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1

Adedoja, Ayodele, Shola Kola Babatunde, Bukola Deborah Tijani, Ajibola A. Akanbi II, and Olusola Ojurongbe. "Usefulness of Polymerase Chain Reaction in the diagnosis of asymptomatic malaria among school age children in Ilorin, Nigeria." Pan African Journal of Life Sciences 1, no. 1 (2018): 39–45. http://dx.doi.org/10.36108/pajols/8102/10(0170).

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Introduction: In Nigeria, microscopy and Rapid Diagnostic Tests (RDTs) are majorly used routinely to diagnose malaria in clinical settings. In recent years, molecular diagnosis has emerged as the most sensitive method for malaria diagnosis. This study determined the usefulness of Polymerase Chain Reaction (PCR) in comparison to microscopy (Giemsa stained thick and thin smears) for the diagnosis of asymptomatic malaria in Ilorin, Nigeria. Methods: Th e study enrolled 310 school children aged 4–15 years with no sign or symptoms of malaria. Blood samples were collected for identification of Plasm
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2

Ologe, Olufunmilayo M., Olugbenga A. Mokuolu, and Olanrewaju T. Adedoyin. "Pattern of antimalarial prescriptions for children and pregnant mothers by private medical practitioners in Ilorin, Nigeria." Tropical Doctor 37, no. 4 (2007): 212–14. http://dx.doi.org/10.1258/004947507782332946.

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A survey of the prescription practices of private medical practitioners (PMPs) in four local government areas in Kwara State, Nigeria, was carried out using a self-administered pre-tested questionnaire. A total of 49 respondents from 40 private health facilities participated in the survey. The prescription practice of a significant number of PMPs was not in conformity with the National Malarial Treatment policy. There was inadequate knowledge of the classification of malaria; hence, many of the respondents could not recognize severe malaria. Regular continuing medical education and distributio
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Dada, Oladipo A., and Folashade O. Omokhodion. "Home management of malaria by mothers of children under-five in Abeokuta, Southwest Nigeria." Tropical Doctor 37, no. 4 (2007): 217–19. http://dx.doi.org/10.1258/004947507782332982.

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This study reported mothers' practices of home management of malaria in their children aged 0-5 years and highlighted the differences between home management of children with complicated malaria and those with uncomplicated malaria. Of the 380 children seen in the study, 112 (29.5%) had complicated malaria. Complicated malaria was associated with the increasing number of days before presentation at a health facility and delay in the use of antimalarials.
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OKEKE, THEODORA A. "IMPROVING MALARIA RECOGNITION, TREATMENT AND REFERRAL PRACTICES BY TRAINING CARETAKERS IN RURAL NIGERIA." Journal of Biosocial Science 42, no. 3 (2009): 325–39. http://dx.doi.org/10.1017/s0021932009990484.

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SummaryA caretaker training programme was carried out in Ugwuogo-Nike, a rural area in south-east Nigeria, based on formative research within the community. A training of trainers workshop was organized for 30 leaders of women groups who subsequently trained other mothers in their group. Community information activities, which lasted for a period of eight months, included the use of posters, drama group and jingles. The programme was evaluated using the quantitative and qualitative methods that were employed at baseline, which included community survey and focus group discussions (FGDs). For t
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5

Funwei, Roland I. "Age-Dependent Prevalence of Malaria in Akeddei Community in South-South Nigeria." Pan African Journal of Life Sciences 5, no. 2 (2021): 257–62. http://dx.doi.org/10.36108/pajols/1202.50.0230.

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Background: Malaria is highly endemic in Nigeria, making malaria morbidity and mortality a leading public health challenge. The most at risk population of malaria attack is under-five years’ children. However, malaria is presumptively treated in older age groups. This study aimed to determine the age-dependent prevalence of malaria amongst three age groups in a rural community in south-south Nigeria. Methods: A community-based cross-sectional survey comprising febrile and afebrile participants (n = 300) were randomly selected and included for the study. The study participants were grouped into
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6

Oyeyemi, Oyetunde T., Kehinde M. Akinseye, Iyanuoluwa I. Odewuyi, et al. "Malaria and Insecticide-Treated Net (ITN) Utilization among Orphans and Vulnerable Children in Nigeria." Journal of Interdisciplinary Medicine 6, no. 2 (2021): 87–91. http://dx.doi.org/10.2478/jim-2021-0012.

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Abstract Background: The lack of empirical data on the malaria status of orphans and vulnerable children (OVC), access to long-lasting insecticide-treated nets (LLINs), and knowledge about the disease can hamper the development of effective policies and programs to address their malaria-related needs. Aim: The aim of this study was to evaluate knowledge of malaria transmission and utilization of LLINs among OVC in Ondo metropolis, Nigeria. Materials and Methods: A cross-sectional study was conducted in Ondo City, Ondo State, Nigeria, between January and March 2018. The study was carried out am
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7

Udoh, Ekong E., Angela E. Oyo-ita, Friday A. Odey, et al. "Malariometric Indices among Nigerian Children in a Rural Setting." Malaria Research and Treatment 2013 (February 28, 2013): 1–4. http://dx.doi.org/10.1155/2013/716805.

