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Journal articles on the topic 'Malaria disease'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Marsh, K. "Malaria-a neglected disease?" Parasitology 104, S1 (1992): S53—S69. http://dx.doi.org/10.1017/s0031182000075247.

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SUMMARYIn situations where malaria eradication is not an option in the foreseeable future the emphasis must be on the control of morbidity and mortality due to malaria. Under such circumstances drawing a distinction between malarial parasitization and malarial disease may be important for workers in both field and laboratory. This concept is explored from the points of view of the epidemiological picture of malaria in endemic populations, the factors which may influence progression to disease and the processes which mediate disease.

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Haldar, Kasturi, and Narla Mohandas. "Malaria, erythrocytic infection, and anemia." Hematology 2009, no. 1 (2009): 87–93. http://dx.doi.org/10.1182/asheducation-2009.1.87.

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Abstract Malaria is a major world health problem. It results from infection of parasites belonging to the genus Plasmodium. Plasmodium falciparum and Plasmodium vivax cause the major human malarias, with P falciparum being the more virulent. During their blood stages of infection, both P falciparum and P vivax induce anemia. Severe malarial anemia caused by P falciparum is responsible for approximately a third of the deaths associated with disease. Malarial anemia appears to be multi-factorial. It involves increased removal of circulating erythrocytes as well as decreased production of erythro

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A., Amsath. "EFFECT OF GLOBAL WARMING AND CLIMATE CHANGES ON VECTOR BORNE DISEASE, MALARIA IN SOME COASTAL DISTRICTS OF TAMIL NADU, INDIA." International Journal of Zoology and Applied Biosciences 1, no. 4 (2016): 186–90. https://doi.org/10.5281/zenodo.1310600.

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Increase global warming and climate changes affect disease transmission by shifting the vector's geographic range and by shortening the pathogen incubation period in the children, the elderly and communities living in poverty. Severe climate sensitive vector-borne diseases are accompanied by increases in the incidence of the disease. The present investigation aimed to investigate regional analysis of malaria in some coastal districts of Tamil Nadu, India. Totally 120 samples were collected from both male and female (age range of 20 to 50 years) of during the period of monsoon (from Septemb

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Gupta, Animesh, and Aishwarya Bhat. "Knowledge, attitude and practices regarding malaria among residents of rural Mangalore, India." International Journal of Research in Medical Sciences 7, no. 1 (2018): 231. http://dx.doi.org/10.18203/2320-6012.ijrms20185386.

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Background: Malaria is one of the most prevalent parasitic diseases worldwide and India has fourth highest number of malaria cases and deaths in the world. Prevention of the disease through better knowledge and awareness is the appropriate way to keep the disease away and remain healthy. Thus, the present study was aimed to assess the knowledge, attitude and practices regarding malaria among residents of Mangalore.Methods: Community based cross sectional study was conducted among residents in Mangalore. The data was collected by using pre-tested semi-structured questionnaire which include soci

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Jahan, Nuzhat, Pragya Shrivastava, and Sakeelur Rahman. "Traditional and Pharmacological Properties of Anti-Malarial Plant Species of Jharkhand, India." Journal of Pharmaceutical Research International 37, no. 6 (2025): 67–78. https://doi.org/10.9734/jpri/2025/v37i67704.

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Malaria is one of the major vector-borne diseases in Jharkhand and other states of India with significant morbidity and mortality. The challenge of drug resistance to anti-malarial medicines has been a major obstacle controlling malarial disease. The National Vector Borne Disease Control Programme has formulated new treatment guidelines for malaria that recommend phytochemical constituent artemisinin based combination therapy as the first-line drugs for P.falciparum malaria. The demand of plant based anti malarial drugs has been increased in the world. Therefore, it is important to find out ef

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Aqeel, Ahmad1 and Sultan Ahmad2*. "A Review: Artemisinin-Based Combination Therapies [ACTs] and K13 Polymorphism." Journal of Biomedical Research & Environmental Sciences 1, no. 4 (2020): 088–09. https://doi.org/10.37871/jels1124.

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Malaria is caused by four plasmodium species in humans (P. falciparum, P. vivax, P. malariae and P. ovale) which spread from one person to another via the bite of female Anopheles mosquito. P. falciparum causes most deaths from malaria [1] and is most prevalent on the African continent whereas P. vivax has a wider geographical distribution [2]. According to the latest WHO estimates, released in December 2015, there were 214 million cases of malaria in 2015 and 438,000 deaths [3]. Existing strategies to control malaria include vector control, chemoprevention and case management [4]. Without a f

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Domintic Kwiatkowski. "Malarial disease and immunity in malaria." Journal of Infection 40, no. 2 (2000): A10. http://dx.doi.org/10.1016/s0163-4453(00)80040-7.

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Dr., Prabhanjan S., S. Kulkarni Swaroop, R. Kundargi Satvik, and Kumar R. Ranjith. "Detection of Malarial Parasites using Deep Learning." International Journal of Innovative Science and Research Technology 8, no. 5 (2023): 28–33. https://doi.org/10.5281/zenodo.7922711.

