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Dissertations / Theses on the topic 'Macrocyclic chemistry'

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1

Tuffin, Rachel Patricia. "Macrocyclic liquid crystals." Thesis, University of Hull, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337245.

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2

Nicholson, Patrick Edmund. "Synthetic macrocyclic ionophores." Thesis, Durham University, 1989. http://etheses.dur.ac.uk/6321/.

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14-Crown-4 derivatives bearing either one or two oxymethyl, benzyl- oxymethyl, methoxycarbonylmethyl or carbamoylmethyl substituents have been prepared in an attempt to obtain selective ionophores for lithiumions. Complexation has been monitored by IR, (^13)C NMR, Fast Atom Bombardment Mass Spectrometry, and solvent polymeric membranes have been fabricated and evaluated using the fixed interference method. Improved lithium selectivities of the disubstituted 14-crown-4 ligands compared to the monosubstituted analogues in the potentiometric experiments, bears out the premise that there is a need
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3

Kyte, A. B. "Chiral macrocyclic receptors." Thesis, University of Liverpool, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354552.

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4

Martí-Centelles, Vicente, M. Isabel Burguete, and Santiago V. Luis. "Chemistry inspired by nature: macrocyclic pseudopeptides design." Revista de Química, 2013. http://repositorio.pucp.edu.pe/index/handle/123456789/100172.

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El diseño molecular fundamentado en la imitación de las complejas estructuras y procesos que se encuentran en la naturaleza se conoce como Química bioinspirada o Química biomimética. Una de las aproximaciones utilizadas en esta disciplina es la preparación de compuestos seudopeptídicos macrocíclicos a partir de aminoácidos naturales y componentes abióticos. En la naturaleza existen proteínas con propiedades muy específicas y diversas. El uso de la información codificada en las cadenas laterales de los aminoácidos es un factor clave que, a su vez, puede utilizarse con ventaja para el diseño de
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5

Göransson, Ulf. "Macrocyclic polypeptides from plants." Doctoral thesis, Uppsala University, Department of Medicinal Chemistry, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1956.

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<p>The aim of this work was to explore the structural and functional diversity of polypeptides that are found in plants. Expanding knowledge of simililarities between plant use of these compound and animal use promises exceptional opportunities for finding, from plant research, new structures with biomedical and biotechnological potential.</p><p>A fractionation protocol was developed and applied to many plant species, providing fractions enriched in polypeptides, amenable to chemical and biological evaluation. From one species, the common field pansy (<i>Viola arvensis</i>), a 29-amino-acid re
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6

Richtzenhain, Heiko. "Macrocyclic liquid crystals." Thesis, University of Nottingham, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243475.

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7

Salek, Spencer N. "Macrocyclic tridentate phosphathia ligands." Thesis, University of Kent, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242928.

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8

Lippolis, Vito. "Studies on the coordination chemistry of macrocyclic ligands." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311755.

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9

Rawle, Simon Charles. "The coordination chemistry of some multidentate thioether ligands." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329963.

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10

Tei, Lorenzo. "Studies on functionalised macrocyclic ligands." Thesis, University of Nottingham, 2001. http://eprints.nottingham.ac.uk/12386/.

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The work presented in this thesis hinges on three main topics: a) the coordination chemistry of symmetric and asymmetric derivatives of [9]aneN3 towards lanthanide ions; b) the transition metal co-ordination chemistry of nitrile and amino derivatives of [9]aneN3 and [15]aneN3O2; c) the use of macrocyclic ligands for the synthesis of polymeric Ag' complexes. Chapter 3 describes the Ln"' complexes of the ligand obtained by Schiffbase condensation of 1,4,7-tris(2-aminoethyl)-1,4,7-triazacyclononane (L) with three molar equivalents of sodium pyruvate using the Ln0' ion as templating agent. The mon
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11

Gelling, Andrew. "Macrocyclic and chelation chemistry of thioalkyne dicobalt hexacarbonyl complexes." Thesis, University of Kent, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314487.

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12

Labat, Gaël Charles. "Structure and mechanism in macrocyclic systems." Thesis, Nottingham Trent University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251938.

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13

Qu, Wenchao. "SYNTHESIS OF FUNCTIONALIZED MACROCYCLIC POLYTHIAETHERS." University of Akron / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=akron1137687463.

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14

Smith, Richard John Alan. "The synthesis of macrocyclic receptor compounds." Thesis, University of Liverpool, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328435.

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15

Najera, Blanca A. "Schiff base macrocyclic ligands and their complexes." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301827.

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16

Yates, P. C. "Investigation of molecular structure of macrocyclic complexes." Thesis, University of Reading, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373770.

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17

Ellis, Sandra Ann. "Catalytic oxidations using polyoxometalates and macrocyclic compounds." Thesis, University of Liverpool, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250436.

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18

Hamilton, Caroline. "Investigations of macrocyclic esters and ether-esters." Thesis, University of York, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298341.

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19

Hyde, Timothy I. "Studies on transition metal tetraaza macrocyclic complexes." Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/28273.

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20

Quirk, Jeffrey. "Coordination chemistry of selenoether macrocyclic ligands with transition metal ions." Thesis, University of Southampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242624.

