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Journal articles on the topic 'Makromolekül'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 January 2023

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1

Braun, Dietrich. "Der lange Weg zum Makromolekül." Chemie in unserer Zeit 46, no. 5 (2012): 310–20. http://dx.doi.org/10.1002/ciuz.201200566.

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2

Klug, Aaron. "Vom Makromolekül zum biologischen Molekülverband (Nobel-Vortrag)." Angewandte Chemie 95, no. 8 (2006): 579–96. http://dx.doi.org/10.1002/ange.19830950803.

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3

Raab, Michael, Gerold Schick, Rebecca Fondermann, et al. "Ein PH-funktionalisiertes Polyphosphazen: ein Makromolekül mit hochflexiblem Grundgerüst." Angewandte Chemie 118, no. 19 (2006): 3154–57. http://dx.doi.org/10.1002/ange.200504208.

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4

Schwoerer, M. "Sonderforschungsbereiche Stellen Sich Vor: SFB 213: TOPOMAC Topospezifische Chemie und Toposelektive Spektroskopie von Makromolekül-Systemen: Mikroskopische Wechselwirkung und makroskopische Funktion." Physik Journal 45, no. 10 (1989): 400–405. http://dx.doi.org/10.1002/phbl.19890451004.

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5

Çıracı, Enver, and Saadet Busra Aksoyer Sezgin. "Yaşlanma Sürecinde Mitokondrinin Rolü." ICONTECH INTERNATIONAL JOURNAL 4, no. 3 (2020): 1–10. http://dx.doi.org/10.46291/icontechvol4iss3pp1-10.

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ÖZET Mitokondri, hücresel fonksiyonlarda kullanılan ATP'yi üreten hücrenin güç merkezleri olarak tanımlanmaktadır. Mitokondriyal disfonksiyon yaşlanma sürecinin önemli bir parçasını oluşturmaktadır. Hücreler yaşlandıkça solunum zincirinin etkinliği azalmakta, elektron kaçağı artarak ve ATP oluşumunu azalmasına neden olmaktadır. Farklı hücre tipleri farklı sayıda mitokondriye sahiptir ve kendi DNA’larına sahip oldukları için, içinde bulundukları hücreden bağımsız olarak bölünebilmektedirler. Diğer bir ifadeyle, mitokondriyal replikasyon hücre bölünmesine bağlı değildir. Üreme sırasında, b

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6

Linscheid, Michael. "Aufgeklärte Makromoleküle." Chemie in unserer Zeit 36, no. 6 (2002): 405–7. http://dx.doi.org/10.1002/1521-3781(200212)36:6<405::aid-ciuz405>3.0.co;2-z.

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7

Molven, Anders. "Minileksikon om makromolekyl." Tidsskrift for Den norske legeforening 129, no. 1 (2009): 47. http://dx.doi.org/10.4045/tidsskr.2009.0420.

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8

Hermans, J. J. "Makromoleküle in Lösung." Recueil des Travaux Chimiques des Pays-Bas 63, no. 10 (2010): 205–10. http://dx.doi.org/10.1002/recl.19440631004.

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9

Käs, Josef A. "Polymerdynamik einzelner Makromoleküle." Chemie in unserer Zeit 29, no. 4 (1995): 207–10. http://dx.doi.org/10.1002/ciuz.19950290407.

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10

Pokrovskii, V. N. "Dynamics of weakly-coupled linear macromolecules." Uspekhi Fizicheskih Nauk 162, no. 5 (1992): 87. http://dx.doi.org/10.3367/ufnr.0162.199205b.0087.

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11

Darusman, Fitrianti, and Taufik Muhammad Fakih. "Studi Interaksi Senyawa Turunan Saponin dari Daun Bidara Arab (Ziziphus spina-christi L.) sebagai Antiseptik Alami secara In Silico." Jurnal Sains Farmasi & Klinis 7, no. 3 (2020): 229. http://dx.doi.org/10.25077/jsfk.7.3.229-235.2020.

