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Journal articles on the topic 'MADSAM'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Kwak, Soyoung, Mathieu Boudier-Revéret, Hee Kyung Cho, and Min Cheol Chang. "Multifocal acquired demyelinating sensory and motor neuropathy misdiagnosed as carpal tunnel syndrome: a case report." Journal of International Medical Research 49, no. 3 (2021): 030006052199889. http://dx.doi.org/10.1177/0300060521998896.

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Multifocal acquired demyelinating sensory and motor neuropathy (MADSAM), a subtype of chronic inflammatory demyelinating polyneuropathy, is a non-compressive peripheral nerve disorder. Symptoms of MADSAM include asymmetrical weakness and sensory deficits in the distribution of individual peripheral nerves, which are frequently noted in the distal portion of peripheral nerves. MADSAM can be easily misdiagnosed as any of the various compressive peripheral neuropathies. Here, we present a case of MADSAM misdiagnosed as carpal tunnel syndrome (CTS). A 53-year-old woman had bilateral asymmetrical h

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Tumilovich, Taisiya A., Victoria V. Sinkova, Daria A. Grishina, et al. "Neuroimaging Markers for Differential Diagnosis Between Multifocal Motor Neuropathy and Multifocal Acquired Demyelinating Sensory and Motor Neuropathy." Annals of Clinical and Experimental Neurology 18, no. 1 (2024): 20–32. http://dx.doi.org/10.54101/acen.2024.1.3.

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Introduction. Similar asymmetric patterns of motor disorders and neurophysiological changes complicate the differential diagnosis between multifocal motor neuropathy (MMN) and multifocal acquired demyelinating sensory and motor neuropathy (MADSAM) as two chronic dysimmune neuropathies with significantly different treatment approaches. The lack of specific paraclinical markers often result in misdiagnosis and selection of ineffective specific therapy. Identification of specific neuroimaging biomarkers to differentiate these conditions may improve diagnostic approaches. Objective: To ident

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Shimizu, Fumitaka, Mariko Oishi, Setsu Sawai, et al. "Increased IP-10 production by blood–nerve barrier in multifocal acquired demyelinating sensory and motor neuropathy and multifocal motor neuropathy." Journal of Neurology, Neurosurgery & Psychiatry 90, no. 4 (2018): 444–50. http://dx.doi.org/10.1136/jnnp-2018-319270.

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ObjectiveDysfunction of the blood–nerve barrier (BNB) plays important roles in chronic inflammatory demyelinating polyneuropathy (CIDP) and multifocal motor neuropathy (MMN). The aim of the present study was to identify the candidate cytokines/chemokines that cause the breakdown of the BNB using sera from patients with CIDP and MMN.MethodsWe determined the levels of 27 cytokines and chemokines in human peripheral nerve microvascular endothelial cells (PnMECs) after exposure to sera obtained from patients with CIDP variants (typical CIDP and multifocal acquired demyelinating sensory and motor n

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Ikeda, Shohei, Haruki Koike, Ryoji Nishi, et al. "Clinicopathological characteristics of subtypes of chronic inflammatory demyelinating polyradiculoneuropathy." Journal of Neurology, Neurosurgery & Psychiatry 90, no. 9 (2019): 988–96. http://dx.doi.org/10.1136/jnnp-2019-320741.

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ObjectiveTo evaluate the clinical and pathological correlations characterising each clinical subtype of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).MethodsWe assessed 106 consecutive patients who had CIDP fulfilling the European Federation of Neurological Societies and Peripheral Nerve Society criteria and had been referred for sural nerve biopsy. Patients with anti-neurofascin 155, anti-contactin 1 and anti-LM1 antibodies were excluded.Results55 patients were classified as having typical CIDP. Regarding atypical CIDP, the multifocal acquired demyelinating sensory and moto

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Erdener, Şefik Evren, Çağrı Mesut Temuçin, Figen Söylemezoğlu, Rahşan Göçmen, and Aslı Tuncer Kurne. "Tumefactive Brain Demyelination Accompanying MADSAM Neuropathy." Türk Nöroloi Dergisi 21, no. 3 (2015): 98–101. http://dx.doi.org/10.4274/tnd.68736.