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Malaria contributes to high childhood morbidity and mortality in Nigeria. To determine its endemicity in a rural farming community in the south-south of Nigeria, the following malariometric indices, namely, malaria parasitaemia, spleen rates, and anaemia were evaluated in children aged 2–10 years. This was a descriptive cross-sectional survey among school-age children residing in a rubber plantation settlement. The children were selected from six primary schools using a multistaged stratified cluster sampling technique. They were all examined for pallor, enlarged spleen, or liver among other c
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8

Oladosu, Oladipo O., and Wellington A. Oyibo. "Overdiagnosis and Overtreatment of Malaria in Children That Presented with Fever in Lagos, Nigeria." ISRN Infectious Diseases 2013 (July 19, 2013): 1–6. http://dx.doi.org/10.5402/2013/914675.

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Background. Malaria diagnosis has been largely done clinically. The implication is the likely overdiagnosis of malaria when diagnosis is done soley on the basis of symptoms. Methods. Parasitological diagnosis was done among 1211, 0–12 years old febrile children that attended a Primary Health Centre in Lagos, Nigeria, who were diagnosed clinically and treated based on symptoms. Results. A total of 251 of 1,211 (20.7%) children less than 12 years old and 174 of the 1,027 of children 0–≤5 yrs (16.9%) were slide positive while 853 (83.1%) of 0–≤5 yrs that were slide negative were treated with Arte
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9

Odoko, Joseph O., Ezekiel U. Nwose, Samuel D. Nwajei, Emmanuel A. Agege, John E. Moyegbone, and Eunice O. Igumbor. "Epidemiology of malaria as it relates to utilization of insecticide treated nets among pregnant women and under five years children in South-South Nigeria." International Journal Of Community Medicine And Public Health 7, no. 10 (2020): 4157. http://dx.doi.org/10.18203/2394-6040.ijcmph20204390.

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Pregnant mothers and children under five years are exposed to malaria infection. One of the WHO recommendations on prevention of malaria is the use of insecticide treated nets (ITNs). The use of ITNs is still low in Nigeria. Is to access challenges and improvement on use of ITNs among pregnant mothers and care givers of children under five in Bayelsa, Delta and Rivers state respectively. Review of articles related to use of ITNs among pregnant mothers and under five years children were adopted using The American Journal of Human Genetics among 28 studies. Malaria is responsible for 30% childho
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10

Iwelunmor, Juliet, Collins O. Airhihenbuwa, Gary King, and Ayoade Adedokun. "Contextualizing Child Malaria Diagnosis and Treatment Practices at an Outpatient Clinic in Southwest Nigeria: A Qualitative Study." ISRN Infectious Diseases 2013 (September 24, 2013): 1–6. http://dx.doi.org/10.5402/2013/101423.

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Background. This study sought to explore contextual features of an outpatient clinic located in southwest Nigeria that enable and/or discourage effective diagnosis and treatment of child malaria. Methods. We conducted in-depth interviews with mothers of 135 febrile children attending a pediatric outpatient clinic in southwest Nigeria. Also, participant observations and informal discussions with physicians were conducted to examine the potential impact of context on effective child malaria diagnosis and treatment. Results. The findings indicate that availability of drugs and laboratory testing
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11

Sa'idu, H. I., G. P. Shiaka, and J. B. Balogun. "PREVALENCE AND PATTERN OF SEVERE MALARIA AMONG CHILDREN IN TWO GENERAL HOSPITALS, JIGAWA STATE- NIGERIA." FUDMA JOURNAL OF SCIENCES 5, no. 2 (2021): 511–18. http://dx.doi.org/10.33003/fjs-2021-0502-664.

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The prevalence and pattern of presentation of severe malaria differ from one area to another, in one age group and gender. A descriptive cross sectional study of children between the ages of one month and fourteen years with symptoms of severe malaria was conducted between July and December 2018 in Dutse and Birnin Kudu Local Government Area of Jigawa State. Venous blood samples were used for parasitological, hematological and biochemical examination following standard procedures. Thick and thin blood films were prepared, stained and examined at x100 magnification. A total of 172 children were
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Ademowo, George, Olawunmi Rabiu, Ganiyu Arinola, and Catherine O. Falade. "PO 8571 CYTOKINE PROFILE IN ASYMPTOMATIC SCHOOL CHILDREN CO-INFECTED WITH HELMINTHS AND PLASMODIUM FALCIPARUM IN IBADAN, SOUTH-WEST NIGERIA." BMJ Global Health 4, Suppl 3 (2019): A55.2—A55. http://dx.doi.org/10.1136/bmjgh-2019-edc.145.