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Christinin merupakan senyawa turunan glikosida saponin yang paling banyak terdapat dalam daun bidara arab (Ziziphus spina-christi L.). Terdapat empat tipe christinin yaitu christinin-A, B, C, dan D yang diduga memiliki aktivitas sebagai antimikroba yang efektif terhadap bakteri dan jamur, seperti Staphylococcus epidermidis, Echerichia coli, dan Candida albicans yang sering menyebabkan infeksi pada permukaan kulit yang biasanya dapat diatasi dengan penggunaan cairan antiseptik. Penelitian ini bertujuan untuk mengidentifikasi, mengevaluasi serta mengeksplorasi afinitas dan interaksi molekular an

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12

Darusman, Fitrianti, and Taufik Muhammad Fakih. "Studi Interaksi Senyawa Turunan Saponin dari Daun Bidara Arab (Ziziphus spina-christi L.) sebagai Antiseptik Alami secara In Silico." Jurnal Sains Farmasi & Klinis 7, no. 3 (2020): 233. http://dx.doi.org/10.25077/jsfk.7.3.233-239.2020.

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Christinin merupakan senyawa turunan glikosida saponin yang paling banyak terdapat dalam daun bidara arab (Ziziphus spina-christi L.). Terdapat empat tipe christinin yaitu christinin-A, B, C, dan D yang diduga memiliki aktivitas sebagai antimikroba yang efektif terhadap bakteri dan jamur, seperti Staphylococcus epidermidis, Echerichia coli, dan Candida albicans yang sering menyebabkan infeksi pada permukaan kulit yang biasanya dapat diatasi dengan penggunaan cairan antiseptik. Penelitian ini bertujuan untuk mengidentifikasi, mengevaluasi serta mengeksplorasi afinitas dan interaksi molekular an

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13

Deusing-Gottschalk, Ilka, and Petra Mischnick. "Makromoleküle - Strukturbildner mit besonderen Eigenschaften." CHEMKON 24, no. 4 (2017): 275–80. http://dx.doi.org/10.1002/ckon.201790010.

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14

Lanig, H. "Simulation biologischer Makromoleküle mit AMBER." Nachrichten aus Chemie, Technik und Laboratorium 46, no. 1 (1998): 37–40. http://dx.doi.org/10.1002/nadc.19980460118.

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15

Bryce, Martin R., Wayne Devonport, and Adrian J. Moore. "Dendritische Makromoleküle mit Tetrathiafulvalen-Einheiten." Angewandte Chemie 106, no. 17 (1994): 1862–64. http://dx.doi.org/10.1002/ange.19941061732.

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16

Burchard, Walther. "Walter Hugo Stockmayer (1914-2004): Makromoleküle." Angewandte Chemie 117, no. 12 (2005): 1782–83. http://dx.doi.org/10.1002/ange.200500381.

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17

Buntkowsky, Gerd, and Thomas Emmler. "Web Site: NMR-Daten biologischer Makromoleküle." Angewandte Chemie 114, no. 8 (2002): 1509. http://dx.doi.org/10.1002/1521-3757(20020415)114:8<1509::aid-ange1509>3.0.co;2-1.

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18

Heublein, G., P. Hortschansky, and S. Klein. "Zur adsorption flexibler Makromoleküle an Oxidgrenzflächen." Acta Polymerica 39, no. 3 (1988): 117–21. http://dx.doi.org/10.1002/actp.1988.010390305.

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19

Lomakin, A. V. "Study of the internal dynamics of macromolecules by the method of laser correlation spectroscopy." Uspekhi Fizicheskih Nauk 153, no. 10 (1987): 360. http://dx.doi.org/10.3367/ufnr.0153.198710j.0360.

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20

Fakih, Taufik Muhammad, and Mentari Luthfika Dewi. "Studi Interaksi Molekuler Aktivitas Antimikroba Peptida Bioaktif terhadap Staphylococcus aureus Secara In silico." JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA 7, no. 2 (2020): 93. http://dx.doi.org/10.20473/jfiki.v7i22020.93-99.

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Pendahuluan: Lendir kulit ikan lele kuning (Pelteobagrus fulvidraco), mengandung peptida bioaktif dan banyak dimanfaatkan dalam pengobatan berbagai penyakit karena memiliki aktivitas biologis, diantaranya sebagai antimikroba. Beberapa peptida bioaktif tersebut, antara lain pelteobagrin, myxinidin, pleurocidin, dan pardaxin-P1 dan telah terbukti mampu menghambat Penicillin-Binding Protein 3 (PBP3) dari Staphylococcus aureus. Tujuan: Penelitian ini bertujuan untuk mengidentifikasi aktivitas antimikroba molekul peptida bioaktif secara in silico terhadap makromolekul Penicillin-Binding Protein 3 (

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21

Sadowski, G. "Moderne Zustandsgleichungen für Gase, Lösungsmittel und Makromoleküle." Chemie Ingenieur Technik 72, no. 9 (2000): 975–76. http://dx.doi.org/10.1002/1522-2640(200009)72:9<975::aid-cite9750>3.0.co;2-5.

