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Journal articles on the topic 'Macular thickness'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Li, Fan, Yiming Huo, Lihua Ma, et al. "Clinical Analysis of Macular Choroidal Thickness in Pseudoexfoliative Glaucoma and Primary Open-Angle Glaucoma." Journal of Ophthalmology 2021 (November 16, 2021): 1–5. http://dx.doi.org/10.1155/2021/3897952.

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Purpose. To evaluate the differences in macular choroidal thickness and volume among patients with pseudoexfoliative glaucoma (PXG), patients with primary open-angle glaucoma (POAG), and controls. Methods. A total of 50 PXG patients (50 eyes) and 56 POAG patients (56 eyes) were selected as the PXG group and the POAG group, respectively, in this case-control study. A total of 54 age-, gender-, IOP-, and axial length-matched healthy individuals (54 eyes) were selected as the control group. Enhanced-depth imaging-optical coherence tomography (EDI-OCT) was used to measure and analyze the choroidal

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Dikkaya, Funda, and Sevil Karaman Erdur. "Comparison of optical coherence tomography measurements between high hyperopic and low hyperopic children." Therapeutic Advances in Ophthalmology 12 (January 2020): 251584141989981. http://dx.doi.org/10.1177/2515841419899819.

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Purpose: To identify the peripapillary retinal nerve fiber layer, total macular, ganglion cell layer, and inner plexiform layer thicknesses in children with high hyperopia using spectral domain optical coherence tomography. Methods: Twenty-one children with high hyperopia and 20 controls were enrolled in this study. Subjects with spherical equivalent +5.0 D or higher were evaluated in the study group and subject with spherical equivalent between +0.25 and +2.0 D in the control group. The retinal nerve fiber layer thickness, macular thickness, macular ganglion cell layer and inner plexiform lay

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Mohd-Ilham, Ismail, Evelyn Li Min Tai, Hussain Suhaimi, and Ismail Shatriah. "Evaluation of Macular and Retinal Nerve Fiber Layer Thickness in Children with Type 1 Diabetes Mellitus without Retinopathy." Korean Journal of Ophthalmology 35, no. 4 (2021): 287–94. http://dx.doi.org/10.3341/kjo.2020.0106.

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Purpose: There are limited data from Asian countries regarding retinal thickness in children with type 1 diabetes mellitus (T1DM). This study aimed to compare the macular and retinal nerve fiber layer (RNFL) parameters between diabetic children without retinopathy and non-diabetic healthy children. We also evaluated the factors associated with RNFL thickness in children with T1DM.Methods: A comparative cross-sectional study was conducted among children with T1DM and healthy children aged 7 to 17 years old in Hospital Universiti Sains Malaysia from 2017 to 2019. Children with retinal disease or

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Kim, Jin-Soo, Young Kook Kim, Sung Uk Baek, et al. "Topographic correlation between macular superficial microvessel density and ganglion cell-inner plexiform layer thickness in glaucoma-suspect and early normal-tension glaucoma." British Journal of Ophthalmology 104, no. 1 (2019): 104–9. http://dx.doi.org/10.1136/bjophthalmol-2018-313732.

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Background/AimsTo investigate the topographic relationship between macular superficial microvessel density (SMD) and macular ganglion cell-inner plexiform layer (GCIPL) thickness in eyes with glaucoma-suspect (GS) and early normal-tension glaucoma (NTG).MethodsA total of 86 eyes of 86 patients with early NTG (standard automated perimetry mean deviation >−5.5 decibels) and a total of 25 eyes of 25 patients with GS were retrospectively reviewed. All of the subjects underwent optical coherence tomography (OCT) and OCT angiography (OCTA) scan. On the OCTA scan images, macular SMD was analysed b

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Romero-Bascones, David, Unai Ayala, Ane Alberdi, et al. "Spatial characterization of the effect of age and sex on macular layer thicknesses and foveal pit morphology." PLOS ONE 17, no. 12 (2022): e0278925. http://dx.doi.org/10.1371/journal.pone.0278925.

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Characterizing the effect of age and sex on macular retinal layer thicknesses and foveal pit morphology is crucial to differentiating between natural and disease-related changes. We applied advanced image analysis techniques to optical coherence tomography (OCT) to: 1) enhance the spatial description of age and sex effects, and 2) create a detailed open database of normative retinal layer thickness maps and foveal pit shapes. The maculae of 444 healthy subjects (age range 21–88) were imaged with OCT. Using computational spatial data analysis, thickness maps were obtained for retinal layers and

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Kao, Chia-Chen, Hui-Min Hsieh, Yo-Chen Chang, Hui-Chen Chu, Yuan-Han Yang, and Shwu-Jiuan Sheu. "Optical Coherence Tomography Assessment of Macular Thickness in Alzheimer’s Dementia with Different Neuropsychological Severities." Journal of Personalized Medicine 13, no. 7 (2023): 1118. http://dx.doi.org/10.3390/jpm13071118.

