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Journal articles on the topic 'Mactcp'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Anderson, Daniel K., and W. Michael Reed. "The Effects of Internet Instruction, Prior Computer Experience, and Learning Style on Teachers' Internet Attitudes and Knowledge." Journal of Educational Computing Research 19, no. 3 (1998): 227–46. http://dx.doi.org/10.2190/8wx1-5q3j-p3bw-jd61.

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What is now called the Internet started out as a small number of federally funded Department of Defense (Advanced Research Project Agency, or ARPA) supercomputers networked together to share information. In order to guarantee data transmission between these nodes, this network (ARPANET) shared a common set of protocols that was designed to allow for high speed and reliable transfer. This protocol suite is TCP/IP (Transmission Control Protocol/Internet Protocol). Most microcomputers now have a TCP/IP implementation available (e.g., MacTCP) and can, therefore, join the millions of computers that

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Pereira, Kleber F., Vanessa A. Menezes, and Eugênio G. de Araújo. "Anatomia comparativa da dura-máter de Sapajus libidinosus." Pesquisa Veterinária Brasileira 33, no. 10 (2013): 1263–68. http://dx.doi.org/10.1590/s0100-736x2013001000012.

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O Sapajus libidinosus é um primata do novo mundo popularmente conhecido como macaco-prego, geograficamente distribuído por todo território sul-americano, possui características de inquietude e habilidade de manipulação de ferramentas para a obtenção de alimentos. Este estudo teve por objetivo descrever a morfologia dos seios da dura-máter de Sapajus libidinosus numa perspectiva comparativa. Foram utilizados um total de 3 animais adultos e machos oriundos da Universidade Federal de Goiás e fixados em solução aquosa de formaldeído 10%. No encéfalo de S. libidinosus, foi possível observar a fissu

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ZIĘTKOWIAK, WOJMIR, DARIUSZ SZPUREK, MACIEJ WILCZAK, RAFAŁ MOSZYŃSKI, and STEFAN SAJDAK. "Didelphic uterus connected with incomplete transverse vaginal septum - case report." PRZEGLĄD GINEKOLOGICZNO-POŁOŻNICZY 4, no. 4-4 (2004): 197–201. http://dx.doi.org/10.1066/s10014040043.

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Pereira, Dayane Kelly Sabec, Eugênio Gonçalves de Araújo, Kleber Fernando Pereira, and Valcinir Aloisio Scalla Vulcani. "Anatomia encefálica comparativa de primatas humanos e não-humanos: uma revisão." Research, Society and Development 10, no. 2 (2021): e19810212441. http://dx.doi.org/10.33448/rsd-v10i2.12441.

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O estudo anatômico de primatas não-humanos, tem exercido função importante para intervenções clínicas e cirúrgicas em atendimento da medicina veterinária. Sabe-se que o modelo experimental mais conhecido na área científica é a Macaca mulatta, popularmente conhecido como macaco Rhesus e o que a literatura tem demonstrado são novos modelos experimentais que possam suprir estudos sobre o sistema nervoso central, sendo necessário para essas descobertas um aprofundamento maior na área da anatomia comparativa. O objetivo desta revisão de literatura é promover uma visão ampla sobre os aspectos anatôm

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Huang, SM, CJ Huang, WM Wang, JC Kang, and WC Hsu. "The enhancement of nuclear receptor transcriptional activation by a mouse actin-binding protein, alpha actinin 2." Journal of Molecular Endocrinology 32, no. 2 (2004): 481–96. http://dx.doi.org/10.1677/jme.0.0320481.

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The p160 coactivators, steroid receptor coactivator 1, glucocorticoid receptor interacting protein 1 (GRIP1) and the activator of thyroid and retinoic acid receptor, have two activation domains, AD1 and AD2, which transmit the activation signal from the DNA-bound nuclear receptor to the chromatin and/or transcription machinery. In screening for mammalian proteins that bind the AD2 of GRIP1, we identified a mouse actin-binding protein, alpha actinin 2 (mACTN2). mACTN2 was expressed in the heart, skeletal muscle, lung, brain and testis, but there was no expression in the spleen, liver or kidney.

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Zucker, Charles L., Paul S. Bernstein, Richard L. Schalek, Jeff W. Lichtman, and John E. Dowling. "A connectomics approach to understanding a retinal disease." Proceedings of the National Academy of Sciences 117, no. 31 (2020): 18780–87. http://dx.doi.org/10.1073/pnas.2011532117.