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6

Trikamji, Bhavesh, Edward Chang, and Shri K. Mishra. "West Nile Virus and MADSAM Neuropathy." Journal of Clinical Neuromuscular Disease 16, no. 4 (2015): 223–24. http://dx.doi.org/10.1097/cnd.0000000000000067.

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7

Ng, K. "MADSAM neuropathy: An unusual cause of pseudoathetosis." Neurology 83, no. 3 (2014): 291. http://dx.doi.org/10.1212/wnl.0000000000000595.

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8

Katz, Jonathan S., and David S. Saperstein. "Asymmetric acquired demyelinating polyneuropathies: MMN and MADSAM." Current Treatment Options in Neurology 3, no. 2 (2001): 119–25. http://dx.doi.org/10.1007/s11940-001-0046-1.

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9

Schminke, Ulf, and Christine Holbe. "Sonografie peripherer Nerven: Immun-Neuropathien." Klinische Neurophysiologie 50, no. 02 (2019): 89–95. http://dx.doi.org/10.1055/a-0891-4433.

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ZusammenfassungImmun-Neuropathien sind seltene Erkrankungen, die allerdings frühzeitig einer kausalen Therapie zugeführt werden sollten, sodass es von großer Wichtigkeit ist, möglichst zuverlässig diese Immun-Neuropathie zu diagnostizieren. Der folgende Artikel hat zum Ziel, eine Übersicht über die typischen sonografischen Befunde sowie über den Zusatznutzen der Sonografie gegenüber der elektrophysiologischen Untersuchung bei Immun-Neuropathien wie der chronischen inflammatorischen demyelinisierenden Polyneuropathie (CIDP), systemischen Vaskulitiden, der multifokalen akquirieten demyelinisiere

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10

Özkara, Buket, and Faik Budak. "Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve Paralysis." Turkish Journal Of Neurology 27, no. 3 (2021): 311–14. http://dx.doi.org/10.4274/tnd.2021.24922.

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11

Simon, Neil G., and Matthew C. Kiernan. "Precise correlation between structural and electrophysiological disturbances in MADSAM neuropathy." Neuromuscular Disorders 25, no. 11 (2015): 904–7. http://dx.doi.org/10.1016/j.nmd.2015.07.012.

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12

Neubauer, C., H. Gruber, J. Bäuerle, and K. Egger. "Ultrasonography of Multifocal Acquired Demyelinating Sensory and Motor Neuropathy (MADSAM)." Clinical Neuroradiology 25, no. 4 (2015): 423–25. http://dx.doi.org/10.1007/s00062-014-0364-9.

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13

Beecher, Grayson, Benjamin M. Howe, Shahar Shelly, et al. "Plexus MRI helps distinguish the immune-mediated neuropathies MADSAM and MMN." Journal of Neuroimmunology 371 (October 2022): 577953. http://dx.doi.org/10.1016/j.jneuroim.2022.577953.

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14

Shelly, Shahar, John R. Mills, Jennifer M. Martinez-Thompson, et al. "IgM-gammopathy strongly favours immune treatable MMN and MADSAM over ALS." Journal of Neurology, Neurosurgery & Psychiatry 91, no. 3 (2019): 324–26. http://dx.doi.org/10.1136/jnnp-2019-321977.

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15

Martinez-Thompson, Jennifer M., Melissa R. Snyder, Michael Ettore, et al. "Composite ganglioside autoantibodies and immune treatment response in MMN and MADSAM." Muscle & Nerve 57, no. 6 (2018): 1000–1005. http://dx.doi.org/10.1002/mus.26051.

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16

Shanmugarajah, P., D. G. Rao, and M. Hadjivassiliou. "168 Rituximab in the treatment of Multifocal Acquired Demyelinating Sensory and Motor Neuropathy (MADSAM)." Journal of Neurology, Neurosurgery & Psychiatry 83, no. 3 (2012): e1.125-e1. http://dx.doi.org/10.1136/jnnp-2011-301993.210.

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17

Scheidl, Erika, Josef Böhm, Magdolna Simó, et al. "Ultrasonography of MADSAM neuropathy: Focal nerve enlargements at sites of existing and resolved conduction blocks." Neuromuscular Disorders 22, no. 7 (2012): 627–31. http://dx.doi.org/10.1016/j.nmd.2012.03.005.