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This retrospective case-control study aimed to investigate associations between disease severity of Alzheimer’s dementia (AD) and macular thickness. Data of patients with AD who were under medication (n = 192) between 2013 and 2020, as well as an age- and sex-matched control group (n = 200) with normal cognitive function, were included. AD patients were divided into subgroups according to scores of the Mini-Mental State Examination (MMSE) and Clinical Dementia Rating (CDR). Macular thickness was analyzed via the Early Treatment Diabetic Retinopathy Study (ETDRS) grid map. AD patients had signi

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Geneid, Mohamed I., Janne J. Uusitalo, Ilmari L. Leiviskä, Ville O. Saarela, and M. Johanna Liinamaa. "Relation between retinal vessel diameter and posterior segment optical coherence tomography variables in middle-aged Caucasians: the Northern Finland Birth Cohort Eye Study." British Journal of Ophthalmology 104, no. 10 (2020): 1435–42. http://dx.doi.org/10.1136/bjophthalmol-2019-314803.

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AimsStudying the relationship between retinal vessel diameter (RVD) with (1) macular thickness and volume, (2) retinal nerve fibre layer (RNFL), (3) ganglion cell-inner plexiform layer (GC-IPL) and (4) optic nerve head (ONH) in a population cohort of middle-aged Caucasians.MethodsWe collected data from 3070 individuals. We used a semiautomated computer-assisted programme to measure central retinal arteriolar equivalent and central retinal venular equivalent. Macular and ONH parameters were assessed by optical coherence tomography.ResultsData from 2155 persons were analysed. A larger RVD was as

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Meihong, Zhu, and Lin Tainan. "Changes of retinal thickness in macular area of myopia children." E3S Web of Conferences 292 (2021): 03103. http://dx.doi.org/10.1051/e3sconf/202129203103.

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Objective: To study the changes of macular retinal thickness in children with moderate and low myopia by frequency domain OCT. Methods: 108 school-age children aged 7-12 years were selected and enrolled into the group. Among them, 58 cases (116 eyes) with simple moderate and low myopia in the myopia group and 50 cases (100 eyes) with straight eyes in the emmetropia group. The retinal thickness in different parts of macular area was compared between the two groups, and the correlation between retinal thickness in different parts of macular area and diopter and axial length was analyzed by Pears

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Niyazmand, Hamed, Gareth Lingham, Paul G. Sanfilippo, et al. "The effect of transverse ocular magnification adjustment on macular thickness profile in different refractive errors in community-based adults." PLOS ONE 17, no. 4 (2022): e0266909. http://dx.doi.org/10.1371/journal.pone.0266909.

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Purpose Changes in retinal thickness are common in various ocular diseases. Transverse magnification due to differing ocular biometrics, in particular axial length, affects measurement of retinal thickness in different regions. This study evaluated the effect of axial length and refractive error on measured macular thickness in two community-based cohorts of healthy young adults. Methods A total of 2160 eyes of 1247 community-based participants (18–30 years; 23.4% myopes, mean axial length = 23.6mm) were included in this analysis. Macular thickness measurements were obtained using a spectral-d

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Fernández-Buenaga, Roberto, Gema Rebolleda, Francisco J. Muñoz-Negrete, Inés Contreras, and Pilar Casas-Llera. "Macular Thickness." Ophthalmology 116, no. 8 (2009): 1587–1587. http://dx.doi.org/10.1016/j.ophtha.2009.02.028.

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Shen, Ling, Fei Gao, Zhong Lin, et al. "Children macular thickness correlated with mother macular thickness." Acta Ophthalmologica 95, no. 6 (2016): e512-e514. http://dx.doi.org/10.1111/aos.13065.

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Edwin, Megha, Remya Raghavan, and Mahadevan K. "A retrospective observational study on changes in macular thickness with age in normal population using spectral-domain optical coherence tomography." International Journal of Research in Medical Sciences 11, no. 5 (2023): 1563–67. http://dx.doi.org/10.18203/2320-6012.ijrms20231316.

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Background: The aim of this study was to determine the changes in macular thickness with age, by SD-OCT and to estimate the inner and outer retinal layer thickness of outer and inner macula based on different zones and to assess their relationship with age. Methods: A retrospective observational study of 50 subjects with age ranging from 21 to 60 years was studied with SD-OCT (10 mm scan). The study was done in the month of April 2021 at Department of Ophthalmology, Sree Gokulam Medical College and Research Foundation. Results: Total macular thickness ranged from 180 to 225 micrometer with no

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Chung, Yeon Woong, Moon Young Choi, Jung-sub Kim, and Jin-woo Kwon. "The Association between Macular Thickness and Axial Length in Myopic Eyes." BioMed Research International 2019 (July 16, 2019): 1–7. http://dx.doi.org/10.1155/2019/8913582.

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Purpose. To investigate the relationship between macular thickness and axial length (AL) in myopic eyes. Methods. We included 441 myopic eyes in this study and measured macular thickness at the fovea and in other macular regions, using optical coherence tomography. We got thickness difference indices (TDIs) which by definition are the values of thickness difference obtained by subtracting the foveal thickness from that of each macula sector to evaluate macular contour. We then analyzed the relationships between AL and foveal thickness and AL and the TDIs of each macular sector. Results. In pol

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Li, Fan, Yiming Huo, Lihua Ma, and Guangxian Tang. "Correlation Analysis between Macular Choroidal Thickness and Visual Field Mean Defect in Primary Open-Angle Glaucoma." Journal of Ophthalmology 2021 (April 8, 2021): 1–6. http://dx.doi.org/10.1155/2021/5574950.

