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Journal articles on the topic 'Mahidol University Mycobacterium tuberculosis'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

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1

Widaningsih, Yuyun, Ismawati Amin, Nurhayana Sennang, Uleng Bahrun, and Mansyur Arif. "MYCOBACTERIUM TUBERCULOSIS DAN PCR." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 18, no. 3 (2016): 179. http://dx.doi.org/10.24293/ijcpml.v18i3.756.

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TB’s coinfection in HIV and AIDS is on the increase together with the high mortality rate. The disseminated TB infection (in blood) of HIV and AIDS patients in Africa (2005) is about 10−25%. The aim of this study was to identify M.tb disseminated infection in HIV and AIDS patients. In this study was done in six HIV and AIDS patients suffering from suspected TB co infection. The sputum was tested using Fast Acid Bacilli and culture (using LJ and MGIT media) and DST. The identification of M.tb in blood used PCR with IS6110 primer (123 bp). The study was done at Dr. Wahidin Sudirohusodo Hospital,

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Kenedyanti, Evin, and Lilis Sulistyorini. "Analysis of Mycobacterium tuberculosis and Physical Condition of The House with Incidence Pulmonary Tuberculosis." Jurnal Berkala Epidemiologi 5, no. 2 (2017): 152. http://dx.doi.org/10.20473/jbe.v5i22017.152-162.

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Diseases that can be caused by environmental factors one of which is tuberculosis (TB). TB is an infectious disease that most often affects the lung tissue by Mycobacterium tuberculosis. Based on the observation of the condition of the settlement in the district Mulyorejo very crowded and poor sanitation, it may result in environmentally based disease is pulmonary tuberculosis (TB). This study was an observational study, the design of the study is a case-control study. Analysis of the data used are seeing the value OR. The sample was taken by purposive sampling with a sample size of 5 houses p

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Jaleta, Kefyalew N., Mucheye Gizachew, Baye Gelaw, Habtie Tesfa, Alem Getaneh, and Belete Biadgo. "Rifampicin-resistant Mycobacterium tuberculosis among tuberculosis-presumptive cases at University of Gondar Hospital, northwest Ethiopia." Infection and Drug Resistance Volume 10 (June 2017): 185–92. http://dx.doi.org/10.2147/idr.s135935.

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4

Wolde, Deneke, Mulualem Tadesse, Kedir Abdella, Gemeda Abebe, and Solomon Ali. "Tuberculosis among Jimma University Undergraduate Students: First Insight about the Burden of Tuberculosis in Ethiopia Universities—Cross-Sectional Study." International Journal of Bacteriology 2017 (October 24, 2017): 1–6. http://dx.doi.org/10.1155/2017/9840670.

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Background. Ethiopian universities are facilities where students live in relative overcrowding condition. This might favor the chance of tuberculosis transmission among students. This study was done to determine the magnitude and associated factors of tuberculosis among Jimma University students. Methods. A cross-sectional study was done from February 2015 to July 2015. Hundred twenty-nine consented participants were interviewed using structured questionnaire. Biological specimens were collected and cultured on Mycobacterium Growth Indicator Tube. Mycobacterium tuberculosis complex verificatio

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Oliveira, Sandra Maria do Valle Leone de, Michael Robin Honner, Anamaria Mello Miranda Paniago, Eliana Setti Albuquerque Aguiar, and Rivaldo Venâncio da Cunha. "Prevalence of mycobacterium tuberculosis among professionals in a university hospital, Mato Grosso do Sul, 2004." Revista Latino-Americana de Enfermagem 15, no. 6 (2007): 1120–24. http://dx.doi.org/10.1590/s0104-11692007000600010.

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Several studies have demonstrated an elevated prevalence amongst professionals of mycobacterium tuberculosis, both in the rate of infections and illness. This study was carried out in a School Hospital in Campo Grande, MS, Brazil, aiming to establish the prevalence of infection with Mycobacterium tuberculosis. The results of the analysis of 194 subjects showed an overall positivity for the tuberculin test of 38.7%. There was a correlation with smoking (p=0.01, RP=1. 72 (1.20-2.45- Yates's correction). The conclusion is that the establishment of a program of tuberculin screening jointly with th

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Kim, Woo Jin, Jae Joon Yim, Jae Ho Lee, et al. "Restriction Fragment Length Polymorphism of Mycobacterium tuberculosis in a University Hospital in Seoul." Tuberculosis and Respiratory Diseases 48, no. 3 (2000): 308. http://dx.doi.org/10.4046/trd.2000.48.3.308.

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Daniel, Olusoji J., Janet Olufisayo Bamidele, John Kolawole Sodeinde, Adeola Adebayo Ekundayo, and Adekunle Albert Salako. "Rifampicin resistance among patients with Tuberculosis at the Olabisi Onabanjo University Teaching Hospital, Sagamu." Annals of Health Research 4, no. 1 (2018): 53–59. http://dx.doi.org/10.30442/ahr.0401-1-07.

