 170–72. http://dx.doi.org/10.1080/03009742.2017.1324912.

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32

Prasad, Tulsi. "Measles like syndrome after measles and rubella vaccination." International Journal of Contemporary Pediatrics 8, no. 7 (2021): 1275. http://dx.doi.org/10.18203/2349-3291.ijcp20212485.

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National vaccination program (NIS, IAP) provides vaccination for measles and rubella (MR vaccine) for all children below 15 years of age. After vaccination with live attenuated viruses, the virus replicates on a limited scale. Replication may lead to mild symptoms occurring 5-14 days after MR-vaccination including fever, conjunctivitis and rash but sometimes it leads to florid type of severe rashes which are indistinguishable from a wildtype measles infection. A measles like syndrome may occur following MR vaccination, although it seems to be a rare event and therefore as a pediatrician we mus
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Sukakul, Thanisorn, and Supenya Varothai. "Chronic Paronychia and Onychomadesis in Pemphigus Vegetans: An Unusual Presentation in a Rare Autoimmune Disease." Case Reports in Medicine 2018 (2018): 1–4. http://dx.doi.org/10.1155/2018/5980937.

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Pemphigus vegetans is a rare variant of deep acantholytic pemphigus which usually presents with vesiculobullous rash and vegetative plaques on the folds. We report a case of pemphigus vegetans patient who presented with rashes on tips of fingers and toes resembling paronychia and onychomadesis that misled the diagnosis for months. The final diagnosis of Hallopeau-type pemphigus vegetans was made based on histopathology and direct immunofluorescence studies. Interestingly, not only the clinical presentation was atypical, but blood tests for anti-desmoglein 1 and 3 antibodies by ELISA technique
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Das, Koushik. "Formulation and Evaluation of Herbal Facewash Preventing Dermatological Problem." International Journal for Research in Applied Science and Engineering Technology 11, no. 6 (2023): 2216–25. http://dx.doi.org/10.22214/ijraset.2023.54016.

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Abstract: Facewash is one type of cosmeceuticals as well as semisolid dosage forms used for external purposes. It is applied on the skin surface to protect the skin from various microbial attacks. This type of cosmeceutical is also used to clean different types of skin problems like skin acne, skin pimples, skin rashes, dark circles, black spot, oily skin, skin discolored, etc. In this study, we have formulated one herbal face wash containing different extraction of herbal materials like fresh aloevera gel, leaves of neem, turmeric, lemon juice, Fresh leaves of Tulsi, fresh pudina leaves, Chan
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Martin, Gary R., Kimiora Henare, Carolina Salazar, et al. "Expression of a constitutively active humanSTINGmutant in hematopoietic cells produces anIfnar1-dependent vasculopathy in mice." Life Science Alliance 2, no. 3 (2019): e201800215. http://dx.doi.org/10.26508/lsa.201800215.

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STING-associated vasculopathy with onset in infancy (SAVI) is an autoinflammatory disorder characterized by blood vessel occlusions, acral necrosis, myositis, rashes, and pulmonary inflammation that are the result of activating mutations in the STimulator of Interferon Genes (STING). We generated a transgenic line that recapitulates many of the phenotypic aspects of SAVI by targeting the expression of the human STING-N154S–mutant protein to the murine hematopoietic compartment.hSTING-N154Smice demonstrated failure to gain weight, lymphopenia, progressive paw swelling accompanied by inflammator
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Kurtas, Nehir, Filippo Arrigoni, Edoardo Errichiello, et al. "Chromothripsis and ring chromosome 22: a paradigm of genomic complexity in the Phelan-McDermid syndrome (22q13 deletion syndrome)." Journal of Medical Genetics 55, no. 4 (2018): 269–77. http://dx.doi.org/10.1136/jmedgenet-2017-105125.

