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Journal articles on the topic 'Malaria – Treatment – Mali'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

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1

Haidara, Mahamane, Geneviève Bourdy, Nunziatina De Tommasi, et al. "Medicinal Plants Used in Mali for the Treatment of Malaria and Liver Diseases." Natural Product Communications 11, no. 3 (2016): 1934578X1601100. http://dx.doi.org/10.1177/1934578x1601100309.

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Today, ethno-pharmacology is a very important resource in order to discover new therapies for the current diseases. Moreover, another good justification for the ethno-pharmacological approach is to obtain new, effective, less expensive and simple therapies, limiting at the same time the cost of pharmaceutical research. Two major anti-malarial drugs widely used today, i.e. quinine and artemisinin, came respectively from Peruvian and Chinese ancestral treatments reported in the traditional medicines. In this contest, there is an urgent need for the discovery of new drugs, due to the critical epi

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2

Cairns, Matthew, Serign Jawo Ceesay, Issaka Sagara, et al. "Effectiveness of seasonal malaria chemoprevention (SMC) treatments when SMC is implemented at scale: Case–control studies in 5 countries." PLOS Medicine 18, no. 9 (2021): e1003727. http://dx.doi.org/10.1371/journal.pmed.1003727.

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Background Seasonal malaria chemoprevention (SMC) has shown high protective efficacy against clinical malaria and severe malaria in a series of clinical trials. We evaluated the effectiveness of SMC treatments against clinical malaria when delivered at scale through national malaria control programmes in 2015 and 2016. Methods and findings Case–control studies were carried out in Mali and The Gambia in 2015, and in Burkina Faso, Chad, Mali, Nigeria, and The Gambia in 2016. Children aged 3–59 months presenting at selected health facilities with microscopically confirmed clinical malaria were re

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3

Dembele, Laurent, Yaw Aniweh, Nouhoum Diallo, et al. "Plasmodium malariae and Plasmodium falciparum comparative susceptibility to antimalarial drugs in Mali." Journal of Antimicrobial Chemotherapy 76, no. 8 (2021): 2079–87. http://dx.doi.org/10.1093/jac/dkab133.

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Abstract Objectives To evaluate Plasmodium malariae susceptibility to current and lead candidate antimalarial drugs. Methods We conducted cross-sectional screening and detection of all Plasmodium species malaria cases, which were nested within a longitudinal prospective study, and an ex vivo assessment of efficacy of a panel of antimalarials against P. malariae and Plasmodium falciparum, both PCR-confirmed mono-infections. Reference compounds tested included chloroquine, lumefantrine, artemether and piperaquine, while candidate antimalarials included the imidazolopiperazine GNF179, a close ana

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4

Diallo, Dapa Aly, Aldiouma Guindo, Boubacari Ali Touré, Yaya Sarro, Baba Fané, and Alain Dorie. "Intermittent Use Of Sufadoxine-Pyrimethamine To Prevent Malaria In Patients With SCD In Malaria Endemic Regions: Findings From The Sickle Cell Disease Research and Control Center Of Bamako, Mali." Blood 122, no. 21 (2013): 1006. http://dx.doi.org/10.1182/blood.v122.21.1006.1006.

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Abstract Sickle cell disease (SCD) is a chronic disorder affecting erythrocytes and is especially prevalent throughout Sub-Saharan Africa where malaria is thought to be a significant cause of morbidity and mortality in affected individuals. In the absence of effective malaria vaccine, one of the affordable alternatives to prevent malaria at present is chemoprophylaxis. In order to evaluate the effectiveness of a monthly intermittent prophylaxis treatment (IPT) with sulfadoxine-pyrimethamine (SP) during high malaria transmission season in patients with sickle cell disease, two groups of SCD pat

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5

Ateba, François Freddy, Manuel Febrero-Bande, Issaka Sagara, et al. "Predicting Malaria Transmission Dynamics in Dangassa, Mali: A Novel Approach Using Functional Generalized Additive Models." International Journal of Environmental Research and Public Health 17, no. 17 (2020): 6339. http://dx.doi.org/10.3390/ijerph17176339.