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Background: Tuberculosis (TB) is a major public health problem in Nigeria. The emergence of multidrug-resistant Tuberculosis poses a threat to global Tuberculosis control and if not effectively addressed, may wipe out the achievements of previous efforts in controlling Tuberculosis. Objectives: To determine the prevalence and factors associated with rifampicin resistance amongpatients receiving care for TB at the OlabisiOnabanjo University Teaching Hospital, Sagamu. Methods: A retrospective study of presumptive Tuberculosis cases managed between January 2013 and December 2016 at the Directly O

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Maciel, Mônica Maria Moreira Delgado, Maria das Graças Ceccato, Wânia da Silva Carvalho, Pedro Daibert de Navarro, Kátia de Paula Farah, and Silvana Spindola de Miranda. "Prevalence of latent Mycobacterium tuberculosis infection in renal transplant recipients." Jornal Brasileiro de Pneumologia 44, no. 6 (2018): 461–68. http://dx.doi.org/10.1590/s1806-37562017000000367.

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ABSTRACT Objective: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemographic, behavioral, and clinical associations with positive tuberculin skin test (TST) results. Methods: This was a cross-sectional study of patients aged ≥ 18 years who underwent renal transplantation at the Renal Transplant Center of the Federal University of Minas Gerais Hospital das Clínicas, located in the city of Belo Horizonte, Brazil. We included renal transplant recipients who underwent the TST between January 2011 and July 2013. I

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Zaki, Maysaa El-Sayed, and Samir Abou-El Hassan. "Clinical Evaluation of Gen-Probe's Amplified Mycobacterium Tuberculosis Direct Test for Rapid Diagnosis of Mycobacterium tuberculosis in Egyptian Children at Risk for Infection." Archives of Pathology & Laboratory Medicine 132, no. 2 (2008): 244–47. http://dx.doi.org/10.5858/2008-132-244-ceogam.

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Abstract Context.—Diagnostic detection of tuberculosis (TB) has improved considerably. Available, standardized, nucleic acid–based amplification techniques have been shown to yield reliable results within 4 to 7 hours of sample processing. Objective.—To study the diagnostic performance of Gen-Probe's technique for direct detection of Mycobacterium tuberculosis in comparison with BACTEC 460 TB culture for both positive and negative Ziehl-Neelsen smears in Egyptian children at risk for TB infection. Design.—We prospectively evaluated 50 children from families with a positive history of TB. All p

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Ghaleb, Khaled Ismail, Magdy Mohamed Afifi, and Mohamed Mohamed El Gohary. "ASSESSMENT OF DIAGNOSTIC TECHNIQUES OF URINARY TUBERCULOSIS." Mediterranean Journal of Hematology and Infectious Diseases 5, no. 1 (2013): e2013034. http://dx.doi.org/10.4084/mjhid.2013.034.

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Khalid Ghaleb a,* , Magdy Afifib, Mohamad El-Gohary c aDepartment of Medical Laboratories, Faculty of Applied Medical Science, King Khalid University, Bisha 551, Saudia Arabia bDepartment of Botany and Microbiology, Faculty of Science, Al-Azhar University, Assuit 71524, Egypt cDepartment of Internal Medicine, Faculty of Medicine, Al-Azhar University, Assuit, Egypt The corresponding author e-mail: kh_ghaleb4@hotmail.com Current Tel: 00966595388496 Saudia, 00201119338055 Egypt The place of the study worked : Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Assuit 7

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Aharmim, Mohamed, Khalid Bouti, Mouna Soualhi, et al. "Pediatric Tuberculosis at Moulay Youssef University Hopsital – Morocco." International Journal of Medicine and Surgery 1, no. 1 (2014): 17–22. http://dx.doi.org/10.15342/ijms.v1i1.4.

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Background: There are few studies on presentations, treatment and outcomes of pediatric tuberculosis in Morocco. This study aimed to describe clinico-epidemiological profiles, laboratory findings, treatment and outcomes of pediatric tuberculosis (TB) in a tertiary care hospital in Morocco. Materials and Methods: This is a prospective, descriptive study undertaken in children diagnosed with TB between June 2011 and May 2012. Clinico-pidemiologicalprofiles, laboratory findings, treatment and outcome of patients was recorded. Statistical significance of category variables was evaluated. Analysis

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Gebrezgabiher, Gebremedhin, Gebremedhin Romha, and Gobena Ameni. "Spoligotyping of Mycobacterium tuberculosis isolates from tuberculosis diagnosed patients at Dilla University Referral Hospital and other private clinics, Southern Ethiopia." Asian Pacific Journal of Tropical Disease 5, no. 4 (2015): 329–33. http://dx.doi.org/10.1016/s2222-1808(14)60792-1.

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Fanosie, Alemu, Baye Gelaw, Belay Tessema, Wogahta Tesfay, Aschalew Admasu, and Gashaw Yitayew. "Mycobacterium tuberculosis Complex and HIV Co-Infection among Extrapulmonary Tuberculosis Suspected Cases at the University of Gondar Hospital, Northwestern Ethiopia." PLOS ONE 11, no. 3 (2016): e0150646. http://dx.doi.org/10.1371/journal.pone.0150646.

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14

Ramaswamy, Srinivas V., Shu-Jun Dou, Adrian Rendon, Zhenhua Yang, M. Donald Cave, and Edward A. Graviss. "Genotypic analysis of multidrug-resistant Mycobacterium tuberculosis isolates from Monterrey, Mexico." Journal of Medical Microbiology 53, no. 2 (2004): 107–13. http://dx.doi.org/10.1099/jmm.0.05343-0.