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Malaria is a fatal disease that leads to the death of lakhs of individuals every year. Malaria is caused by a microbe belonging to the Plasmodium group. Five types of these organisms cause this disease in a foreign body. P. falciparum, P. vivax, P. ovale, and P. malariae are the five varieties of parasites that cause malaria. P. Falciparum infected are the ones who are more susceptible to keywords as others are mildly infectious. Malaria is spread by a mosquito species called anopheles it is the same that spreads dengue too. However, this disease could be cured if detected at early stages. Det

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Hussain, Uzair, Ahmad Ali, Kashif Sultan, Asim Alvi, and Muhammad Waleed Khan. "Malaria Detection using Microscopic Image Analysis: A Convolution Neural Network Based Approach." Pakistan Journal of Engineering and Technology 5, no. 2 (2022): 188–92. http://dx.doi.org/10.51846/vol5iss2pp188-192.

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Malaria is a potentially fatal disease which is caused by Plasmodium parasite. These parasites are transmitted to humans through the bites of female Anopheles mosquitoes which play the role of disease vector. Five types of plasmodium cause malaria named P. Falciparum, P. Vivax, P. Ovale, P. Knowlesi, and P. Malariae, Among the Plasmodium parasites, Falciparum and Vivax are particularly lethal to humans. Therefore, early detection of malaria is mandatory to avoid the loss of human life. Different automatic/semi-automatic malaria detection techniques are available in the literature, which reduce

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Sabbatani, Sergio, Roberto Manfredi, and Sirio Fiorino. "Malaria infection and the anthropological evolution." Saúde e Sociedade 19, no. 1 (2010): 64–83. http://dx.doi.org/10.1590/s0104-12902010000100006.

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During the evolution of the genus Homo, with regard to species habilis, erectus and sapiens, malaria infection played a key biological role, influencing the anthropological development too. Plasmodia causing malaria developed two kinds of evolution, according to a biological and philogenetical point of view. In particular, Plasmodium vivax, Plasmodium malariae, and Plasmodium ovale, would have either coevolved with human mankind (coevolution), or reached human species during the most ancient phases of genus Homo evolution. On the other hand, Plasmodium falciparum has been transmitted to humans

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Tokponnon, Filémon, Razak Osse, Jean Gille Egui, et al. "Determination of Plasmodial Species Prevalence among Patients Received at Cotonou Boni Clinic during Rainy Season in the Year 2022." International Journal of TROPICAL DISEASE & Health 44, no. 16 (2023): 9–15. http://dx.doi.org/10.9734/ijtdh/2023/v44i161464.

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Aims: Malaria is a life-threatening disease caused by parasites transmitted by bites from infected female anopheles. It is a preventable and treatable illness. It remains a recurring disease among public health diseases that exposes many people to a risk of infection, including children under the age of 05 in Benin. Methods: To determine the prevalence of malaria and different plasmodial species at the Dr Pierre BONI Clinic, we performed venous and capillary samples on 731 patients for the realization of thick drops and blood smears between June and July 2022. Results: Three plasmo

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Soma-Pillay, P., and A. P. Macdonald. "Malaria in pregnancy." Obstetric Medicine 5, no. 1 (2012): 2–5. http://dx.doi.org/10.1258/om.2011.110063.

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Malaria is a complex parasitic disease affecting about 32 million pregnancies each year in sub-Saharan Africa. Pregnant women are especially susceptible to malarial infection and have the risk of developing severe disease and birth complications. The target of Millennium Development Goal 6 is to end malaria deaths by 2015. Maternal and perinatal morbidity and mortality due to malaria may be reduced by implementing preventive measures, early diagnosis of suspected cases, effective antimalarial therapy and treatment of complications.

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Murodullayeva, Sarvinoz Oʻtkirbek qizi Murodullayeva Farangiz Oʻtkirbek qizi Ziyayev Farrux Abdusalim oʻgʻli. "MALARIA." INTERNATIONAL BULLETIN OF MEDICAL SCIENCES AND CLINICAL RESEARCH 3, no. 1 (2023): 42–44. https://doi.org/10.5281/zenodo.7550060.

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Malaria is a disease that occurs among people, and it is an acute infectious disease. Several types of malaria are found among the population. This disease is one of the diseases spread among humans by means of flies. 4 types of the disease are more common. Malaria is transmitted to humans by female mosquitoes. This disease develops gradually in the human body. At first, it parasitizes in the liver, then in tissues, and finally in erythrocytes, which are shaped elements of blood.

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Tewari, D. D., L. A. Braimoh, and K. G. Bokana. "Factors Affecting Malaria Epidemics and Its Economic Impacts on Households in Ajegunle, Lagos State, Nigeria." Journal of Interdisciplinary Economics 21, no. 1 (2009): 79–96. http://dx.doi.org/10.1177/02601079x09002100107.

