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Journal articles on the topic 'Madhumatī'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2025

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1

Rahman, Md Anichur, AHM Shafiullah Habib, Shova Saha, and Mallika Saha. "Icthyofauna of Madhumati River at Mohammadpur, Magura." Bangladesh Journal of Zoology 49, no. 1 (2021): 19–34. http://dx.doi.org/10.3329/bjz.v49i1.53679.

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The investigation was conducted on the present situation of fish biodiversity and abundance of fish fauna at two different points of Madhumati River at Mohammadpur upazilla under Magura district from October 2018 to September 2019. A total of 83 species of fresh water fish species were recorded belonging to 58 genera of 28 families under 11 orders. Cypriniformes was recorded as the dominant order comprising 26 species constituting 31% of the total. According to IUCN 59% of fish species were Least Concern, 12% were Vulnerable, 11% were Endangered, 9% were Near Threatened, 1% of each were Data D

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2

Reza, Nooreen. "Gothic Melodrama, Hindi Cinema and Subversions of Genre in Madhumati." Film Matters 6, no. 2 (2015): 25–31. http://dx.doi.org/10.1386/fm.6.2.25_1.

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3

Saha, Madhumita. "Left Behind by the Green Revolution." Issues in Science and Technology 39, no. 4 (2023): 90–92. http://dx.doi.org/10.58875/esuj6182.

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4

Rajkhowa, Gaurav. "Book review: Sengupta, Madhumita, Becoming Assamese: Colonialism and New Subjectivities in Northeast India." Social Change 48, no. 2 (2018): 301–3. http://dx.doi.org/10.1177/0049085718768927.

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5

Choudhury, Madhumita, and Angelika Brandt. "Mesosignum weddellensis sp. nov. (Crustacea: Asellota: Mesosignidae), a new isopod species from the abyssal Weddell Sea, Antarctica." Zootaxa 501 (December 31, 2004): 1–10. https://doi.org/10.5281/zenodo.157594.

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Choudhury, Madhumita, Brandt, Angelika (2004): Mesosignum weddellensis sp. nov. (Crustacea: Asellota: Mesosignidae), a new isopod species from the abyssal Weddell Sea, Antarctica. Zootaxa 501: 1-10, DOI: 10.5281/zenodo.157594

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6

Varughese, Emma Dawson. "The Other Side of the Table by Madhumita Mukherjee." World Literature Today 88, no. 1 (2014): 61–62. http://dx.doi.org/10.1353/wlt.2014.0104.

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7

Joshi, Vijay, Madhumita Joshi, Diwas Silwal, Kayce Noonan, Sierra Rodriguez, and Arianne Penalosa. "Systematized biosynthesis and catabolism regulate citrulline accumulation in watermelon." Phytochemistry 162 (June 30, 2019): 129–40. https://doi.org/10.1016/j.phytochem.2019.03.003.

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Joshi, Vijay, Joshi, Madhumita, Silwal, Diwas, Noonan, Kayce, Rodriguez, Sierra, Penalosa, Arianne (2019): Systematized biosynthesis and catabolism regulate citrulline accumulation in watermelon. Phytochemistry 162: 129-140, DOI: 10.1016/j.phytochem.2019.03.003, URL: http://dx.doi.org/10.1016/j.phytochem.2019.03.003

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8

Doti, Brenda Lía, Madhumita Choudhury, and Angelika Brandt. "Holodentata gen. nov. (Isopoda: Asellota: Paramunnidae) with a description of two new species: H. caeca and H. triangulata from the Southern Ocean*." Zootaxa 2096, no. 1 (2009): 395–412. https://doi.org/10.11646/zootaxa.2096.1.24.

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Doti, Brenda Lía, Choudhury, Madhumita, Brandt, Angelika (2009): Holodentata gen. nov. (Isopoda: Asellota: Paramunnidae) with a description of two new species: H. caeca and H. triangulata from the Southern Ocean*. Zootaxa 2096 (1): 395-412, DOI: 10.11646/zootaxa.2096.1.24, URL: https://biotaxa.org/Zootaxa/article/view/zootaxa.2096.1.24

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9

Chhetri, Purna Bahadur, and Damodar Thapa Chhetry. "Physico-chemical parameters and primary productivity of a fish pond of Madhumara, Biratnagar." Nepalese Journal of Biosciences 3, no. 1 (2013): 38–44. http://dx.doi.org/10.3126/njbs.v3i1.41441.

