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Journal articles on the topic 'Malaria diagnosis in medical laboratory'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Makler, Michael T., and Bruce Gibbins. "Laboratory Diagnosis of Malaria." Clinics in Laboratory Medicine 11, no. 4 (1991): 941–56. http://dx.doi.org/10.1016/s0272-2712(18)30529-8.

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2

Mukry, Samina Naz, Madiha Saud, Gul Sufaida, Kashif Shaikh, Arshi Naz, and Tahir Sultan Shamsi. "Laboratory Diagnosis of Malaria: Comparison of Manual and Automated Diagnostic Tests." Canadian Journal of Infectious Diseases and Medical Microbiology 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/9286392.

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Malaria is the second most prevalent disease in Pakistan resulting in ~30,000 annual deaths. In endemic countries like Pakistan precise and timely diagnosis of malaria is imperative to overcome the associated risks of fatal outcomes. Malarial parasite was screened in 128 malaria suspected patients and 150 healthy controls, by species-specific PCR, microscopy of blood smears, hemoanalyzer Sysmex XE-2100, and rapid test devices (First Response Malaria® and ICT Malaria Combo®). The microscopy detected MP in 126 samples (parasite load/µl 386–53712/µl); 71.094% were infected withPlasmodium vivaxand

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3

Wilson, Michael L. "Laboratory Diagnosis of Malaria: Conventional and Rapid Diagnostic Methods." Archives of Pathology & Laboratory Medicine 137, no. 6 (2013): 805–11. http://dx.doi.org/10.5858/arpa.2011-0602-ra.

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Context.—The global control of malaria is more challenging than that of many other infectious diseases: malaria is vector borne, it is caused by 5 species of Plasmodium with different geographic distributions, infection is widespread in many regions, drug resistance is common, and the disease overlaps clinically with other infectious diseases. Therefore, malaria control programs, in addition to diagnosis and testing, must also target limiting spread of the disease through vector control. Although malaria control efforts have been successful in some regions, malaria remains one of the most impo

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Johnston, S. P., N. J. Pieniazek, M. V. Xayavong, S. B. Slemenda, P. P. Wilkins, and A. J. da Silva. "PCR as a Confirmatory Technique for Laboratory Diagnosis of Malaria." Journal of Clinical Microbiology 44, no. 3 (2006): 1087–89. http://dx.doi.org/10.1128/jcm.44.3.1087-1089.2006.

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5

Ozeryanskaya, A. Yu, and S. P. Kazakov. "Clinical case of malaria determining using modern laboratory diagnostics methods." Medical alphabet 3, no. 32 (2020): 19–23. http://dx.doi.org/10.33667/2078-5631-2019-3-32(407)-19-23.

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The article describes a clinical case of malaria in patient X., who was admitted to the medical institution of the Ministry of Defense. The patient was diagnosed with acute leukemia based on complaints and the clinical picture, followed by transferring the patient to the hematology centre of the Main Military Clinical Hospital n. a. N. N. Burdenko. In a short time, the patient was diagnosed with laboratory tests of the Department of Clinical and Hematological Research, and the diagnosis was reported to the specialists of the hematological centre. The patient was promptly provided with the nece

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Mathison, Blaine A., and Bobbi S. Pritt. "Update on Malaria Diagnostics and Test Utilization." Journal of Clinical Microbiology 55, no. 7 (2017): 2009–17. http://dx.doi.org/10.1128/jcm.02562-16.

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ABSTRACT Malaria is a potentially life-threatening disease requiring rapid diagnosis and treatment. Although microscopic examination of thick and thin blood films remains the gold standard for laboratory diagnosis, rapid antigen tests and nucleic acid amplification methods may also play a useful role in detection of acute infection. This review discusses the advantages and disadvantages of the commonly used diagnostic methods and provides important practice points for optimal malaria test utilization.

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Church, Deirdre L., Angelika Lichtenfeld, Sameer Elsayed, Susan Kuhn, and Daniel B. Gregson. "A Regional Centralized Microbiology Service in Calgary for the Rapid Diagnosis of Malaria." Archives of Pathology & Laboratory Medicine 127, no. 6 (2003): 687–93. http://dx.doi.org/10.5858/2003-127-687-arcmsi.

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Abstract Context.—A regional centralized laboratory service for the rapid diagnosis of malaria was implemented 3 years ago in May 1999 within the Division of Microbiology, Calgary Laboratory Services. Objective.—To describe the design and performance of this unique microbiology laboratory service. Design.—Blood specimens must arrive at the central laboratory within 2 hours of collection. Thin blood smears are read and reported from suspected acute cases within 1 hour of receipt, 24 hours per day, 7 days a week, by trained and experienced microbiology technologists. All positive malaria smears

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Kotepui, Kwuntida Uthaisar, Manas Kotepui, and Chuchard Punsawad. "Knowledge, Attitude, and Practice Related to Malaria Diagnosis among Healthcare Workers in Hospitals: A Cross-Sectional Survey." Journal of Tropical Medicine 2019 (June 11, 2019): 1–9. http://dx.doi.org/10.1155/2019/1414079.