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Mali aims to reach the pre-elimination stage of malaria by the next decade. This study used functional regression models to predict the incidence of malaria as a function of past meteorological patterns to better prevent and to act proactively against impending malaria outbreaks. All data were collected over a five-year period (2012–2017) from 1400 persons who sought treatment at Dangassa’s community health center. Rainfall, temperature, humidity, and wind speed variables were collected. Functional Generalized Spectral Additive Model (FGSAM), Functional Generalized Linear Model (FGLM), and Fun

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Karimov, I. Z., N. G. Los’-Yatsenko, A. S. Midikari, M. V. Gorovenko, and P. S. Arshinov. "Clinical and epidemiological features of imported malaria in the Republic of Crimea for a twenty-year period (1994-2014)." Kazan medical journal 95, no. 6 (2014): 916–20. http://dx.doi.org/10.17816/kmj2004.

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Aim. To identify the main clinical and epidemiological features of imported malaria in the Republic of Crimea for a twenty year period (1994-2014). Methods. Archival case reports, results of thin and thick blood films for malaria, a set of general clinical and biochemical laboratory parameters were assessed. Results. Over the past 20 years, 48 patients (including 47 men) aged 21 to 61 years were treated for imported malaria in the department of infectious diseases of the 7th City Clinical Hospital in Simferopol. 34 patients were diagnosed with Plasmodium falciparum malaria, 7 - with Plasmodium

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7

Plowe, C. V., A. Djimde, O. K. Doumbo, et al. "Chloroquine treatment of uncomplicated Plasmodium falciparum malaria in Mali: parasitologic resistance versus therapeutic efficacy." American Journal of Tropical Medicine and Hygiene 64, no. 5 (2001): 242–46. http://dx.doi.org/10.4269/ajtmh.2001.64.242.

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8

Thera, Mahamadou, Umberto D'alessandro, Adama Ouedraogo, et al. "Child malaria treatment practices among mothers in the district of Yanfolila, Sikasso region, Mali." Tropical Medicine and International Health 5, no. 12 (2000): 876–81. http://dx.doi.org/10.1046/j.1365-3156.2000.00652.x.

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9

Tekete, Mamadou, Juergen Burhenne, Bakary Fofana, et al. "LUMEFANTRINE DISPOSITION AFTER REPETITIVE TREATMENT OF UNCOMPLICATED MALARIA PATIENTS WITH ARTEMETHER-LUMEFANTRINE IN MALI." BMJ Global Health 2, Suppl 2 (2017): A24.2—A24. http://dx.doi.org/10.1136/bmjgh-2016-000260.61.

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10

Diarra, Modibo, Drissa Coulibaly, Amadou Tapily, et al. "Monitoring of the Sensitivity In Vivo of Plasmodium falciparum to Artemether-Lumefantrine in Mali." Tropical Medicine and Infectious Disease 6, no. 1 (2021): 13. http://dx.doi.org/10.3390/tropicalmed6010013.

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In Mali, since 2007, artemether-lumefantrine has been the first choice against uncomplicated malaria. Despite its effectiveness, a rapid selection of markers of resistance to partner drugs has been documented. This work evaluated the treatment according to the World Health Organization’s standard 28-day treatment method. The primary endpoint was the clinical and parasitological response corrected by a polymerase chain reaction. It was more than 99.9 percent, the proportion of patients with anemia significantly decrease compared to baseline (p < 0.001), and no serious events were recorded. P

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11

Maiga, Hamma, Anastasia Grivoyannis, Issaka Sagara, et al. "Selection of pfcrt K76 and pfmdr1 N86 Coding Alleles after Uncomplicated Malaria Treatment by Artemether-Lumefantrine in Mali." International Journal of Molecular Sciences 22, no. 11 (2021): 6057. http://dx.doi.org/10.3390/ijms22116057.

