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Dissertations / Theses on the topic 'MaeIII'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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1

Reyburn, Hugh Thomson. "Immune responses to maedi-visna virus." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/29962.

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The immune response to maedi-visna virus has been investigated, both in persistently infected sheep and in the acute phase of the primary immune response to infection with maedi-visna. Maedi-visna infected sheep develop detectable levels of anti-viral antibody by 4-6 weeks after experimental infection. These antibodies are directed against the envelope and core structural proteins of the virus and initially are of the IgM isotype, but later switch to IgG. These IgG anti-visna antibodies are restricted to the IgG<SUB>1</SUB> subclass. The functional significance of this isotypic restriction of
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2

McNeilly, Tom N. "Respiratory transmission of maedi-visna virus." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/30497.

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Using an ovine tracheal organ culture model it was found that tracheal mucosa was infectable with MVV, but this infection was inefficient and non-productive, with doses of ≥ 1 x 10<sup>5</sup><sub> </sub>TCID<sub>50</sub> required for detectable infection. Virus containing cells were located in a sub-epithelial location within 12 hours post-infection, but never in the tracheal epithelium. In addition, mechanical disruption of the epithelium resulted in a significant increase in virus uptake. These results suggest that tracheal epithelium acts as a barrier to MVV uptake, and is not a primary ta
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3

Sutton, Keith A. "Regulation of transcription in maedi-visna virus." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/30019.

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The ovine lentivirus maedi visna (MVV) is the prototypic lentivirus. MVV causes a chronic disease with a long incubation period. Infection results in a number of symptoms the most notable being dyspnoea and wasting. The lesions are characterised by a massive mononuclear cell infiltration. Following onset of clinical disease there is a progressive increase in symptoms until death occurs. Replication of MVV within the infected animal appears limited throughout the course of infection and virus replication is not readily detected <I>in vivo</I> even within the pathological lesions. <I>In vivo</I>
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4

Maevis, Volker [Verfasser]. "Hairy cell leukemia : Short review, today’s recommendations and outlook / Volker Maevis." Bonn : Universitäts- und Landesbibliothek Bonn, 2015. http://d-nb.info/107727100X/34.

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5

Ryan, Susanna Ruth. "Infection of dendritic cells by maedi visna virus." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624356.

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6

Singh, Inderpal. "Immune recognition of antigens on maedi-visna virus-infected cells." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624207.

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7

Carey, Nessa. "Studies on the extracellular envelope glycoprotein of maedi-visna virus." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/30083.

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The extracellular envelope glycoprotein (gp135) of maedi-visna virus interacts with cellular receptor molecules and is the major target of neutralsing antisera <i>in vivo</i>. Antigenic drift of gp135 may have an important role in viral persistence. In order to begin to investigate the roles of different regions of gp135, yeast and bacterial expression systems were used to generate recombinant protein and gp135 was expressed as 3 overlapping fragments. There have been no published reports of expression of recombinant gp135 proteins. By using the proteins to screen sera from infected sheep it w
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8

Cousens, Christina A. M. "Membrane fusion and the transmembrane envelope glycoprotein of maedi visna virus." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/29714.

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The transmembrane envelope glycoprotein, gp46 of maedi visna virus (MVV) was proposed to mediate membrane fusion between the virus and cell and between infected and uninfected cells on the basis of analogy with other viruses. In order to look at the relationship between fusion and gp46, which is difficult to purify to quantity from virus preparations, recombinant gp46 (rpg46) was made. This first required cloning of the part of the MVV (strain EV1) <I>env</I> gene which encodes gp46. Sequence comparison with other viruses showed that gp46 is a typical transmembrane fusion protein, with a hydro
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9

Collie, D. David S. "Pathophysiological correlations in maedi, a chronic lymphoid interstitial pneumonia of sheep." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/30682.

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This thesis describes an investigation into the pathophysiological mechanism responsible for inducing lung functional deficits in maedi. As a prelude to establishing the nature of the functional deficit in maedi, repeated measurements of static lung compliance (Cst), lung distensibility (<I>K</I>), effective alveolar volume (VA,eff) and transfer factor for carbon monoxide (TL,CO,'sb') were made in anaesthetised control sheep, seronegative for MVV, over a period of 5 months. This study furnished regression equations and prediction intervals for lung function indices in normal sheep using bodywe
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10

Zhang, Zhidong. "Regulation of maedi-visna virus and cytokine gene expression in macrophages." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/30055.