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Thirty-seven multidrug-resistant and 13 pan-susceptible isolates of Mycobacterium tuberculosis were analysed for the diversity of genotypes associated with known drug-resistance mechanisms. The isolates were obtained from patients attending a university tuberculosis clinic in Monterrey, Mexico. A total of 25 IS6110-RFLP patterns were obtained from the multidrug-resistant tuberculosis (MDR-TB) isolates. Approximately 65 % of the MDR-TB isolates were attributed to secondary resistance. Different drug-susceptibility patterns were seen with the clustered isolates. The percentage of isolates resist

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Abror, Yogi Khoirul, Evy Diah Woelansari, and Suhariyadi Suhariyadi. "Immunomodulator of Ethanol Extracts of The Leaves Azadirachta indica Against Macrophage Peritoneal Cell in Mice Induced The Vaccine BCG." Jurnal Teknologi Laboratorium 7, no. 1 (2018): 8. http://dx.doi.org/10.29238/teknolabjournal.v7i1.110.

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This research was conducted to determine the immunomodulatory effect of ethanol extract of neem leaves (Azadirachta indica) to the number of peritoneal macrophages in mice wich induced by BCG vaccine. Bacillus Calmette-Guerin (BCG) vaccine contained an attenuated Mycobacterium bovis. Mycobacterium bovis belongs to the Mycobacterium Tuberculosis Complex (MTC) group that has a similar phenotype characteristic with Mycobacterium tuberculosis and similar clinical manifestations of tuberculosis.The type of the research that used in this study is laboratory experimental research with Post Test Desig

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16

Rahajoe, Nastiti N., Darmawan B. Setyanto, Muhammad Rhum, and Tetty A. Usman. "Conjunctival Mycobacteriosis." Paediatrica Indonesiana 33, no. 7-8 (2019): 182–90. http://dx.doi.org/10.14238/pi33.7-8.1993.182-90.

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A 6 1/2- year old Indonesian girl with 30 kg of body weight was consulted to the Department of Child Health, Cipto Mangunkusumo Hospital - Medical School University of Indonesia , Jakarta, for eye, surgery tolerance. At 3 1/2 years old, she came for the first time with a granulomatous tumor on her left eye. Excision was done, and histopathologic examination revealed granulation tissue corresponding to tuberculosis. The patient was referred to the Department of Child Health for further exploration. Sensitin test was positive for Mycobacterium intracellulare, not for Mycobacterium tuberculosis.

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Kiady, Ravahatra, Rakotondrabe Iantsotiana Davidson, Rasoafaranirina Marie Odette, Tiaray Harison Michel, Nandimbiniaina Anjara, and Rakotoson Joëlson Lovaniaina. "Profil De Résistance Des Mycobabcterium Tuberculosis Des Malades En Retraitement Dans La Région De Haute Matsiatra, Madagascar." European Scientific Journal, ESJ 13, no. 18 (2017): 465. http://dx.doi.org/10.19044/esj.2017.v13n18p465.

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Introduction: Relapse, failure and defaulted treatment are a risk factor for Mycobacterium tuberculosis resistance to anti-tuberculosis. The objective of our study is to determine the resistance profile of Mycobacterium tuberculosis of patients in retreatment at the Haute Matriatra area. Method: This is a retrospective, descriptive study carried out on the basis of the data contained in the register of the Haute Matsiatra Regional Tuberculosis Laboratory of the University Hospital of Fianarantsoa, from May 2014 to December 2016 (31 months). We included patients with retreatment in the study. R

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Welch, Ryan J., Kathleen M. Lawless, and Christine M. Litwin. "Antituberculosis IgG Antibodies as a Marker of Active Mycobacterium tuberculosis Disease." Clinical and Vaccine Immunology 19, no. 4 (2012): 522–26. http://dx.doi.org/10.1128/cvi.05573-11.

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ABSTRACTAnti-Mycobacterium tuberculosisIgG antibodies may aid in the diagnosis of activeM. tuberculosisdisease. We studied whether anti-M. tuberculosisIgG antibodies are elevated in activeM. tuberculosisdisease and assessed factors contributing to false-positive and -negative results. A retrospective study of 2,150 individuals tested by the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay was conducted at the University of Utah, ARUP Laboratories, November 2008 to December 2010. All samples were tested with the InBios Active TbDetectantituberculosis (anti-TB) IgG antibody assay. Of 1,044 patients w

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Maciel, Ethel Leonor Noia, Maria Carmen Viana, Regina Célia Gomes Zeitoune, Ilce Ferreira, Geisa Fregona, and Reynaldo Dietze. "Prevalence and incidence of Mycobacterium tuberculosis infection in nursing students in Vitória, Espírito Santo." Revista da Sociedade Brasileira de Medicina Tropical 38, no. 6 (2005): 469–72. http://dx.doi.org/10.1590/s0037-86822005000600004.

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This prospective study evaluated the incidence of Mycobacterium tuberculosis infection among nursing students at the Federal University of Espírito Santo, using the purified protein derivative test. In parallel, we evaluated whether knowledge on tuberculosis transmission mechanisms had any impact on nursing students' attitudes in relation to the risk of tuberculosis infection. The incidence of tuberculin conversion was 10.5% per year (p=0.035, 95% CI = 3.63-17.43), whereas the expected conversion rate in the overall population in Brazil is 0.5% per year. These results indicate nursing students

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Tulapunt, Nattapong, Swarin Phanchan, and Vichan Peonim. "Hanging Fatalities in Central Bangkok, Thailand: A 13-Year Retrospective Study." Clinical Medicine Insights: Pathology 10 (January 1, 2017): 117955571769254. http://dx.doi.org/10.1177/1179555717692545.

