Academic literature on the topic 'Macrofluidic model'

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Journal articles on the topic "Macrofluidic model"

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Gome, Gilad, Benyamin Chak, Shadi Tawil, et al. "Cultivation of Bovine Mesenchymal Stem Cells on Plant-Based Scaffolds in a Macrofluidic Single-Use Bioreactor for Cultured Meat." Foods 13, no. 9 (2024): 1361. http://dx.doi.org/10.3390/foods13091361.

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Reducing production costs, known as scaling, is a significant obstacle in the advancement of cultivated meat. The cultivation process hinges on several key components, e.g., cells, media, scaffolds, and bioreactors. This study demonstrates an innovative approach, departing from traditional stainless steel or glass bioreactors, by integrating food-grade plant-based scaffolds and thermoplastic film bioreactors. While thermoplastic films are commonly used for constructing fluidic systems, conventional welding methods are cost-prohibitive and lack rapid prototyping capabilities, thus inflating res
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Çakal, Gaye Ö., İnci Eroğlu, and Saim Özkar. "Simulation of continuous boric acid slurry reactors in series by microfluid and macrofluid models." Journal of Crystal Growth 306, no. 1 (2007): 240–47. http://dx.doi.org/10.1016/j.jcrysgro.2007.04.058.

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Hilfiker, Rolf, and Hans-Friedrich Eicke. "Self-consistency of the percolation model as applied to a macrofluid-like water-in-oil microemulsion." Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases 83, no. 5 (1987): 1621. http://dx.doi.org/10.1039/f19878301621.

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Vass, Sz, T. Gilányi, and S. Borbély. "SANS Study of the Structure of Sodium Alkyl Sulfate Micellar Solutions in Terms of the One-Component Macrofluid Model." Journal of Physical Chemistry B 104, no. 9 (2000): 2073–81. http://dx.doi.org/10.1021/jp9934735.

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TIAN, FEI, WEIDONG SHI, and HUA JIANG. "INNER FLOW FIELD OF POOL MIXED BY THREE SUBMERSIBLE MIXERS." Journal of Advanced Manufacturing Systems 11, no. 02 (2012): 91–97. http://dx.doi.org/10.1142/s0219686712500072.

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To study the agitating effect of submersible mixers in a square sewage treatment pool, the three-dimensional modeling Pro/E software was adopted to establish the physical model. The large-scale computational fluid dynamics software FLUENT6.3 was used, and the large-scale software ICEM was selected to build an unstructured tetrahedron grid of the sewage treatment pool. Next, the sewage treatment pool was numerically simulated by RNG k-ε turbulent model and move coordinate system technology. The macrofluid field and the flow field distribution of each section were analyzed to observe the efficie
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Osawa, Takahiro, Wenchu Wang, Jinlu Dai, and Evan T. Keller. "Macrofluidic recirculating model of skeletal metastasis." Scientific Reports 9, no. 1 (2019). http://dx.doi.org/10.1038/s41598-019-50577-3.

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Abstract While microfluidic systems model aspects of metastasis, they are limited to artificially created tissues of limited complexity. We set out to develop an in vitro model of tumor cell migration from a primary tumor to a distant site that allows use of tissue. Accordingly, we created a macrofluidic model using culture plate wells connected with type I collagen-coated large bore tubing and has recirculating media. Green fluorescent protein-positive prostate carcinoma cells in a hydrogel or excised tumor xenografts from mice were placed into primary tumor sites and either human bone stroma
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Cui, Jingang, Wei Jiang, Jilei Su, Jiazhen Zhang, Yongliang Yu, and Yongsheng Ding. "Microfluidic-to-macrofluidic: A simple in vitro model of atherosclerosis induced by fluidic stimulation." Biomicrofluidics 17, no. 4 (2023). http://dx.doi.org/10.1063/5.0155267.