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IntroductionPhelan-McDermid syndrome (PMS) is caused by SHANK3 haploinsufficiency. Its wide phenotypic variation is attributed partly to the type and size of 22q13 genomic lesion (deletion, unbalanced translocation, ring chromosome), partly to additional undefined factors. We investigated a child with severe global neurodevelopmental delay (NDD) compatible with her distal 22q13 deletion, complicated by bilateral perisylvian polymicrogyria (BPP) and urticarial rashes, unreported in PMS.MethodsFollowing the cytogenetic and array-comparative genomic hybridization (CGH) detection of a r(22) with S
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Mulyani, Mulyani, Fijri Rachmawati, Astriana Astriana, and Nurul Isnain. "Giving Olive Oil Affects The Healing Of Napper Rashes In Babies." Jurnal Kebidanan Malahayati 9, no. 2 (2023): 226–33. http://dx.doi.org/10.33024/jkm.v9i2.7757.

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Latar Belakang Menurut IDAI (Ikatan Dokter Anak Indonesia) angka kejadian ruam popok di Indonesia pada tahun 2017 mencapai 7-35%, dengan angka terbanyak pada usia 9-12 bulan dan pada bayi laki-laki dan perempuan berusia dibawah tiga tahun. Selain itu, dari beberapa penelitian menunjukan bahwa hasil penelitian yang dilakukan di Lampung terdapat bayi yang mengalami ruam popok sebanyak 21,14%.Tujuan Diketahui pengaruh pemberian minyak zaitun terhadap penyembuhan ruam popok pada bayi di Wilayah Kerja Puskesmas Tulang Bawang Baru Kecemasan Bunga Mayang Tahun 2022.Metode Jenis penelitian menggunakan
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Eudy, Amanda M., Jennifer L. Rogers, Amy Corneli, et al. "Intermittent and Persistent Type 2 lupus: patient perspectives on two distinct patterns of Type 2 SLE symptoms." Lupus Science & Medicine 9, no. 1 (2022): e000705. http://dx.doi.org/10.1136/lupus-2022-000705.

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ObjectiveWe have developed a new conceptual model to characterise the signs and symptoms of SLE: the Type 1 and 2 SLE Model. Within the original model, Type 1 SLE consists of inflammatory manifestations like arthritis, nephritis and rashes; Type 2 SLE includes symptoms of fatigue, myalgia, mood disturbance and cognitive dysfunction. Through in-depth interviews, we explored how the Type 1 and 2 SLE Model fits within the lived experience of patients with SLE, with a focus on the connection between Type 1 and Type 2 SLE symptoms.MethodsSemistructured in-depth interviews were conducted among adult
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Kruglova, L. S., N. V. Gryazeva, and P. A. Uspenskaya. "Topical therapy for psoriasis: algorithms for the use of activated zinc pyrithione." Medical alphabet, no. 25 (December 6, 2024): 59–64. https://doi.org/10.33667/2078-5631-2024-25-59-64.

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Treatment of any type of psoriasis involves the use of external therapy. Recommended topical preparations include: corticosteroids, calcipotriol in combination with corticosteroids, zinc pyrithione, keratolytics, tar. A special place in the therapy of psoriasis is occupied by a drug containing activated zinc pyrithione (Skin-cap), due to its effectiveness, safety and the availability of various forms (aerosol, cream, shampoo), which allows it to be used in both short-term and long-term therapy at different stages of the disease. Complex treatment, including the use of topical forms containing
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Osei Sekyere, John. "Antibiotic Types and Handling Practices in Disease Management among Pig Farms in Ashanti Region, Ghana." Journal of Veterinary Medicine 2014 (September 11, 2014): 1–8. http://dx.doi.org/10.1155/2014/531952.

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Antibiotic resistance in bacteria is affected by the type of antibiotics used and how they are handled. The types of antibiotics used by 110 pig farms in the Ashanti region and the handling practices of the farmers during disease management were assessed. Injectable tetracycline, sulphadimidine, benzylpenicillin, and dihydrostreptomycin containing antibiotics were overly used by the farmers especially in the management of diarrhea, rashes, and coughs. Unsafe storage and disposal practices observed among the farms reflected the abysmal knowledge on appropriate use of antibiotics. Misdiagnosis a
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Ezeude, Chidiebele M., Arinze A. Onwuegbuna, Afoma M. Ezeude, et al. "Awareness of Chronic Complications of Diabetes Mellitus among Patients at St Charles Boromeo Specialist Hospital, Onitsha in South Eastern Nigeria." EAS Journal of Anaesthesiology and Critical Care 6, no. 06 (2024): 130–39. https://doi.org/10.36349/easjacc.2024.v06i06.004.