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BackgroundIntestinal helminths and malaria are among the most prevalent infectious diseases in the tropics. The effect of co-infections on immune response is not clearly understood. We therefore investigated the immune response profile in children with and without symptoms.MethodsA total of 78 afebrile school children (20 helminth/malaria-co-infected, 17 helminth-infected, 19 malaria-infected and 22 uninfected) and 75 febrile children (14 helminth/malaria-co-infected, 16 helminth-infected, 20 malaria-infected and 25 uninfected) were recruited into the study. Helminths were screened using Kato
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13

Singh, Sanjay, Rupashree Singh, TomD Thacher, NmaM Jiya, and AboiJ K. Madaki. "Predictors of malaria in febrile children in Sokoto, Nigeria." Nigerian Medical Journal 55, no. 6 (2014): 480. http://dx.doi.org/10.4103/0300-1652.144701.

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14

Amodu, Olukemi, Binal N. Shah, Subulade Ademola, Bamidele Tayo, and Victor R. Gordeuk. "Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children." Blood 134, Supplement_1 (2019): 942. http://dx.doi.org/10.1182/blood-2019-132190.

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Host genetic factors that influence the outcome of Plasmodium falciparum malaria infection are not fully understood. These include alpha-thalassemia, sickle cell disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency and cytochrome b5 reductase 3 (CYB5R3) T117S and ferroportin Q248H polymorphisms. G6PD, an X-linked gene, encodes the sole enzyme in red blood cells that produces NADPH for protection from reactive oxygen species. Hemi- or homozygosity for G6PD A+ (G6PD c. 376G) is an African specific polymorphism with reduced activity (PMID:26633385) but no apparent phenotype; hemi- or homo
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15

Sangowawa, Adesola O., Olukemi K. Amodu, Subulade A. Olaniyan, Folakemi A. Amodu, Peter E. Olumese, and Olayemi O. Omotade. "Factors Associated with a Poor Treatment Outcome among Children Treated for Malaria in Ibadan, Southwest Nigeria." Epidemiology Research International 2014 (February 26, 2014): 1–7. http://dx.doi.org/10.1155/2014/974693.

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We present data on factors associated with poor treatment outcome (death or recovery with a neurological complication) among children treated for malaria in Ibadan, Nigeria. A total of 2468 children (1532 with uncomplicated and 936 with severe malaria) were recruited from three government facilities. History was obtained from caregivers and malarial parasite test was carried out on each child. About 76.0% of caregivers had instituted home treatment. Following treatment, 2207 (89.5%) children recovered without complications, 9.1% recovered with neurological complications, and 1.4% died. The pos
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16

Aregbeshola, Bolaji Samson, and Samina Mohsin Khan. "Impact of health facilities on malaria control interventions among children under five years of age and pregnant women in Nigeria." South East Asia Journal of Public Health 7, no. 1 (2017): 35–41. http://dx.doi.org/10.3329/seajph.v7i1.34677.

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Malaria is still one of the biggest public health problems in Nigeria in spite of numerous control interventions against the disease as well as access to and availability of medicines to address it. The children under five years of age and pregnant women are household members that are most at risk of this disease. The study aims to examine the impact of health facilities on malaria control interventions. Secondary data from Nigeria Demographic and Health Survey 2013 was utilized to investigate the impact of type of health facility visited on malaria control interventions. Variables on malaria
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I., Jalo, Isaac E. Warnow, Aliu R., and Hassan K. Shina. "Burden, clinical manifestation and outcome of severe malaria in children at a tertiary hospital in Northeast, Nigeria." International Journal of Contemporary Pediatrics 7, no. 8 (2020): 1659. http://dx.doi.org/10.18203/2349-3291.ijcp20203158.

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Background: Severe malaria is a life-threatening medical emergency and requires prompt and effective treatment to prevent death. The presentation of severe malaria varies depending on such factors as country, age, immunity, socioeconomic factors, drug resistance and type of intervention measures used. The aim of this study is to document the burden and forms of severe malaria in children in this region. Objective of this study was to determine the prevalence, clinical manifestation and outcome of children with severe malaria in Federal Teaching Hospital, GombeMethods: Case notes of patients ad
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18

Ishaku, Nassai, I. Z. Kunihya, J. B. Seni, L. D. Justine, and A. Sarki. "IMPACT OF PREVENTIVE PRACTICES ON ANAEMIA DUE TO MALARIA AMONG CHILDREN ATTENDING OUT-PATIENT CLINIC IN SPECIALIST HOSPITAL YOLA, ADAMAWA STATE, NIGERIA." FUDMA JOURNAL OF SCIENCES 4, no. 2 (2020): 29–33. http://dx.doi.org/10.33003/fjs-2020-0402-202.

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The study focused on the impact of preventive practices on anaemia due to malaria among children. The study considered Out-Patients children who came to laboratory for malaria diagnostic test. Blood sample was examined using Giemsa stain for parasite detection and speciation. Informed consent was obtained and structured questionnaire were administered. Pack Cell Volume was used to screened for anaemia. A total of 310 children were sampled. Malaria anaemia in relation to types of net used, children that were anaemic with malaria used damage insecticide nets recorded highest and least among thos
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Umegbolu, Emmanuel I., and Chinedu N. Madukwe. "Rapid diagnostic test versus microscopy in the diagnosis of acute malaria in a district hospital in Enugu state, Southeast Nigeria." International Journal Of Community Medicine And Public Health 5, no. 1 (2017): 54. http://dx.doi.org/10.18203/2394-6040.ijcmph20175762.