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The physico-chemical parameters and primary productivity of a fish pond of Madhumara, Biratnagar was studied from October 2007 to September 2008. The maximum air and water temperature and water transparency were recorded in rainy season, whereas maximum pH, dissolved oxygen and chloride were recorded in winter season. Free carbon dioxide and total hardness were maximum in summer season. The gross primary productivity, net primary productivity and community respiration were found maximum in winter season.

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10

Menon, Unnikrishnan K., Janhvi J. Bhate, and K. Madhumita. "A Stitch in Time." International Journal of Phonosurgery & Laryngology 3, no. 1 (2013): 31–33. http://dx.doi.org/10.5005/jp-journals-10023-1057.

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ABSTRACT Bilateral vocal cord paralysis is the one of the common childhood laryngeal lesions. The treatment modalities include interim tracheostomy and, where needed, permanent irreversible procedures. We report a case of idiopathic bilateral vocal cord palsy in a child, which was managed effectively by the procedure of suture lateralization of the vocal cord. The procedure, its rarity and follow-up of our case is described. How to cite this article Bhate JJ, Menon UK, Madhumita K. A Stitch in Time. Int J Phonosurg Laryngol 2013;3(1):31-33.

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11

Deepthi, NV, Janhvi J. Bhate, and K. Madhumita. "Rare Benign Tracheal Lesions." International Journal of Phonosurgery & Laryngology 2, no. 1 (2012): 37–40. http://dx.doi.org/10.5005/jp-journals-10023-1033.

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ABSTRACT Breathing difficulty, change in voice and hemoptysis are symptoms that are seen with varying degrees of frequency in the routine ENT OPD. The focus of examination and investigation is usually the larynx in such cases. It is rare for the diagnosis to be a tracheal lesion. We report three cases of uncommon benign tracheal lesions. Our aim is to highlight the presentation of such cases in a tertiary care center, and the relevant modalities of management. How to cite this article Bhate JJ, Deepthi NV, Menon UK, Madhumita K. Rare Benign Tracheal Lesions. Int J Phonosurg Laryngol 2012;2(1):

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12

Kailash Sahu. "Study of antioxidant and anti-diarrheal activity of whole plant of Madhumalti {Quisqualis indica Linn.}." GSC Biological and Pharmaceutical Sciences 29, no. 2 (2024): 096–103. http://dx.doi.org/10.30574/gscbps.2024.29.2.0417.

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Hole plant of Quisqualis indica Linn. (Family Combretaceae) is commonly known as Rangoon creeper (combretum indicum) or madhumalati, traditionally used as anthelmintic The fresh plantwas studied for pharmaconostic evaluations, including examination of morphological and microscopic characters, determination of plantconstants, ash values and extractive values. The morphological studies revealed that the leaf is in dark green color with characteristic odour and slight bitter taste and. The shape of Quisqualis indica leaves is as ellipticalacuminate with entire margin, cordate base, and length var

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Kailash, Sahu. "Study of antioxidant and anti-diarrheal activity of whole plant of Madhumalti {Quisqualis indica Linn.}." GSC Biological and Pharmaceutical Sciences 29, no. 2 (2024): 096–103. https://doi.org/10.5281/zenodo.14753338.

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Hole plant of <em>Quisqualis indica</em> Linn. (Family Combretaceae) is commonly known as Rangoon creeper (combretum indicum) or madhumalati<em>, </em>traditionally used as anthelmintic The fresh plantwas studied for pharmaconostic evaluations<em>, </em>including examination of morphological and microscopic characters<em>, </em>determination of plantconstants<em>, </em>ash values and extractive values. The morphological studies revealed that the leaf is in dark green color with characteristic odour and slight bitter taste and. The shape of <em>Quisqualis indi

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14

Rani, M. H., M. Faruquee, M. S. R. Khanom, and S. N. Begum. "Genetic variability and multivariate studies on the grain physical properties of rice (Oryza sativa L.) landraces." SABRAO Journal of Breeding and Genetics 54, no. 1 (2022): 1–10. http://dx.doi.org/10.54910/sabrao2022.54.1.1.

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Thirty rice landraces were evaluated during the 2020 wet season for the estimation of the genetic variability of six grain physical properties, viz. grain length (GL), grain breadth (GB), milled grain length (MGL), milled grain breadth (MGB), milled grain length breadth ratio (MGL/MGB), and 1000-grain weight (TGW), at the Bangladesh Institute of Nuclear Agriculture Substation, Sunamganj, Bangladesh. The relative contribution of these traits to variability was estimated by using principal component analysis (PCA), and the landraces were clustered by using Mahalanobis distance (D2) statistics. T

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15

Dasgupta, Rajib. "Health Promotion and Education: Foundations for Changing Health Behavior." Journal of Comprehensive Health 10, no. 1 (2022): 45–46. http://dx.doi.org/10.53553/jch.v10i01.010.