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Purpose. To evaluate the differences in macular choroidal thickness and volume between patients with primary open-angle glaucoma (POAG) and healthy controls to assess the correlation between macular choroidal thickness and visual field mean defect (MD). Methods. Case-control study. A total of 101 patients (101 eyes) with POAG who were hospitalized in our hospital and 102 healthy subjects (102 eyes) matched by age, sex, and axial length were consecutively selected as the POAG group and the control group, respectively. The macular choroidal thickness and volume in nine regions were measured in a

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Saha, Mita, Sabyasachi Bandyopadhyay, Debabrata Das, and Sourav Ghosh. "Comparative analysis of macular and peripapillary retinal nerve fiber layer thickness in normal, glaucoma suspect and glaucomatous eyes by optical coherence tomography." Nepalese Journal of Ophthalmology 8, no. 2 (2017): 110–18. http://dx.doi.org/10.3126/nepjoph.v8i2.16991.

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Introduction: Peripapillary retinal nerve fiber layer (RNFL) thickness analysis is a subjective method of analysis of glaucomatous damage. As almost 50% of retinal ganglion cells are located in the macula, assessment of macular thickness can be an alternative method for diagnosis of glaucoma. Objectives: To evaluate the changes in macular and retinal nerve fiber layer thickness in controls, glaucoma suspects and glaucoma patients using time domain optical coherence tomography (TD-OCT). Materials and methods: Macular and peripapillary RNFL scans were performed in one eye of 70 controls, 35 glau

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Kim, Ko Eun, and Ki Ho Park. "Macular imaging by optical coherence tomography in the diagnosis and management of glaucoma." British Journal of Ophthalmology 102, no. 6 (2017): 718–24. http://dx.doi.org/10.1136/bjophthalmol-2017-310869.

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The macular area is important to the detection of glaucomatous retinal ganglion cell (RGC) damage. Macular thickness complementary to peripapillary retinal nerve fibre layer (RNFL) thickness can well reflect glaucomatous damage, given that the macula contains more than 50% of the RGCs in a multilayered pattern and larger RGC bodies compared with their axons. Thus, macular ganglion cell thickness parameters recently have been considered to be an effective glaucoma-diagnostic tool comparable to RNFL thickness parameters. Furthermore, spectral-domain optical coherence tomography ganglion cell–inn

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Šiško, Katarina, Nina Knez, and Dušica Pahor. "Influence of cataract surgery on retinal thickness." Acta Medico-Biotechnica 3, no. 2 (2021): 52–61. https://doi.org/10.18690/actabiomed.41.

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Purpose: We evaluated the potential influence of cataract surgery on macular thickness and on the thickness of the retinal nerve fibre layer (RNFL) at different time intervals within 1 month after surgery. Methods: This prospective study involved 27 patients (27 eyes) scheduled for ambulatory cataract surgery with phacoemulsification and intraocular lens implantation. Optical coherence tomography was used to measure macular thickness, macular volume and RNFL thickness on operated eyes on the day before surgery and 1, 14 and 30 days after surgery. Contralateral non-operated eyes served as a con

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Dr., Nitisha Bhimavarapu, and M. Parni Kumar Dr. "Alterations in Thickness of Macula after Uncomplicated Cataract Surgery." International Journal of Innovative Science and Research Technology (IJISRT) 9, no. 2 (2024): 14. https://doi.org/10.5281/zenodo.10696581.

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Purpose Evaluate alterations in thickness of macula after uncomplicated cataract surgery, to clarify the optical tomographic characteristics of thickness of macula after uncomplicated cataract surgery, and also compare the changes in thickness of macula after uncomplicated phacoemulsification and manual small incision cataract surgery.  Patients and Methodology The study included a cohort of fifty patients, consisting of 28 males and 22 females. The age range of the participants was between 35 and 78 years, with a mean age of 58.6 years. Out of the total, 25 individuals (50%) underwent small

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Uma, Thakur, Mishra Pooja, Gupta Priyanka, and Chourasia Hemlata. "To Analyse Macular Thickness by Age and Gender in Age Group 18-30 Years." International Journal of Pharmaceutical and Clinical Research 14, no. 11 (2022): 29–32. https://doi.org/10.5281/zenodo.13255164.

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<strong>Background & Method: </strong>The aim of this study is to analyse macular thickness by age and gender in age group 18-30 years. Patients who presented to our department with various complaints was examined thoroughly and those found relevant are to be included in our study. After routine registration of the selected cases the examination was done keeping following points in to the consideration. <strong>Result:</strong> In table male and female macular thickness has been depicted in age group 18-30 years. The male macular thickness is 244.32 (±19.22) compared

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Sorokin, E. L., L. V. Bushnina, and I. E. Pashentsev. "Morphometric state of the macular zone in atrophic form of myopic maculopathy." Modern technologies in ophtalmology, no. 2 (April 13, 2022): 140–46. http://dx.doi.org/10.25276/2312-4911-2022-2-140-146.

