Academic literature on the topic 'Malaria – Zambia'
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Journal articles on the topic "Malaria – Zambia"
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Steury, Elinda Enright. "Malaria Prevention in Zambia." Journal of Transcultural Nursing 24, no. 2 (January 22, 2013): 189–94. http://dx.doi.org/10.1177/1043659612472061.
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Chanda, Emmanuel, Mulakwa Kamuliwo, Richard W. Steketee, Michael B. Macdonald, Olusegun Babaniyi, and Victor M. Mukonka. "An Overview of the Malaria Control Programme in Zambia." ISRN Preventive Medicine 2013 (December 9, 2013): 1–8. http://dx.doi.org/10.5402/2013/495037.
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The Zambian national malaria control programme has made great progress in the fight against Malaria. The country has solid, consistent, and coordinated policies, strategies, and guidelines for malaria control, with government prioritizing malaria in both the National Health Strategic Plan and the National Development Plan. This has translated into high coverage of proven and effective key preventive, curative, and supportive interventions with concomitant marked reduction in both malaria cases and deaths. The achievements attained can be attributed to increased advocacy, communication and behaviour changes, efficient partnership coordination including strong community engagement, increased financial resources, and evidence-based deployment of key technical interventions in accordance with the national malaria control programme policy and strategic direction. The three-ones strategy has been key for increased and successful public-private sector partner coordination, strengthening, and mobilization. However, maintaining the momentum and the gains is critical as the programme strives to achieve universal coverage of evidence-based and proven interventions. The malaria control programme’s focus is to maintain the accomplishments, by mobilizing more resources and partners, increasing the government funding towards malaria control, scaling up and directing interventions based on epidemiological evidence, and strengthen active malaria surveillance and response to reduce transmission and to begin considering elimination.
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Shimaponda-Mataa, Nzooma M., Enala Tembo-Mwase, Michael Gebreslasie, and Samson Mukaratirwa. "Knowledge, attitudes and practices in the control and prevention of malaria in four endemic provinces of Zambia." Southern African Journal of Infectious Diseases 32, no. 1 (March 31, 2017): 29–39. http://dx.doi.org/10.4102/sajid.v32i1.67.
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This study sought to determine malaria knowledge levels, attitudes and practices of the communities in four malaria endemic provinces of Zambia. A cross-sectional survey on knowledge, attitude and practices (KAP) on malaria transmission, prevention and control was conducted among 584 household heads of randomly selected communities in Luapula, Lusaka, north-western and western provinces in Zambia. Data analysis was performed by both descriptive and inferential statistics. Knowledge levels in malaria with regards to the mosquito being the vector and the capacity of malaria to kill were high in all the provinces and did not vary statistically. The two main sources of malaria information by weighted analysis were health facility and community health workers (CHWs). From the regression analysis, pain killer use was associated with high incomes, employment, secondary education, or higher, and the knowledge of fever as a sign for malaria. Additionally, the source of malaria information was related to education levels. There is a need to enhance information through available channels such as health facilities and CHWs and tailor them according to general education levels of a community.
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Phiri, James S. "Malaria Control in Zambia and Southern Africa." Environmental Health Perspectives 103, no. 7/8 (July 1995): 644. http://dx.doi.org/10.2307/3432851.
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Phiri, J. S. "Malaria control in Zambia and southern Africa." Environmental Health Perspectives 103, no. 7-8 (January 1995): 644–45. http://dx.doi.org/10.1289/ehp.95103644b.
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Singer, Emily. "International partnership launches malaria model in Zambia." Nature Medicine 11, no. 7 (July 2005): 695. http://dx.doi.org/10.1038/nm0705-695b.
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Kupferschmidt, K. "Zambia fights to sustain its malaria success." Science 345, no. 6202 (September 11, 2014): 1270–71. http://dx.doi.org/10.1126/science.345.6202.1270.
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Butler, Declan. "Zambia to wage ‘scientific’ war on malaria." Nature 435, no. 7041 (May 2005): 395. http://dx.doi.org/10.1038/435395a.
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McClean, Karen L., and A. Senthilselvan. "Mosquito Bed Nets: Implementation in Rural Villages in Zambia and the Effect on Subclinical Parasitaemia and Haemoglobin." Tropical Doctor 32, no. 3 (July 2002): 139–42. http://dx.doi.org/10.1177/004947550203200306.
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Malaria continues to be an increasing health concern in many endemic areas where it remains a major contributor to childhood morbidity and mortality. Chemoprophylaxis and treatment are increasingly compromised by drug resistance. Vaccination for malaria is not yet available outside clinical trials. In clinical trials bed nets have been shown to be effective in reducing malarial morbidity and mortality. Their efficacy outside of the clinical trial setting has been less well documented. We describe our experience with the introduction of bed nets in a remote rural Zambian village and document the effect on malarial parasitaemia, spleen rates and haemoglobin. Children were evaluated at the end of the rainy seasons in April 1998 and April 1999. Insecticide impregnated nets were made available for purchase to the village in July 1998. Rates of parasitaemia and anaemia were significantly reduced.
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Lubinda, Jailos, Yaxin Bi, Busiku Hamainza, Ubydul Haque, and Adrian J. Moore. "Modelling of malaria risk, rates, and trends: A spatiotemporal approach for identifying and targeting sub-national areas of high and low burden." PLOS Computational Biology 17, no. 3 (March 1, 2021): e1008669. http://dx.doi.org/10.1371/journal.pcbi.1008669.