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Introduction: Diabetes mellitus (DM) is a chronic multisystemic disorders that causes complications that include long-term damage, dysfunction and failure of various organs in the body. Objective: The study aimed at determining the awareness of the chronic complication of DM that included ocular disorders, stroke, heart attack/heart failure, foot ulcer, skin rashes, sexual organs dysfunction and pregnancy losses by the subjects with DM at Onitsha, South Eastern Nigeria. Materials and Methods: This was a cross-sectional, descriptive hospital-based study involving 128 consenting DM subjects at S
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Kasikhina, E. I., N. N. Potekaev, О. R. Katunina, et al. "Dermatoscopic features of monomorphic lesions in cutaneous and indolent systemic mastocytosis." Meditsinskiy sovet = Medical Council, no. 23 (January 24, 2025): 206–14. https://doi.org/10.21518/ms2024-493.

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Introduction. Systematization of dermatoscopic signs of monomorphic rashes in mastocytosis has important practical significance.Aim. To carry out an analysis of dermatoscopic patterns of monomorphic eruption in monomorphic maculopapular cutaneous mastocytosis (mMPCM) and indolent systemic mastocytosis (ISM) and compare the results obtained with pathomorphological signs of mastocytosis.Materials and methods. The study included 6 children aged 4 to 14 years, 27 adolescents and adult aged 15 to 40 years with a monomorphic type of maculopapular cutaneous mastocytosis (MPCM) and 3 patients (minimum
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Efanova, Elena N., and Daria G. Taskaeva. "Combination of Psoriasis and Vitiligo in a Child with Sotos Syndrome: Clinical Case." Current Pediatrics 23, no. 2 (2024): 111–15. http://dx.doi.org/10.15690/vsp.v23i2.2742.

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Background. Psoriasis and vitiligo are chronic, relatively common dermatological diseases. Meanwhile, their combination in children is rare. The combination of psoriasis and vitiligo in a child with Sotos syndrome has not been previously described. Clinical case description. The boy, 10 years old, was hospitalized with complaints (according to his mother) of rashes on the scalp, body, and limbs, with mild itching that was not related to the time of day. The pathological skin process was widespread. The patient was hyperactive, restless, emotionally labile, irritable. Complaints of rashes was m
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Shachnev, A. S., O. V. Zhukova, and E. I. Kasikhina. "Clinical and anamnestic features of dyshidrotic eczema: A cross-sectional study." Meditsinskiy sovet = Medical Council, no. 2 (March 31, 2025): 73–80. https://doi.org/10.21518/ms2025-054.

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Introduction. Dyshidrotic eczema (DE) is a common type of eczema characterized by vesicular or bullous rashes on the skin of hands and (or) feet, prone to chronic and recurrent course, refractoriness to therapy and development of complications.Aim. To analyze the clinical and anamnestic features of dyshidrotic eczema. Describe clinical cases of DE and experience with external therapy.Materials and methods. The study included 132 patients (55 men and 77 women) with DE aged 19 to 78 years, the average age was 33.7 ± 10.3 years. To assess the severity of the course of DE, The Dyshidrotic Eczema A
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Onbaşı Karabağ, Şenay, Ruveydanur Keçici, Betül Aksoy, et al. "Coexistence of Celiac Crisis and Food Allergy." Pediatric Academic Case Reports 3, no. 2 (2024): 19–23. https://doi.org/10.61107/pacr.2024.052.

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Celiac disease (CD) may present with different clinical manifestations, and very rarely, it may present with Celiac crisis, which is a fatal complication. An 18-month-old girl was referred to our center due to recurrent diarrheal attacks, inability to gain weight, malaise, fever, and poor general condition. It was learned that the patient, who was followed up in the intensive care unit during his last hospitalization, was examined for the etiology of chronic diarrhea. Celiac disease was suspected, and she was administered a short-term gluten-free diet, but no response was received. The patient
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Mahwish Ahmed, Neelam Ayub, Kiren Shaheryar, Sumaira Abdullah, Mariam Tariq, and Kazim Abbas Virk. "Association Between Dengue Skin Rash and Disease Outcome in A Tertiary Care Hospital." Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University 21, no. 1 (2025): 264–69. https://doi.org/10.48036/apims.v21i1.1512.