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18

Kerasnoudis, Antonios. "Ultrasonography of MADSAM neuropathy: Focal nerve enlargements at sites of existing and resolved conduction blocks." Neuromuscular Disorders 22, no. 11 (2012): 1032. http://dx.doi.org/10.1016/j.nmd.2012.06.009.

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19

Merino-Ramírez, M., J. L. Llacer-Ortega, E. Llopis-San Juan, et al. "P228: A perplexing case of progressive “dangling arm” phenotype with hypoglossal involvement secondary to MADSAM." Clinical Neurophysiology 125 (June 2014): S109. http://dx.doi.org/10.1016/s1388-2457(14)50359-8.

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20

International, Journal of Medical Science and Innovative Research (IJMSIR). "Lewis-Sumner Syndrome Unraveled: A Comprehensive Case Study and Exploration." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 2 (2024): 57–60. https://doi.org/10.5281/zenodo.15378214.

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<strong>Abstract</strong> Lewis-Sumner syndrome (LSS), also known as multifocal acquired demyelinating sensory and motor neuropathy (MADSAM), is a rare variant of chronic inflammatory demyelinating polyneuropathy (CIDP). This abstract provides an overview of LSS, including its clinical presentation, diagnostic evaluation, and management strategies, based on current literature and a case report. LSS is characterized by asymmetric involvement of multiple peripheral nerves, leading to sensory and motor deficits that often present in a patchy distribution. Patients typically report progressive wea

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21

Dörner, Marc, Frank Schreiber, Heike Stephanik, et al. "Peripheral Nerve Imaging Aids in the Diagnosis of Immune-Mediated Neuropathies—A Case Series." Diagnostics 10, no. 8 (2020): 535. http://dx.doi.org/10.3390/diagnostics10080535.

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Background: Diagnosis of immune-mediated neuropathies and their differentiation from amyotrophic lateral sclerosis (ALS) can be challenging, especially at early disease stages. Accurate diagnosis is, however, important due to the different prognosis and available treatment options. We present one patient with a left-sided dorsal flexor paresis and initial suspicion of ALS and another with multifocal sensory deficits. In both, peripheral nerve imaging was the key for diagnosis. Methods: We performed high-resolution nerve ultrasound (HRUS) and 7T or 3T magnetic resonance neurography (MRN). Resul

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22

Sinha, Anupam, and Madhuri Dholakia. "Poster 114 Multifocal Acquired Demyelinating Sensory and Motor (MADSAM) Neuropathy Secondary to Infliximab Infusion: A Case Report." PM&R 4 (October 2012): S229. http://dx.doi.org/10.1016/j.pmrj.2012.09.739.

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23

Sawada, M., and K. Nakao. "CMAP parameters in the diagnosis of classic form CIDP, MADSAM, and DADS: Usefulness of Erb's point stimulation." Journal of the Neurological Sciences 333 (October 2013): e466-e467. http://dx.doi.org/10.1016/j.jns.2013.07.1662.

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24

Yoshida, Shun, Akio Kikuchi, Maki Tateyama, et al. "A case of steroid-responsive MADSAM with late appearance of a partial conduction block in the forearm." Journal of Neurology 261, no. 4 (2014): 825–27. http://dx.doi.org/10.1007/s00415-014-7271-5.

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Chandra, Sadanandavalli Retnaswami, Venkata Raviteja Karru, M. A. Mukheem Mudabbir, Subashree Ramakrishnan, and Anitha Mahadevan. "Immune-mediated Neuropathies Our Experience over 3 Years." Journal of Neurosciences in Rural Practice 09, no. 01 (2018): 030–35. http://dx.doi.org/10.4103/jnrp.jnrp_376_17.