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While mortality from malaria continues to decline globally, incidence rates in many countries are rising. Within countries, spatial and temporal patterns of malaria vary across communities due to many different physical and social environmental factors. To identify those areas most suitable for malaria elimination or targeted control interventions, we used Bayesian models to estimate the spatiotemporal variation of malaria risk, rates, and trends to determine areas of high or low malaria burden compared to their geographical neighbours. We present a methodology using Bayesian hierarchical models with a Markov Chain Monte Carlo (MCMC) based inference to fit a generalised linear mixed model with a conditional autoregressive structure. We modelled clusters of similar spatiotemporal trends in malaria risk, using trend functions with constrained shapes and visualised high and low burden districts using a multi-criterion index derived by combining spatiotemporal risk, rates and trends of districts in Zambia. Our results indicate that over 3 million people in Zambia live in high-burden districts with either high mortality burden or high incidence burden coupled with an increasing trend over 16 years (2000 to 2015) for all age, under-five and over-five cohorts. Approximately 1.6 million people live in high-incidence burden areas alone. Using our method, we have developed a platform that can enable malaria programs in countries like Zambia to target those high-burden areas with intensive control measures while at the same time pursue malaria elimination efforts in all other areas. Our method enhances conventional approaches and measures to identify those districts which had higher rates and increasing trends and risk. This study provides a method and a means that can help policy makers evaluate intervention impact over time and adopt appropriate geographically targeted strategies that address the issues of both high-burden areas, through intensive control approaches, and low-burden areas, via specific elimination programs.
Dissertations / Theses on the topic "Malaria – Zambia"
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Mwale, Evans L. "Assessment of the clinical management of children suspected of having malaria in Lusaka District, Zambia." University of the Western Cape, 2016. http://hdl.handle.net/11394/4909.
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Magister Public Health - MPHIn Zambia, there had been a large scaling up of new interventions to control malaria since 2003, which included the distribution of rapid diagnostic tests (RDTs), used to immediately determine if someone with symptoms suggestive of malaria actually has malaria; training of health workers in the use of the RDTs; and the prescription of artemisinin-based combination therapy (ACT) to which the malaria parasite is sensitive, rather than the old treatment regime of chloroquine to which the malaria parasite had become resistant. The use of RDTs to confirm the presence of malaria before treating for it with ACT became known as the „test and treat‟ policy. Previously, since the 1960s, in malaria endemic areas such as Zambia, children presenting with fever (the commonest symptom of malaria) without any obvious other cause for the fever, were assumed to have malaria and were hence treated for it with chloroquine. This was known as "presumptive treatment" of malaria. The combination of "presumptive treatment" and the use of a single medication led to the development of high levels of resistance to chloroquine, to the extent that it is now no longer an effective treatment for malaria. Years after the introduction of the "test and treat" policy, it was still unclear to what extent it was being implemented, as there was initial reluctance by health workers to test all children presenting with fever for malaria and if they did test they may not have followed the management guidelines of treating those who test positive with ACT and further investigating those who test negative for the cause of the fever. It seemed that staff had gotten used to the "presumptive treatment" approach to malaria over almost 4 decades and hence were quite reluctant to abandon it. The conflicting guidelines for malaria treatment in children between IMCI and "test and treat‟ has promoted a paradox between presumptive treatment for malaria and "test and treat" approach as IMCI teaches health workers to treat febrile children presumptively for malaria whereas the "test and treat" approach requires them to first make a definitive diagnosis before treating. Hence although the "test and treat" approach was instituted to overcome the problems with presumptive treatment approach it now had to contend with the competing and contradictory influence of the IMCI approach. This study therefore aimed to assess what proportion of children aged five years and younger who presented with fever were managed via the "test and treat" guidelines and which factors were associated with this, in Lusaka District, Zambia. Methodology: A cross sectional analytical study design was used based on a review of medical records. A sample size of 800 medical records of children presenting with fever was selected from 10 out of the 23 health care facilities in Lusaka, using a multistage stratified random sampling technique. Four hundred records were sampled from 2008 records (five years after commencement of the "test and treat" policy) and 400 from 2011 records (eight years after commencement of the "test and treat" policy). Trained data collectors used a data extraction tool to transcribe demographic and clinical data from the medical records in a standardized manner. Data Analysis: Univariate descriptive statistics analysis was performed using measures of central tendency and measures of dispersion to analyze numerical (continuous) variables such as age, weight and body temperature; and using frequencies for categorical variables such as gender, area of residence, RDTs/microscopy malaria tests conducted, received ACT if RDT positive, presence of an ACT treatment chart on the health centre wall and availability of a weighing scale. To determine the relationship between variables, bivariate analysis via the prevalence ratio was conducted. Results: Just over half (55%) of all children with fever were tested for malaria in 2008 and this gratifyingly increased to (73%) in 2011. Overall, the proportion of children correctly and appropriately treated with ACT, which means that those who tested positive for malaria were given ACT, was 85% in 2008 but regrettably dropped to 72% in 2011. Although "presumptive treatment" decreased from 24% in 2008 to 11% in 2011, the proportion of children with fever not tested for malaria, and although not treated for malaria, but left without a definitive diagnosis of their fever being made, remained high but dropping (22% in 2008 and 16% in 2011). Similarly the proportion of children who tested negative for malaria but then did not undergo any further investigation also unfortunately remained very high and rising (57% in 2008 and 89% in 2011). A combination of the above poor clinical management practises resulted in only 38% of children with fever in 2008 and unfortunately dropping to only 33% in 2011 being correctly managed (tested for malaria via RDT or microscopy and treated with ACT if positive, while further investigated for the cause of fever if negative). On preparedness of the health facility to implement the "test and treat" policy, it was noted that only 4 out of 10 health facilities were at least minimally prepared to do so, but paradoxically on bivariate analysis those minimally prepared were less likely (PR 0.62; 95% CI 0.41-0.94) to correctly manage the patients in 2011 than those who were unprepared. A similar paradox occurred for those correctly treated with ACT after testing positive, with facilities which were minimally prepared being less likely to do so (PR 0.28; 95% CI 0.14-0.58) in 2011 than those facilities which were unprepared to implement the "test and treat" policy. However these associations were inconsistent over time, as the associations were not present in 2008. Similarly all other factors such as staff category (doctor, nurse, clinical officer) and type of presenting symptoms besides fever (anorexia, lethargy, pallor) assessed, were not consistently associated with testing for malaria in both 2008 and 2011. The same applied for the other two main outcome variables of 'treated with ACT after test positive for malaria' and 'correctly managed child with fever', in that there were no factors that showed a consistent association with them in both 2008 and 2011. Conclusion: Testing of children with fever for malaria is at a low level but rose between 2008 and 2011. Paradoxically the proportion of those diagnosed with malaria who were correctly treated with ACT dropped between 2008 and 2011, as did the proportion of children with fever who were correctly managed. No factors assessed in this study were found to be consistently associated in both 2008 and 2011 with either testing for malaria, or treating confirmed malaria cases with ACT, or managing patients with fever correctly. Recommendations: In order for health workers to correctly implement the "test and treat" policy, which involves a series of complex steps, they ought to be formally trained to do so, mentored and constructively supervised. Additionally health facilities should be adequately equipped to enable health workers to fully implement the policy. Further studies to assess factors associated with the correct management of malaria via the "test and treat" policy are warranted.