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Purpose. Clinical assessment of morphometric parameters of the macular zone in patients with atrophic myopic maculopathy, their relationship with age and size of the anteroposterior axis (APA) of the eyes. Material and methods. The main group consisted of 143 patients (286 eyes) with acquired axial myopia with complications in the posterior pole of the eye. It identifies 3 subgroups according to the severity of myopic macular changes. The comparison group included 34 patients (68 eyes) with acquired uncomplicated axial myopia. Control group – 13 people (26 eyes) with emmetropic refraction with

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Shahid, Muhammad Hamza, Faisal Rashid, Saba Tauqeer, Rabab Ali, Muhammad Talha Farooq, and Nouman Aleem. "Comparison of Suprachoroidal Triamcinolone Injection with Intravitreal Bevacizumab Vs Intravitreal Bevacizumab only in Treatment of Refractory Diabetic Macular Edema." Pakistan Journal of Medical and Health Sciences 16, no. 6 (2022): 301–3. http://dx.doi.org/10.53350/pjmhs22166301.

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Background: Macular edema due to diabetic retinopathy is among the most common causes of blindness in diabetics from working age group around the world . Diabetic macular edema which involves the center of the macula is among the major cause of visual decline in patients with diabetes mellitus. Intra-Vitreal Triamcinolone Acetonide with intravitreal Bevacizumab and intravitreal Bevacizumab only have been in practice as treatment options for cases not responsive to anti-vascular endothelial growth factor agents. Objective: To compare safety and efficacy profile of suprachoroidal injection of tr

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Jabbar, Bushra, Qamar Ul Islam, Muhammad Kashif Hanif, Ubaidullah Yasin, Omer Farooq, and Saman Fatima. "SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS." Pakistan Armed Forces Medical Journal 70, no. 6 (2020): 1804–09. http://dx.doi.org/10.51253/pafmj.v70i6.4040.

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Objective: To determine the thicknesses of retinal nerve fiber layer (RNFL) and macula by fourier-domain (FD)optical coherence tomography (OCT) in diabetic patients with end-stage renal failure (ESRF) undergoinghemodialysis. Study Design: Cross-sectional study. Place and Duration of Study: Pakistan Naval Ship, Shifa Karachi, from Jan 2019 to Jul 2019 Methodology: Fifty four patients presenting to nephrology department who met the inclusion criteria wereincluded in the study. Macular and retinal nerve fibre layer thicknesses were compared pre and post 30 minutesof hemodialysis

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Zhang, Peng, Qingli Shang, Jingxue Ma, Yuhua Hao, and Cunxi Ye. "Correlation between Postoperative Area of High Autofluorescence in Macula and Visual Acuity after Macular Hole Closure." European Journal of Ophthalmology 27, no. 6 (2017): 781–85. http://dx.doi.org/10.5301/ejo.5000953.

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Purpose To determine the correlation between the preoperative basal diameter of macular hole, the postoperative area of high autofluorescence (AF) in macula, and visual acuity in full-thickness macular hole. Methods Forty-nine patients with full-thickness macular hole who underwent vitrectomy and C3F8 filling were reviewed. The preoperative diameter of macular hole, the 6 months postoperative area of high AF in macula if it existed, the length of inner segment/outer segment (IS/OS) defect, and visual acuity were obtained. The correlation between them was determined. Results At postoperative 6

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Kwon, Jin-woo, Jin A. Choi, Jung-sub Kim та Tae Yoon La. "Ganglion Cell-Inner Plexiform Layer, Peripapillary Retinal Nerve Fiber Layer, and Macular Thickness in Eyes with Myopicβ-Zone Parapapillary Atrophy". Journal of Ophthalmology 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/3746791.

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Purpose. To assess the correlations of myopicβ-zone parapapillary atrophy (β-PPA) with the optic nerve head (ONH) and retina.Methods. We selected 27 myopic patients who showed prominentβ-PPA in one eye and noβ-PPA in the other eye. We studied their macula, macular ganglion cell-inner plexiform layer (mGCIPL), peripapillary retinal nerve fiber layer (pRNFL) thickness, and ONH parameters using optical coherence tomography.Results. The average of five out of six sectors and minimum values of mGCIPL thicknesses in eyes with prominentβ-PPA discs were significantly less than those of the control eye

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Lever, Mael, Ying Chen, Moritz Glaser, et al. "Microvascular and Morphologic Changes of the Macula over Lifetime." Life 12, no. 4 (2022): 568. http://dx.doi.org/10.3390/life12040568.

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In ocular, neurologic, and cardiovascular diseases, macular segmentation data from spectral-domain optical coherence tomography (SD-OCT) provide morphologic, and OCT-angiography (OCTA) results give microvascular information about the macula. Age was shown to influence both methods’ measurements. To further characterize this association, macular SD-OCT and OCTA changes were investigated in a population of juvenile, adult, and older individuals. Macular segment thickness and superficial (SCP) and deep plexus (DCP) vascular density (VD) of 157 healthy individuals aged 10–79 years were analyzed re

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Rao, Evangeline, Maithili Mishra, Sheela Kerkar, and Arjun Ahuja. "Correlation of Optical Coherence Tomographic Findings with Clinical Features in High Myopia." International Journal of Recent Surgical and Medical Sciences 05, no. 01 (2019): 019–25. http://dx.doi.org/10.1055/s-0039-1689063.