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ABSTRACT Introduction: Immune-mediated peripheral neuropathy is the term applied to a spectrum of peripheral nerve disorders where immune dysregulation plays a role. Therefore, they are treatable. We analyzed the cases seen in the past 3 years by us and evaluated the clinical, laboratory, and outcome parameters in these patients. Patients and Methods: Consecutive patients seen by the authors and diagnosed as immune-mediated neuropathy were analyzed for etiology, pathology, and outcome assessed. Results: A total of sixty patients, 31 acute and 29 chronic neuropathies, were identified. Their sub

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Tanaka, Kanta, Natsuko Ota, Yuzuru Harada, Ikko Wada, and Toshihiko Suenaga. "Normalization of sonographical multifocal nerve enlargements in a MADSAM patient following a good clinical response to intravenous immunoglobulin." Neuromuscular Disorders 26, no. 9 (2016): 619–23. http://dx.doi.org/10.1016/j.nmd.2016.06.008.

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27

Zerra Sasicha, Agestania, Idah Hadijah, and Nurul Aini. "Profil Pemasaran Madame Wang Secret Garden Kota Malang." Jurnal Inovasi Teknologi dan Edukasi Teknik 1, no. 3 (2021): 169–74. http://dx.doi.org/10.17977/um068v1n3p169-174.

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The purpose of this research was to get information about Madame Wang Secret Garden marketing profile that expected to be a reference for another business development in overcoming the tight competition of business in fashion. Based on observations and interviews, Madame Wang Secret Garden started from a small boutique in 2013 with offline and online marketing and merged the marketing system concept from boutique only to boutique-café in 2014. This makes Madame Wang Secret Garden more crowded because they both have a balanced and profitable reciprocity, so that Madame Wang Secret Garden boutiq

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Munasinghe, Hasini, Bimsara Senanayake, Ishani Rajapakshe, Sudath Ravindra, Sudath Gunasekara, and Chulika Makawita. "Differentiating multifocal acquired demyelinating sensory and motor neuropathy (MADSAM) without sensory loss from multifocal motor neuropathy (MMN): A case study." Journal of the Neurological Sciences 429 (October 2021): 118531. http://dx.doi.org/10.1016/j.jns.2021.118531.

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Nur Fitriani, Desy Melya, and Beta Asteria. "ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUASAN KONSUMEN PADA PRODUK SUNSCREEN MADAM GIE." Jurnal TAMBORA 7, no. 3 (2023): 42–52. http://dx.doi.org/10.36761/jt.v7i3.3433.

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Studi berikut bertujuan untuk mengetahui factor yang bisa memberikan pengaruh pada rasa puas pembeli pada product sunscreen Madame Gie. Studi dilakukan dengan menerapkan pendekatan kuantitatif dengan mendistribusikan angket pada narasumber yang merupakan pengguna atau konsumen produk sunscreen Madame Gie. Hasil penelitian menunjukkan bahwa factor yang bisa memberikan pengaruh atas rasa puas pembeli pada product sunscreen Madame Gie adalah citra merk, mutu product dan pendapat mengenai biaya. Pencitraan merk memiliki pengaruh yang baik dan substansial terhadap rasa puas pembeli, artinya apabila

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Basri, Hasan. "Social condition of japanense geisha as reflectd in short story Madame Butterfly by John Luther Long." COMMICAST 2, no. 1 (2021): 15. http://dx.doi.org/10.12928/commicast.v2i1.2731.

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In this undergraduate thesis, the writer discusses short story Madam Butterfly written by John Luther Long. This study is aimed: (1) to describe the Geisha social life condition in Japanese society as reflected in Madame Butterfly (2) to describe the social class in Japanese society in 1903s as reflected in Madam Butterfly. In doing this research, the writer uses descriptive qualitative method which refers to description of things, characters, meaning and symbols. There are two types of data in this study.The findings of the research show that Geisha in Japan through Cho Cho San the main chara

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Koprušáková, M. Turčanová, M. Grofik, P. Jungová, J. Chandoga, and E. Kurča. "18-Hereditary sensory-motor neuropathy CMT 1C caused by a novel mutation in LITAF gene overlapped with an immune mediated asymmetric chronic inflammatory neuropathy (MADSAM)." Clinical Neurophysiology 129, no. 4 (2018): e11. http://dx.doi.org/10.1016/j.clinph.2018.01.038.

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Brahem, M., R. Sarraj, O. Jomaa, et al. "POS0982 UNUSUAL PRESENTATION OF LEWIS-SUMNER SYNDROME IN ELDERLY SIMULATING POLYMYOSITIS AND POLYMYALGIA RHEUMATICA." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 807.1–807. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2427.