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Steury, Elinda. "Mobile Phone Short Message Service (SMS) to Improve Malaria Pharmacoadherence in Zambia." Doctoral diss., University of Central Florida, 2014. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/6362.
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Malaria significantly contributes to morbidity and mortality rates in Zambia. The currently accepted malaria treatment is artemisinin-based combination therapy (ACT); it is more than 97% effective when the regimen is strictly adhered to. However, the mean ACT adherence rate in sub-Saharan Africa is only approximately 38-48%. Poor pharmacoadherence remains a significant barrier to malaria control and elimination.
The purpose of this study was to determine if adherence rates to a six-dose ACT antimalarial treatment differ between patients in Zambia who received short message service (SMS) reminders and those who did not.
An experimental, randomized, controlled trial was conducted to collect data from a sample of 96 adult patients with malaria who presented to Fisenge Clinic in the Copperbelt Province of Zambia. Participants were randomly assigned to a control or intervention group. The intervention group received SMS messages to remind them to take their medication according to the regimen. An electronic pillbox was used to measure pharmacoadherence for both groups, and patients were classified as probably adherent or probably non-adherent.
Data were analyzed using Chi-square for association between the SMS intervention and pharmacoadherence, and logistic regression used for predictors of adherence. No significant association was found between SMS reminders and pharmacoadherence among malaria patients being treated with ACT when evaluated with respect to those who received the SMS reminders and those who did not (?2=0.19, df=1, p=0.67). Binary logistic regression indicated that there were no variables associated with adherence (p>0.05).
Findings from this study contribute to the research regarding the use of mobile phones to promote adherence. This is the first study of its kind using SMS directly to the patient for ACT adherence in sub-Saharan Africa known to the author. It is possible that the use of the electronic pillbox and/or the novelty of participating in a research study contributed to higher levels of adherence than previously found in this geographical area. While data suggested that there was no association between SMS and adherence, further research is needed to explore the value of this intervention.Ph.D.
Doctorate
Nursing
Nursing
Nursing
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Badat, Akbar Yusuf. "The Trends and Characteristics of Donor Funding Patterns of National Tuberculosis, Malaria and HIV Programs in Zambia." Thesis, University of the Western Cape, 2008. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_5335_1266199523.
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The study aims to assess the characteristics of donor funding for national tuberculosis, malaria and HIV programmes to Zambia over an 8 year period in order to inform it&rsquo
s more effective and efficient utilization.
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Chanda, Emmanuel. "Optimizing impact assessment of entomological intervention for malaria control in an operational setting in Zambia." Thesis, University of Liverpool, 2011. http://livrepository.liverpool.ac.uk/3413/.
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The study aimed at optimally assessing the impact of indoor residual spraying (IRS) and insecticide treated nets (ITNs) on vector species abundance, their infectivity and resistance status, and Plasmodium falciparum prevalence, malaria deaths and case fatality rates in the human population. Malaria prevalence surveys were conducted and routine surveillance data was retrospectively analyzed. The average P. falciparum prevalence in children between the ages of 1 and 14 years was below 10% across the study period. The intervention effect was more pronounced in IRS areas than in ITNs localities but with an incremental protective effect of their combined use. Age-specific comparison showed better intervention effect on children below 5 years than older children 5 to 14 years old. While the average number of deaths and case fatality rates in children under the age of five plunged precipitately, the reductions were more significant in IRS districts than in ITNs districts. Results indicate the need for supplementing parasite prevalence survey data with routine surveillance data in low transmission intensity areas and demonstrate the significance of evidence-based age-specific deployment of interventions. To monitor vector species abundance and infectivity, mosquitoes were collected daily using exit window traps. The three major vectors; An. gambiae s.s, An. arabiensis and An. funestus s.s, and three potential vectors of malaria, An. nili, An. rivulorum and An. funestus-like species were identified. Overall, the biggest impact of IRS and ITNs was on An. gambiae s.s, and An. funestus abundance. No An. gambiae s.s was collected in IRS localities, thus validating the fact that An. gambiae s.s and An. funestus are characteristically more amenable to control by IRS and ITNs than An. arabiensis. The transmission potential for all malaria vectors, as expressed by the calculated transmission index, was zero as none of the trapped mosquitoes tested positive for P. falciparum sporozoites. The identification of An. nili, An. rivulorum and An. funestus-like necessitate further research to determine their role in malaria transmission in the country. The low numbers of mosquitoes collected also indicate a compromise in the efficiency of exit window traps in low transmission settings, suggesting the need for their replacement with a more robust collection tool like the CDC light trap. While the persistence of An. arabiensis suggests the presence of resistance segregating in this population or, that this outdoor species is not in contact with IRS or ITNs, it could as well imply that it’s the one species perpetuating malaria transmission in these meso-to hypo- endemic areas. To determine the impact of interventions on insecticide resistance status of malaria vectors, susceptibility assays using the WHO standard protocol were conducted in 17 localities. High levels of resistance were detected in both An, gambiae s.l and An, funestus s.l to pyrethroids and DDT but with 100% susceptibility to malathion and bendiocarb. The level of resistance was significantly higher in IRS areas than in ITN areas. These findings indicate that resistance has been selected for following extensive vector control. Resistance to both DDT and deltamethrin in IRS localities and ITN areas with intense cotton growing was detected suggesting selection due to either historical use of DDT, gene flow or cross-resistance. All An. gambiae s.s were molecular s-forms and only the west (leu-phe) kdr was detected. Complete susceptibility to the organophosphates and carbamates provides a possibility to switch to these alternative insecticide classes for IRS. The detected increases in the malaria prevalence in localities with high insecticide resistance levels indicate vector control failure. These findings point to the need for information on underlying biochemical and molecular resistance mechanisms to make possible the design of an effective resistance management strategy, and for the assessment of the impact of resistance on interventions. The results indicate that the impact of malaria control can be optimally assessed by using a combination of epidemiological (routine surveillance and prevalence data) and entomological indicators, in the context of a malaria decision support system, to enhance policy formulation for objective implementation of malaria control interventions and rational use of available resources.