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Malaria is one of the most common and deadly diseases, especially in sub-Saharan and tropical African countries, including Nigeria. Over the years, malaria epidemic affected about 3 million people in Nigeria. The disease does not only affect income or spending of individuals and households but also economic growth of the country. The major objectives of this study are (1) to estimate the costs of malaria to a household living in Ajegunle city, and (2) to build a logistic model which predicts the probability of occurrence of malaria based on a set of variables. One apparent pattern of the cost

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S., D. Dawada, and L. Pawar S. "An Overview On Malarial Parasites And Its Life Cycle." International Journal of Advance and Applied Research S6, no. 18 (2025): 526–28. https://doi.org/10.5281/zenodo.15260364.

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<em>The present article highlights on the malarial parasites and its life cycle. Malaria is an ancient disease. Research has been going on for a century. When an infected Anopheles mosquito bites a person, that person gets malaria. It is the only mosquito that transmits malaria. Malaria is caused by the Anopheles mosquito biting an infected person. Mosquitoes are infected by feeding on the blood of an infected person containing the parasite. When that mosquito bites another person, that person becomes infected with malaria. According to WHO's </em>2022<em> report, the disease caused </em>608,0

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Collins, William E., and Geoffrey M. Jeffery. "Plasmodium malariae: Parasite and Disease." Clinical Microbiology Reviews 20, no. 4 (2007): 579–92. http://dx.doi.org/10.1128/cmr.00027-07.

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SUMMARY A review of the life history of Plasmodium malariae, the quartan malaria parasite of humans, is presented. Much of the information is based on data obtained from induced infections in humans who were given malaria therapy for the treatment of neurosyphilis between 1940 and 1963. Prepatent periods (i.e., the time until the first day of parasite detection) fever episodes, and maximum parasitemias as a result of infection with P. malariae were obtained and are presented. Experimental and known vectors of the parasite are also discussed. Splenectomized chimpanzees and New World monkeys are

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Shaher Banu, S., Muneeb Jehan, and Muhib Jehan. "An analysis of the attitude of Patients towards Laboratory Services for Malaria Disease in Hyderabad India." Open Access Public Health and Health Administration Review 1, no. 1 (2023): 26–39. http://dx.doi.org/10.59644/oapr.1(1).2022.14.

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Malaria is the world's most important parasitic infection, which poses major health challenges. Malaria is a major cause of deaths in the tropical area of the world. Two hundred and nineteen million cases were reported worldwide in 2010. Changes in blood cell counts are a well-known feature of malarial infections. These changes involve major cell lines including red blood cells (RBC), leukocytes and thrombocytes. Human malaria can be caused by any of several species of Plasmodium parasites that occur together in various combinations in regions of endemicity. P. falciparum is responsible for al

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Zhang, De-Liang, Jian Wu, Binal N. Shah, et al. "Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk." Science 359, no. 6383 (2018): 1520–23. http://dx.doi.org/10.1126/science.aal2022.

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Malaria parasites invade red blood cells (RBCs), consume copious amounts of hemoglobin, and severely disrupt iron regulation in humans. Anemia often accompanies malaria disease; however, iron supplementation therapy inexplicably exacerbates malarial infections. Here we found that the iron exporter ferroportin (FPN) was highly abundant in RBCs, and iron supplementation suppressed its activity. Conditional deletion of the Fpn gene in erythroid cells resulted in accumulation of excess intracellular iron, cellular damage, hemolysis, and increased fatality in malaria-infected mice. In humans, a pre

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Lainy, Krisdianto Putra, Geraldo Laurus, and Yosef Samon Sugi. "CASE REPORT: PANCYTOPENIA IN SEVERE MALARIA WITH SUSPECTED HEMOPHAGOCYTIC SYNDROME AT ATAMBUA HOSPITAL." Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) 12, no. 2 (2023): 85–87. http://dx.doi.org/10.14710/dmj.v12i2.36945.

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Background: Malaria is a parasitic infectious disease caused by Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. The signs of a malaria infection include fever, chills, anemia, and splenomegaly. In the Belu district, the incidence of malaria is still high. It’s about 10,6 per 1000 population. Objective: To describe a case of Malaria in one of patient in Indonesia.Methods: Case reportResults: A 61-year-old woman with Malaria with clinical manifestations as follow, fever, body aches, and chills felt since 3 days before hospital admissions. On the 4th day of trea

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Jayaraj, Vivek J., Dhesi Baharaja, Navindran Gopalakrishnan, and Yomain Kaco. "Locally transmitted malaria in Tawau, Sabah, Malaysia." MalariaWorld Journal 8, no. 16 (2017): 1–4. https://doi.org/10.5281/zenodo.10781197.

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<strong>Background.</strong> Tawau was the epicentre of malaria infections in the 1970-1990’s, when industrialisation swept across the state of Sabah, Malaysia. Since then, effective public health intervention, mainly the Malaria Elimination Programme, introduced in 1998, has seen the disease shrivel down into its final elimination phase. Here we retrospectively analyse the case of a 63 year old male with multiple comorbidities who had no exposure to localities with high risk of infection- thus raising the question regarding the means of transmission. <strong>Materials and methods.</stro

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Anwar, Ali Jamali Jawaid Hussain Lighari Ghulam Mustafa Jamali Bhojo Mal Tanwani Ameer Ali Jamali Muhammad Aslam Channa. "MALARIA: PLASMODIUM TYPE DIFFERENCE IN PATIENTS SUFFERING FROM MALARIA." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 09 (2018): 9122–33. https://doi.org/10.5281/zenodo.1435086.