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BackgroundLewis-Sumner syndrome (LSS) or multifocal acquired demyelinating sensory and motor neuropathy (MADSAM) is an atypical form of chronic inflammatory demyelinating polyneuropathy (CIDP). This rare disease is characterized by a predominantly distal, asymmetric weakness mostly affecting the upper limbs and motor dysfunction with adult onset. Diagnosis can be difficult to establish if the clinical presentation is atypical and frequently simulates inflammatory myopathy.Objectives:MethodsWe report a rare case of LSS in an old patient with unusual clinical aspects.ResultsA 70-year-old female

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Shyjan, A. M., M. Bertagnolli, C. J. Kenney, and M. J. Briskin. "Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences." Journal of Immunology 156, no. 8 (1996): 2851–57. http://dx.doi.org/10.4049/jimmunol.156.8.2851.

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Abstract The mucosal vascular addressin, mucosal addressin cell adhesion molecule-1 (MAdCAM-1), is an Ig family adhesion receptor preferentially expressed by venular endothelial cells at sites of lymphocyte extravasation in murine mucosal lymphoid tissues and lamina propria. MAdCAM-1 specifically binds both human and mouse lymphocytes that express the homing receptor for Peyer's patches, the integrin alpha 4 beta 7. Functional expression cloning was used to isolate a cDNA from a macaque mesenteric lymph node library that encodes the homologue to murine MAdCAM-1. The macaque cDNA was subsequent

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Perrone, Ian, Claudia Cicala, Fatima Nawaz та ін. "MAdCAM signaling through integrin α4β7 modulates surface expression of CCR5 and markers of CD4+ T cell activation." Journal of Immunology 196, № 1_Supplement (2016): 207.13. http://dx.doi.org/10.4049/jimmunol.196.supp.207.13.

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Abstract Integrin α4β7 mediates homing of lymphocytes, including CD4+ T cells, to gut-associated lymphoid tissue (GALT) through an interaction with Mucosal Addressin Cell Adhesion Molecule (MAdCAM), expressed on gut endothelial venules. MAdCAM facilitates rolling adhesion of CD4+ T lymphocytes along the gut endothelium prior to extravasation. Previous work also indicates that MAdCAM interactions with α4β7 provide a co-stimulatory signal to T cells. α4β7+/CD4+ T cells are a preferred target of HIV during the acute phase of infection. We hypothesized that signaling through α4β7 via MAdCAM render

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Andrews, Omozusi E., Donald Van Ryk, Aftab Ansari, Claudia Cicala, Anthony Fauci, and James Arthos. "MAdCAM as a potential biomarker of HIV-induced inflammation." Journal of Immunology 196, no. 1_Supplement (2016): 208.15. http://dx.doi.org/10.4049/jimmunol.196.supp.208.15.

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Abstract HIV causes a slowly progressive immunodeficiency disease via depletion of helper T cells and other immune cells, eventually resulting in AIDS. Currently, no effective vaccine exists for HIV. Acute HIV infection is associated with viral replication in, and of destruction of gut tissues. A key subset of gut-homing immune cells, CD4+ T cells expressing the integrin receptor α4β7, are highly susceptible to HIV infection. α4β7+/CD4+T cells gain entry to gut tissues by binding to MAdCAM, a receptor that is expressed on the surface of endothelial cells that line gut-associated lymphoid tissu

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Oshima, Tadayuki, Kevin P. Pavlick, F. Stephen Laroux, et al. "Regulation and distribution of MAdCAM-1 in endothelial cells in vitro." American Journal of Physiology-Cell Physiology 281, no. 4 (2001): C1096—C1105. http://dx.doi.org/10.1152/ajpcell.2001.281.4.c1096.