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Macular telangiectasia type 2 (MacTel), a late-onset macular degeneration, has been linked to a loss in the retina of Müller glial cells and the amino acid serine, synthesized by the Müller cells. The disease is confined mainly to a central retinal region called the MacTel zone. We have used electron microscopic connectomics techniques, optimized for disease analysis, to study the retina from a 48-y-old woman suffering from MacTel. The major observations made were specific changes in mitochondrial structure within and outside the MacTel zone that were present in all retinal cell types. We also

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BARTEN, DI-JANNE J. A., MARTIJN F. PISTERS, TIM TAKKEN, and CINDY VEENHOF. "Validity and Responsiveness of the Dutch McMaster Toronto Arthritis Patient Preference Questionnaire (MACTAR) in Patients with Osteoarthritis of the Hip or Knee." Journal of Rheumatology 39, no. 5 (2012): 1064–73. http://dx.doi.org/10.3899/jrheum.110876.

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Objective.To determine the content validity, the construct validity, and the responsiveness of the Dutch McMaster Toronto Arthritis Patient Preference Questionnaire (MACTAR) in patients with osteoarthritis (OA) of the hip or knee.Methods.The MACTAR comprises 2 parts: a transitional part and a status part. Content validity was investigated by comparing patient-elicited activities to items on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Medical Outcomes Study Short-Form 36 (SF-36). Construct validity was determined by correlating MACTAR outcomes with WOMAC/S

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Wang, Qingyi, Zhigang Zhao, Xiaotuo Zhang, et al. "Identifying microRNAs and Their Editing Sites in Macaca mulatta." Cells 8, no. 7 (2019): 682. http://dx.doi.org/10.3390/cells8070682.

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MicroRNAs (miRNAs) are small non-coding RNAs that are critical in post-transcriptional regulation. Macaca mulatta is an important nonhuman primate that is often used in basic and translational researches. However, the annotation of miRNAs in Macaca mulatta is far from complete, and there are no reports of miRNA editing events in Macaca mulatta, although editing may affect the biogenesis or functions of the miRNAs. To improve miRNA annotation and to reveal editing events of miRNAs in Macaca mulatta, we generated 12 small RNA profiles from eight tissues and performed comprehensive analysis of th

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GONZÁLEZ–VÉLEZ, VIRGINIA, and HORACIO GONZÁLEZ–VÉLEZ. "PARALLEL STOCHASTIC SIMULATION OF MACROSCOPIC CALCIUM CURRENTS." Journal of Bioinformatics and Computational Biology 05, no. 03 (2007): 755–72. http://dx.doi.org/10.1142/s0219720007002679.

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This work introduces MACACO, a macroscopic calcium currents simulator. It provides a parameter-sweep framework which computes macroscopic Ca 2+ currents from the individual aggregation of unitary currents, using a stochastic model for L-type Ca 2+ channels. MACACO uses a simplified 3-state Markov model to simulate the response of each Ca 2+ channel to different voltage inputs to the cell. In order to provide an accurate systematic view for the stochastic nature of the calcium channels, MACACO is composed of an experiment generator, a central simulation engine and a post-processing script compo

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PISKORZ, MAŁGORZATA, ALEKSANDRA ZIELIŃSKA, AGATA JÓZEFIAK, AGATA TARKA, WITOLD KĘDZIA, and TOMASZ OPALA. "Knowledge about prophylaxis of cervical cancer in women participating in cytologic cervical cancer screening program." PRZEGLĄD GINEKOLOGICZNO-POŁOŻNICZY 5, no. 3-3 (2005): 141–43. http://dx.doi.org/10.1066/s10014050018.

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11

Shiao, Ming-Hua, Chou-Pu Lai, Bo-Huei Liao, and Yung-Sheng Lin. "Effect of Photoillumination on Gold-Nanoparticle-Assisted Chemical Etching of Silicon." Journal of Nanomaterials 2018 (August 28, 2018): 1–5. http://dx.doi.org/10.1155/2018/5479605.

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Metal-assisted chemical etching (MacEtch) has attracted considerable attention for its ability to fabricate micro- and nanostructures with high aspect ratios and its applications in other microelectromechanical fields. However, few studies have reported the effect of photoillumination on MacEtch. In this study, gold nanoparticles (GNPs) were deposited on the surface of a Si wafer by using the fluoride-assisted galvanic replacement reaction, and then, the effect of photoillumination on the MacEtch of the Si wafer was investigated. The etched depth increased linearly with etching time from 0–45

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Alemo Munters, Li, Ronald F. van Vollenhoven, and Helene Alexanderson. "Patient Preference Assessment Reveals Disease Aspects Not Covered by Recommended Outcomes in Polymyositis and Dermatomyositis." ISRN Rheumatology 2011 (April 12, 2011): 1–5. http://dx.doi.org/10.5402/2011/463124.