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<strong><em>Background: </em></strong><em>Frequency of malaria infection has been changed in region according to environmental factors and diseases. Plasmodium falciparum and vivax are both common in the areas where malaria is frequent. Studies suggest the management validity according to plasmodium type in disease. </em> <strong><em>Objective: </em></strong><em>The primary goal of study is to find out the plasmodium difference of malaria. </em> <strong><em>Design: </em></strong><em>This study was cross sectional.</em> <strong><em>Setting:</em></strong><em> The current study was performed at m

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Weatherall, David J., Louis H. Miller, Dror I. Baruch, et al. "Malaria and the Red Cell." Hematology 2002, no. 1 (2002): 35–57. http://dx.doi.org/10.1182/asheducation-2002.1.35.

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Abstract Because of the breakdown of malaria control programs, the constant emergence of drug resistant parasites, and, possibly, climatic changes malaria poses a major problem for the developing countries. In addition, because of the speed of international travel it is being seen with increasing frequency as an imported disease in non-tropical countries. This update explores recent information about the pathophysiology of the disease, its protean hematological manifestations, and how carrier frequencies for the common hemoglobin disorders have been maintained by relative resistance to the mal

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Olatunde, Adesola C., Douglas H. Cornwall, Marshall Roedel, and Tracey J. Lamb. "Mouse Models for Unravelling Immunology of Blood Stage Malaria." Vaccines 10, no. 9 (2022): 1525. http://dx.doi.org/10.3390/vaccines10091525.

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Malaria comprises a spectrum of disease syndromes and the immune system is a major participant in malarial disease. This is particularly true in relation to the immune responses elicited against blood stages of Plasmodium-parasites that are responsible for the pathogenesis of infection. Mouse models of malaria are commonly used to dissect the immune mechanisms underlying disease. While no single mouse model of Plasmodium infection completely recapitulates all the features of malaria in humans, collectively the existing models are invaluable for defining the events that lead to the immunopathog

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Bisoffi, Zeno, Federico Gobbi, Dora Buonfrate, and Jef Van den Ende. "DIAGNOSIS OF MALARIA INFECTION WITH OR WITHOUT DISEASE." Mediterranean Journal of Hematology and Infectious Diseases 4, no. 1 (2012): e2012036. http://dx.doi.org/10.4084/mjhid.2012.036.

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The revised W.H.O. guidelines for malaria management in endemic countries recommend that treatment should be reserved to laboratory confirmed cases, both for adults and children. Currently the most widely used tools are rapid diagnostic tests (RDTs), that are accurate and reliable in diagnosing malaria infection. However, an infection is not necessarily a clinical malaria, and RDTs may give positive results in febrile patients who have another cause of fever. Excessive reliance on RDTs may cause overlooking potentially severe non malarial febrile illnesses (NMFI) in these cases. In countries o

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El-Ghitany, Engy Mohamed, Mohamed Abdelsalam Mohamed Abdelmohsen, Azza Galal Farghaly, Ensaf Saied Abd El-Gawwad, and Ekram Wassim Abd El-Wahab. "Knowledge, Attitude, and Practice among Egyptian Travelers: Pre-travel Vaccination and Malaria Prophylaxis." International Journal of Travel Medicine and Global Health 6, no. 3 (2018): 125–36. http://dx.doi.org/10.15171/ijtmgh.2018.23.

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Introduction: More than one third of travelers to developing countries report health problems when traveling. The Egyptian Ministry of Health reports the occurrence of 400 cases of malarial infection yearly among Egyptian travelers. This article aimed to assess the knowledge, attitude, and practice (KAP) of Egyptian travelers towards infectious diseases, vaccination, and malaria chemoprophylaxis. Methods: A survey was conducted at Cairo International Airport and included 1500 travelers. The questionnaire inquired about the travelers’ knowledge about infectious diseases at their destinations an

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Pass, Iyamah, Famuti Ayodeji, and Idu MacDonald. "GC-MS and Molecular Docking Studies for Identification of Anti-malarial Compounds in Agbo-Iba PMII-a Polyherbal Formulation." Chemistry Research Journal 2, no. 1 (2017): 46–56. https://doi.org/10.5281/zenodo.13956928.

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Malaria prevalence is one of the life-threatening diseases responsible for more deaths around the world than any other parasitic disease. Due to the outbreak of strains that show resistance to the current synthetic anti-malarial arsenal, a large focus has been directed to structure based drug designing. The present study investigated the anti-malarial active constituents present in an ethanolic extracted polyherbal formulation (Agbo-iba PMII) comprising Sixteen (16) plants using GC-MS analysis and molecular docking studies of the identified compounds to determine the potential of the polyherba

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Parikh, Harvy, Ravi Shah, Nilesh Doctor, and Hemant Shah. "A study of serum calcium level in cases of malaria in a tertiary care hospital." International Journal of Advances in Medicine 8, no. 12 (2021): 1827. http://dx.doi.org/10.18203/2349-3933.ijam20214518.