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22

Schierbaum, Friedrich. "Book Reviews: Makromoleküle. By Hans-Georg Elias." Starch - Stärke 56, no. 6 (2004): 264–65. http://dx.doi.org/10.1002/star.200490028.

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23

Solleder, Susanne C., Deniz Zengel, Katharina S. Wetzel, and Michael A. R. Meier. "Eine skalierbare Synthese sequenzdefinierter Makromoleküle mit hohen Ausbeuten." Angewandte Chemie 128, no. 3 (2015): 1222–25. http://dx.doi.org/10.1002/ange.201509398.

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24

Schneider, André. "Eine Translokase für Makromoleküle in Mitochondrien von Trypanosomen." BIOspektrum 25, no. 5 (2019): 504–6. http://dx.doi.org/10.1007/s12268-019-1085-z.

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25

Okuda, Jun. "Synthese optisch aktiver Makromoleküle mit löslichen Metallocen-Katalysatoren." Angewandte Chemie 104, no. 1 (1992): 49–50. http://dx.doi.org/10.1002/ange.19921040107.

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26

Fakih, Taufik Muhammad, and Mentari Luthfika Dewi. "Identifikasi Mekanisme Fungsional Senyawa Bioaktif Peptida dari Organisme Laut sebagai Inhibitor Alami Angiotensin-I Converting Enzyme (ACE) secara In silico." Majalah Farmasi dan Farmakologi 24, no. 1 (2020): 17–21. http://dx.doi.org/10.20956/mff.v24i1.9647.

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Inhibitor alami Angiotensin-I Converting Enzyme (ACE) berbasis peptida bioaktif saat ini menjadi fokus penelitian karena sifatnya yang unik dan memilki berbagai peran biologis penting diantaranya adalah sebagai kandidat pengobatan hipertensi. Terdapat beberapa peptida bioaktif yang dihasilkan oleh organisme laut dan telah terbukti mampu menghambat enzim ACE, antara lain peptida bioaktif yang berasal dari udang (SV, IF, dan WP) serta peptida bioaktif yang berasal dari ikan hiu (CF, EY, MF, dan FE). Pada penelitian ini dilakukan identifikasi, evaluasi, dan eksplorasi terhadap interaksi yang terj

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27

Hasan, Rahmawaty, Fauzah Cholashotul I’anah, and Rizky Resvita R Bahi. "STUDI BIOINFORMATIKA KANDUNGAN KIMIA DAUN KELOR (Moringa oleifera) TERHADAP TARGET AKSI PEMENUHAN ZAT GIZI IBU HAMIL." Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) 17, no. 2 (2022): 337–43. http://dx.doi.org/10.36911/pannmed.v17i2.1346.

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Asam folat merupakan mikronutrien yang sangat diperlukan oleh ibu hamil dalam perkembangan sistem saraf. Konsumsi daun kelor dapat meningkatkan kadar hemoglobin yaitu >11 gr%. Potensi zat gizi yang terkandung dalam daun kelor mampu memenuhi kebutuhan zat gizi ibu hamil. Namun identifikasi senyawa aktif tersebut terhadap makromolekul atau target aksi molekuler asam folat belum diketahui dengan jelas. Penelitian ini bertujuan untuk mengidentifikasi kandungan kimia daun kelor yang dapat berinteraksi dengan reseptor folat secara in silico serta prediksi parameter farmakokinetika basis webserver

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28

Volker Drach, D. R. "Röntgenstrahlbeugung an DNA-Membran-Komplexen Komplexe Makromoleküle organisieren sich." Physik in unserer Zeit 30, no. 1 (1999): 35. http://dx.doi.org/10.1002/piuz.19990300107.

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29

May, Roland P. "Von Donuts und Zucker: Mit Neutronen biologische Makromoleküle erforschen." Physik in unserer Zeit 34, no. 3 (2003): 119–25. http://dx.doi.org/10.1002/piuz.200390054.

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30

Lederer, Albena, Walther Burchard, Tobias Hartmann, et al. "Dendronisierte hochverzweigte Makromoleküle: weiche Materie mit einer neuartigen Segmentverteilung." Angewandte Chemie 127, no. 43 (2015): 12764–70. http://dx.doi.org/10.1002/ange.201504059.