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Chanda, Pascalina. "Cost and cost-effectiveness analysis of the available strategies for diagnosing malaria in outpatient clinics in Zambia." Master's thesis, University of Cape Town, 2006. http://hdl.handle.net/11427/9432.
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Includes bibliographical references (leaves 114-123).Malaria is a major public health problem in Zambia accounting for more than 3 million clinical cases and about 33,000 deaths annually. Artemether-Iumefantrine, (a relatively expensive drug) is being used for first line treatment of uncomplicated malaria. However, diagnostic capacity in Zambia is low, which has both economical, and health implications for the health system. The current alternatives for diagnosis of malaria are clinical, microscopy and rapid diagnostic tests (RDTs). This study consists of an economic evaluation of the alternative malaria diagnosis methods in outpatient facilities in Zambia. The study is expected to contribute to effective decision-making in Zambia, especially when considering scaling up malaria diagnosis in health facilities.
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Klačková, Zuzana. "Mikrofinancie ako nástroj rozvojovej pomoci." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-75295.
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In the 20th century, microfinance went through a revolution: the number of microfinance was expanding exponentially all over the world. Microfinances are supposed to be one of the most efficient tools in alleviating poverty. The paper, Microfinance: Development Aid tool is analyzing whether microfinance institutions provide, beside the credit services, also preventive antimalarial services so as to lower malaria cases. Theoretical part is focused on definition and familiarization with 'microfinance, development aid and malaria' terms. Practical part analyses the malaria problem in connection with microfinance market and microfinance organizations in the three above mentioned countries.
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Schaten, Kathrin Maria. "One Health approach to measure the impact on wellbeing of selected infectious diseases in humans and animals in Zambia." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33198.
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This study describes the results of a cross-sectional survey conducted in Mambwe district in the Eastern Province in Zambia. It uses a One Health approach to assess the impact of veterinary, medical, environmental and social determinants on animal and human health and wellbeing. One Health is defined as a holistic and interdisciplinary approach that describes the complexities between people, animals, the environment and their health. Human wellbeing is defined in this thesis as 'a condition in which all members of society are able to determine and meet their needs and have a large range of choices to meet their potential' (Prescott-Allen, 2001). As a first step, eight focus group discussions with the inhabitants followed by key informant interviews with stakeholders in the area were conducted to give a primary impression and narrow down the problems in relation to animal and human health of the area in general. Following this, a randomized selection of 210 households was visited and in each household blood samples were taken from all humans and all animals belonging to five animal species, namely cattle, goats, sheep, pigs and dogs. A third of the households did not keep any of the animal species chosen for sampling, but their inclusion was important for the social analysis. In all of these 210 households a wellbeing questionnaire was administered and, for every human and animal sampled, a health questionnaire. The study area falls within the tsetse-infested region of Zambia. It has a high wildlife density reflecting the proximity of several national parks and is historically endemic for both human and animal African trypanosomiasis (HAT&AAT). Therefore humans and animals were tested for trypanosomiasis using internal transcribed spacer (ITS) polymerase chain reaction (PCR). Since it is important as a differential diagnosis, malaria was tested for by a rapid diagnostic test in the field from human blood. Sera from mature individuals from all animal species except pigs were tested in a field laboratory for brucellosis using the Rose Bengal test. Additionally, cattle and dogs were tested for five genera of tick-borne infections (TBI) including Anaplasma, Ehrlichia, Theileria, Babesia and Rickettsia using reverse line blot (RLB) in the laboratory at the University of Edinburgh (UoE). The blood samples for PCR and RLB analysis at UoE were stored on WhatmanTM FTA cards. A total of 1012 human samples were tested for HAT and none found positive. 1005 (seven people had been tested positive or treated against malaria shortly before the sampling) people tested for malaria showed an overall prevalence of 15% (95% CI 13.2-17.7). None of the 734 Rose Bengal tests showed up positive for brucellosis. The prevalence of AAT in 1275 samples tested was much lower compared to former samplings; in cattle 22% (95% CI 18-27.2), in goats 7% (95% CI 4.5-9.2), in pigs 6% (95% CI 3.2-9.4), in dogs 9% (95% CI 5.2-13.6) and no samples were found positive in sheep. The prevalence of TBIs is much more complex with many multiple infections. A total of 340 cattle and 195 dogs were tested. In cattle the number of samples positive for any microorganism was as follows; 92% (95% CI 88- 94.2). Overall there were fewer positive samples from dogs with 25% of animals infected (95% CI 19.2-31.8). The wellbeing and health questionnaires were designed to help to identify possible risk factors for the above-mentioned diseases and signs, such as fever, diarrhoea and seizures, indicative for several other diseases. The results of these surveys might also help to identify potential reasons for a lower or higher prevalence of trypanosomiasis and malaria found than expected from previous studies. Additionally, information on personal happiness, attitudes towards veterinary and medical services, medical treatments received, education, women's reproductive history, drug abuse, people's perceptions of changes in environment and agriculture, demography, poverty and migration were collected via the questionnaires alongside information on livestock demographics and fertility. One of the main conclusions is that both medical and veterinary health care systems suffer from a number of shortcomings. The distance to appropriate treatment and care facilities is far and the necessary drugs are often unavailable. Also, both the knowledge and technology for diagnosing selected diseases is not in place. This study suggests that neurocysticercosis (NCC) plays an important role in this area due to the high number of seizures reported in people, in whom treatment for epilepsy was unsuccessful. Samples taken from a few pigs indicated the presence of Taenia solium, the causal agent of NCC. Furthermore, many of the TBIs are of zoonotic nature and further investigations must be made to begin to assess the burden of these diseases in humans and animals. Environmental changes such as degradation of the vegetation are likely to have an influence on the prevalence of studied diseases and this aspect is being investigated further in other studies. Due to the nature of a cross-sectional study, only limited conclusions can be drawn on the causal relationships of disease prevalence, but the social analysis conducted in this study confirmed the interactions of selected factors related to health and wealth unique for this study area.