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Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is a 60-kDa endothelial cell adhesion glycoprotein that regulates lymphocyte trafficking to Peyer's patches and lymph nodes. Although it is widely agreed that MAdCAM-1 induction is involved in chronic gut inflammation, few studies have investigated regulation of MAdCAM-1 expression. We used two endothelial lines [bEND.3 (brain) and SVEC (high endothelium)] to study the signal paths that regulate MAdCAM-1 expression in response to tumor necrosis factor (TNF)-α using RT-PCR, blotting, adhesion, and immunofluorescence. TNF-α induced both MAdCA

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37

Sikorski, E. E., R. Hallmann, E. L. Berg, and E. C. Butcher. "The Peyer's patch high endothelial receptor for lymphocytes, the mucosal vascular addressin, is induced on a murine endothelial cell line by tumor necrosis factor-alpha and IL-1." Journal of Immunology 151, no. 10 (1993): 5239–50. http://dx.doi.org/10.4049/jimmunol.151.10.5239.

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Abstract The specificity of lymphocyte homing from the blood into a tissue is determined in part by complementary pairs of adhesion receptors on lymphocytes and endothelial cells termed homing receptors and vascular addressins, respectively. The mucosal vascular addressin involved in lymphocyte homing to Peyer's patches is a 66-kDa glycoprotein, MAdCAM-1. Investigation of the regulation and molecular genetics of MAdCAM-1 have been hampered by the lack of a murine cell line expressing this adhesion molecule. We show herein using indirect immunofluorescence studies that MAdCAM-1 can be induced o

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Fatrina, Novina Yeni, and Yan Stevenson. "Perubahan Dan Keberlanjutan Tari Balanse Madam Di Lingkungan Masyarakat Nias Padang." Mudra Jurnal Seni Budaya 33, no. 1 (2018): 93. http://dx.doi.org/10.31091/mudra.v33i1.318.

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Tulisan berjudul “Perubahan dan Keberlanjutan Tari Balanse Madam di Lingkungan Masyarakat Nias Padang“ bertujuan untuk mengungkapkan perubahan tari Balanse Madam serta menganalisis keberlanjutannya. Tari Balanse Madam merupakan tarian kelompok yang terdiri dari pasangan penari laki-laki dan perempuan yang sudah menikah. Penampilannya diiringi secara live dengan alat musik barat seperti biola, gitar, tamburin, akordeon, dan set drum. Namun setelah banyak para pelaku seninya yang meninggal dunia, sehingga tari Balanse Madam mengalami perubahan. Perubahan terjadi pada penarinya, tidak harus orang

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Mizushima, Takashi, Makoto Sasaki, Tomoaki Ando та ін. "Blockage of angiotensin II type 1 receptor regulates TNF-α-induced MAdCAM-1 expression via inhibition of NF-κB translocation to the nucleus and ameliorates colitis". American Journal of Physiology-Gastrointestinal and Liver Physiology 298, № 2 (2010): G255—G266. http://dx.doi.org/10.1152/ajpgi.00264.2009.

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Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is an important target in the treatment of inflammatory bowel disease (IBD). Recently, treatment of IBD with an antibody to α4β7-integrin, a ligand for MAdCAM-1, has been an intense focus of research. Our aim was to clarify the mechanism by which MAdCAM-1 is regulated via angiotensin II type 1 receptor (AT1R), and to verify if AT1R might be a novel target for IBD treatment. The role of AT1R in the expression of MAdCAM-1 in SVEC (a murine high endothelial venule cell) and MJC-1 (a mouse colonic endothelial cell) was examined followi

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Fritsche, Jana, Markus Moser, Stefan Faust, et al. "Molecular cloning and characterization of a human metalloprotease disintegrin— a novel marker for dendritic cell differentiation." Blood 96, no. 2 (2000): 732–39. http://dx.doi.org/10.1182/blood.v96.2.732.

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Abstract The 1,25-dihydroxyvitamin D3(1,25- [OH]2VD3) modulates the differentiation of monocytic cell lines and monocytes (MOs) in vitro. Up to now several target genes of 1,25(OH)2VD3have been described in monocytic cell lines; however, little is known about target genes in primary MOs. With the Differential Display technique, we found a transcript up-regulated by 1,25(OH)2VD3 in short-term cultured human blood MOs, which we called MADDAM (metalloprotease and disintegrin dendritic antigen marker; EMBL/GenBank/DDBJ accession no. Y13786). Northern blot analysis confirmed this result and reveal

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Fritsche, Jana, Markus Moser, Stefan Faust, et al. "Molecular cloning and characterization of a human metalloprotease disintegrin— a novel marker for dendritic cell differentiation." Blood 96, no. 2 (2000): 732–39. http://dx.doi.org/10.1182/blood.v96.2.732.014k11_732_739.