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Objectives. Polymyositis (PM) and dermatomyositis (DM) are characterized by impaired muscle function with a majority of patients developing sustained disability. The aim of this study was to evaluate the patient’s individual priorities (patient preference) of disabilities most important to improve in PM/DM using the MacMaster Toronto Arthritis Patient Preference Disability Questionnaire (MACTAR), to correlate the MACTAR to myositis outcomes and to evaluate its test-retest reliability. Methods. Twenty-eight patients with PM/DM performed recommended outcomes as well as the MACTAR, which was perf

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Müller, Simone, Tjebo F. C. Heeren, Roberto Bonelli, et al. "Contrast sensitivity and visual acuity under low light conditions in macular telangiectasia type 2." British Journal of Ophthalmology 103, no. 3 (2018): 398–403. http://dx.doi.org/10.1136/bjophthalmol-2017-311785.

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Background/AimMacular pigment optical density (MPOD) is centrally depleted early on in macular telangiectasia type 2 (MacTel). Contrast sensitivity (CS) might be related to MPOD, and thus impaired in early MacTel. The effect of low luminance was assessed on both CS and best corrected visual acuity (BCVA).MethodsThis is a cross-sectional study. Pelli-Robson charts were used for CS testing at 1 m in photopic (110 lux) and mesopic (1 lux) conditions. BCVA was tested with ETDRS charts and low luminance visual acuity (LLVA) with a 2.0 log unit neutral density filter. MPOD was obtained with dual-wav

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Kobelt, Dennis, Daniel Perez-Hernandez, Claudia Fleuter, et al. "The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis." Oncogene 40, no. 34 (2021): 5286–301. http://dx.doi.org/10.1038/s41388-021-01917-z.

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AbstractCancer metastasis causes >90% of cancer deaths and remains a major treatment challenge. Here we deciphered the impact of tyrosine phosphorylation of MACC1, a causative driver for cancer metastasis, for cancer cell signaling and novel interventions to restrict cancer metastasis. We identified MACC1 as new MEK1 substrate. MEK1 directly phosphorylates MACC1, leading to accelerated and increased ERK1 activation. Mutating in silico predicted hierarchical MACC1 tyrosine phosphorylation sites abrogates MACC1-induced migration, invasion, and MET expression, a transcriptional MACC1 target. T

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Jakiel, Grzegorz, Aneta Słabuszewska-Jóźwiak, Magdalena Czekańska-Rawska, Wojciech Rawski, Arkadiusz Baran, and Małgorzata Bińkowska. "Will uterine fibroids be operated less frequently?" Menopausal Review 4 (2013): 328–32. http://dx.doi.org/10.5114/pm.2013.37850.

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Aversi-Ferreira, Tales Alexandre, Emmanuel Freitas-Ferreira, Roqueline A. G. M. F. Aversi-Ferreira, et al. "Comparative Gross Anatomy of the Forelimb Arteries of the Japanese Monkey (Macaca fuscata) and a Comparative Pattern of Forelimb Arterial Distribution in Primates." BioMed Research International 2020 (July 16, 2020): 1–16. http://dx.doi.org/10.1155/2020/8635917.

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Macaca fuscata displays characteristic behaviours, such as stone handling, locomotor behaviour, gait position, and intermittent bipedalism. Differences in characteristic behaviours among primate species/genera could be explained by anatomical details of the body. However, the anatomical details have not been well studied in Macaca fuscata. Arterial models could be one of the anatomical bases for the phylogenetic and functional differences among species, since the arterial supply could be associated with the muscular performance, especially locomotor behaviour. In this study, five thoracic limb

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Watzke, Robert C. "MacTel 2." Ophthalmology 118, no. 10 (2011): 2098. http://dx.doi.org/10.1016/j.ophtha.2011.05.031.

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18

Symonds, Lynn Katherine, Kelsey K. Baker, Mary Weber Redman, et al. "MACC1 expression as a candidate prognostic biomarker in colorectal cancer patients receiving adjuvant oxaliplatin-based therapy." Journal of Clinical Oncology 37, no. 4_suppl (2019): 567. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.567.

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567 Background: MACC1, part of the HGF-MET pathway, drives proliferation and regulation of MET expression in vitro. In vivo, MACC1 is associated with tumor progression and studies suggest greater MACC1 expression is associated with resistance to platinum-based chemotherapy. We hypothesized that MACC1 may be a prognostic biomarker in colorectal cancer (CRC). Methods: MACC1 expression was evaluated by immunohistochemistry on tumor microarrays (N = 428). Patients were stage I-III CRC who received an oxaliplatin-based regimen (either with 5-FU (FOLFOX) or capecitabine (XELOX)) within the HeCOG 6C/

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Imbastari, Francesca, Mathias Dahlmann, Anje Sporbert, et al. "MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer." Cellular and Molecular Life Sciences 78, no. 7 (2021): 3525–42. http://dx.doi.org/10.1007/s00018-020-03734-1.