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Atherosclerosis is the narrowing of the arteries due to the formation of fatty plaques, which is the main cause of myocardial infarction and stroke. It is important to develop an in vitro model that can combine multiple-type cell co-culture, vessel wall-like structure, and fluid condition to simulate the processes of atherosclerosis. Herein, we used a simple microfluidic chip made of three polydimethylsiloxane layers to co-culture endothelial and smooth muscle cells in a flat rectangular microchannel. After being connected with a circulating culture medium driven by a peristaltic pump, the fla
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Kern, Axelle Y., Yevgeniy Kreinin, Lise Charle, Mark Epshtein, Netanel Korin, and Pierre H. Mangin. "A macrofluidic model to investigate the intrinsic thrombogenicity of clinically used stents and develop less thrombogenic stents." Heliyon, February 2024, e26550. http://dx.doi.org/10.1016/j.heliyon.2024.e26550.

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Cho, Youngkyu, Kyuhwan Na, Yesl Jun, Jihee Won, Ji Hun Yang, and Seok Chung. "Three-Dimensional In Vitro Lymphangiogenesis Model in Tumor Microenvironment." Frontiers in Bioengineering and Biotechnology 9 (October 4, 2021). http://dx.doi.org/10.3389/fbioe.2021.697657.

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Lymphangiogenesis is a stage of new lymphatic vessel formation in development and pathology, such as inflammation and tumor metastasis. Physiologically relevant models of lymphatic vessels have been in demand because studies on lymphatic vessels are required for understanding the mechanism of tumor metastasis. In this study, a new three-dimensional lymphangiogenesis model in a tumor microenvironment is proposed, using a newly designed macrofluidic platform. It is verified that controllable biochemical and biomechanical cues, which contribute to lymphangiogenesis, can be applied in this platfor
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Cherubini, Marta, Scott Erickson, Prasanna Padmanaban, et al. "Flow in fetoplacental-like microvessels in vitro enhances perfusion, barrier function, and matrix stability." Science Advances 9, no. 51 (2023). http://dx.doi.org/10.1126/sciadv.adj8540.

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Proper placental vascularization is vital for pregnancy outcomes, but assessing it with animal models and human explants has limitations. We introduce a 3D in vitro model of human placenta terminal villi including fetal mesenchyme and vascular endothelium. By coculturing HUVEC, placental fibroblasts, and pericytes in a macrofluidic chip with a flow reservoir, we generate fully perfusable fetal microvessels. Pressure-driven flow facilitates microvessel growth and remodeling, resulting in early formation of interconnected and lasting placental-like vascular networks. Computational fluid dynamics
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Dissertations / Theses on the topic "Macrofluidic model"

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Kern, Axelle Y. "La thrombose de stent : évaluation de l’importance de la rhéologie dans la thrombogénicité des stents et d’un nouvel agent pharmacologique dirigé contre la GPVI pour prévenir la thrombose de stent." Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAJ027.

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Une complication majeure de la pose d’un stent sur une plaque d’athérosclérose est la thrombose de stent, qui présente un taux de mortalité particulièrement élevé. La bithérapie antiplaquettaire, indiquée dans la prévention de cette complication, entraîne un risque important de saignement et n’est pas toujours efficace. L’objectif de ce travail de thèse a consisté à identifier les mécanismes de la thrombose de stent et à évaluer l’intérêt d’une nouvelle classe d'agents antiplaquettaires capables de la prévenir efficacement avec un risque hémorragique faible. Le développement d’un modèle macrof
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Yucel, Cakal Gaye O. "Dynamic Behavior Of Continuous Flow Stirred Slurry Reactors In Boric Acid Production." Phd thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12605047/index.pdf.

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One of the most important boron minerals, colemanite is reacted with sulfuric acid to produce boric acid. During this reaction, gypsum (calcium sulfate dihydrate) is formed as a byproduct. In this study, the boric acid production was handled both in a batch and four continuously stirred slurry reactors (4-CFSSR&rsquo<br>s) in series system. In this reaction system there are at least three phases, one liquid and two solid phases (colemanite and gypsum). In a batch reactor all the phases have the same operating time (residence time), whereas in a continuous reactor all the phases may have diff
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