Academic literature on the topic 'Malaria parasitemia'

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Journal articles on the topic "Malaria parasitemia"

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Prata, Aluizio, Margarita Urdaneta, Patrick B. McGreevy, and Mauro Shugiro Tada. "Infrequency of asymptomatic malaria in an endemic area in Amazonas, Brazil." Revista da Sociedade Brasileira de Medicina Tropical 21, no. 2 (1988): 51–54. http://dx.doi.org/10.1590/s0037-86821988000200003.

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A malaria survey was conducted in an area of high transmission (Costa Marques, Rondonia, Brazil) to determine the prevalence of asymptomatic parasitemia and its clinical significance. Most of the people surveyed were immigrants who had lived in the endemic area < 5 years. The people had easy access to free diagnostic and treatment services at the Malaria Clinic in the town of Costa Marques. The prevalence of plasmodial parasitemia in 344 people was 22%. There were 36 individuals with asymptomatic infections among the 77 parasitemic patients. During the two days following the initial examina
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Kifude, Carolyne, Deborah Stiffler, David Rockabrand, et al. "Asymptomatic falciparum and Non-falciparum Malarial Parasitemia in Adult Volunteers with and without HIV-1 Coinfection in a Cohort Study in Western Kenya." American Journal of Tropical Medicine and Hygiene 105, no. 1 (2021): 159–66. http://dx.doi.org/10.4269/ajtmh.21-0012.

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Abstract.Asymptomatic malarial parasitemia represents the largest reservoir of infection and transmission, and the impact of coinfection with HIV-1 on this reservoir remains incompletely described. Accordingly, we sought to determine the prevalence of asymptomatic malarial parasitemia in Kombewa, Western Kenya, a region that is endemic for both malaria and HIV-1. A total of 1,762 dried blood spots were collected from asymptomatic adults in a cross-sectional study. The presence of parasitemia was first determined by a sensitive Plasmodium genus–specific 18S assay, followed by less sensitive spe
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Cheruiyot, Agnes C., Jennifer M. Auschwitz, Patricia J. Lee, et al. "Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure forIn VitroMalaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels." Antimicrobial Agents and Chemotherapy 60, no. 4 (2016): 2417–24. http://dx.doi.org/10.1128/aac.00527-15.

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ABSTRACTThe malaria SYBR green assay, which is used to profilein vitrodrug susceptibility ofPlasmodium falciparum, is a reliable drug screening and surveillance tool. Malaria field surveillance efforts provide isolates with various low levels of parasitemia. To be advantageous, malaria drug sensitivity assays should perform reproducibly among various starting parasitemia levels rather than at one fixed initial value. We examined the SYBR green assay standardized procedure developed by the Worldwide Antimalarial Resistance Network (WWARN) for its sensitivity and ability to accurately determine
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Fogang, Balotin, Marie Florence Biabi, Rosette Megnekou, et al. "High Prevalence of Asymptomatic Malarial Anemia and Association with Early Conversion from Asymptomatic to Symptomatic Infection in a Plasmodium falciparum Hyperendemic Setting in Cameroon." American Journal of Tropical Medicine and Hygiene 106, no. 1 (2022): 293–302. http://dx.doi.org/10.4269/ajtmh.21-0316.

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ABSTRACT. Asymptomatic malarial parasitemia is highly prevalent in Plasmodium falciparum endemic areas and often associated with increased prevalence of mild to moderate anemia. The aim of this study was to assess the prevalence of anemia during asymptomatic malaria parasitemia and its interplay with persistent infection in highly exposed individuals. A household-based longitudinal survey was undertaken in a malaria hyperendemic area in Cameroon using multiplex nested polymerase chain reaction to detect plasmodial infections. Residents with P. falciparum asymptomatic parasitemia were monitored
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Ashraf, Shoaib, Areeba Khalid, Arend L. de Vos, Yanfang Feng, Petra Rohrbach, and Tayyaba Hasan. "Malaria Detection Accelerated: Combing a High-Throughput NanoZoomer Platform with a ParasiteMacro Algorithm." Pathogens 11, no. 10 (2022): 1182. http://dx.doi.org/10.3390/pathogens11101182.