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31

Mutlu, Hatice, and Jean-François Lutz. "“Lesen” von Polymeren: Die Sequenzierung natürlicher und synthetischer Makromoleküle." Angewandte Chemie 126, no. 48 (2014): 13224–33. http://dx.doi.org/10.1002/ange.201406766.

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32

Hanistya, Ria, Tristiana Erawati, Cita Rosita Sigit Prakoeswa, Fedik Abdul Rantam, and Widji Soeratri. "Pengaruh Penambahan SPACE terhadap Karakteristik dan Stabilitas Gel Freeze Dried Amniotic Membrane Stem Cell-Metabolite Product." JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA 7, no. 2 (2020): 59. http://dx.doi.org/10.20473/jfiki.v7i22020.59-65.

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Pendahuluan: Sebagai organ terluas yang menyusun tubuh manusia, kulit menjadi salah satu lokasi penting dalam menghantarkan obat atau bahan aktif tertentu ke dalam tubuh manusia. Beberapa bahan aktif berbentuk makromolekul dengan berat molekul lebih dari 500 Da tidak dapat menembus stratum korneum sehingga membutuhkan bantuan penetration enhancer. SPACE (Skin Penetrating and Cell Entering) merupakan rangkaian molekul peptida berukuran kecil yang berpotensi bekerja sebagai enhancer dalam menghantarkan makromolekul dengan cara yang tidak invasif. Namun SPACE merupakan enhancer golongan baru sehi

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33

Signer, R., and H. Egli. "Sedimentation von Makromolekülen und Durchströmung von Gelen." Recueil des Travaux Chimiques des Pays-Bas 69, no. 1 (2010): 45–58. http://dx.doi.org/10.1002/recl.19500690107.

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34

Frey, Holger, and Holger Kautz. "Hyperverzweigte Polymere: von baumartigen Makromolekülen zu Funktionsmaterialien." Nachrichten aus der Chemie 50, no. 11 (2002): 1218–24. http://dx.doi.org/10.1002/nadc.20020501108.

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35

Pahnke, Kai, Josef Brandt, Ganna Gryn'ova, et al. "Entropisch bedingte Selektivität der Kettenspaltung oder: Wo Makromoleküle sich trennen." Angewandte Chemie 128, no. 4 (2015): 1537–41. http://dx.doi.org/10.1002/ange.201508531.

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36

Schnecko, Hans W. "Makromoleküle. Band 4: Anwendungen von Polymeren. Von Hans-Georg Elias." Angewandte Chemie 115, no. 36 (2003): 4417. http://dx.doi.org/10.1002/ange.200385989.

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37

Schnecko, Hans W. "Makromoleküle. Band 4: Anwendungen von Polymeren. By Hans-Georg Elias." Angewandte Chemie International Edition 42, no. 36 (2003): 4283. http://dx.doi.org/10.1002/anie.200385989.

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38

Wüthrich, Kurt. "NMR-Untersuchungen von Struktur und Funktion biologischer Makromoleküle (Nobel-Vortrag)." Angewandte Chemie 115, no. 29 (2003): 3462–86. http://dx.doi.org/10.1002/ange.200300595.

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39

Lederer, Albena, Walther Burchard, Tobias Hartmann, et al. "Frontispiz: Dendronisierte hochverzweigte Makromoleküle: weiche Materie mit einer neuartigen Segmentverteilung." Angewandte Chemie 127, no. 43 (2015): n/a. http://dx.doi.org/10.1002/ange.201584361.

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40

Hanif, Atika Umi, Prima Agusti Lukis, and Arif Fadlan. "Pengaruh Minimisasi Energi MMFF94 dengan MarvinSketch dan Open Babel PyRx pada Penambatan Molekular Turunan Oksindola Tersubstitusi." ALCHEMY 8, no. 2 (2020): 33–40. http://dx.doi.org/10.18860/al.v8i2.10481.