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Background: Artemether-lumefantrine is a highly effective artemisinin-based combination therapy that was adopted in Mali as first-line treatment for uncomplicated Plasmodium falciparum malaria. This study was designed to measure the efficacy of artemether-lumefantrine and to assess the selection of the P. falciparum chloroquine resistance transporter (pfcrt) and P. falciparum multi-drug resistance 1 (pfmdr1) genotypes that have been associated with drug resistance. Methods: A 28-day follow-up efficacy trial of artemether-lumefantrine was conducted in patients aged 6 months and older suffering

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12

Diallo, Drissa, Bertrand Graz, Jacques Falquet, et al. "Malaria treatment in remote areas of Mali: use of modern and traditional medicines, patient outcome." Transactions of the Royal Society of Tropical Medicine and Hygiene 100, no. 6 (2006): 515–20. http://dx.doi.org/10.1016/j.trstmh.2005.08.003.

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13

ELLIS, AMY A., SEYDOU DOUMBIA, SIDY TRAORÉ, SARAH L. DALGLISH, and PETER J. WINCH. "HOUSEHOLD ROLES AND CARE-SEEKING BEHAVIOURS IN RESPONSE TO SEVERE CHILDHOOD ILLNESS IN MALI." Journal of Biosocial Science 45, no. 6 (2013): 743–59. http://dx.doi.org/10.1017/s0021932013000163.

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SummaryMalaria is a major cause of under-five mortality in Mali and many other developing countries. Malaria control programmes rely on households to identify sick children and either care for them in the home or seek treatment at a health facility in the case of severe illness. This study examines the involvement of mothers and other household members in identifying and treating severely ill children through case studies of 25 rural Malian households. A wide range of intra-household responses to severe illness were observed among household members, both exemplifying and contravening stated so

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14

Coulibaly, Drissa, Seydou Coulibaly, Alassane Dicko, et al. "Impact of preseason treatment on incidence of falciparum malaria and parasite density at a site for testing malaria vaccines in Bandiagara, Mali." American Journal of Tropical Medicine and Hygiene 67, no. 6 (2002): 604–10. http://dx.doi.org/10.4269/ajtmh.2002.67.604.

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15

Dicko, Alassane, Amadou Barry, Mohamed Dicko, et al. "Malaria Morbidity in Children in the Year after They Had Received Intermittent Preventive Treatment of Malaria in Mali: A Randomized Control Trial." PLoS ONE 6, no. 8 (2011): e23390. http://dx.doi.org/10.1371/journal.pone.0023390.

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16

Maiga, Amelia W., Kassim Sanogo, Christopher V. Plowe, et al. "No Evidence of Delayed Parasite Clearance after Oral Artesunate Treatment of Uncomplicated Falciparum Malaria in Mali." American Journal of Tropical Medicine and Hygiene 87, no. 1 (2012): 23–28. http://dx.doi.org/10.4269/ajtmh.2012.12-0058.

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17

de Radiguès, Xavier, Kandian I. Diallo, Mouctar Diallo, et al. "Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali." Transactions of the Royal Society of Tropical Medicine and Hygiene 100, no. 11 (2006): 1013–18. http://dx.doi.org/10.1016/j.trstmh.2006.03.004.

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18

Kayentao, Kassoum, Mamoudou Kodio, Robert D. Newman, et al. "Comparison of Intermittent Preventive Treatment with Chemoprophylaxis for the Prevention of Malaria during Pregnancy in Mali." Journal of Infectious Diseases 191, no. 1 (2005): 109–16. http://dx.doi.org/10.1086/426400.

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19

Sissoko, Sekou, Aminatou Kone, Bakary Fofana, et al. "PF3D7_1343700 KELCH PROPELLER (K13-PROPELLER) POLYMORPHISMS AND ARTESUNATE MONOTHERAPY EFFICACY IN UNCOMPLICATED MALARIA TREATMENT IN MALI." BMJ Global Health 2, Suppl 2 (2017): A18.2—A18. http://dx.doi.org/10.1136/bmjgh-2016-000260.45.

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20

Hurley, Emily A., Steven A. Harvey, Namratha Rao, et al. "Underreporting and Missed Opportunities for Uptake of Intermittent Preventative Treatment of Malaria in Pregnancy (IPTp) in Mali." PLOS ONE 11, no. 8 (2016): e0160008. http://dx.doi.org/10.1371/journal.pone.0160008.