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Eradication of malaria, a mosquito-borne parasitic disease that hijacks human red blood cells, is a global priority. Microscopy remains the gold standard hallmark for diagnosis and estimation of parasitemia for malaria, to date. However, this approach is time-consuming and requires much expertise especially in malaria-endemic countries or in areas with low-density malaria infection. Thus, there is a need for accurate malaria diagnosis/parasitemia estimation with standardized, fast, and more reliable methods. To this end, we performed a proof-of-concept study using the automated imaging (NanoZo
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Yusroh, Yoyoh, Bidasari Lubis, Syahril Pasaribu, Munar Lubis, Tiangsa Sembiring, and Adillida Adillida. "Hemolytic anemia in falciparum and vivax malarial patients based on serum bilirubin examination." Paediatrica Indonesiana 44, no. 3 (2016): 95. http://dx.doi.org/10.14238/pi44.3.2004.95-100.

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Objective To examine hemolysis in falciparum and vivax malarialpatients based on serum bilirubin examination.Methods A cross sectional study was conducted on childrenyounger than 15 years of age who visited public health center inthe district of Mandailing Natal with complaints of fever, shivering,pale, jaundice, diarrhea, or headache between April 9 th and April19 th 2001. Variables recorded were age, gender, body weight, bodyheight, symptoms and signs, anti malarial drugs, and laboratorytest results. Thin and thick blood smears were done as diagnostictools of malaria. Thin blood smear was al
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Ouédraogo, Alphonse, Alfred B. Tiono, Amidou Diarra, et al. "Transplacental Transmission ofPlasmodium falciparumin a Highly Malaria Endemic Area of Burkina Faso." Journal of Tropical Medicine 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/109705.

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Malaria congenital infection constitutes a major risk in malaria endemic areas. In this study, we report the prevalence of transplacental malaria in Burkina Faso. In labour and delivery units, thick and thin blood films were made from maternal, placental, and umbilical cord blood to determine malaria infection. A total of 1,309 mother/baby pairs were recruited. Eighteen cord blood samples (1.4%) contained malaria parasites(Plasmodium falciparum). Out of the 369 (28.2%) women with peripheral positive parasitemia, 211 (57.2%) had placental malaria and 14 (3.8%) had malaria parasites in their umb
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Makani, Julie, Albert N. Komba, Sharon E. Cox, et al. "Malaria in patients with sickle cell anemia: burden, risk factors, and outcome at the outpatient clinic and during hospitalization." Blood 115, no. 2 (2010): 215–20. http://dx.doi.org/10.1182/blood-2009-07-233528.

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Abstract Approximately 280 000 children are born with sickle cell anemia (SCA) in Africa annually, yet few survive beyond childhood. Falciparum malaria is considered a significant cause of this mortality. We conducted a 5-year prospective surveillance study for malaria parasitemia, clinical malaria, and severe malarial anemia (SMA) in Dar-es-Salaam, Tanzania, between 2004 and 2009. We recorded 10 491 visits to the outpatient clinic among 1808 patients with SCA and 773 visits among 679 patients without SCA. Similarly, we recorded 691 hospital admissions among 497 patients with SCA and 2017 in p
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Iram, Shagufta, Muhammad Saeed, Shahida Hussain, Ayesha Mobeen, Rabia Jabbar, and Maleeha Aslam. "BURDEN OF MALARIAL PARASITEMIA." Professional Medical Journal 23, no. 04 (2016): 428–33. http://dx.doi.org/10.29309/tpmj/2016.23.04.1501.

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Background : Hematology: 21st century is evolutionary in the arena of medicallaboratory sciences but immunological adverse reactions of blood transfusion and possibletransmission of transfusion transmissible infections are still in their peak. Transmission ofplasmodium via blood is significantly important because only a small fraction of infected redcells of donor blood can lead to cause malarial parasitemia in the recipient. Present studywas planned to determine the frequency of Transfusion based transmissible malaria amongapparently healthy blood donors. Method: This study was conducted in t
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Stevenson, Mary M., Zhong Su, and Mariela Segura. "Regulatory T cells (Tregs) contribute to suppression of anti-malarial immunity by concurrent nematode infection (51.1)." Journal of Immunology 178, no. 1_Supplement (2007): S96. http://dx.doi.org/10.4049/jimmunol.178.supp.51.1.