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21

Lorenzo, Susan Chemistry Faculty of Science UNSW. "The supramolecular chemistry of cucurbituril molecules." Awarded by:University of New South Wales. School of Chemistry, 2006. http://handle.unsw.edu.au/1959.4/26990.

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The set of molecules cucurbit[n]uril (Qn) are macrocycles composed of n glycoluril monomers linked by methylene groups. These molecules have two oxygen-ringed portals of a diameter slightly smaller than their internal cavity diameter. This thesis describes syntheses, crystallisations, crystal structure determinations, crystal packing analyses and force field calculations exploring the supramolecular chemistry of Qn molecules and their derivatives. Qn acts as a host for guest molecules and at the outset of this project no metal containing molecule had been encapsulated in a Qn molecule. One aim
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22

Sandanayake, Kaththota Ralalage Arunasiri S. "Fluorescent macrocyclic sensors for alkali and other cations." Thesis, Queen's University Belfast, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356861.

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23

Harriott, Patrick. "Pendant-arm macrocyclic ligands and their metal complexes." Thesis, Queen's University Belfast, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336108.

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24

Henley, Peter Dominic. "Studies towards synthetic macrocyclic receptors for small peptides." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284677.

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25

Chung, Lap-Yan. "Synthesis and study of macrocyclic and related compounds." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.330163.

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26

Kostiuk, Sarah Louise. "The total synthesis of macrocyclic bisbibenzyl natural products." Thesis, University of Southampton, 2009. https://eprints.soton.ac.uk/193731/.

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This thesis is concerned with the total synthesis of two related macrocyclic natural products, cavicularin and riccardin C. Cavicularin is particularly noteworthy owing to its interesting structure: its 14-membered macrocyclic core imparts sufficient strain on the system to force one of the arenes in this paracycophane to adopt a boat-shaped conformation, deviating from planarity. The natural product also exhibits optical activity despite containing no chiral centres, this being due to axial and planar chirality in the molecule. Herein, routes to these two natural products are presented. Key s
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27

Smith, David John. "Complexation of amino-acid derivatives using macrocyclic receptors." Thesis, University of Bath, 1996. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319219.

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28

Hébert, Normand C. 1930. "Methods for the synthesis of macrocyclic and bolaform phosphatidylcholines." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=70273.

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A general strategy for the synthesis of phospholipids was developed. The method was demonstrated using 3-O-allyl-sn-glycerol 33 which was regiospecifically converted to 1-palmitoyl-2-(5-O-TBDMS-stearoyl)-3-O-allyl-sn-glycerol 43 by the sequential acylation of the primary and secondary hydroxyls. The allyl group was removed in two steps by isomerization to a vinyl ether and hydrolysis with N-bromosuccinimide in aqueous tetrahydrofuran. A new method for the conversion of the 1,2-diacylglycerols to phosphatidylcholines under acid-catalyzed conditions was developed. The diacylglycerols were treate
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29

Limon, Matthieu. "Synthesis and coordination chemistry of functionalised and macrocyclic phosphines and arsines." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/54767/.

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The results presented in this thesis are separated into three distinct sections. Chapter 2 describes the reaction of the manganese precursors Mn(OTf)(CO)3{o-C6H4(PH2)2}L 2.6, and Mn(OTf)(CO)3{C2H4(PH2)2} / 2.7, with a silver carbene transfer agent 1,3-dialtylbenzimidazol-2-ylidiene, 2.10, to give the new phosphido-phosphine manganese species 2.11 and 2.12. The resultant species 2.11 and 2.12 exist in two geometric forms, cis and trans, which have been characterised by X-Ray crystallography for 2.11. A new chiral rigid phospholane ligand 3(/)-hydroxy-phenylphospholane, 3.7, has been prepared fr
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30

Bushell, Karen Lynne. "The coordination chemistry of polypyridyl ligands with secondary macrocyclic binding sites." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301986.

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31

Hesford, Matthew James. "Synthesis and coordination chemistry of acyclic and macrocyclic tellurium-containing ligands." Thesis, University of Southampton, 2003. https://eprints.soton.ac.uk/361577/.

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32

Al, Jammaz Ibrahim J. "Solution chemistry of calix[4]arene amide derivatives : applications in radiopharmaceuticals." Thesis, University of Surrey, 1998. http://epubs.surrey.ac.uk/842865/.

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Following an overview in the field of calixarene chemistry given in the introduction, this thesis reports, i) The synthesis of p-text-butylcalix[4]arene tetraacetamides, thiophosphates and derivatives containing mixed functional groups and the characterisation by IR, NMR and microanalysis. ii) The solution thermodynamic of p-tert-butylcalix[4]arene tetradiisopropylacetamide and the transfer thermodynamics of this ligand from acetonitrile to various solvents. iii) Spectrophotometric, potentiometric and calorimetric studies on the interaction of p-tert-butylcalix[4]arene tetraacetamides and meta
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33

Klein, Jörg Martin. "Dynamic combinatorial chemistry of hydrazone and disulfide macrocycles." Thesis, University of Cambridge, 2011. https://www.repository.cam.ac.uk/handle/1810/252248.