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Macrophages are proposed to play a central role in Maedi-visna virus (MVV) infection as target cells. However, the level of MVV load in alveolar macrophages (AMs) and its correction with pulmonary lesions is unknown. Also it is not yet clear whether cytokine expression is dysregulated in macrophages infected with MVV. In addition, the effects of exogenous cytokines on MVV replication in macrophages have not been documented. The aims of this study were to determine. 1. the level of MVV DNA in AMs compared with blood monocytes in natural infection and assess the correlation of viral burden and r
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11

Rousselot, Christian. "Préparation d'anticorps monoclonaux contre le virus Visna maedi et leurs applications." Lyon 1, 1989. http://www.theses.fr/1989LYO10041.

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La visna maedi est un retrovirus de la sous-famille des lentivirus. Dans le but de mieux connaitre la structure du virus, et de developper un test elisa de competition, d'aide au diagnostic de la maladie, nous avons developpe et produit des anticorps monoclonaux, vis-a-vis du virus visna, souche k1514. Le caractere aleatoire de l'obtention et du choix des anticorps monoclonaux ne nous a permis de selectionner un couple d'anticorps convenant a la realisation du test elisa de competition. Les anticorps monoclonaux obtenus, nous permettent aujourd'hui de detecter le virus dans les cellules infect
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12

Duval, Raphaël. "Expression des différentes voies apoptotiques induites par le rétrovirus Visna." Limoges, 2003. http://aurore.unilim.fr/theses/nxfile/default/f582e17f-b945-4741-b8f5-5f4c49dcfae0/blobholder:0/2003LIMO330A.pdf.

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L'apoptose est un processus de mort cellulaire programmée, génétiquement contrôlé. Parmi les stimuli inducteurs d'apoptose, figurent certains agents pathogènes (virus, bactéries) et certains antibiotiques comme la staurosporine, sélectionnée comme témoin positif sur notre système cellulaire : les cellules primaires de plexus choroi͏̈de ovines. Le rétrovirus Visna est un Lentivirus, responsable d'encéphalopathie démyélinisante et de pneumopathie progressive chez les ovins et les caprins. Les cibles cellulaires du Visna sont essentiellement les monocytes/macrophages. Dans une première étape, nou
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13

Dungu-Kimbenga, Baptiste. "Study on the effects of a natural Maedi visna virus infection on sheep productivity." Pretoria : [s.n.], 2009. http://upetd.up.ac.za/thesis/available/etd-01052007-100419/.

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14

Chŏng, Chin-sŏk. "Taehan Maeil Sinbo wa paesŏl Hanʼguk munje e taehan Yŏng-Il oegyo /". Sŏul : Nanam, 1987. http://books.google.com/books?id=qt_SAAAAMAAJ.

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Rev. and exp. ed. of Thesis (Ph. D)-- London School of Economics & Political Science.<br>Title on verso of t.p.: Ernest Thomas Bethell and his newspapers: The Daehan Maeil Sinbo and the Korea Daily News : The Korean problem in Anglo-Japanese relations, 1904-1910. Includes bibliographical references (p. 503-524.) and index.
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15

Rosa, Eric Pivari [UNESP]. "Soroprevalência da pneumonia progressiva ovina (Maedi-Visna) na região de Botucatu-SP." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/89264.

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Made available in DSpace on 2014-06-11T19:23:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-07-12Bitstream added on 2014-06-13T18:48:25Z : No. of bitstreams: 1 rosa_ep_me_botfmvz.pdf: 165229 bytes, checksum: 697ad7c59c3b82def1308133fdf3f932 (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>O presente estudo visou determinar a soroprevalência da pneumonia progressiva ovina na região de Botucatu mediante prova de imunodifusão em gel de agar (IDGA). Foram avaliadas 400 amostras de soro sangüíneo de ovinos de oito propriedades de corte, com criação em si
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16

Rosa, Eric Pivari. "Soroprevalência da pneumonia progressiva ovina (Maedi-Visna) na região de Botucatu-SP /." Botucatu : [s.n.], 2007. http://hdl.handle.net/11449/89264.