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Malaria is a potential medical emergency and should be treated immediately because delays in diagnosis and treatment are the leading causes of death in many countries. This study aimed to assess the knowledge, attitude, and practice related to malaria diagnosis for early detection among healthcare workers in the laboratories of hospitals in Thailand. The design of the study was a descriptive cross-sectional study carried out between January 2016 and March 2017 at 11 hospitals in Thailand. The interviewees included any scientists who were currently working in a medical laboratory. Mean scores f

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Rubio, J. M., A. Benito, P. J. Berzosa, et al. "Usefulness of Seminested Multiplex PCR in Surveillance of Imported Malaria in Spain." Journal of Clinical Microbiology 37, no. 10 (1999): 3260–64. http://dx.doi.org/10.1128/jcm.37.10.3260-3264.1999.

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The use of a new PCR-based method for the diagnosis of malaria in the Spanish Malaria Reference Laboratory has promoted an increase in confirmed cases of malaria. From August 1997 to July 1998, a total of 192 whole-blood samples and 71 serum samples from 168 patients were received from the hospitals of the Spanish National Health System. Most of the patients came from west-central African countries (85%). This molecular method showed more sensitivity and specificity than microscopy, detecting 12.4% more positive samples than microscopy and 13% of mixed infections undetectable by Giemsa stain.

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10

Kukina, I. V., O. P. Zelya, and L. S. Karan. "LABORATORY DIAGNOSTIC OF HUMAN BABESIOSIS." Russian Clinical Laboratory Diagnostics 64, no. 9 (2019): 560–64. http://dx.doi.org/10.18821/0869-2084-2019-64-9-560-564.

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Human babesiosis caused by parasitic protozoan Babesia spp. is sporadic zoonotic vector-borne infection. The course of babesiosis and prognosis depend on the type of pathogen and on the patient’s immunological status. Significance this disease is a severe, often fatal course with immunocompromissed patients resembling complicated falciparum malaria. In Europe to date, more than 50 cases of confirmed human babesiosis have been reported in most cases caused by Babesia divergens. Possible there are unrecognized cases. Pathogen is an obligate intraerythrocyte parasite of vertebrate animals. The or

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11

Gjørup, Ida E., Lasse S. Vestergaard, Kirsten Møller, Anita M. Rønn, and Ib C. Bygbjerg. "Laboratory indicators of the diagnosis and course of imported malaria." Scandinavian Journal of Infectious Diseases 39, no. 8 (2007): 707–13. http://dx.doi.org/10.1080/00365540701225710.

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12

Dougnon, T. V., H. S. Bankole, Y. M. G. Hounmanou, S. Echebiri, P. Atchade, and J. Mohammed. "Comparative Study of Malaria Prevalence among Travellers in Nigeria (West Africa) Using Slide Microscopy and a Rapid Diagnosis Test." Journal of Parasitology Research 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/108707.

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Malaria is a major disease in Africa and leads to various public health problems. A study was carried out at the Aviation Medical Clinic Laboratory, Murtala Mohammed Airport, Ikeja, Lagos State, Nigeria, in 2014. The work aimed to determine the prevalence of malaria among patients attending the laboratory. Blood samples were therefore collected from 51 patients and subjected to both blood smear microscopy and a rapid immunochromatographic diagnostic test (SD BIOLINE Malaria Ag) for detection of, respectively, malaria parasites and antigens. At the end of the study, 22% of the patients were det

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13

Rao, Mohan, Nurul Atiqah, Mukmina Dasiman, and Fairuz Amran. "Demographic, clinical and laboratory features of leptospirosis–malaria co-infections in Peninsular Malaysia." Journal of Medical Microbiology 69, no. 3 (2020): 451–56. http://dx.doi.org/10.1099/jmm.0.001127.

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Introduction. Co-infection of leptospirosis–malaria is not uncommon due to their overlapping geographical distribution in the tropics. Aim. This study aimed to describe and compare the demographic, clinical and laboratory features of leptospirosis–malaria co-infection (LMCI) against leptospirosis mono-infection (LMI) in Peninsular Malaysia. Methodology. Data of patients admitted to various hospitals in Peninsular Malaysia from 2011 to 2014 diagnosed with leptospirosis in our laboratory were obtained from their admission records. Co-infections with malaria were identified via blood film for mal

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Sergiev, V. P., A. M. Baranova, G. M. Kozhevnikova, et al. "Problems of clinical diagnosis and treatment of P. falciparum malaria in Russian Federation." Terapevticheskii arkhiv 90, no. 11 (2018): 4–8. http://dx.doi.org/10.26442/terarkh201890114-8.