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The ongoing COVID-19 pandemic has reemphasized the criticality of human behaviors and led to an enormous focus on health promotion and risk communication messaging; ‘COVID appropriate behavior’ is indeed a household term now. Dedicated or specialist health promotion professionals and scholars are few and far between and the author, Professor Madhumita Dobe, is both a pioneer and icon to generations of public health students and researchers. She has authored this book, filling up a much-needed void in this discipline. As she has acknowledged, this book is the culmination of a lifetime of teachi

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16

Sable, Neha A., and Nisha Shinde. "Prevalence of Wrist Pain in Young Tabla Players: Observational Study." International Journal of Health Sciences and Research 12, no. 5 (2022): 10–14. http://dx.doi.org/10.52403/ijhsr.20220502.

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Background: The most popularly used percussion instruments in Indian classical music is Tabla. Playing a percussion instrument demands great force & effort, which may make percussionists prone to playing-related musculo skeletal disorders (PRMDs). Method: A Prevalence study using convenience sampling technique was done from the music schools of Pune-Godse & Madhumati Sangeet Vidyalay with 104 subjects. The subjects aged between 11 to 25 yr old Both males & females who plays table atleast from1 yr. Wrist pain was assessed by using Numeric pain rating scale (NPRS) Subjects rated the

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17

Bango, Madhumita. "Explaining the social gradient in health: inequality in health outcomes in selected states of India, 2015‑2016." Journal of Health Inequalities 8, no. 2 (2022): 155–62. http://dx.doi.org/10.5114/jhi.2022.122112.

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18

Meraj, Gowhar, Tanzeel Khan, Shakil A. Romshoo, Majid Farooq, Kumar Rohitashw, and Bashir Ahmad Sheikh. "An Integrated Geoinformatics and Hydrological Modelling-Based Approach for Effective Flood Management in the Jhelum Basin, NW Himalaya." Proceedings 7, no. 1 (2018): 8. http://dx.doi.org/10.3390/ecws-3-05804.

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In the present study, using static land system parameters, such as geomorphology, land cover, and relief, we calculated the water yield potential (RP) of all the watersheds of the Jhelum basin (Kashmir Valley) using the analytical hierarchy process (AHP) based watershed evaluation model (AHP-WEM). The results revealed that among the 24 watersheds of the Jhelum basin, the Vishav watershed, with the highest RP, is the fastest water yielding catchment of the Jhelum basin followed by Bringi, Lidder, Kuthar, Sind, Madhumati, Rembiara, Sukhnag, Dal, Wular-II, Romshi, Sandran, Ferozpur, Viji-Dhakil,

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19

Madhumita, Madhumita, Jon Teague, Philip A. Beer, and Zbyslaw Sondka. "Abstract 7507: Towards transparent and context-specific annotation of driver and passenger mutations in cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 7507. https://doi.org/10.1158/1538-7445.am2025-7507.

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Abstract Cancer arises from the accumulation of somatic genetic alterations, with only a subset acting as "drivers" that promote malignant transformation. Distinguishing between driver and passenger mutations is fundamental for both clinical and research applications, yet current in-silico variant annotation tools often fall short. Our previous evaluation of multiple algorithms revealed a concerning reliance on pre-computed, black-box models that are rarely updated and typically limited to missense mutations. These tools also lack transparency and biological context, leading to inconsistent pr

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20

Vassiley, Alexis. "Jörg Nowak, Madhumita Dutta and Peter Birke (eds), Workers’ Movements and Strikes in the Twenty-First Century: A Global Perspective." Journal of Industrial Relations 62, no. 3 (2020): 508–10. http://dx.doi.org/10.1177/0022185620924134.

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21

Dekhane, Swapnil, Narendra Kumar, and R. R. Pisal. "Integrated Nutrient Management in Muskmelon: A Comprehensive Field Study." Journal of Experimental Agriculture International 46, no. 6 (2024): 284–90. http://dx.doi.org/10.9734/jeai/2024/v46i62478.