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AbstractMetastasis Associated in Colon Cancer 1 (MACC1) is a novel prognostic, predictive and causal biomarker for tumor progression and metastasis in many cancer types, including colorectal cancer. Besides its clinical value, little is known about its molecular function. Its similarity to SH3BP4, involved in regulating uptake and recycling of transmembrane receptors, suggests a role of MACC1 in endocytosis. By exploring the MACC1 interactome, we identified the clathrin-mediated endocytosis (CME)-associated proteins CLTC, DNM2 and AP-2 as MACC1 binding partners. We unveiled a MACC1-dependent r

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Hagemann, Carsten, Nikolas Neuhaus, Mathias Dahlmann, et al. "Circulating MACC1 Transcripts in Glioblastoma Patients Predict Prognosis and Treatment Response." Cancers 11, no. 6 (2019): 825. http://dx.doi.org/10.3390/cancers11060825.

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Glioblastoma multiforme is the most aggressive primary brain tumor of adults, but lacks reliable and liquid biomarkers. We evaluated circulating plasma transcripts of metastasis-associated in colon cancer-1 (MACC1), a prognostic biomarker for solid cancer entities, for prediction of clinical outcome and therapy response in glioblastomas. MACC1 transcripts were significantly higher in patients compared to controls. Low MACC1 levels clustered together with other prognostically favorable markers. It was associated with patients’ prognosis in conjunction with the isocitrate dehydrogenase (IDH) mut

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Jaisankar, Durgasri, Harshal Gondhale, Jay Chhablani, Manisha Agarwal, and Rajiv Raman. "Funduscopic and Angiographic Characteristics in Early and Late Macular Telangiectasia Type 2." Journal of VitreoRetinal Diseases 1, no. 6 (2017): 372–78. http://dx.doi.org/10.1177/2474126417726859.

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Purpose: To report the morphological and vascular characteristics using funduscopic and angiographic features in different cohort as stratified by stages of macular telangiectasia type 2 (MacTel 2). Methods: A cross-sectional, multicentered study of 149 eyes (75 patients) with MacTel 2 was done. The eyes were divided into 2 groups: early group which includes eyes with stages 1 (40 eyes), 2 (41 eyes), and 3 (32 eyes) of MacTel 2 and late group which includes eyes with stages 4 (13 eyes) and 5 (23 eyes) of MacTel 2. The morphological and vascular characteristics on fundus examination and fluores

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Schmidt, Debra A., Monty S. Kerley, Ingrid J. Porton, et al. "FIBER DIGESTIBILITY BY BLACK LEMURS (EULEMUR MACACO MACACO)." Journal of Zoo and Wildlife Medicine 36, no. 2 (2005): 204–11. http://dx.doi.org/10.1638/04-018.1.

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Aldrich, Brooke Catherine, and David Neale. "Pet Macaques in Vietnam: An NGO’s Perspective." Animals 11, no. 1 (2020): 60. http://dx.doi.org/10.3390/ani11010060.

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In this article, we attempt to characterize the widespread trade in pet macaques in Vietnam. Data on confiscations as well as surrenders, releases, and individuals housed at rescue centers across Vietnam for 2015–2019 were opportunistically recorded. Data comparisons between Education for Nature Vietnam and three government-run wildlife rescue centers show that at least 1254 cases of macaque keeping occurred during the study period, including a minimum of 32 Assamese macaques (Macaca assamensis), 158 long-tailed macaques (Macaca fascicularis), 291 Northern pig-tailed macaques (Macaca leonina),

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Ahmad, Kinza T., Joseph Chacko, Ahmed B. Sallam, David B. Warner, and Sami H. Uwaydat. "Surgical Outcomes in Macular Telangiectasia Type 2-Related Macular Holes: A Report on Four Patients." Case Reports in Ophthalmological Medicine 2020 (December 7, 2020): 1–13. http://dx.doi.org/10.1155/2020/8884638.

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Introduction. The few published studies that exist on the surgical outcomes of full-thickness macular hole (FTMH) repair in Macular Telangiectasia (MacTel) Type 2 report poor rates of hole closure of around 30%. This study is the largest case series of patients with FTMH in MacTel Type 2 and describes an 80% hole closure rate. Purpose/Aim. To describe the outcomes of four patients who underwent surgery for FTMH associated with MacTel Type 2. Methods. A retrospective review of clinical, surgical, and imaging data of five eyes in four patients with MacTel Type 2 FTMH who underwent pars plana vit

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Guo, Yuling, Jiuhong Zhong, Fang Wu, and Zhengyu Zhan. "Long noncoding RNA MACC1-AS1 promotes the stemness of hepatocellular carcinoma cells by antagonizing miR-145." Journal of International Medical Research 48, no. 4 (2020): 030006052092041. http://dx.doi.org/10.1177/0300060520920411.