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The 1,25-dihydroxyvitamin D3(1,25- [OH]2VD3) modulates the differentiation of monocytic cell lines and monocytes (MOs) in vitro. Up to now several target genes of 1,25(OH)2VD3have been described in monocytic cell lines; however, little is known about target genes in primary MOs. With the Differential Display technique, we found a transcript up-regulated by 1,25(OH)2VD3 in short-term cultured human blood MOs, which we called MADDAM (metalloprotease and disintegrin dendritic antigen marker; EMBL/GenBank/DDBJ accession no. Y13786). Northern blot analysis confirmed this result and revealed a sign

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42

Viney, J. L., S. Jones, H. H. Chiu, et al. "Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif." Journal of Immunology 157, no. 6 (1996): 2488–97. http://dx.doi.org/10.4049/jimmunol.157.6.2488.

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Abstract The leukocyte integrin receptor, alpha 4 beta 7, and the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) are postulated to be important in regulating lymphocyte trafficking to normal intestine. Here we provide the first description of MAdCAM-1 expression in inflamed intestine. Using mouse models of experimentally induced colitis, we show a concordant increase in MAdCAM-1 expression associated with increased cellular infiltrates in areas of intestinal inflammation. To understand more of the molecular nature of the interactions between MAdCAM-1 and its leukocyte ligand, the alpha

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Ogawa, Hitoshi, David G. Binion, Jan Heidemann, et al. "Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells." American Journal of Physiology-Cell Physiology 288, no. 2 (2005): C272—C281. http://dx.doi.org/10.1152/ajpcell.00406.2003.

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Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is a homing receptor preferentially expressed on gut-associated endothelial cells that plays a central role in leukocyte traffic into the mucosal immune compartment. Although the molecular mechanisms underlying endothelial ICAM-1 or E-selectin expression have been intensively investigated, the mechanisms that regulate human MAdCAM-1 expression have not been defined. We report MAdCAM-1 gene and protein expression in primary cultures of human intestinal microvascular endothelial cells (HIMEC) that was not demonstrated in human umbilical vein

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Briskin, M. J., L. Rott, and E. C. Butcher. "Structural requirements for mucosal vascular addressin binding to its lymphocyte receptor alpha 4 beta 7. Common themes among integrin-Ig family interactions." Journal of Immunology 156, no. 2 (1996): 719–26. http://dx.doi.org/10.4049/jimmunol.156.2.719.

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Abstract The mucosal vascular addressin, MAdCAM-1, is an Ig family adhesion receptor preferentially expressed by venular endothelial cells at sites of lymphocyte extravasation in mucosal lymphoid tissues and lamina propria. MAdCAM-1 binds the lymphocyte homing receptor for Peyer's patches, the integrin alpha 4 beta 7. We describe a point mutation within the first Ig domain of MAdCAM-1 that abolishes activation-independent alpha 4 beta 7 binding. This point mutation resides within an eight-amino acid motif with homology to sequences important for the integrin binding ability of the related vasc

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Hakim, Arif Rahman. "KISAH LAKI-LAKI YANG MENIADA: TELAAH AKAR KATA DAN MAKNA MADAM DALAM TRADISI MIGRASI URANG BANJAR (THE TALE OF THE MAN WHO DISAPPEARED: STUDY OF ROOT WORD AND MEANING OF MADAM IN BANJARESE MIGRATION TRADITION)." JURNAL BAHASA, SASTRA, DAN PEMBELAJARANNYA 14, no. 1 (2024): 14. https://doi.org/10.20527/jbsp.v14i1.17044.

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AbstractThe Tale of The Man Who Disappeared: Study of Root Word and Meaning of Madam in Banjarese Migration Tradition. This article examines the tradition of Banjarese migration called madam. The background of the article starts from the problem that there is no study on the Banjarese migration that focuses on discussing the etymology and meaning of madam. This issue indicates that the fundamentals in understanding the madam tradition have not been well developed. Based on this background, the purpose of this article is to conduct a comprehensive research on the study of the etimological root

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Baran, Anna, Julia Nowowiejska, Tomasz W. Kamiński, Julita A. Krahel, and Iwona Flisiak. "Circulating MAdCAM-1 and ITGB7 in Patients with Plaque Psoriasis and Eruptive Lichen Planus—Preliminary Data." Biology 10, no. 11 (2021): 1129. http://dx.doi.org/10.3390/biology10111129.