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Hanging is violent asphyxial death. The objective of this study is to assess the data of hanging cases. A descriptive-retrospective study was conducted. We studied 244 hanging cases autopsied in Forensic Division, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, between January 2001 and December 2013. The study included 197 men (80.7%) and 47 women (19.2%). Their age ranged from 14 to 93 years. Most of these cases were incomplete hanging (83.6%). Features of hanging victims, such as tongue protrusion; congestion of face; petechial hemorr

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Bwalya, Precious, Tomoyuki Yamaguchi, Eddie Samuneti Solo, et al. "Characterization of Mutations Associated with Streptomycin Resistance in Multidrug-Resistant Mycobacterium tuberculosis in Zambia." Antibiotics 10, no. 10 (2021): 1169. http://dx.doi.org/10.3390/antibiotics10101169.

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Streptomycin (STR) is recommended for the management of multidrug-resistant tuberculosis (MDR-TB). Streptomycin resistance-conferring mutation types and frequency are shown to be influenced by genotypes of circulating strains in a population. This study aimed to characterize the mutations in MDR-TB isolates and examine their relationship with the genotypes in Zambia. A total of 138 MDR-TB isolates stored at the University Teaching Hospital Tuberculosis Reference Laboratory in Zambia were analyzed using spoligotyping and sequencing of STR resistance-associated genes. Streptomycin resistance was

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Ouassa, T., M. S. N’Guessan-Kacou, and K. A. Kouakou. "Non-tuberculous mycobacteria isolated from patients with suspected tuberculosis in Abidjan, Ivory Coast." African Journal of Clinical and Experimental Microbiology 22, no. 2 (2021): 304–9. http://dx.doi.org/10.4314/ajcem.v22i2.26.

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Background: Apart from tuberculosis caused by Mycobacterium tuberculosis complex (MTBc) species, there are many other mycobacterial infections due to nontuberculous mycobacteria (NTM). These are rarely identified in many low resource settings in Africa because of the lack of accurate identification methods. The aim of the study is to identify NTM species involved in respiratory infections in Abidjan, Ivory Coast.Methodology: Isolates routinely identified as NTM by the detection of MPT64 antigen between 2015 and 2018 at the Centre for Diagnosis and Research on AIDS and other Infectious Diseases

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Chen, Guangliang. "INCREASED RISK OF LYMPHOMA IN MEN INFECTED WITH TUBERCULOSIS." Mediterranean Journal of Hematology and Infectious Diseases 13, no. 1 (2021): e2021053. http://dx.doi.org/10.4084/mjhid.2021.053.

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Purpose: To identify factors associated with lymphoma in patients with anterior Mycobacterium tuberculosis (TB). Methods: A retrospective case-control analysis was performed in a highly tuberculosis-endemic area. TB-infected patients were retrospectively identified when a history of TB exists before the diagnosis of lymphoma. Inpatients with lymphoma (n=1,057) and benign tumors (n=12,916) were consecutively enrolled at Xinjiang Medical University Cancer Hospital between January 2016 and December 2019. Results: The proportion of TB in patients with lymphoma (n=148, 14.0%) was signif

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Schafbuch, Ryan, Stacy Tinkler, Chee Kin Lim, Rebecca Wolking, and José Ramos-Vara. "Disseminated mycobacteriosis caused by Mycobacterium kansasii in a pot-bellied pig." Journal of Veterinary Diagnostic Investigation 30, no. 4 (2018): 646–50. http://dx.doi.org/10.1177/1040638718780189.

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A 1.5-y-old spayed female Juliana pot-bellied pig was presented to the Purdue University Veterinary Teaching Hospital with a history of wasting and anorexia. Enlarged and partially mineralized lymph nodes were identified on radiographs and computed tomography scan. Generalized lymphadenomegaly and disseminated nodules in the lungs, liver, spleen, and kidneys were identified on postmortem examination. Histologic examination revealed caseonecrotic granulomas with numerous intracellular, acid-fast bacilli. Mycobacterium kansasii type II was identified as the etiologic agent by PCR amplification u

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Wada, Takayuki, Shinji Maeda, Atsushi Hase, and Kazuo Kobayashi. "Evaluation of variable numbers of tandem repeat as molecular epidemiological markers of Mycobacterium tuberculosis in Japan." Journal of Medical Microbiology 56, no. 8 (2007): 1052–57. http://dx.doi.org/10.1099/jmm.0.46990-0.

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Using 243 Mycobacterium tuberculosis isolates obtained in 2001 in Osaka City, Japan, the discriminatory power of variable numbers of tandem repeats (VNTRs) of 12 standard mycobacterial interspersed repetitive units (MIRUs) was assessed. The biggest cluster defined by MIRU-VNTRs consisted of 57 (23.5 %) isolates and they belonged to the Beijing family based on spoligotyping. When additional VNTR loci were included in the MIRU-VNTR analysis, the 57 originally clustered strains were further differentiated by the addition of Queen's University Belfast (QUB)-VNTRs, but not exact tandem repeat-VNTR.