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34

Savill, Karen. "Investigations of 1,2,4-trioxanes as precursors of macrocyclic lactones." Thesis, Heriot-Watt University, 1993. http://hdl.handle.net/10399/1392.

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35

McCroskey, Lucas C. "Synthesis of a Novel Macrocyclic Library and Small-Molecule Peptide Scaffolds." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1449158858.

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36

Parker, Laura Louise. "Macrocyclic nitrogen mustard prodrugs as hypoxia selective anti-cancer agents." Thesis, University of Glasgow, 2003. http://theses.gla.ac.uk/5364/.

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The low selectivity of chemotherapy is an ongoing problem in the treatment of cancer. Prodrugs that are activated in vivo provide a therapeutic advantage for selective cytotoxicity. Here we have designed redox-active compounds that are electrochemically reduced in hypoxic (poorly oxygenated) tissue, resulting in release of a nitrogen mustard cytotoxin. This thesis describes the synthesis of novel macrocyclic N-mustard drugs and the development of their Cu(II) complexes as hypoxia-selective prodrugs. (Fig. 3736A) The (2-trimethylsilyl)ethanesulfonyl (SES) protecting group is very versatile. It
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37

Haq, Ahsanul. "The preparation of macrocyclic compounds by thermolysis of cyclic peroxides." Thesis, Heriot-Watt University, 1992. http://hdl.handle.net/10399/1491.

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38

Barbour, R. H. "Synthesis and biological activity of macrocyclic diesters of synthanecine A." Thesis, University of Glasgow, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.480493.

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39

Cameron, J. F. "Approaches towards macrocyclic natural products using #pi#-allylnickel halide complexes." Thesis, University of Strathclyde, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382251.

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40

Comfort, Nigel Paul. "Conducting polymers with integral transition metal macrocyclic ligand sub-units." Thesis, University of Surrey, 1995. http://epubs.surrey.ac.uk/843830/.

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A number of novel tetraaza[14]annulene (TAA) ligands and their transition metal complexes have been synthesised, characterised and electrochemically investigated as monomer sub-units from which conducting polymer films can be prepared. Electrochemical analysis of the new ligand (p-NH2)2dptaaH2, prepared from the catalytic hydrogenation of (p-N02)2dptaaH2 at atmospheric pressure in DMF, shows three irreversible ligand-centred redox peaks in CH3CN electrolyte (L+0 = 0.48 V, L2+/+ = +1.02 V, L0/- = -1.44 V) with the oxidation peaks becoming reversible in CH2Cl2 electrolyte. Solutions of Ni(p-NH2)
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41

Marquez, Acuna Victoria Elena. "Coordination chemistry of macrocycles and metal complexes containing a nitrogen and sulphur donor set." Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279727.

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42

Batson, Joel Marcus. "The design and synthesis of linear and macrocyclic Poly(para-arylene)s." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/82311.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Poly(para-phenylene) (PPP) has generated sustained scientific interest due to its potential as a blue-emitting material for use in Organic Light Emitting Devices (OLEDs). However, due to its highly unfavorable solubility, most traditional synthetic routes to PPP are relatively limited in their scope. In Chapter 2 we discuss the synthesis of poly(para-arylene)s via the post polymerization functionalization of a completely soluble a
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43

Ballester, Maria. "Relative basicities of free base porphyrins : understanding the role of macrocyclic distortion." FIU Digital Commons, 2005. http://digitalcommons.fiu.edu/etd/1383.

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Porphyrins have been the center of numerous investigations in different areas of chemistry, geochemistry, and the life sciences. In nature the conformation of the porphyrin macrocycle varies, depending on the function of its apoenzyme. It is believed that the conformation of the porphyrin ring is necessary for the enzyme to achieve its function and modify its reactivity. It is important to understand how the conformation of the porphyrin ring will influence its properties. In synthetic porphyrins particular conformations and ring deformations can be achieved by peripheral substitution, metalla
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44

Hassen, J. H. "Spectroscopic analysis of adsorbed macrocyclic complexes on ceramic and related materials." Thesis, University of Essex, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.481601.

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45

Aris, Damian R. "Macrocyclic complexation of selected neutral and cationic p-block metal species." Thesis, University of Warwick, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369455.

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46

Pernia, Glen Javier. "Synthesis and binding properties of novel macrocyclic receptors for amino acids." Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296273.

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47

Kinney, Zacharias J. "Higher-Order Architectures Assembled from ortho-Phenylene Oligomers." Miami University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=miami1532351710225318.

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48

Uppal, Daljit Kaur. "Studies of the metal-binding sites in macrocyclic quadridentate ligands." Thesis, London Metropolitan University, 1986. http://repository.londonmet.ac.uk/3284/.

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49

Hamasharif, Muslih S. "Applications of azides in heterocyclic synthesis, macrocyclic synthesis and multicomponent reactions." Thesis, University of Huddersfield, 2016. http://eprints.hud.ac.uk/id/eprint/31079/.

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50

Chang, Shuh-Kuen. "Studies toward the total synthesis of amphidinol 3." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1150261354.

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