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Orientador: Rogério Martins Amorim<br>Banca: Márcio Garcia Ribeiro<br>Banca: Júlio Augusto Naylor Lisboa<br>Resumo: O presente estudo visou determinar a soroprevalência da pneumonia progressiva ovina na região de Botucatu mediante prova de imunodifusão em gel de agar (IDGA). Foram avaliadas 400 amostras de soro sangüíneo de ovinos de oito propriedades de corte, com criação em sistema semi-intensivo, de diferentes municípios da região. Nenhuma das amostras de soro foi reagente na prova de IDGA. Com base nos resultados obtidos, foi verificada uma discordância com estudos realizados em outros est
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17

Ebrahimi, Bahram. "Role of brain microglial cells in neuropathogenesis of Maedi-Visna virus infection." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/29745.

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The role of microglial cells in visna neuropathology was studied by use of highly enriched (purity > 98%) primary cultures. Ovine microglial cells showed extensive phenotypic similarities with cells of the monocyte/macrophage lineage. However, they also exhibited distinct morphological characteristics. Further, ovine microglial cultures could be productively infected with MVV <I>in vitro. </I>This was demonstrated by a combination of immunocytochemical and molecular assays. Assessment of ovine cytokine production in MVV-infected microglial cells <I>in vitro</I> demonstrated significant increas
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18

Cozon, Grégoire. "Activation macrophagique et infection lentivirale dans le modèle du virus Visna-Maedi." Lyon 1, 1992. http://www.theses.fr/1992LYO1H007.

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19

Tolu, Giuseppe. "Análise genómica da resistência ao maedi-visna vírus em ovelhas de raça sarda." Master's thesis, Universidade de Évora, 2021. http://hdl.handle.net/10174/30362.

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Maedi-Visna é um vírus difundido ao nível mundial que causa uma infeção persistente em ovinos com manifestações clínicas altamente variáveis, caracterizadas por lesões progressivas que afetam pulmões, úbere, articulações e sistema nervoso. As causas da difusão da infeção na Itália parecem estar correlacionadas à importância que a ovinocultura tem assumido nas últimas décadas para atender ao aumento da demanda por laticínios, e consequentemente ao aumento do número de ovinos criados e da produtividade. Além disso, os sistemas agrícolas tradicionais têm contribuído para a propagação do vírus, po
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20

Costa, Ubirajara Maciel da. "Obtenção e caracterização de células de membrana sinovial ovina transformadas pelo antígeno T do vírus símio 40: influência na variabilidade dos genes gag e env e do LTR dos vírus da artrite-encefalite caprina (CAEV) e maedi-visna (MVV) dos ovinos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2004. http://hdl.handle.net/10183/5095.

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Cultivos celulares podem ser utilizados para isolamento viral, caracterização de novas amostras virais e produção de imunobiológicos. Podem ser empregados cultivos celulares primários, secundários ou de linha. Estes últimos podem ser obtidos pela transformação física, química ou biológica de cultivos primários ou secundários. Para verificar a interação entre células transformadas com o Ag T do vírus símio 40 (SV40) e os Lentivírus de Pequenos Ruminantes (SRLV), amostras brasileiras de SRLV foram utilizadas para inoculação em cultivos celulares de membrana sinovial ovina transformados pelo Ag T
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21

MAZARIN, VERONIQUE. "Etude d'un gene precoce du lentivirus visna." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX22964.

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22

Lombardi, Adriana Longo [UNESP]. "Ocorrência de ovinos soropositivos para Maedi-Visna na região de Araçatuba-SP-Brasil." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/92212.

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Made available in DSpace on 2014-06-11T19:25:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-01-24Bitstream added on 2014-06-13T19:33:00Z : No. of bitstreams: 1 lombardi_al_me_araca.pdf: 210693 bytes, checksum: 8b1debf6cc18d982119fcb5ec5619147 (MD5)<br>A Secretaria de Defesa Agropecuária estabeleceu o controle e erradicação de Maedi-Visna no Brasil, que inclui o diagnóstico laboratorial e sacrifício dos animais positivos. Com o objetivo de se determinar a ocorrência de Maedi-Visna em ovinos na região de Araçatuba-SP, foram coletadas 444 amostras de sangue de ovinos com idade entre
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23

Ritchie, P. J. C. "Characterization of the external envelope glycoprotein of Maedi-Visna virus, an ovine lentivirus." Thesis, University of Edinburgh, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.661158.