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Hansen, Kamille Carstens, Søren Jensen-Fangel, and Bo Langhoff Hønge. "Contribution to differential diagnosis of sarcoidosis and disseminated tuberculosis." BMJ Case Reports 12, no. 11 (2019): e230652. http://dx.doi.org/10.1136/bcr-2019-230652.

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A previously healthy 54-year-old ethnically Danish man was referred to the Department of Infectious Diseases at Aarhus University Hospital after an unexpected detection of Mycobacterium tuberculosis DNA in his lungs. Further examination revealed widespread dissemination of the tuberculosis (TB) to brain, mastoid, urinary and gastrointestinal tract. Thirteen months earlier, the patient was orchiectomised due to recurring inflammation of the right testicle. Three and a half months prior to admission to our department the patient started immunosuppressive therapy with steroids due to radiological

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Musoni, Emile, Alphonse Niyodusenga, Sylvain Iradukunda, and Consolee Uwamahoro. "Contribution of fine needle aspiration and auramine tests in diagnosis of Tuberculosis lymphadenitis at Kigali University Teaching Hospital (CHUK), Rwanda." Rwanda Journal of Medicine and Health Sciences 3, no. 1 (2020): 86–92. http://dx.doi.org/10.4314/rjmhs.v3i1.10.

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Background Tuberculosis (TB) is an infection caused by Mycobacterium tuberculosis. Tuberculosis affects mainly the lungs but other organs of the body are involved. TB lymphadenitis is most common in extrapulmonary TB. Lymphadenitis is the infection or inflammation of the lymph nodes which are essential in immune response of the body. Objective To evaluate the contribution of fine needle aspiration (FNA) and auramine tests in the diagnosis of TB lymphadenitis. Methods Smears from lymph node aspirates were prepared. Air-dried smears were stained by auramine staining

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Ukaegbu, Chisom, Agatha Ani, and Agwu Nnachi. "Molecular Detection of Mycobacterium tuberculosis Complex by GenoType®MTBDRplus from Patients Attending Bingham University Teaching Hospital, Jos, Nigeria." British Journal of Pharmaceutical Research 9, no. 6 (2016): 1–11. http://dx.doi.org/10.9734/bjpr/2016/22991.

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Paschoal, Gabriela Dos Santos, Gabriela Santos de Souza, Mariele Pereira, and Luisa Patrícia Fogarolli de Carvalho. "Tuberculose: os futuros profissionais de saúde são preparados para o atendimento adequado do paciente?" International Journal of Health Education 2, no. 1 (2018): 73. http://dx.doi.org/10.17267/2594-7907ijhe.v2i1.2045.

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Introduction: According to the World Health Organization (WHO), one third of the world’s population is infected with Mycobacterium tuberculosis(1). The literature shows that the multiprofessional team responsible for managing tuberculosis is not able to dealing with re-emergence of the disease, in addition acting in non-integral and humanized way. Objective: To check if university students that will be inserted in primary care are able to identify and manage patients with tuberculosis. Methods and materials: Semi-structured questionnaires were applied to students of the last periods of health

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Ch, Muhammad Khalid, Muhammad Saqib Saeed, Rizwan Iqbal, and Akhtar Ali. "Gene Xpert MTB / RIF – Diagnostic Role in Tuberculous Pleurisy." Annals of King Edward Medical University 22, no. 1 (2016): 78. http://dx.doi.org/10.21649/akemu.v22i1.803.

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<p><strong>Abstract</strong></p><p><strong>Background: </strong>Tuberculous pleurisy is a common extrapulmonary manifestation and is second to tuberculous lymphadenitis. Due to its paucibacillary in origin, its diagnosis is a challenge. Furthermore, it is also complicated by the emergence of MDR. Gene Xpert MTB/RIF is a new rapid promising innovation for the detection of mycobacterium tuberculosis and its resistance to Rifampicin, giving result within two hours.</p><p><strong>Objective: </strong>To evaluate the diagnostic role o

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Lian-HuatTan, Adeeba Kamarulzaman, Chong-Kin Iiam, and Toong-Chow Lee. "Tuberculin Skin Testing Among Healthcare Workers in the University of Malaya Medical Centre, Kuala Lumpur, Malaysia." Infection Control & Hospital Epidemiology 23, no. 10 (2002): 584–90. http://dx.doi.org/10.1086/501975.

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Objectives:To determine the occupational risk of Mycobacterium tuberculosis infection among healthcare workers (HCWs) and to examine the utility of tuberculin skin testing in a developing country with a high prevalence of bacille Calmette-Guerin vaccination.Design:Tuberculin skin test (TST) survey.Setting:A tertiary-care referral center and a teaching hospital in Kuala Lumpur, Malaysia.Participants:HCWs from medical, surgical, and orthopedic wards.Intervention:Tuberculin purified protein derivative RT-23 (State Serum Institute, Copenhagen, Denmark) was used for the TST (Mantoux method).Results

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Mekonnen, Abiyu, Matthias Merker, Jeffrey M. Collins, et al. "Molecular epidemiology and drug resistance patterns of Mycobacterium tuberculosis complex isolates from university students and the local community in Eastern Ethiopia." PLOS ONE 13, no. 9 (2018): e0198054. http://dx.doi.org/10.1371/journal.pone.0198054.

