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Relevant bibliographies by topics / Magnesium stearate and micro crystalline cellulose

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Journal articles

Academic literature on the topic 'Magnesium stearate and micro crystalline cellulose'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Magnesium stearate and micro crystalline cellulose"

1

NIKAM, BHARAT ASHOK, and AMOL U. GAYKE. "FORMULATION DEVELOPMENT AND EVALUATION OF IMMEDIATE RELEASE TABLET OF PARACETAMOL AND ORPHENADRINE CITRATE BY DIRECT COMPRESSION METHOD." Journal of Science and Arts 22, no. 3 (2022): 735–54. http://dx.doi.org/10.46939/j.sci.arts-22.3-b04.

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The objective of this research work was to formulate, develop and evaluate immediate release tablet of paracetamol and orphenadrine citrate by direct compression method. Paracetamol which is antipyretic and orphenadrine citrate is skeletal muscle relaxant. The drug paracetamol and orphenadrine citrate was taken and formulated with different concentration of cross-povidone, mannitol, micro-crystalline cellulose, magnesium stearate and talc. Where cross-povidone as a superdisintegrant, mannitol as diluent, micro-crystalline cellulose as binder, magnesium stearate as lubricant and talc as a glida

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2

Staniforth, J. N., and H. A. Ahmed. "INFLUENCE OF TERNARY COMPONENTS ON COMPRESSIBILITY OF MICRO-CRYSTALLINE CELLULOSE FOLLOWING BLENDING WITH MAGNESIUM STEARATE." Journal of Pharmacy and Pharmacology 38, S12 (1986): 50P. http://dx.doi.org/10.1111/j.2042-7158.1986.tb14279.x.

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3

Rangu, Nirmala, and Gande Suresh. "Formulation and Evaluation of Nelfinavir Extended Release Trilayer Matrix Tablets by Design of Experiment." International Journal of Pharmaceutical Sciences and Nanotechnology 11, no. 5 (2018): 4259–68. http://dx.doi.org/10.37285/ijpsn.2018.11.5.6.

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The present study was aimed to develop once-daily controlled release trilayer matrix tablets of nelfinavir to achieve zero-order drug release for sustained plasma concentration. Nelfinavir trilayer matrix tablets were prepared by direct compression method and consisted of middle active layer with different grades of hydroxypropyl methylcellulose (HPMC), PVP (Polyvinyl Pyrrolidine) K-30 and MCC (Micro Crystalline Cellulose). Barrier layers were prepared with Polyox WSR-303, Xanthan gum, microcrystalline cellulose and magnesium stearate. Based on the evaluation parameters, drug dissolution profi

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4

Upadhyay, Uma, and KS Rathore. "FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF METFORMIN HYDROCHLORIDE." Pharmaceutical and Chemical Journal 1, no. 2 (2014): 5–13. https://doi.org/10.5281/zenodo.13691319.

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The aim of the current study is to design a sustained release matrix tablet of metformin HCl to maintain plasma level of drug for prolong period of time. Metformin HCl is antihyperglycemic agent used in the treatment of type II Non insulin dependent diabetes mellitus. Sustained release formulation of metformin HCl prolong drug absorption in the upper GI tract and permits once daily dosing in patient with type II diabetes mellitus. This newer formulation may enhance patient compliance compared to conventional immediate release metformin HCl. Metformin HCl present significant challenges due to i

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5

Megha, Pandey* Dr. Shilpa Gawande Dr. A. V. Chandewar. "Formulation And Development of Oral Fast Dissolving Tablets Using a Model Drug." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3892–905. https://doi.org/10.5281/zenodo.15493439.

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The aim of this study was to develop fast dissolving tablets of cinnarizine by direct compression method. Micro crystalline cellulose (MCC) as diluent and super disintegrants, such as Crospovidone (CP), Cinnarizine(drug), Magnesium Stearate,Talc,Mannitol and croscarmellose Sodium were used. Fast dissolving tablets disintegrates or dissolves rapidly within few seconds due to maximized pore structure in the formulation or by the action of superdisintegrants. Infrared (IR) spectroscopy was performed to identify the physicochemical interaction between drug and polymer. IR spectroscopy showed that

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6

E., Sathish Reddy Meesala. Srinivasa Rao and Mohammed Ibrahim. "FORMULATION AND IN VITRO, IN VIVO EVALUATION OF CEFADROXIL CONTROLLED GASTRORETENTIVE DRUG DELIVERY SYSTEM." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2139–50. https://doi.org/10.5281/zenodo.836461.