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The present study aims to describe the effects of integrated nutrient management (INM) on Madhumita variety of muskmelon cultivation in terms of plant growth, fruit yield, and quality. The experiment has been carried out in the crop field located in the North Konkan region of Maharashtra, India. This case study involved seven different treatments (T1 to T7), each with varying nutrient application regimes. Certain observational data, such as vine length, number of leaves per plant, leaf length, days to 50% flowering, number of fruits per plant, fruit length, fruit width, fruit weight, and fruit

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22

Thete A. M., Dahat D. V., Jambhale V. M., and Chaudhari S. R. "Molecular Characterization of Rice Genotypes Using Molecular Markers." International Journal of Plant & Soil Science 35, no. 20 (2023): 284–301. http://dx.doi.org/10.9734/ijpss/2023/v35i203809.

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Rice, (Oryza sativa L. 2n=24) belongs to the family Gramineae and subfamily Oryzoideae. Oryza has two cultivated species: Oryza sativa and Oryza glaberrima. Breeding for good-quality traits requires the selection of parents with a wider genetic diversity. Molecular markers are used in molecular biology and biotechnology to identify a sequence of DNA. Molecular markers have played an increasing role in rice breeding for cultivar improvement, screening, selection, and germplasm collections. The present investigation is undertaken to study the genetic diversity among thirty rice genotypes using t

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23

Fishwick, Adam. "Book Review: Workers’ Movements and Strikes in the Twenty-First Century: A Global Perspective by Jörg Nowak, Madhumita Dutta and Peter Birke (eds)." Capital & Class 44, no. 1 (2020): 115–17. http://dx.doi.org/10.1177/0309816820910010c.

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24

Vaidik, Aparna. "Clare Anderson, Madhumita Mazumdar, and Vishvajit Pandya. New Histories of the Andaman Islands: Landscape, Place and Identity in the Bay of Bengal, 1790–2012." American Historical Review 123, no. 4 (2018): 1300–1301. http://dx.doi.org/10.1093/ahr/rhy197.

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25

Sondka, Zbyslaw, Madiha Ahmed, Joanna Argasinska, et al. "Abstract 3555: COSMIC: two decades of curating somatic variants in cancer." Cancer Research 84, no. 6_Supplement (2024): 3555. http://dx.doi.org/10.1158/1538-7445.am2024-3555.

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Abstract In 2004, COSMIC was one of the first initiatives to integrate global data on somatic mutations in cancer. At the time it was explicit that the fragmentation of genetic datasets was a major obstacle to understand the processes driving cancer. A team of expert curators and bioinformaticians was tasked with identifying and cataloguing data related to somatic variants, as well as relevant demographic, clinical, and patient information from published studies and making these data easily accessible to the research community. Over the last two decades we have witnessed the incredible progres

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Deol, Jeevan Singh. "Mīr Sayyid Manjhan Shattārī. Madhumālatī: an Indian Sufi Romance. Trans. Aditya Behl and Simon Weightman with Shyam Manohar Pandey. pp. 336. Oxford, Oxford University Press, 2000." Journal of the Royal Asiatic Society of Great Britain & Ireland 13, no. 1 (2003): 122–23. http://dx.doi.org/10.1017/s1356186303293044.

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Nazli, Samina. "Madhumita Puri and George Abraham (eds.). Handbook of Inclusive Education for Educators, Administrators, and Planners: Within Walls, Without Boundaries. New Delhi: Sage Publications, 2004. 309 pages. Paperback. Indian Rs 450.00." Pakistan Development Review 42, no. 3 (2003): 280–81. http://dx.doi.org/10.30541/v42i3pp.280-281.

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The book is a manual aimed at educators, administrators, and planners involved in dealing with disabled children. Although education is considered to be a basic human right, yet according to UNICEF some 113 million children have no access to education. For disabled children, “only 1 in every 50 children with disability has access to education” (p. 18). The manual has been organised in three parts. Part I is basically a bird’s eye view of Inclusive Education. The term is defined on page 25 of the book in the following words: “Inclusive education is concerned with removing all barriers to learni

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Das, Madhumita, Kymkecia Henry, Djarie Armstrong, et al. "Abstract 7077: Immunofluorescence microtissue array (IMA) for detection of prognostic cancer stem cell biomarkers." Cancer Research 85, no. 8_Supplement_1 (2025): 7077. https://doi.org/10.1158/1538-7445.am2025-7077.

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Abstract Cancer is an intricate disease accountable for the deaths of over 10 million people per year in the United States of America. Several scientific studies showed that the cancer stem cell (CSC) markers have prognostic significance in various cancers and are crucial for designing anticancer drugs to lower cancer death. However, there was a lack of rapid, accurate identification, and analysis, of the prognostic cancer stem cell (CSC) biomarkers in numerous cancer patients. In our laboratory, we identified and analyzed prognostic lung cancer stem cell markers (LCSCs) by using the Immunoflu

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Madhumita, Zbyslaw Sondka, and Jon Teague. "Abstract 4884: Evaluating the utility of in silico variant annotation tools for cancer driver detection." Cancer Research 84, no. 6_Supplement (2024): 4884. http://dx.doi.org/10.1158/1538-7445.am2024-4884.