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Januškevica, Inga, Baiba Rozentāle, Elvīra Hagina та ін. "Role of Interferon-Gamma (Ifn-γ) in Immune Response Regulation in Hiv-1 and Hiv-1 + Mycobacterium Tuberculosis (Tb) Infected Patients / Interferona-gamma (Ifn-γ) Loma Imūnās Atbildes Regulēšanā Pacientiem Ar HIV-1 un HIV-1 + mycobacterium Tuberculosis". Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 70, № 4 (2016): 211–14. http://dx.doi.org/10.1515/prolas-2016-0033.

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Abstract The aim of this research was to investigate the role of IFN-γ in interaction between IL-10, IL-18, IL-1b, CD4 cell counts and HIV-1 RNA viral load in the development of HIV-1 in patients co-infected with Mycobacterium tuberculosis (TB). The study was conducted by Rīga East Clinical University Hospital with data from the HIV-1 register, in collaboration with the RSU Joint Laboratory of Clinical Immunology and Immunogenetics. 200 HIV-1 infected patients and 184 HIV-1 with TB co-infection patients divided in four groups were included in the study. IFN-γ, IL-10, IL-18, IL-1b levels were m

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Sodja, E., N. Toplak, S. Koren, M. Kovač, S. Truden, and M. Žolni-Dovč. "Next-generation sequencing of drug resistant Mycobacterium tuberculosis clinical isolates in low-incidence countries." Russian Journal of Infection and Immunity 9, no. 5-6 (2020): 773–78. http://dx.doi.org/10.15789/2220-7619-2019-5-6-773-778.

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Drug resistant tuberculosis (TB), especially multidrug (MDR) and extensively drug-resistant (XDR) TB, is still a serious problem in global TB control. Slovenia and North Macedonia are low-incidence countries with TB incidence rates of 5.4 and 10.4 in 2017, respectively. In both countries, the percentage of drug resistant TB is very low with sporadic cases of MDR-TB. However, global burden of drug-resistant TB continues to increase imposing huge impact on public health systems and strongly stimulating the detection of gene variants related with drug resistance in TB. Next-generation sequencing

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Hadebe, Sabelo, Melissa Chengalroyen, Reto Guler, et al. "Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town." Gates Open Research 3 (June 12, 2019): 1491. http://dx.doi.org/10.12688/gatesopenres.13035.1.

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Tuberculosis, caused by the highly infectious Mycobacterium tuberculosis, remains a leading cause of death worldwide, with an estimated 1.6 million associated deaths reported in 2017. In South Africa, an estimated 322,000 people were infected with TB in 2017, and a quarter of them lost their lives due to the disease. Bacille Calmette-Guérin remains the only effective vaccine against disseminated TB, but its inability to confer complete protection against pulmonary TB in adolescents and adults calls for an urgent need to develop new and better vaccines. There is also a need to identify markers

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Meacham, Holly, Takaaki Kobayashi, Mohammed Alsuhaibani, et al. "Tuberculosis Exposure and Conversion Rates Can Guide Deimplementation of Annual Tuberculosis Screening." Infection Control & Hospital Epidemiology 41, S1 (2020): s419. http://dx.doi.org/10.1017/ice.2020.1075.

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Background: The CDC recently updated recommendations on tuberculosis (TB) screening in healthcare facilities, suggesting the discontinuation of annual TB screening. However, hospitals may opt to continue based on their local TB epidemiology. We assessed TB infection control parameters in our facility to guide the implementation of the new CDC recommendations. Methods:We retrieved data for patients with an International Classification of Disease, Tenth Revision (ICD-10) code for TB treated at the University of Iowa Hospitals and Clinics during 2016–2019. We supplemented our search with microbio

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Silva, Fernanda Schaefer Borges da, Aline Lemes Castilho, Flaviane Granero Maltempe, et al. "Use of the Ogawa-Kudoh method to isolate mycobacteria in a tuberculosis reference laboratory in northwestern Paraná, Brazil." Brazilian Journal of Pharmaceutical Sciences 49, no. 3 (2013): 567–70. http://dx.doi.org/10.1590/s1984-82502013000300018.

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Culturing is the gold standard method for confirming a diagnosis of tuberculosis (TB). The Brazilian Ministry of Health recently proposed the use of the Ogawa-Kudoh method for sputa cultures to detect Mycobacterium tuberculosis. The aim of the present study was to evaluate 8 years of using the Ogawa-Kudoh method in a TB reference laboratory in northwestern Paraná, Brazil. The present study consisted of a retrospective analysis of sputa cultures records for the detection of mycobacteria using the Ogawa-Kudoh method in the Laboratory of Medical Bacteriology, Laboratory of Teaching and Research i

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Hadebe, Sabelo, Melissa Chengalroyen, Reto Guler, et al. "Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town." Gates Open Research 3 (November 12, 2019): 1491. http://dx.doi.org/10.12688/gatesopenres.13035.3.

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Tuberculosis (TB), caused by the highly infectious Mycobacterium tuberculosis, remains a leading cause of death worldwide, with an estimated 1.6 million associated deaths reported in 2017. In South Africa, an estimated 322,000 (range 230,000-428,000) people were infected with TB in 2017, and a quarter of them lost their lives due to the disease. Bacille Calmette-Guérin (BCG) remains the only effective vaccine against disseminated TB, but its inability to confer complete protection against pulmonary TB in adolescents and adults calls for an urgent need to develop new and better vaccines. There

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Hadebe, Sabelo, Melissa Chengalroyen, Reto Guler, et al. "Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town." Gates Open Research 3 (May 28, 2020): 1491. http://dx.doi.org/10.12688/gatesopenres.13035.4.