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Background: Malaria is a tropical disease caused by Plasmodium species, commonly P. falciparum and P. vivax. Carpopedal spasm has been noted in many patients presenting with malarial fever. Most of the patients are later found to have hypocalcaemia. Hypocalcaemia associated with malaria can cause many clinical manifestations, including life threatening conditions such as arrhythmias, convulsions etc.Methods: A cross-sectional study was conducted with the aim to determine the prevalence and clinical profile of hypocalcaemia in different types of malarial fever. 88 patients of malarial fever wer

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Jain, Priyamvada, Babina Chakma, Sanjukta Patra, and Pranab Goswami. "Potential Biomarkers and Their Applications for Rapid and Reliable Detection of Malaria." BioMed Research International 2014 (2014): 1–20. http://dx.doi.org/10.1155/2014/852645.

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Malaria has been responsible for the highest mortality in most malaria endemic countries. Even after decades of malaria control campaigns, it still persists as a disease of high mortality due to improper diagnosis and rapidly evolving drug resistant malarial parasites. For efficient and economical malaria management, WHO recommends that all malaria suspected patients should receive proper diagnosis before administering drugs. It is thus imperative to develop fast, economical, and accurate techniques for diagnosis of malaria. In this regard an in-depth knowledge on malaria biomarkers is importa

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Marusaha, Ronal Maruli, Dian Noviandri, and Andre Hasudungan Lubis. "The Expert System of Determining the Type of Malaria by using Dempster-Shafer Method." Bulletin of Information Technology (BIT) 4, no. 3 (2023): 377–83. http://dx.doi.org/10.47065/bit.v4i3.887.

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Malaria is the most dominant disease in Asia and Africa and may become a life-threatening disease for it suffers. The types of malaria such as Plasmodium Vivax, Plasmodium Ovale, Plasmodium Malariae, and Plasmodium Falciparum are mostly infected people around the world. These types of malaria have certain symptoms that drives difficulties for some patients to confirm which malaria that their infected. A clinical testing and medical diagnostic assessments may be performed to determine the types of malaria, but utilizing a system also brings some benefits for rural areas which lack of medical fa

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Agarwal, Ajay K., Ghanshyam D. Katiyar, Swati Khan, Bharat C. Chaudhary, Mahendra Sharma, and Dharmendra Kumar. "A cross sectional study of thrombocytopenia in malaria positive cases in a tertiary care hospital of Bareilly." International Journal Of Community Medicine And Public Health 6, no. 12 (2019): 5348. http://dx.doi.org/10.18203/2394-6040.ijcmph20195497.

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Background: To find out correlation of thrombocytopenia with malaria. Malaria is a protozoal disease caused by infection with parasite of genus Plasmodium. Thrombocytopenia is a common and early sign of malarial infection and 60-80% thrombocytopenia is observed in malarial cases and present more frequently and severe in complicated P. falciparum malaria.Methods: A cross sectional study done in Central Pathological Lab of Department of Pathology, RMCH, Bareilly. Blood samples collected in ethylenediaminetetraacetic acid vial and blood smear was examined for malaria parasite within red blood cel

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Vera Akmilia, Anak Agung Ayu Yuli Gayatri, and Anak Agung Wiradewi Lestari. "Cerebral Malaria from a Plasmodium falciparum and Plasmodium malariae Co-Infection: A Case Report on a Diagnostic Challenge." Archives of The Medicine and Case Reports 6, no. 3 (2025): 1448–59. https://doi.org/10.37275/amcr.v6i3.779.

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Severe malaria, primarily caused by Plasmodium falciparum, is a life-threatening medical emergency. Its diagnosis can be significantly complicated by mixed-species infections, where the presence of a less virulent Plasmodium species may mask the true etiological agent of the severe disease, leading to potential delays in appropriate therapy. This report details a case of cerebral malaria where such a diagnostic challenge occurred. An 18-year-old male with a recent travel history to a malaria-endemic area in Indonesia presented with a one-day history of decreased consciousness (Glasgow Coma Sca

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Rawal, Deepak. "An overview of natural history of the human malaria." International Journal of Mosquito Research 7, no. 2 (2020): 8–10. https://doi.org/10.5281/zenodo.7598379.

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Malaria has troubled humans for thousands of years. Disease resembling malaria has been described for more than 5000 years. Malaria is currently endemic in more than 100 tropical and subtropical countries. The etymology of malaria is derived from mal aria means bad air in medieval Italian. This is because ancient Romans thought that malaria came from fumes in the swamps. Over 25 distinct species of Plasmodium are identified for transmission of malaria in primates but only four species of Plasmodium are responsible for human malaria viz. Plasmodium falciparum, Plasmodium ovale, Plasmodium malar

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Djuidje Chatue, Ide Armelle, Maximilienne Ascension Nyegue, Severin Donald Kamdem, et al. "Association between Epstein-Barr virus reactivation and severe malaria in pregnant women living in a malaria-endemic region of Cameroon." PLOS Global Public Health 4, no. 8 (2024): e0003556. http://dx.doi.org/10.1371/journal.pgph.0003556.