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Abstract In cancer genomics, precise variant annotation is crucial for clinical decisions, drug development, and research. The burgeoning genomic data offers an opportunity to use data-driven approaches to generate knowledge that supports clinical decisions. Particularly machine learning (ML) and Deep learning (DL), are becoming essential, as their application is fast, scalable, simple to implement, and generates reproducible results. The methods ranging from simple sequence-based alignment scoring to advanced algorithms like Logistic regression, Support vector machine, and Recurrent neural ne

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Ghazi, Phaedra, Kayla O'Toole, Sanjana Boggaram, et al. "Abstract 4322: Inhibition of ULK and KRASG12C control tumor growth in preclinical models of lung cancer." Cancer Research 84, no. 6_Supplement (2024): 4322. http://dx.doi.org/10.1158/1538-7445.am2024-4322.

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Abstract Approximately 30% of lung cancers are driven by mutationally activated KRAS. The recent FDA approval of sotorasib, a direct pharmacological inhibitor of KRASG12C, marks a critical milestone in the treatment of this important subset of lung cancer. However, a major obstacle in treating lung cancer is resistance to current therapeutic treatments. In response to cellular stresses such as RAS pathway-targeted therapeutics, RAS-mutated cancer cells have been demonstrated to increase autophagy, an intracellular recycling pathway. However, the mechanism(s) underlying treatment-induced autoph

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Anderson, Juan, Mariah Delgado, Malcolm Lovett, et al. "Abstract 859: Development of non-smoking lung cancers by indoor carcinogenic aerosols through epigenetic reprogramming of lung stem cells: Bioinformatics and artificial intelligence analysis." Cancer Research 84, no. 6_Supplement (2024): 859. http://dx.doi.org/10.1158/1538-7445.am2024-859.

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Abstract Several scientific studies discovered the toxic effects of indoor aerosols on different organs’ adult stem cells of the human body. The most importantly, the indoor toxic aerosols comprised of numerous carcinogens namely, sodium dodecyl sulfate, phthalic acids from floor cleaners, formaldehyde, acetaldehyde, benzene, toluene, ethyl benzene, xylenes, from air fresheners, Hydramethylnon, Pyrethrins, imiprothrin, cypermethrin, tetramethrin, prallethrin and permethrin from ant and roach Killer. However, there was a lack of analysis revealing the mechanism of toxic effects and epigenetic r

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McMahon, Martin, Madhumita Bogdan, Mary J. Timson, et al. "Abstract 3600: DCC-3116, a first-in-class selective inhibitor of ULK1/2 kinases and autophagy, synergizes with the KRASG12C inhibitor sotorasib resulting in tumor regression in KRAS mutant NSCLC xenograft models." Cancer Research 82, no. 12_Supplement (2022): 3600. http://dx.doi.org/10.1158/1538-7445.am2022-3600.

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Abstract Mutationally-activated RAS oncoproteins are detected in approximately 19% of newly diagnosed human cancers and have been targets for drug discovery for over 40 years. Recently, the FDA approved sotorasib, a covalent inhibitor of KRASG12C, for the treatment of non-small cell lung cancer (NSCLC). Although sotorasib demonstrated clear clinical benefits, the emergence of drug resistance has led to drug combination approaches with the goal of deepening and sustaining the durability of patient responses. One potential mechanism of drug resistance is the induction of autophagy, which cancer

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Zack, Travis Ian, Madhumita Sushil, Brenda Miao, et al. "Abstract B074: Clinical inference of location and trajectory of pancreatic cancer from radiology reports using zero-shot LLM." Cancer Research 84, no. 2_Supplement (2024): B074. http://dx.doi.org/10.1158/1538-7445.panca2023-b074.

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Abstract Importance: Recent breakthroughs in Large Language models (LLM) have shown impressive reasoning capabilities. Inferring disease trajectory from radiology reports is a central task in clinical oncology, and radiographic interpretation of disease state and treatment benefits in pancreas cancer can be particularly challenging. We assess the performance of LLMs (GPT3.5-turbo and GPT4) to infer disease status, response to treatment, and location of disease for patients with pancreatic adenocarcinoma from clinical radiology reports. We also assess the ability of LLMs to extrapolate from obj

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Solomon, Benedrica, Richgena Sturrup, Jada Dixon, et al. "Abstract 5830: Carcinogenic effects of metal and metalloids through epigenetic reprogramming of human bone marrow stem cells: The bioinformatics database analysis." Cancer Research 82, no. 12_Supplement (2022): 5830. http://dx.doi.org/10.1158/1538-7445.am2022-5830.