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Tuberculosis (TB), caused by the highly infectious Mycobacterium tuberculosis, remains a leading cause of death worldwide, with an estimated 1.6 million associated deaths reported in 2017. In South Africa, an estimated 322,000 (range 230,000-428,000) people were infected with TB in 2017, and a quarter of them lost their lives due to the disease. Bacille Calmette-Guérin (BCG) remains the only effective vaccine against disseminated TB, but its inability to confer complete protection against pulmonary TB in adolescents and adults calls for an urgent need to develop new and better vaccines. There

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Ani, Agatha, Silvanis Okpe, Maxwell Akambi, et al. "Comparison of a DNA based PCR method with conventional methods for the detection of M. tuberculosis in Jos, Nigeria." Journal of Infection in Developing Countries 3, no. 06 (2009): 470–75. http://dx.doi.org/10.3855/jidc.420.

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Background: To achieve early diagnosis and effective treatment of pulmonary tuberculosis, simple and sensitive methods that enhance the detection of Mycobacterium tuberculosis (M. tuberculosis) from clinical specimens are needed. This study compared the effectiveness and suitability of an insertion sequence (IS 6110) based polymerase chain reaction (PCR) assay with conventional methods for the detection of M. tuberculosis from clinical specimens in a resource-limited setting. Methods: Sputa from 101 HIV-positive patients and 40 clinical specimens (sputa, gastic wash out, ascitic fluid, pleural

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Salmah, Shelly, and Ariani Said Culla. "IDENTIFICATION OF Mycobacterium tuberculosis BY POLYMERASE CHAIN REACTION (PCR) TEST AND ITS RELATIONSHIP TO MGG STAINING OF PLEURAL FLUID IN PATIENTS WITH SUSPECTED TUBERCULOUS PLEURAL EFFUSION." Nusantara Medical Science Journal 3, no. 2 (2018): 18. http://dx.doi.org/10.20956/nmsj.v3i2.5778.

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Pleural effusion is a condition characterized by the accumulation of excessive pleural fluid in pleural cavity as a result of transudation and exudation. The most commonly reported cause of exudative pleural effusion is Mycobaterium tuberculosis. This study was aimed to identify Mycobacterium tuberculosis in pleural fluid through PCR test and to examine the relationship between PCR test and MGG staining of pleural fluid in patients with suspected tuberculous pleural effusion, which was performed in Clinical Pathological Laboratory Installation of dr. Wahidin Sudirohusodo hospital in Makassar a

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Corvino, Anna Rita, Maria Grazia Lourdes Monaco, Elpidio Maria Garzillo, et al. "Tuberculosis Infection Screening in 5468 Italian Healthcare Students: Investigation of a Borderline Zone Value for the QFT-Test." International Journal of Environmental Research and Public Health 17, no. 18 (2020): 6773. http://dx.doi.org/10.3390/ijerph17186773.

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Healthcare workers are at an increased risk of contracting Mycobacterium tuberculosis infection. Tuberculin skin test (TST) and interferon gamma release assay (IGRA) represent the available tests most used for the diagnosis of latent tuberculosis infection (LTBI). Different borderline zones have been proposed for defining conversions and reversions to improve the interpretation of the IGRA test results as part of serial testing. From 2012 to 2017, 5468 health students of an Italian University Hospital were screened for tuberculosis infection through the execution of the TST and, in case of pos

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Cailleaux-Cezar, Michelle, Carla Loredo, José Roberto Lapa e. Silva, and Marcus Barreto Conde. "Impact of smoking on sputum culture conversion and pulmonary tuberculosis treatment outcomes in Brazil: a retrospective cohort study." Jornal Brasileiro de Pneumologia 44, no. 2 (2018): 99–105. http://dx.doi.org/10.1590/s1806-37562017000000161.

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ABSTRACT Objective: To evaluate the impact of smoking on pulmonary tuberculosis (PTB) treatment outcomes and the two-month conversion rates for Mycobacterium tuberculosis sputum cultures among patients with culture-confirmed PTB in an area with a moderate incidence of tuberculosis in Brazil. Methods: This was a retrospective cohort study of PTB patients diagnosed and treated at the Thoracic Diseases Institute of the Federal University of Rio de Janeiro between 2004 and 2012. Results: Of the 298 patients diagnosed with PTB during the study period, 174 were included in the outcome analysis: 97 (

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Pegues, Clare F., Douglas C. Johnson, David A. Pegues, Maureen Spencer, and Cyrus C. Hopkins. "Implementation and Evaluation of an Algorithm for Isolation of Patients With Suspected Pulmonary Tuberculosis." Infection Control & Hospital Epidemiology 17, no. 7 (1996): 412–18. http://dx.doi.org/10.1017/s0195941700006779.

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AbstractObjective: To implement and evaluate an algorithm designed to assist in the consistent placement of patients with suspected pulmonary tuberculosis into negative-pressure isolation rooms (NPIRs).Design: A standard algorithm was designed for the appropriate room placement of patients with suspected pulmonary tuberculosis using clinical, radiographic, and laboratory criteria and reported risk factors. A case-patient was defined as an inpatient who had at least one Mycobacterium tuberculosis culture-positive respiratory specimen from January 1, 1993, through December 31, 1994. Demographic,

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Catanzaro, Antonino, та Charles Daley. "A Summary of the Third Global Interferon-γ Release Assay Symposium". Infection Control & Hospital Epidemiology 34, № 6 (2013): 619–24. http://dx.doi.org/10.1086/670634.