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The envelope glycoproteins of Maedi-Visna virus consist of a surface glycoprotein (gp135) which is responsible for the characteristic spikes on the surface of the virion, and a transmembrane protein (gp41) whose function includes linkage to the surface glycoprotein, anchoring it to the virion envelope. The external glycoprotein is required for attachment to the host cell via a receptor molecule present on the surface of the cell. Cells of the macrophage lineage are the main target cells in MVV infection <I>in vivo. </I>The host humoral response is targeted to the surface glycoprotein resulting
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24

Lombardi, Adriana Longo. "Ocorrência de ovinos soropositivos para Maedi-Visna na região de Araçatuba-SP-Brasil /." Araçatuba : [s.n.], 2008. http://hdl.handle.net/11449/92212.

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Orientador: Luiz Cláudio Nogueira Mendes<br>Banca: Alexandre Secorun Borges<br>Banca: Roberto Soares de Castro<br>Resumo: A Secretaria de Defesa Agropecuária estabeleceu o controle e erradicação de Maedi-Visna no Brasil, que inclui o diagnóstico laboratorial e sacrifício dos animais positivos. Com o objetivo de se determinar a ocorrência de Maedi-Visna em ovinos na região de Araçatuba-SP, foram coletadas 444 amostras de sangue de ovinos com idade entre dois e 12 anos, de ambos os sexos e de diversas raças, em 20 propriedades desta região escolhidas aleatoriamente. Exame físico geral foi feito
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25

Bianchini, Stefano. "Buchi neri primordiali dalle bolle di vuoto." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/17660/.

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I buchi neri primordiali sono un ipotetico tipo di buchi neri formatosi poco dopo il Big Bang nei primi istanti di vita dell'universo. Tali buchi neri, non discendendo dall'evoluzione di una stella, possono abbracciare un ampissimo intervallo di masse il quale ipoteticamente va dalla massa di Plank a milioni di masse solari. L'intersse che circonda i PBH è anche dato dal fatto che le loro caratteristiche li rendono possibili candidati alla spiegazione della materia oscura come verrà discusso nella tesi. Tali oggetti hanno recentemente richiamato l'attenzione della comunità scientifica in quan
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26

Pyrah, I. T. G. "The dermal delayed type hypersensitivity reaction in sheep naturally infected with maedi-visna virus." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/30662.

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Maedi Visna virus (MVV) is the prototype lentivirus, capable of infecting cells of the monocyte/macrophage series in sheep. Infection is associated with pathological changes characterised by dysfunction of the cell mediated immune system. The work described in this thesis was undertaken to study <I>in vivo</I> cell mediated immune function in sheep infected with MVV using the tuberculin driven delayed type hypersensitivity (DTH) reaction as the experimental system. The gross and immunohistological characteristics of the DTH were firstly evaluated in control sheep (CD4<SUP>+</SUP>, CD8<SUP>+</S
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27

Dungu-Kimbenga, B. "Study on the effects of a natural Maedi visna virus infection on sheep productivity." Diss., University of Pretoria, 2000. http://hdl.handle.net/2263/25380.

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A cohort study was conducted in order to measure the effect of the chronic indurative lymphocytic mastitis caused by the South African strain ofMaedi visna virus (SA-OMVV) on the pre-weaning growth of lambs born of naturally infected and uninfected ewes kept under similar conditions. 50 naturally infected ewes and 40 controls from an MVV-free source were purchased and kept separately. All ewes were of the same breed - the Dorper¬and 3 to 4 years old. From the adaptation period, through mating, pregnancy and lactation periods they were monitored for MVV antibodies and managed under similar cond
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28

Fotheringham, Michael William. "Expression and functional characterisation of the Rev gene product of Maedi Visna virus EV-1." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/29764.

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To compare the mode of action of NVV Rev with that of HIV-1 Rev, a series of functional assays were planned. The <I>rev </I>gene of a British isolate of MVV (EV-1) was cloned and sequenced. Recombinant Rev was expressed as a fusion protein in yeast and bacterial systems. Expression in yeast was characterised by a low product yield, due to the highly toxic nature of the Rev fusion protein. Alternative expression and purification protocols were unable to greatly improve the yield and purity of product. The bacterial pGEX system, in which Rev was fused to glutathione S-transferase (GSTRev), was e
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29

Cadoré, Jean-Luc. "Mécanismes des lésions pulmonaires au cours de l'infection du mouton par le virus Visna maedi." Lyon 1, 1995. http://www.theses.fr/1995LYO1T060.