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Background: Malaria is a systemic disease caused by various species of Plasmodium, transmitted through the bite of a female Anopheles mosquito. According to the World Health Organisation, there were 214 million cases of malaria worldwide in 2015. Nigeria’s burden of malaria is about 51million cases and 207,000 deaths annually, accounting for 60% of outpatient visits to hospitals, 11% of maternal mortality, and 30% of child mortality. The study aimed to compare RDT and microscopy in malaria diagnosis in a District Hospital in Enugu state, Southeast Nigeria. Methods: Blood samples of 300 suspect
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Oladimeji, Kelechi Elizabeth, Joyce Mahlako Tsoka-Gwegweni, Santhanalakshmi Gengiah, Amrita Daftary, and Kogieleum Naidoo. "Barriers to effective uptake of malaria prevention interventions in Ibadan, South West Nigeria: a qualitative study." International Journal Of Community Medicine And Public Health 5, no. 4 (2018): 1304. http://dx.doi.org/10.18203/2394-6040.ijcmph20181066.

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Background: Although control measures have achieved considerable success, malaria is still a major public health problem in Nigeria and sub-Saharan Africa. The malaria burden is more among vulnerable groups like pregnant women and under-five aged children. This study explored barriers affecting uptake of current malaria prevention interventions in Ibadan, Southwest Nigeria.Methods: The study was conducted using qualitative research methods between May and August 2016 among community residents in Ibadan, Oyo state-Nigeria. Six focus group discussions (FGDs) and 16 in-depth interviews (IDI) were
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Abhulimhen-Iyoha, Blessing Imuetinyan, and Yetunde Tinuola Israel-Aina. "Socioeconomic and cultural factors associated with mortality in Malaria induced anaemia among under-five children in Benin city, Nigeria." Bangladesh Journal of Medical Science 14, no. 1 (2014): 32–38. http://dx.doi.org/10.3329/bjms.v14i1.17274.

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Background: Children under the age of five years bear the brunt of malaria infection. Malaria induced anaemia (MIA) is the most prevalent presentation of malaria and a major cause of morbidity and mortality in Nigeria. Objective: To determine the socioeconomic and cultural factors associated with mortality in under-five children presenting with malaria induced anaemia. Methods: This is a cross-sectional descriptive study conducted at the Children Emergency Room of the University of Benin Teaching Hospital, Benin City, Nigeria. Questionnaires which were researcher-administered were used to coll
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Azuogu, V., C. Ndie, C. Onah, C. Akpa, N. Eze, and B. Azuogu. "Knowledge and Practice of Malaria Control Measures among Women Attending Antenatal Clinics in Abakaliki, Nigeria." Journal of Epidemiological Society of Nigeria 4, no. 1 (2021): 63–74. http://dx.doi.org/10.46912/jeson.41.

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Background: Pregnant women, children and immune-compromised persons are highly vulnerable to malaria morbidity and mortality. Malaria accounts for about 50% of all clinic attendance in Nigeria and contributes significantly to anaemia in pregnancy, low birth weight, preterm births, still births and perinatal mortality. It is therefore imperative that these highly susceptible groups of people are adequately informed and supported for prevention of malaria at all times. This study assessed the knowledge and practice of malaria control measures among Antenatal Care attendees in Abakaliki.
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SIMON-OKE, Iyabo Adepeju. "Prevalence of Malaria Parasites among Pregnant Women and Children under Five years in Ekiti State, Southwest Nigeria." Journal of Biomedicine and Translational Research 5, no. 1 (2019): 5. http://dx.doi.org/10.14710/jbtr.v5i1.3711.

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Background: Malaria is a deadly disease causing serious public health issues among pregnant women and children worldwide especially in tropical and subtropical Africa. This study was carried out to determine the prevalence of malaria parasites among pregnant women and children under five years in Ekiti State, Nigeria.Methodology: A total of 380 blood samples were collected from the pregnant women and children under five years respectively. Malaria parasites were examined microscopically on thick and thin blood smear stained with Giemsa stain while personal data were collected through questionn
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Anjorin, Abdul-Azeez Adeyemi, Shola Rachael Babalola, and Oluwaseun Paul Iyiade. "Influenza, malaria parasitemia, and typhoid fever coinfection in children: Seroepidemiological investigation in four Health-care Centers in Lagos, Nigeria." Journal of the Pan African Thoracic Society 1 (September 27, 2020): 26–34. http://dx.doi.org/10.25259/jpats_2_2020.

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Objectives: There are similarities in the presentation of influenza-A infection, malaria, and typhoid fever which include their overlapping clinical symptoms such as fever and myalgia. Coinfection may be easily missed and may lead to more severe associated morbidity. This study, therefore, investigated the prevalence of coinfection of influenza A, malaria, and typhoid fever in children in four locations in Lagos and determined their age, gender, and location-related prevalence. Materials and Methods: A cross-sectional hospital-based study was conducted between March and October 2018. Children
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Umma, IdrisA, WammandaD Robinson, FarukA Jamilu, and GarbaD Gwarzo. "Prevalence of malaria parasitaemia among febrile Nigerian children with severe malnutrition in Northwestern Nigeria." Nigerian Journal of Basic and Clinical Sciences 14, no. 2 (2017): 113. http://dx.doi.org/10.4103/njbcs.njbcs_29_16.