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Abstract Many scientific studies showed that the carcinogenic effects of environmental contamination of several metal and metalloids on bone marrow stem cells of human body. These carcinogens include, Cadmium, Mercury, Chromium, Aluminum, Nickel and Arsenic. However, there was no such analysis for elucidating the mechanism of carcinogenic effects and epigenetic reprogramming of human bone marrow stem cells. In this study, we analyzed the carcinogenic effects of mentioned carcinogens, and the mechanism of epigenetic reprogramming using NIH Toxicology Data Network (TOXNET), Comparative Toxico-ge

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Shepard, Akilah, Oneilia Yearde, Juan Sanchez, et al. "Abstract 6584: Potential carcinogenic effects of electronic nicotine delivery systems through epigenetic reprogramming in oral, brain, and lung stem cells." Cancer Research 83, no. 7_Supplement (2023): 6584. http://dx.doi.org/10.1158/1538-7445.am2023-6584.

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Abstract Recent scientific studies exhibited that the electronic nicotine delivery systems (ENDS) aerosols comprise numerous carcinogens namely propylene glycol, diacetyl, formaldehyde, acetaldehyde, crotonaldehyde (2-butenal), acetone, acetyl propionyl (2,3-pentanedione), acrolein, nicotine, arsenic, cadmium and radioisotopes, such as Polonium-210 and lead-210. However, there was no such investigation for clarifying the mechanism of carcinogenic effects and epigenetic reprogramming of human oral, brain, and lung stem cells. In this study, we investigated the carcinogenic effects of ENDS aeros

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Bogdan, Madhumita, Mary J. Timson, Hikmat Al-Hashimi, Bryan D. Smith, and Daniel L. Flynn. "Abstract 4872: DCC-3116, a first-in-class selective ULK1/2 inhibitor of autophagy, in combination with the KIT inhibitor ripretinib induces complete regressions in GIST preclinical models." Cancer Research 83, no. 7_Supplement (2023): 4872. http://dx.doi.org/10.1158/1538-7445.am2023-4872.

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Abstract Background: Cancer cells activate autophagy as an adaptive stress response (ASR) mechanism to therapies targeting the RTK/RAS/MAPK/PI3K pathways, limiting antitumor response. Autophagy is initiated through ULK1/2 kinases and is triggered by inhibitors of the MAPK and PI3K pathways. Most gastrointestinal stromal tumors (GIST) are driven by mutations in KIT kinase. KIT signals through MAPK/PI3K pathways, suppressing ULK1/2 kinases and autophagy1,2,3. Inhibition of mutant KIT reverses this suppression, activating autophagy and cancer cell survival. Approved therapies for GIST include ima

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Ghazi, Phaedra C., Conan Kinsey, Madhumita Bogdan, Bryan D. Smith, Daniel L. Flynn, and Martin McMahon. "Abstract PR03: Cooperative anti-tumor effects of combined inhibition of KRASG12C plus autophagy in preclinical models of KRASG12C-driven lung cancer." Molecular Cancer Research 21, no. 5_Supplement (2023): PR03. http://dx.doi.org/10.1158/1557-3125.ras23-pr03.

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Abstract Approximately 25% of lung cancers are driven by mutationally-activated KRAS. A major obstacle in treating lung cancer is resistance to current therapeutic treatments. The recent FDA approval of sotorasib, a direct pharmacological inhibitor of KRASG12C, marks a critical milestone in the treatment of this important subset of lung cancer. However, the twin problems of primary or acquired resistance to direct pharmacological inhibition of KRASG12C remain major obstacles in sustaining the deepest and most durable patient responses. In response to cellular stresses such as RAS pathway-targe

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Nair, Madhumathy G., Chandrakala M, Apoorva D, et al. "Abstract P3-10-06: High levels of miR-18a is associated with increased proliferation but suppression of EMT phenotype in ER negative breast cancer." Cancer Research 82, no. 4_Supplement (2022): P3–10–06—P3–10–06. http://dx.doi.org/10.1158/1538-7445.sabcs21-p3-10-06.