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Introduction: Cefadroxil is a first-generation cephalosporin and is very effective against Gram positive and Gram negative infections. Cefadroxil is an antibiotic agent which has high absorption in the upper part of the gastrointestinal tract (GIT). Conventional Cefadroxil tablets produce rapid and relatively high peak blood level and require frequent administration to keep the plasma drug level at an effective range. The present study was carried out with an objective of preparation and in vivo evaluation of floating tablets of using Cefadroxil as a model drug using Eudragit polymers to impro

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7

Simran, Tanwar, Tikariya Komal, and Sharma Vimukta. "Formulation and Evaluation of Sustained Release Matrix Tablet of Nimesulide Using Pomegranate Peel and Acacia." International Journal of Pharmaceutical Sciences and Medicine 7, no. 7 (2022): 11–24. http://dx.doi.org/10.47760/ijpsm.2022.v07i07.002.

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The main objective of the study is the formulation and evaluation of sustained release matrix tablet of Nimesulide using pomegranate peel and acacia as natural polymer. The preformulation study of Nimesulide was conducted and λmax was found at 300 nm. The sustained release matrix tablet was prepared using Pomegranate peel as Release rate retardant, Acacia as polymer, Polyvinylpyrrolidone K30 as Binder, Isopropyl alcohol as Granulation solution, Micro Crystalline Cellulose as Diluent, Magnesium stearate as Lubricant and Talc as Glidant. Several formulations were prepared by taking different dru

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8

Li, Yu, Xiangwen Kong, and Fan Hu. "Crystal Transition and Drug-excipient Compatibility of Clarithromycin in Sustained Release Tablets." Current Pharmaceutical Analysis 16, no. 7 (2020): 950–59. http://dx.doi.org/10.2174/1573412915666190328234326.

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Background: Clarithromycin is widely used for infections of helicobacter pylori. Clarithromycin belongs to polymorphic drug. Crystalline state changes of clarithromycin in sustained release tablets were found. Objective: The aim of this study was to find the influential factor of the crystal transition of clarithromycin in preparation process of sustained-release tablets and to investigate the possible interactions between the clarithromycin and pharmaceutical excipients. Methods and Results: The crystal transition of active pharmaceuticals ingredients from form II to form I in portion in clar

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9

Le, Minh-Quan, Khuong-Nhi Cao-Nguyen, Kieu-Trinh Nguyen-Tran, Van-Ha Nguyen, and Hau Le. "Influence of formulation and punch properties on sticking in the tableting process." MedPharmRes 9, no. 1 (2025): 121–33. https://doi.org/10.32895/ump.mpr.9.1.11.

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Punch sticking is a common phenomenon in tablet manufacturing, often leading to tablet defects and compromise product quality. A thorough understanding of the sticking mechanism is essential to optimize the tablet production process. The aim of this study was to investigate the influence of formulations and punch properties on sticking. Seven model active pharmaceutical ingredients (APIs) (i.e., ibuprofen, aspirin, paracetamol, metronidazole, diltiazem, diclofenac, and cefuroxime) with various melting points and particle sizes were used to evaluate their propensity for sticking. The APIs stuck

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10

Salazar-Barrantes, Karen Andrea, Ariadna Abdala-Saiz, José Roberto Vega-Baudrit, Mirtha Navarro-Hoyos, and Andrea Mariela Araya-Sibaja. "Formulation and evaluation of atorvastatin calcium trihydrate Form I tablets." PLOS ONE 20, no. 2 (2025): e0317407. https://doi.org/10.1371/journal.pone.0317407.

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Solid forms transformations and new crystal structures of an active pharmaceutical ingredient (API) can occur due to various manufacturing process conditions, especially if the drug substance is formulated as a hydrate. The conversion between hydrate and anhydrate forms caused by changes in temperature and humidity must be evaluated because of the risk of dehydration and phase transitions during the manufacturing process. Differences in physicochemical, mechanical, and rheological properties have been observed between solid forms of the same API that can cause manufacturing and product-related

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