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Aim. To study the causes of falciparum malaria deaths in Russian Federation and to optimize therapy for severe forms of the disease. Materials and methods. The analysis of falciparum malaria cases with deaths recorded in Russian Federation from 2013 to 2017 was conducted. The results of optimization of pathogenetic therapy of severe forms of falciparum malaria for the prevention of adverse outcomes in the intensive care unit of the Infectious Clinical Hospital №2 of Moscow in 44 patients with severe course are presented. Treatment, clinical laboratory and instrumental investigations were carri

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15

Rehman, Amjad, Naveed Abbas, Tanzila Saba, Zahid Mehmood, Toqeer Mahmood, and Khawaja Tehseen Ahmed. "Microscopic malaria parasitemia diagnosis and grading on benchmark datasets." Microscopy Research and Technique 81, no. 9 (2018): 1042–58. http://dx.doi.org/10.1002/jemt.23071.

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16

Jelinek, T., M. P. Grobusch, S. Schwenke, et al. "Sensitivity and Specificity of Dipstick Tests for Rapid Diagnosis of Malaria in Nonimmune Travelers." Journal of Clinical Microbiology 37, no. 3 (1999): 721–23. http://dx.doi.org/10.1128/jcm.37.3.721-723.1999.

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Swift diagnosis of Plasmodium falciparum malaria in areas where the disease is not endemic is frequently complicated by the lack of experience on the side of involved laboratory personal. Diagnostic tools based on the dipstick principle for the detection of plasmodial histidine-rich protein 2 (HRP-2) and parasite-specific lactate dehydrogenase (pLDH), respectively, have become available for the qualitative detection of P. falciparum malaria. In order to evaluate two of the currently available assays, specimens from 231 patients were screened during a prospective multicenter study. Among the sc

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White, Valerie A. "Malaria in Malawi: Inside a Research Autopsy Study of Pediatric Cerebral Malaria." Archives of Pathology & Laboratory Medicine 135, no. 2 (2011): 220–26. http://dx.doi.org/10.5858/135.2.220.

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Abstract Context.—Malaria is still a major cause of death in sub-Saharan Africa. Objectives.—To describe my participation as a pathologist in a research autopsy study in Malawi and to examine retinal pathologic findings in cerebral malaria and correlate them with those in the brain. To describe the challenges of conducting a research study in sub-Saharan Africa and the personal and scientific benefits resulting from this. Design.—Children with coma are admitted to the pediatric research ward, classified according to the clinical definition of severe malaria or another cause of coma, evaluated,

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18

Alweis, Richard L., Kerrie DiRosario, Giuseppe Conidi, Kevin C. Kain, Richard Olans, and John L. Tully. "Serial Nosocomial Transmission of Plasmodium falciparum Malaria From Patient to Nurse to Patient." Infection Control & Hospital Epidemiology 25, no. 1 (2004): 55–59. http://dx.doi.org/10.1086/502293.

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AbstractBackground:Nosocomial transmission of malaria is a rare phenomenon in the United States.Objective:To describe the probable transmission of Plasmodium falciparum malaria from a patient to a healthcare worker and then from the healthcare worker to another patient.Design:Case series.Setting:Two community hospitals in Massachusetts.Intervention:Routine medical and supportive care.Measurements:Clinical and laboratory evaluation.Results:A nurse developed falciparum malaria after a needlestick injury from a patient with documented falciparum malaria. Three days prior to her diagnosis, she car

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19

Reddy A., Bhaskar, Deepthi K. N., and Zion Eluzai. "Efficacy of rapid test as an aid in rapid diagnosis of malaria at bed side in an endemic region in comparison to conventional microscopy." International Journal of Contemporary Pediatrics 5, no. 4 (2018): 1442. http://dx.doi.org/10.18203/2349-3291.ijcp20182543.

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Background: The routine and commonly used test for malaria diagnosis is obtaining thick and thin smears and examining it under microscope. This test required skilled laboratory and skilled staff. Hence rapid diagnostic kits have been developed. Present study attempts to study the efficacy of this optical test in the diagnosis of malaria among children. Objectives of present study was to study efficacy of rapid test in rapid diagnosis of malaria at bed side in an endemic region.Methods: Hospital based cross sectional diagnostic evaluation study was carried out at SVS Medical College, Mahabubnag

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20

Rypien, Candace, Barbara Chow, Wilson W. Chan, Deirdre L. Church, and Dylan R. Pillai. "Detection of Plasmodium Infection by the illumigene Malaria Assay Compared to Reference Microscopy and Real-Time PCR." Journal of Clinical Microbiology 55, no. 10 (2017): 3037–45. http://dx.doi.org/10.1128/jcm.00806-17.