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IMORU, Momodu, Umar A. SHEHU, Uchechukwu Gabriel IHESIULOR, and Aminu Haruna KWARU. "Haematological changes in malaria-infected children in North-West Nigeria." TURKISH JOURNAL OF MEDICAL SCIENCES 43 (2013): 838–42. http://dx.doi.org/10.3906/sag-1205-135.

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Abdulkadir, Isa, HafsahAhmad Rufai, SundayOnazi Ochapa, et al. "Malaria rapid diagnostic test in children: The Zamfara, Nigeria experience." Nigerian Medical Journal 56, no. 4 (2015): 278. http://dx.doi.org/10.4103/0300-1652.169744.

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Afolayan, Folake M., Olanrewaju T. Adedoyin, Mohammed B. Abdulkadir, et al. "Acute Kidney Injuries in Children with Severe Malaria." Sultan Qaboos University Medical Journal [SQUMJ] 20, no. 4 (2020): e312-317. http://dx.doi.org/10.18295/squmj.2020.20.04.006.

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Objectives: Serum creatinine levels are often used to diagnose acute kidney injury (AKI), but may not necessarily accurately reflect changes in glomerular filtration rate (GFR). This study aimed to compare the prevalence of AKI in children with severe malaria using diagnostic criteria based on creatinine values in contrast to cystatin C. Methods: This prospective cross-sectional study was performed between June 2016 and May 2017 at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. A total of 170 children aged 0.5–14 years old with severe malaria were included. Serum cystatin C level
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Morenikeji, Olanrewaju B., Jessica L. Metelski, Megan E. Hawkes, et al. "CD209 and Not CD28 or STAT6 Polymorphism Mediates Clinical Malaria and Parasitemia among Children from Nigeria." Microorganisms 8, no. 2 (2020): 158. http://dx.doi.org/10.3390/microorganisms8020158.

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Malaria remains a significant disease, causing epic health problems and challenges all over the world, especially in sub-Saharan Africa. CD209 and CD28 genes act as co-stimulators and regulators of the immune system, while the STAT6 gene has been reported to mediate cytokine-induced responses. Single nucleotide polymorphisms of these genes might lead to differential disease susceptibility among populations at risk for malaria, due to alterations in the immune response. We aim to identify key drivers of the immune response to malaria infection among the three SNPs: CD209 (rs4804803), CD28 (rs35
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Joseph Omang, Antor O Ndep, Dominic Offiong, Fidelis Otu, and Kenneth Onyejose. "Malaria in Pregnancy in Nigeria: A Literature Review." International Healthcare Research Journal 3, no. 11 (2020): 346–48. http://dx.doi.org/10.26440/ihrj/0311.02315.

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Malaria is caused by the parasite plasmodium which can be spread to humans through the bite of an infected mosquito. Of the five types of plasmodium (P. Falciparium, P.Ovale, P. Malaria, P. Vivax and P. Knowlesi), the plasmodium falciparium is the deadliest and affects the lives of almost 40 per cent of the world’s population with pregnant women and children under-five years of age being the most affected. This mini-review involved the collation of findings from recent studies in regards to the prevalence of malaria infection among pregnant women and infants. A systematic analysis of recent li
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Ambe, J. P., S. T. Balogun, M. B. Waziri, I. N. Nglass, and A. Saddiq. "Impacts of Seasonal Malaria Chemoprevention on Malaria Burden among under Five-Year-Old Children in Borno State, Nigeria." Journal of Tropical Medicine 2020 (July 1, 2020): 1–9. http://dx.doi.org/10.1155/2020/9372457.

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Malaria disproportionately affects all ages with a high burden among children below five years. Thus, control measures are deployed including Seasonal Malaria Chemoprevention (SMC). The present study assessed the impacts of SMC on malaria burden among subjects aged 3–59 months in Borno State, Nigeria. Twenty (20) clusters were randomly selected from accessible 16 Local Government Areas (LGAs) of Borno State, Nigeria, and SMC was deployed in 10 of the clusters by administering a full dose of amodiaquine plus sulfadoxine-pyrimethamine at monthly intervals for 4 months consecutively. Three hundre
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Achukwu, N. O., I. B. Enweani, C. C. Aniobi, P. O. Isiofia, and U. S. A. Ogbonna. "Prevalence of Concomitant Infection of Intestinal Helminthiasis with Malaria Parasitaemia in a typical Nigeria Suburban Areas." Nigerian Journal of Parasitology 42, no. 1 (2021): 158–66. http://dx.doi.org/10.4314/njpar.v42i1.21.