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30

Schaller, Patrick. "Die Maedi-Visna-Virusinfektion in der Schweiz : eine Querschnittsstudie über Seroprävalenz und mögliche assoziierte Faktoren /." [S.l.] : [s.n.], 1994. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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31

Larrouturou, Sylvie. "Activité in vitro de substances antirétrovirales contre le virus visna-maedi : évaluation de plusieurs méthodes." Limoges, 1993. http://www.theses.fr/1993LIMO302B.

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32

Fernandes, Leíse Gomes. "Estudo sócio-epidemiológico das criações de ovinos e caprinos participantes de exposições agropecuárias do Rio Grande do Norte." Universidade Federal Rural do Semi-Árido, 2011. http://bdtd.ufersa.edu.br:80/tede/handle/tede/326.

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Made available in DSpace on 2016-08-15T20:31:01Z (GMT). No. of bitstreams: 1 LeiseGF_DISSERT.pdf: 911224 bytes, checksum: 2b33fb730a32f99a89b61b150f1d1b49 (MD5) Previous issue date: 2011-08-12<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The objective of this study was to describe characteristics of systems creations of goats and sheep farming exhibitions of participants, and to study the occurrence of Brucella ovis infections in sheep and lentivirus, and leptospirosis caseous lymphadenitis in goats and sheep and their risk factors. Carried out 64 questionnaires, examine
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33

ECOCHARD, DENISE. "Immunite humorale au cours des infections lentivirales : caracterisation de la reponse anticorps induite par le virus visna-maedi (lentivirus apparente aux virus de l'immunodeficience acquise)." Lyon 1, 1990. http://www.theses.fr/1990LYO1M168.

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34

Wu, Changxin. "Ovine MHC class I and mapping of MHC class I restricted CTL epitopes in Maedi Visna virus." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612854.

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35

Begara, Isabel M. "Immunopathological studies in the ovine lung during the course of natural and experimental maedi-visna virus infection." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/29904.

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The pulmonary immunopathology of maedi-visna virus (MVV) infection was investigated, firstly performing <I>in vivo</I>, and <I>in vitro</I> studies and secondly, by reproducing the disease experimentally. Peripheral blood (PB) and bronchoalveolar lavage fluid (BALF) cells of naturally MVV-infected and control sheep were phenotypically characterised by using single-colour flow cytometry. BALF from MVV-infected sheep had significantly increased percentages of lymphocytes, neutrophils and CD8<SUP>+</SUP> lymphocytes, decreased percentages of CD4<SUP>+</SUP> and CD5<SUP>+</SUP> lymphocytes (p<0.05
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36

Rey, Olivier. "Etude des interactions entre les macrophages dérivé de la moelle osseuse ovine et le virus Maedi Visna /." Berne, 1993. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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37

Scherf, Claudia [Verfasser]. "Untersuchungen zum Einfluß einer Maedi-Infektion auf die Funktion und die Morphologie der Lungen verschiedener Schafrassen / Claudia Scherf." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2010. http://d-nb.info/1009653016/34.

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38

Marques, Ana Paula Ribeiro. "Caracterização soroepidemiológica da infecção por vírus Maedi-Visna e Brucella ovis em ovinos no Estado de Minas Gerais." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/SSLA-7VGHRK.

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The prevalence of the infection by Maedi-Visna lentivirus (MVV) and Brucella ovis was determine and characterized epidemiologic serum proprieties with sheep flock distributed in nine regional areas (Campo das Vertentes, Central Mineira, Metropolitana de Belo Horizonte, Noroeste de Minas, Oeste de Minas, Sul/Sudeste de Minas, Triângulo/Alto Paranaíba, Vale do Rio Doce and Zona da Mata) of 12 regional areas of Minas Gerais state. The samples were gather in 2002 and in every propriety was applied one detail questionnaire. 833 ovine serum samples was test through the agar gel imunodifusion techniq
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39

Cortez, Romero César. "Eléments d'appréciation du risque de transmission du virus du Maedi visna (MVV) lors du transfert embryonnaire chez la brebis." Rennes, Agrocampus, 2006. http://www.theses.fr/2006NSARB172.