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Chaponda, E. B. "The epidemiology of malaria, curable sexually transmitted and reproductive tract infections and their coinfection among pregnant women in a catchment area in Nchelenge District, Zambia." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2017. http://researchonline.lshtm.ac.uk/4398420/.
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Introduction: Malaria and curable sexually transmitted and reproductive tract infections (STIs/RTIs) are important causes of adverse birth outcomes (ABO) and are both prevalent in most parts of sub-Saharan Africa. From a public health perspective, control of these infections requires interventions that are part of an integrated antenatal care package. The extent to which there may be coinfection increases the importance of such an integrated approach to reduce ABO. A systematic review and meta-analysis published in 2012 showed that the prevalence of malaria and curable STIs/RTIs among antenatal attendees in sub-Saharan Africa is considerable. However, the prevalence of malaria and curable STI/RTI coinfection has not been reported in any epidemiological setting. The primary objective of this thesis is to address this knowledge gap by estimating the prevalence of malaria, curable STIs/RTIs and their coinfection and to highlight the importance of an integrated approach to control malaria and STIs/RTIs in pregnancy. Secondary objectives of the study were to: (1) determine risk factors for malaria, curable STIs/RTIs and their coinfection; (2) estimate the prevalence of ABO and identify risk factors for ABO; (3) measure the in vivo efficacy and the prophylactic effect of sulphadoxine-pyrimethamine (SP) in pregnant women, and (4) characterise the molecular markers associated with parasite resistance to SP among pregnant women. Methods: A prospective cohort study of 1,086 antenatal attendees was conducted in Nchelenge District, Zambia. Consenting women visiting two health centres for their first antenatal care (ANC) visit were screened for malaria and curable STIs/RTIs (Chlamydia, gonorrhoea, trichomoniasis, bacterial vaginosis [BV] and syphilis). Socio-demographic data and maternal characteristics were also collected at enrolment. Sulphadoxine-pyrimethamine was administrated as intermittent preventive treatment to eligible women and they were followed up at day 28 for a second 13 malaria screening to determine the therapeutic and prophylactic failure of SP. At delivery participants were screened for placental malaria and data on birth outcomes were recorded. Univariate and multivariate analyses were conducted to determine the association between the potential risk factors for infection and ABO. Results: Of the 1086 women recruited 729 were successfully followed to delivery. The prevalence of malaria infection measured by microscopy was 31.8% (95% CI, 29.1-34.6) and by PCR was 57.8% (95% CI, 54.9-60.8). The risk of malaria infection was higher among pregnant women recruited from Nchelenge health centre compared to those attending the Kashikishi health centre (adjusted odds ratio [aOR] = 1.81; 95% CI, 1.38-2.37, P < 0.001), and HIV-infected women across health centres had a greater risk of malaria infection compared to HIV-uninfected women (aOR = 1.46; 95%, 1.00-2.13, P = 0.045). Infection with at least one STI/RTI was observed in 64.8% (95% CI, 61-67.4) of the participating women. With the exclusion of BV the prevalence of infection with at least one curable STI was 34.5% (95% CI, 31.7-37.4). Infection with at least one STI was associated with BV. In comparison to uninfected women, women infected with BV were at a higher risk of being infected with at least one STI (aOR 1.44; 95% CI, 1.08-1.92, P = 0.012). HIV-infected women had a higher risk of infection with BV than HIV-uninfected women (aOR 1.87; 95% CI, 1.24-2.83, P = 0.003) and women infected with at least one STI had a higher risk of BV (aOR 1.40; 95% CI (1.07 -1.84, P = 0.01). Among participants with complete results (n=1071), 38.7% (95% CI,35.7-41.6) were coinfected with malaria parasites and at least one STI/RTI; 18.9% (95% CI, 16.5-21.2) were infected with malaria parasites only; 26.0% (95% CI, 23.5-28.8) were infected with at least one STI/RTI but no malaria parasites, and 16.4% (95% CI, 14.1-18.6) had no infection. The risk of malaria and curable STI/RTI coinfection was higher among HIV infected women than HIV-uninfected women (OR; 3.59 [95% CI, 1.73-7.48], P < 0.001). The prevalence of composite ABO was 35.1%. Women shorter than 1.5m were at a higher risk of experiencing at least one ABO (aOR 1.55; 95% CI, 1.10-2.18, P = 0.02). The risk of having ABO among para II was less than half of the risk observed in 14 primiparous women (aOR 0.41; 95% CI, 0.27-0.61, P < 0.001) and much lower among multiparous women (aOR 0.32; 95% CI, 0.22-0.48, P < 0.001). Having taken two or more doses of SP during pregnancy was protective against ABO (aOR 0.47; 95% CI, 0.31-0.72, P = 0.001). None of the infections (malaria, curable STIs/RTIs and their coinfection) diagnosed at first ANC were associated with ABO. The prevalence of highly resistant quintuple mutant was 68.8% among first ANC attendees. Despite the moderate prevalence of the quintuple mutant among pregnant women, SP cleared parasitaemia in 86% of the asymptomatic malaria cases among HIV-negative women Conclusion: The prevalence of malaria, STI/RTI and their coinfection at first ANC in this study population was considerable. However, no association was found between ABO and infection with malaria or STI/RTI or their coinfection. This lack of association is partially a result of interventions within the ANC package including treatment of some STI/RTI, intermittent preventive treatment in pregnancy with SP and iron and folic acid supplementation. Sulphadoxine-pyrimethamine retains partial efficacy against P. falciparum malaria in this area with moderate prevalence of the quintuple mutant. While continuing the policy of offering intermittent preventive treatment with SP during pregnancy, an alternative preventive therapy that is effective against both malaria and STIs/RTIs needs to be considered.