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21

Barger, Breanna, Hamma Maiga, Oumar Bila Traore, et al. "Intermittent preventive treatment using artemisinin-based combination therapy reduces malaria morbidity among school-aged children in Mali." Tropical Medicine & International Health 14, no. 7 (2009): 784–91. http://dx.doi.org/10.1111/j.1365-3156.2009.02294.x.

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22

Sagara, Issaka, Mamady Kone, Sory Ibrahima Diawara, et al. "A Randomized Trial of Artesunate-Mefloquine versus Artemether-Lumefantrine for Treatment of Uncomplicated Plasmodium falciparum Malaria in Mali." American Journal of Tropical Medicine and Hygiene 79, no. 5 (2008): 655–61. http://dx.doi.org/10.4269/ajtmh.2008.79.655.

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23

Maiga, Hamma, Breanna Barger, Issaka Sagara, et al. "Impact of Three-Year Intermittent Preventive Treatment Using Artemisinin-Based Combination Therapies on Malaria Morbidity in Malian Schoolchildren." Tropical Medicine and Infectious Disease 5, no. 3 (2020): 148. http://dx.doi.org/10.3390/tropicalmed5030148.

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Previous studies have shown that a single season of intermittent preventive treatment in schoolchildren (IPTsc) targeting the transmission season has reduced the rates of clinical malaria, all-cause clinic visits, asymptomatic parasitemia, and anemia. Efficacy over the course of multiple years of IPTsc has been scantly investigated. Methods: An open, randomized-controlled trial among schoolchildren aged 6–13 years was conducted from September 2007 to January 2010 in Kolle, Mali. Students were included in three arms: sulphadoxine-pyrimethamine+artesunate (SP+AS), amodiaquine+artesunate (AQ+AS),

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24

Pitt, Catherine, Halimatou Diawara, Dimlawendé J. Ouédraogo, et al. "Intermittent Preventive Treatment of Malaria in Children: A Qualitative Study of Community Perceptions and Recommendations in Burkina Faso and Mali." PLoS ONE 7, no. 3 (2012): e32900. http://dx.doi.org/10.1371/journal.pone.0032900.

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25

Johnson, Ari, Adeline Goss, Jessica Beckerman, and Arachu Castro. "Hidden costs: The direct and indirect impact of user fees on access to malaria treatment and primary care in Mali." Social Science & Medicine 75, no. 10 (2012): 1786–92. http://dx.doi.org/10.1016/j.socscimed.2012.07.015.

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SAGARA, ISSAKA, OGOBARA K. DOUMBO, MOUSSA FOFANA, et al. "A RANDOMIZED TRIAL OF ARTESUNATE–SULFAMETHOXYPYRAZINE–PYRIMETHAMINE VERSUS ARTEMETHER–LUMEFANTRINE FOR THE TREATMENT OF UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA IN MALI." American Journal of Tropical Medicine and Hygiene 75, no. 4 (2006): 630–36. http://dx.doi.org/10.4269/ajtmh.2006.75.630.

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Dicko, Alassane, Abdoulbaki I. Diallo, Intimbeye Tembine, et al. "Intermittent Preventive Treatment of Malaria Provides Substantial Protection against Malaria in Children Already Protected by an Insecticide-Treated Bednet in Mali: A Randomised, Double-Blind, Placebo-Controlled Trial." PLoS Medicine 8, no. 2 (2011): e1000407. http://dx.doi.org/10.1371/journal.pmed.1000407.

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Webster, Jayne, Kassoum Kayentao, Jane Bruce, et al. "Prevention of Malaria in Pregnancy with Intermittent Preventive Treatment and Insecticide Treated Nets in Mali: A Quantitative Health Systems Effectiveness Analysis." PLoS ONE 8, no. 6 (2013): e67520. http://dx.doi.org/10.1371/journal.pone.0067520.

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29

Patterson, Amy E., Peter J. Winch, Kate E. Gilroy, and Seydou Doumbia. "Local terminology for medicines to treat fever in Bougouni District, Mali: implications for the introduction and evaluation of malaria treatment policies." Tropical Medicine and International Health 11, no. 10 (2006): 1613–24. http://dx.doi.org/10.1111/j.1365-3156.2006.01713.x.