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ABSTRACT Malaria is one of the leading causes of infectious disease in travelers returning from the tropics. The diagnosis of malaria is typically performed by examining Giemsa-stained thick and thin peripheral blood smears, which is time consuming, labor intensive, and requires high levels of proficiency. Alternatively, loop-mediated isothermal amplification (LAMP) is a new molecular method, which is rapid, sensitive, and requires less capital equipment and technological training. We conducted a retrospective study comparing two formats of a commercial LAMP assay (Meridian illumi gene malaria

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Berrang-Ford, L., J. D. MacLean, Theresa W. Gyorkos, J. D. Ford, and N. H. Ogden. "Climate Change and Malaria in Canada: A Systems Approach." Interdisciplinary Perspectives on Infectious Diseases 2009 (2009): 1–13. http://dx.doi.org/10.1155/2009/385487.

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This article examines the potential for changes in imported and autochthonous malaria incidence in Canada as a consequence of climate change. Drawing on a systems framework, we qualitatively characterize and assess the potential direct and indirect impact of climate change on malaria in Canada within the context of other concurrent ecological and social trends. Competent malaria vectors currently exist in southern Canada, including within this range several major urban centres, and conditions here have historically supported endemic malaria transmission. Climate change will increase the occurr

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Wenk, Robert E., and Ina Stephens. "Erythrocyte Fy Antigen Phenotyping Helps Differentiate So-called Benign Tertian Malarias." Archives of Pathology & Laboratory Medicine 124, no. 2 (2000): 299–301. http://dx.doi.org/10.5858/2000-124-0299-efaphd.

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Abstract Isolated cases of malaria are increasing in frequency in nonendemic countries. Blood film examination remains a mainstay of diagnosis of these sporadic cases because immunologic and molecular methods are unavailable, expensive, and problematic. Two tertian malarial species, Plasmodium vivax and Plasmodium ovale, may appear to be similar morphologically. Plasmodium ovale infection is infrequent, and misdiagnosis of this species is common. Plasmodium vivax infection can be ruled out, however, if a patient's erythrocytes phenotype as Fy(a−b−), because these cells completely resist entry

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Bekoe, Andrew Nii Adzei, Emmanuel Alote Allotey, Elliot Elikplim Akorsu, et al. "Inter-rater Variability in Malaria Microscopy at the LEKMA Hospital, Ghana." Journal of Parasitology Research 2020 (December 4, 2020): 1–6. http://dx.doi.org/10.1155/2020/8897337.

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Background. Malaria remains a major cause of morbidity and mortality worldwide and particularly in sub-Saharan Africa where it is endemic. As such, it is important that a proper diagnosis is made before treatment is initiated. Malaria parasite count plays a key role in the diagnosis and management of malaria. Variations in ratings by laboratory personnel can impact negatively on the treatment regimen for malaria-infected patients. The study is thus aimed at evaluating and comparing the proficiency and parasitaemia counts by two different categories of laboratory staff at the LEKMA Hospital, Gh

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Collins-Andrews, Benetta, Patricia McQuilkin, Kanagasabai Udhayashankar, Eric Adu, and Ann Moormann. "Presentation and Treatment Outcomes of Liberian Children Age 5 Years and Under Diagnosed With Severe Malaria." Global Pediatric Health 6 (January 2019): 2333794X1988481. http://dx.doi.org/10.1177/2333794x19884818.

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Malaria is endemic in Liberia with a prevalence rate of up to 60% in some regions, and it has been a major cause of death in children under 5 years of age. Prior to the recent Ebola epidemic, we undertook a prospective, hospital-based pilot study at the National Referral Hospital in Monrovia, to characterize the presentation, accuracy of diagnosis, and treatment outcomes of children presenting for treatment of malaria. From June 2013 to May 2014, we recruited children 5 years and under who presented to the JFK Medical Center with suspected malaria. We collected both clinical and laboratory dat

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Chouhan, Dr Swati, and Dr Siddharth Gautam Singh. "Evaluation of markers of thrombosis and fibrinolysis in malaria patients in tertiary care hospital in Central India." Tropical Journal of Pathology and Microbiology 6, no. 8 (2020): 498–503. http://dx.doi.org/10.17511/jopm.2020.i08.07.