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Aujourd'hui, les biotechnologies de la reproduction sont essentielles pour favoriser l'amélioration du patrimoine génétique de l'espèce ovine. Cependant, le potentiel de diffusion des agents infectieux de ces techniques doit être évalué. L'objectif de ce travail est d'apporter des éléments, permettant d'évaluer le risque de transmission du lentivirus ovin, lors de la réalisation de transferts embryonnaires, à partir d'embryons produits in vivo ou in vitro. Ceci, afin d'apprécier les possibilités de produire du matériel indemne, à partir de femelles infectées. Cette étude démontre pour la premi
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40

Legastelois, Isabelle. "Rôle des cytokines proinflammatoires dans la physiopathologie pulmonaire due à l'infection par le lentivirus Visna-Maedi chez le mouton." Lyon 1, 1997. http://www.theses.fr/1997LYO1T018.

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41

Al-Maeeni, Sara Salman Hassan [Verfasser]. "Re-engineering of Machine Tools in the Context of Sustainability and Industry 4.0 : Case Study: Rotary Draw Bending Machines / Sara Salman Hassan Al-Maeeni." Düren : Shaker, 2021. http://d-nb.info/1227824246/34.

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42

Neuveut, Cnristine. "Contribution à l'étude des protéines virales et cellulaires impliquées dans le contrôle de l'expression des lentivitus HIV-I et maedi-visna." Aix-Marseille 2, 1993. http://www.theses.fr/1993AIX22022.

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Nous nous sommes interesses aux facteurs cellulaires et viraux responsables de la modulation de l'expression des lentivirus hiv-i et maedi-visna dans la lignee monocytaire. Dans la premiere partie de ce travail, nous avons montre que l'infection de macrophages par le virus hiv-i induisait l'apparition nucleaire de facteurs apparentes au facteur nf-kb. L'induction de ces facteurs semble dependre de l'etat de maturation de la cellule. Ces resultats montrent que le virus peut modifier l'environnement moleculaire de la cellule et notamment mimer des mecanismes d'activation/differenciation qui cond
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43

Vorster, J. H. (Jan Harm). "A study of the sensitivity and specificity of an immunoperoxidase technique for the diagnosis of maedi-visna virus infection in sheep." Diss., University of Pretoria, 2002. http://hdl.handle.net/2263/26708.

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In this study the sensitivity and specificity of an immunoperoxidase technique for the detection of lentiviral protein in formalin-fixed lung tissues of sheep were assessed. Formalin-fixed specimens of lungs of 52 sheep originating from two different infected flocks and formalin-fixed lung specimens of 20 sheep from a third, non-infected flock were selected. Multiple sections from each animal were stained with a monoclonal antibody against Maedi-Visna Virus (MVV) antigen. Control sections were stained with an irrelevant antibody, and without antibody, respectively in both the positive and nega
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44

TEIXEIRA, Whaubtyfran Cabral. "Soroprevalência de lentiviroses de pequenos ruminantes e caracterização dos rebanhos caprinos e ovinos no estado do Maranhão, Brasil." Universidade Federal Rural de Pernambuco, 2012. http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5900.

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Submitted by (edna.saturno@ufrpe.br) on 2016-11-09T12:16:52Z No. of bitstreams: 1 Whaubtyfran Cabral Teixeira.pdf: 1328857 bytes, checksum: 071dbd504f948b5d47ca8a7a13339069 (MD5)<br>Made available in DSpace on 2016-11-09T12:16:52Z (GMT). No. of bitstreams: 1 Whaubtyfran Cabral Teixeira.pdf: 1328857 bytes, checksum: 071dbd504f948b5d47ca8a7a13339069 (MD5) Previous issue date: 2012-02-09<br>Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>The aim of the present study was to determine the s
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45

Chong, Chin-Sok. "The Korean problem in Anglo-Japanese relations 1904-1910 : Ernest Thomas Bethell and his newspapers, the Daehan Maeil Sinbo and the Korea Daily News." Thesis, London School of Economics and Political Science (University of London), 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245422.

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46

McLean, Rebecca Kathryn. "Development of a novel lentiviral vaccine vector and characterisation of in vitro immune responses." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31135.