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Abstract Introduction: miRNA-based regulation has been implicated in tumor evolution and progression. miR-18a belonging to the miR-17-92 polycistronic cluster has also been reported to have oncogenic effects across multiple cancer types including breast cancer. We have previously demonstrated the epigenetic regulation of ER by miR-18a and its high levels as a poor prognostic marker in ER-positive breast tumors (Nair et al, Cancer Med. 2016). Here, we have examined the effects of high expression of miR-18a in the ER-negative subtype of breast cancer. Methods: 275 surgically excised specimens of

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Bogdan, Madhumita, Mary J. Timson, Hikmat Al-Hashimi, Bryan D. Smith, and Daniel L. Flynn. "Abstract 1377: DCC-3116, a first-in-class selective inhibitor of ULK1/2 kinases and autophagy, synergizes with encorafenib and cetuximab in BRAF V600E mutant colorectal cancer models." Cancer Research 83, no. 7_Supplement (2023): 1377. http://dx.doi.org/10.1158/1538-7445.am2023-1377.

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Abstract Background: Cancer cells activate autophagy through ULK1/2 kinases as an adaptive stress response (ASR) mechanism to therapies targeting the RTK/RAS/MAPK/PI3K pathways, limiting antitumor response. BRAF signals through the MAPK pathway while EGFR signals upstream through both the MAPK and PI3K pathways, suppressing ULK1/2 kinases and autophagy. Inhibition of mutant BRAF and EGFR reverses this suppression, activating the autophagy ASR1-4. The BRAF V600E mutation occurs in ~10% of colorectal cancer (CRC) patients. Approved treatments for these patients include the BRAF V600E inhibitor e

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Bogdan, Madhumita, Jodi Simeon, Mary J. Timson, Hikmat Al-Hashimi, Bryan D. Smith, and Daniel L. Flynn. "Abstract C074: VPS34 inhibition delays activation-induced STING degradation to prolong STING signaling and improve anti-tumor efficacy in preclinical models." Molecular Cancer Therapeutics 22, no. 12_Supplement (2023): C074. http://dx.doi.org/10.1158/1535-7163.targ-23-c074.

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Abstract Background: The STING/interferon (IFN) response pathway has been a target of cancer immunotherapy for many years, as a method for reactivating the anti-tumor immune response. Stimulation of the STING pathway leads to activation and infiltration of immune cells into the tumor, and cancer cell death. However, multiple STING agonists have failed in the clinic due to poor efficacy or toxicity1. STING activation leads to its degradation within a few hours through trafficking to the lysosome, as a mechanism to control immune cell hyperactivation2. Although this safety mechanism is important

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Rajarajan, Savitha, Snijesh VP, Madhumathy G. Nair, et al. "Abstract P2-19-02: Androgen mediated signaling induces epithelial to mesenchymal transition phenotype in MDA-MB-453 breast cancer cells and human breast tumors." Cancer Research 83, no. 5_Supplement (2023): P2–19–02—P2–19–02. http://dx.doi.org/10.1158/1538-7445.sabcs22-p2-19-02.

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Abstract Background: Epithelial-mesenchymal transition (EMT) phenotype is a complex process and plays a central role in tumor progression, aggression, invasion, metastasis, and resistance to therapy. Role of androgen receptor (AR) and androgens in inducing EMT has been well established in experimental systems of prostate cancer. AR is widely expressed in all subtypes of breast cancer (BC) and is considered to have context dependent role based on the steroid hormone microenvironment. Previous studies have shown AR as the only sex steroid receptor detectable in BC metastases and in metastatic le

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Indrani, Trivedi, Prasad Trivedi Maheshwar, Kishore Sinha Upendra, Anupama, and Kumar Ambasta Sanjeev. "Effect of Various Growth Hormone Concentration and Combination on Protocol Optimization for In vitro Rapid Propagation of Withania somnifera." Biolife 3, no. 4 (2022): 889–96. https://doi.org/10.5281/zenodo.7306856.

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<strong>ABSTRACT</strong> <em>Withania somnifera(l.) </em>Dunal is commonly known as ashwagandha and belongs to family Solanaceae. The plant is an erect undershrub with long tuberous roots. All the parts of the plants have shown remarkable significance in the field of pharmacology. The major chemical constituents of this plant is withanolide A and D. These are anti-inflammatory and enhance the bodies defence against infections and tumours. Generally leaves and roots are used as drug. Multiple uses of the plant have made it an endangered species. In view of these facts, the study was conducted

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Bali, Bikram Singh, Ahsan Afzal wani, Rais Ahmad Khan, and Shabir Ahmad. "Morphotectonic analysis of the Madhumati watershed, northeast Kashmir Valley." Arabian Journal of Geosciences 9, no. 5 (2016). http://dx.doi.org/10.1007/s12517-016-2395-9.