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Background: Cases of malaria are known to be associated with variable degrees of coagulopathy asevident from abnormalities of screening coagulation assays in a large number of patients during theillness. However, attempts to use laboratory parameters as indicators of the severity of theunderlying coagulopathy and for monitoring disease progression have met with only partial success.Methods: This prospective study was conducted in the department of Pathology in RuxmanibenDeepchand Gardi Medical College, Ujjain. Blood samples of all the patients diagnosed positive withmalaria were collected in v

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Masud, Mehedi, Hesham Alhumyani, Sultan S. Alshamrani, et al. "Leveraging Deep Learning Techniques for Malaria Parasite Detection Using Mobile Application." Wireless Communications and Mobile Computing 2020 (July 8, 2020): 1–15. http://dx.doi.org/10.1155/2020/8895429.

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Malaria is a contagious disease that affects millions of lives every year. Traditional diagnosis of malaria in laboratory requires an experienced person and careful inspection to discriminate healthy and infected red blood cells (RBCs). It is also very time-consuming and may produce inaccurate reports due to human errors. Cognitive computing and deep learning algorithms simulate human intelligence to make better human decisions in applications like sentiment analysis, speech recognition, face detection, disease detection, and prediction. Due to the advancement of cognitive computing and machin

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Moody, Anthony. "Rapid Diagnostic Tests for Malaria Parasites." Clinical Microbiology Reviews 15, no. 1 (2002): 66–78. http://dx.doi.org/10.1128/cmr.15.1.66-78.2002.

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SUMMARY Malaria presents a diagnostic challenge to laboratories in most countries. Endemic malaria, population movements, and travelers all contribute to presenting the laboratory with diagnostic problems for which it may have little expertise available. Drug resistance and genetic variation has altered many accepted morphological appearances of malaria species, and new technology has given an opportunity to review available procedures. Concurrently the World Health Organization has opened a dialogue with scientists, clinicians, and manufacturers on the realistic possibilities for developing a

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Ndao, Momar. "Diagnosis of Parasitic Diseases: Old and New Approaches." Interdisciplinary Perspectives on Infectious Diseases 2009 (2009): 1–15. http://dx.doi.org/10.1155/2009/278246.

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Methods for the diagnosis of infectious diseases have stagnated in the last 20–30 years. Few major advances in clinical diagnostic testing have been made since the introduction of PCR, although new technologies are being investigated. Many tests that form the backbone of the “modern” microbiology laboratory are based on very old and labour-intensive technologies such as microscopy for malaria. Pressing needs include more rapid tests without sacrificing sensitivity, value-added tests, and point-of-care tests for both high- and low-resource settings. In recent years, research has been focused on

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Khan, Inamullah, Hassan Rehman, Shafaq Naz, and Zafar Haya. "FALCIPARUM MALARIA." Professional Medical Journal 21, no. 02 (2018): 253–57. http://dx.doi.org/10.29309/tpmj/2014.21.02.2045.

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Objective: To determine how Falciparum Malaria can present clinically in various ways. A study conducted on 150 admitted patients. Subjects and Methods: This descriptive case-series, single center study was conducted in Medical B Unit, Khyber Teaching Hospital, Peshawar from November 2012 to June 2013. A total of 150 patients admitted with falciparum malaria were studied. A detailed history and clinical examination was performed. The falciparum malaria was diagnosed by examining peripheral blood film. All patients were thoroughly investigated to find out the complications of falciparum malaria

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Udoh, Ekong, Angela Oyo-ita, Friday Odey, et al. "Management of Uncomplicated Malaria in Underfives in Private and Public Health Facilities in South-Eastern Nigeria: A Clinical Audit of Current Practices." Malaria Research and Treatment 2013 (January 21, 2013): 1–6. http://dx.doi.org/10.1155/2013/575080.

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Malaria remains a leading cause of underfive morbidity and mortality in sub-Saharan Africa. Effective case management is a strategy recommended by the World Health Organization for its control. A clinical audit of case management of uncomplicated malaria in underfives in health facilities in Cross River State, Nigeria, was conducted from January to March 2012. Data was extracted from patients’ case records by trained medical personnel using pretested data extraction forms. Of the 463 case records reviewed, age, gender, and weight were reported in 98.1%, 97.3%, and 49.7% of the children, respec

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Simon, Achankeng Nkemasong. "Comparison of Patients’ Self-Diagnosis of Malaria and their Test Results from Medical Laboratory Analysis: The Case of Limbe Regional Hospital." TEXILA INTERNATIONAL JOURNAL OF PUBLIC HEALTH 4, no. 2 (2016): 85–102. http://dx.doi.org/10.21522/tijph.2013.04.02.art027.