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Webster, Jayne, Kassoum Kayentao, Samba Diarra, et al. "A Qualitative Health Systems Effectiveness Analysis of the Prevention of Malaria in Pregnancy with Intermittent Preventive Treatment and Insecticide Treated Nets in Mali." PLoS ONE 8, no. 7 (2013): e65437. http://dx.doi.org/10.1371/journal.pone.0065437.

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Hill, Jenny, Kassoum Kayentao, Mahamoudou Touré, et al. "Effectiveness of Antenatal Clinics to Deliver Intermittent Preventive Treatment and Insecticide Treated Nets for the Control of Malaria in Pregnancy in Mali: A Household Survey." PLoS ONE 9, no. 3 (2014): e92102. http://dx.doi.org/10.1371/journal.pone.0092102.

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32

Maiga, O. M., K. Kayentao, B. T. Traore, et al. "Superiority of 3 Over 2 Doses of Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine for the Prevention of Malaria During Pregnancy in Mali: A Randomized Controlled Trial." Clinical Infectious Diseases 53, no. 3 (2011): 215–23. http://dx.doi.org/10.1093/cid/cir374.

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33

Tekete, Mamadou, Abdoulaye A. Djimde, Abdoul H. Beavogui, et al. "Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali." Malaria Journal 8, no. 1 (2009): 34. http://dx.doi.org/10.1186/1475-2875-8-34.

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Amimo, Floriano, Ben Lambert, Anthony Magit, Jahit Sacarlal, Masahiro Hashizume, and Kenji Shibuya. "Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in Africa: a systematic analysis of national trends." BMJ Global Health 5, no. 11 (2020): e003217. http://dx.doi.org/10.1136/bmjgh-2020-003217.

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IntroductionThe rising burden of drug resistance is a major challenge to the global fight against malaria. We estimated national Plasmodium falciparum resistance to sulfadoxine-pyrimethamine (SP) across Africa, from 2000 to 2020.MethodsWe assembled molecular, clinical and endemicity data covering malaria-endemic African countries up to December 2018. Subsequently, we reconstructed georeferenced patient data, using pfdhps540E and pfdhps581G to measure mid-level and high-level SP resistance. Gaussian process regression was applied to model spatiotemporal standardised prevalence.ResultsIn eastern

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Ellis, Jayne, Prosperity C. Eneh, Kenneth Ssebambulidde, et al. "Case Report: Three's a crowd: a case report examining the diagnostic and pharmacokinetic challenges in HIV-tuberculous meningitis-malaria co-infection." Wellcome Open Research 3 (September 6, 2018): 111. http://dx.doi.org/10.12688/wellcomeopenres.14726.1.

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In 2016, 10.4 million cases of tuberculosis (TB) were reported globally. Malaria also continues to be a global public health threat. Due to marked epidemiological overlap in the global burden of TB and malaria, co-infection does occur. An HIV-infected, 32-year-old male presented with a two-week history of headache with fevers to Mulago National Referral Hospital, Uganda. Five months prior, he was diagnosed with pulmonary TB. He endorsed poor adherence to anti-tuberculous medications. Mycobacterium tuberculosis in CSF was confirmed on Xpert MTB/RIF Ultra. On day 2, he was initiated on dexametha

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Ellis, Jayne, Prosperity C. Eneh, Kenneth Ssebambulidde, et al. "Case Report: Three's a crowd: a case report examining the diagnostic and pharmacokinetic challenges in HIV-tuberculous meningitis-malaria co-infection." Wellcome Open Research 3 (January 15, 2019): 111. http://dx.doi.org/10.12688/wellcomeopenres.14726.2.