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AbstractThis is a cross-sectional observational study to correlate relationship between macular and retinal nerve fiber layer (RNFL) thickness in relation to clinical features in high myopia. A total of 100 eyes of 50 consecutive patients underwent optical coherence tomography (OCT) of the macula and RNFL. It was observed that correlation of RNFL thickness to the axial length is better than that of RNFL thickness to the spherical equivalent. The macular thickness in the parafoveal region was observed to be thicker than the perifoveal region in all quadrants. This study therefore emphasizes the

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Zhao, Minghui, Qiang Wu, Ping Hu, and Lili Jia. "Macular Thickness Assessed with Optical Coherence Tomography in Young Chinese Myopic Patients." Journal of Ophthalmology 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/715798.

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Purpose.To evaluate the variations in macular thickness in young Chinese myopic persons and the association with axial length (AL), spherical equivalence refraction (SE), age, intraocular pressure, and sex.Methods.In total, 133 young Chinese myopic subjects between 18 and 30 years of age were selected. The macular thickness was assessed using third-generation optical coherence tomography. AL, intraocular pressure, and SE were also measured.Results.The mean central foveal thickness was191.1±15.3 µm. The macula was consistently thinner in women than in men. Central foveal thickness had a signifi

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Lever, Mael, Christian Halfwassen, Jan Darius Unterlauft, Nikolaos E. Bechrakis, Anke Manthey, and Michael R. R. Böhm. "The Paediatric Glaucoma Diagnostic Ability of Optical Coherence Tomography: A Comparison of Macular Segmentation and Peripapillary Retinal Nerve Fibre Layer Thickness." Biology 10, no. 4 (2021): 260. http://dx.doi.org/10.3390/biology10040260.

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Paediatric glaucoma leads to a decreased thickness of the peripapillary retinal nerve fibre layer (pRNFL) and of the macula. These changes can be precisely quantified using spectral domain-optical coherence tomography (SD-OCT). Despite abundant reports in adults, studies on the diagnostic capacity of macular SD-OCT in paediatric glaucoma are rare. The aim of this study was to compare the glaucoma discriminative ability of pRNFL and macular segment thickness in paediatric glaucoma patients and healthy children. Data of 72 children aged 5–17 years (glaucoma: 19 (26.4%), healthy: 53 (73.6%)) exam

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Cho, Joon Hee, So Hyun Bae, Ha Kyoung Kim, and Young Joo Shin. "Optical Quality Assessment in Patients with Macular Diseases Using Optical Quality Analysis System." Journal of Clinical Medicine 8, no. 6 (2019): 892. http://dx.doi.org/10.3390/jcm8060892.

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Macular diseases cause vision loss, as the macula is the functional center for vision. In this study we assessed optical quality in eyes with macular diseases and evaluated the effectiveness of the Optical Quality Analysis System (OQAS) to detect macular diseases. We analyzed 88 eyes of 88 patients with macular diseases (51 men and 37 women; mean age: 65.24 ± 12.96 years) and 43 eyes of 43 control subjects (11 men and 32 women; mean age: 54.70 ± 15.03 years). The macular diseases included age-related macular disease (n = 62), diabetic macular edema (n = 19), and retinal vein occlusion (n = 7).

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Qiu, Kunliang, Binyao Chen, Jianling Yang, et al. "Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects." British Journal of Ophthalmology 103, no. 6 (2018): 821–25. http://dx.doi.org/10.1136/bjophthalmol-2018-312162.

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PurposeTo determine the influence of the optic disc–fovea distance (DFD) on the normative classifications based on thickness measurements of macular inner retinal layers with spectral-domain optical coherence tomography (OCT) in healthy subjects.MethodsA total of 182 eyes from 182 healthy subjects were included (mean (SD) spherical equivalent −0.8 (1.9) dioptres). We performed macula and optic disc imaging with the Topcon 3D OCT 2000. The thickness of the macular inner retinal layers (macular retinal nerve fibre layer (mRNFL), ganglion cell-inner plexiform layer (GCIPL) and both combined (gang

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Souza-Júnior, José Edvan de, Carlos Alexandre de Amorim Garcia, Elvira Maria Mafaldo Soares, Técia Maria Oliveira Maranhão, Telma Maria Araújo Moura Lemos, and George Dantas Azevedo. "Polycystic Ovary Syndrome: Aggressive or Protective Factor for the Retina? Evaluation of Macular Thickness and Retinal Nerve Fiber Layers Using High-Definition Optical Coherence Tomography." Journal of Ophthalmology 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/193078.

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Objective. To compare macular thickness (MT) and retinal nerve fiber layers (RNFL) between women with polycystic ovary syndrome (PCOS) and healthy women.Materials and Methods. The study included 45 women with PCOS and 47 ovulatory women undergoing clinical-gynecological and ophthalmic evaluations, including measurement of MT, RNFL, and optic disc parameters using optical coherence tomography.Results. The superior RNFL around the optic nerve was significantly thicker in PCOS than in healthy volunteers (P=0.036). After stratification according to insulin resistance, the temporal inner macula (TI

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Delfi, Delfi, Vanda Virgayanti, and Julham Alandy. "Macular Alteration of Topical Diclofenac Sodium after Phacoemulsification Surgery in Diabetic Patients." Open Access Macedonian Journal of Medical Sciences 9, T3 (2021): 156–59. http://dx.doi.org/10.3889/oamjms.2021.6287.