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Objectives This work aimed to investigate the roles of long noncoding (lnc)RNA MACC1-AS1 (MACC1 antisense RNA 1) in progression of hepatocellular carcinoma (HCC). Methods Real-time quantitative PCR, western blot, spheroid formation, aldehyde dehydrogenase isoform 1 (ALDH1) activity analysis, luciferase reporter assay, and RNA pull-down analysis were used to examine MACC1-AS1–mediated effects on HCC cell stemness. Results MACC1-AS1 was highly expressed in HCC tissues and cells. MACC1-AS1 positively regulated the expression of stemness master regulators and inhibited spheroid-forming ability and

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Yao, Yingmin, Chanwei Dou, Zhongtang Lu, Xin Zheng, and Qingguang Liu. "MACC1 Suppresses Cell Apoptosis in Hepatocellular Carcinoma by Targeting the HGF/c-MET/AKT Pathway." Cellular Physiology and Biochemistry 35, no. 3 (2015): 983–96. http://dx.doi.org/10.1159/000369754.

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Background & Aims: To investigate the expression and prognostic value of MACC1 in patients with HCC and identify the mechanism by which MACC1 inhibits HCC cell apoptosis. Methods: MACC1 and p-AKT expression was studied using immunohistochemistry of both HCC tissues and adjacent liver tissues. qRT-PCR and western immunoblotting were used to examine the expression of target genes at the mRNA and protein levels, respectively. The MTT assay was used to assess cell viability, and cell apoptosis was determined by DAPI staining, Annexin V/PI staining and Caspase 3/7 assay. Nude mice were used to

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Yamin, M., Dadi Setiadi, and Khairuddin Khairuddin. "Diet and Behavior of Macaca fascicularis for Ecotourism Contributing on Pengsong Area." Jurnal Biologi Tropis 21, no. 1 (2021): 179. http://dx.doi.org/10.29303/jbt.v21i1.2370.

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Mount Pengsong is a mountainous ecotourism area with beautiful natural scenery and interesting biodiversity, including the presence of Macaca fascicularis populations. Type of food Macaca fascicularis in the tourist area of Mount Pengsong is not yet known, including it’s carrying capacity for population numbers. This study aims to determine the types of plants eaten and the types of food provided by visitors as well as the nutritional content of food consumed by monkeys in the area and the behavior of Macaca fascicularis as a management basis to support ecotourism in Mount Pengsong. Data were

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Lisec, Jan, Dennis Kobelt, Wolfgang Walther, et al. "Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer." Cancers 13, no. 5 (2021): 978. http://dx.doi.org/10.3390/cancers13050978.

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MACC1 is a prognostic and predictive metastasis biomarker for more than 20 solid cancer entities. However, its role in cancer metabolism is not sufficiently explored. Here, we report on how MACC1 impacts the use of glucose, glutamine, lactate, pyruvate and fatty acids and show the comprehensive analysis of MACC1-driven metabolic networks. We analyzed concentration-dependent changes in nutrient use, nutrient depletion, metabolic tracing employing 13C-labeled substrates, and in vivo studies. We found that MACC1 permits numerous effects on cancer metabolism. Most of those effects increased nutrie

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Park, Hee-Won, and Chang-Ik Zhang. "A Population ecological study of the hen clam(Mactra chinensis) in the Dong-li self-regulatory community of Busan." Bulletin of the Korean society of Fisheries Technology 44, no. 2 (2008): 129–40. http://dx.doi.org/10.3796/ksft.2008.44.2.129.

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KLIMEK, RUDOLF. "Iatrogenic causes of cervical cancer in Poland." PRZEGLĄD GINEKOLOGICZNO-POŁOŻNICZY 5, no. 2-2 (2005): 55–59. http://dx.doi.org/10.1066/s10014050004.

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ROKITA, WOJCIECH. "Topography of the cervical intraepithelial neoplasia in women." PRZEGLĄD GINEKOLOGICZNO-POŁOŻNICZY 6, no. 2 (2006): 95–98. http://dx.doi.org/10.1066/s10014060005.

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Lacadena Calero, Juan Ramón. "BIOÉTIC AS MACAQUE-HUMAN CHIMERAS: SCIENTIFIC ASPECTS AND BIOETHICAL REFLECTIONS." Anales de la Real Academia Nacional de Farmacia, no. 87(02) (2021): 117–21. http://dx.doi.org/10.53519/anaesranf.2021.87.02.01.

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The obtention by Izpisua and collaborators (2021) of macaque-human chimeric embryos by microinjection of human pluripotent stem cells into early blastocysts of cynomolgus monkey is described. They studied the competency of human pluripotent stem cells in macaque embryos cultured ex vivo until 19 days post-fertilization. A reflection on these experiments is made from the bioethical point of view.

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Zhang, Chen, Jie An, Woldeab B. Haile, Ramiro Echeverry, Dudley K. Strickland, and Manuel Yepes. "Microglial Low-Density Lipoprotein Receptor-Related Protein 1 Mediates the Effect of Tissue-Type Plasminogen Activator on Matrix Metalloproteinase-9 Activity in the Ischemic Brain." Journal of Cerebral Blood Flow & Metabolism 29, no. 12 (2009): 1946–54. http://dx.doi.org/10.1038/jcbfm.2009.174.