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In 2016, 10.4 million cases of tuberculosis (TB) were reported globally. Malaria also continues to be a global public health threat. Due to marked epidemiological overlap in the global burden of TB and malaria, co-infection does occur. An HIV-infected, 32-year-old male presented with a two-week history of headache with fevers to Mulago National Referral Hospital, Uganda. Five months prior, he was diagnosed with pulmonary TB. He endorsed poor adherence to anti-tuberculous medications. Mycobacterium tuberculosis in CSF was confirmed on Xpert MTB/RIF Ultra. On day 2, he was initiated on dexametha

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Naserrudin, Nurul Athirah, Emira Izzati Abdul Aziz, Erdie Aljet, et al. "High incidence of asymptomatic cases during an outbreak of Plasmodium malariae in a remote village of Malaysian Borneo." PLOS Neglected Tropical Diseases 15, no. 6 (2021): e0009450. http://dx.doi.org/10.1371/journal.pntd.0009450.

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An outbreak of Plasmodium malariae occurred in Sonsogon Paliu village in the remote area of Ulu Bengkoka sub-district of Kota Marudu, Northern Sabah, Malaysian Borneo from July through August 2019. This was the first outbreak of malaria in this village since 2014. On 11th July 2019 the Kota Kinabalu Public Health Laboratory notified the Kota Marudu District Health Office of a Polymerase Chain Reaction (PCR) positive case of P. malariae. This index case was a male from Sulawesi, Indonesia working for a logging company operating in Sonsogon Paliu. During the resulting outbreak, a total of 14 sym

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Borkow, Gadi. "Editorial: Fighting Infections in Developing Countries by Cost-Affordable and Sustainable Means." Open Biology Journal 3, no. 1 (2010): 72–73. http://dx.doi.org/10.2174/18741967010030100072.

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In developing areas around the globe it is extremely hard for health related institutions and governments to implement prevention and treatment policies, to improve public health, due to poor economical resources and infrastructures; low awareness; inadequate personnel; high prevalence of parasites and pathogens with extreme infection burdens, as well as sociopolitical factors. Central government programs essential for the improvement of the general public health are limited in developing countries. These include mass vaccination programs, which are cornerstones of primary health-care [1]; pro

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Parise, Éldi Vendrame, Gessi Carvalho de Araújo, José Gerley Diaz Castro, and Fernando Pedroso Berdarrain. "Epidemiological profile of malaria in the state of Tocantins, Brazil, from 2003 to 2008." Revista do Instituto de Medicina Tropical de São Paulo 53, no. 3 (2011): 141–47. http://dx.doi.org/10.1590/s0036-46652011000300005.

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This study describes the epidemiological profile of malaria in the State of Tocantins, in the period 2003-2008, investigates the association between the frequency of malaria and population growth, classifies the cases by 'autochthonous' and 'imported', reports the indices of the disease and analyses the distribution of the cases by Plasmodium species, age and gender. The retrospective study was based on secondary data, stored in SIVEP-malaria and analyzed using the software Epi-Info 3.5.1. and Bioestat 5.0. 19,004 samples were investigated for malaria, 19% of them were positive, 73.32% with Pl

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O'Neill, Therese, and Brian McCaffrey. "Further support from an Irish psychiatric hospital for lack of value of routine serological tests for syphilis." Irish Journal of Psychological Medicine 6, no. 2 (1989): 142–43. http://dx.doi.org/10.1017/s0790966700015494.

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AbstractSince the establishment of St. Brendan's Hospital in 1815 many changes have been seen in the pattern of psychiatric illness but none as dramatic as that of neurosyphilis. When Professor John Dunne first worked there in 1922, 20% of the patients suffered from general paralysis of the insane (G.P.I.) for which there was no cure. Around this time Wagner Von Jauregg – a Viennese physician, observed that patients who had suffered malaria during war did not suffer from G.P.I. He introduced malarial therapy successfully for which he received the Nobel Prize in 1927. Professor Dunne introduced

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Omoirri Moses Aziakpono, Madubogwu Ngozi Ukamaka, Oraekei Daniel Ikechukwu, Ataihire Johnson Uyovwiesevwa, Chukwuemeka Charles Ofili, and Mbata Uchenna Chisom. "Anti-malaria and hypoglycaemic activities of Diosgenin on alloxan-induced, diabetic Wistar rats." GSC Biological and Pharmaceutical Sciences 15, no. 3 (2021): 073–79. http://dx.doi.org/10.30574/gscbps.2021.15.3.0102.