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In silico technique is widely used for drug discovery because it can predict the conformation of ligands in protein macromolecules and it can calculate the binding affinity. The energy minimization is carried out to make the ligand more stable near the initial state during molecular docking process. The Merck Molecular Force Field (MMFF94) is one type of energy minimization process often used in organic compounds. The molecular docking of substituted oxindole derivatives on indoleamine macromolecules 2,3-dioxygenase (IDO-1, PDB: 2D0T) by MMFF94 minimization operated by MarvinSketch and Open Ba

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41

Maiz Fernández, Sheila, and Leyre Pérez Álvarez. "Azido hialuroniko nanogelak." EKAIA Euskal Herriko Unibertsitateko Zientzia eta Teknologia Aldizkaria, no. 32 (November 7, 2017): 137–50. http://dx.doi.org/10.1387/ekaia.17857.

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Azido hialuronikoa (AH) izaki bizidun guztien zelulaz kanpoko matrizean (ECM) aurkitzen den polisakarido lineala da. Naturan dauden polimeroen artean aplikazio gehien dituena da. Biobateragarria, ez-zitotoxikoa eta biodegradagarria den makromolekula honek eskala nanometrikoan sintetizatzen denean, ezaugarri ezin hobeak aurkezten dituzten nanogelak garatzeko aukera paregabea eskaintzen du. Lan honetan azido hialuronikoaren eta bere nanogelen sintesi-metodoak, ezaugarriak eta erabilerak laburki deskribatuko dira, nanogel hauen potentziala biomedikuntzaren arloan jakinarazteko asmotan.

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42

Prosi, M., and K. Perktold. "MATHEMATISCHE UND NUMERISCHE TRANSPORTMODELLE VON MAKROMOLEKÜLEN IN ARTERIENWÄNDEN." Biomedizinische Technik/Biomedical Engineering 48, s1 (2003): 84–85. http://dx.doi.org/10.1515/bmte.2003.48.s1.84.

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43

Hiltebrandt, Kai, Thomas Pauloehrl, James P. Blinco, Katharina Linkert, Hans G. Börner та Christopher Barner-Kowollik. "λ-Orthogonale Photochemie: Lichtinduzierte pericyclische Reaktionen an Makromolekülen". Angewandte Chemie 127, № 9 (2015): 2880–85. http://dx.doi.org/10.1002/ange.201410789.

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44

Hänsel, Robert, Laura M. Luh, Ivan Corbeski, Lukáš Trantirek, and Volker Dötsch. "Intrazelluläre NMR- und EPR-Spektroskopie von biologischen Makromolekülen." Angewandte Chemie 126, no. 39 (2014): 10466–80. http://dx.doi.org/10.1002/ange.201311320.

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45

Wintermantel, Matthias, Manfred Schmidt, Alfons Becker, Andreas Kühn, and Rainer Lösch. "Polymeranalytik: Strukturbestimmung von Makromolekülen mit der Gelpermeations-Chromatographie." Nachrichten aus Chemie, Technik und Laboratorium 40, no. 3 (1992): 331–38. http://dx.doi.org/10.1002/nadc.19920400309.

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46

Silverstein, Michael S. "From “Makromolekel” to POLYMER: A Centennial Celebration of Staudinger's “On Polymerization”." Polymer 215 (February 2021): 123409. http://dx.doi.org/10.1016/j.polymer.2021.123409.

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47

Türk, Thomas, Jörn Probst, Bernd Priessnitz, and Roger Thull. "Änderung optischer Eigenschaften adsorbierter Makromoleküle zur Bestimmung von Feldgradienten an Implantatoberflächen." Biomedizinische Technik/Biomedical Engineering 38, s1 (1993): 135–36. http://dx.doi.org/10.1515/bmte.1993.38.s1.135.

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48

Millitzer, M., E. Wenzig, and W. Peukert. "In situ-Adsorption biotechnologisch hergestellter Makromoleküle zur Optimierung des Downstream Processing." Chemie Ingenieur Technik 74, no. 1-2 (2002): 152–55. http://dx.doi.org/10.1002/1522-2640(200202)74:1/2<152::aid-cite152>3.0.co;2-0.

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49

Schmidt-Naake, G. "Buchbesprechung: Makromoleküle, Band 4: Anwendungen von Polymeren. Von H.-G. Elias." Chemie Ingenieur Technik 76, no. 12 (2004): 145–46. http://dx.doi.org/10.1002/cite.200490000.

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50

Haag, Rainer, and Fritz Vögtle. "Hochverzweigte Makromoleküle an der Schnittstelle zwischen Chemie, Biologie, Physik und Medizin." Angewandte Chemie 116, no. 3 (2004): 274–75. http://dx.doi.org/10.1002/ange.200320082.

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