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Wandjowo, Rosie. "Exploring the Role of Aid in the Malawian and Zambian Health Sectors : To what extent does development assistance contribute to aid dependency in Malawi and Zambia?" Thesis, Södertörns högskola, Utveckling och internationellt samarbete, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-41309.
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Aid is an important topic in development sector current discussions are polarised thereby creating a need for further research. This essay assesses the role that Malawi and Zambia plays in realising its development outcomes including in the area of health. There is a need to appreciate the variables that contribute to the inability of most countries in sub-Saharan Africa to finance their domestic expenditure related to healthcare. In this situation, foreign aid which has received marked interest by scholars over the past decade and is used to supplement incomes of developing countries like Malawi and Zambia. Debate on the effectiveness of aid is polarised, while highly concerned scholars see aid as ineffective and a contributor to the poor performance of economies in developing countries, others see it as essential in the achievement of development outcomes. This thesis explores the extent to which development assistance contributes to dependency in Malawi and Zambia. It further examines the link between aid and the Malawian and Zambian health sectors. The study similarly considers the role of development assistance for health in realising outcomes related to maternal health in line with SDG 3.1. By identifying two countries in sub-Saharan Africa, this essay underscores the similarities between Malawi and Zambia analysed through a historical context, health systems structures, child and maternal mortality rates and health programme models. The essay concludesthat social, political and economic barriers present challenges in financing healthcare in Malawi and Zambia. Aid contributes to dependency in the study countries.
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Magwizi, Brenda Thandekha, and Rhodes University. "Exchange rate behavior in the cases of the Zambian Kwacha and Malawian Kwacha : is there misalignment?" Thesis, Rhodes University, 2011. http://hdl.handle.net/10962/d1002708.
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The exchange rate is the price of one currency against another currency or currencies of a group of countries. Real exchange rates are important because they show the external competitiveness of a country‟s economy. Thus, when the exchange rate of a country is misaligned, this will affect its trade, production and the welfare of people. This study analysed macroeconomic determinants of the real exchange rate and dynamic adjustment of the real exchange rate as a result of shocks to these determinants. The study also determined the extent of misalignment of the real exchange rate in Malawi and Zambia and identified variables that contributed to it. Such information is important to policy makers. Quarterly data were used for both countries from 1980:1-2008:4. The literature review identified those variables that determine the exchange rate and these include government consumption, foreign aid, net foreign assets, commodity prices, terms of trade, domestic credit, openness and the Balassa Samuelson effect (technological progress). To determine the long-run relationship between the exchange rate and its determinants, we employed the Johansen approach and the Vector Error Correction Model (VECM). For robustness check on the long-run and shortrun effects of determinants on the exchange rate, variance decomposition and impulse response analyses were used. Results in the study show that in Malawi for both models, an increase in LAID, LGCON and LTOT resulted in real exchange rate depreciation and increases in LDC, NFA and LNEER resulted in an appreciation. In Zambia, increases in LAID, LGCON, LOPEN and LTOT caused the real exchange rate to depreciate while increases in LDC, NFA and LCOPPER led to an appreciation. Lagged LREER and LNEER were found to have short run effects on the equilibrium exchange rate for Malawi and lagged LCOPPER and LDC for Zambia. Periods of exchange rate misalignment were found in both countries. It was also found that the coefficient of speed of adjustment in Malawi in models 1 and 2 indicate that 11% and 27% of the variation in the real exchange rate from its equilibrium adjust each quarter respectively. The speed of adjustment for Zambia in both models was 45% and 47% respectively, higher than that of Malawi. Foreign aid has proven to be important in exchange rate misalignment in both countries, though this was not really expected in the case of Zambia. Given these results, it may be of interest to policy makers to understand which variables impact most on the exchange rate and how misalignment due to these determinants can be minimised.
Books on the topic "Malaria – Zambia"
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Health, Zambia Ministry of. Zambia national malaria indicator survey, 2010. Lusaka, Zambia: Ministry of Health, 2010.
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Zambia. National roll back malaria strategy, 2000-2005, Zambia. [Lusaka]: National Malaria Control Centre, 2000.
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Health, Zambia Ministry of. Guidelines for epidemic preparedness, prevention and control of malaria in Zambia. 2nd ed. Lusaka]: Govt. of the Republic of Zambia, Ministry of Health, 2007.
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Sipilanyambe, Naawa. An evaluation of the socio-economic factors associated with malaria in Zambia. Lusaka: Republic of Zambia, Ministry of Finance and National Planning, 2005.
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Health, Zambia Ministry of. Guidelines for the diagnosis and treatment of malaria in Zambia. 4th ed. [Lusaka]: Ministry of Health, 2014.