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Abstract Here, we investigated the mechanisms involved in modulation of anti-malarial immunity by concurrent nematode infection. Both WT C57BL/6 (B6) and STAT-6 deficient (KO) mice co-infected with the gastrointestinal nematode Heligmosomoides polygyrus (Hp) 2 wk prior to blood-stage Plasmodium chabaudi AS (Pc) infection had significantly higher parasitemias and significantly lower serum IFN-γ levels compared to their respective controls infected with Pc alone. Hp-infected STAT-6 KO compared to WT mice produced significantly lower levels of Th2 cytokines (IL-4, IL-13) but Tregs (CD4+CD25+Foxp3
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Dissertations / Theses on the topic "Malaria parasitemia"

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Slabbert, Chrizaan. "Evaluation and validation of methods to determine parasitemia in malaria cell cultures / Chrizaan Slabbert." Thesis, North-West University, 2008. http://hdl.handle.net/10394/2332.

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Domingues, Wilson. "Polimorfismos genéticos de citocinas em indivíduos de área endêmica da Amazônia Legal brasileira com as formas sintomática e assintomática de malária." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/99/99131/tde-21022014-105246/.

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Dentre todas as doenças infecciosas, a malária é a que exerce maior impacto sobre a mortalidade, sobretudo a infantil, em áreas endêmicas. O fato de apenas uma pequena porcentagem de indivíduos que vivem em áreas endêmicas desenvolverem complicações sugere que fatores genéticos do hospedeiro possam exercer papel fundamental. A identificação de polimorfismos genéticos de nucleotídeo único (SNP), associados à suscetibilidade ou proteção contra as formas sintomáticas de malária poderia auxiliar na elaboração de estratégias vacinais. O presente estudo teve como objetivo determinar a frequência de
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Book chapters on the topic "Malaria parasitemia"

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Usluca, Selma. "Malaria and Molecular Diagnosis." In Molecular Approaches in Medicine. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359524.2.

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It is an endemic vector-borne parasitic disease caused by protozoan parasites of the genus Plasmodium in tropical and subtropical regions worldwide. In each endemic area, malaria is transmitted by a specific set of Anopheles species. Plasmodium consists of over 200 species, infecting mammals, birds, and reptiles, and malaria parasites generally tend to be host-specific. Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium knowlesi are the five known species of the genus Plasmodium that causes malaria in humans. Of the five Plasmodium species that cause
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Mhlanga, Nikiwe, and Hendriëtte Van der Walt. "Malaria Diagnostics." In Malaria - Recent Advances, and New Perspectives [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106631.

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The imminent scenario of malaria burden on endemic regions burdens healthcare and is a threat to non-endemic regions. Microscopy and rapid diagnostic tests (RDTs) remain the gold standard for malaria detection in resource-constrained regions. They still present low sensitivity at low parasite density, however, with microscopy also requiring trained personnel, expensive and time consuming. Affordable, rapid, specific, sensitive and simple malaria diagnostics remain elusive. Molecular-based diagnostics, polymerase chain reaction and loop-mediated isothermal amplification, although highly sensiti
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Alemayehu, Aklilu. "Biology and Epidemiology of Malaria Recurrence: Implication for Control and Elimination." In Infectious Diseases Annual Volume 2022 [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108888.