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Studies in animal models of cerebral ischemia indicate that besides its thrombolytic effect, treatment with tissue-type plasminogen activator (tPA) also induces an increase in matrix metalloproteinase-9 (MMP-9) activity in the ischemic tissue associated with the development of cerebral edema. Earlier, we had shown that the low-density lipoprotein receptor-related protein 1 (LRP1) is a substrate for tPA in the brain. In this study, we investigated the effect of the interaction between tPA and microglial LRP1 on MMP-9 activity after middle cerebral artery occlusion (MCAO). We found that exposure

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Song, Hongxin, Ethan A. Rossi, and David R. Williams. "Reduced foveal cone density in early idiopathic macular telangiectasia." BMJ Open Ophthalmology 6, no. 1 (2021): e000603. http://dx.doi.org/10.1136/bmjophth-2020-000603.

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ObjectiveIdiopathic macular telangiectasia (MacTel) is considered primarily a vascular disease affecting juxtafoveal retinal capillaries. However, recent evidence suggests that neuronal changes may occur early in disease development. We used high-resolution adaptive optics retinal imaging to elucidate the foveal cone photoreceptor changes at a cellular level in patients with MacTel.Methods and analysisWe used adaptive optics scanning light ophthalmoscopy (AOSLO) to evaluate the foveal cone photoreceptors in the less-affected eye of patients with asymmetric MacTel. AOSLO images of cone photorec

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Song, Hongxin, Ethan A. Rossi, and David R. Williams. "Reduced foveal cone density in early idiopathic macular telangiectasia." BMJ Open Ophthalmology 6, no. 1 (2021): e000603. http://dx.doi.org/10.1136/bmjophth-2020-000603.

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ObjectiveIdiopathic macular telangiectasia (MacTel) is considered primarily a vascular disease affecting juxtafoveal retinal capillaries. However, recent evidence suggests that neuronal changes may occur early in disease development. We used high-resolution adaptive optics retinal imaging to elucidate the foveal cone photoreceptor changes at a cellular level in patients with MacTel.Methods and analysisWe used adaptive optics scanning light ophthalmoscopy (AOSLO) to evaluate the foveal cone photoreceptors in the less-affected eye of patients with asymmetric MacTel. AOSLO images of cone photorec

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Ali, Dina A., Dina M. El-Guindy, Mohamed A. Elrashidy, et al. "The Prognostic Significance of MACC1 Expression in Breast Cancer and Its Relationship to Immune Cells in the Tumor Microenvironment and Patient Survival." Medicina 57, no. 9 (2021): 934. http://dx.doi.org/10.3390/medicina57090934.

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Breast cancer (BC) is one of the most prevalent malignancies among females worldwide. Globally, distant metastases were reported to be responsible for a large proportion of breast cancer-related deaths. The metastasis-associated colon cancer-1 (MACC1) gene was reported as a reliable biomarker for early detection of metastasis and prediction of prognosis of breast cancer. This study investigated the prognostic significance of MACC1 in breast cancer in relation to the clinicopathologic characteristics and patients’ survival. Furthermore, the possible correlation between MACC1 expression and the

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Zhang, Zheying, Huijie Jia, Yuhang Wang, Baoshun Du, and Jiateng Zhong. "Association of MACC1 expression with lymphatic metastasis in colorectal cancer: A nested case-control study." PLOS ONE 16, no. 8 (2021): e0255489. http://dx.doi.org/10.1371/journal.pone.0255489.

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MACC1 gene is a newly discovered gene and plays an important role in the metastasis of colorectal cancer (CRC). The objective of this study was to investigate whether MACC1 is an independent factor associated with lymphatic metastasis in CRC patients. We analyzed the association between MACC1 expression and lymphatic metastasis in a nested case-control study including 99 cases and 198 matched controls in CRC patients, assessed from August 2001 to March 2015. Cases were defined as lymphatic metastasis and non-lymphatic metastasis according to AJCC TNM stages; for each case, two age-matched cont

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Hasegawa, Hideo, Hiroshi Sato, and Harumi Torii. "Redescription of Enterobius (Enterobius) macaci Yen, 1973 (Nematoda: Oxyuridae: Enterobiinae) Based on Material Collected from Wild Japanese Macaque, Macaca fuscata (Primates: Cercopithecidae)." Journal of Parasitology 98, no. 1 (2012): 152–59. http://dx.doi.org/10.1645/ge-2867.1.

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Fan, Xiaobo, Alongkoad Tanomtong, Arunrat Chaveerach, et al. "High resolution karyotype of thai crab-eating macaque (Macaca fascicularis)." Genetika 46, no. 3 (2014): 877–82. http://dx.doi.org/10.2298/gensr1403877f.