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Objective: The objective of this research work is to build upon existing knowledge by exploring the relationship between dengue skin rashes and disease course in a tertiary healthcare center. Methods: This descriptive cross sectional study was conducted in Dermatology department at HBS General Hospital, Islamabad. from January 2024 to August 2024. Total 188 confirmed dengue fever patients was performed. Researchers documented demographic information together with clinical features as well as laboratory findings and disease outcomes of all these patients. Dermatologists evaluated the presence,
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Mathotaarachchi, Bihara Rasanjalee, Obuhovich Anneta Romualdovna, K. A. Nethuki Akithma Kulasinghe, Kuvindu Janeth Weerasekara, and Sandeepa Abhishek Hewage. "A Rare Case of Latent Syphilis Mimicking Dermal Angiitis of Ulcerative Necrotic Type: A Case Report." International Journal of Science and Healthcare Research 10, no. 2 (2025): 103–10. https://doi.org/10.52403/ijshr.20250212.

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Diagnosing syphilis, a bacterial sexually transmitted infection, is often challenging due to its multitude of clinical symptoms. Even though the variety of clinical symptoms of syphilis is well understood, unusual presentations can develop. Due to diagnostic challenges and treatment delays brought on by the disease's ability to mimic other skin conditions, deviate from typical clinical presentations, and take on unusual forms, atypical presentations represent a serious risk of spreading. This case report presents an unusual manifestation of latent syphilis mimicking dermal angiitis of ulcerati
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Kumar, Sudhir, Kirti Nirmal, Amit Kumar Nirmal, and S. K. Bhattacharya. "Cefixime and Ofloxacin fixed dose combination induced petechial rash: a case report." International Journal of Basic & Clinical Pharmacology 6, no. 1 (2016): 211. http://dx.doi.org/10.18203/2319-2003.ijbcp20164782.

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Petechial rash is a type of rash which is associated with many infectious and non-infectious conditions. We present a case of Petechial rash induced by administration of cefixime with ofloxacin tablet. A eighteen year old male patient reported to us with a presentation of rash with itching for three days on administration of the fixed dose combination of cefixime + ofloxacin along with paracetamol for the previous symptoms of fever with chills, headache and bodyache. Patient describes itching in the rash which is increasing. The duty doctor attended the patient and immediately stopped the furt
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Moreno Lozano, Lucía, Mera De Aramburu, and Carmen Bermúdez-Hormigo. "Chronic disease underlying hives: beyond the itch." Revista Alergia México 71, no. 1 (2024): 44–46. http://dx.doi.org/10.29262/ram.v71i1.1245.

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Introduction: Short-lasting erythematous-papular skin rashes suggest a clinical diagnosis of urticaria. However, it may be another type of dermatitis whose diagnosis may require complementary examinations. Case report: 53-year-old woman diagnosed in 2016 with diffuse large B-cell lymphoma in complete remission. Since 2010 she presented daily episodes of erythematous-papular lesions lasting 24-36 hours. She was treated with antihistamines, oral corticosteroids and Omalizumab without control. A study was carried out consisting of: Blood tests: haemogram, serum immunoglobulins, thyroid hormones,
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Stannard, JN, TJ Reed, JM Kahlenberg, EM Myers, L. Lowe, and JE Gudjonsson. "ID: 132: LUPUS KERATINOCYTES ARE PRIMED BY AN AUTOCRINE TYPE I INTERFERON LOOP TO ROBUSTLY SECRETE IL-6." Journal of Investigative Medicine 64, no. 4 (2016): 976.2–977. http://dx.doi.org/10.1136/jim-2016-000120.136.

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BackgroundCutaneous lupus erythematosus (CLE) is a disfiguring disease that can affect up to 70% of patients with systemic lupus. Treatment modalities are often ineffective and flares are frequent. Interleukin-6 (IL-6) is a pro-inflammatory cytokine which has gotten recent attention in SLE as IL-6 is increased in the serum of active patients and blockade of IL-6 is therapeutic in murine lupus models and phase I human trials. The source of IL-6 in CLE remains unclear.MethodsAll studies were approved by the University of Michigan Internal Review Board (IRB# 72843 and 66116 to JMK). RNA was isola
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