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BACKGROUND: Cystoid macular edema (CME) is a serious complication of cataract surgery in a diabetic patient. CME was found 1–19% after phacoemulsification surgery. Nonsteroidal anti-inflammatory drugs inhibit cyclooxygenase-1, cyclooxygenase-2, and endoperoxides. Inhibition of these enzymes also reduces macular thickening. AIM: The aim of the study was to assess macular thickness alteration after application of 1.00 mg diclofenac sodium eye drops in diabetic patients who receive phacoemulsification surgery. METHODS: This study was a quasi-experimental study. A total of 40 eyes diabetic retinop

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Koman-Wierdak, Edyta, Joanna Róg, Agnieszka Brzozowska, et al. "Analysis of the Peripapillary and Macular Regions Using OCT Angiography in Patients with Schizophrenia and Bipolar Disorder." Journal of Clinical Medicine 10, no. 18 (2021): 4131. http://dx.doi.org/10.3390/jcm10184131.

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Purpose: To measure RNFL and vasculature around the optic disc and in the macula in patients with schizophrenia (SZ) and bipolar disorder (BD) using optical coherence tomography angiography (OCTA). Methods: 24 eyes of patients with SZ and 16 eyes of patients with BD as well as 30 eyes of healthy subjects were examined with OCTA. The radiant peripapillary capillary (RPC) density and RNFL thickness were measured in the peripapillary area. Moreover, macular thickness and vessel density were measured in both superficial and deep layers. Results: Significantly decreased values of vessel density in

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Alizadeh, Yousef, Maryam Dourandeesh, Hassan Behboudi, Shila Kianmehr, Ehsan Kazemnezhad leyli, and Nooshin Nimasa. "Repeatability and Reproducibility of Macular Thickness Measurements Using Optical Coherence Tomography (OCT) in Normal Eyes Before and After Pupil Dilation." Journal of Guilan University of Medical Sciences 31, no. 3 (2022): 180–91. http://dx.doi.org/10.32598/jgums.31.3.1911.1.

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Background Optical coherence tomography (OCT) is one of the most valuable imaging techniques in the evaluation of macula. The repeatability and reproducibility of OCT are of crucial importance in reassuring this tool’s efficacy in evaluating the structure of the retina. Objective This study aims to investigate the repeatability and reproducibility of OCT in measuring the macular thickness in normal eyes before and after pupil dilation. Methods A total of 44 eyes of healthy individuals in the age range of 20 to 50 years were employed for the measurement of macular thickness in the central 6 mm

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Tao, Yuan, Chao Huang, Min Liu, et al. "Short-term effect of intravitreal conbercept injection on major and macular branch retinal vein occlusion." Journal of International Medical Research 47, no. 3 (2019): 1202–9. http://dx.doi.org/10.1177/0300060518819613.

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Objective To evaluate the effectiveness of intravitreal conbercept injection on major and macular branch retinal vein occlusion (BRVO). Methods This retrospective analysis involved 43 patients with BRVO (major BRVO n = 24; macular BRVO, n = 19) who were diagnosed by fluorescein fundus angiography (FFA) and injected with intravitreal conbercept. The following outcomes were measured at baseline and follow-up (1-6 months): best-corrected visual acuity (BCVA), central foveal thickness (CFT), total retinal volume in a 6-mm diameter section of the macula, choroidal thickness under the central fovea

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Kumar, Amrendra, Vidya Bhushan Kumar, and Anita Ambastha. "A Prospective Study on Macular Thickness Changes Following Uncomplicated Cataract Surgery in Diabetic Patients Using OCT." International Journal of Medical and Biomedical Studies 9, no. 1 (2025): 96–101. https://doi.org/10.32553/ijmbs.v9i1.2956.

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Background: Cataract surgery in diabetic patients often results in postoperative changes in macular thickness, potentially impacting visual recovery. Optical Coherence Tomography (OCT) provides a reliable means to monitor these changes. While previous studies suggest a temporary thickening of the macula after surgery, the extent and clinical significance of these changes remain unclear. Aim: This study aimed to evaluate macular thickness changes following uncomplicated cataract surgery in diabetic patients using OCT and to identify any factors influencing the postoperative recovery process. Me

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Balog, Slaven, Marija Olujić, Antonio Kokot, Štefanija Kolačko, Damir Bosnar, and Jurica Predović. "Does Ultrasound Energy Applied During Phacoemulsification Influence the Thickness of Intraretinal Layers?" Journal of Clinical Medicine 14, no. 9 (2025): 3049. https://doi.org/10.3390/jcm14093049.

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Background: Phacoemulsification (PE) is a gold standard method of cataract surgery. PE causes structural changes in the macula of the eye. The aim was to determine the amount of ultrasound (US) energy applied during PE, the change in thickness of the intraretinal layers, and the correlation between the applied US energy and the change in the thickness of the intraretinal layers in five predefined areas of the macula. Methods: This prospective study included 102 eyes of 79 consecutive subjects without other eye or systemic diseases that can affect the eyes submitted to PE. The macular layer thi

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Krumova, Silviya, Nelly Sivkova, Vassil Marinov, Desislava Koleva-Georgieva, and Desislava Voynikova. "Normal Reference Ranges of Optical Coherence Tomography Parameters in Children." Folia Medica 62, no. 2 (2020): 338–44. http://dx.doi.org/10.3897/folmed.62.e46678.