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Comparative chromosome banding analysis and/or fluorescence in situ hybridization (FISH) studies are established approaches to compare human and ape chromosomes. FISH-banding is a relatively new and not routinely applied method suited very well to provide to a better understanding of the evolutionary history of primate and human phylogeny. Here multicolor banding (MCB) applying probes derived from Homo sapiens was used to analyze the chromosomes of Thai crab-eating macaque (Macaca fascicularis). The results agree with those of previous studies in other macaques, e.g. Macaca sylvanus or Macaca

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Li, Jing, Zhenxin Fan, Tianlin Sun, Changjun Peng, Bisong Yue, and Jing Li. "Comparative Genome-Wide Survey of Single Nucleotide Variation Uncovers the Genetic Diversity and Potential Biomedical Applications among Six Macaca Species." International Journal of Molecular Sciences 19, no. 10 (2018): 3123. http://dx.doi.org/10.3390/ijms19103123.

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Macaca is of great importance in evolutionary and biomedical research. Aiming at elucidating genetic diversity patterns and potential biomedical applications of macaques, we characterized single nucleotide variations (SNVs) of six Macaca species based on the reference genome of Macaca mulatta. Using eight whole-genome sequences, representing the most comprehensive genomic SNV study in Macaca to date, we focused on discovery and comparison of nonsynonymous SNVs (nsSNVs) with bioinformatic tools. We observed that SNV distribution patterns were generally congruent among the eight individuals. Out

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Jin, Yan, Kun Zhou, Wenjing Zhao, et al. "Clinicopathological and prognostic significance of metastasis-associated in colon cancer-1 in gastric cancer: A meta-analysis." International Journal of Biological Markers 34, no. 1 (2019): 27–32. http://dx.doi.org/10.1177/1724600818813634.

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Background: The gene metastasis-associated in colon cancer-1 (MACC1) has been reported to be overexpressed in diverse human malignancies, and an increasing amount of evidence suggests that its overexpression is associated with the development and progression of many human tumors. However, the prognostic and clinicopathological value of MACC1 in gastric cancer remains inconclusive. Therefore, we conducted this meta-analysis to investigate the effect of positive MACC1 expression on clinicopathological features and survival outcomes in gastric cancer. Methods: Medline, Web of Science, and EMBASE

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Nair, Rohini M., Varsha Prabhu, Radhika Manukonda, Dilip K. Mishra, Swathi Kaliki, and Geeta K. Vemuganti. "Overexpression of metastasis-associated in colon cancer 1 in retinoblastoma." Tumor Biology 42, no. 11 (2020): 101042832097597. http://dx.doi.org/10.1177/1010428320975973.

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Introduction: Metastasis-associated in colon cancer 1 (MACC1), one of the prognostic markers for colonic and other tumours was noted to be overexpressed in retinoblastoma (Rb) Y79 cancer stem cells. This prompted us to evaluate its expression in primary Rb tumour and serum samples with clinicopathologic correlation. The interacting partner, c-MET was also evaluated in primary tumour tissues to explore the activation of MACC1 signaling. Methodology: This study was done following institutional review board approval from participating institutes. Semiquantitative gene expression for MACC1 was eva

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Santiago, Gisele, Lia Rejane Silveira Reiniger, and Joana Graciela Hanauer. "Somaclones em batata identificados pelos descritores mínimos de broto." Ciência Rural 45, no. 8 (2015): 1381–86. http://dx.doi.org/10.1590/0103-8478cr20140557.

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Este estudo objetivou verificar a estabilidade fenotípica das cultivares de batata 'Asterix' e 'Macaca', avaliar o efeito do tipo de explante (organogênese direta e indireta) e do tempo de subcultivo (12 e 70 meses) em meio nutritivo MS sobre a ocorrência de somaclones nas duas cultivares na produção de batata semente, mediante o emprego de sete descritores mínimos de broto. Em 'Asterix' e 'Macaca' ocorreram somaclones em quatro dos sete descritores, contudo, apenas no formato e pubescência da base do broto houve variação, simultaneamente, em ambas. Os dois genótipos são suscetíveis à ocorrênc

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Coudrat, C. N. Z., L. D. Rogers, and K. A. I. Nekaris. "Abundance of primates reveals Samkos Wildlife Sanctuary, Cardamom Mountains, Cambodia as a priority area for conservation." Oryx 45, no. 3 (2011): 427–34. http://dx.doi.org/10.1017/s0030605310001080.