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The rising threat of Plasmodium falciparum resistance to Monotherapies has prompted the world health organization (WHO) 2006 guidelines to recommend the use of different anti-malarias. In this study, the anti-malaria and hypoglycaemic activities of Diosgenin, a potent, yet poorly reported saponin was investigated on P. falciparum inoculated and Alloxan-Induced, Diabetic Wistar Rats. Fort two (42) adult male wistar rats of between 100g and 150g were procured, acclimatized (for two weeks), and grouped into seven of six (6) rats per group. While Group 1 (Normal control) received normal rat chow a

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Baluku, Joseph Baruch, Sylvia Nassozi, Brian Gyagenda, et al. "Prevalence of Malaria and TB Coinfection at a National Tuberculosis Treatment Centre in Uganda." Journal of Tropical Medicine 2019 (July 25, 2019): 1–7. http://dx.doi.org/10.1155/2019/3741294.

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The prevalence of malaria and tuberculosis (TB) coinfection is not well established in countries that are highly burdened for both diseases. Malaria could impair TB containment and increase mortality of TB patients. The objective of this study was to determine the prevalence of malaria/TB coinfection among bacteriologically confirmed adult TB patients at a national TB treatment centre in Uganda. Using a cross-sectional study design we enrolled 363 bacteriologically confirmed adult TB patients, and data on demographics and medical history was collected. Blood samples were tested for malaria blo

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Shah, Punit J., Janice Koshy, Nichelle Everett, and Engie Attia. "Severe Plasmodium falciparum Malaria Treated With Investigational Artesunate in the United States." Journal of Pharmacy Practice 33, no. 1 (2018): 108–12. http://dx.doi.org/10.1177/0897190018782367.

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Purpose: We describe here the case of a 40-year-old Nigerian male with severe Plasmodium falciparum malaria successfully treated with investigational intravenous (IV) artesunate. Summary: A 40-year-old Nigerian male was admitted to the medical intensive care unit for the treatment of severe malaria. The patient presented with the classic malaria paroxysm and altered mental status and was in acute renal failure. A blood parasite, thick and thin smear was performed revealing positive ring forms on smear which are characteristic of Plasmodium falciparum, with an estimated parasitemia of 2%. Per t

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Durrani, Muhammad Rasheed Khan, Tahreem Shafi, Zinnia Ali, and Muhammad Danial Iqbal. "CERBRAL MALARIA." Professional Medical Journal 25, no. 01 (2018): 45–49. http://dx.doi.org/10.29309/tpmj/2018.25.01.536.

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Cerebral malaria is a disease entity which we commonly come across and that itshould be suspected in every patient with impairment of conscious level and high spiking feverespecially with no history of trauma. Early treatment is crucial and can be lifesaving. There aretwo treatment option in which one is conventional Quinine Dihydrochloride and other artmisinininfusion. Objectives: To study the outcomes of Quinine dihydrochloride and artemisininpractice in patients with cerebral malaria in terms of acceptance and response. Study Design:Descriptive cohort study. Place and Duration of Study: Dep

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Maryanto, Yusuf Budi, and Yudied Agung Mirasa. "The Overview of Malaria Cases in Trenggalek District based on The Epidemiological Triangle." Jurnal Berkala Epidemiologi 7, no. 1 (2019): 33. http://dx.doi.org/10.20473/jbe.v7i12019.33-41.

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Background: Indonesia is one of the countries where 35% of the population lives in areas with a high risk of malaria infection. Trenggalek is one of the malaria-endemic regions in East Java. Purpose: This study aimed to identify the malaria cases in Trenggalek based on the epidemic triangle and identify the vulnerability status of Anopheles vagus mosquito against Permethrin 0.75% in Pandean Village, Trenggalek. Methods: This study is a type of descriptive observational study. The data used in this study is secondary data obtained from the The Center of Environmental Health and Disease Control

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Roberson, Megan, and Austin Smith. "Cerebral Malaria in a Patient with Recent Travel to the Congo Presenting with Delirium: A Case Report." Clinical Practice and Cases in Emergency Medicine 4, no. 4 (2020): 533–36. http://dx.doi.org/10.5811/cpcem.2020.8.47995.