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Vaccines are a highly effective means of preventing infectious disease. However, for many diseases of livestock the available vaccines are ineffective or sub-optimal. This is partly due to challenges surrounding the specific targeting of antigen presenting cells (APCs). In order to improve the delivery of protective antigens to host APCs, a novel lentiviral vector derived from visna / maedi virus (VMV) has been developed. Initial characterisation using an enhanced green fluorescent protein (eGFP) reporter transgene found that the novel VMV vector efficiently transduced a wide range of cell lin
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47

Rudys, Saulius. "Plačiajuostės dielektrinės spektroskopijos metodų tobulinimas, tiriant (1-x)(Na1/2 Bi1/2)TiO3 - xLa(Mg1/2 Ti1/2)O3 ir kitas medžiagas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20121001_093621-49513.

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Šiame darbe nagrinėjamos galimybės patobulinti plačiajuostės dielektrinės spektroskopijos metodus naudojant skaitmeninius ir analitinius daugelio modų dielektrinės skvarbos skaičiavimo metodus, tiriami (1-x)(Na1/2 Bi1/2)TiO3 - xLa(Mg1/2 Ti1/2)O3 (NBT-LMT) keramikų grupės laidumo ypatumai. Nagrinėjama galimybė pritaikyti HFSS skaitmeninio modeliavimo programą dielektrinės spektroskopijos tikslams. Naudojant šią programinę įrangą, apskaičiuojama dielektrinė ir magnetinė skvarbos komplikuotiems mikrojuostelinės linijos ir dalinai užpildyto bangolaidžio matavimo grandinių atvejams. Pateikiami pato
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48

Rudys, Saulius. "Development of the methods of broadband dielectric spectroscopy by investigating (1-x)(Na1/2 Bi1/2)TiO3 - xLa(Mg1/2 Ti1/2)O3 and other materials." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20121001_093609-73724.

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Šiame darbe nagrinėjamos galimybės patobulinti plačiajuostės dielektrinės spektroskopijos metodus naudojant skaitmeninius ir analitinius daugelio modų dielektrinės skvarbos skaičiavimo metodus, tiriami (1-x)(Na1/2 Bi1/2)TiO3 - xLa(Mg1/2 Ti1/2)O3 (NBT-LMT) keramikų grupės laidumo ypatumai. Nagrinėjama galimybė pritaikyti HFSS skaitmeninio modeliavimo programą dielektrinės spektroskopijos tikslams. Naudojant šią programinę įrangą, apskaičiuojama dielektrinė ir magnetinė skvarbos komplikuotiems mikrojuostelinės linijos ir dalinai užpildyto bangolaidžio matavimo grandinių atvejams. Pateikiami pato
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49

Assis, Anna Paula Menezes Vianna de. "Evidência sorológica da ocorrência de Lentivírus (Maedi visna/ Artrite Encefalite Caprina) em rebanhos nos estados de Minas Gerais, Rio de Janeiro, Bahia e Ceará de 1991 a 1993." Universidade Federal de Minas Gerais, 1994. http://hdl.handle.net/1843/BUOS-8PLL6G.

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A evidência sorológica de lentivírus (Maedi Visna/Artrite Encefalite Caprina) foi constatada através de exame de 1.601 soros caprinos provenientes de criatórios de Minas Gerais, Rio de Janeiro, Bahia e Ceará, testados com "kit" de imunodifusão para Maedi Visna. Dos 1.601 soros testados 461 (28,79 %) apresentaram reação positiva. Do estado de Minas Gerais foram testados 615 soros apresentando 205 (33,33%) positivos ao teste. O estado do Rio de Janeiro apresentou 30 (29,70 %) soros positivos de 101 soros testados. De alguns criatórios da Bahia foram testados 117 soros que apresentaram resultado
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50

Yorinori, Eliane Harumi. "Características dos sistemas de produção de pequenos ruminantes e prevalências da artrite - encefalite caprina (CAE) e maedi - visna (MV) ovina, nas regiões norte e nordeste de Minas Gerais, 2000." Universidade Federal de Minas Gerais, 2001. http://hdl.handle.net/1843/BUDB-8BSHJ7.

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Com a finalidade de se determinar algumas das características dos sistemas de produção de pequenos ruminantes no Norte de Minas Gerais, em função de seu grande crescimento a partir de 1999, e para a obtenção de dados referentes à presença de lentivírus de pequenos ruminantes, foi realizado um levantamento epidemiológico em rebanhos caprinos e ovinos na Região Mineira do Nordeste, área de atuação da extinta SUDENE, abordando alguns dos principais elementos na base da cadeia produtiva. Constatou-se que 40,7% dos produtores adotam o regime de criação extensivo, voltado majoritariamente à produção
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