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Malaria kills nearly 619,000 people each year. Despite the natural immunity acquired to malaria, pregnant women and children under five die from severe forms of the disease in sub-Saharan Africa. Co-infection with acute Epstein-Barr Virus (EBV) infection has been shown to suppress the anti-malarial humoral responses, but little is known about the impact of EBV reactivation on malaria-associated morbidity. This study investigated the association between EBV reactivation and malaria severity in pregnant women living in a malaria-endemic region in Cameroon. A cross-sectional study was conducted o

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Lema, S. Y., K. Abdullahi, M. A. Yahaya, J. Ibrahim, J. Suleiman, and M. Hashimu. "Evaluation of malaria parasites in relation to Blood Groups among participants attending tertiary health facility, Sokoto State, Nigeria." Nigerian Journal of Parasitology 42, no. 2 (2021): 251–57. http://dx.doi.org/10.4314/njpar.v42i2.9.

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Malaria is still considered a major public health problem and a leading cause of morbidity and mortality in developing countries of the world especially Africa, which Nigeria is among. Studies were conducted to evaluate malaria parasites in blood group of 440 consented participants in Sokoto Specialist Hospital. Blood samples were collected from each of the participants, and examined parasitologically using the thick and thin blood techniques. Overall 69.09 percent of malaria prevalence was recorded. It was statistically observed to be higher but insignificant in males (71.43%) than in females

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Siagian, Forman E. "A literature study of anemia among malaria cases reported in Indonesia, from west to east: a parasito-epidemiology perspective." International Journal Of Community Medicine And Public Health 7, no. 10 (2020): 4135. http://dx.doi.org/10.18203/2394-6040.ijcmph20203966.

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Severe malarial anemia (SMA) is a potentially fatal complication of malaria, a neglected parasitic tropical disease that still become a global health problem. It occurs predominantly in vulnerable groups in the community, especially children and pregnant women living in endemic areas, including Indonesia. The data on prevalence of SMA and its contributing factors are sparse and incomplete, so the aim of this simple literature study is to provide that data. The author doing the electronic literature searching on Indonesia’s data concerning malaria related anemia and factors that might contribut

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Oganyan, R. B., I. V. Roganova, A. V. Lyubushkina, G. R. Davlekamova, D. Yu Konstantinov, and V. A. Nikonorov. "Features of severe course of tropical malaria with secondary diseases caused by Klebsiella pneumonia (clinical case)." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 14, no. 6 (2024): 117–23. https://doi.org/10.20340/vmi-rvz.2024.6.case.3.

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Relevance. Imported malaria cases in the Russian Federation are detected annually. In the absence or delayed treatment it can lead to patients´ complications and death. The aim of the work is to present and analyze a fatal tropical malaria clinical case with secondary diseases caused by Klebsiella pneumoniae. Materials and methods. The work was carried out on the basis of the clinic and the Department of Infectious Diseases with Epidemiology of Samara State Medical University. A clinical case of tropical malaria severe course in a patient on the 18th disease day admitted in a malarial algid st

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Chavan, Vishwajeet Manohar, Girish Manohar Chavan, and Aaluri Uma. "A systematic self-study and analysis in prevalence of malaria across the world." Panacea Journal of Medical Sciences 13, no. 1 (2023): 3–8. http://dx.doi.org/10.18231/j.pjms.2023.002.

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Malaria is a febrile mosquito borne infectious disease which is caused by plasmodium. Malaria is one of the most deadliest and serious tropical disease ever witnessed by humanity. There are five species of plasmodium which are reported to infect humans. Out of the five species plasmodium falciparum has been reported to be the most deadliest form of plasmodium.A systemic self-study was planned to analyze and study the current prevalence of malaria globally. With the application of electronic databases we searched PubMed, Google Scholar, Web of Science, WHO website, Medline Plus, Health line &am

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Pikatan, Orlando, Ellen Ferlita Tirtana, Kezia Seraphine, and Wienta Diarsvitri. "BIOMARKERS AND PROGNOSTIC SCORING IN CEREBRAL MALARIA." MNJ (Malang Neurology Journal) 8, no. 2 (2022): 140–43. http://dx.doi.org/10.21776/ub.mnj.2022.008.02.13.

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Malaria remains a public health concern and remain the deadliest in infectious disease in the world. Cerebral malaria is a particularly severe complication of this disease and associated with high mortality. This literature review is made up from 19 literatures consisting of journals, and book. The literature review used data base www.pubmed.com, and www.scholar.google.com using “cerebral malaria and biomarker, predictor of cerebral malaria and treatment of severe malaria”. The languages for this journal are English and Indonesian. From the collection of literatures in this literature review,

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Ashraf, Shoaib, Areeba Khalid, Arend L. de Vos, Yanfang Feng, Petra Rohrbach, and Tayyaba Hasan. "Malaria Detection Accelerated: Combing a High-Throughput NanoZoomer Platform with a ParasiteMacro Algorithm." Pathogens 11, no. 10 (2022): 1182. http://dx.doi.org/10.3390/pathogens11101182.