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Introduction: Cerebral malaria, a syndrome of altered consciousness, is a rare and severe neurologic complication resulting from Plasmodium falciparum.1 Historically, cerebral malaria has been seen more frequently in children rather than adults. To complicate the diagnosis, cerebral malaria has few specific symptoms and neurologic findings can vary with each case. Case Report: We describe a case of a 61-year-old male who returned from the Democratic Republic of Congo and presented to the emergency department with dehydration, fatigue, and intermittent confusion. He was ultimately diagnosed wit

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Kabongo Kamitalu, Ramsès, and Michel Ntetani Aloni. "High School Students Are a Target Group for Fight against Self-Medication with Antimalarial Drugs: A Pilot Study in University of Kinshasa, Democratic Republic of Congo." Journal of Tropical Medicine 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/6438639.

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Aim. To assess the self-medication against malaria infection in population of Congolese students in Kinshasa, Democratic Republic of Congo (DRC).Methods. A cross-sectional study was carried out in University of Kinshasa, Kinshasa, Democratic Republic of Congo. Medical records of all students with malaria admitted to Centre de Santé Universitaire of University of Kinshasa from January 1, 2008, to April 30, 2008, were reviewed retrospectively.Results. The median age of the patients was 25.4 years (range: from 18 to 36 years). The majority of them were male (67.9%). Artemisinin-based combination

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Adeola B, Animasahun, Adekunle Motunrayo O, Afadapa Maria A, and Salisu Mohammed A. "PRESUMPTIVE DIAGNOSIS OF MALARIA IN FEBRILE CHILDREN; IS IT JUSTIFIED?" International Journal of Research -GRANTHAALAYAH 5, no. 12 (2020): 291–97. http://dx.doi.org/10.29121/granthaalayah.v5.i12.2017.505.

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Background: Malaria is deadly and a major disease burden in Africa especially among the under-5s. Due to the high death rate from malaria in endemic region, World Health Organization previous recommendation was presumptive treatment of malaria. Aim: This study aimed to evaluate if presumptive diagnosis of malaria in our region is still justified, and increase the awareness for proper evaluation for other causes of fever in febrile children. Methods: Apart of a single blinded prospective interventional study carried out between March and May 2016, at the children outpatient unit of

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I., Jalo, Isaac E. Warnow, Aliu R., and Hassan K. Shina. "Burden, clinical manifestation and outcome of severe malaria in children at a tertiary hospital in Northeast, Nigeria." International Journal of Contemporary Pediatrics 7, no. 8 (2020): 1659. http://dx.doi.org/10.18203/2349-3291.ijcp20203158.

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Background: Severe malaria is a life-threatening medical emergency and requires prompt and effective treatment to prevent death. The presentation of severe malaria varies depending on such factors as country, age, immunity, socioeconomic factors, drug resistance and type of intervention measures used. The aim of this study is to document the burden and forms of severe malaria in children in this region. Objective of this study was to determine the prevalence, clinical manifestation and outcome of children with severe malaria in Federal Teaching Hospital, GombeMethods: Case notes of patients ad

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Olapeju, Bolanle, Camille Adams, Gabrielle Hunter, et al. "Malaria prevention and care seeking among gold miners in Guyana." PLOS ONE 15, no. 12 (2020): e0244454. http://dx.doi.org/10.1371/journal.pone.0244454.

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Despite being a priority population in malaria elimination, there is scant literature on malaria-related behavior among gold miners. This study explores the prevalence and factors influencing malaria prevention, care seeking and treatment behaviors in Guyana gold mining camps. A cross sectional survey was conducted among adult gold miners living in mining camps in the hinterland Regions 1 (Barima-Waini), 7 (Cuyuni-Mazaruni), and 8 (Potaro-Siparuni). Multivariable logistic regressions explored factors associated with miners’ self-report of mosquito net use, prompt care-seeking; self-medication;

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