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Plaque psoriasis (PSO) and lichen planus (LP) are skin diseases with some similarities in pathogenesis, comorbidities, and clinical presentation. Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) and its ligand, α4β7 integrin, are involved in inflammatory bowel diseases and liver dysfunctions, which occur more frequently in PSO and LP. Serum MAdCAM-1 and ITGB7 levels in patients with plaque PSO and eruptive LP have never been studied before. The study included 42 patients with PSO, 13 with LP, and 23 controls. Serum molecules levels were evaluated using the immune–enzymatic method. ITGB7 c

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Bozovic, Ratko. "The semiotic code of 'comrade' and 'mister'." Sociologija 51, no. 3 (2009): 279–90. http://dx.doi.org/10.2298/soc0903279b.

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The paper analyzes the meaning of expressions (terms) 'comrade' and 'mister', especially with respect to established socio-political orders. What is at issue are the differences between communicative communities based on different mutual understandings among citizens by using expressions 'comrade' and 'mister', i.e. female 'comrade' and 'madam' ('miss'), within the framework of certain semiotic code or codes. Special emphasis is put on the ambivalences of communist ideology regarding the mandatory introduction of 'comrade' as the only permitted form of address ('we are all comrades'), while th

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Waliszewski, Mia, Fatima Nawaz, Claudia Cicala та ін. "Anti-α4β7 mAb prevents MAdCAM-1-mediated activation and HIV replication in CD4+ T cells". Journal of Immunology 196, № 1_Supplement (2016): 208.11. http://dx.doi.org/10.4049/jimmunol.196.supp.208.11.

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Abstract HIV-1 preferentially infects α4β7+ CD4+ T cells, causing irreversible depletion of these cells in gut-associated lymphoid tissue (GALT) during the acute phase of infection. α4β7 mediates homing of CD4+ T cells to GALT through an interaction with mucosal addressin cell adhesion molecule-1 (MAdCAM-1), expressed on gut endothelial venules. In a rhesus macaque model of HIV transmission, administration of an anti-α4β7 mAb protected GALT from SIV infection. The mechanism(s) underlying this protection are poorly understood. We hypothesized that the anti-α4β7 mAb prevents MAdCAM mediated co-s

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Picarella, D., P. Hurlbut, J. Rottman, X. Shi, E. Butcher, and D. J. Ringler. "Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells." Journal of Immunology 158, no. 5 (1997): 2099–106. http://dx.doi.org/10.4049/jimmunol.158.5.2099.

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Abstract Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an adhesion protein expressed on endothelium in mucosal tissues that has been shown to play an important role in the selective homing of lymphocytes to intestinal mucosa and associated lymphoid tissue. To determine whether MAdCAM-1 or its ligand alpha 4 beta 7 would be appropriate targets for therapeutic intervention in gut-associated inflammation, we tested the ability of rat mAbs specific for beta 7 integrin and MAdCAM-1 to inhibit chronic colonic inflammation in scid mice reconstituted with CD4+ T cells enriched for the CD45R

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Szabo, M. C., E. C. Butcher, and L. M. McEvoy. "Specialization of mucosal follicular dendritic cells revealed by mucosal addressin-cell adhesion molecule-1 display." Journal of Immunology 158, no. 12 (1997): 5584–88. http://dx.doi.org/10.4049/jimmunol.158.12.5584.

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Abstract Follicular dendritic cells (FDC) in the mucosal lymphoid organs, Peyer's patches (PP), display mucosal vascular addressin-cell adhesion molecule-1 (MAdCAM-1). MAdCAM-1 decorates interlacing dendritic cells throughout PP follicles and is accentuated on FDC of the germinal center (GC) light zone and on "junctional" dendritic cells overlapping the B/T border and subepithelial dome region, sites associated with microenvironmental homing decisions. In contrast, MAdCAM-1 is rarely displayed by coronal or junctional FDC in peripheral lymph node follicles and is largely confined to the GC aft

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