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Bhuiyan, M. R., M. Ahsan, A. Aziz, and S. Begum. "SALINE WATER INGRESSION IN UPPER PART OF BALESWAR RIVER NEAR NAZIRPUR UNDER PIROJPUR DISTRICT: A CASE STUDY." Khulna University Studies, November 8, 2022, 301–8. http://dx.doi.org/10.53808/kus.2000.2.2.0056-l.

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A five year project was undertaken to address the salinity problem in the upstream of Baleswar river. The information generated during this period have been presented in this paper. Previously the Madhumati-Baleswar river system was completely non saline throughout the year. Recently upstream fresh water flow from the Madhumati river through the Baleswar river passing in between Chitalmari and Nazirpur Upazila is about to cease due to prolonged siltation on the river bed. During intensive monitoring work (1995-1999) some canals such as the Chitra river, Vasa canal, Santoshpur canal, Lara canal

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Mostafa, Muhtasim Shahriar, Md Jahir Uddin, Md Nazmul Haque, and Muhammad Tauhidur Rahman. "Unraveling Meandering River Morphodynamics: A Geospatial Investigation of the Madhumati River in Bangladesh." Physics and Chemistry of the Earth, Parts A/B/C, October 2024, 103788. http://dx.doi.org/10.1016/j.pce.2024.103788.

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Biswas, Rathindra Nath, Md Nazrul Islam, M. Nazrul Islam, and Sanjib Sarker Shawon. "Modeling on approximation of fluvial landform change impact on morphodynamics at Madhumati River Basin in Bangladesh." Modeling Earth Systems and Environment, October 20, 2020. http://dx.doi.org/10.1007/s40808-020-00989-2.

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Pandey, Somjeeta, and Somdatta Bhattacharya. "The Mysteries of Food: Reading Select Detective Fiction by Kalpana Swaminathan and Madhumita Bhattacharyya." Rupkatha Journal on Interdisciplinary Studies in Humanities 12, no. 5 (2020). http://dx.doi.org/10.21659/rupkatha.v12n5.rioc1s15n3.

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Food studies, a new addition to the family of humanities, has experienced a rapid rise in the last twenty years and a number of scholars have devoted their time and energy in studying food culture as well as the patterns of eating (Albala, 2013). Food writing has slowly spread its branches into all literary genres including into crime fiction. In more recent crime mysteries, the main plot is supplemented by authentic recipes and descriptions of food and cooking and “gumshoes not only track killers” but also “grill sherry-flavoured tuna” or “bake” chocolate cookies (Carvajal, 1997). The sub-gen

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Gazi, Md Yousuf, Farhad Hossain, Sumiya Sadeak, and Md Mahin Uddin. "Spatiotemporal variability of channel and bar morphodynamics in the Gorai-Madhumati River, Bangladesh using remote sensing and GIS techniques." Frontiers of Earth Science, November 2, 2020. http://dx.doi.org/10.1007/s11707-020-0827-z.

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Aziz, Zaib un Nisa. "Riotous Lives and Subversive Literatures: New Directions in Global Histories of Resistance." Itinerario, February 5, 2024, 1–12. http://dx.doi.org/10.1017/s0165115323000323.

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Abstract Over the past two decades, the relatively young field of global history has generated remarkable excitement among students, scholars, and readers who want to read scholarship that crosses borders and brings many worlds to a single methodological framework. Global perspectives have been particularly fruitful for telling political histories that have defined the modern world. Today, there is increasing scholarly interest in writing global intellectual histories of decolonisation and anti-colonialism. In the pages that follow, I consider new work, situated in several disciplines, that pu

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Gull, Sarvat, Shagoofta Rasool Shah, and Ayaz Mohmood Dar. "Assessing land use/land cover change detection of north-eastern watersheds of Kashmir valley using GIS and remote sensing techniques." Water Practice and Technology, July 20, 2022. http://dx.doi.org/10.2166/wpt.2022.085.

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Abstract Land use changes in the Kashmir Himalayas must be mapped and monitored for long-term development and efficient planning. This work uses geospatial technologies like Remote Sensing and Geographic Information System to track changes in Land cover trends in four main watersheds in the Kashmir Valley's north-eastern Himalayas from 2003 to 2013. Land cover maps were created using images from the Landsat-5 Thematic Mapper. The watershed's Land use/Land cover maps were created using supervised classification utilizing the Maximum Likelihood Classifier (MLC). Over the previous decade, the lan

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