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Health, Zambia Ministry of. Guidelines for the diagnosis and treatment of malaria in Zambia. 3rd ed. Lusaka?]: Ministry of Health, 2010.
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Rath, Alison Dembo. Evaluation of the Community-Based Malaria Prevention and Control Project in Samfya District, Luapula Province, Zambia. [Lusaka?]: Malaria Consortium, 1998.
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Kafula, Rodwell. Inter-district accelerated malaria control as part of the Zambian health care package: Strategy Development Workshop, Eastern Province : March 23-25, 1998, Chipata, Zambia : workshop report. Lusaka?: s.n., 1998.
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Health, Zambia Ministry of. A 5-year strategic plan: A road map for impact on malaria in Zambia, 2006-2010 : rapid scale up of malaria control interventions for impact in Zambia. Lusaka: Ministry of Health, 2006.
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Health, Zambia Ministry of. A 5-year strategic plan: A road map for impact on malaria in Zambia, 2006-2010 : rapid scale up of malaria control interventions for impact in Zambia. Lusaka: Ministry of Health, 2006.
Find full textBook chapters on the topic "Malaria – Zambia"
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Schneider, Marius, and Vanessa Ferguson. "Malawi." In Enforcement of Intellectual Property Rights in Africa. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198837336.003.0034.
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Malawi is a landlocked country located within south-east Africa, surrounded by Mozambique, Zambia, and Tanzania, with an area of 118,484 square kilometres (km) for a population of 18.62 million (2017). The capital of Malawi is Lilongwe. With an estimated population of 821,000 it is one of the largest cities in the country. The working week is from Monday to Friday, with business hours running from 0800 until 1700, with a one-hour lunch break. The currency used in Malawi is known as the Malawian kwacha (MWK).
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Schneider, Marius, and Vanessa Ferguson. "Zambia." In Enforcement of Intellectual Property Rights in Africa. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198837336.003.0056.
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Zambia, an independent Republic and landlocked country in south-central Africa, is surrounded by Angola, Zaire, Tanzania, Malawi, Mozambique, Zimbabwe, Botswana, and Namibia. Zambia has a total area of 752,618 square kilometres (km) and an estimated population of 17.09 million (2017). The country’s capital and largest city is Lusaka with an estimated population of 1.8 million. Normal working hours in government and private sector offices are from 0800 to 1300 and 1400 to 1700 between Monday and Friday. The monetary unit is the kwacha (ZMW).
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Arriola, Leonardo R., Martha C. Johnson, and Melanie L. Phillips. "Conclusion." In Women and Power in Africa, 213–44. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780192898074.003.0009.
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The concluding chapter revisits the main hypotheses regarding women’s experiences as aspirants, candidates, and legislators. Complemented by tables summarizing key findings, the chapter identifies where and how the book’s studies of Benin, Burkina Faso, Ghana, Kenya, Malawi, Namibia, Uganda, and Zambia either uphold or contradict hypotheses from the existing literature. Building on this summary, the chapter presents an agenda for future research on women’s political participation in African countries focused on the importance of financial constraints for women’s candidacies, the role of violence in shaping women’s political options, and the impact women in power have on gendered institutions. The book ends on an optimistic note, arguing that despite these barriers, the case studies clearly demonstrate that women are adept at securing a place for themselves, and asserting their voice, in local and national politics.
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Fox, Eleanor M., and Mor Bakhoum. "Eastern and Southern Africa." In Making Markets Work for Africa, 41–88. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190930998.003.0005.
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This chapter focuses on the competition policies of selected countries in Eastern and Southern Africa, specifically Kenya, Namibia, Botswana, Tanzania, Zambia, Zimbabwe, Malawi, and the island of Mauritius. The eastern and southern countries’ competition authorities span a range of functionality, from very high to almost inert. Even the highest functioning competition authorities face severe challenges in terms of financial and human capital, corruption, political pressure to favor government cronies and vested interests, and sometimes war and bankruptcy. Other challenges that competition authorities face concern the privileges of state-owned enterprises (SOEs), corruption through government procurement, and a plethora of not always transparent cross-border restraints. Even though their agendas are crowded by mandatory duties of vetting mergers and authorizing agreements, the best of agencies carve out precious time to identify the most harmful market obstructions and develop strategies to solve them.
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Arriola, Leonardo R., Martha C. Johnson, and Melanie L. Phillips. "Individuals and Institutions." In Women and Power in Africa, 1–36. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780192898074.003.0001.
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Chapter 1 provides a theoretical framework for understanding African women’s experiences within the broader scholarship on women in politics. The chapter discusses, in three stages, the choices African women must make as they aspire to candidacy, campaign in elections, and govern in office. For each stage, the authors review central theories in the literature on women’s representation and discuss how related hypotheses are upheld or contradicted by emerging evidence from African countries. These overviews highlight common empirical findings as well as specific contradictions across the eight countries examined in the book—Benin, Burkina Faso, Ghana, Kenya, Malawi, Namibia, Uganda, and Zambia. The chapter also provides a concise description of each empirical chapter’s core findings with an emphasis on how individual attributes (e.g., professional background, financial autonomy, organizational ties) and institutional structures (e.g., political parties, electoral systems, media organizations, patronage politics) interact to impinge on African women’s political trajectories.
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"List of Figures and Tables." In International Aid and National Decision: Development Programs in Malawi, Tanzania, and Zambia, vii—viii. Princeton: Princeton University Press, 2015. http://dx.doi.org/10.1515/9781400872268-001.
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"List of Abbreviations." In International Aid and National Decision: Development Programs in Malawi, Tanzania, and Zambia, ix—x. Princeton: Princeton University Press, 2015. http://dx.doi.org/10.1515/9781400872268-002.
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"Preface." In International Aid and National Decision: Development Programs in Malawi, Tanzania, and Zambia, xi—xviii. Princeton: Princeton University Press, 2015. http://dx.doi.org/10.1515/9781400872268-003.