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AbstractWe conducted a primate survey in Samkos Wildlife Sanctuary, western Cambodia, during the wet season in 2009. We visually confirmed the presence of five out of six primate species thought to occur in the area: Bengal slow loris Nycticebus bengalensis, Indochinese silvered langur Trachypithecus germaini, pileated gibbon Hylobates pileatus, pig-tailed macaque Macaca leonina and long-tailed macaque Macaca fascicularis. We did not find any sign of the stump-tailed macaque Macaca arctoides and suggest it is absent in Samkos Wildlife Sanctuary and possibly from the Cardamom Mountains. We prov

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Burton, Frances D., and Leslie Kin Wai Chan. "Notes on the care of long-tail macaque (Macaca fascicularis) infants by stump-tail macaques (Macaca thibetana)." Canadian Journal of Zoology 65, no. 3 (1987): 752–55. http://dx.doi.org/10.1139/z87-115.

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An unusual but sustaining case of interspecific infant care behaviour was observed in June 1985 while an ecological and behavioural study of the macaques was being conducted in the forest of the Kowloon Peninsula, Hong Kong. We describe this specific interaction among three long-tail macaque infants (Macaca fascicularis) and their mothers and two stump-tail macaque (Macaca thibetana) females who acted as "babysitters." The cross-species infant care observed took place in a polyspecific group which also included rhesus monkeys (Macaca mulatta) and hybrids of rhesus and long-tail monkeys. This u

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Choi, Kang-Ho, Ja-Hae Kim, Changho Lee, et al. "Microbleeds and Outcome in Patients With Acute Ischemic Stroke and Atrial Fibrillation Taking Anticoagulants." Stroke 51, no. 12 (2020): 3514–22. http://dx.doi.org/10.1161/strokeaha.120.030300.

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Background and Purpose: We investigated the impact of the presence, burden, and location of cerebral microbleeds (CMBs) on the risk of major adverse cerebrovascular and cardiovascular events (MACCE) in patients with acute ischemic stroke and atrial fibrillation treated with oral anticoagulants (OACs). We also examined whether the clinical effect of CMBs differs according to the type of OACs. Methods: A total of 1742 patients with acute ischemic stroke and atrial fibrillation treated with OACs were enrolled in this cohort study. The primary composite outcome was the occurrence of MACCE (a compo

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Lin, Li, Changqie Pan, Xiaoyin Li, et al. "Escape of gastric cancer cell from metabolic stress via DLC3/MACC1 axis." Journal of Clinical Oncology 35, no. 15_suppl (2017): e15550-e15550. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e15550.

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e15550 Background: Metabolic stress usually occurs in rapidly proliferating cells when energy demand exceeds supply. Interestingly, cancer cells can somehow sustain the stress and get rid of it. The mechanisms remain unclear. Previously we discovered that MACC1 is an oncogene promoting gastric cancer (GC) growth and metastasis. Besides, it is upregulated by metabolic stress and promotes glycolysis [2014 ASCO annual meeting abstract e15054 & Oncogene 2015;34(21)]. In current study, we aim to further discover how it helps GC cell metabolize and metastasis. Methods: MACC1 and its correlated g

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Koch, Richard. "Spending MacTeX funds." TUGboat 42, no. 1 (2021): 92. http://dx.doi.org/10.47397/tb/42-1/tb130koch-mactex.

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Bottini, Alexander R., Barton L. Blackorby, Madelyn Michaels, et al. "Long-Term Outcomes in Macular Telangiectasia Type 2 With Subretinal Neovascularization." Journal of VitreoRetinal Diseases 4, no. 5 (2020): 386–92. http://dx.doi.org/10.1177/2474126420927149.

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Purpose: This work reports long-term outcomes in macular telangiectasia type 2 (MacTel) with subretinal neovascularization (SRNV). Methods: A retrospective, single-center review of medical records was performed on all patients with a diagnosis of MacTel presenting between May 2004 and October 2019. Medical and ocular history, best-corrected visual acuity (BCVA) at baseline and final visit, optical coherence tomography data, and treatment history of SRNV secondary to MacTel were recorded. Results: A total of 471 eyes were diagnosed with MacTel. SRNV was present in 44 eyes (9.3%), of which 38 ey

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Jeong, Hoiseon, Jiyoon Jung, Hwa Eun Oh, et al. "Prognostic Characteristics of MACC1 Expression in Epithelial Ovarian Cancer." BioMed Research International 2018 (November 1, 2018): 1–5. http://dx.doi.org/10.1155/2018/9207153.

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Recent studies have shown that overexpression of metastasis-associated in colon cancer 1 (MACC1) is significantly associated with adverse prognoses of patients with different kinds of cancer. However, the exact survival effect of MACC1 on epithelial ovarian cancer (EOC) patients has not yet been established. Thus, the objective of this study was to explore the prognostic role of MACC1 mRNA in EOC by using Kaplan-Meier (KM) plotter and ONCOMINE database. Our results indicated that MACC1 mRNA high expression was significantly associated with unfavorable overall survival (hazard ratio (HR) = 1.51

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