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Malaria recurrence not only increases its clinical episodes, but also sustains transmission. It significantly contributes to a high burden of malaria and impedes elimination. Malaria recurrence can be due to reinfection, relapse, or recrudescence. Based on the type of recurrence, parasites exhibit similar or dissimilar genotypes compared to the genotype involved in initial infection. This review aimed at showing a comprehensive overview of malaria recurrence. Molecular techniques, such as real-time polymerase chain reaction (PCR), nested PCR, multiplex PCR, and sequencing, help to characterize
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Dias Tavares Costa, Alexandre, Anna Caroline Campos Aguiar, Angelina Moraes Silva, and Dhelio Batista Pereira. "Point-of-Care Strategies Applied to Malaria Diagnosis." In Current Topics and Emerging Issues in Malaria Elimination. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96721.

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Rapid and specific diagnosis of malaria remains one of the main strategies to fight the disease. The diagnosis is made primarily by the simple and low-cost thick drop technique, considered the gold standard test. However, the requirement for good quality microscopes and well-trained personnel often lead to inaccurate diagnosis, especially in cases of mixed infections or low parasitemia. Although PCR-based tests can help in these situations, this technique requires large and sensitive equipments, being unsuitable for point of care (POC) settings. A myriad of POC diagnostic tests have being deve
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Mukherjee, Saikat, Soubhik Ghosh, and Arindam Bhattacharyya. "Regulation of T-reg/Th-17 Balance: One Step Closer Towards Immunotherapy Against Malaria Infection." In Plasmodium Species and Drug Resistance [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97045.

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According to World Malaria Report 2020, the rate of decline in malaria case incidence and deaths caused by malaria has ceased in latter half of the past decade. Though Artemisinin Combination Therapy (ACT) is still the major therapeutic approach globally to treat malaria patients, increased resistance of Plasmodium sp. to artemisinin can be looked upon as a major factor responsible for the rate of decline. In the present world, immunotherapeutic approaches are in the limelight to treat several infections, autoimmune disorders, cancers but application of such therapeutic measures in case of mal
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Saini, Sheetal, Rajinder Kumar, and Rajeev K. Tyagi. "Stable Artesunate Resistance in A Humanized Mouse Model of Plasmodium falciparum." In Plasmodium Species and Drug Resistance. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.100381.

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Plasmodium falciparum, the most devastating human malaria parasite, confers higher morbidity and mortality. Although efforts have been made to develop an effective malaria vaccine, stage- and species-specific short-lived immunity crippled these efforts. Hence, antimalarial drug treatment becomes a mainstay for the treatment of malaria infection in the wake of the unavailability of an effective vaccine. Further, there has been a wide array of antimalarial drugs effective against various developmental stages of P. falciparum due to their different structures, modes of action, and pharmacodynamic
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Conference papers on the topic "Malaria parasitemia"

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Kyeremah, Charlotte, Aditya Paul, Daniel Haehn, Manoj T. Duraisingh, and Chandra S. Yelleswarapu. "Phase-support Constraint for Twin-Image Suppression and Phase-Based Classification of Malaria-Infected Red Blood Cells." In Novel Techniques in Microscopy. Optica Publishing Group, 2025. https://doi.org/10.1364/ntm.2025.nth2c.1.

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We developed a phase-support constraint algorithm to suppress twin-image artifacts. We achieved higher parasitemia detection using the optical phase as a classifier compared to features like surface area, which offers reliable holographic microscopy solutions for diagnostics and biomedical imaging.
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Adrial, Adrial, Ellyza Nasrul, and Rosfita Rasyid. "Parasitemia Density Of White Mice Vaccinated of Anopheles Sundaicus Salivary Gland Extract And Plasmodium Berghei Infected As A Model In Fighting Malaria." In Proceedings of the 1st EAI International Conference on Medical And Health Research, ICoMHER November 13-14th 2018, Padang, West Sumatera, Indonesia. EAI, 2019. http://dx.doi.org/10.4108/eai.13-11-2018.2283525.

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Gordon, Paul, Kokou S. Dogbevi, Kevin Kiefer, Susanne U. Mertens-Talcott, and Gerard Coté. "Low cost microscope for malarial parasitemia quantification in microfluidically generated blood smears." In Optics and Biophotonics in Low-Resource Settings VI, edited by David Levitz and Aydogan Ozcan. SPIE, 2020. http://dx.doi.org/10.1117/12.2545213.

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