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"Acknowledgments." In International Aid and National Decision: Development Programs in Malawi, Tanzania, and Zambia, xix—xx. Princeton: Princeton University Press, 2015. http://dx.doi.org/10.1515/9781400872268-004.
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"1. International Organization and Field Operations." In International Aid and National Decision: Development Programs in Malawi, Tanzania, and Zambia, 1–51. Princeton: Princeton University Press, 2015. http://dx.doi.org/10.1515/9781400872268-005.
Full textConference papers on the topic "Malaria – Zambia"
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Norris, Douglas E. "High burden of malaria following scale-up of control interventions in Nchelenge District, Luapula Province, Zambia." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.93568.
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Chaponda, E., R. Chico, J. Bruce, C. Michelo, and D. Chandramohan. "P220 The burden of HIV on malaria and sexually transmitted and reproductive tract infections among pregnant women of rural, Zambia." In Abstracts for the STI & HIV World Congress, July 14–17 2021. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/sextrans-2021-sti.307.
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Dauenhauer, P. M., D. F. Frame, S. Strachan, M. Dolan, M. Mafuta, D. Chakraverty, and J. Henrikson. "Remote monitoring of off-grid renewable energy Case studies in rural Malawi, Zambia, and Gambia." In 2013 IEEE Global Humanitarian Technology Conference (GHTC). IEEE, 2013. http://dx.doi.org/10.1109/ghtc.2013.6713718.
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Sumarni, Sumarni, and Farida Kartini. "Experience of Adolescent Mothers During Pregnancy: A Scoping Review." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.02.28.
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Background: Every year, around 14 million women and girls aged 15 to 19 (both married and unmarried) give birth. This age group might lead to negative outcomes of pregnancy and childbirth. This scoping review aimed to identify the outcomes of adolescent pregnancy and its contributing factors. Subjects and Method: A scoping review method was conducted in eight stages including (1) Identification of study problems; (2) Determining priority problem and study question; (3) Determining framework; (4) Literature searching; (5) Article selection; (6) Critical appraisal; (7) Data extraction; and (8) Mapping. The research question was identified using population, exposure, and outcome(s) (PEOS) framework. The search included Wiley Online Library, EBSCO, ProQuest, and PubMed databases. The inclusion criteria were English-language and full-text articles published between 2009 and 2019. A total of 307 articles were obtained by the searched database. After the review process, seven articles were eligible for this review. The data were reported by the PRISMA flow chart. Results: Six articles from developing countries (Brazil, Mexico, Zambia, Malawi, and Romania) and one report from developed countries (Australia) met the inclusion criteria with qualitative, quantitative (cross-sectional), and descriptive studies. The existing studies stated that adolescent pregnancy had adverse effects on both mother and babies’ health and well-being. Young maternal age is associated with low parity, lack of prenatal care, premature, and low birth weight. Factors contributed to the increased adolescent pregnancy rate were early sexual initiation, low use of contraception, low educational level, low socioeconomic status, inadequate knowledge about sexual and reproductive health, and gender disparity. Conclusion: Young maternal age contributes to adverse pregnancy outcomes of both mothers and babies. Early sexual health education and health promotion on teenage girls may reduce the risk of adolescent pregnancy rates. Keywords: adolescent pregnancy, birth outcome, maternal age Correspondence: Sumarni. Universitas ‘Aisyiyah Yogyakarta. Jl. Siliwangi (Ringroad Barat) No. 63, Nogotirto, Gamping, Sleman, Yogyakarta, 55292. Email: sumarnipino21@gmail.com. Mobile: +6282346354512. DOI: https://doi.org/10.26911/the7thicph.02.28
Reports on the topic "Malaria – Zambia"
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Ashraf, Nava, Günther Fink, and David Weil. Evaluating the Effects of Large Scale Health Interventions in Developing Countries: The Zambian Malaria Initiative. Cambridge, MA: National Bureau of Economic Research, June 2010. http://dx.doi.org/10.3386/w16069.
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Rohwerder, Brigitte. The Socioeconomic Impacts of the Covid-19 Pandemic on Forcibly Displaced Persons. Institute of Development Studies (IDS), July 2021. http://dx.doi.org/10.19088/cc.2021.006.
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Covid-19 and the response and mitigation efforts taken to contain the virus have triggered a global crisis impacting on all aspects of life. The impact of the Covid-19 pandemic for forcibly displaced persons (refugees, internally displaced persons and asylum seekers) extends beyond its health impacts and includes serious socioeconomic and protection impacts. This rapid review focuses on the available evidence of the socioeconomic impacts of the crisis on forcibly displaced persons, with a focus where possible and relevant on examples from countries of interest to the Covid Collective programme: Afghanistan, Bangladesh, Ghana, Iraq, Kenya, Malawi, Pakistan, Rwanda, South Sudan, Syria, Uganda, Yemen, Zambia and Zimbabwe.
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Carreras, Marco, Amrita Saha, and John Thompson. Rapid Assessment of the Impact of Covid-19 on Food Systems and Rural Livelihoods in Sub-Saharan Africa – Synthesis Report 2. Institute of Development Studies (IDS), December 2020. http://dx.doi.org/10.19088/apra.2020.023.
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This report presents a summary of findings emerging from the second round of a three-wave rapid assessment led by the Agricultural Policy Research in Africa (APRA) Programme of the Future Agricultures Consortium (FAC) in October-November 2020 to examine how COVID-19 is affecting food systems and rural livelihoods in eight countries – Ethiopia, Ghana, Kenya, Malawi, Nigeria, Tanzania, Zambia and Zimbabwe. It builds on a set of phone-based household surveys and key informant interviews conducted in those countries in June-July 2020, which served as the baseline for this research.1 APRA will continue to monitor the situation as the response to the pandemic unfolds through the third round of data collection and analysis planned for the first quarter of 2021.