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Mbunga, Branly Kilola, Mala Ali Mapatano, Tor A. Strand, Elin Lovise F. Gjengedal, Pierre Zalagile Akilimali, and Ingunn Marie S. Engebretsen. "Prevalence of Anemia, Iron-Deficiency Anemia, and Associated Factors among Children Aged 1–5 Years in the Rural, Malaria-Endemic Setting of Popokabaka, Democratic Republic of Congo: A Cross-Sectional Study." Nutrients 13, no. 3 (2021): 1010. http://dx.doi.org/10.3390/nu13031010.

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Iron deficiency (ID), the leading cause of anemia and the most common nutritional deficiency globally, is not well reported among children in malaria-endemic settings, and little is known about its contribution to anemia in these settings. We aimed to assess the prevalence of anemia, the role of ID using multiple parameters, and the factors associated with anemia in a malaria-endemic rural area. We conducted a community-based cross-sectional study of 432 children aged 1–5 years from the Popokabaka Health Zone, Democratic Republic of Congo. Sociodemographic characteristics, medical history, ant

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Roumpou, Afroditi, Ioanna Papaioannou, and Christos Lampropoulos. "Weil’s disease with haemoptysis and acute respiratory distress syndrome." BMJ Case Reports 12, no. 5 (2019): e229350. http://dx.doi.org/10.1136/bcr-2019-229350.

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A 35-year-old male patient reached the emergency department after an episode of massive haemoptysis a few hours ago. Fever and dyspnea were mentioned to be present the last 5 days. His medical history included only malaria, successfully treated 2 years ago. Clinical examination revealed high fever, jaundice, cyanosis, tachypnea and bilateral rales on pulmonary auscultation. Laboratory investigation showed high erythrocyte sedimentation rate and C reactive protein, leucocytosis, anaemia, mild thrombocytopaenia, renal impairment, hyperbilirubinaemia and abnormal liver function tests; arterial bl

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Parry, Christopher M., Nguyen Thi Tuyet Hoa, To Song Diep, et al. "Value of a Single-Tube Widal Test in Diagnosis of Typhoid Fever in Vietnam." Journal of Clinical Microbiology 37, no. 9 (1999): 2882–86. http://dx.doi.org/10.1128/jcm.37.9.2882-2886.1999.

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The diagnostic value of an acute-phase single-tube Widal test for suspected typhoid fever was evaluated with 2,000 Vietnamese patients admitted to an infectious disease referral hospital between 1993 and 1998. Test patients had suspected typhoid fever and a blood culture positive for Salmonella typhi (n= 1,400) orSalmonella paratyphi A (n = 45). Control patients had a febrile illness for which another cause was confirmed (malaria [n = 103], dengue [n = 76], or bacteremia due to another microorganism [n = 156] or tetanus (n = 265). An O-agglutinin titer of ≥100 was found in 18% of the febrile c

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Onosakponome, E. O., and M. N. Wogu. "The Role of Sex in Malaria-COVID19 Coinfection and Some Associated Factors in Rivers State, Nigeria." Journal of Parasitology Research 2020 (December 2, 2020): 1–4. http://dx.doi.org/10.1155/2020/8829848.

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Objectives. Data on the coinfection of malaria and COVID-19 is highly limited especially in Africa due to the novel nature of the pandemic COVID-19. Malaria and COVID-19 share striking similarities in their symptoms. A cross-sectional randomized study was conducted to investigate the role of sex in the coinfection of malaria and COVID-19 as well as some associated factors in Rivers State, Nigeria. Methods. Ethical approval was obtained from the Rivers State Health and Ethics Committee before the commencement of this study, and the study was conducted at the COVID-19 Treatment Center Medical La

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Islam, Mohammad Zahidul, Makoto Itoh, S. M. Shamsuzzaman, et al. "Diagnosis of Visceral Leishmaniasis by Enzyme-Linked Immunosorbent Assay Using Urine Samples." Clinical and Vaccine Immunology 9, no. 4 (2002): 789–94. http://dx.doi.org/10.1128/cdli.9.4.789-794.2002.

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ABSTRACT A diagnostic method has been developed to detect anti-Leishmania donovani immunoglobulin G (IgG) in urine by enzyme-linked immunosorbent assay (ELISA). In measuring anti-L. donovani IgG, IgA, and IgM in urine, the method performed best in the detection of IgG. The sensitivity and specificity of the assay were determined with panels of urine samples from 62 visceral leishmaniasis (VL) patients, 59 healthy controls from areas of endemicity, 53 healthy controls from areas of nonendemicity, 59 malaria patients, 13 tuberculosis patients, 23 cutaneous leishmaniasis patients, and 7 patients

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Ghanghoriya, Pawan, Purusharth Srivastava, and Praveen K. Bharti. "Study clinical response and parasite clearance response to Artemisinins in severe malaria in children." International Journal of Contemporary Pediatrics 5, no. 3 (2018): 905. http://dx.doi.org/10.18203/2349-3291.ijcp20181511.