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Eradication of malaria, a mosquito-borne parasitic disease that hijacks human red blood cells, is a global priority. Microscopy remains the gold standard hallmark for diagnosis and estimation of parasitemia for malaria, to date. However, this approach is time-consuming and requires much expertise especially in malaria-endemic countries or in areas with low-density malaria infection. Thus, there is a need for accurate malaria diagnosis/parasitemia estimation with standardized, fast, and more reliable methods. To this end, we performed a proof-of-concept study using the automated imaging (NanoZo

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ALIFRANGIS, M., M. M. LEMNGE, R. MOON, et al. "IgG reactivities against recombinant Rhoptry-Associated Protein-1 (rRAP-1) are associated with mixed Plasmodium infections and protection against disease in Tanzanian children." Parasitology 119, no. 4 (1999): 337–42. http://dx.doi.org/10.1017/s0031182099004825.

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A cross-sectional sero-epidemiological study was performed in Magoda, Tanzania, an area where malaria is holoendemic. Blood samples were collected from children (1–4 years) and tested for IgG antibody reactivity against 2 recombinant protein fragments of Plasmodium falciparum Rhoptry-Associated Protein-1 (rRAP-1). The data were related to the prevalence of malarial disease and single P. falciparum or mixed Plasmodium infections. Fever ([ges ]37·5 °C) in combination with parasite densities >5000/μl were used to distinguish between children with asymptomatic malaria infections and those with

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Haldar, Tapas. "MALARIA: BIOLOGY, DISEASE AND CONTROL-A COMPREHENSIVE OVERVIEW." International Journal of Advanced Research 13, no. 05 (2025): 451–56. https://doi.org/10.21474/ijar01/20920.

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Malaria is an infectious disease caused by Plasmodium parasites, which are spread to humans through the bites of infected female Anopheles mosquitoes. Despite ongoing control efforts, it remains a severe public health threat-particularly in sub-Saharan Africa, where children under five face the highest risk of infection and mortality due to limited access to healthcare. Once in the human host, parasites undergo liver-stage development followed by asexual replication in RBCs, leading to symptoms such as fever, chills, and anaemia. Severe Plasmodium falciparum infection can result in cytoadhesio

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AR, Carnemolla, and Benton AH. "Understanding disease pathogenesis and host response of endemic malaria in previously exposed individuals compared to naïve individuals." Journal of Medical and Scientific Research 11, no. 3 (2023): 235–40. http://dx.doi.org/10.17727/jmsr.2023/11-43.

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Plasmodium falciparum and Plasmodium vivax are two major species of malaria that can establish a focus of infection in millions of individuals per year. Principally, this occurs in the tropical and subtropical regions of the world where malaria is endemic due to the ubiquity of the disease vector, the Anopheles mosquitos. Malaria takes the lives of thousands of infected individuals as the progression of disease symptoms having fatal consequences. This disease mainly affects children and pregnant women which poses a great public health concern. It is also a global economic burden from the milli

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Al-Awadhi, Mohammad, Suhail Ahmad, and Jamshaid Iqbal. "Current Status and the Epidemiology of Malaria in the Middle East Region and Beyond." Microorganisms 9, no. 2 (2021): 338. http://dx.doi.org/10.3390/microorganisms9020338.

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Vector-borne parasitic infectious diseases are important causes of morbidity and mortality globally. Malaria is one of the most common vector-borne parasitic infection and is caused by five Plasmodium species, namely P. falciparum, P. vivax, P. ovale, P. malariae, and P. knowlesi. Epidemiologically, differences in the patterns of malaria cases, causative agent, disease severity, antimicrobial resistance, and mortality exist across diverse geographical regions. The world witnessed 229 million malaria cases which resulted in 409,000 deaths in 2019 alone. Although malaria cases are reported from

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Priambodo, Doni, Mahendra Septadi, Yugata Halimawan, and Dhite Nugroho. "Transfusion-transmitted Malaria in a Pregnant Woman with Beta Thalassemia Minor: A Case Report." Open Access Macedonian Journal of Medical Sciences 11, no. C (2023): 50–52. http://dx.doi.org/10.3889/oamjms.2023.10755.

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BACKGROUND: Malaria is an infectious disease that is caused by plasmodium parasites. Malaria is commonly spread by female anopheles mosquitoes carrying the plasmodium parasite, although it can also be transferred through blood transfusion. In the developing world, malaria frequently affects the most vulnerable, including small children and pregnant women, resulting in severe morbidity and mortality. CASE PRESENTATION: This case report presents a primigravida with beta-thalassemia who developed malaria during her pregnancy despite never having visited a malaria-endemic region. A 22-year-old pri

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Inyama, P. U., I. C. J. Omalu, S. S. Eke, P. Okoro, and K. Adeniyi. "Sero-prevalence of Plasmodium falciparum and Plasmodium malariae among HIV-positive patients in Jos, Plateau State, North-central Nigeria." Journal of Public Health and Diseases 3, no. 3 (2020): 66–71. http://dx.doi.org/10.31248/jphd2020.069.