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Studies over the past several decades have dramatically increased our understanding of the immune response to Mycobacterium tuberculosis infection, and advances in proteomics and genomics have led to a new class of immune-diagnostic tests, termed interferon-γ (IFN-γ) release assays (IGRAs), which appear to obviate many of the problems encountered with the tuberculin skin test (TST). Worldwide, 2 IGRAs are currently commercially available. QuantiFERON-TB Gold In-Tube (Cellestis) is a third-generation product that uses an enzyme-linked immunosorbent assay to measure IFN-γ generated in whole bloo

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Vermaak, Samantha, Helen Fletcher, and Helen McShane. "OC 8259 THE VALIDATE NETWORK: EXPLOITING SYNERGIES BETWEEN COMPLEX INTRACELLULAR NEGLECTED PATHOGENS TO EXPEDITE VACCINE R&D FOR TUBERCULOSIS, LEISHMANIASIS, LEPROSY AND MELIOIDOSIS." BMJ Global Health 4, Suppl 3 (2019): A3.1—A3. http://dx.doi.org/10.1136/bmjgh-2019-edc.5.

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BackgroundThe VALIDATE ‘VAccine deveLopment for complex Intracellular neglecteD pAThogEns’ Network is a Global Challenges Research Fund (GCRF) Network, funded by the UK MRC and BBSRC and led by the University of Oxford and the London School of Hygiene and Tropical Medicine. It aims to accelerate vaccine development for four intracellular pathogens, Mycobacterium tuberculosis, Leishmania spp, Mycobacterium leprae and Burkholderia pseudomallei, by creating a network of scientists from around the world in an interactive community, sharing information, learning from synergies and differences, and

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Zakria, Muhammad, and Muhammad Ashraf. "FACTORS AFFECTING ON OBESITY AND UNDERWEIGHT WITH OUTCOME AMONG PEOPLE LIVING IN THE VICINITY OF MARZIPURA, FAISALABAD." Professional Medical Journal 21, no. 05 (2018): 1063–69. http://dx.doi.org/10.29309/tpmj/2014.21.05.2563.

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… Due to transformation in nutritional status, along with epidemiological and sociodemographic changes in developing countries like Pakistan, obesity and underweight coexistin our community. Date about coexistence of obesity (body mass index, BMI ≥ 30kg/m2) andunderweight (BMI ≥ 18.5 kg/m2) and related factors are lacking in this region of our province.This study will help us to relate different sociodemographic factors with obesity and underweight.Objective: To know the prevalence of obesity and underweight by body mass index (BMI) andto investigate the association of obesity and underweight

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Alian, Shahriar, Amir Dadashi, Narges Najafi, et al. "Evaluation of Tuberculin Skin Test (TST) in Medical Students in Mazandaran University of Medical Sciences, Sari, Iran." Global Journal of Health Science 9, no. 5 (2016): 274. http://dx.doi.org/10.5539/gjhs.v9n5p274.

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<p><strong>BACKGROUND: </strong>Working in health care units has been known as occupational risk factor in mycobacterium tuberculosis (TB) infection. The TB exposure rate in medical students is more than other people. In several studies significant correlation has been reported between hospital presence hours and positive PPD test prevalence. With regard to morbidity of several medical students and nursing staff due to primary tuberculosis in recent years, we decided to investigate positive tuberculin skin test (TST) prevalence in medical students and examine correlation betw

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Galal, Nermeen, Jeannette Boutros, Aisha Marsafy, et al. "MENDELIAN SUSCEPTIBILITY TO MYCOBACTERIAL DISEASE IN EGYPTIAN CHILDREN." Mediterranean Journal of Hematology and Infectious Diseases 4, no. 1 (2012): e2012033. http://dx.doi.org/10.4084/mjhid.2012.033.

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Background: Tuberculosis remains a major health problem in developing countries especially with the emergence of multidrug resistant strains. Mendelian Susceptibility to Mycobacterial Disease (MSMD) is a rare disorder with impaired immunity against mycobacterial pathogens. Reported MSMD etiologies highlight the crucial role of the Interferon gamma /Interleukin 12 (IFN-g/ IL-12) axis and the phagocyte respiratory burst axis.Purpose: Screen patients with possible presentations for MSMD.Methods: Patients with disseminated BCG infection following vaccination, atypical mycobacterial infections or r

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Sabiiti, Wilber. "United Kingdom–East and Southern Africa Partnership at the Forefront of Developing the First Ever Test that Measures Patient Tuberculosis Burden in Hours." East Africa Science 1, no. 1 (2019): 3–8. http://dx.doi.org/10.24248/easci.v1.iss1.11.

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Mycobacterium tuberculosis has caused tuberculosis (TB) in humans for at least 3 millennia, but the disease has evaded eradication efforts by all human civilisations despite promising technological advancements. The World Health Organization (WHO) has set a target of ending the TB epidemic by 2035. Going by the current rate of progress, it is estimated that it will take another 160 years to realise the WHO End TB Strategy’s target. Accelerating the eradication of TB will require effective tools for diagnosis, vaccines and medicines to treat the disease, and efficient implementation thereof. Th

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