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Helminthic infestation and malaria parasitaemia, separately or co- joined, can be present, in a host and still be asymptomatic. It is, therefore, crucial to assess the extent of co-infestation among individuals, particularly children who are most prone to parasitic infestations. Blood and Stool samples were collected from 557 pupils who were examined for intestinal helminths, malaria parasitaemia and anaemia. Formal acetate concentration method was used to analyse the stool specimens after which positive ones were further processed using Stolls method of counting helminths egg to determine the
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Mockenhaupt, Frank P., Jürgen May, Yngve Bergqvist, et al. "Concentrations of Chloroquine and Malaria Parasites in Blood in Nigerian Children." Antimicrobial Agents and Chemotherapy 44, no. 4 (2000): 835–39. http://dx.doi.org/10.1128/aac.44.4.835-839.2000.

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ABSTRACT Consumption of chloroquine (CQ) and subtherapeutic drug levels in blood are considered to be widespread in areas where malaria is endemic. A cross-sectional study was performed with 405 Nigerian children to assess factors associated with the presence of CQ in blood and to examine correlations of drug levels with malaria parasite species and densities. Infections with Plasmodium species and parasite densities were determined by microscopy and PCR assays. Whole-blood CQ concentrations were measured by high-performance liquid chromatography. Plasmodium falciparum, P. malariae, and P. ova
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Ezedinachi, E. N. U., Igbo N. Egwu, M. A. Nwangwa, and J. O. Charles. "Perception of Malaria Infection in Two Rural Communities in Nigeria." International Quarterly of Community Health Education 16, no. 3 (1996): 257–70. http://dx.doi.org/10.2190/fepb-ctm1-v87q-xrbk.

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This investigation was concerned with how and when parents and other members of two rural communities (Awi and Ikot Edem Odo) in Cross River State, Nigeria, recognized malaria infection, what they do to prevent the disease, and what triggers their treatment seeking behaviour (cue to action). The psychological and sociocultural contexts of these complex factors were considered. Focus group discussion (FGD) techniques were employed. A total of eight groups selected using theoretical sampling matrix method were categorized. A thirty-three-item FGD battery of guide questions was used. Information
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Adeola B, Animasahun, Adekunle Motunrayo O, Afadapa Maria A, and Salisu Mohammed A. "PRESUMPTIVE DIAGNOSIS OF MALARIA IN FEBRILE CHILDREN; IS IT JUSTIFIED?" International Journal of Research -GRANTHAALAYAH 5, no. 12 (2020): 291–97. http://dx.doi.org/10.29121/granthaalayah.v5.i12.2017.505.

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Background: Malaria is deadly and a major disease burden in Africa especially among the under-5s. Due to the high death rate from malaria in endemic region, World Health Organization previous recommendation was presumptive treatment of malaria.
 Aim: This study aimed to evaluate if presumptive diagnosis of malaria in our region is still justified, and increase the awareness for proper evaluation for other causes of fever in febrile children.
 Methods: Apart of a single blinded prospective interventional study carried out between March and May 2016, at the children outpatient unit of
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Nwaneri, Damian, and Ayebo Sadoh. "Effect of health seeking behaviour of caregivers on severe malaria outcome in under-fives seen in a tertiary health institution in Nigeria." Ghana Medical Journal 54, no. 3 (2020): 156–63. http://dx.doi.org/10.4314/gmj.v54i3.6.

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Background: Recognition of the symptoms and seeking prompt treatment in a health facility is a major means of reducing morbidity and prevention of mortality from severe malaria in under-fives.Objectives: To document the effect of health-seeking behaviour of caregivers and severe malaria outcome in underfives seen in a tertiary health institution in Nigeria.Design: A descriptive cross-sectional study carried out from July 2012 – June 2013. Data were obtained using a researcher-administered questionnaire.Subjects: Caregivers and children (6 – 59 months) who presented with features of severe mala
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Chukwuocha, Uchechukwu M., Greg N. Iwuoha, Chisom M. Ogara, and Ikechukwu N. S. Dozie. "Malaria classroom corner: a school-based intervention to promote basic malaria awareness and common control practices among school-age children." Health Education 120, no. 1 (2020): 107–19. http://dx.doi.org/10.1108/he-11-2019-0050.

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PurposeThis study assessed the effectiveness of malaria classroom corner (MCC), school-based intervention in the promotion of basic malaria awareness and common control practices among children of primary school age.Design/methodology/approachA quasi-experimental design was employed, involving 206 children of primary 5 and 6 classes from two randomly selected public primary schools in Owerri, South Eastern Nigeria. The MCC was designed and set up in the intervention school (with 103 children) while the control school (with 103 children) was offered malaria health talk. Structured pre-tested qu
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Fawole, O. I., M. O. Onadeko, and C. O. Oyejide. "Knowledge of Malaria and Management Practices of Primary Health Care Workers Treating Children with Malaria in Ibadan, Nigeria." International Quarterly of Community Health Education 22, no. 1 (2003): 95–109. http://dx.doi.org/10.2190/m7ll-kut8-e3np-x7u6.