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Aim: To measure the macular thickness, macular volume and peripapillary retinal nerve fiber layer (RNFL) in healthy Caucasian chil&shy;dren using spectral domain optical coherence tomography (SDOCT) and analyze the correlation of these values with age, refraction, and biometric measurements. Materials and methods: In this cross-sectional study, we recruited 270 healthy children (150 female and 120 male) aged 6 to 17 years with no ocular abnormalities. All children underwent a detailed eye examination. The measurements were obtained using a SDOCT device (SOCT Copernicus REVO). Main outcome

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Zhang, Qinghua, Cong Zhang, Yongxiang Wang, et al. "Quantitative assessments of retinal macular structure among rural-dwelling older adults in China: a population-based, cross-sectional, optical coherence tomography study." BMJ Open 14, no. 2 (2024): e079006. http://dx.doi.org/10.1136/bmjopen-2023-079006.

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ObjectivesTo quantitatively assess and compare retinal macular structures of rural-dwelling older adults in China using two different optical coherence tomography (OCT) scanners and to examine their associations with demographic, lifestyle, clinical and ocular factors.Design, setting and participantsThis population-based, cross-sectional study included 971 participants (age ≥60 years) derived from the Multimodal Interventions to Delay Dementia and Disability in Rural China study. We collected data on demographics, lifestyle factors, clinical conditions (eg, cardiovascular disease (CVD)) and oc

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Academic, Journal of Medical Sciences. "Quantitative Assessment of Macular Thickness in Glaucomatous Human Eye Using Optical Coherence Tomography." Academic Journal of Medical Sciences 10, no. 3 (2024): 74–86. https://doi.org/10.5281/zenodo.12785669.

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<strong>ABSTRACT<em>Background: </em></strong><em>Glaucoma is the cause of thinning of the layer of nerve fibers in the macula. Therefore, an objective study is considered a necessary document to continue evaluating the thickness of the macula. </em><strong><em>Objectives: </em></strong><em>To assess macular thickness by OCT in glaucomatous eyes in comparison to normal eyes and to identify the changes in the macula in glaucoma patients</em><strong><em>Patients and Methods:</em></strong><em> The study included 181 eyes (69 normal eyes and 121 eyes with glaucoma), and each patient underwent a th

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Sobot, Vesna, Vesna Jaksic, Igor Kovacevic, and Dragan Lukic. "The effect of hemodialysis on macular thickness." Srpski arhiv za celokupno lekarstvo, no. 00 (2022): 23. http://dx.doi.org/10.2298/sarh211028023s.

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Introduction/Objective. During hemodialysis (HD) treatment great fluctuations were recorded in the systemic hemodynamic parameters and in the volume and composition of ocular fluid. There are only a few studies that analyzed the effect of HD on retinal and macular thickness with conflicting results. Objective of this study was to determine macular thickness, marked as central foveal thickness, average macular thickness and macular volume, shortly before and after HD. Methods. Prospective study of 30 chronic renal failure (CRF) patients on HD treatment. Thorough ophthalmologic examinations were

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Pua, Tian Siew, and Mohd Izzuddin Hairol. "Evaluating retinal thickness classification in children: A comparison between pediatric and adult optical coherence tomography databases." PLOS ONE 19, no. 12 (2024): e0314395. https://doi.org/10.1371/journal.pone.0314395.

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Purpose This study investigates the agreement of children’s retinal thickness classification by color category between Topcon 3D OCT-1’s built-in adult reference data and our new pediatric database and assesses the correlation of retinal thickness with age and spherical equivalent (SE). Methods 160 eyes of 160 healthy children (74 boys, 86 girls) aged 6–18 years (mean: 11.60 ± 3.28 years) were evaluated in this cross-sectional study. The peripapillary retinal nerve fibre layer (pRNFL) and macular thickness were determined for the 1st, 5th, 95th, and 99th percentile points. Cohen’s κ value and

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Tahir, Tooba Bint, Waqar Muzzaffar, Mahum Faheem, and Ammarah Ashraf. "Macular Thickness Decreases with Age in Normal Eyes: A Study On Macular Thickness Map Protocol on the Oct." Pakistan Armed Forces Medical Journal 72, SUPPL-2 (2022): S212–15. http://dx.doi.org/10.51253/pafmj.v72isuppl-2.7599.

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Objective: To evaluate the normal macular thickness and how it varies with age in the eyes of healthy subjects using macular map protocol on Spectral-Domain Optical Coherence Tomography (SD-OCT). Study Design: Cross-sectional study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi Pakistan, from Jun 2020 to Sep 2021. Methodology: Our study included one thousand seven hundred and four eyes (1704) of healthy subjects. They underwent imaging with macular thickness map protocol using Topcon Spectral-Domain Optical Coherence Tomography (SD-OCT). Acc

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Nurhidayat, Bimanda Rizki, and Dicky Hermawan. "Management of Posterior Capsule Rupture Complication in Cataract Patient with High Myopia and Partial Thickness Macular Hole." Vision Science and Eye Health Journal 1, no. 2 (2022): 49–53. http://dx.doi.org/10.20473/vsehj.v1i2.2022.49-53.