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Malaria is a leading cause of disease burden in Nigeria, although surprisingly few contemporary, age-stratified data exist on malaria epidemiology in the country. Transmission of Plasmodium falciparum and P. Malariae among HIV –infected individuals was studied in Jos, Central Nigeria to ascertain the prevalence of malaria and HIV infection with a specific focus on how risk factors differ between demographic groups. Blood samples were collected from individuals by venepuncture in 5 ml vacutainers and tubes containing Ethylene diamine tetra acetic acid (EDTA). Thick and thin blood smears were ma

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Sousa, Arturo, Mónica Aguilar-Alba, Mark Vetter, Leoncio García-Barrón, and Julia Morales. "Spatiotemporal Distribution of Malaria in Spain in a Global Change Context." Atmosphere 11, no. 4 (2020): 346. http://dx.doi.org/10.3390/atmos11040346.

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Malaria is one of the most cited vector-borne infectious diseases by climate change expert panels. Malaria vectors often need water sheets or wetlands to complete the disease life cycle. The current context of population mobility and global change requires detailed monitoring and surveillance of malaria in all countries. This study analysed the spatiotemporal distribution of death and illness cases caused by autochthonous and imported malaria in Spain during the 20th and 21st centuries using multidisciplinary sources, Geographic Information System (GIS) and geovisualisation. The results obtain

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Laouali, Salissou, Koudoukpo Christiane, Zaki Harouna, Brah M. Souleymane, and Nouhou Hassan. "A Case Of Intermediate Toxic Epidermal Necrolysis (Lyell Syndrome) Induced By Hydroxychloroquine Sulfate: A Report." European Scientific Journal, ESJ 12, no. 12 (2016): 90. http://dx.doi.org/10.19044/esj.2016.v12n12p90.

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Malaria is a parasite disease that is endemic in tropical country as Niger (West Africa). Hydroxychloroquine sulfate (HCQ) is a synthetic antimalarial drug that is very often used to treat connective tissue diseases such as, scleroderma, systemic or discoid lupus erythematosus, rheumatoid arthritis. This drug may induce numerous cutaneous adverse reactions as well as the other anti-malarial drugs. We report on a case of intermediate Lyell syndrome that occurred in the first week of treatment of malaria attack with a young woman, aged 19, following the administration of hydroxychloroquine sulfa

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Lamb, Tracey J., Douglas E. Brown, Alexandre J. Potocnik, and Jean Langhorne. "Insights into the immunopathogenesis of malaria using mouse models." Expert Reviews in Molecular Medicine 8, no. 6 (2006): 1–22. http://dx.doi.org/10.1017/s1462399406010581.

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Malaria kills approximately 1–2 million people every year, mostly in sub-Saharan Africa and in Asia. These deaths are at the most severe end of a scale of pathologies affecting approximately 500 million people per year. Much of the pathogenesis of malaria is caused by inappropriate or excessive immune responses mounted by the body to eliminate malaria parasites. In this review, we examine the evidence that immunopathology is responsible for malaria disease in the context of what we have learnt from animal models of malaria. In particular, we look in detail at the processes involved in endothel

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Mukry, Samina Naz, Madiha Saud, Gul Sufaida, Kashif Shaikh, Arshi Naz, and Tahir Sultan Shamsi. "Laboratory Diagnosis of Malaria: Comparison of Manual and Automated Diagnostic Tests." Canadian Journal of Infectious Diseases and Medical Microbiology 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/9286392.

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Malaria is the second most prevalent disease in Pakistan resulting in ~30,000 annual deaths. In endemic countries like Pakistan precise and timely diagnosis of malaria is imperative to overcome the associated risks of fatal outcomes. Malarial parasite was screened in 128 malaria suspected patients and 150 healthy controls, by species-specific PCR, microscopy of blood smears, hemoanalyzer Sysmex XE-2100, and rapid test devices (First Response Malaria® and ICT Malaria Combo®). The microscopy detected MP in 126 samples (parasite load/µl 386–53712/µl); 71.094% were infected withPlasmodium vivaxand

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K, Affan. "Cost of Illness of Malaria in Coastal Karnataka, India." Journal of Communicable Diseases 53, no. 02 (2021): 28–34. http://dx.doi.org/10.24321/0019.5138.202122.

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Background: Malaria is one of the major health issues in developing and underdeveloped countries. It is considered to be one of the main reasons for morbidity and mortality. This study intends to estimate the cost of illness of malaria at the household level and health service utilisation pattern for malaria treatment in coastal Karnataka. Materials and Methods: It was a secondary data-based cross-sectional study comprising people suffering from malaria during the period from September to December 2016. Result: The median gross total cost of illness (a single episode of malaria) was 4,000 INR,

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