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A survey of the knowledge and management practices of 61 health workers in five primary health care facilities in Ibadan 30 health workers observed as they managed children with fever and the parasite status of 92 children diagnosed to have malaria was conducted. Sixty-seven percent of children had the malaria parasite. Knowledge on some basic concepts was fairly adequate as the majority (75.4%) knew the cause of malaria, and 95.1% correctly recognized its key signs and symptoms. Treatment practices were poor as only 55.7% and 63.9% of health workers, respectively, prescribed chloroquine and p
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Kuraeiad, Saruda, and Manas Kotepui. "Blood Lead Levels and Subsequence Risk of Malaria in the African Population: A Systematic Review and Meta-Analysis." Tropical Medicine and Infectious Disease 6, no. 3 (2021): 149. http://dx.doi.org/10.3390/tropicalmed6030149.

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Previous epidemiological studies showed that blood lead level (BLL) was associated with malaria infection and severity. Therefore, the present study aimed to qualitatively and quantitatively synthesize the evidence on the association between BLL and risk of malaria infection and severity using the systematic review and meta-analysis approach. Potentially relevant studies were identified from three databases using a combination of search terms. The quality of the included studies was assessed using the checklist for the cross-sectional studies developed by the Joanna Briggs Institute. The quali
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Onyearugha, Chukwuemeka Ngozi, Nneka Chioma Okoronkwo, and Prince Ezenwa Onyemachi. "Malaria: Prevalence and related factors in children at Aba, Southeast Nigeria." Eastern Journal of Medical Sciences 5, no. 3 (2020): 53–56. http://dx.doi.org/10.32677/ejms.2020.v05.i03.002.

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Oyibo, Wellington, Godwin Ntadom, Perpetua Uhomoibhi, et al. "Geographical and temporal variation in reduction of malaria infection among children under 5 years of age throughout Nigeria." BMJ Global Health 6, no. 2 (2021): e004250. http://dx.doi.org/10.1136/bmjgh-2020-004250.

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IntroductionGlobal progress in reducing malaria has stalled since 2015. Analysis of the situation is particularly needed in Nigeria, the country with by far the largest share of the burden, where approximately a quarter of all cases in the world are estimated to occur.MethodsWe analysed data from three nationwide surveys (Malaria Indicator Surveys in 2010 and 2015 and a National Demographic and Health Survey in 2018), with malaria parasite prevalence in children under 5 years of age determined by sampling from all 36 states of Nigeria, and blood slide microscopy performed in the same accredite
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Ejima, I. AA, and I. O. Akinsete. "Prevalence of Asymptomatic Malaria in Relation to Haematological Parameters among Children Attending General Hospital, Minna, Nigeria." NIGERIAN ANNALS OF PURE AND APPLIED SCIENCES 1 (March 13, 2019): 18–25. http://dx.doi.org/10.46912/napas.57.

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Asymptomatic Plasmodium falciparum parasitaemia (APFP) has been reported to be highly prevalent in Sub-Saharan Africa, a region heavily burdened by malaria; yet, the impact of APFP on the haematological reference values have not yet been established in Minna. This study was therefore designed to evaluate the prevalence of asymptomatic malaria in relation to haematological parameters among children attending General Hospital, Minna, Nigeria. After informed consent and clinical examination, blood samples were obtained from the participants for malaria diagnosis and a full blood count. The diagno
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Akuse, Rosamund M., Edwin E. Eseigbe, Abubakar Ahmed, and William R. Brieger. "Patent Medicine Sellers: How Can They Help Control Childhood Malaria?" Malaria Research and Treatment 2010 (September 26, 2010): 1–7. http://dx.doi.org/10.4061/2010/470754.

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Roll Back Malaria Initiative encourages participation of private health providers in malaria control because mothers seek care for sick children from them. This study investigated Patent Medicine Sellers (PMS) management of presumptive malaria in children in order to identify how they can assist malaria control. A cross-sectional survey of 491 PMS in Kaduna, Nigeria, was done using interviews and observation of shop activities. Most (80%) customers bought drugs without prescriptions. Only 29.5% were given instructions about doses. Between 40–100% doses of recommended antimalarials were incorre
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Balogun, S. T., F. A. Fehintola, O. A. Adeyanju, and A. A. Adedeji. "Asexual and sexual stages of Plasmodium falciparum in Nigerian pregnant women attending antenatal booking clinic." Obstetric Medicine 3, no. 3 (2010): 106–9. http://dx.doi.org/10.1258/om.2010.090060.

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Susceptibility to infection by Plasmodium falciparum is increased in pregnant women. In sub-Saharan Africa, the consequences of maternal malaria include preterm birth, fetal growth restriction and increased infant mortality. Malaria transmission requires the circulation of viable gametocytes that can be ingested by the female mosquito taking a blood meal. This study was conducted to evaluate the presence of asexual and sexual stages of P. falciparum in pregnant women attending antenatal booking clinics in south-western Nigeria, an area hyper-endemic for malaria. Gametocyte carriage was about 1
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Omonijo, Adejumoke Oluwatosin, Adetunji Omonijo, Hillary Iwegbunem Okoh, and Azeez Oyemomi Ibrahim. "Relationship between the Usage of Long-Lasting Insecticide-Treated Bed Nets (LLITNs) and Malaria Prevalence among School-Age Children in Southwestern Nigeria." Journal of Environmental and Public Health 2021 (March 25, 2021): 1–9. http://dx.doi.org/10.1155/2021/8821397.