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Background: The research was conducted to study the clinical response and parasite clearance response to Artesunate therapy, in children admitted with severe malaria at a tertiary care centre in Central India.Methods: It is a prospective analytical study. 18 microscopy positive children diagnosed with severe malaria were included. Baseline blood samples collected for microscopy and biochemical tests. All patients were administered standard intravenous Artesunate therapy and were watched every 12 hourly for: 1. Resolution of clinical signs and symptoms. Clinical parameters included level of con

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Gubler, Duane J. "Dengue and Dengue Hemorrhagic Fever." Clinical Microbiology Reviews 11, no. 3 (1998): 480–96. http://dx.doi.org/10.1128/cmr.11.3.480.

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SUMMARY Dengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity (the cocirculation of multiple serotypes), and the emergence of dengue hemorrhagic fever in new geographic regions. In 1998 this mosquito-borne disease is the most important tropical infectious disease after malaria, with an estimated 100 million cases of dengue fever, 500,000 cases of dengue hemorrhagic fever, and 25,000 deaths annually. The reasons for this resurgence

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Barradas, P. F., Z. Neto, T. L. Mateus, et al. "Serological Evidence of Rickettsia Exposure among Patients with Unknown Fever Origin in Angola, 2016-2017." Interdisciplinary Perspectives on Infectious Diseases 2020 (August 24, 2020): 1–5. http://dx.doi.org/10.1155/2020/4905783.

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Spotted fever group Rickettsia (SFGR) is one among the aetiologies that cause fever of unknown origin in Angola. Despite their occurrence, there is little information about its magnitude in this country either because it is misdiagnosed or due to the lack of diagnostic resources. For this purpose, eighty-seven selected malaria- and yellow fever-negative serum specimens collected between February 2016 and March 2017 as part of the National Laboratory of Febrile Syndromes, from patients with fever (≥37.5°C) for at least 4 days and of unknown origin, were screened for Rickettsia antibodies throug

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Obioma, Azuonwu, Ihua Nnnena, and Nwaokorobia Judith. "Invivo Impact of Malaria and HIV Co-Infection on CD4 Cell Count of Infected Patients of Niger Delta Extraction." Journal of Advanced Pharmaceutical Science And Technology 2, no. 2 (2020): 18–25. http://dx.doi.org/10.14302/issn.2328-0182.japst-20-3347.

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The study evaluated the impact of co-infection of malaria parasitaemia, and HIV positive indices on the CD4 cell count of 120 HIV infected subjects, who were already diagnosed and visiting Braithwaite Memorial Specialist Hospital Port Harcourt for routine Medical check-up. Also, a control group of 40 HIV negative were included as part of the study control group. The subjects were between the age ranges of ≤10–79 years respectively. A double check laboratory assay was conducted to detect the presence of antibody to HIV as confirmed using immunocomb 11 and Determine for HIV status. A thick Blood

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Ayieko, Philip, Morris Ogero, Boniface Makone, et al. "Characteristics of admissions and variations in the use of basic investigations, treatments and outcomes in Kenyan hospitals within a new Clinical Information Network." Archives of Disease in Childhood 101, no. 3 (2015): 223–29. http://dx.doi.org/10.1136/archdischild-2015-309269.

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BackgroundLack of detailed information about hospital activities, processes and outcomes hampers planning, performance monitoring and improvement in low-income countries (LIC). Clinical networks offer one means to advance methods for data collection and use, informing wider health system development in time, but are rare in LIC. We report baseline data from a new Clinical Information Network (CIN) in Kenya seeking to promote data-informed improvement and learning.MethodsData from 13 hospitals engaged in the Kenyan CIN between April 2014 and March 2015 were captured from medical and laboratory

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KOTEPUI, Manas, Bhukdee PHUNPHUECH, Nuoil PHIWKLAM, and Kwuntida UTHAISAR. "The Hematological Alteration of Patients Parasitized by Plasmodium vivax." Walailak Journal of Science and Technology (WJST) 15, no. 9 (2017): 637–43. http://dx.doi.org/10.48048/wjst.2018.4592.

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Malaria caused by Plasmodium vivax has placed huge burdens on the health, longevity, and general prosperity of large sections of the human population. In this study, the clinical profiles of patients infected with P. vivax in western Thailand were analyzed. A retrospective cross-sectional study of malaria cases resulting in hospitalization between 2013 and 2015 was collected. Clinical characteristics, diagnoses, and parasitological results on admission, age, and gender were mined from medical records at the laboratory unit, Phop Phra Hospital, located in endemic areas of Tak Province, Thailand

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Cuzzubbo, Andrea J., David W. Vaughn, Ananda Nisalak, et al. "Comparison of PanBio Dengue Duo Enzyme-Linked Immunosorbent Assay (ELISA) and MRL Dengue Fever Virus Immunoglobulin M Capture ELISA for Diagnosis of Dengue Virus Infections in Southeast Asia." Clinical Diagnostic Laboratory Immunology 6, no. 5 (1999): 705–12. http://dx.doi.org/10.1128/cdli.6.5.705-712.1999.