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Introduction: To report clinical outcome after posterior capsule rupture complication in a cataract patient with partial-thickness macular hole. Case presentation: A 49-year-old woman was presented with blurred vision of the left eye two years before admission. The blurred vision increased, accompanied by eye dazzled on light exposure. There was a history of myopia on both eyes and partial-thickness macular hole in the left eye. The left eye visual acuity was 3/60 with S-7.00 correction became 5/12 no improvement with pinhole. There was a partial-thickness macular hole on the left eye in the o

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Li, Fan, Qingli Shang, Guangxian Tang, et al. "Analysis of Peripapillary and Macular Choroidal Thickness in Eyes with Pseudoexfoliative Glaucoma and Fellow Eyes." Journal of Ophthalmology 2020 (June 8, 2020): 1–7. http://dx.doi.org/10.1155/2020/9634543.

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Purpose. To compare differences in peripapillary and macular choroidal thickness in pseudoexfoliative glaucoma (PXG) eyes, nonexfoliative fellow eyes, and normal eyes. Methods. This case-control study included 37 PXG patients (group A: 37 PXG eyes; group B: 37 nonexfoliative fellow eyes) and 37 sex-, age-, and axial length-matched healthy volunteer eyes (group C). Peripapillary and macular choroidal thickness and volume were measured in all subjects via enhanced-depth imaging-optical coherence tomography. Results. The average peripapillary (AP) choroidal thickness was (130.10 ± 46.14) μm, (131

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Galkina, Aleхandra S., Lyudmila A. Katargina, Tatiana B. Kruglova, and Naira S. Egiyan. "Morphometric and functional features in children with pseudophakic myopia after congenital cataract extraction in infancy." Russian Pediatric Ophthalmology 17, no. 4 (2023): 5–15. http://dx.doi.org/10.17816/rpoj110881.

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AIM: To investigate the morphometric parameters of the macular zone in children with pseudophakia and different refractive states after congenital cataract extraction in infancy and their correlations with vision parameters. MATERIAL AND METHODS: Thirty children (49 eyes) who underwent bilateral cataract surgery with primary intraocular lens (IOL) implantation, with a median age at surgery of 7.942.70 (212) months, were identified. These children were divided into two groups: group 1 with target refraction (n=18, 21 eyes) and group 2 with pseudophakic myopia (n=14,28 eyes). All patients

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Kakinoki, Masashi, Taichirou Miyake, Osamu Sawada, Tomoko Sawada, Hajime Kawamura, and Masahito Ohji. "Comparison of Macular Thickness in Diabetic Macular Edema Using Spectral-Domain Optical Coherence Tomography and Time-Domain Optical Coherence Tomography." Journal of Ophthalmology 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/959721.

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Purpose. To compare the macular thicknesses in diabetic macular edema (DME) measured with spectral-domain optical coherence tomography (SD-OCT) and time-domain (TD) OCT.Patients and Methods.The average macular thicknesses of 50 eyes of 29 patients with DME were measured using SD-OCT and TD-OCT.Results.The mean macular thicknesses measured with TD-OCT and SD-OCT were401.5±117.8 μm (mean ± SD) and446.2±123.5 μm, respectively. The macular thicknesses measured with the two devices were well correlated (Pearson's product moment correlation,r=0.977,P<0.001). A significant correlation was found be

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Gungel, H. "Central Macular Thickness in Diabetic Macular Edema." Acta Endocrinologica (Bucharest) 16, no. 4 (2020): 417–25. http://dx.doi.org/10.4183/aeb.2020.417.

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Zolnikova, I. V., S. V. Milash, A. B. Chernyak, et al. "Retinal Postphotoreceptor Layers and Macular Electroretinogram in Retinitis Pigmentosa." Ophthalmology in Russia 17, no. 1 (2020): 81–87. http://dx.doi.org/10.18008/1816-5095-2020-1-81-87.

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Purpose: to assess the inner retinal layer’s changes of the central retina in comparison with bioelectrical activity of macula assessed by MERG and with thickness of photoreceptor retinal layers in patients with retinitis pigmentosa.Patients and methods: 10 patients (20 phakic eyes) with RP were examined. Mean age was 27.0 ± 18.5 years. Mean best corrected visual acuity was 0.38 ± 0.22. The fundus photography electrophysiological studies were performed besides standard ophthalmological examination. Maximal electroretinogram (ERG) or cone-rod response, ERG to 30 Hz flicker and macular ERG were

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NIGAM, Bharti, Pragati GARG, and Priyanka RAJ. "Comparison of Macular and RNFL Thickness in Anisometropic Amblyopia as Compared to Normal Fellow Eyes." Medicina Moderna - Modern Medicine 27, no. 4 (2020): 289–94. http://dx.doi.org/10.31689/rmm.2020.27.4.289.

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Purpose: To compare the macular and peripapillary RNFL thicknesses of the amblyopic and normal eye in patients with anisometropic amblyopia. Methods: This is a hospital based cross-sectional study for which we studied 36 amblyopic subjects aged between 5 to 16 years in which the amblyopic eye was taken as the case and the unaffected eye was taken as control eye. The inclusion criteria included children having unilateral strabismic or anisometropic amblyopia who underwent macular and RNFL thickness assessment by SD-OCT. Results: Central Macular thickness as well as the thickness of the other ma

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