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Purpose. The usage of LLITNs in malaria vector control has resulted in the reduction in malaria deaths among higher-risk groups (pregnant women and under-fives). However, there exists asymptomatic infection among older children, thereby making them a reservoir of malaria transmission. This study aimed at assessing the impact of LLITN usage on malaria prevalence among school-age children (SAC) in Ekiti, South Western Nigeria. Methods. Cross-sectional, two-stage cluster sampling technique was used to collect data from SAC during May and June 2017. A total of 1313 (Oye LGA: 657 and Ikole LGA: 656
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Amodu, Olukemi K., Adesola O. Olumide, Obioma C. Uchendu, Folakemi A. Amodu, and Olayemi O. Omotade. "Differences in the Malariometric Indices of Asymptomatic Carriers in Three Communities in Ibadan, Nigeria." Advances in Preventive Medicine 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/509236.

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This study was conducted to determine the malariometric indices of children in three different settings in Ibadan, Nigeria. Children were recruited from an urban slum (Oloomi) and a periurban (Sasa) and a rural community (Igbanda) in Ibadan. Children aged between 2 and 10 years were randomly selected from primary schools in the urban and periurban areas. In the rural community, children were recruited from the centre of the village. A total of 670 (55.0%) out of 1218 children recruited were positive for malaria parasitaemia. The urban population had the highest proportion of children with mala
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Antia-Obong, O. E., A. A. A. Alaribe, M. U. Young, A. Bassy, and B. V. Etim. "Chloroquine-Resistant Plasmodium Falciparum Among Children in Calabar, South Eastern Nigeria." Tropical Doctor 27, no. 3 (1997): 146–49. http://dx.doi.org/10.1177/004947559702700309.

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Sixty-nine children aged between 6 and 60 months with parasitologically proven Plasmodium falciparum malaria were treated with chloroquine (2.5 mg/kg) in the Children's Emergency Room of the University of Calabar Teaching Hospital (UCTH) in 1993. Thirty subjects (mean age 27.8 months) and 39 (mean age 29.5 months) received chloroquine phosphate suppository (Pharma Deko) and chloroquine sulphate syrup (May & Baker), respectively. The World Health Organization (WHO) 14-day in vivo field test was used in evaluating the response to treatment. In both treatment groups the responses were similar
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Oluyemi, Omoya F., and Ajayi K. Oluyemi. "The Study on the Awareness, Knowledge and Perception of Malaria among Selected Secondary School Students in Akure Metropolis, Nigeria." Open Public Health Journal 10, no. 1 (2017): 1–6. http://dx.doi.org/10.2174/1874944501710010001.

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Background: The negligence of health education and promotion has contributed to increase in morbidity and mortality of malaria among children. Method: This study was carried out in selected secondary schools in Akure, South-western Nigeria to assess the level of awareness, knowledge and perceptive of the use of treated mosquito nets among children of age group 9 and 17 years. 200 pieces of questionnaires were distributed randomly to the respondents. Results and Discussion: Demographic information of respondents, awareness, knowledge and perception on malaria was obtained. 96% of the respondent
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Ramakrishna, Jayashree, William R. Brieger, and Joshua D. Adeimiyi. "Treatment of Malaria and Febrile Convulsions: An Educational Diagnosis of Yoruba Beliefs." International Quarterly of Community Health Education 9, no. 4 (1989): 305–19. http://dx.doi.org/10.2190/yu03-nekj-ttt3-rx0p.

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An understanding of community perceptions of illness, especially disease definitions that are unique to a particular culture, is essential for developing culturally appropriate primary health care programs. Malaria is endemic in the Ibarapa District of Oyo State, Nigeria, and one of its major complications, febrile convulsions, affects nearly one-third of preschool children at least once in their lifetime. Perceptions among the local Yoruba people categorize malaria and convulsions as part of two different disease processes. Ideas of causation, severity, seasonality, and treatment are in many
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Oluwayemi, Oludare Isaac, Biobele Jotham Brown, Olusola Adetunji Oyedeji, Samuel Ademola Adegoke, Olusegun Joseph Adebami, and Gabriel Adebami Oyedeji. "Clinical and laboratory predictors of outcome in cerebral malaria in suburban Nigeria." Journal of Infection in Developing Countries 7, no. 08 (2013): 600–607. http://dx.doi.org/10.3855/jidc.2769.

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Introduction: Cerebral malaria (CM) is an important cause of morbidity and mortality among children living in the tropics. The present study was conducted to update the knowledge on cerebral malaria in children. Methodology: This was a prospective study conducted between June 2009 and February 2010. Consecutive children who met the clinical and parasitological diagnostic criteria for CM were admitted and studied. Demographic, essential history, clinical examination findings and laboratory results were recorded and analyzed. Outcome in survivors (presence or absence of neurological deficits) we
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