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ABSTRACT The performances of the MRL dengue fever virus immunoglobulin M (IgM) capture enzyme-linked immunosorbent assay (ELISA) and the PanBio Dengue Duo IgM capture and IgG capture ELISA were compared. Eighty sera from patients with dengue virus infections, 24 sera from patients with Japanese encephalitis (JE), and 78 sera from patients with nonflavivirus infections, such as malaria, typhoid, leptospirosis, and scrub typhus, were used. The MRL test showed superior sensitivity for dengue virus infections (94 versus 89%), while the PanBio test showed superior specificity for JE (79 versus 25%)

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Fawas N., Mohammed, Kadeeja Beevi B., Balakrishnan Valliyot, and Sudha Balakrishnan. "Study of acute febrile illness with thrombocytopenia in a tertiary care centre." International Journal of Research in Medical Sciences 6, no. 2 (2018): 455. http://dx.doi.org/10.18203/2320-6012.ijrms20180008.

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Background: In the recent period there is an upsurge in the incidence of fever with thrombocytopenia in the Northern Kerala. This may be due to the several emerging and re emerging infections which causes frequent epidemics in the region. Early diagnosis and meticulous management will prevent fatal out come. Studies on fever with thrombocytopenia are very few in the Northern part of Kerala.Methods: This was a descriptive study conducted at Academy of Medical Sciences Pariyaram over a period of one year from November 2015 to October 2016. The study includes 251 cases attending outpatient and in

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Mirdha, B. R., J. C. Samantaray, and B. Mishra. "Laboratory diagnosis of malaria." Journal of Clinical Pathology 50, no. 4 (1997): 356. http://dx.doi.org/10.1136/jcp.50.4.356-a.

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Choudhury, D. S., and S. K. Ghosh. "Laboratory diagnosis of malaria." Indian Journal of Pediatrics 52, no. 3 (1985): 261–67. http://dx.doi.org/10.1007/bf02754854.

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Kapadia, Maulita P., Panna K. Kamdar, and P. R. Jha. "A study of clinical profile of patients with acute kidney injury in a tertiary care centre." International Journal of Advances in Scientific Research 2, no. 8 (2016): 160. http://dx.doi.org/10.7439/ijasr.v2i8.3511.

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Objectives : The objectives of the study are to study etiology, manifestations and outcome of acute kidney disease.Method : In present study, patients with acute kidney disease admitted to Sir T Hospital, Govt. Medical College Bhavnagar between June 2013 to July 2014 are studied with a detailed history, general physical examination, systemic examination and investigated as per the proforma. Data collected, analysed and the test of significance was calculated by chi square, students t test.Results and conclusion : A prospective study of 100 cases of acute kidney injury admitted to Sir T Hospita

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Moore, B. R., J. M. Benjamin, S. Salman, et al. "Effect of Coadministered Fat on the Tolerability, Safety, and Pharmacokinetic Properties of Dihydroartemisinin-Piperaquine in Papua New Guinean Children with Uncomplicated Malaria." Antimicrobial Agents and Chemotherapy 58, no. 10 (2014): 5784–94. http://dx.doi.org/10.1128/aac.03314-14.

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ABSTRACTCoadministration of dihydroartemisinin-piperaquine (DHA-PQ) with fat may improve bioavailability and antimalarial efficacy, but it might also increase toxicity. There have been no studies of these potential effects in the pediatric age group. The tolerability, safety, efficacy, and pharmacokinetics of DHA-PQ administered with or without 8.5 g fat were investigated in 30 Papua New Guinean children aged 5 to 10 years diagnosed with uncomplicated falciparum malaria. Three daily 2.5:11.5-mg-base/kg doses were given with water (n= 14, group A) or milk (n= 16, group B), with regular clinical

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Reilly, J. T., B. J. Bain, R. Amos, et al. "The laboratory diagnosis of malaria." Clinical & Laboratory Haematology 19, no. 3 (1997): 165–70. http://dx.doi.org/10.1111/j.1365-2257.1997.tb00001.x.

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Reilly, J. T., B. J. Bain, R. Amos, et al. "The laboratory diagnosis of malaria." Clinical and Laboratory Haematology 19, no. 3 (1997): 165–70. http://dx.doi.org/10.1046/j.1365-2257.1997.00062.x.

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